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Conserved domains on  [gi|1754875174|gb|KAB0563266|]
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ATP-dependent helicase HrpB, partial [Helicobacter pullorum NCTC 12824]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DEAH_box_HrpB super family cl37013
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ...
 1-156 6.01e-68

ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]


The actual alignment was detected with superfamily member TIGR01970:

Pssm-ID: 273901 [Multi-domain]  Cd Length: 819  Bit Score: 220.02  E-value: 6.01e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWgRPYQA 80
Cdd:TIGR01970 113 GVGALIFDEFHERSLDADLGLALALDVQSSLRED--LKILAMSATLDGERLSSLLPDAPVVESEGRSFPVEIRY-LPLRG 189

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1754875174  81 GEFIEPRVVQTILEAVHDETGSILVFLPGQAEIRRVNQQLADALGdrPDVLLCPLHGELDLNAQRAAIDPAPAGKR 156
Cdd:TIGR01970 190 DQRLEDAVSRAVEHALASETGSILVFLPGQAEIRRVQEQLAERLD--SDVLICPLYGELSLAAQDRAIKPDPQGRR 263
 
Name Accession Description Interval E-value
DEAH_box_HrpB TIGR01970
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ...
 1-156 6.01e-68

ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 273901 [Multi-domain]  Cd Length: 819  Bit Score: 220.02  E-value: 6.01e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWgRPYQA 80
Cdd:TIGR01970 113 GVGALIFDEFHERSLDADLGLALALDVQSSLRED--LKILAMSATLDGERLSSLLPDAPVVESEGRSFPVEIRY-LPLRG 189

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1754875174  81 GEFIEPRVVQTILEAVHDETGSILVFLPGQAEIRRVNQQLADALGdrPDVLLCPLHGELDLNAQRAAIDPAPAGKR 156
Cdd:TIGR01970 190 DQRLEDAVSRAVEHALASETGSILVFLPGQAEIRRVQEQLAERLD--SDVLICPLYGELSLAAQDRAIKPDPQGRR 263
HrpA COG1643
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
1-156 1.08e-62

HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441249 [Multi-domain]  Cd Length: 836  Bit Score: 205.70  E-value: 1.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWGRPYQA 80
Cdd:COG1643   123 GVDTVIFDEFHERSLNADLLLALLLDLQPALRPD--LKLLVMSATLDAERFARLLGDAPVIESSGRTYPVEVRYRPLPAD 200

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1754875174  81 GEFIEPRVVQTILEAVHDETGSILVFLPGQAEIRRVNQQLADALGdrPDVLLCPLHGELDLNAQRAAIDPAPAGKR 156
Cdd:COG1643   201 ERDLEDAVADAVREALAEEPGDILVFLPGEREIRRTAEALRGRLP--PDTEILPLYGRLSAAEQDRAFAPAPHGRR 274
PRK11664 PRK11664
ATP-dependent RNA helicase HrpB; Provisional
 1-156 7.01e-57

ATP-dependent RNA helicase HrpB; Provisional


Pssm-ID: 236950 [Multi-domain]  Cd Length: 812  Bit Score: 189.75  E-value: 7.01e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWgRPYQA 80
Cdd:PRK11664  116 GVGLVILDEFHERSLQADLALALLLDVQQGLRDD--LKLLIMSATLDNDRLQQLLPDAPVIVSEGRSFPVERRY-QPLPA 192

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1754875174  81 GEFIEPRVVQTILEAVHDETGSILVFLPGQAEIRRVNQQLADALGDrpDVLLCPLHGELDLNAQRAAIDPAPAGKR 156
Cdd:PRK11664  193 HQRFDEAVARATAELLRQESGSLLLFLPGVGEIQRVQEQLASRVAS--DVLLCPLYGALSLAEQQKAILPAPAGRR 266
DEXHc_HrpB cd17990
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ...
 1-63 7.73e-22

DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438711 [Multi-domain]  Cd Length: 174  Bit Score: 85.85  E-value: 7.73e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRS 63
Cdd:cd17990   114 GVGAVILDEFHERSLDADLALALLLEVQQLLRDD--LRLLAMSATLDGDGLAALLPEAPVVES 174
 
Name Accession Description Interval E-value
DEAH_box_HrpB TIGR01970
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ...
 1-156 6.01e-68

ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 273901 [Multi-domain]  Cd Length: 819  Bit Score: 220.02  E-value: 6.01e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWgRPYQA 80
Cdd:TIGR01970 113 GVGALIFDEFHERSLDADLGLALALDVQSSLRED--LKILAMSATLDGERLSSLLPDAPVVESEGRSFPVEIRY-LPLRG 189

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1754875174  81 GEFIEPRVVQTILEAVHDETGSILVFLPGQAEIRRVNQQLADALGdrPDVLLCPLHGELDLNAQRAAIDPAPAGKR 156
Cdd:TIGR01970 190 DQRLEDAVSRAVEHALASETGSILVFLPGQAEIRRVQEQLAERLD--SDVLICPLYGELSLAAQDRAIKPDPQGRR 263
HrpA COG1643
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
1-156 1.08e-62

HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441249 [Multi-domain]  Cd Length: 836  Bit Score: 205.70  E-value: 1.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWGRPYQA 80
Cdd:COG1643   123 GVDTVIFDEFHERSLNADLLLALLLDLQPALRPD--LKLLVMSATLDAERFARLLGDAPVIESSGRTYPVEVRYRPLPAD 200

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1754875174  81 GEFIEPRVVQTILEAVHDETGSILVFLPGQAEIRRVNQQLADALGdrPDVLLCPLHGELDLNAQRAAIDPAPAGKR 156
Cdd:COG1643   201 ERDLEDAVADAVREALAEEPGDILVFLPGEREIRRTAEALRGRLP--PDTEILPLYGRLSAAEQDRAFAPAPHGRR 274
PRK11664 PRK11664
ATP-dependent RNA helicase HrpB; Provisional
 1-156 7.01e-57

ATP-dependent RNA helicase HrpB; Provisional


Pssm-ID: 236950 [Multi-domain]  Cd Length: 812  Bit Score: 189.75  E-value: 7.01e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWgRPYQA 80
Cdd:PRK11664  116 GVGLVILDEFHERSLQADLALALLLDVQQGLRDD--LKLLIMSATLDNDRLQQLLPDAPVIVSEGRSFPVERRY-QPLPA 192

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1754875174  81 GEFIEPRVVQTILEAVHDETGSILVFLPGQAEIRRVNQQLADALGDrpDVLLCPLHGELDLNAQRAAIDPAPAGKR 156
Cdd:PRK11664  193 HQRFDEAVARATAELLRQESGSLLLFLPGVGEIQRVQEQLASRVAS--DVLLCPLYGALSLAEQQKAILPAPAGRR 266
DEXHc_HrpB cd17990
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ...
 1-63 7.73e-22

DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438711 [Multi-domain]  Cd Length: 174  Bit Score: 85.85  E-value: 7.73e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDEqpLKILLMSATLEGDRLSGLLNDAPILRS 63
Cdd:cd17990   114 GVGAVILDEFHERSLDADLALALLLEVQQLLRDD--LRLLAMSATLDGDGLAALLPEAPVVES 174
SF2_C_RHA cd18791
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ...
 68-156 5.33e-19

C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350178 [Multi-domain]  Cd Length: 171  Bit Score: 78.73  E-value: 5.33e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174  68 FPVQMRW-----GRPYQAGEFIEP----RVVQTILEAVHDET-GSILVFLPGQAEIRRVNQQLADAL--GDRPDVLLCPL 135
Cdd:cd18791     1 FPVEVYYledilELLGISSEKEDPdyvdAAVRLILQIHRTEEpGDILVFLPGQEEIERLCELLREELlsPDLGKLLVLPL 80

                          90       100
                  ....*....|....*....|.
gi 1754875174 136 HGELDLNAQRAAIDPAPAGKR 156
Cdd:cd18791    81 HSSLPPEEQQRVFEPPPPGVR 101
PRK11131 PRK11131
ATP-dependent RNA helicase HrpA; Provisional
 5-156 2.57e-17

ATP-dependent RNA helicase HrpA; Provisional


Pssm-ID: 182986 [Multi-domain]  Cd Length: 1294  Bit Score: 77.79  E-value: 2.57e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754875174    5 LIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPILRSEGRMFPVQMRWgRPYQAGEFI 84
Cdd:PRK11131   190 IIIDEAHERSLNIDFILGYL---KELLPRRPDLKVIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRY-RPIVEEADD 265

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1754875174   85 EPR-VVQTILEAV----HDETGSILVFLPGQAEIRrvnqQLADALGDR--PDVLLCPLHGELDLNAQRAAIDPApAGKR 156
Cdd:PRK11131   266 TERdQLQAIFDAVdelgREGPGDILIFMSGEREIR----DTADALNKLnlRHTEILPLYARLSNSEQNRVFQSH-SGRR 339
DEXHc_RHA-like cd17917
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ...
 1-62 1.42e-14

DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438707 [Multi-domain]  Cd Length: 159  Bit Score: 66.71  E-value: 1.42e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALsLngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPILR 62
Cdd:cd17917   100 GYSHVILDEAHERSLDTDFLLGL-L--KDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIH 158
DEXHc_DHX33 cd17978
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ...
 3-61 1.92e-09

DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438710 [Multi-domain]  Cd Length: 178  Bit Score: 53.51  E-value: 1.92e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1754875174   3 GLLIFDEFHERSLDADLALAL--SLNGRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPIL 61
Cdd:cd17978   116 SVIILDEAHERTVHTDVLFGLvkSAQRRRKEQKLSPLKVIIMSATLDADLFSEYFNGAPVL 176
DEXHc_DHX36 cd17981
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ...
 2-62 2.68e-08

DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350739 [Multi-domain]  Cd Length: 180  Bit Score: 50.61  E-value: 2.68e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1754875174   2 VGLLIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPILR 62
Cdd:cd17981   122 VSHLVLDEIHERNLQSDVLMGIV---KDLLPFRSDLKVILMSATLNAEKFSDYFNNCPMIH 179
DEXHc_DHX16 cd17974
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ...
 4-62 1.10e-07

DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350732 [Multi-domain]  Cd Length: 174  Bit Score: 48.65  E-value: 1.10e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1754875174   4 LLIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPILR 62
Cdd:cd17974   118 VMIIDEAHERTLHTDILFGLV---KDIARFRPDLKLLISSATMDAEKFSAFFDDAPIFR 173
DEXHc_DHX40 cd17984
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ...
 4-61 2.31e-07

DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350742 [Multi-domain]  Cd Length: 178  Bit Score: 47.93  E-value: 2.31e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1754875174   4 LLIFDEFHERSLDADLALALSlngRDLF-----RDEQPLKILLMSATLEGDRLSGLLNDAPIL 61
Cdd:cd17984   117 VIILDEAHERSLTTDILFGLL---KKLFqekspNRKEHLKVVVMSATLELAKLSAFFGNCPVF 176
DEXHc_DHX34 cd17979
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ...
 5-62 2.79e-07

DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350737 [Multi-domain]  Cd Length: 170  Bit Score: 47.44  E-value: 2.79e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1754875174   5 LIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPILR 62
Cdd:cd17979   115 LILDEVHERHLHGDFLLGVL---RCLLRLRPDLKLILMSATINIELFSGYFEGAPVVQ 169
DEXHc_DHX15 cd17973
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ...
 3-61 6.65e-07

DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 438709 [Multi-domain]  Cd Length: 187  Bit Score: 46.64  E-value: 6.65e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1754875174   3 GLLIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPIL 61
Cdd:cd17973   130 SVIILDEAHERTLATDILMGLL---KEVVRRRPDLKLIVMSATLDAGKFQKYFDNAPLL 185
DEXHc_DHX57 cd17985
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ...
 1-61 1.23e-06

DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350743 [Multi-domain]  Cd Length: 177  Bit Score: 45.99  E-value: 1.23e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1754875174   1 GVGLLIFDEFHERSLDADLALalsLNGRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPIL 61
Cdd:cd17985   118 GVTHVIVDEVHERTEESDFLL---LVLKDLMVQRPDLKVILMSATLNAELFSDYFNSCPVI 175
DEXHc_DHX29 cd17975
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ...
 5-62 1.09e-05

DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350733 [Multi-domain]  Cd Length: 183  Bit Score: 43.37  E-value: 1.09e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1754875174   5 LIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPILR 62
Cdd:cd17975   128 IIVDEVHERSVQSDFLLIIL---KEILHKRSDLHLILMSATVDCEKFSSYFTHCPILR 182
DEXHc_HrpA cd17989
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ...
 5-61 1.15e-05

DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350747 [Multi-domain]  Cd Length: 173  Bit Score: 43.21  E-value: 1.15e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1754875174   5 LIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPIL 61
Cdd:cd17989   118 IIIDEAHERSLNIDFLLGYL---KQLLPRRPDLKVIITSATIDAERFSRHFNNAPII 171
DEXHc_DHX30 cd17976
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ...
 1-62 1.59e-05

DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350734 [Multi-domain]  Cd Length: 178  Bit Score: 42.86  E-value: 1.59e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPILR 62
Cdd:cd17976   119 GVSHVIVDEVHERDVNTDFLLILL---KGVLQLNPELRVVLMSATGDNQRLSRYFGGCPVVR 177
DEXHc_DHX9 cd17972
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ...
 1-61 8.74e-05

DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350730 [Multi-domain]  Cd Length: 234  Bit Score: 40.97  E-value: 8.74e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1754875174   1 GVGLLIFDEFHERSLDADLALALSLNGRDLFRDeqpLKILLMSATLEGDRLSGLLNDAPIL 61
Cdd:cd17972   175 GISHVIVDEIHERDINTDFLLVVLRDVVQAYPD---LRVILMSATIDTSMFCEYFFNCPVI 232
DEXHc_DHX8 cd17971
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ...
 4-60 1.40e-04

DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350729 [Multi-domain]  Cd Length: 179  Bit Score: 40.16  E-value: 1.40e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1754875174   4 LLIFDEFHERSLDADLALALSlngRDLFRDEQPLKILLMSATLEGDRLSGLLNDAPI 60
Cdd:cd17971   122 VIMLDEAHERTIHTDVLFGLL---KKTVQKRPDLKLIVTSATLDAVKFSQYFYEAPI 175
PHA02653 PHA02653
RNA helicase NPH-II; Provisional
 3-50 3.79e-03

RNA helicase NPH-II; Provisional


Pssm-ID: 177443 [Multi-domain]  Cd Length: 675  Bit Score: 36.49  E-value: 3.79e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1754875174   3 GLLIFDEFHERSLDADLALALSLNGRDLFRDeqplkILLMSATLEGDR 50
Cdd:PHA02653  293 GTVIIDEVHEHDQIGDIIIAVARKHIDKIRS-----LFLMTATLEDDR 335
DEXHc_DHX37 cd17982
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ...
 5-46 5.67e-03

DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350740 [Multi-domain]  Cd Length: 191  Bit Score: 35.41  E-value: 5.67e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1754875174   5 LIFDEFHERSLDADLALALsLNG-----RDLFRDEQ---PLKILLMSATL 46
Cdd:cd17982   122 IIIDEAHERSVNTDILIGM-LSRivplrAKLYLQDQtvkPLKLVIMSATL 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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