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Conserved domains on  [gi|1750864350|gb|KAA8748771|]
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DeoR/GlpR transcriptional regulator [Priestia megaterium]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-250 1.50e-88

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


:

Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 262.76  E-value: 1.50e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   1 MLKTKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGG-VAVNHVKLE-SFNERQTRNQFQKR 78
Cdd:COG1349     1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGaVLVSSAAAEpPFAERETLNAEEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  79 LIAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKD-KSITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANP 157
Cdd:COG1349    81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDrRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 158 VKNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK-VDVSYQ 236
Cdd:COG1349   161 LRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAgPPPELL 240

                         250
                  ....*....|....
gi 1750864350 237 HYAKENEITLILAE 250
Cdd:COG1349   241 EALEEAGVEVIVAE 254
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-250 1.50e-88

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 262.76  E-value: 1.50e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   1 MLKTKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGG-VAVNHVKLE-SFNERQTRNQFQKR 78
Cdd:COG1349     1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGaVLVSSAAAEpPFAERETLNAEEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  79 LIAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKD-KSITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANP 157
Cdd:COG1349    81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDrRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 158 VKNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK-VDVSYQ 236
Cdd:COG1349   161 LRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAgPPPELL 240

                         250
                  ....*....|....
gi 1750864350 237 HYAKENEITLILAE 250
Cdd:COG1349   241 EALEEAGVEVIVAE 254
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 72-230 6.10e-54

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 171.16  E-value: 6.10e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  72 RNQFQKRLIAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKDKS-ITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFS 150
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRnLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 151 SFNHANPVKNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK 230
Cdd:pfam00455  81 GPLAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
srlR PRK10434
DNA-binding transcriptional repressor;
6-251 7.14e-38

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 133.27  E-value: 7.14e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   6 RIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAVNHVKLESFNERQTR-NQFQKRLIAKTA 84
Cdd:PRK10434    6 RQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLiNTHKKELIAEAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  85 AQYVEDGDVIFIDSGTTTLEMIEFLKD-KSITIVTNSLDVIVKALPFDALKVI-STGGYLERETQSFSSFNHANPVKNYN 162
Cdd:PRK10434   86 VSLIHDGDSIILDAGSTVLQMVPLLSRfNNITVMTNSLHIVNALSELDNEQTIlMPGGTFRKKSASFHGQLAENAFEHFT 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 163 FDKVFMASTGISISNGVTNSSPVESeIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK-VDVSYQHYAKE 241
Cdd:PRK10434  166 FDKLFIGTDGIDLNAGVTTFNEVYT-VSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAgIDPAFRQALEE 244

                         250
                  ....*....|
gi 1750864350 242 NEITLILAEE 251
Cdd:PRK10434  245 KGIEVIITGE 254
AgaR NF040755
transcriptional repressor AgaR;
5-230 9.75e-38

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 132.78  E-value: 9.75e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   5 KRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAVNHVKLESF----NERQTRNQFQKRLI 80
Cdd:NF040755    6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPGAepsvEDKSRLNTAVKRLI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  81 AKTAAQYVEDGDVIFIDSGTTTLEMIEFLKDKSITIV-TNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANPVK 159
Cdd:NF040755   86 AAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVmTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQSLQ 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1750864350 160 NYNFDKVFMASTGISISNGVTNSSPVES-------EIKETVIkrstkvfLLADHTKFDKYAMITYCQLHEVDYLITDK 230
Cdd:NF040755  166 NYHFDKLFLGVDGFDLERGITTHNEDEArlnrrmcEVAERII-------AVTDSSKFGRSSLHKIRDTGRIDTLITDS 236
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-58 1.76e-13

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 63.01  E-value: 1.76e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1750864350    6 RIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAV 58
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-250 1.50e-88

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 262.76  E-value: 1.50e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   1 MLKTKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGG-VAVNHVKLE-SFNERQTRNQFQKR 78
Cdd:COG1349     1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGaVLVSSAAAEpPFAERETLNAEEKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  79 LIAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKD-KSITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANP 157
Cdd:COG1349    81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDrRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 158 VKNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK-VDVSYQ 236
Cdd:COG1349   161 LRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAgPPPELL 240

                         250
                  ....*....|....
gi 1750864350 237 HYAKENEITLILAE 250
Cdd:COG1349   241 EALEEAGVEVIVAE 254
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 72-230 6.10e-54

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 171.16  E-value: 6.10e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  72 RNQFQKRLIAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKDKS-ITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFS 150
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRnLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 151 SFNHANPVKNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK 230
Cdd:pfam00455  81 GPLAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
srlR PRK10434
DNA-binding transcriptional repressor;
6-251 7.14e-38

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 133.27  E-value: 7.14e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   6 RIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAVNHVKLESFNERQTR-NQFQKRLIAKTA 84
Cdd:PRK10434    6 RQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLiNTHKKELIAEAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  85 AQYVEDGDVIFIDSGTTTLEMIEFLKD-KSITIVTNSLDVIVKALPFDALKVI-STGGYLERETQSFSSFNHANPVKNYN 162
Cdd:PRK10434   86 VSLIHDGDSIILDAGSTVLQMVPLLSRfNNITVMTNSLHIVNALSELDNEQTIlMPGGTFRKKSASFHGQLAENAFEHFT 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 163 FDKVFMASTGISISNGVTNSSPVESeIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK-VDVSYQHYAKE 241
Cdd:PRK10434  166 FDKLFIGTDGIDLNAGVTTFNEVYT-VSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAgIDPAFRQALEE 244

                         250
                  ....*....|
gi 1750864350 242 NEITLILAEE 251
Cdd:PRK10434  245 KGIEVIITGE 254
AgaR NF040755
transcriptional repressor AgaR;
5-230 9.75e-38

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 132.78  E-value: 9.75e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   5 KRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAVNHVKLESF----NERQTRNQFQKRLI 80
Cdd:NF040755    6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPGAepsvEDKSRLNTAVKRLI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  81 AKTAAQYVEDGDVIFIDSGTTTLEMIEFLKDKSITIV-TNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANPVK 159
Cdd:NF040755   86 AAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVmTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQSLQ 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1750864350 160 NYNFDKVFMASTGISISNGVTNSSPVES-------EIKETVIkrstkvfLLADHTKFDKYAMITYCQLHEVDYLITDK 230
Cdd:NF040755  166 NYHFDKLFLGVDGFDLERGITTHNEDEArlnrrmcEVAERII-------AVTDSSKFGRSSLHKIRDTGRIDTLITDS 236
PRK09802 PRK09802
DeoR family transcriptional regulator;
4-251 9.30e-34

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 122.66  E-value: 9.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   4 TKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAV---NHVKLE-SFNERQTRNQFQKRL 79
Cdd:PRK09802   16 SERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALIcdsTTPSVEpSVEDKSALNTAMKRS 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  80 IAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKD-KSITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANPV 158
Cdd:PRK09802   96 VAKAAVELIQPGHRVILDSGTTTFEIARLMRKhTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 159 KNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK-VDVSYQH 237
Cdd:PRK09802  176 QNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEgIPADSLE 255

                         250
                  ....*....|....
gi 1750864350 238 YAKENEITLILAEE 251
Cdd:PRK09802  256 GLRKAGVEVILVGE 269
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
1-230 1.43e-24

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 98.01  E-value: 1.43e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   1 MLKTKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAVNHVKLE-SFNERQTRNQFQKRL 79
Cdd:PRK10906    1 MKQTQRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAALPSSSVNtPWHDRKATQTEEKER 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  80 IAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKD-KSITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANPV 158
Cdd:PRK10906   81 IARKVASQIPNGATLFIDIGTTPEAVAHALLNhSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDFI 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1750864350 159 KNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK 230
Cdd:PRK10906  161 SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDQ 232
PRK10411 PRK10411
L-fucose operon activator;
2-234 3.85e-24

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 96.80  E-value: 3.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   2 LKTKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAVNHVKLES----FNERQTRNQFQK 77
Cdd:PRK10411    1 MKAARQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDsgdpFHIRLKSHYAHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  78 RLIAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKDKSITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFSSFNHANP 157
Cdd:PRK10411   81 ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICQELGKRERIQLISSGGTLERKYGCYVNPSLISQ 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1750864350 158 VKNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDKVDVS 234
Cdd:PRK10411  161 LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVA 237
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 6-247 8.28e-23

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 93.22  E-value: 8.28e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   6 RIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQklvdeGHIKKV--YGGVAVNHVKLES---FNERQTRNQFQKRLI 80
Cdd:PRK10681    8 RIGQLLQALKRSDKLHLKDAAALLGVSEMTIRRDLN-----AHSAPVvlLGGYIVLEPRSAShylLSDQKSRLVEEKRRA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  81 AKTAAQYVEDGDVIFIDSGTTTLEMIEFLKDK-SITIVTNSLDVivkalpFDAL------KVISTGGYLERETQSFSSFN 153
Cdd:PRK10681   83 AQLAATLVEPNQTLFFDCGTTTPWIIEAIDNElPFTAVCYSLNT------FLALqekphcRAILCGGEFHASNAIFKPLD 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350 154 HANPVKNYNFDKVFMASTGISISNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDKV-D 232
Cdd:PRK10681  157 FQQTLDNICPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMAMAQKHVLVVDHSKFGKVRPARMGDLTRFDTVVSDRCpD 236

                         250
                  ....*....|....*
gi 1750864350 233 VSYQHYAKENEITLI 247
Cdd:PRK10681  237 DEFVKYAQAQRIKLM 251
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
1-230 8.07e-21

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 88.14  E-value: 8.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350   1 MLKTKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGG---VAVNHVKLESFNERQTRNQFQK 77
Cdd:PRK13509    1 MTEAQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGaeaITQQRPRWTPMNIHQAQNHDEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  78 RLIAKTAAQYVEDGDVIFIDSGTTTLEMIEFLKDKSITIVTNSLDVIVKALPFDALKVISTGGYLERETQSFSSFN-HAN 156
Cdd:PRK13509   81 VRIAKAASQLCNPGESVVINCGSTAFLLGRELCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQgSEN 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1750864350 157 PVknYNFDKVFMASTGISiSNGVTNSSPVESEIKETVIKRSTKVFLLADHTKFDKYAMITYCQLHEVDYLITDK 230
Cdd:PRK13509  161 SL--YAGHWMFTSGKGLT-ADGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGK 231
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-58 1.76e-13

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 63.01  E-value: 1.76e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1750864350    6 RIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAV 58
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
6-60 3.07e-13

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 62.66  E-value: 3.07e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1750864350   6 RIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGGVAVNH 60
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNS 55
COG3177 COG3177
Fic family protein [Transcription];
4-55 1.34e-06

Fic family protein [Transcription];


Pssm-ID: 442410 [Multi-domain]  Cd Length: 316  Bit Score: 48.53  E-value: 1.34e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1750864350   4 TKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEGHIKKVYGG 55
Cdd:COG3177   260 NERQRKLLELLFENPVLTASELAELLGVSRRTARRDLKDLVELGILEKVGGG 311
PRK00702 PRK00702
ribose-5-phosphate isomerase RpiA;
76-120 1.58e-04

ribose-5-phosphate isomerase RpiA;


Pssm-ID: 234816  Cd Length: 220  Bit Score: 41.59  E-value: 1.58e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1750864350  76 QKRLIAKTAAQYVEDGDVIFIDSGTTTLEMIEFL-----KDKSITIVTNS 120
Cdd:PRK00702    6 LKKAAAEAAAEYVEDGMIVGLGTGSTAAYFIDALgervkEGLIIGGVPTS 55
YobV COG2378
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ...
 1-47 3.18e-03

Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];


Pssm-ID: 441945 [Multi-domain]  Cd Length: 314  Bit Score: 38.14  E-value: 3.18e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1750864350   1 MLKTKRIQQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEG 47
Cdd:COG2378     1 MSRLERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRELG 47
DeoR COG2390
DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];
31-117 5.82e-03

DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];


Pssm-ID: 441955 [Multi-domain]  Cd Length: 301  Bit Score: 37.42  E-value: 5.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1750864350  31 VSKNTIRRDVQKLVDEGHIKkvyggVAVNHVKLESFN-ERQTRNQF-----------------QKRLIAKTAAQY----V 88
Cdd:COG2390    22 ISRRTVSRLLAEAREEGLVR-----ISITDPLAGLLElERELRERFglkevivvpgdsdddeeVLRALGRAAAEYlerlL 96

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1750864350  89 EDGDVIFIDSGTTTLEMIEFLKDKS---ITIV 117
Cdd:COG2390    97 KDGDVIGVGWGRTLAAVAEALPPLPlpdVTVV 128
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
8-47 7.13e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 36.82  E-value: 7.13e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1750864350   8 QQIQEYVFEHESVSLDDLVSVFEVSKNTIRRDVQKLVDEG 47
Cdd:COG2345    16 RRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEG 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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