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Conserved domains on  [gi|1750814991|gb|KAA8700290|]
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helix-turn-helix transcriptional regulator [Lactococcus lactis subsp. hordniae]

Protein Classification

XRE family transcriptional regulator( domain architecture ID 11443577)

XRE (Xenobiotic Response Element) family transcriptional regulator is a helix-turn-helix domain-containing transcriptional regulator with a peptidase S24 LexA-like domain

Gene Ontology:  GO:0003677
PubMed:  10473770|15808743|10556324

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG2932 COG2932
Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains [Mobilome: ...
 123-241 6.53e-17

Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains [Mobilome: prophages, transposons];


:

Pssm-ID: 442176  Cd Length: 121  Bit Score: 74.23  E-value: 6.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 123 LSAGYGEGYTQEY-GKEIVYWNQQIKHDRAIIIRGNSMEPDYHYGQIALISYQNYIDVPGGIYAVDDieRGLAYIKSVYM 201
Cdd:COG2932     8 ASAGGGAFNEVEEpVDKLEFPGLPPDNLFAVRVSGDSMEPTIRDGDIVLVDPSDTEIRDGGIYVVRT--DGELLVKRLQR 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1750814991 202 E-DEHIRLVSLNDEedfegnrlFPDILLPRNE--NIRIIGKVV 241
Cdd:COG2932    86 RpDGKLRLISDNPA--------YPPIEIPPEDadEIEIIGRVV 120
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-66 3.22e-15

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 68.87  E-value: 3.22e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1750814991   1 MEFHEILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYLLGET 66
Cdd:COG1396     6 KALGERLRELRKARGLTQEELAERLGV-SRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGA 70
 
Name Accession Description Interval E-value
COG2932 COG2932
Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains [Mobilome: ...
 123-241 6.53e-17

Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains [Mobilome: prophages, transposons];


Pssm-ID: 442176  Cd Length: 121  Bit Score: 74.23  E-value: 6.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 123 LSAGYGEGYTQEY-GKEIVYWNQQIKHDRAIIIRGNSMEPDYHYGQIALISYQNYIDVPGGIYAVDDieRGLAYIKSVYM 201
Cdd:COG2932     8 ASAGGGAFNEVEEpVDKLEFPGLPPDNLFAVRVSGDSMEPTIRDGDIVLVDPSDTEIRDGGIYVVRT--DGELLVKRLQR 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1750814991 202 E-DEHIRLVSLNDEedfegnrlFPDILLPRNE--NIRIIGKVV 241
Cdd:COG2932    86 RpDGKLRLISDNPA--------YPPIEIPPEDadEIEIIGRVV 120
Peptidase_S24 pfam00717
Peptidase S24-like;
124-241 1.06e-15

Peptidase S24-like;


Pssm-ID: 425835  Cd Length: 116  Bit Score: 71.08  E-value: 1.06e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 124 SAGYGEgYTQEYGKEIVYWNQQI----KHDRAIIIRGNSMEPDYHYGQIALISYQNYIDvPGGIYAVDdIErGLAYIKSV 199
Cdd:pfam00717   7 AAGAPI-LAEEEIEGYLPLPESLlsppGNLFALRVKGDSMEPGIPDGDLVLVDPSREAR-NGDIVVAR-LD-GEATVKRL 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1750814991 200 YMEDEHIRLVSLNDEedfegnrlFPDILLPRNENIRIIGKVV 241
Cdd:pfam00717  83 YRDGGGIRLISLNPE--------YPPIELPAEDDVEIIGRVV 116
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-66 3.22e-15

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 68.87  E-value: 3.22e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1750814991   1 MEFHEILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYLLGET 66
Cdd:COG1396     6 KALGERLRELRKARGLTQEELAERLGV-SRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGA 70
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 5-62 4.97e-12

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 59.49  E-value: 4.97e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1750814991   5 EILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYL 62
Cdd:cd00093     2 ERLKELRKEKGLTQEELAEKLGV-SRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-62 9.80e-11

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 55.99  E-value: 9.80e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1750814991    7 LKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYL 62
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGV-SRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 7-62 1.07e-09

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 52.93  E-value: 1.07e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1750814991   7 LKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYL 62
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGV-SRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
Peptidase_S24_S26 cd06462
The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal ...
 150-240 1.55e-09

The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The S26 type I signal peptidase (SPase) family also includes mitochondrial inner membrane protease (IMP)-like members. SPases are essential membrane-bound proteases which function to cleave away the amino-terminal signal peptide from the translocated pre-protein, thus playing a crucial role in the transport of proteins across membranes in all living organisms. All members in this superfamily are unique serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases.


Pssm-ID: 119396 [Multi-domain]  Cd Length: 84  Bit Score: 53.42  E-value: 1.55e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 150 RAIIIRGNSMEPDYHYGQIALISYQNYIDVPGGIYAVdDIERGLAYIKSVYMEDE--HIRLVSLNDEedfegnrlFPDIL 227
Cdd:cd06462     1 FALRVEGDSMEPTIPDGDLVLVDKSSYEPKRGDIVVF-RLPGGELTVKRVIGLPGegHYFLLGDNPN--------SPDSR 71

                          90
                  ....*....|...
gi 1750814991 228 LPRNENIRIIGKV 240
Cdd:cd06462    72 IDGPPELDIVGVV 84
 
Name Accession Description Interval E-value
COG2932 COG2932
Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains [Mobilome: ...
 123-241 6.53e-17

Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains [Mobilome: prophages, transposons];


Pssm-ID: 442176  Cd Length: 121  Bit Score: 74.23  E-value: 6.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 123 LSAGYGEGYTQEY-GKEIVYWNQQIKHDRAIIIRGNSMEPDYHYGQIALISYQNYIDVPGGIYAVDDieRGLAYIKSVYM 201
Cdd:COG2932     8 ASAGGGAFNEVEEpVDKLEFPGLPPDNLFAVRVSGDSMEPTIRDGDIVLVDPSDTEIRDGGIYVVRT--DGELLVKRLQR 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1750814991 202 E-DEHIRLVSLNDEedfegnrlFPDILLPRNE--NIRIIGKVV 241
Cdd:COG2932    86 RpDGKLRLISDNPA--------YPPIEIPPEDadEIEIIGRVV 120
Peptidase_S24 pfam00717
Peptidase S24-like;
124-241 1.06e-15

Peptidase S24-like;


Pssm-ID: 425835  Cd Length: 116  Bit Score: 71.08  E-value: 1.06e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 124 SAGYGEgYTQEYGKEIVYWNQQI----KHDRAIIIRGNSMEPDYHYGQIALISYQNYIDvPGGIYAVDdIErGLAYIKSV 199
Cdd:pfam00717   7 AAGAPI-LAEEEIEGYLPLPESLlsppGNLFALRVKGDSMEPGIPDGDLVLVDPSREAR-NGDIVVAR-LD-GEATVKRL 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1750814991 200 YMEDEHIRLVSLNDEedfegnrlFPDILLPRNENIRIIGKVV 241
Cdd:pfam00717  83 YRDGGGIRLISLNPE--------YPPIELPAEDDVEIIGRVV 116
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-66 3.22e-15

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 68.87  E-value: 3.22e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1750814991   1 MEFHEILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYLLGET 66
Cdd:COG1396     6 KALGERLRELRKARGLTQEELAERLGV-SRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGA 70
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-67 2.88e-12

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 60.25  E-value: 2.88e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1750814991   1 MEFHEILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYLLGETN 67
Cdd:COG1476     3 KKLGNRLKELRKERGLTQEELAELLGV-SRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 5-62 4.97e-12

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 59.49  E-value: 4.97e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1750814991   5 EILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYL 62
Cdd:cd00093     2 ERLKELRKEKGLTQEELAEKLGV-SRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-62 9.80e-11

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 55.99  E-value: 9.80e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1750814991    7 LKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYL 62
Cdd:smart00530   2 LKELREEKGLTQEELAEKLGV-SRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 2-61 7.14e-10

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 53.79  E-value: 7.14e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991   2 EFHEILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSY 61
Cdd:COG1813    12 DYGERIREAREARGLSQEELAEKLGV-SESTIRRIERGEATPSLDTLRKLEKALGISLAE 70
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 7-62 1.07e-09

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 52.93  E-value: 1.07e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1750814991   7 LKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYL 62
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGV-SRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
Peptidase_S24_S26 cd06462
The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal ...
 150-240 1.55e-09

The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The S26 type I signal peptidase (SPase) family also includes mitochondrial inner membrane protease (IMP)-like members. SPases are essential membrane-bound proteases which function to cleave away the amino-terminal signal peptide from the translocated pre-protein, thus playing a crucial role in the transport of proteins across membranes in all living organisms. All members in this superfamily are unique serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases.


Pssm-ID: 119396 [Multi-domain]  Cd Length: 84  Bit Score: 53.42  E-value: 1.55e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 150 RAIIIRGNSMEPDYHYGQIALISYQNYIDVPGGIYAVdDIERGLAYIKSVYMEDE--HIRLVSLNDEedfegnrlFPDIL 227
Cdd:cd06462     1 FALRVEGDSMEPTIPDGDLVLVDKSSYEPKRGDIVVF-RLPGGELTVKRVIGLPGegHYFLLGDNPN--------SPDSR 71

                          90
                  ....*....|...
gi 1750814991 228 LPRNENIRIIGKV 240
Cdd:cd06462    72 IDGPPELDIVGVV 84
S24_LexA-like cd06529
Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of ...
 150-241 1.84e-09

Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The LexA-like proteins contain two-domains: an N-terminal DNA binding domain and a C-terminal domain (CTD) that provides LexA dimerization as well as cleavage activity. They undergo autolysis, cleaving at an Ala-Gly or a Cys-Gly bond, separating the DNA-binding domain from the rest of the protein. In the presence of single-stranded DNA, the LexA, UmuD and MucA proteins interact with RecA, activating self cleavage, thus either derepressing transcription in the case of LexA or activating the lesion-bypass polymerase in the case of UmuD and MucA. The LexA proteins are serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases. LexA sequence homologs are found in almost all of the bacterial genomes sequenced to date, covering a large number of phyla, suggesting both, an ancient origin and a widespread distribution of lexA and the SOS response.


Pssm-ID: 119397 [Multi-domain]  Cd Length: 81  Bit Score: 52.95  E-value: 1.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 150 RAIIIRGNSMEPDYHYGQIALISYQNYIdVPGGIYAVDDieRGLAYIKSVYME-DEHIRLVSLNDEedfegnrlFPDILL 228
Cdd:cd06529     1 FALRVKGDSMEPTIPDGDLVLVDPSDTP-RDGDIVVARL--DGELTVKRLQRRgGGRLRLISDNPA--------YPPIEI 69

                          90
                  ....*....|...
gi 1750814991 229 PRnENIRIIGKVV 241
Cdd:cd06529    70 DE-EELEIVGVVG 81
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 1-63 4.31e-05

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 41.16  E-value: 4.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1750814991   1 MEFHEILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYLL 63
Cdd:COG3620    16 DTLGEALRLMRKELGLSQLPVAELVGV-SQSDILRIESGKRDPTVSTLEKIAEALGKELSAVL 77
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 5-63 6.72e-05

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 39.96  E-value: 6.72e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1750814991   5 EILKELRKNSGITQVQMAQKLNLaSQGAYRKYETGEGFPHLERLLLISKIFNVSVSYLL 63
Cdd:pfam12844   2 ERLRKAREERGLTQEELAERLGI-SRSQLSAIENGKSVPPAETLYKIAELLGVPANWLL 59
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 7-58 1.40e-04

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 39.05  E-value: 1.40e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1750814991   7 LKELRKNSGITQVQMAQKLNLaSQGAYRKYETGE-GFPHLERLLLISKIFNVS 58
Cdd:pfam13560   6 LRRLRERAGLSQEALARRLGV-SRSTLSRLETGRrGRPSPAVVERLARALGVD 57
LexA COG1974
SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, ...
 151-241 8.38e-04

SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, Signal transduction mechanisms];


Pssm-ID: 441577 [Multi-domain]  Cd Length: 199  Bit Score: 39.51  E-value: 8.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750814991 151 AIIIRGNSM-EPDYHYGQIALISYQNYIDvPGGIYAVDdIErGLAYIKSVYMEDEHIRLVSLNDEedfegnrlFPDILLP 229
Cdd:COG1974   114 ALRVKGDSMiDAGILDGDLVIVDRQLEAE-NGDIVVAL-ID-GEATVKRLYKEGGRVRLQPENPA--------YPPIIIE 182

                          90
                  ....*....|..
gi 1750814991 230 RnENIRIIGKVV 241
Cdd:COG1974   183 G-DDVEILGVVV 193
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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