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Conserved domains on  [gi|1755457572|gb|KAB1055537|]
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GNAT family acetyltransferase [Cronobacter sakazakii]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11480005)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate; such as acetyltransferase YpeA

EC:  2.3.1.-
Gene Ontology:  GO:0008080
PubMed:  10940244

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK03624 PRK03624
putative acetyltransferase; Provisional
 35-174 6.83e-99

putative acetyltransferase; Provisional


:

Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 281.43  E-value: 6.83e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  35 NTMEIRVFRQADFEEVITLWERCDLLRSWNDPEMDIERKLNHDPDLFLVAEVSGEIVGSIMGGYDGHRGSAYYLGVHPEF 114
Cdd:PRK03624    1 DAMEIRVFRQADFEAVIALWERCDLTRPWNDPEMDIERKLNHDPSLFLVAEVGGEVVGTVMGGYDGHRGWAYYLAVHPDF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572 115 RGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDVISLGKRLIED 174
Cdd:PRK03624   81 RGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYEEQDRISLGKRLIED 140
 
Name Accession Description Interval E-value
PRK03624 PRK03624
putative acetyltransferase; Provisional
 35-174 6.83e-99

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 281.43  E-value: 6.83e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  35 NTMEIRVFRQADFEEVITLWERCDLLRSWNDPEMDIERKLNHDPDLFLVAEVSGEIVGSIMGGYDGHRGSAYYLGVHPEF 114
Cdd:PRK03624    1 DAMEIRVFRQADFEAVIALWERCDLTRPWNDPEMDIERKLNHDPSLFLVAEVGGEVVGTVMGGYDGHRGWAYYLAVHPDF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572 115 RGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDVISLGKRLIED 174
Cdd:PRK03624   81 RGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYEEQDRISLGKRLIED 140
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
36-165 1.29e-20

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 83.12  E-value: 1.29e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  36 TMEIRVFRQADFEEVITLWERCDL--LRSWNDPEMDIE------RKLNHDPDLFLVAEVSGEIVG----SIMGGYDGHRG 103
Cdd:COG1247     1 EMTIRPATPEDAPAIAAIYNEAIAegTATFETEPPSEEereawfAAILAPGRPVLVAEEDGEVVGfaslGPFRPRPAYRG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1755457572 104 SAYY-LGVHPEFRGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDVI 165
Cdd:COG1247    81 TAEEsIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGTL 143
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 54-159 9.95e-20

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 79.87  E-value: 9.95e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  54 WERCDLLRSWNDPEMDIERKLNHDP-DLFLVAEVSGEIVGSIMGGYDGHRGSAYYLG---VHPEFRGRGIANALLNRLEK 129
Cdd:pfam00583   7 LLSEEFPEPWPDEPLDLLEDWDEDAsEGFFVAEEDGELVGFASLSIIDDEPPVGEIEglaVAPEYRGKGIGTALLQALLE 86

                          90       100       110
                  ....*....|....*....|....*....|
gi 1755457572 130 KLIARGCPKINIQIREENDVVLGMYERLGY 159
Cdd:pfam00583  87 WARERGCERIFLEVAADNLAAIALYEKLGF 116
rimI TIGR01575
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ...
 62-166 1.95e-14

ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273701 [Multi-domain]  Cd Length: 131  Bit Score: 66.20  E-value: 1.95e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  62 SWNdpEMDIERKLNHDPDLFLVAEVSGEIVGSIMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPKINI 141
Cdd:TIGR01575  16 PWT--EAQFAEELANYHLCYLLARIGGKVVGYAGVQIVLDEAHILNIAVKPEYQGQGIGRALLRELIDEAKGRGVNEIFL 93

                          90       100
                  ....*....|....*....|....*
gi 1755457572 142 QIREENDVVLGMYERLGYEHQDVIS 166
Cdd:TIGR01575  94 EVRVSNIAAQALYKKLGFNEIAIRR 118
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 81-139 6.05e-12

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 58.06  E-value: 6.05e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1755457572  81 FLVAEVSGEIVGSIMGGYDGHRGSAYY---LGVHPEFRGRGIANALLNRLEKKLIARGCPKI 139
Cdd:cd04301     1 FLVAEDDGEIVGFASLSPDGSGGDTAYigdLAVLPEYRGKGIGSALLEAAEEEARERGAKRL 62
 
Name Accession Description Interval E-value
PRK03624 PRK03624
putative acetyltransferase; Provisional
 35-174 6.83e-99

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 281.43  E-value: 6.83e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  35 NTMEIRVFRQADFEEVITLWERCDLLRSWNDPEMDIERKLNHDPDLFLVAEVSGEIVGSIMGGYDGHRGSAYYLGVHPEF 114
Cdd:PRK03624    1 DAMEIRVFRQADFEAVIALWERCDLTRPWNDPEMDIERKLNHDPSLFLVAEVGGEVVGTVMGGYDGHRGWAYYLAVHPDF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572 115 RGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDVISLGKRLIED 174
Cdd:PRK03624   81 RGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYEEQDRISLGKRLIED 140
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
36-165 1.29e-20

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 83.12  E-value: 1.29e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  36 TMEIRVFRQADFEEVITLWERCDL--LRSWNDPEMDIE------RKLNHDPDLFLVAEVSGEIVG----SIMGGYDGHRG 103
Cdd:COG1247     1 EMTIRPATPEDAPAIAAIYNEAIAegTATFETEPPSEEereawfAAILAPGRPVLVAEEDGEVVGfaslGPFRPRPAYRG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1755457572 104 SAYY-LGVHPEFRGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDVI 165
Cdd:COG1247    81 TAEEsIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGTL 143
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 54-159 9.95e-20

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 79.87  E-value: 9.95e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  54 WERCDLLRSWNDPEMDIERKLNHDP-DLFLVAEVSGEIVGSIMGGYDGHRGSAYYLG---VHPEFRGRGIANALLNRLEK 129
Cdd:pfam00583   7 LLSEEFPEPWPDEPLDLLEDWDEDAsEGFFVAEEDGELVGFASLSIIDDEPPVGEIEglaVAPEYRGKGIGTALLQALLE 86

                          90       100       110
                  ....*....|....*....|....*....|
gi 1755457572 130 KLIARGCPKINIQIREENDVVLGMYERLGY 159
Cdd:pfam00583  87 WARERGCERIFLEVAADNLAAIALYEKLGF 116
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
39-161 2.15e-18

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 77.05  E-value: 2.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  39 IRVFRQADFEEVITLWERCdllrsWNDP-EMDIERKLNHDPD--LFLVAEVSGEIVGSIMG--GYDGHRGSAYYLG---V 110
Cdd:COG3153     1 IRPATPEDAEAIAALLRAA-----FGPGrEAELVDRLREDPAagLSLVAEDDGEIVGHVALspVDIDGEGPALLLGplaV 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1755457572 111 HPEFRGRGIANALLNRLEKKLIARGCPKINIqirEENDVVLGMYERLGYEH 161
Cdd:COG3153    76 DPEYRGQGIGRALMRAALEAARERGARAVVL---LGDPSLLPFYERFGFRP 123
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 92-165 7.19e-16

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 68.91  E-value: 7.19e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1755457572  92 GSIMGGYDGHRGSAY--YLGVHPEFRGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDVI 165
Cdd:COG0456     1 GFALLGLVDGGDEAEieDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEEVGER 76
rimI TIGR01575
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ...
 62-166 1.95e-14

ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273701 [Multi-domain]  Cd Length: 131  Bit Score: 66.20  E-value: 1.95e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  62 SWNdpEMDIERKLNHDPDLFLVAEVSGEIVGSIMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPKINI 141
Cdd:TIGR01575  16 PWT--EAQFAEELANYHLCYLLARIGGKVVGYAGVQIVLDEAHILNIAVKPEYQGQGIGRALLRELIDEAKGRGVNEIFL 93

                          90       100
                  ....*....|....*....|....*
gi 1755457572 142 QIREENDVVLGMYERLGYEHQDVIS 166
Cdd:TIGR01575  94 EVRVSNIAAQALYKKLGFNEIAIRR 118
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 77-160 2.28e-14

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 64.78  E-value: 2.28e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  77 DPDLFLVAEVSGEIVGSIMGGYDGHRGSAYYLG--VHPEFRGRGIANALLNRLEKKLIARGCPKINIQIREENdvvLGMY 154
Cdd:pfam13508   1 PGGRFFVAEDDGKIVGFAALLPLDDEGALAELRlaVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRA---AAFY 77


                  ....*.
gi 1755457572 155 ERLGYE 160
Cdd:pfam13508  78 EKLGFE 83
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 37-167 2.57e-14

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 66.17  E-value: 2.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  37 MEIRVFRQADFEEVITLWERCDLLRSWNDpemdierklnhdpdlFLVAEVSGEIVGsiMGGYDGHRGSAYYLG---VHPE 113
Cdd:COG1246     1 MTIRPATPDDVPAILELIRPYALEEEIGE---------------FWVAEEDGEIVG--CAALHPLDEDLAELRslaVHPD 63

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1755457572 114 FRGRGIANALLNRLEKKLIARGCPKIniqIREENDVVLGMYERLGYEHQDVISL 167
Cdd:COG1246    64 YRGRGIGRRLLEALLAEARELGLKRL---FLLTTSAAIHFYEKLGFEEIDKEDL 114
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
89-161 2.99e-12

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 59.15  E-value: 2.99e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1755457572  89 EIVGsiMGGYDGHRGSAYYLG---VHPEFRGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEH 161
Cdd:COG3393     1 ELVA--MAGVRAESPGVAEISgvyTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGFRP 74
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 81-139 6.05e-12

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 58.06  E-value: 6.05e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1755457572  81 FLVAEVSGEIVGSIMGGYDGHRGSAYY---LGVHPEFRGRGIANALLNRLEKKLIARGCPKI 139
Cdd:cd04301     1 FLVAEDDGEIVGFASLSPDGSGGDTAYigdLAVLPEYRGKGIGSALLEAAEEEARERGAKRL 62
Eis COG4552
Predicted acetyltransferase [General function prediction only];
37-161 2.13e-10

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443616 [Multi-domain]  Cd Length: 393  Bit Score: 58.37  E-value: 2.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  37 MEIRVFRQADFEEVITLWERCdLLRSWNDPEMDIERKLnHDPDLFLVAEVSGEIVGSiMGGYDGH---RGSAY------Y 107
Cdd:COG4552     1 MEIRPLTEDDLDAFARLLAYA-FGPEPDDEELEAYRPL-LEPGRVLGVFDDGELVGT-LALYPFTlnvGGARVpmagitG 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1755457572 108 LGVHPEFRGRGIANALLNRLEKKLIARGCPkIniqireendVVL-----GMYERLGYEH 161
Cdd:COG4552    78 VAVAPEHRRRGVARALLREALAELRERGQP-L---------SALypfepGFYRRFGYEL 126
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 42-165 1.03e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 53.90  E-value: 1.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  42 FRQADFEEVITLWERCDLlrswnDPEMDIERKLNHDpDLFLVAEVSGEIVG----SIMGGYDGHRGSAYylgVHPEFRGR 117
Cdd:COG0454     3 IRKATPEDINFILLIEAL-----DAELKAMEGSLAG-AEFIAVDDKGEPIGfaglRRLDDKVLELKRLY---VLPEYRGK 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1755457572 118 GIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDVI 165
Cdd:COG0454    74 GIGKALLEALLEWARERGCTALELDTLDGNPAAIRFYERLGFKEIERY 121
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 33-161 1.85e-08

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 51.15  E-value: 1.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  33 TGNTMEIRVFRQADFEEVITLWERCDLLRSWNDPEMDIE----------RKLNHDPDLFLVAE--VSGEIVGSI-MGGYD 99
Cdd:COG1670     4 ETERLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEearawlerllADWADGGALPFAIEdkEDGELIGVVgLYDID 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1755457572 100 GHRGSAYY-LGVHPEFRGRGIANALLNRLEKKLIAR-GCPKINIQIREENDVVLGMYERLGYEH 161
Cdd:COG1670    84 RANRSAEIgYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGFRL 147
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 80-160 8.20e-08

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 48.81  E-value: 8.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  80 LFLVAEVSGEIVGSIMGGYDGHrgsAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPKINIQIREENDVVlGMYERLGY 159
Cdd:pfam13673  32 FFFVAFEGGQIVGVIALRDRGH---ISLLFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSELTVNASPYAV-PFYEKLGF 107


                  .
gi 1755457572 160 E 160
Cdd:pfam13673 108 R 108
Acetyltransf_9 pfam13527
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 39-161 2.42e-07

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 404421 [Multi-domain]  Cd Length: 124  Bit Score: 47.18  E-value: 2.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  39 IRVFRQADFEEVITLWERCdLLRSwNDPEMDIERKLNHDPDLFLVAEVSGEIVGSIMGgYD------GHRGSAYYLG--- 109
Cdd:pfam13527   1 IRPLTEDEFDEVLRLLEYA-FQDE-DSPELREYFRPLLEEGRVLGAFDDGELVSTLAL-YPfelnvpGKTLPAAGITgva 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1755457572 110 VHPEFRGRGIANALLNRLEKKLIARGCPkiniqireendVVLGM------YERLGYEH 161
Cdd:pfam13527  78 TYPEYRGRGVMSRLLRRSLEEMRERGVP-----------LSFLYpssypiYRRFGYEI 124
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
65-160 2.70e-07

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 47.49  E-value: 2.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  65 DPEMDierklNHDPD-LFLVAEVSGEIVG--SIMGGYDGHrgsaYYLG---VHPEFRGRGIANALLNRLEKKLIARGCPK 138
Cdd:COG2153    24 YLELD-----GKDEDaRHLLAYDDGELVAtaRLLPPGDGE----AKIGrvaVLPEYRGQGLGRALMEAAIEEARERGARR 94

                          90       100
                  ....*....|....*....|..
gi 1755457572 139 INIQIREEndvVLGMYERLGYE 160
Cdd:COG2153    95 IVLSAQAH---AVGFYEKLGFV 113
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 110-164 3.33e-05

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 41.84  E-value: 3.33e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1755457572 110 VHPEFRGRGIANALLNRLEKKLIARGCPKINIQIREENDVVLGMYERLGYEHQDV 164
Cdd:PRK09491   71 VDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFNEVTI 125
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 88-160 3.82e-05

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 40.39  E-value: 3.82e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1755457572  88 GEIVGSIMGGYDGHRGSAYylgVHPEFRGRGIANALLNRLEKKLIARGcPKINIQIREENDVVLGMYERLGYE 160
Cdd:pfam08445  10 GELAAWCLRLPGGELGALQ---TLPEHRRRGLGSRLVAALARGIAERG-ITPFAVVVAGNTPSRRLYEKLGFR 78
Acetyltransf_6 pfam13480
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 38-136 6.32e-05

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions.


Pssm-ID: 433244 [Multi-domain]  Cd Length: 143  Bit Score: 41.11  E-value: 6.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  38 EIRVFRQADFEEVITLWERcdLLRSWNDPEMDIE---------RKLNHDPD-----LFLVAEVSGEIVGSIMGGYDGHRG 103
Cdd:pfam13480  19 GLRFEVATDPEDLDALLDL--KRAQWARRLPDLFappwtraflRDLLAALAargalRLYVLRLDGRPVAALLGLRSGDRL 96

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1755457572 104 SAYYLGVHPEFRGRGIANALLNRLEKKLIARGC 136
Cdd:pfam13480  97 YYWFGGYDPEYARLSPGLLLLWELIEHAAEEGL 129
COG3375 COG3375
Predicted acetyltransferase, GNAT superfamily [General function prediction only];
45-123 1.39e-03

Predicted acetyltransferase, GNAT superfamily [General function prediction only];


Pssm-ID: 442602 [Multi-domain]  Cd Length: 271  Bit Score: 38.00  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1755457572  45 ADFEEVItlwercDLLRS-WNDPEM-----DIERKLNHDPDLFLVAEVSGEIVGSIMG--GYDGHRGSAY--YLGVHPEF 114
Cdd:COG3375    14 AELEAVQ------RLQRSvWGSPPNepvpvHLLRALAHAGGYVLGAFDGGELVGFSFGfpGFRPGGLYLHshMAGVLPEY 87


                  ....*....
gi 1755457572 115 RGRGIANAL 123
Cdd:COG3375    88 RGRGVGYAL 96
PTZ00330 PTZ00330
acetyltransferase; Provisional
 110-160 3.07e-03

acetyltransferase; Provisional


Pssm-ID: 140351 [Multi-domain]  Cd Length: 147  Bit Score: 36.36  E-value: 3.07e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1755457572 110 VHPEFRGRGIANALLNRLEKKLIARGCPKIniqIREENDVVLGMYERLGYE 160
Cdd:PTZ00330   90 VDPSYRGQGLGRALISDLCEIARSSGCYKV---ILDCTEDMVAFYKKLGFR 137
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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