|
Name |
Accession |
Description |
Interval |
E-value |
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
1-442 |
0e+00 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 816.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 1 MNMRFPTVITLPWRTDAAEFWFARLSHLPWAMLLHSGHADHPYSRFDIVVADPVRTVTSENQP-----------STHDPL 69
Cdd:PRK15465 1 MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVADPICTLTTFGKEtvvsesekrttTTDDPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 70 IQLQEAIDELGLSATPNPDIPFQGGALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVVSLLSHSDV 149
Cdd:PRK15465 81 QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRQTVSLLSHNDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 150 EARLAWLNAQQPAAAPDFRLTSAWRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAP 229
Cdd:PRK15465 161 NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 230 FSAFIRLDQGAILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVP 309
Cdd:PRK15465 241 FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 310 GSVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVC 389
Cdd:PRK15465 321 GSVKVPELFVVEPFPAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1747561502 390 GTLDTSITIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQLEN 442
Cdd:PRK15465 401 GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNRILRQLEK 453
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
3-441 |
0e+00 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 585.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 3 MRFPTVITLPWRTDAAEfWFARLSHLPWAMLLHSGHADHPYSRFDIVVADPVRTVTSEN-----------QPSTHDPLIQ 71
Cdd:COG0147 1 ARIPVYRELLALETPVS-LFLKLADGPYAFLLESAEGGEKWGRYSFIGADPLATLTVRGgrvtiegggevEPSEGDPLDA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 72 LQEAIDELglSATPNPDIP-FQGGALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVvsllshsdve 150
Cdd:COG0147 80 LRALLARF--RLPPLPGLPpFTGGLVGYFGYDLVRYFERLPDLAPDDLGLPDAALGLYDRLLVFDHLKGT---------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 151 arlawlnaqqpaaapdfrltsawRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPF 230
Cdd:COG0147 148 -----------------------RSNFTREEYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEGDPLALYRALRRINPSPY 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 231 SAFIRLDQGAILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPG 310
Cdd:COG0147 205 MFYLRFGDFAIVGSSPERLVRVEDGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPG 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 311 SVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCG 390
Cdd:COG0147 285 SVKVPELMVVERYSHVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDG 364
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1747561502 391 TLDTSITIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQLE 441
Cdd:COG0147 365 NMDLAIAIRTAVVKDGRAYVQAGAGIVADSDPEAEYQETLNKARALLRALE 415
|
|
| pabB |
TIGR00553 |
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, ... |
95-436 |
1.12e-154 |
|
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, aminodeoxychorismate synthase, component I (PabB), were designated para-aminobenzoate synthase component I until it was recognized that PabC, a lyase, completes the pathway of PABA synthesis. This family is closely related to anthranilate synthase component I (trpE), and both act on chorismate. The clade of PabB enzymes represented by this model includes sequences from Gram-positive and alpha and gamma Proteobacteria as well as Chlorobium, Nostoc, Fusobacterium and Arabidopsis. A closely related clade of fungal PabB enzymes is identified by TIGR01823, while another bacterial clade of potential PabB enzymes is more closely related to TrpE (TIGR01824). [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid]
Pssm-ID: 273133 Cd Length: 328 Bit Score: 441.05 E-value: 1.12e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 95 ALGVFGYDLGrrfetlpsvakadiplPDMAVGLYDWALIVDHHKQ-VVSLLSHSDVEAR-LAWLNAQQPAAAPDFRLTSA 172
Cdd:TIGR00553 1 LVGYLSYEAG----------------PDAAFEPYDAALLADHRRTpLLRFLVFERVEAQpRAAVEAEDDAPADRQAPTSD 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 173 WRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPERFIHL 252
Cdd:TIGR00553 65 IQSEMTRAEYGEAIDQLQDYIRAGDCYQANLTQQFHATWDGDPLAAFRKLRRRQPAPFSAFLDLGDGAILSLSPELFFSI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 253 AEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVST 332
Cdd:TIGR00553 145 DGSEIETRPIKGTLPRGADPQEDRAQASALAESAKDRAENLMIVDLLRNDLGRIAEVGSVKVPELFVVETYPTVHQLVST 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 333 ITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSA 412
Cdd:TIGR00553 225 ITARLREDLTLSDLFRALFPGGSITGAPKVRAMEIIDELEPQPRGVYCGAIGYLSPEGDMDFNVAIRTLTLDGGRAVYGV 304
|
330 340
....*....|....*....|....
gi 1747561502 413 GGGIVADSQVEAEYQETFDKVNRI 436
Cdd:TIGR00553 305 GGGIVADSDPEAEYRECLLKAAPL 328
|
|
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
180-432 |
3.98e-119 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 348.00 E-value: 3.98e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 180 QTYAEKFARVQAYLQSGDCYQVNLAQRFQAT--YQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPERFIHLAEGKI 257
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPlaGDIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVDGGRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 258 QTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQL 337
Cdd:pfam00425 81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 338 PASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSAGGGIV 417
Cdd:pfam00425 161 KPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240
|
250
....*....|....*
gi 1747561502 418 ADSQVEAEYQETFDK 432
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
1-442 |
0e+00 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 816.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 1 MNMRFPTVITLPWRTDAAEFWFARLSHLPWAMLLHSGHADHPYSRFDIVVADPVRTVTSENQP-----------STHDPL 69
Cdd:PRK15465 1 MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVADPICTLTTFGKEtvvsesekrttTTDDPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 70 IQLQEAIDELGLSATPNPDIPFQGGALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVVSLLSHSDV 149
Cdd:PRK15465 81 QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRQTVSLLSHNDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 150 EARLAWLNAQQPAAAPDFRLTSAWRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAP 229
Cdd:PRK15465 161 NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 230 FSAFIRLDQGAILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVP 309
Cdd:PRK15465 241 FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 310 GSVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVC 389
Cdd:PRK15465 321 GSVKVPELFVVEPFPAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1747561502 390 GTLDTSITIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQLEN 442
Cdd:PRK15465 401 GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNRILRQLEK 453
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
3-441 |
0e+00 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 585.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 3 MRFPTVITLPWRTDAAEfWFARLSHLPWAMLLHSGHADHPYSRFDIVVADPVRTVTSEN-----------QPSTHDPLIQ 71
Cdd:COG0147 1 ARIPVYRELLALETPVS-LFLKLADGPYAFLLESAEGGEKWGRYSFIGADPLATLTVRGgrvtiegggevEPSEGDPLDA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 72 LQEAIDELglSATPNPDIP-FQGGALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVvsllshsdve 150
Cdd:COG0147 80 LRALLARF--RLPPLPGLPpFTGGLVGYFGYDLVRYFERLPDLAPDDLGLPDAALGLYDRLLVFDHLKGT---------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 151 arlawlnaqqpaaapdfrltsawRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPF 230
Cdd:COG0147 148 -----------------------RSNFTREEYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEGDPLALYRALRRINPSPY 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 231 SAFIRLDQGAILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPG 310
Cdd:COG0147 205 MFYLRFGDFAIVGSSPERLVRVEDGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPG 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 311 SVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCG 390
Cdd:COG0147 285 SVKVPELMVVERYSHVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDG 364
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1747561502 391 TLDTSITIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQLE 441
Cdd:COG0147 365 NMDLAIAIRTAVVKDGRAYVQAGAGIVADSDPEAEYQETLNKARALLRALE 415
|
|
| pabB |
TIGR00553 |
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, ... |
95-436 |
1.12e-154 |
|
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, aminodeoxychorismate synthase, component I (PabB), were designated para-aminobenzoate synthase component I until it was recognized that PabC, a lyase, completes the pathway of PABA synthesis. This family is closely related to anthranilate synthase component I (trpE), and both act on chorismate. The clade of PabB enzymes represented by this model includes sequences from Gram-positive and alpha and gamma Proteobacteria as well as Chlorobium, Nostoc, Fusobacterium and Arabidopsis. A closely related clade of fungal PabB enzymes is identified by TIGR01823, while another bacterial clade of potential PabB enzymes is more closely related to TrpE (TIGR01824). [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid]
Pssm-ID: 273133 Cd Length: 328 Bit Score: 441.05 E-value: 1.12e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 95 ALGVFGYDLGrrfetlpsvakadiplPDMAVGLYDWALIVDHHKQ-VVSLLSHSDVEAR-LAWLNAQQPAAAPDFRLTSA 172
Cdd:TIGR00553 1 LVGYLSYEAG----------------PDAAFEPYDAALLADHRRTpLLRFLVFERVEAQpRAAVEAEDDAPADRQAPTSD 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 173 WRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPERFIHL 252
Cdd:TIGR00553 65 IQSEMTRAEYGEAIDQLQDYIRAGDCYQANLTQQFHATWDGDPLAAFRKLRRRQPAPFSAFLDLGDGAILSLSPELFFSI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 253 AEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVST 332
Cdd:TIGR00553 145 DGSEIETRPIKGTLPRGADPQEDRAQASALAESAKDRAENLMIVDLLRNDLGRIAEVGSVKVPELFVVETYPTVHQLVST 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 333 ITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSA 412
Cdd:TIGR00553 225 ITARLREDLTLSDLFRALFPGGSITGAPKVRAMEIIDELEPQPRGVYCGAIGYLSPEGDMDFNVAIRTLTLDGGRAVYGV 304
|
330 340
....*....|....*....|....
gi 1747561502 413 GGGIVADSQVEAEYQETFDKVNRI 436
Cdd:TIGR00553 305 GGGIVADSDPEAEYRECLLKAAPL 328
|
|
| PabB-clade2 |
TIGR01824 |
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely ... |
93-432 |
2.64e-124 |
|
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.
Pssm-ID: 130883 Cd Length: 355 Bit Score: 364.86 E-value: 2.64e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 93 GGALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVVsLLSHSDVEA---------RLAWLNAQQPAA 163
Cdd:TIGR01824 1 GGRLGWLAYDVARRLEGIPDLGTSDGGWPVAADFRYEAAVARDHQRQIV-ALATVPAETegefatssdQLPAVAAATSLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 164 APDFRLTSAWRSNMTPQ-TYAEKFARVQAYLQSGDCYQVNLAQRFQA--TYQGDEWQAFTRLNASNRAPFSAFIRLDQGA 240
Cdd:TIGR01824 80 SPDVGPLPVDLEASIDRaAYETGVRRIKDYIRAGDVFQANLSRRLTApiAADVDPLQLFLALRAPNPAPYAIYLEEPGVD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 241 ILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVV 320
Cdd:TIGR01824 160 VASASPELFLAREGRVVQTRPIAGTRPRGATLAEDGALAAELLQHDKDRAEHVMIVDLERNDLGRVCATGTVRVPELCAV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 321 EPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRT 400
Cdd:TIGR01824 240 ESYSHVHHLVSRVTGRLREGAGLADLIRALFPGGSITGAPKVRAMEIIDELEPQPRGPYTGSVGWIDADGNADLNILIRT 319
|
330 340 350
....*....|....*....|....*....|..
gi 1747561502 401 LTACDGQLYCSAGGGIVADSQVEAEYQETFDK 432
Cdd:TIGR01824 320 LEGGGAQLHFRTGAGIVADSDPAGEWDETEAK 351
|
|
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
180-432 |
3.98e-119 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 348.00 E-value: 3.98e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 180 QTYAEKFARVQAYLQSGDCYQVNLAQRFQAT--YQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPERFIHLAEGKI 257
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPlaGDIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVDGGRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 258 QTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQL 337
Cdd:pfam00425 81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 338 PASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSAGGGIV 417
Cdd:pfam00425 161 KPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240
|
250
....*....|....*
gi 1747561502 418 ADSQVEAEYQETFDK 432
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
|
|
| trpE_most |
TIGR00564 |
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some ... |
33-432 |
1.93e-116 |
|
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. Archaeal enzymes have been excluded from this model (and are now found in TIGR01820) as have a clade of enzymes which constitute a TrpE paralog which may have PabB activity (TIGR01824). This allows the B. subtilus paralog which has been shown to have PabB activity to score below trusted to this model. This model contains sequences from gram-positive bacteria, certain proteobacteria, cyanobacteria, plants, fungi and assorted other bacteria.A second family of TrpE enzymes is modelled by TIGR00565. The breaking of the TrpE family into these diverse models allows for the separation of the models for the related enzyme, PabB. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273142 [Multi-domain] Cd Length: 454 Bit Score: 348.17 E-value: 1.93e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 33 LLHSGHADHPYSRFDIVVADPVRTVTSENQPSTH-----------DPLIQLQEAIDELGLSATPNPDIPFQGGALGVFGY 101
Cdd:TIGR00564 20 LLESAEPGSERGRYSFIGLNPVLTIKTEGGTEYLgaddrrsgivgNPLDEIRDVMETFAQHSDPELPIPFTGGAVGYLGY 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 102 DLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVVSLLSH-----------------SDVEARLAWLNAQ----Q 160
Cdd:TIGR00564 100 DTVRLFEKITLPPPDPLNLPDAYLMLCDDFIIFDHVTDKLYLIHNnrttasrsakaaadarlEALVADLQDPLLPevpvP 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 161 PAAAPDFRltsawrSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGA 240
Cdd:TIGR00564 180 YPAALSFT------SNYEKEEYEANVAKAKEYIKAGDIFQVVLSQRFEAKTEAPPFELYRVLRIVNPSPYMYYLDFGDFQ 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 241 ILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVV 320
Cdd:TIGR00564 254 IVGSSPELLVKVTGGRITTRPIAGTRKRGATPEEDEALAEELLADEKERAEHLMLVDLGRNDIGRVCEPGSVEVPEFMKI 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 321 EPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRT 400
Cdd:TIGR00564 334 ERYSHVMHIVSTVEGRLKDGLTAIDALRATFPAGTVSGAPKIRAMELIDELEPEKRGIYGGAVGYLSFDGDMDTAIAIRT 413
|
410 420 430
....*....|....*....|....*....|..
gi 1747561502 401 LTACDGQLYCSAGGGIVADSQVEAEYQETFDK 432
Cdd:TIGR00564 414 MVVKDGKAYVQAGGGIVADSDPEAEYEETLNK 445
|
|
| PRK05940 |
PRK05940 |
anthranilate synthase component I; |
22-441 |
8.62e-102 |
|
anthranilate synthase component I;
Pssm-ID: 235651 [Multi-domain] Cd Length: 463 Bit Score: 311.28 E-value: 8.62e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 22 FARL-SHLPWAMLLHS---GHADHPY-SRFDIVVADPVRTVTSENQPSTHDPLIQ--LQEAIDelgLSATPnPDIPFQGG 94
Cdd:PRK05940 24 FERLfGQQGIATLLESpypTPADYPPlSRYSICAGSPRKPRLWTPKLGEILPFLRqlLARSLD---PSALP-EHLPFTGG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 95 ALGVFGYDLGRRFETLPSVaKADiPLPDMAVGLYDWA--LIVDHHKQVVsLLSHSDVEaRLAWLNAQ--QPAAAPDFRLT 170
Cdd:PRK05940 100 WLGWLGYDLAWEIERLPHL-NPD-PLPFPVAYWYEPEsfAILDHQEQIL-WLAASDPS-QLDRLEQQleQPTPEPDLPLD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 171 -----SAWRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLS 245
Cdd:PRK05940 176 lrtppSSLIFYTTQQEYEAAVRQAKKYIQAGDIFQANLSLRFQTTTSADSWQIYRRLQQINPSPFASYWRTPWGDVVSCS 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 246 PERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPA 325
Cdd:PRK05940 256 PERLVQLQGNQAQTRPIAGTRPRGKTPAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQWGSVEVDELLTIERYSH 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 326 VHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTL---- 401
Cdd:PRK05940 336 VIHLVSNVVGTLQPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLDLNILIRTLlytp 415
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1747561502 402 -TACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQLE 441
Cdd:PRK05940 416 lSRGLSTIWGQVGAGIVADSDPEKEWLESLQKAKAQLAALN 456
|
|
| PRK09070 |
PRK09070 |
aminodeoxychorismate synthase component I; |
33-441 |
2.68e-100 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236371 [Multi-domain] Cd Length: 447 Bit Score: 306.63 E-value: 2.68e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 33 LLHSGHADHPYSRFDIVVADPVRTVTSENQPSTHDP-----LIQLQEAIDELGLSATPNPDIPFQGGALGVFGYDLGRRF 107
Cdd:PRK09070 27 LLESSASGTAQGRWDVLLLAQGKCLRLDPDGVTRQLlegdfLDALDAAWQAERVPHDGESSLPFRGGWAVLLDYELAGQV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 108 E-TLPSVAKADiPLPDMAVGLYDWALIVDHHKQVVSLLSHSDVEARLAWLNAQQpAAAPDFRLTSAWRSNMT-----PQT 181
Cdd:PRK09070 107 EpILKLPMRTD-GLPLALALRAPAAVLRDRHSGRCVLVAEPGREHLLDQIEADL-AACAALPPLPVWLAPQAveedpPER 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 182 YAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQA--FTRLNASNRAPFSAFIRLDQGAILSLSPERFIHLAEGKIQT 259
Cdd:PRK09070 185 FTDGVERVLDYIRAGDVFQVNLSRAWQAQFANAVDPAalYARLRAANPAPFSGLFVAAGRAIVSSSPERLVSVQGGVVQT 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 260 RPIKGTLPRlSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLPA 339
Cdd:PRK09070 265 RPIAGTRPR-FAGDDDAALIRELVGHPKERAEHVMLIDLERNDLGRICAPGSVEVDELMTVESYAHVHHIVSNVRGRLRD 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 340 SRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSAGGGIVAD 419
Cdd:PRK09070 344 GVTPGEVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGNQVRFRTGAGIVVD 423
|
410 420
....*....|....*....|..
gi 1747561502 420 SQVEAEYQETFDKVNRILQQLE 441
Cdd:PRK09070 424 SDPERELDETRAKARGLLRALE 445
|
|
| PRK07508 |
PRK07508 |
aminodeoxychorismate synthase component I; |
97-439 |
3.05e-100 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236035 [Multi-domain] Cd Length: 378 Bit Score: 304.24 E-value: 3.05e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 97 GVFGYDLGRRFET-LPSVAKADIPLPDMAVGLYDwALIVDHHKQVvsllSHSDVEARLAwlnaqQPAAAPDFrltsawrs 175
Cdd:PRK07508 50 GYLSYEAGYLLEPkLAPLMPEGRETPLLCFGVFD-APSPEAPAPA----RPSENAARLR-----DPVARWDF-------- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 176 nmtpQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPERFIHL-AE 254
Cdd:PRK07508 112 ----ADYAQRFERLHRHIRAGDCYQANLTFPLDARWGGDPLALFWALAARQPVGYGALVDLGGPVILSRSPELFFRVdGE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 255 GKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTIT 334
Cdd:PRK07508 188 GWIETHPMKGTAPRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDISRISEVGSLDVPELFDIETYPTVHQMVSRVR 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 335 AQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLT-ACDGQLYCSAG 413
Cdd:PRK07508 268 ARLLPGLGLADIFAALFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWIAPDGRMRFNVAIRTLSlFPGGRAVFNVG 347
|
330 340
....*....|....*....|....*.
gi 1747561502 414 GGIVADSQVEAEYQETFDKVnRILQQ 439
Cdd:PRK07508 348 GGIVFDSTAEAEYEECLLKA-RFAVG 372
|
|
| PRK13571 |
PRK13571 |
anthranilate synthase component I; Provisional |
63-432 |
2.41e-96 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184152 [Multi-domain] Cd Length: 506 Bit Score: 298.47 E-value: 2.41e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 63 PSTHDPLIQLQEAIDELglsATPN-PDIP-FQGGALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQV 140
Cdd:PRK13571 94 PTGGDPLAALRATLELL---ATPRlPGLPpLTGGMVGFLGYDAVRRLERLPELAVDDLGLPEMLLLLATDLAAVDHHEGT 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 141 VSL----LSHSDVEARL--AWLNAQ-----------QPAAAPDFRLTSA---WRSNMTPQTYAEKFARVQAYLQSGDCYQ 200
Cdd:PRK13571 171 ITLianaVNWNGTDERVdaAYDDAVarldvmtaalaQPLPSTVATFSRPvpeFRAQRTVEEFGAAVEKLVEEIRAGEAFQ 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 201 VNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGA------ILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAA 274
Cdd:PRK13571 251 VVPSQRFEMDTTADPLDVYRVLRVTNPSPYMYLLRVPNSDggtdfsIVGSSPEALVTVTDGRATTHPIAGTRWRGATPEE 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 275 DRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGG 354
Cdd:PRK13571 331 DALLEKELLADPKERAEHLMLVDLGRNDLGRVCRPGTVRVVDFSHIERYSHVMHLVSTVTGELAEGRTALDAVTACFPAG 410
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1747561502 355 SITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDK 432
Cdd:PRK13571 411 TLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIAIRTALMRDGTAYVQAGGGVVADSDPDYEDNEARNK 488
|
|
| PLN02445 |
PLN02445 |
anthranilate synthase component I |
75-432 |
2.19e-77 |
|
anthranilate synthase component I
Pssm-ID: 215244 [Multi-domain] Cd Length: 523 Bit Score: 249.98 E-value: 2.19e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 75 AIDELglsatpnPDIpFQGGALGVFGYDLGRRFET--LP--SVAKADIPLPDMAVGLYDWALIVDH-HKQV-----VSLL 144
Cdd:PLN02445 110 LIDGL-------PDV-FCGGWVGYFSYDTVRYVEKkkLPfsGAPEDDRNLPDIHLGLYDDVIVFDHvEKKAyvihwVRLD 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 145 SHSDVEA-------RLAWLNAQ-QPAAAPDF-----------RLTSAWRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQ 205
Cdd:PLN02445 182 RYSSVEEayedgmkRLEALVSRlQDINPPKLspgsvklstnqFGPSLEKSNMTSEEYKNAVLQAKEHILAGDIFQIVLSQ 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 206 RFQATYQGDEWQAFTRLNASNRAPFSAFIRLdQGAIL-SLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAA 284
Cdd:PLN02445 262 RFERRTFADPFEVYRALRIVNPSPYMIYLQA-RGCILvASSPEILTRVKKNKIVNRPLAGTRRRGKTPEEDKALEKDLLA 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 285 SPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRA 364
Cdd:PLN02445 341 DEKQCAEHIMLVDLGRNDVGKVSKAGSVKVEKLMNIERYSHVMHISSTVTGELLDHLTSWDALRAALPVGTVSGAPKVRA 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 365 MEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTL---TAC---------DGQL------YCSAGGGIVADSQVEAEY 426
Cdd:PLN02445 421 MELIDELEVTRRGPYSGGFGGVSFTGDMDIALALRTMvfpTAArydtmysykDTNSrrewvaHLQAGAGIVADSDPEDEY 500
|
....*.
gi 1747561502 427 QETFDK 432
Cdd:PLN02445 501 RECVNK 506
|
|
| PRK05877 |
PRK05877 |
aminodeoxychorismate synthase component I; Provisional |
163-442 |
2.99e-76 |
|
aminodeoxychorismate synthase component I; Provisional
Pssm-ID: 235634 [Multi-domain] Cd Length: 405 Bit Score: 243.46 E-value: 2.99e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 163 AAPDFRLTSAWRSNMTPQTYAEKFARVQAYLQS---GDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQG 239
Cdd:PRK05877 122 ATTRARPAPPCRIDWTPPDRAAHRDGVLACLEAiaaGEVYQACVCTQFTGTVTGSPLDFFADGVARTAPARAAYLAGDWG 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 240 AILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAAdrqqaekLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFV 319
Cdd:PRK05877 202 AVASLSPELFLRRRGSVVTSSPIKGTLPLDADPSA-------LRASAKDVAENIMIVDLVRNDLGRVARTGTVTVPELLV 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 320 VEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIR 399
Cdd:PRK05877 275 VRPAPGVWHLVSTVSAQVPDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGCELNVAIR 354
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1747561502 400 TLT-ACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQLEN 442
Cdd:PRK05877 355 TVEfDADGNAVLGVGGGITADSDPDAEWQECLHKAAPIVGLPAA 398
|
|
| PLN02889 |
PLN02889 |
oxo-acid-lyase/anthranilate synthase |
91-428 |
4.58e-70 |
|
oxo-acid-lyase/anthranilate synthase
Pssm-ID: 215481 [Multi-domain] Cd Length: 918 Bit Score: 238.59 E-value: 4.58e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 91 FQGGALGVFGYDLGRRFETLPSVAKADIPlpDMAVGLYDWALIVDHHKQVVSLLS-HSDVEARLAWLN------------ 157
Cdd:PLN02889 538 FHGGYVGYIGYDLKVECGMASNRHKSTTP--DACFFFADNVVVIDHHYDDVYILSlHEGSTATTQWLDdteqkllglkas 615
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 158 -----AQQPAAAPDFrltSAWRSNMTPQTYAEKFAR-VQA---YLQSGDCYQVNLAQRFQATY-QGDEWQAFTRLNASNR 227
Cdd:PLN02889 616 atrklEVQTSPTATF---SPSKAGFLADKSREQYIKdVQKclkYIKDGESYELCLTTQMRKRIgEIDSLGLYLHLREKNP 692
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 228 APFSAFIRL--DQGAILSLSPERFIHLAE-GKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIG 304
Cdd:PLN02889 693 APYAAWLNFsnENLCICSSSPERFLKLDRnGMLEAKPIKGTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLG 772
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 305 RVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIG 384
Cdd:PLN02889 773 RVCEPGSVHVPNLMDVESYTTVHTMVSTIRGKKRSNMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIG 852
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1747561502 385 YVSVCGTLDTSITIRTLTACDGQLYCSAGGGIVADSQVEAEYQE 428
Cdd:PLN02889 853 FFSYNQTFDLNIVIRTVVIHEGEASIGAGGAIVALSNPEDEYEE 896
|
|
| PRK13574 |
PRK13574 |
anthranilate synthase component I; Provisional |
31-433 |
9.49e-68 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184155 [Multi-domain] Cd Length: 420 Bit Score: 221.61 E-value: 9.49e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 31 AMLLHSGHADHPYSRFDIVVADPVRTVTSENqpsthDPLIQLQEAidelgLSATPNPDIP--FQGGALGVFGYDLGRRFE 108
Cdd:PRK13574 26 AGLLESIGGPQYKARYSVIAWGTNGYLKIHD-----DPVNILNSY-----LKDLKLVDIPglFKGGMIGYISYDAVRFWE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 109 TLPSVAKADIPLPDMAVGLYDWALIVDHHKQVVsllshsdvearlaWLNAQQPAAA-----PDFRLtSAWRSNMTPQTYA 183
Cdd:PRK13574 96 KIRDLKPAAEDWPYAEFFIPDNIIIYDHNEGKV-------------YVNGDLSSVGgcgdmGEFKI-SFYDESLNKNNYE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 184 EKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPERFIHLAEGKIQTRPIK 263
Cdd:PRK13574 162 KIVSESLEYIRSGYIFQVVLSRFYRYLFSGDPLRIYYNLRRINPSPYMFYLKFDERYLIGSSPELLFRVQDNIVETYPIA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 264 GTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLPASRTP 343
Cdd:PRK13574 242 GTRPRGSDQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVRVPELMYVEKYSHVQHIVSKVIGTLKKKYNA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 344 CDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSAGGGIVADSQVE 423
Cdd:PRK13574 322 LDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKDLLRIQAGAGIVYDSNPE 401
|
410
....*....|
gi 1747561502 424 AEYQETFDKV 433
Cdd:PRK13574 402 SEYFETEHKL 411
|
|
| PRK13572 |
PRK13572 |
anthranilate synthase component I; Provisional |
33-441 |
1.05e-67 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 237432 [Multi-domain] Cd Length: 435 Bit Score: 221.92 E-value: 1.05e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 33 LLHSGHADHPYSRFDIVVADPVRTVTSENQ--------PSTHDPLIQLQEAIDELglsatpNPDIPFQGGALGVFGYD-- 102
Cdd:PRK13572 26 ILESAEKGQRKARYTYISANPEFMVRIGNKtkvdgetiSKESNPFKALKENFKIT------QSGDRFTGGFVGYIAYDav 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 103 ---LGRRFETlPSVakadiplpdmaVGLYDWALIVDHHKQVVSLLSHSDVEARLawLNAQ---QPAAAPDFRL----TSA 172
Cdd:PRK13572 100 hnyIGGKIEE-PSV-----------FGYYDHVFVYDHVTRKFYFHSLNNNPEEL--FNAEkivEKAKRFEIEEedggSEV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 173 WRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQgAILSLSPERFIHL 252
Cdd:PRK13572 166 LGCDADREEFVEMVEKAKEYIYSGDVFQVVLSREYRLKTDLSPFQLYRNLREINPSPYMFLLEFDK-DVVGASPETMASV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 253 AEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVST 332
Cdd:PRK13572 245 ENNILKINPIAGTAPRGKTEEEDKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYSHVQHIESE 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 333 ITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRtLTACDGQLYCSA 412
Cdd:PRK13572 325 VVGELKEDSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIR-MAEIDKVCRVRA 403
|
410 420
....*....|....*....|....*....
gi 1747561502 413 GGGIVADSQVEAEYQETFDKVNRILQQLE 441
Cdd:PRK13572 404 GAGIVADSVPEKEFYETERKMAAVLKALG 432
|
|
| PRK13567 |
PRK13567 |
anthranilate synthase component I; Provisional |
32-438 |
2.50e-54 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184148 [Multi-domain] Cd Length: 468 Bit Score: 187.66 E-value: 2.50e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 32 MLLHSGHADHPYSRFDIVVADPVRTVT-----------SENQPSTHDPLIQLQEAIDELGLSATPN--PDIPFQGGALGV 98
Cdd:PRK13567 25 IILESTNQQQTKGRYSVVIFDIYGTLTldndvlsvstlKESYQITERPYHYLTTKINEDYHNIQDEqlKSLPFISGYVGT 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 99 FGYDLGRR-FETLPSVAKADIPLPDMAVGLYDWALIVDHHKQ--------VVSLLSHSDVEAR-------LAWLNAQQPA 162
Cdd:PRK13567 105 CSFDLVRHeFPKLQSIQLEDHKQHDVRLYMVEQVYVFDHYKDelyiiatnQFSNSTKSDLENRvnksiedLTKIQPFMPT 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 163 AAPDFRlTSAWRSNMTPQTYAEKFARVQAYLQSGDCYQV------NLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRL 236
Cdd:PRK13567 185 QDFDFK-TKEIQSNISEERFIEMIQYFKEKITEGDMFQVvpsriyKYAHHASQHLNQLSFQLYQNLKRQNPSPYMYYLNI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 237 DQGAILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPE 316
Cdd:PRK13567 264 DQPYIVGSSPESFVSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVSKIGTSKITK 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 317 LFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSI 396
Cdd:PRK13567 344 LMVIEKYEHVMHIVSEVTGKINQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQYPHKRGVYSGGVGYINCNHNLDFAL 423
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1747561502 397 TIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQ 438
Cdd:PRK13567 424 AIRTMMIDEQYINVEAGCGVVYDSIPEKELNETKLKAKSLLE 465
|
|
| PRK13564 |
PRK13564 |
anthranilate synthase component 1; |
62-432 |
3.72e-51 |
|
anthranilate synthase component 1;
Pssm-ID: 237428 [Multi-domain] Cd Length: 520 Bit Score: 180.41 E-value: 3.72e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 62 QPSTHDPLIQLQEAIDelglSATPNPDIPFQGGalgVFGYDLGRRFETLPSVAKADIpLPDMAVGLYDWALIVDHHKQVV 141
Cdd:PRK13564 120 SLSVFDALRLLQKLVN----TPKEEREALFLGG---LFAYDLVAGFEPLPQLPAGNN-CPDYCFYLAETLLVIDHQKKSA 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 142 SLLSHS---------DVEARLAWLNAQQPAAAPDFRLTSAwrSNMTPQT------YAEKFARVQAYLQSGDCYQVNLAQR 206
Cdd:PRK13564 192 RLQASLftpdeeekqRLAARLAQLKQQLTQPAPPLPVTSV--PDMEVSVnisdeeFCAVVRKLKEHIRAGDIFQVVPSRR 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 207 FQ-------ATYQgdewqaftRLNASNRAPFSAFIRlDQ-----GAilslSPE---RFIHlAEGKIQTRPIKGTLPRLSD 271
Cdd:PRK13564 270 FSlpcpsplAAYR--------VLKKSNPSPYMFYMQ-DEdftlfGA----SPEsalKYDA-SSRQVEIYPIAGTRPRGRR 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 272 PA----AD---RQQAEkLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLpasRTPC 344
Cdd:PRK13564 336 ADgsidRDldsRIELE-LRTDHKELAEHLMLVDLARNDLARICQPGSRYVADLLKVDRYSHVMHLVSRVVGEL---RHDL 411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 345 DLL---RAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSAGGGIVADSQ 421
Cdd:PRK13564 412 DALhayRACMNMGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTCIVIRSAFVENGIATVQAGAGVVLDSD 491
|
410
....*....|.
gi 1747561502 422 VEAEYQETFDK 432
Cdd:PRK13564 492 PQSEADETRNK 502
|
|
| PRK07093 |
PRK07093 |
para-aminobenzoate synthase component I; Validated |
177-433 |
1.35e-44 |
|
para-aminobenzoate synthase component I; Validated
Pssm-ID: 235932 [Multi-domain] Cd Length: 323 Bit Score: 158.11 E-value: 1.35e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 177 MTPQTYAEKFARVQAYLQSGDCYQVNLAQR------------FQATyqgdewqaftrlnasnRAPFSAFIRlDQgaILSL 244
Cdd:PRK07093 71 ISFEEYQQGFELVQEEIQAGNSYLLNLTYPtpietnlsleeiFQAS----------------KAKYKLLFK-DQ--FVCF 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 245 SPERFIHLAEGKIQTRPIKGTLPrlsdpaADRQQA-EKLAASPKDRAENLMIVDLMRNDIGRVAvpGSVRVPELFVVEPF 323
Cdd:PRK07093 132 SPEPFVRIEDNKISTYPMKGTID------ASLPNAeEKLLNDEKEFAEHATIVDLLRNDLSMVA--KNVRVTRFRYIDKI 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 324 PAVH----HLVSTITAQLPAS--RTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSvcG-TLDTSI 396
Cdd:PRK07093 204 KTNKgeilQTSSEISGTLPENwqENIGDILAKLLPAGSITGAPKEKTVEIIEQAEGYERGFYTGVFGYFD--GeSLDSAV 281
|
250 260 270
....*....|....*....|....*....|....*..
gi 1747561502 397 TIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDKV 433
Cdd:PRK07093 282 MIRFIEQENDGLYFKSGGGITIDSDLKDEYNELIQKV 318
|
|
| PRK06404 |
PRK06404 |
anthranilate synthase component I; Reviewed |
169-437 |
2.77e-43 |
|
anthranilate synthase component I; Reviewed
Pssm-ID: 102361 [Multi-domain] Cd Length: 351 Bit Score: 155.41 E-value: 2.77e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 169 LTSAWRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYqgDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPER 248
Cdd:PRK06404 94 KTVKLKGNYNDISLSLKIKELIELIRAGEVLQVVISREFEANI--DFKEKLSEFINNDRSRYVFYYRFGKYRVVGSSPEN 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 249 FIHLAEGKIQTRPIKGTLPrlsdpaaDRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHH 328
Cdd:PRK06404 172 VFTVNGNIINVDPIAGTYD-------DKILSNELLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVMKIEEFSSVKH 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 329 LVSTITAQLpaSRTP-CDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSvCGTLDTSITIRTLTACDGQ 407
Cdd:PRK06404 245 LVSQVTAKF--SNASyRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGIIS-KGYTDMALVIRTAYSHGNG 321
|
250 260 270
....*....|....*....|....*....|
gi 1747561502 408 LYCSAGGGIVADSQVEAEYQETFDKVNRIL 437
Cdd:PRK06404 322 FRVRAGAGIVKDSDPEDEVNEIYSKARSVM 351
|
|
| PRK13566 |
PRK13566 |
anthranilate synthase component I; |
94-441 |
2.05e-38 |
|
anthranilate synthase component I;
Pssm-ID: 237429 [Multi-domain] Cd Length: 720 Bit Score: 147.76 E-value: 2.05e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 94 GALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVVSLLSHSdvearLAW-------LNAQQPAAAPD 166
Cdd:PRK13566 156 GLYGAFGYDLAFQFEPIEQKLPRPDDQRDLVLYLPDEILVVDHYAARAWVDRYE-----FAVggvstegLPRETAPSPYK 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 167 FRLTSAWRSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGAIL-SLS 245
Cdd:PRK13566 231 PTTARPGFADHAPGEYAALVEKAKESFRRGDLFEVVPGQTFYEPCERSPSEIFRRLKEINPSPYGFFINLGDGEYLvGAS 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 246 PERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPA 325
Cdd:PRK13566 311 PEMFVRVEGRRVETCPISGTIKRGADAIGDAEQIRKLLNSKKDESELTMCTDVDRNDKSRVCEPGSVKVIGRRQIEMYSR 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 326 VHHLVSTITAQLpasRTPCDLLRA------AFpggSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIR 399
Cdd:PRK13566 391 LIHTVDHVEGRL---RPGFDALDAflthawAV---TVTGAPKLWAMQFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLR 464
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1747561502 400 TLTACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQLE 441
Cdd:PRK13566 465 TIRIKDGVAEVRVGATLLFDSDPEAEEAETELKASALLQALR 506
|
|
| MenF |
COG1169 |
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ... |
174-429 |
3.89e-34 |
|
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440783 [Multi-domain] Cd Length: 353 Bit Score: 130.66 E-value: 3.89e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 174 RSNMTPQTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQG--DEWQAFTRLNASN---------RAPFSAFIrldqGAil 242
Cdd:COG1169 83 RGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEpiDPRALLARLRRRNpdcytfaveLGAGDGFV----GA-- 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 243 slSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVpgSVRVPElfvvEP 322
Cdd:COG1169 157 --SPERLVRRRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREALAPLCS--SLDVPE----EP 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 323 F----PAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITI 398
Cdd:COG1169 229 EllrlRNVQHLATPITGTLDPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAVAI 308
|
250 260 270
....*....|....*....|....*....|.
gi 1747561502 399 RTLTACDGQLYCSAGGGIVADSQVEAEYQET 429
Cdd:COG1169 309 RSALIDGNRARLFAGAGIVAGSDPEAEWAET 339
|
|
| PRK07912 |
PRK07912 |
salicylate synthase; |
198-436 |
9.02e-27 |
|
salicylate synthase;
Pssm-ID: 169151 [Multi-domain] Cd Length: 449 Bit Score: 111.81 E-value: 9.02e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 198 CYQVNLAQRFQATYqgdewqaftRLNASNRAPFSAFI-RLDQGAILSLSPERFIHL-AEGKIQTRPIKGTLPRLSDPAAD 275
Cdd:PRK07912 210 CVEVPFAVDFPATY---------RLGRRHNTPVRSFLlRLGGIRALGYSPELVTAVrADGVVITEPLAGTRAFGRGAAID 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 276 RQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLPASRTPCDLLRAAFPGGS 355
Cdd:PRK07912 281 RLARDDLESNSKEIVEHAISVRSSLAEITEIAEPGSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVT 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 356 ITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDKVNR 435
Cdd:PRK07912 361 ASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLST 440
|
.
gi 1747561502 436 I 436
Cdd:PRK07912 441 L 441
|
|
| Anth_synt_I_N |
pfam04715 |
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) ... |
22-141 |
2.90e-23 |
|
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) catalyzes the first step in the biosynthesis of tryptophan. Component I catalyzes the formation of anthranilate using ammonia and chorismate. The catalytic site lies in the adjacent region, described in the chorismate binding enzyme family (pfam00425). This region is involved in feedback inhibition by tryptophan. This family also contains a region of Para-aminobenzoate synthase component I (EC 4.1.3.-).
Pssm-ID: 428082 [Multi-domain] Cd Length: 140 Bit Score: 95.07 E-value: 2.90e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 22 FARLSHLPWAMLLHSghADHPYSRFDIVVADPVRTVTSEN------------QPSTHDPLIQLQEAIDELGLSATPNPDI 89
Cdd:pfam04715 9 YLKLAGEPHSFLLES--AEGGEGRYSFIGINPLLTIKSKNgevsvsgpdgqeLEQEDGPLDALRALLARFRIEDSPPTLP 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1747561502 90 PFQGGALGVFGYDLGRRFETLPSVAKADIPLPDMAVGLYDWALIVDHHKQVV 141
Cdd:pfam04715 87 PFSGGLVGYLGYDLVRYIEKLPRTAPDDLNLPDARLILYEDLIVFDHQENKL 138
|
|
| PRK07054 |
PRK07054 |
isochorismate synthase; |
97-429 |
6.73e-23 |
|
isochorismate synthase;
Pssm-ID: 235920 [Multi-domain] Cd Length: 475 Bit Score: 100.61 E-value: 6.73e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 97 GVFGYD-LGRRFETLPSVAKADIPLPDMAV---GLYDWAL---IVDHHKQVVSLLSHSDVEA-RLAWLNAQQPAAAPDFR 168
Cdd:PRK07054 108 GGFRFDpRGPRSAHWQAFADASLTLAKLLVvreGEAYWAVcqhLVAAHDDPAALAGACCARIeRLARPAPAADDDAPRLL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 169 LTSAWRSNMtpqtYAEKFARVQAYLQSGDCYQVNLA--QRFQATYQGDEWQAFTRLNASN-RAPFSAFIRlDQGAILSLS 245
Cdd:PRK07054 188 RASALQARE----WQHEVRRAVDAIRGGAFGKVVLArdVLQQYARPVAIGPLLRRLRLRDpHAHLFAFRR-GNACFLGAT 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 246 PERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNdiGRVAVPGSVRVPELFVVEPFPA 325
Cdd:PRK07054 263 PERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALMASAKDRLEHALVVDAIRA--ALAPLSRALDIPDQPSLHRLPR 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 326 VHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACD 405
Cdd:PRK07054 341 LQHLSTPIRATLAPDATLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFAVALRSALITG 420
|
330 340
....*....|....*....|....
gi 1747561502 406 GQLYCSAGGGIVADSQVEAEYQET 429
Cdd:PRK07054 421 GACRLFAGCGIVADSEPASEYRET 444
|
|
| PRK06923 |
PRK06923 |
isochorismate synthase DhbC; Validated |
179-440 |
2.60e-19 |
|
isochorismate synthase DhbC; Validated
Pssm-ID: 235886 [Multi-domain] Cd Length: 399 Bit Score: 89.41 E-value: 2.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 179 PQTYAEKFARVQAYLQSGDCYQVNLAQRFQ--ATYQGDEWQAFTRLNASNRAPFSAFIRLDQG------AILSLSPERFI 250
Cdd:PRK06923 121 PEVYMNGVKQGIAKIQDGDLKKIVLSRSLDvkSSEKIDKQKLLRELAEHNKHGYTFAVNLPKDenenskTLIGASPELLV 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 251 HLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDlmrndigrvAVPGSVR-------VPELFVVEPF 323
Cdd:PRK06923 201 SRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVE---------AVAAALRpychtlhVPEKPSVIHT 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 324 PAVHHLVSTITAQLP-ASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLT 402
Cdd:PRK06923 272 EAMWHLSTEVKGELKdPNTSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAE 351
|
250 260 270
....*....|....*....|....*....|....*...
gi 1747561502 403 ACDGQLYCSAGGGIVADSQVEAEYQETFDKVNRILQQL 440
Cdd:PRK06923 352 VEENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKAM 389
|
|
| PRK06772 |
PRK06772 |
salicylate synthase; |
180-436 |
3.59e-18 |
|
salicylate synthase;
Pssm-ID: 102546 [Multi-domain] Cd Length: 434 Bit Score: 86.33 E-value: 3.59e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 180 QTYAEKFARVQAYLQSGDCYQVNLAQRFQATYQGDEWQAFTRLNASNRAPFSAFIRLDQGAILSLSPERFIHLAEGKIQT 259
Cdd:PRK06772 173 EAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSFMFRQEGREALGFSPELVMSVTGNKVVT 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 260 RPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITAQLPA 339
Cdd:PRK06772 253 EPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAE 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 340 SRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCgTLDTSITIRTLTACDGQLYCSAGGGIVAD 419
Cdd:PRK06772 333 NKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDT-RFDAALVLRSVFQDSQRCWIQAGAGIIAQ 411
|
250
....*....|....*..
gi 1747561502 420 SQVEAEYQETFDKVNRI 436
Cdd:PRK06772 412 STPERELTETREKLASI 428
|
|
| PRK15016 |
PRK15016 |
isochorismate synthase EntC; Provisional |
174-437 |
7.52e-18 |
|
isochorismate synthase EntC; Provisional
Pssm-ID: 184977 [Multi-domain] Cd Length: 391 Bit Score: 84.92 E-value: 7.52e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 174 RSNMTPQ-TYAEKFARVQAYLQSGDCYQVNLAQRFQATYQG--DEWQAFTRLNASNRAPFSAFIRL-DQGAILSLSPERF 249
Cdd:PRK15016 120 RQAIPEQtTFEAMVARAAALTATPQVDKVVLSRLIDITTDAaiDSGALLERLIAQNPVSYNFHVPLaDGGVLLGASPELL 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 250 IHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIG----RVAVPGSvrvPELFVVepfPA 325
Cdd:PRK15016 200 LRKDGERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRerssELHVPSS---PQLITT---PT 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 326 VHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTLDTSITIRTLTACD 405
Cdd:PRK15016 274 LWHLATPFEGKANAQENALTLACLLHPTPALSGFPHQAAKQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRE 353
|
250 260 270
....*....|....*....|....*....|..
gi 1747561502 406 GQLYCSAGGGIVADSQVEAEYQETFDKVNRIL 437
Cdd:PRK15016 354 NQVRLFAGAGIVPASSPLGEWRETGVKLSTML 385
|
|
| PRK15012 |
PRK15012 |
menaquinone-specific isochorismate synthase; Provisional |
238-432 |
3.71e-09 |
|
menaquinone-specific isochorismate synthase; Provisional
Pssm-ID: 184974 [Multi-domain] Cd Length: 431 Bit Score: 58.32 E-value: 3.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 238 QGAILSLSPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVPGSVRVPEl 317
Cdd:PRK15012 231 ENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQ- 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 318 fvVEPFPAVHHLVSTI-TAQLPASRTPCdlLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTlDTSI 396
Cdd:PRK15012 310 --VLRLRKVQHLRRCIwTSLNKADDVIC--LHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQS-EFCV 384
|
170 180 190
....*....|....*....|....*....|....*.
gi 1747561502 397 TIRTLTACDGQLYCSAGGGIVADSQVEAEYQETFDK 432
Cdd:PRK15012 385 SLRSAKVSGNVVRLYAGAGIVRGSDPEQEWQEIDNK 420
|
|
| PLN02786 |
PLN02786 |
isochorismate synthase |
245-441 |
4.86e-09 |
|
isochorismate synthase
Pssm-ID: 178383 [Multi-domain] Cd Length: 533 Bit Score: 58.26 E-value: 4.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 245 SPERFIHLAEGKIQTRPIKGTLPRLSDPAADRQQAEKLAASPKDRAENLMIVDLMRNDIGRVAVpgsvRVpelfVVEP-- 322
Cdd:PLN02786 330 TPEQLFHRKGLGVCSEALAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICD----RV----VVEPhk 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1747561502 323 ----FPAVHHLVSTITAQLPASRTPCDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCGSIGYVSVCGTlDTSITI 398
Cdd:PLN02786 402 airkLARVQHLYAQLAGRLRSEDDEFDILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFGGGES-EFAVGI 480
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1747561502 399 RTLTACDGQ---LYcsAGGGIVADSQVEAEYQETFDKVNRILQQLE 441
Cdd:PLN02786 481 RSALVEKGLgalIY--AGTGIVEGSNPSSEWNELELKISQFTKSLE 524
|
|
| |
