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Conserved domains on  [gi|1754900487|gb|KAB0587808|]
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K+/H+ antiporter subunit F [Comamonas kerstersii]

Protein Classification

cation:proton antiporter subunit F( domain architecture ID 10012679)

cation:proton antiporter subunit F, part of an antiporter complex involved in monovalent cation transport; important in resistance to high concentrations of Na+, K+, Li+ and/or alkali

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06161 PRK06161
putative monovalent cation/H+ antiporter subunit F; Reviewed
 5-92 1.28e-32

putative monovalent cation/H+ antiporter subunit F; Reviewed


:

Pssm-ID: 180435  Cd Length: 89  Bit Score: 108.40  E-value: 1.28e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  5 LVWVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKF 84
Cdd:PRK06161   2 LAWAILIAQVALALAMLLALWRLLRGPRAQDRILALDTLYINAILLLLVFGIRLGSTIYFEAALLIALLGFVSTVALAKF 81


                 ....*...
gi 1754900487 85 LLRGEVIE 92
Cdd:PRK06161  82 LLRGEVIE 89
 
Name Accession Description Interval E-value
PRK06161 PRK06161
putative monovalent cation/H+ antiporter subunit F; Reviewed
 5-92 1.28e-32

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 180435  Cd Length: 89  Bit Score: 108.40  E-value: 1.28e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  5 LVWVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKF 84
Cdd:PRK06161   2 LAWAILIAQVALALAMLLALWRLLRGPRAQDRILALDTLYINAILLLLVFGIRLGSTIYFEAALLIALLGFVSTVALAKF 81


                 ....*...
gi 1754900487 85 LLRGEVIE 92
Cdd:PRK06161  82 LLRGEVIE 89
MnhF COG2212
Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];
4-87 9.06e-20

Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441814  Cd Length: 84  Bit Score: 75.53  E-value: 9.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  4 WLVWVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAK 83
Cdd:COG2212    1 MMTTVLLIALALLALALLLALYRLIRGPTLADRVLALDTLGTNAVALLALLGILTGRPLYLDVALVLALLGFVGTVAFAR 80


                 ....
gi 1754900487 84 FLLR 87
Cdd:COG2212   81 FLER 84
MrpF_PhaF pfam04066
Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF ...
 35-86 2.18e-09

Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF family are predicted to be an integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation. It is also involved in symbiosis in Rhizobium meliloti. MrpF is part of a Na+/H+ antiporter complex, also involved in pH homeostasis. MrpF is thought to be an efflux system for Na+ and cholate. The Mrp system in Bacilli may also have primary energization capacities.


Pssm-ID: 461156  Cd Length: 52  Bit Score: 48.55  E-value: 2.18e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1754900487 35 DRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKFLL 86
Cdd:pfam04066  1 DRVVALDTLGTNIVALLALLAILTGRPAYLDVALVLALLGFVGTVAFARFLE 52
 
Name Accession Description Interval E-value
PRK06161 PRK06161
putative monovalent cation/H+ antiporter subunit F; Reviewed
 5-92 1.28e-32

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 180435  Cd Length: 89  Bit Score: 108.40  E-value: 1.28e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  5 LVWVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKF 84
Cdd:PRK06161   2 LAWAILIAQVALALAMLLALWRLLRGPRAQDRILALDTLYINAILLLLVFGIRLGSTIYFEAALLIALLGFVSTVALAKF 81


                 ....*...
gi 1754900487 85 LLRGEVIE 92
Cdd:PRK06161  82 LLRGEVIE 89
MnhF COG2212
Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];
4-87 9.06e-20

Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441814  Cd Length: 84  Bit Score: 75.53  E-value: 9.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  4 WLVWVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAK 83
Cdd:COG2212    1 MMTTVLLIALALLALALLLALYRLIRGPTLADRVLALDTLGTNAVALLALLGILTGRPLYLDVALVLALLGFVGTVAFAR 80


                 ....
gi 1754900487 84 FLLR 87
Cdd:COG2212   81 FLER 84
PRK12600 PRK12600
Na(+)/H(+) antiporter subunit F1;
8-92 2.41e-13

Na(+)/H(+) antiporter subunit F1;


Pssm-ID: 183617  Cd Length: 94  Bit Score: 59.56  E-value: 2.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  8 VLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKFLLR 87
Cdd:PRK12600   5 ILSIALIIVAISMLLMLIRVIKGPTLADRVVALDAIGINLIAIIALFSILLDTKAYLEVILLIGILAFIGTAAFSKFIEK 84


                 ....*
gi 1754900487 88 GEVIE 92
Cdd:PRK12600  85 GKVIE 89
PRK12599 PRK12599
putative monovalent cation/H+ antiporter subunit F; Reviewed
 4-92 3.66e-11

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 237148  Cd Length: 91  Bit Score: 54.14  E-value: 3.66e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  4 WLVWVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAK 83
Cdd:PRK12599   3 LLEDAFLIAAVLLVLALILSLYRVILGPTLPDRVVALDTLNTITVGIIAVLAAATGRPLYLDIAIVYALLSFLGTVAIAK 82


                 ....*....
gi 1754900487 84 FLLRGEVIE 92
Cdd:PRK12599  83 YLVGRGGVL 91
MrpF_PhaF pfam04066
Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF ...
 35-86 2.18e-09

Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF family are predicted to be an integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation. It is also involved in symbiosis in Rhizobium meliloti. MrpF is part of a Na+/H+ antiporter complex, also involved in pH homeostasis. MrpF is thought to be an efflux system for Na+ and cholate. The Mrp system in Bacilli may also have primary energization capacities.


Pssm-ID: 461156  Cd Length: 52  Bit Score: 48.55  E-value: 2.18e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1754900487 35 DRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKFLL 86
Cdd:pfam04066  1 DRVVALDTLGTNIVALLALLAILTGRPAYLDVALVLALLGFVGTVAFARFLE 52
PRK12657 PRK12657
putative monovalent cation/H+ antiporter subunit F; Reviewed
 7-92 4.15e-07

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 183657  Cd Length: 100  Bit Score: 43.98  E-value: 4.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487   7 WVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKFLL 86
Cdd:PRK12657    8 IMIISALIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSVSISRFIG 87


                  ....*.
gi 1754900487  87 RGEVIE 92
Cdd:PRK12657   88 GGHVFN 93
PRK07948 PRK07948
putative monovalent cation/H+ antiporter subunit F; Reviewed
 7-84 2.08e-05

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 181179  Cd Length: 86  Bit Score: 39.29  E-value: 2.08e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1754900487  7 WVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKF 84
Cdd:PRK07948   3 VVLTIAAVFLSLAAILTTYRILAGPNSLDRLVALDTLVAVTMCALATWAAWTLDTTVTNAMTALALIGFIGSVSVARF 80
PRK12604 PRK12604
putative monovalent cation/H+ antiporter subunit F; Reviewed
 9-85 1.05e-03

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 183619  Cd Length: 84  Bit Score: 34.74  E-value: 1.05e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1754900487  9 LSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKFL 85
Cdd:PRK12604   4 INIYLALIAIATLLSMYRVFRGPTTVDRLVAVDIMTTITTGLMVLFALYYKRMIFLDVALVYAILAFVGVIAFARYL 80
PRK12612 PRK12612
putative monovalent cation/H+ antiporter subunit F; Reviewed
 5-88 1.40e-03

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 237151  Cd Length: 87  Bit Score: 34.52  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1754900487  5 LVWVLSVALFMLVLAMSFTLVRLYRGPSAQDRVLALDCMYLNGMLAMLVLGILYGSSMYFEAALLIALFGCVGSTAMAKF 84
Cdd:PRK12612   2 LLIISEIFLIIILLVILLALVLIIRTKDILTRLVISDMVFYAMALILLCLGLYNGTSIYYDIALAAGLLGFLGTIAYARI 81


                 ....
gi 1754900487 85 LLRG 88
Cdd:PRK12612  82 ISGG 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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