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Conserved domains on  [gi|1736704024|gb|KAA1062564|]
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aminoimidazole riboside kinase [Enterobacter mori]

Protein Classification

carbohydrate kinase family protein( domain architecture ID 10793260)

carbohydrate kinase family protein that accepts a wide variety of substrates, including carbohydrates and aromatic small molecules, all being phosphorylated at a hydroxyl group; similar to fructokinase and aminoimidazole riboside kinase, which catalyze the phosphorylation of fructose and aminoimidazole ribotide, respectively

CATH:  3.40.1190.20
EC:  2.7.1.-
Gene Ontology:  GO:0016301|GO:0005975
PubMed:  8382990
SCOP:  4000759

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PRK09434 PRK09434
aminoimidazole riboside kinase; Provisional
1-296 0e+00

aminoimidazole riboside kinase; Provisional


:

Pssm-ID: 236514 [Multi-domain]  Cd Length: 304  Bit Score: 564.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   1 MKKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHR 80
Cdd:PRK09434    2 MNKVWVLGDAVVDLIPEGENRYLKCPGGAPANVAVGIARLGGESGFIGRVGDDPFGRFMQQTLQDEGVDTTYLRLDPAHR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  81 TSTVVVDLDDHGERSFTFMVRPSADLFLEPADLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNIRP 160
Cdd:PRK09434   82 TSTVVVDLDDQGERSFTFMVRPSADLFLQPQDLPPFRQGEWLHLCSIALSAEPSRSTTFEAMRRIKAAGGFVSFDPNLRE 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 161 DLWADENELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRCPARLVLVTLGKEGVIAWHDGAVKHYPATSV 240
Cdd:PRK09434  162 DLWQDEAELRECLRQALALADVVKLSEEELCFLSGTSQLEDAIYALADRYPIALLLVTLGAEGVLVHTRGQVQHFPAPSV 241
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1736704024 241 ECVDTTGAGDAFVAGLLYGLAAG------QELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:PRK09434  242 DPVDTTGAGDAFVAGLLAGLSQAglwtdeAELAEIIAQAQACGALATTAKGAMTALPNRQEL 303
 
Name Accession Description Interval E-value
PRK09434 PRK09434
aminoimidazole riboside kinase; Provisional
1-296 0e+00

aminoimidazole riboside kinase; Provisional


Pssm-ID: 236514 [Multi-domain]  Cd Length: 304  Bit Score: 564.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   1 MKKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHR 80
Cdd:PRK09434    2 MNKVWVLGDAVVDLIPEGENRYLKCPGGAPANVAVGIARLGGESGFIGRVGDDPFGRFMQQTLQDEGVDTTYLRLDPAHR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  81 TSTVVVDLDDHGERSFTFMVRPSADLFLEPADLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNIRP 160
Cdd:PRK09434   82 TSTVVVDLDDQGERSFTFMVRPSADLFLQPQDLPPFRQGEWLHLCSIALSAEPSRSTTFEAMRRIKAAGGFVSFDPNLRE 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 161 DLWADENELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRCPARLVLVTLGKEGVIAWHDGAVKHYPATSV 240
Cdd:PRK09434  162 DLWQDEAELRECLRQALALADVVKLSEEELCFLSGTSQLEDAIYALADRYPIALLLVTLGAEGVLVHTRGQVQHFPAPSV 241
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1736704024 241 ECVDTTGAGDAFVAGLLYGLAAG------QELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:PRK09434  242 DPVDTTGAGDAFVAGLLAGLSQAglwtdeAELAEIIAQAQACGALATTAKGAMTALPNRQEL 303
bac_FRK cd01167
Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for ...
3-287 1.03e-107

Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.


Pssm-ID: 238572 [Multi-domain]  Cd Length: 295  Bit Score: 314.57  E-value: 1.03e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGEGRLLQ---CPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAH 79
Cdd:cd01167     1 KVVCFGEALIDFIPEGSGAPETftkAPGGAPANVAVALARLGGKAAFIGKVGDDEFGDFLLETLKEAGVDTRGIQFDPAA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  80 RTSTVVVDLDDHGERSFTFMVRPSADLFLEPADLPS-FSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNI 158
Cdd:cd01167    81 PTTLAFVTLDADGERSFEFYRGPAADLLLDTELNPDlLSEADILHFGSIALASEPSRSALLELLEAAKKAGVLISFDPNL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 159 RPDLWADENELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLmRRCPARLVLVTLGKEGVIAWHDGAVKHYPAT 238
Cdd:cd01167   161 RPPLWRDEEEARERIAELLELADIVKLSDEELELLFGEEDPEEIAALL-LLFGLKLVLVTRGADGALLYTKGGVGEVPGI 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1736704024 239 SVECVDTTGAGDAFVAGLLYGLAAGQ-------ELVPVIGLAQRCGALATTAKGAM 287
Cdd:cd01167   240 PVEVVDTTGAGDAFVAGLLAQLLSRGllaldedELAEALRFANAVGALTCTKAGAI 295
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
3-296 3.42e-90

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 270.22  E-value: 3.42e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGE-----------GRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQ 71
Cdd:COG0524     1 DVLVIGEALVDLVARVDrlpkggetvlaGSFRRSPGGAAANVAVALARLGARVALVGAVGDDPFGDFLLAELRAEGVDTS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  72 QMRLDPAHRTSTVVVDLDDHGERSFTFMvrPSADLFLEPADLPS--FSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAG 149
Cdd:COG0524    81 GVRRDPGAPTGLAFILVDPDGERTIVFY--RGANAELTPEDLDEalLAGADILHLGGITLASEPPREALLAALEAARAAG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 150 GYVSFDPNIRPDLWadeNELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRcPARLVLVTLGKEGVIAWHD 229
Cdd:COG0524   159 VPVSLDPNYRPALW---EPARELLRELLALVDILFPNEEEAELLTGETDPEEAAAALLAR-GVKLVVVTLGAEGALLYTG 234
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1736704024 230 GAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:COG0524   235 GEVVHVPAFPVEVVDTTGAGDAFAAGFLAGLLEGLDLEEALRFANAAAALVVTRPGAQPALPTREEV 301
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
3-288 3.40e-68

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 213.74  E-value: 3.40e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGEG---------RLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQM 73
Cdd:pfam00294   1 KVVVIGEANIDLIGNVEGlpgelvrvsTVEKGPGGKGANVAVALARLGGDVAFIGAVGDDNFGEFLLQELKKEGVDTDYV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  74 RLDPAHRTSTVVVDLDDHGERSFTFMVRPSADLFLEP--ADLPSFSAGEWLHVCSIALSaePSRSAAFQAMTSIREAGGY 151
Cdd:pfam00294  81 VIDEDTRTGTALIEVDGDGERTIVFNRGAAADLTPEEleENEDLLENADLLYISGSLPL--GLPEATLEELIEAAKNGGT 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 152 vsFDPNIRPDLWADenelRRCLELALQHADVVKLSVEELTFLTHDAQVktGLESLMRRCP------ARLVLVTLGKEGVI 225
Cdd:pfam00294 159 --FDPNLLDPLGAA----REALLELLPLADLLKPNEEELEALTGAKLD--DIEEALAALHkllakgIKTVIVTLGADGAL 230
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1736704024 226 AWH-DGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAMT 288
Cdd:pfam00294 231 VVEgDGEVHVPAVPKVKVVDTTGAGDSFVGGFLAGLLAGKSLEEALRFANAAAALVVQKSGAQT 294
myo_inos_iolC_N TIGR04382
5-dehydro-2-deoxygluconokinase; All members of the seed alignment for this model are ...
27-296 8.35e-58

5-dehydro-2-deoxygluconokinase; All members of the seed alignment for this model are translated from the iolC gene of known or putative inositol catabolism operons. Members with characterized function are 5-dehydro-2-deoxygluconokinase, the enzyme catalyzing the fifth step in degradation from myo-inositol or closely related compounds. Note that many members of this family are fusion proteins with an additional C-terminal domain, of unknown function, described by pfam09863. [Energy metabolism, Sugars]


Pssm-ID: 275175 [Multi-domain]  Cd Length: 309  Bit Score: 187.81  E-value: 8.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  27 GGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGERSFTFMVRPSADL 106
Cdd:TIGR04382  34 GGSPANIAVGAARLGLKTAFITRVGDDQFGRFVRDYLRREGVDTSHVVTDPGRRTSLVFLEIKPPDEFPLLFYRENAADL 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 107 FLEPADLPS--FSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNIRPDLWADENELRRCLELALQHADVVK 184
Cdd:TIGR04382 114 ALTPDDVDEdyIASARALLVSGTALSQEPSREAVLKALEYARAAGVRVVLDIDYRPYLWKSPEEAGIYLRLVLPLVDVII 193
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 185 LSVEELTFLTHDAQVKTGLESLMRRCPArLVLVTLGKEGVIAWH-DGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAG 263
Cdd:TIGR04382 194 GTREEFDIAGGEGDDEAAARALLDAGVE-ILVVKRGPEGSLVYTgDGEGVEVPGFPVEVLNVLGAGDAFASGFLYGLLAG 272
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1736704024 264 QELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:TIGR04382 273 WDLEKALRYGNACGAIVVSRHSCSPAMPTLEEL 305
 
Name Accession Description Interval E-value
PRK09434 PRK09434
aminoimidazole riboside kinase; Provisional
1-296 0e+00

aminoimidazole riboside kinase; Provisional


Pssm-ID: 236514 [Multi-domain]  Cd Length: 304  Bit Score: 564.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   1 MKKIWVLGDAVVDLLPDGEGRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHR 80
Cdd:PRK09434    2 MNKVWVLGDAVVDLIPEGENRYLKCPGGAPANVAVGIARLGGESGFIGRVGDDPFGRFMQQTLQDEGVDTTYLRLDPAHR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  81 TSTVVVDLDDHGERSFTFMVRPSADLFLEPADLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNIRP 160
Cdd:PRK09434   82 TSTVVVDLDDQGERSFTFMVRPSADLFLQPQDLPPFRQGEWLHLCSIALSAEPSRSTTFEAMRRIKAAGGFVSFDPNLRE 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 161 DLWADENELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRCPARLVLVTLGKEGVIAWHDGAVKHYPATSV 240
Cdd:PRK09434  162 DLWQDEAELRECLRQALALADVVKLSEEELCFLSGTSQLEDAIYALADRYPIALLLVTLGAEGVLVHTRGQVQHFPAPSV 241
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1736704024 241 ECVDTTGAGDAFVAGLLYGLAAG------QELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:PRK09434  242 DPVDTTGAGDAFVAGLLAGLSQAglwtdeAELAEIIAQAQACGALATTAKGAMTALPNRQEL 303
bac_FRK cd01167
Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for ...
3-287 1.03e-107

Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.


Pssm-ID: 238572 [Multi-domain]  Cd Length: 295  Bit Score: 314.57  E-value: 1.03e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGEGRLLQ---CPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAH 79
Cdd:cd01167     1 KVVCFGEALIDFIPEGSGAPETftkAPGGAPANVAVALARLGGKAAFIGKVGDDEFGDFLLETLKEAGVDTRGIQFDPAA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  80 RTSTVVVDLDDHGERSFTFMVRPSADLFLEPADLPS-FSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNI 158
Cdd:cd01167    81 PTTLAFVTLDADGERSFEFYRGPAADLLLDTELNPDlLSEADILHFGSIALASEPSRSALLELLEAAKKAGVLISFDPNL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 159 RPDLWADENELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLmRRCPARLVLVTLGKEGVIAWHDGAVKHYPAT 238
Cdd:cd01167   161 RPPLWRDEEEARERIAELLELADIVKLSDEELELLFGEEDPEEIAALL-LLFGLKLVLVTRGADGALLYTKGGVGEVPGI 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1736704024 239 SVECVDTTGAGDAFVAGLLYGLAAGQ-------ELVPVIGLAQRCGALATTAKGAM 287
Cdd:cd01167   240 PVEVVDTTGAGDAFVAGLLAQLLSRGllaldedELAEALRFANAVGALTCTKAGAI 295
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
3-296 3.42e-90

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 270.22  E-value: 3.42e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGE-----------GRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQ 71
Cdd:COG0524     1 DVLVIGEALVDLVARVDrlpkggetvlaGSFRRSPGGAAANVAVALARLGARVALVGAVGDDPFGDFLLAELRAEGVDTS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  72 QMRLDPAHRTSTVVVDLDDHGERSFTFMvrPSADLFLEPADLPS--FSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAG 149
Cdd:COG0524    81 GVRRDPGAPTGLAFILVDPDGERTIVFY--RGANAELTPEDLDEalLAGADILHLGGITLASEPPREALLAALEAARAAG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 150 GYVSFDPNIRPDLWadeNELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRcPARLVLVTLGKEGVIAWHD 229
Cdd:COG0524   159 VPVSLDPNYRPALW---EPARELLRELLALVDILFPNEEEAELLTGETDPEEAAAALLAR-GVKLVVVTLGAEGALLYTG 234
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1736704024 230 GAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:COG0524   235 GEVVHVPAFPVEVVDTTGAGDAFAAGFLAGLLEGLDLEEALRFANAAAALVVTRPGAQPALPTREEV 301
PLN02323 PLN02323
probable fructokinase
7-291 2.06e-76

probable fructokinase


Pssm-ID: 215183 [Multi-domain]  Cd Length: 330  Bit Score: 236.06  E-value: 2.06e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   7 LGDAVVDLLPDGEG-------RLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAH 79
Cdd:PLN02323   16 FGEMLIDFVPTVSGvslaeapAFKKAPGGAPANVAVGISRLGGSSAFIGKVGDDEFGHMLADILKKNGVNNEGVRFDPGA 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  80 RTSTVVVDLDDHGERSFTFMVRPSADLFLEPA--DLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPN 157
Cdd:PLN02323   96 RTALAFVTLRSDGEREFMFYRNPSADMLLRESelDLDLIRKAKIFHYGSISLITEPCRSAHLAAMKIAKEAGALLSYDPN 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 158 IRPDLWADENELRRCLELALQHADVVKLSVEELTFLTHDAQVKtgLESLMRRCPAR--LVLVTLGKEGVIAWHDGAVKHY 235
Cdd:PLN02323  176 LRLPLWPSAEAAREGIMSIWDEADIIKVSDEEVEFLTGGDDPD--DDTVVKLWHPNlkLLLVTEGEEGCRYYTKDFKGRV 253
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1736704024 236 PATSVECVDTTGAGDAFVAGLLYGLAAGQELV-------PVIGLAQRCGALATTAKGAMTALP 291
Cdd:PLN02323  254 EGFKVKAVDTTGAGDAFVGGLLSQLAKDLSLLedeerlrEALRFANACGAITTTERGAIPALP 316
KdgK cd01166
2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form ...
3-287 1.19e-74

2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.


Pssm-ID: 238571 [Multi-domain]  Cd Length: 294  Bit Score: 230.54  E-value: 1.19e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGEGRLLQC------PGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLD 76
Cdd:cd01166     1 DVVTIGEVMVDLSPPGGGRLEQAdsfrkfFGGAEANVAVGLARLGHRVALVTAVGDDPFGRFILAELRREGVDTSHVRVD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  77 PAHRTSTVVVDLDDHGERSFTFMVRPSADLFLEPADLP--SFSAGEWLHVCSIALSAEPS-RSAAFQAMTSIREAGGYVS 153
Cdd:cd01166    81 PGRPTGLYFLEIGAGGERRVLYYRAGSAASRLTPEDLDeaALAGADHLHLSGITLALSESaREALLEALEAAKARGVTVS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 154 FDPNIRPDLWADEnELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRCP-ARLVLVTLGKEGVIAWHDGAV 232
Cdd:cd01166   161 FDLNYRPKLWSAE-EAREALEELLPYVDIVLPSEEEAEALLGDEDPTDAAERALALALgVKAVVVKLGAEGALVYTGGGR 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1736704024 233 KHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAM 287
Cdd:cd01166   240 VFVPAYPVEVVDTTGAGDAFAAGFLAGLLEGWDLEEALRFANAAAALVVTRPGDI 294
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
3-288 3.40e-68

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 213.74  E-value: 3.40e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGEG---------RLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQM 73
Cdd:pfam00294   1 KVVVIGEANIDLIGNVEGlpgelvrvsTVEKGPGGKGANVAVALARLGGDVAFIGAVGDDNFGEFLLQELKKEGVDTDYV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  74 RLDPAHRTSTVVVDLDDHGERSFTFMVRPSADLFLEP--ADLPSFSAGEWLHVCSIALSaePSRSAAFQAMTSIREAGGY 151
Cdd:pfam00294  81 VIDEDTRTGTALIEVDGDGERTIVFNRGAAADLTPEEleENEDLLENADLLYISGSLPL--GLPEATLEELIEAAKNGGT 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 152 vsFDPNIRPDLWADenelRRCLELALQHADVVKLSVEELTFLTHDAQVktGLESLMRRCP------ARLVLVTLGKEGVI 225
Cdd:pfam00294 159 --FDPNLLDPLGAA----REALLELLPLADLLKPNEEELEALTGAKLD--DIEEALAALHkllakgIKTVIVTLGADGAL 230
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1736704024 226 AWH-DGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAMT 288
Cdd:pfam00294 231 VVEgDGEVHVPAVPKVKVVDTTGAGDSFVGGFLAGLLAGKSLEEALRFANAAAALVVQKSGAQT 294
myo_inos_iolC_N TIGR04382
5-dehydro-2-deoxygluconokinase; All members of the seed alignment for this model are ...
27-296 8.35e-58

5-dehydro-2-deoxygluconokinase; All members of the seed alignment for this model are translated from the iolC gene of known or putative inositol catabolism operons. Members with characterized function are 5-dehydro-2-deoxygluconokinase, the enzyme catalyzing the fifth step in degradation from myo-inositol or closely related compounds. Note that many members of this family are fusion proteins with an additional C-terminal domain, of unknown function, described by pfam09863. [Energy metabolism, Sugars]


Pssm-ID: 275175 [Multi-domain]  Cd Length: 309  Bit Score: 187.81  E-value: 8.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  27 GGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGERSFTFMVRPSADL 106
Cdd:TIGR04382  34 GGSPANIAVGAARLGLKTAFITRVGDDQFGRFVRDYLRREGVDTSHVVTDPGRRTSLVFLEIKPPDEFPLLFYRENAADL 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 107 FLEPADLPS--FSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNIRPDLWADENELRRCLELALQHADVVK 184
Cdd:TIGR04382 114 ALTPDDVDEdyIASARALLVSGTALSQEPSREAVLKALEYARAAGVRVVLDIDYRPYLWKSPEEAGIYLRLVLPLVDVII 193
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 185 LSVEELTFLTHDAQVKTGLESLMRRCPArLVLVTLGKEGVIAWH-DGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAG 263
Cdd:TIGR04382 194 GTREEFDIAGGEGDDEAAARALLDAGVE-ILVVKRGPEGSLVYTgDGEGVEVPGFPVEVLNVLGAGDAFASGFLYGLLAG 272
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1736704024 264 QELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:TIGR04382 273 WDLEKALRYGNACGAIVVSRHSCSPAMPTLEEL 305
ribokinase cd01174
Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This ...
3-292 8.19e-45

Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.


Pssm-ID: 238579 [Multi-domain]  Cd Length: 292  Bit Score: 153.47  E-value: 8.19e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDL------LPD-GE----GRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQ 71
Cdd:cd01174     1 KVVVVGSINVDLvtrvdrLPKpGEtvlgSSFETGPGGKGANQAVAAARLGARVAMIGAVGDDAFGDELLENLREEGIDVS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  72 QMRLDPAHRTSTVVVDLDDHGERSFtfMVRPSADLFLEPADLPSfsAGEWLHVCSIALS-AEPSRSAAFQAMTSIREAGG 150
Cdd:cd01174    81 YVEVVVGAPTGTAVITVDESGENRI--VVVPGANGELTPADVDA--ALELIAAADVLLLqLEIPLETVLAALRAARRAGV 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 151 YVSFDPN-IRPDLwadeNELrrclelaLQHADVVKLSVEELTFLTHD-----AQVKTGLESLMRRcPARLVLVTLGKEGV 224
Cdd:cd01174   157 TVILNPApARPLP----AEL-------LALVDILVPNETEAALLTGIevtdeEDAEKAARLLLAK-GVKNVIVTLGAKGA 224
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1736704024 225 IAWHDGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAMTALPY 292
Cdd:cd01174   225 LLASGGEVEHVPAFKVKAVDTTGAGDTFIGALAAALARGLSLEEAIRFANAAAALSVTRPGAQPSIPT 292
ribokinase_group_A cd01942
Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ...
26-286 6.47e-39

Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238917 [Multi-domain]  Cd Length: 279  Bit Score: 137.83  E-value: 6.47e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGERSFTFMvrPSAD 105
Cdd:cd01942    35 FGGSAGNTAVALAKLGLSPGLVAAVGEDFHGRLYLEELREEGVDTSHVRVVDEDSTGVAFILTDGDDNQIAYFY--PGAM 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 106 LFLEPAD-LPSFSAGEWLHVcsialsaePSRSAAFQAMTSIREAGGYVSFDPNirPDLWADENE-LRRCLElalqHADVV 183
Cdd:cd01942   113 DELEPNDeADPDGLADIVHL--------SSGPGLIELARELAAGGITVSFDPG--QELPRLSGEeLEEILE----RADIL 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 184 KLSVEELTFLTHdaqvKTGLESLMRRCPARLVLVTLGKEGVIAWHDGAVKHYPAT-SVECVDTTGAGDAFVAGLLYGLAA 262
Cdd:cd01942   179 FVNDYEAELLKE----RTGLSEAELASGVRVVVVTLGPKGAIVFEDGEEVEVPAVpAVKVVDTTGAGDAFRAGFLYGLLR 254
                         250       260
                  ....*....|....*....|....
gi 1736704024 263 GQELVPVIGLAQRCGALATTAKGA 286
Cdd:cd01942   255 GYDLEESLRLGNLAASLKVERRGA 278
D_ribokin_bact TIGR02152
ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose ...
26-296 3.01e-37

ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars]


Pssm-ID: 274000 [Multi-domain]  Cd Length: 293  Bit Score: 133.88  E-value: 3.01e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGERSFtfMVRPSAD 105
Cdd:TIGR02152  30 PGGKGANQAVAAARLGAEVSMIGKVGDDAFGDELLENLKSNGIDTEYVGTVKDTPTGTAFITVDDTGENRI--VVVAGAN 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 106 LFLEPADLPSfsAGEWLHVCSIAL----SAEPSRSAAFQAMtsiREAGGYVSFDP-----NIRPDLWAD-------ENEL 169
Cdd:TIGR02152 108 AELTPEDIDA--AEALIAESDIVLlqleIPLETVLEAAKIA---KKHGVKVILNPapaikDLDDELLSLvdiitpnETEA 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 170 rrclelalqhadvvklsvEELT--FLTHDAQVKTGLESLMRRCPaRLVLVTLGKEGVIaWHDGA-VKHYPATSVECVDTT 246
Cdd:TIGR02152 183 ------------------EILTgiEVTDEEDAEKAAEKLLEKGV-KNVIITLGSKGAL-LVSKDeSKLIPAFKVKAVDTT 242
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1736704024 247 GAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:TIGR02152 243 AAGDTFNGAFAVALAEGKSLEDAIRFANAAAAISVTRKGAQSSIPYLEEV 292
adenosine_kinase cd01168
Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside ...
21-286 1.25e-31

Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine levels and the preservation of intracellular adenylate pools. Adenosine kinase is involved in the purine salvage pathway.


Pssm-ID: 238573 [Multi-domain]  Cd Length: 312  Bit Score: 119.64  E-value: 1.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  21 RLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHrTSTVVVDLDDHGERSFTFMV 100
Cdd:cd01168    49 PVKYIAGGSAANTIRGAAALGGSAAFIGRVGDDKLGDFLLKDLRAAGVDTRYQVQPDGP-TGTCAVLVTPDAERTMCTYL 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 101 RPSADLFLEPADLPSFSAGEWLHVCSIALSAEPsrSAAFQAMTSIREAGGYVSFDpnirpdlWADENELRRC---LELAL 177
Cdd:cd01168   128 GAANELSPDDLDWSLLAKAKYLYLEGYLLTVPP--EAILLAAEHAKENGVKIALN-------LSAPFIVQRFkeaLLELL 198
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 178 QHADVV---KLSVEELTFLTHDAQVKTGLESLMRRCpaRLVLVTLGKEGVIAWHDGAVKHYPA-TSVECVDTTGAGDAFV 253
Cdd:cd01168   199 PYVDILfgnEEEAEALAEAETTDDLEAALKLLALRC--RIVVITQGAKGAVVVEGGEVYPVPAiPVEKIVDTNGAGDAFA 276
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1736704024 254 AGLLYGLAAGQELVPVIGLAQRCGALATTAKGA 286
Cdd:cd01168   277 GGFLYGLVQGEPLEECIRLGSYAAAEVIQQLGP 309
PRK09813 PRK09813
fructoselysine 6-kinase; Provisional
2-286 3.64e-31

fructoselysine 6-kinase; Provisional


Pssm-ID: 182090 [Multi-domain]  Cd Length: 260  Bit Score: 117.15  E-value: 3.64e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   2 KKIWVLGDAVVDLLPDgEGRllQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAhRT 81
Cdd:PRK09813    1 KKLATIGDNCVDIYPQ-LGK--AFSGGNAVNVAVYCTRYGIQPGCITWVGDDDYGTKLKQDLARMGVDISHVHTKHG-VT 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  82 STVVVDLDD----HGERSFTFMvrpsADLFLEPADLpSFSAGEWLHVCSIALSAEpsrsaafQAMTSIREAGGYVSFDPN 157
Cdd:PRK09813   77 AQTQVELHDndrvFGDYTEGVM----ADFALSEEDY-AWLAQYDIVHAAIWGHAE-------DAFPQLHAAGKLTAFDFS 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 158 IRPD--LWadenelrrclELALQHADvvklsveeLTFLTHDAQVKTgLESLMRR---CPARLVLVTLGKEGVIAWhDGA- 231
Cdd:PRK09813  145 DKWDspLW----------QTLVPHLD--------YAFASAPQEDEF-LRLKMKAivaRGAGVVIVTLGENGSIAW-DGAq 204
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1736704024 232 VKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGA 286
Cdd:PRK09813  205 FWRQAPEPVTVVDTMGAGDSFIAGFLCGWLAGMTLPQAMAQGTACAAKTIQYHGA 259
Fructoselysine_kinase_like cd01940
Fructoselysine kinase-like. Fructoselysine is a fructoseamine formed by glycation, a ...
7-268 2.65e-30

Fructoselysine kinase-like. Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the lysine side chains. Fructoseamines are typically metabolized by fructoseamine-3-kinase, especially in higher eukaryotes. In E. coli, fructoselysine kinase has been shown in vitro to catalyze the phosphorylation of fructoselysine. It is proposed that fructoselysine is released from glycated proteins during human digestion and is partly metabolized by bacteria in the hind gut using a protein such as fructoselysine kinase. This family is found only in bacterial sequences, and its oligomeric state is currently unknown.


Pssm-ID: 238915 [Multi-domain]  Cd Length: 264  Bit Score: 114.76  E-value: 2.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   7 LGDAVVDLLP-DGEGRllqcPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLdpAHRTSTVV 85
Cdd:cd01940     5 IGDNVVDKYLhLGKMY----PGGNALNVAVYAKRLGHESAYIGAVGNDDAGAHVRSTLKRLGVDISHCRV--KEGENAVA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  86 VDLDDHGERSFTFMVR-PSADLFLEPADLPSFSAGEWLHVCSiaLSAEPSRSAAFQAMTSireAGGYVSFDPNIRpdlWA 164
Cdd:cd01940    79 DVELVDGDRIFGLSNKgGVAREHPFEADLEYLSQFDLVHTGI--YSHEGHLEKALQALVG---AGALISFDFSDR---WD 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 165 DENelrrcLELALQHADVVKLSVEELTflthDAQVKTGLESLMRRcPARLVLVTLGKEGVIAWHDGAVKHYPATSVECVD 244
Cdd:cd01940   151 DDY-----LQLVCPYVDFAFFSASDLS----DEEVKAKLKEAVSR-GAKLVIVTRGEDGAIAYDGAVFYSVAPRPVEVVD 220
                         250       260
                  ....*....|....*....|....
gi 1736704024 245 TTGAGDAFVAGLLYGLAAGQELVP 268
Cdd:cd01940   221 TLGAGDSFIAGFLLSLLAGGTAIA 244
ribokinase_group_B cd01945
Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ...
27-292 8.42e-28

Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .


Pssm-ID: 238920 [Multi-domain]  Cd Length: 284  Bit Score: 108.54  E-value: 8.42e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  27 GGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDlDDHGERSFTFMVRpsADL 106
Cdd:cd01945    36 GGNAANAAVAVARLGGQARLIGVVGDDAIGRLILAELAAEGVDTSFIVVAPGARSPISSIT-DITGDRATISITA--IDT 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 107 FLEPADLPSFSagewLHVCSIALSAEPSRSAAFQAMTSIREAGgyvsfdpnIRPDLWADENELRRCLELaLQHADVVKLS 186
Cdd:cd01945   113 QAAPDSLPDAI----LGGADAVLVDGRQPEAALHLAQEARARG--------IPIPLDLDGGGLRVLEEL-LPLADHAICS 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 187 VEELTFLTHDAQVKTGLesLMRRCPARLVLVTLGKEGVIAWH-DGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQE 265
Cdd:cd01945   180 ENFLRPNTGSADDEALE--LLASLGIPFVAVTLGEAGCLWLErDGELFHVPAFPVEVVDTTGAGDVFHGAFAHALAEGMP 257
                         250       260
                  ....*....|....*....|....*..
gi 1736704024 266 LVPVIGLAQRCGALATTAKGAMTALPY 292
Cdd:cd01945   258 LREALRFASAAAALKCRGLGGRAGLPT 284
Guanosine_kinase_like cd01947
Guanosine kinase-like sugar kinases. Found in bacteria and archaea, the guanosine kinase-like ...
26-286 1.34e-25

Guanosine kinase-like sugar kinases. Found in bacteria and archaea, the guanosine kinase-like group is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238922 [Multi-domain]  Cd Length: 265  Bit Score: 102.50  E-value: 1.34e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQ-QMRLDPAHRTSTVVvdlDDHGERSFTFMVRPSA 104
Cdd:cd01947    35 PGGGGANVAVQLAKLGNDVRFFSNLGRDEIGIQSLEELESGGDKHTvAWRDKPTRKTLSFI---DPNGERTITVPGERLE 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 105 DLFlepaDLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTsIREAGGYVSFDPnirpdlwadenelrrcLELALQHADVVK 184
Cdd:cd01947   112 DDL----KWPILDEGDGVFITAAAVDKEAIRKCRETKLV-ILQVTPRVRVDE----------------LNQALIPLDILI 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 185 LSVEELTFLTHdaqvktGLESLMRRcpARLVLVTLGKEGVIAWHDGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQ 264
Cdd:cd01947   171 GSRLDPGELVV------AEKIAGPF--PRYLIVTEGELGAILYPGGRYNHVPAKKAKVPDSTGAGDSFAAGFIYGLLKGW 242
                         250       260
                  ....*....|....*....|..
gi 1736704024 265 ELVPVIGLAQRCGALATTAKGA 286
Cdd:cd01947   243 SIEEALELGAQCGAICVSHFGP 264
PLN02543 PLN02543
pfkB-type carbohydrate kinase family protein
26-266 2.37e-25

pfkB-type carbohydrate kinase family protein


Pssm-ID: 215299  Cd Length: 496  Bit Score: 104.99  E-value: 2.37e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTST--VVVDLDDhGERSFTFMVRPS 103
Cdd:PLN02543  171 PGGPPSNVAISHVRLGGRAAFMGKVGDDDFGEELVLMMNKERVQTRAVKFDENAKTACsrMKIKFRD-GGKMVAETVKEA 249
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 104 AD--LFLEPADLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNIRPDLWADENELRRCLELALQHAD 181
Cdd:PLN02543  250 AEdsLLASELNLAVLKEARMFHFNSEVLTSPSMQSTLFRAIELSKKFGGLIFFDLNLPLPLWRSRDETRELIKKAWNEAD 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 182 VVKLSVEELTF-LTHDAQVKTgleslmRRCPARLVLVTLG-------------KEGVIAWHDG-----------AVKHYP 236
Cdd:PLN02543  330 IIEVSRQELEFlLDEDYYERK------RNYPPQYYAESFEqtknwrdyyhytpEEIAPLWHDGlklllvtdgtlRIHYYT 403
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1736704024 237 ATSVECV-------------DTTGAGDAFVAGLLYGLAAGQEL 266
Cdd:PLN02543  404 PKFDGVVvgtedvlitpftcDRTGSGDAVVAAIMRKLTTCPEM 446
PLN02341 PLN02341
pfkB-type carbohydrate kinase family protein
28-286 1.69e-24

pfkB-type carbohydrate kinase family protein


Pssm-ID: 215195 [Multi-domain]  Cd Length: 470  Bit Score: 102.60  E-value: 1.69e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  28 GAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEV--------QQMRLDPAHRT--STVVVD-LDDHGersf 96
Cdd:PLN02341  120 GGNCNFAIAAARLGLRCSTIGHVGDEIYGKFLLDVLAEEGISVvgliegtdAGDSSSASYETllCWVLVDpLQRHG---- 195
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  97 tFMVRpsADLFLEPA-----DLPSfSAGEWLHVCSIALSA-----EPSRSAAFQAMTSIREAGGYVSFDPNIRPDLWADE 166
Cdd:PLN02341  196 -FCSR--ADFGPEPAfswisKLSA-EAKMAIRQSKALFCNgyvfdELSPSAIASAVDYAIDVGTAVFFDPGPRGKSLLVG 271
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 167 -NELRRCLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRR-CPARLVLVTLGKEGVIAWHDGAVKHYPATSVECVD 244
Cdd:PLN02341  272 tPDERRALEHLLRMSDVLLLTSEEAEALTGIRNPILAGQELLRPgIRTKWVVVKMGSKGSILVTRSSVSCAPAFKVNVVD 351
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1736704024 245 TTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGA 286
Cdd:PLN02341  352 TVGCGDSFAAAIALGYIHNLPLVNTLTLANAVGAATAMGCGA 393
PTZ00292 PTZ00292
ribokinase; Provisional
27-296 1.39e-21

ribokinase; Provisional


Pssm-ID: 185541 [Multi-domain]  Cd Length: 326  Bit Score: 92.49  E-value: 1.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  27 GGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMrldpaHRTSTVVVDLD----DHGERSFTFMVRP 102
Cdd:PTZ00292   52 GGKGANQAVMASKLGAKVAMVGMVGTDGFGSDTIKNFKRNGVNTSFV-----SRTENSSTGLAmifvDTKTGNNEIVIIP 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 103 SADLFLEPADLpSFSAGEWLHVCSIAL-SAEPSRSAAFQAMTSIREAGGYVSFdpNIRPDLWADENELRRCLelaLQHAD 181
Cdd:PTZ00292  127 GANNALTPQMV-DAQTDNIQNICKYLIcQNEIPLETTLDALKEAKERGCYTVF--NPAPAPKLAEVEIIKPF---LKYVS 200
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 182 VVKLSVEELTFLT----HDAQVKTGLESLMRRCPARLVLVTLGKEG-VIAWHDGAVKHYPATSVECVDTTGAGDAFVAGL 256
Cdd:PTZ00292  201 LFCVNEVEAALITgmevTDTESAFKASKELQQLGVENVIITLGANGcLIVEKENEPVHVPGKRVKAVDTTGAGDCFVGSM 280
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1736704024 257 LYGLAAGQELVPVIGLAQRCGALATTAKGAMTALPYHHEL 296
Cdd:PTZ00292  281 AYFMSRGKDLKESCKRANRIAAISVTRHGTQSSYPHPSEL 320
PRK11142 PRK11142
ribokinase; Provisional
1-296 1.56e-20

ribokinase; Provisional


Pssm-ID: 236858 [Multi-domain]  Cd Length: 306  Bit Score: 89.16  E-value: 1.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   1 MKKIWVLGDAVVD------LLPD-GE---GRLLQC-PGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVE 69
Cdd:PRK11142    2 MGKLVVLGSINADhvlnleSFPRpGEtltGRHYQVaFGGKGANQAVAAARLGADIAFIACVGDDSIGESMRQQLAKDGID 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  70 VQQMRLDPAHRTSTVVVDLDDHGERSFTfmVRPSADLFLEPADLPSFSA----GEWLhvcsiALSAEPSRSAAFQAMTSI 145
Cdd:PRK11142   82 TAPVSVIKGESTGVALIFVNDEGENSIG--IHAGANAALTPALVEAHRElianADAL-----LMQLETPLETVLAAAKIA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 146 REAGGYVSFDPnirpdlwADENELRrcLELaLQHADVVKLSVEELTFLT-------HDAQV------KTGLESlmrrcpa 212
Cdd:PRK11142  155 KQHGTKVILNP-------APARELP--DEL-LALVDIITPNETEAEKLTgirveddDDAAKaaqvlhQKGIET------- 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 213 rlVLVTLGKEGVIAWHDGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGAMTALPY 292
Cdd:PRK11142  218 --VLITLGSRGVWLSENGEGQRVPGFRVQAVDTIAAGDTFNGALVTALLEGKPLPEAIRFAHAAAAIAVTRKGAQPSIPW 295

                  ....
gi 1736704024 293 HHEL 296
Cdd:PRK11142  296 REEI 299
IolC COG3892
Myo-inositol catabolism protein LolC [Carbohydrate transport and metabolism];
27-280 2.52e-20

Myo-inositol catabolism protein LolC [Carbohydrate transport and metabolism];


Pssm-ID: 443099 [Multi-domain]  Cd Length: 640  Bit Score: 90.72  E-value: 2.52e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  27 GGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGERSFTFMVRPSADL 106
Cdd:COG3892    38 GGSSGNIAYGTARLGLKSAMLTRVGDEHMGRFLREELEREGVDTSGVVTDPERLTALVLLGIRDDETFPLIFYRENCADM 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 107 FLEPADlpsFSAGEWLHVCSIA-----LSAEPSRSAAFQAMTSIREAGGYVSFDPNIRPDLW-------------ADENE 168
Cdd:COG3892   118 ALTEDD---IDEAFIASARALLitgthLSHPRTRAAVLKALRYARAHGGKVVLDIDYRPVLWgltghgdgetrfvASDAV 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 169 LRRcLELALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRCPARLVLVTLGK-----EGVI--AWHDGAVkhYPATSVE 241
Cdd:COG3892   195 TAH-LQEVLPLFDLIVGTEEEFHIAGGSTDTLAALRAVRRVSTATLVCKRGALgcvvfEGAIpdDLDDGIT--GPGFPVE 271
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1736704024 242 CVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALA 280
Cdd:COG3892   272 VFNVLGAGDAFMSGFLRGWLRGESWETACAYANACGALV 310
RfaE COG2870
ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell wall/membrane ...
26-280 1.27e-19

ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442117 [Multi-domain]  Cd Length: 321  Bit Score: 87.17  E-value: 1.27e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGApANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTST---VVVDLD-----DHGERSFT 97
Cdd:COG2870    55 PGGA-ANVAANLAALGAQVTLVGVVGDDEAGRELRRLLEEAGIDTDGLVVDPRRPTTTktrVIAGGQqllrlDFEDRFPL 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  98 FMVRPSADLFLEPADLPSFSAGewlhVCS----IALSAEPSRSAAFQAmtsiREAGGYVSFDPNiRPDLWAdenelrrcl 173
Cdd:COG2870   134 SAELEARLLAALEAALPEVDAV----ILSdygkGVLTPELIQALIALA----RAAGKPVLVDPK-GRDFSR--------- 195
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 174 elaLQHADVVKLSVEELTFLTH-----DAQVKTGLESLMRRCPARLVLVTLGKEGV-IAWHDGAVKHYPATSVECVDTTG 247
Cdd:COG2870   196 ---YRGATLLTPNLKEAEAAVGipiadEEELVAAAAELLERLGLEALLVTRGEEGMtLFDADGPPHHLPAQAREVFDVTG 272
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1736704024 248 AGDAFVAGLLYGLAAGQELVPVIGLAQRCGALA 280
Cdd:COG2870   273 AGDTVIATLALALAAGASLEEAAELANLAAGIV 305
ribokinase_group_D cd01937
Ribokinase-like subgroup D. Found in bacteria and archaea, this subgroup is part of the ...
3-267 1.64e-19

Ribokinase-like subgroup D. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238912 [Multi-domain]  Cd Length: 254  Bit Score: 85.53  E-value: 1.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDLLPDGEGRLLQcPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVqqmrlDPAHRTS 82
Cdd:cd01937     1 KIVIIGHVTIDEIVTNGSGVVK-PGGPATYASLTLSRLGLTVKLVTKVGRDYPDKWSDLFDNGIEVIS-----LLSTETT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  83 TVVVDLDDHGeRSFTFMVRPSADLFLEPADlpSFSAGEWLHVCSIALSAEPSrsaafqamtsIREAGGYVSFDPN--IRP 160
Cdd:cd01937    75 TFELNYTNEG-RTRTLLAKCAAIPDTESPL--STITAEIVILGPVPEEISPS----------LFRKFAFISLDAQgfLRR 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 161 dlWADENELRRcleLALQHADVVKLSVEELtflthdAQVKTGLES--LMRRCPARLVLVTLGKEGVIAWHDGAVKHYPAT 238
Cdd:cd01937   142 --ANQEKLIKC---VILKLHDVLKLSRVEA------EVISTPTELarLIKETGVKEIIVTDGEEGGYIFDGNGKYTIPAS 210
                         250       260
                  ....*....|....*....|....*....
gi 1736704024 239 SVECVDTTGAGDAFVAGLLYGLAAGQELV 267
Cdd:cd01937   211 KKDVVDPTGAGDVFLAAFLYSRLSGKDIK 239
FruK COG1105
1-phosphofructokinase or 6-phosphofructokinase II [Carbohydrate transport and metabolism];
26-286 1.70e-19

1-phosphofructokinase or 6-phosphofructokinase II [Carbohydrate transport and metabolism];


Pssm-ID: 440722 [Multi-domain]  Cd Length: 304  Bit Score: 86.34  E-value: 1.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPANVAVGVARLGGNS---AFIGrvGDDpfGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGErsfTfmvrp 102
Cdd:COG1105    34 PGGKGINVARVLKALGVDVtalGFLG--GFT--GEFIEELLDEEGIPTDFVPIEGETRINIKIVDPSDGTE---T----- 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 103 sadLFLEPAdlPSFSAGEWlhvcsialsaepsrSAAFQAMTSIREAGGYV----SFDPNIRPDLWAD------ENELR-- 170
Cdd:COG1105   102 ---EINEPG--PEISEEEL--------------EALLERLEELLKEGDWVvlsgSLPPGVPPDFYAElirlarARGAKvv 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 171 -----RCLELALQ-HADVVKLSVEELTFLTH-----DAQVKTGLESLMRRcPARLVLVTLGKEGVIAWHDGAVKHYPATS 239
Cdd:COG1105   163 ldtsgEALKAALEaGPDLIKPNLEELEELLGrpletLEDIIAAARELLER-GAENVVVSLGADGALLVTEDGVYRAKPPK 241
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1736704024 240 VECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGA 286
Cdd:COG1105   242 VEVVSTVGAGDSMVAGFLAGLARGLDLEEALRLAVAAGAAAALSPGT 288
PLN02967 PLN02967
kinase
21-281 8.42e-19

kinase


Pssm-ID: 215521 [Multi-domain]  Cd Length: 581  Bit Score: 86.25  E-value: 8.42e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  21 RLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGERSFTfMV 100
Cdd:PLN02967  237 KFVRAPGGSAGGVAIALASLGGKVAFMGKLGDDDYGQAMLYYLNVNKVQTRSVCIDGKRATAVSTMKIAKRGRLKTT-CV 315
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 101 RPSADLFLEPADLPS--FSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDPNIRPDLWADENELRRCLELALQ 178
Cdd:PLN02967  316 KPCAEDSLSKSEINIdvLKEAKMFYFNTHSLLDPTMRSTTLRAIKISKKLGGVIFYDLNLPLPLWSSSEETKSFIQEAWN 395
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 179 HADVVKLSVEELTFL-------------------TH-DAQVKTGL--ESLmrrcpaRLVLVTLGKEGVIAW---HDGAVK 233
Cdd:PLN02967  396 LADIIEVTKQELEFLcgiepteefdtkdndkskfVHySPEVVAPLwhENL------KVLFVTNGTSKIHYYtkeHNGAVH 469
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1736704024 234 ---HYPATSVECvDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALAT 281
Cdd:PLN02967  470 gmeDAPITPFTS-DMSASGDGIVAGLMRMLTVQPHLITDKGYLEKTIKYAI 519
RfaE_like cd01172
RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the ...
26-280 1.22e-18

RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer membrane of gram-negative bacteria. RfaE consists of two domains, a sugar kinase domain, represented here, and a domain belonging to the cytidylyltransferase superfamily.


Pssm-ID: 238577 [Multi-domain]  Cd Length: 304  Bit Score: 84.15  E-value: 1.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGApANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRlDPAHRTST---VVVD--------------L 88
Cdd:cd01172    39 LGGA-ANVANNLASLGAKVTLLGVVGDDEAGDLLRKLLEKEGIDTDGIV-DEGRPTTTktrVIARnqqllrvdreddspL 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  89 DDHGERSFTFMVR---PSADLFLepadLPSFSAGewlhVCSIALSAEPSRSAafqamtsiREAGGYVSFDPnirpdlwad 165
Cdd:cd01172   117 SAEEEQRLIERIAerlPEADVVI----LSDYGKG----VLTPRVIEALIAAA--------RELGIPVLVDP--------- 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 166 enelrRCLELAL-QHADVVKLSVEELTFLTH-----DAQVKTGLESLMRRCPARLVLVTLGKEGVIAW-HDGAVKHYPAT 238
Cdd:cd01172   172 -----KGRDYSKyRGATLLTPNEKEAREALGdeindDDELEAAGEKLLELLNLEALLVTLGEEGMTLFeRDGEVQHIPAL 246
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1736704024 239 SVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALA 280
Cdd:cd01172   247 AKEVYDVTGAGDTVIATLALALAAGADLEEAAFLANAAAGVV 288
YegV_kinase_like cd01944
YegV-like sugar kinase. Found only in bacteria, YegV-like kinase is part of the ribokinase ...
3-285 3.46e-16

YegV-like sugar kinase. Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238919 [Multi-domain]  Cd Length: 289  Bit Score: 77.08  E-value: 3.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDL------LP----DGEGRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQ 72
Cdd:cd01944     1 KVLVIGAAVVDIvldvdkLPasggDIEAKSKSYVIGGGFNVMVAASRLGIPTVNAGPLGNGNWADQIRQAMRDEGIEILL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  73 MRLdPAHRTSTVVVDLDDHGERSFTFMVRPSADLFLEPADLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYV 152
Cdd:cd01944    81 PPR-GGDDGGCLVALVEPDGERSFISISGAEQDWSTEWFATLTVAPYDYVYLSGYTLASENASKVILLEWLEALPAGTTL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 153 SFDPNIRPDLwADENELRRCLELALqhadVVKLSVEELTFLT---HDAQVKTGLESLMRRcpARLVLVTLGKEGviAW-- 227
Cdd:cd01944   160 VFDPGPRISD-IPDTILQALMAKRP----IWSCNREEAAIFAergDPAAEASALRIYAKT--AAPVVVRLGSNG--AWir 230
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1736704024 228 -HDGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKG 285
Cdd:cd01944   231 lPDGNTHIIPGFKVKAVDTIGAGDTHAGGMLAGLAKGMSLADAVLLANAAAAIVVTRSG 289
FruK_PfkB_like cd01164
1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. ...
26-285 2.74e-15

1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.


Pssm-ID: 238570 [Multi-domain]  Cd Length: 289  Bit Score: 74.49  E-value: 2.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPANVAVGVARLGGNSAFIGRVGDDpFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHgersfTFM-VRPSA 104
Cdd:cd01164    35 AGGKGINVARVLKDLGVEVTALGFLGGF-TGDFFEALLKEEGIPDDFVEVAGETRINVKIKEEDGT-----ETEiNEPGP 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 105 DLflEPADLPSF--------SAGEWLHVC-SIALSAEPSrsaAFQAMTSI-REAGGYVSFDpnirpdlwADENELRRCLE 174
Cdd:cd01164   109 EI--SEEELEALleklkallKKGDIVVLSgSLPPGVPAD---FYAELVRLaREKGARVILD--------TSGEALLAALA 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 175 lalQHADVVKLSVEEL------TFLTHDAQVKTGLEslMRRCPARLVLVTLGKEGVIAWHDGAVKHYPATSVECVDTTGA 248
Cdd:cd01164   176 ---AKPFLIKPNREELeelfgrPLGDEEDVIAAARK--LIERGAENVLVSLGADGALLVTKDGVYRASPPKVKVVSTVGA 250
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1736704024 249 GDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKG 285
Cdd:cd01164   251 GDSMVAGFVAGLAQGLSLEEALRLAVAAGSATAFSPG 287
1-PFK TIGR03168
hexose kinase, 1-phosphofructokinase family; This family consists largely of ...
25-296 1.67e-14

hexose kinase, 1-phosphofructokinase family; This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.


Pssm-ID: 274464 [Multi-domain]  Cd Length: 303  Bit Score: 72.22  E-value: 1.67e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  25 CPGGAPANVAVGVARLGGNSAFIGRVGDDPfGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDdhgERSFTFMV---- 100
Cdd:TIGR03168  33 DAGGKGINVARVLARLGAEVVATGFLGGFT-GEFIEALLAEEGIKNDFVEVKGETRINVKIKESS---GEETELNEpgpe 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 101 --RPSADLFLE--PADLPSfsaGEWLhvcSIALSAEPSRSAAF--QAMTSIREAGGYVSFDpnirpdlwADENELRRCLE 174
Cdd:TIGR03168 109 isEEELEQLLEklRELLAS---GDIV---VISGSLPPGVPPDFyaQLIAIARKKGAKVILD--------TSGEALREALA 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 175 lalQHADVVKLSVEELTFLTH-----DAQVKTGLESLMRRcPARLVLVTLGKEGVIAWHDGAVKHYPATSVECVDTTGAG 249
Cdd:TIGR03168 175 ---AKPFLIKPNHEELEELFGrelktLEEIIEAARELLDR-GAENVLVSLGADGALLVTKEGALKATPPKVEVVNTVGAG 250
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1736704024 250 DAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGamTALPYHHEL 296
Cdd:TIGR03168 251 DSMVAGFLAGLARGLSLEEALRFAVAAGSAAAFSPG--TGLPDPEDV 295
PLN02548 PLN02548
adenosine kinase
26-266 4.76e-13

adenosine kinase


Pssm-ID: 178163 [Multi-domain]  Cd Length: 332  Bit Score: 68.20  E-value: 4.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPAN---VAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRlDPAHRTSTVVVDLDDhGERSF------ 96
Cdd:PLN02548   51 AGGATQNsirVAQWMLQIPGATSYMGCIGKDKFGEEMKKCATAAGVNVHYYE-DESTPTGTCAVLVVG-GERSLvanlsa 128
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  97 ------TFMVRPSADLFLEPADLpSFSAGEWLHVC--SIALSAEPSR----------SAAF-------QAMtsirEAGGY 151
Cdd:PLN02548  129 ancykvEHLKKPENWALVEKAKF-YYIAGFFLTVSpeSIMLVAEHAAannktfmmnlSAPFiceffkdQLM----EALPY 203
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 152 VSFdpnirpdLWADENElrrclelALQHADVVKLSVEELtflthdAQVKTGLESLMRRC--PARLVLVTLGKEGVIAWHD 229
Cdd:PLN02548  204 VDF-------LFGNETE-------ARTFAKVQGWETEDV------EEIALKISALPKASgtHKRTVVITQGADPTVVAED 263
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1736704024 230 GAVKHYPATSVE---CVDTTGAGDAFVAGLLYGLAAGQEL 266
Cdd:PLN02548  264 GKVKEFPVIPLPkekLVDTNGAGDAFVGGFLSQLVQGKDI 303
PLN02813 PLN02813
pfkB-type carbohydrate kinase family protein
20-286 1.65e-12

pfkB-type carbohydrate kinase family protein


Pssm-ID: 215434 [Multi-domain]  Cd Length: 426  Bit Score: 67.14  E-value: 1.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  20 GRLLQ----CP-----GGAPANVAVGVARLGGNS--------AFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHrTS 82
Cdd:PLN02813  110 GKVLRaldgCSykasaGGSLSNTLVALARLGSQSaagpalnvAMAGSVGSDPLGDFYRTKLRRANVHFLSQPVKDGT-TG 188
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  83 TVVVDLDDHGERSFTFMVRPSADLFLEPADLPSFSAGEWLHVCSIALSAEPSRSAAFQAMTSIREAGGYVSF---DPNI- 158
Cdd:PLN02813  189 TVIVLTTPDAQRTMLSYQGTSSTVNYDSCLASAISKSRVLVVEGYLWELPQTIEAIAQACEEAHRAGALVAVtasDVSCi 268
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 159 ---RPDLWadenelrrclELALQHADVVKLSVEELTFLTHDAQVKTGLES---LMRRCParLVLVTLGKEGVIAWHDGAV 232
Cdd:PLN02813  269 erhRDDFW----------DVMGNYADILFANSDEARALCGLGSEESPESAtryLSHFCP--LVSVTDGARGSYIGVKGEA 336
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1736704024 233 KHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIG-LAQRCGALATTAKGA 286
Cdd:PLN02813  337 VYIPPSPCVPVDTCGAGDAYAAGILYGLLRGVSDLRGMGeLAARVAATVVGQQGT 391
ribokinase_pfkB_like cd00287
ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including ...
133-261 1.82e-12

ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, 2-dehydro-3-deoxygluconokinase, 1-phosphofructokinase, the minor 6-phosphofructokinase (PfkB), inosine-guanosine kinase, and adenosine kinase. Even though there is a high degree of structural conservation within this superfamily, their multimerization level varies widely, monomeric (e.g. adenosine kinase), dimeric (e.g. ribokinase), and trimeric (e.g THZ kinase).


Pssm-ID: 238177 [Multi-domain]  Cd Length: 196  Bit Score: 64.81  E-value: 1.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 133 PSRSAAFQAMTSIREAGGYVSFDPNIRPDLWADENelrrcLELALQHADVVKLSVEELTFLTH----DAQVKTGLESLMR 208
Cdd:cd00287    68 PAPEAVLDALEEARRRGVPVVLDPGPRAVRLDGEE-----LEKLLPGVDILTPNEEEAEALTGrrdlEVKEAAEAAALLL 142
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1736704024 209 RCPARLVLVTLGKEGVIAWH-DGAVKHYPATSVECVDTTGAGDAFVAGLLYGLA 261
Cdd:cd00287   143 SKGPKVVIVTLGEKGAIVATrGGTEVHVPAFPVKVVDTTGAGDAFLAALAAGLA 196
pfkB TIGR03828
1-phosphofructokinase; This enzyme acts in concert with the fructose-specific ...
24-286 1.43e-11

1-phosphofructokinase; This enzyme acts in concert with the fructose-specific phosphotransferase system (PTS) which imports fructose as fructose-1-phosphate. The action of 1-phosphofructokinase results in beta-D-fructose-1,6-bisphosphate and is an entry point into glycolysis (GenProp0688).


Pssm-ID: 274804 [Multi-domain]  Cd Length: 304  Bit Score: 63.76  E-value: 1.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  24 QCPGGAPANVAVGVARLGGNSAFIGRVGDDPfGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDH-------Gersf 96
Cdd:TIGR03828  32 IDAGGKGINVSRVLKNLGVDVVALGFLGGFT-GDFIEALLREEGIKTDFVRVPGETRINVKIKEPSGTetklngpG---- 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  97 tFMVRPSA-DLFLE--PADLPsfsAGEWLhVCSIALSAEPSRSAAFQAMTSIREAGGYVSFDpnirpdlwADENELRRCL 173
Cdd:TIGR03828 107 -PEISEEElEALLEklRAQLA---EGDWL-VLSGSLPPGVPPDFYAELIALAREKGAKVILD--------TSGEALRDGL 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 174 ElalQHADVVKLSVEELTFLTHDAQvkTGLESL------MRRCPARLVLVTLGKEGVI------AWHDGAVKhypatsVE 241
Cdd:TIGR03828 174 K---AKPFLIKPNDEELEELFGREL--KTLEEIieaareLLDLGAENVLISLGADGALlvtkegALFAQPPK------GE 242
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1736704024 242 CVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALATTAKGA 286
Cdd:TIGR03828 243 VVSTVGAGDSMVAGFLAGLESGLSLEEALRLAVAAGSAAAFSEGT 287
PLN02379 PLN02379
pfkB-type carbohydrate kinase family protein
16-266 1.89e-11

pfkB-type carbohydrate kinase family protein


Pssm-ID: 178005 [Multi-domain]  Cd Length: 367  Bit Score: 63.66  E-value: 1.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  16 PDGEGRLLQCPGGAPANVAVGVAR-LGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHrTSTVVVDLDDHGER 94
Cdd:PLN02379   75 PDDLSPIKTMAGGSVANTIRGLSAgFGVSTGIIGACGDDEQGKLFVSNMGFSGVDLSRLRAKKGP-TAQCVCLVDALGNR 153
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  95 S----FTFMVRPSADLFLEPadlpSFSAGEWLHVCSIALSAEPSRSAAFQAmtsiREAGGYVSFD-------PNIRPdlw 163
Cdd:PLN02379  154 TmrpcLSSAVKLQADELTKE----DFKGSKWLVLRYGFYNLEVIEAAIRLA----KQEGLSVSLDlasfemvRNFRS--- 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 164 adenELRRCLE-----LALQHADvvklSVEELTFLTHDAQVKTGLESLMRRCpaRLVLVTLGKEGVIAWHDGAVKHYPAT 238
Cdd:PLN02379  223 ----PLLQLLEsgkidLCFANED----EARELLRGEQESDPEAALEFLAKYC--NWAVVTLGSKGCIARHGKEVVRVPAI 292
                         250       260
                  ....*....|....*....|....*....
gi 1736704024 239 -SVECVDTTGAGDAFVAGLLYGLAAGQEL 266
Cdd:PLN02379  293 gETNAVDATGAGDLFASGFLYGLIKGLSL 321
YeiC_kinase_like cd01941
YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ...
3-280 6.47e-11

YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238916 [Multi-domain]  Cd Length: 288  Bit Score: 61.56  E-value: 6.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024   3 KIWVLGDAVVDL-------LPDGE---GRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQilADEQVEVQq 72
Cdd:cd01941     1 EIVVIGAANIDLrgkvsgsLVPGTsnpGHVKQSPGGVGRNIAENLARLGVSVALLSAVGDDSEGESILE--ESEKAGLN- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  73 MR--LDPAHRTSTVVVDLDDHGE-------------------RSFTFMVRpSADLFLEPADLPSFSAGEWLHVC---SIA 128
Cdd:cd01941    78 VRgiVFEGRSTASYTAILDKDGDlvvaladmdiyelltpdflRKIREALK-EAKPIVVDANLPEEALEYLLALAakhGVP 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 129 LSAEPSRSAAFQAMTSIREAGGYVSfdPNirpdlwadENELRRCLELAlqHADVVKLSVEELTFLTHdaqvktGLESLMR 208
Cdd:cd01941   157 VAFEPTSAPKLKKLFYLLHAIDLLT--PN--------RAELEALAGAL--IENNEDENKAAKILLLP------GIKNVIV 218
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1736704024 209 RCPARLVLVTLGKEGVIAWHdgavkhYPA-TSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALA 280
Cdd:cd01941   219 TLGAKGVLLSSREGGVETKL------FPApQPETVVNVTGAGDAFVAGLVAGLLEGMSLDDSLRFAQAAAALT 285
PTZ00247 PTZ00247
adenosine kinase; Provisional
26-267 1.19e-07

adenosine kinase; Provisional


Pssm-ID: 240328 [Multi-domain]  Cd Length: 345  Bit Score: 52.34  E-value: 1.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGAPANVAvGVAR-----LGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPA----------HRTSTVVVDLDD 90
Cdd:PTZ00247   61 PGGSALNTA-RVAQwmlqaPKGFVCYVGCVGDDRFAEILKEAAEKDGVEMLFEYTTKAptgtcavlvcGKERSLVANLGA 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  91 HGERSFTFMVRPSADLFLEPADLpSFSAGEWLHVcsialSAEPSRSAAFQAmtsiREAGGYVSFD---PNIRPDLWadeN 167
Cdd:PTZ00247  140 ANHLSAEHMQSHAVQEAIKTAQL-YYLEGFFLTV-----SPNNVLQVAKHA----RESGKLFCLNlsaPFISQFFF---E 206
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 168 ELRrcleLALQHADVVKLSVEEL-TFLTHDAQVKTGLESLMRRCPA---------RLVLVTLGKEGVIAWHDGAVKHYPA 237
Cdd:PTZ00247  207 RLL----QVLPYVDILFGNEEEAkTFAKAMKWDTEDLKEIAARIAMlpkysgtrpRLVVFTQGPEPTLIATKDGVTSVPV 282
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1736704024 238 TSV---ECVDTTGAGDAFVAGLLYGLAAGQELV 267
Cdd:PTZ00247  283 PPLdqeKIVDTNGAGDAFVGGFLAQYANGKDID 315
PRK09850 PRK09850
pseudouridine kinase; Provisional
20-280 3.90e-07

pseudouridine kinase; Provisional


Pssm-ID: 182111 [Multi-domain]  Cd Length: 313  Bit Score: 50.76  E-value: 3.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  20 GRLLQCPGGAPANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLDPAHRTSTVVVDLDDHGE-----R 94
Cdd:PRK09850   33 GKIKFTPGGVGRNIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEmlvaiN 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  95 SFTFMVRPSADLFLEPADlpsFSAGEWLHVCSIALSAEpsrsaafqAMTSIREAGGYVSfdpnirpdLWADENELRRCLE 174
Cdd:PRK09850  113 DMNISNAITAEYLAQHRE---FIQRAKVIVADCNISEE--------ALAWILDNAANVP--------VFVDPVSAWKCVK 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 175 LALQHADVVKLSVEELTFLTHDAQVKTGLESLMRRCP-------ARLVLvTLGKEGV-IAWHDGAVKHYPATSVECVDTT 246
Cdd:PRK09850  174 VRDRLNQIHTLKPNRLEAETLSGIALSGREDVAKVAAwfhqhglNRLVL-SMGGDGVyYSDISGESGWSAPIKTNVINVT 252
                         250       260       270
                  ....*....|....*....|....*....|....
gi 1736704024 247 GAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALA 280
Cdd:PRK09850  253 GAGDAMMAGLASCWVDGMPFAESVRFAQGCSSMA 286
PRK11316 PRK11316
bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose ...
26-285 1.32e-05

bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE;


Pssm-ID: 183085 [Multi-domain]  Cd Length: 473  Bit Score: 46.36  E-value: 1.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  26 PGGApANVAVGVARLGGNSAFIGRVGDDPFGRFMYQILADEQVEVQQMRLdPAHRTST-----------VVVDLDDhger 94
Cdd:PRK11316   50 PGGA-ANVAMNIASLGAQARLVGLTGIDEAARALSKLLAAVGVKCDFVSV-PTHPTITklrvlsrnqqlIRLDFEE---- 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024  95 sfTFMVRPSADLF--LEPAdLPSFSAgewlhvcsIALS-------AEPsrsaafQAMTSI-REAGGYVSFDPN------- 157
Cdd:PRK11316  124 --GFEGVDPQPLLerIEQA-LPSIGA--------LVLSdyakgalASV------QAMIQLaRKAGVPVLIDPKgtdfery 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 158 -----IRPDL---------WADENELrrclelalqhadvvklsveeltflthdaqVKTGLEsLMRRCPARLVLVTLGKEG 223
Cdd:PRK11316  187 rgatlLTPNLsefeavvgkCKDEAEL-----------------------------VEKGMK-LIADYDLSALLVTRSEQG 236
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1736704024 224 V-IAWHDGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQElvpvigLAQRCgALATTAKG 285
Cdd:PRK11316  237 MtLLQPGKAPLHLPTQAREVYDVTGAGDTVISVLAAALAAGNS------LEEAC-ALANAAAG 292
fruK PRK09513
1-phosphofructokinase; Provisional
215-280 1.46e-05

1-phosphofructokinase; Provisional


Pssm-ID: 181923 [Multi-domain]  Cd Length: 312  Bit Score: 45.84  E-value: 1.46e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1736704024 215 VLVTLGKEGVIAWHDGAVKHYPATSVECVDTTGAGDAFVAGLLYGLAAGQELVPVIGLAQRCGALA 280
Cdd:PRK09513  220 VVISLGAEGALWVNASGEWIAKPPACDVVSTVGAGDSMVGGLIYGLLMRESSEHTLRLATAVSALA 285
Ketohexokinase cd01939
Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to ...
166-289 4.87e-05

Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes where it is believed to function as a dimer and requires K(+) and ATP to be active. In humans, hepatic KHK deficiency causes fructosuria, a benign inborn error of metabolism.


Pssm-ID: 238914 [Multi-domain]  Cd Length: 290  Bit Score: 43.93  E-value: 4.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 166 ENELRRCLELAlQHADVVKLSveeLTFLTHDAQvKTGLESLMRRCP----ARLVLVTLGKEGVIAWH-DGAVKHYPATSV 240
Cdd:cd01939   167 EKPREELLELA-AYCDVVFVS---KDWAQSRGY-KSPEECLRGEGPrakkAALLVCTWGDQGAGALGpDGEYVHSPAHKP 241
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1736704024 241 E-CVDTTGAGDAFVAGLLYGLAAGQELVPViglAQRCGALATTAKGAMTA 289
Cdd:cd01939   242 IrVVDTLGAGDTFNAAVIYALNKGPDDLSE---ALDFGNRVASQKCTGVG 288
PLN02630 PLN02630
pfkB-type carbohydrate kinase family protein
182-263 2.63e-04

pfkB-type carbohydrate kinase family protein


Pssm-ID: 178237  Cd Length: 335  Bit Score: 42.10  E-value: 2.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 182 VVKLSVEELTFLThdaqvktgLESLMRRCparLVLVTLGKEGV-IAWHDGAVkHYPATSVECVDTTGAGDAFVAGLLYGL 260
Cdd:PLN02630  184 FLKASSEEALFID--------VEEVRQKC---CVIVTNGKKGCrIYWKDGEM-RVPPFPAIQVDPTGAGDSFLGGFVAGL 251

                  ...
gi 1736704024 261 AAG 263
Cdd:PLN02630  252 VQG 254
MAK32 cd01943
MAK32 kinase. MAK32 is a protein found primarily in fungi that is necessary for the ...
220-280 6.61e-04

MAK32 kinase. MAK32 is a protein found primarily in fungi that is necessary for the structural stability of L-A particles. The L-A virus particule is a specialized compartment for the transcription and replication of double-stranded RNA, known to infect yeast and other fungi. MAK32 is part of the host machinery used by the virus to multiply.


Pssm-ID: 238918 [Multi-domain]  Cd Length: 328  Bit Score: 40.79  E-value: 6.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1736704024 220 GKEG--VIAWHDGAVKHYPA--TSVECV-DTTGAGDAFVAGLLYGLAAGQELVPviglAQRCGALA 280
Cdd:cd01943   233 GKLGcyVGSADSGPELWLPAyhTKSTKVvDPTGGGNSFLGGFAAGLALTKSIDE----ACIYGSVA 294
ribokinase_group_C cd01946
Ribokinase-like subgroup C. Found only in bacteria, this subgroup is part of the ribokinase ...
177-276 3.01e-03

Ribokinase-like subgroup C. Found only in bacteria, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238921 [Multi-domain]  Cd Length: 277  Bit Score: 38.60  E-value: 3.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1736704024 177 LQHADVVKLSVEELTFLTHDAQ-VKTGleSLMRRCPARLVLVTLGKEGVIAWHDGAVKHYPATSVECV-DTTGAGDAFvA 254
Cdd:cd01946   161 LAKVDVVIINDGEARQLTGAANlVKAA--RLILAMGPKALIIKRGEYGALLFTDDGYFAAPAYPLESVfDPTGAGDTF-A 237
                          90       100
                  ....*....|....*....|..
gi 1736704024 255 GLLYGLAAGQELVPVIGLAQRC 276
Cdd:cd01946   238 GGFIGYLASQKDTSEANMRRAI 259
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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