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Conserved domains on  [gi|1756894684|gb|KAB1491915|]
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2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [Cronobacter sakazakii]

Protein Classification

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase( domain architecture ID 10012990)

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 26-391 0e+00

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


:

Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 698.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPPDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFSADELQLPEL 105
Cdd:PRK08020   26 QHGFSVAVLEHAAPAPFDADSQPDVRISAISAASVALLKGLGVWDAVQAMRSHPYRRLETWEWETAHVVFDAAELKLPEL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 106 GYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQ 185
Cdd:PRK08020  106 GYMVENRVLQLALWQALEAHPNVTLRCPASLQALQRDDDGWELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYR 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 186 QSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVAC 265
Cdd:PRK08020  186 QSCMLISVKCENPPGDSTWQQFTPSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHFPARLGAVTPVAA 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 266 GAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLLM 345
Cdd:PRK08020  266 GAFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLLM 345

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 1756894684 346 QSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK08020  346 QSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYALGL 391
 
Name Accession Description Interval E-value
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 26-391 0e+00

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 698.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPPDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFSADELQLPEL 105
Cdd:PRK08020   26 QHGFSVAVLEHAAPAPFDADSQPDVRISAISAASVALLKGLGVWDAVQAMRSHPYRRLETWEWETAHVVFDAAELKLPEL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 106 GYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQ 185
Cdd:PRK08020  106 GYMVENRVLQLALWQALEAHPNVTLRCPASLQALQRDDDGWELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYR 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 186 QSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVAC 265
Cdd:PRK08020  186 QSCMLISVKCENPPGDSTWQQFTPSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHFPARLGAVTPVAA 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 266 GAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLLM 345
Cdd:PRK08020  266 GAFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLLM 345

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 1756894684 346 QSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK08020  346 QSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYALGL 391
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 26-390 9.66e-149

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 426.23  E-value: 9.66e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPpDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWN-EARVEFSADELQLPE 104
Cdd:TIGR01988  20 RSGLKVALIEATPLPAPADPGF-DNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDGGsFGALRFDADEIGLEA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 105 LGYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQY 184
Cdd:TIGR01988  99 LGYVVENRVLQQALWERLQELPNVTLLCPARVVELPRHSDHVELTLDDGQQLRARLLVGADGANSKVRQLAGIPTTGWDY 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 185 QQSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPV- 263
Cdd:TIGR01988 179 GQSAVVANVKHERPHQGTAWERFTPTGPLALLPLPDNRSSLVWTLPPEEAERLLALSDEEFLAELQRAFGSRLGAITLVg 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 264 ACGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNL 343
Cdd:TIGR01988 259 ERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNA 338

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1756894684 344 LMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALG 390
Cdd:TIGR01988 339 AMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 26-386 1.24e-67

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 216.73  E-value: 1.24e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFspqnppDVRISSISCASVDLLRGLGVWQRVLEmRAHPYRRLETWEWNEARV--EFSADELQLP 103
Cdd:COG0654    24 RAGIRVTVVERAPPPRP------DGRGIALSPRSLELLRRLGLWDRLLA-RGAPIRGIRVRDGSDGRVlaRFDAAETGLP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 104 ElGYMVENSVLQRALWEALEAHPaVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQ 183
Cdd:COG0654    97 A-GLVVPRADLERALLEAARALG-VELRFGTEVTGLEQDADGVTVTLADGRTLRADLVVGADGARSAVRRLLGIGFTGRD 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 184 YQQSCLLISVECEqppgdstwqhftpngphaflplfdnraslvwydrparvrqlqamsmtqLGREIAAAFPaRLGRVTPV 263
Cdd:COG0654   175 YPQRALWAGVRTE------------------------------------------------LRARLAAAGP-RLGELLEL 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 264 A-CGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNaaeDWASGAVLKRYQRRRMPDN 342
Cdd:COG0654   206 SpRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALR---GRDDEAALARYERERRPRA 282

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1756894684 343 LLMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALR 386
Cdd:COG0654   283 ARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKGGGLP 326
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 55-340 1.87e-13

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 70.82  E-value: 1.87e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  55 ISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFsaDELQLPELGYMVENSVLQRALWEALEAHPAvQLLCPA 134
Cdd:pfam01494  45 LNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRRRADL--DFLTSPPRVTVYPQTELEPILVEHAEARGA-QVRFGT 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 135 TLTQMTPVQNGYQLSLTNGD-----TLQARLVIGADGASSQVRKWAGIGVNAWQYQQScLLISVECEQPP--------GD 201
Cdd:pfam01494 122 EVLSLEQDGDGVTAVVRDRRdgeeyTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPF-GSLDVLFDAPDlsdpveraFV 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 202 STWQHFTPNGPHAFLPLFDnraslvwYDRPARVRQLQAMsmTQLGREIAAAFPARLGRVTPVACG------------AFP 269
Cdd:pfam01494 201 HYLIYAPHSRGFMVGPWRS-------AGRERYYVQVPWD--EEVEERPEEFTDEELKQRLRSIVGidlalveilwksIWG 271

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1756894684 270 LVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDAL---LKVVIdarnaaEDWASGAVLKRYQRRRMP 340
Cdd:pfam01494 272 VASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLawkLAAVL------RGQAGESLLDTYSAERLP 339
 
Name Accession Description Interval E-value
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 26-391 0e+00

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 698.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPPDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFSADELQLPEL 105
Cdd:PRK08020   26 QHGFSVAVLEHAAPAPFDADSQPDVRISAISAASVALLKGLGVWDAVQAMRSHPYRRLETWEWETAHVVFDAAELKLPEL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 106 GYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQ 185
Cdd:PRK08020  106 GYMVENRVLQLALWQALEAHPNVTLRCPASLQALQRDDDGWELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYR 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 186 QSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVAC 265
Cdd:PRK08020  186 QSCMLISVKCENPPGDSTWQQFTPSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHFPARLGAVTPVAA 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 266 GAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLLM 345
Cdd:PRK08020  266 GAFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLLM 345

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 1756894684 346 QSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK08020  346 QSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYALGL 391
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 26-391 1.19e-157

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 448.84  E-value: 1.19e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPPDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFSADELQLPEL 105
Cdd:PRK08849   24 KQGRSVAVIEGGEPKAFEPSQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKRLETWEHPECRTRFHSDELNLDQL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 106 GYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQ 185
Cdd:PRK08849  104 GYIVENRLIQLGLWQQFAQYPNLTLMCPEKLADLEFSAEGNRVTLESGAEIEAKWVIGADGANSQVRQLAGIGITAWDYR 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 186 QSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVAC 265
Cdd:PRK08849  184 QHCMLINVETEQPQQDITWQQFTPSGPRSFLPLCGNQGSLVWYDSPKRIKQLSAMNPEQLRSEILRHFPAELGEIKVLQH 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 266 GAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVidarnAAEDWASGAVLKRYQRRRMPDNLLM 345
Cdd:PRK08849  264 GSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVLLAET-----EKQGVLNDASFARYERRRRPDNLLM 338

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 1756894684 346 QSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK08849  339 QTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKYALGM 384
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 26-390 9.66e-149

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 426.23  E-value: 9.66e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPpDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWN-EARVEFSADELQLPE 104
Cdd:TIGR01988  20 RSGLKVALIEATPLPAPADPGF-DNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDGGsFGALRFDADEIGLEA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 105 LGYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQY 184
Cdd:TIGR01988  99 LGYVVENRVLQQALWERLQELPNVTLLCPARVVELPRHSDHVELTLDDGQQLRARLLVGADGANSKVRQLAGIPTTGWDY 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 185 QQSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPV- 263
Cdd:TIGR01988 179 GQSAVVANVKHERPHQGTAWERFTPTGPLALLPLPDNRSSLVWTLPPEEAERLLALSDEEFLAELQRAFGSRLGAITLVg 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 264 ACGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNL 343
Cdd:TIGR01988 259 ERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNA 338

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1756894684 344 LMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALG 390
Cdd:TIGR01988 339 AMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
26-390 5.74e-93

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 284.15  E-value: 5.74e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPpDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFSADELQLPEL 105
Cdd:PRK07608   26 QSGLRVALLAPRAPPRPADDAW-DSRVYAISPSSQAFLERLGVWQALDAARLAPVYDMRVFGDAHARLHFSAYQAGVPQL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 106 GYMVENSVLQRALWEALEAHPAVQLLcPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQ 185
Cdd:PRK07608  105 AWIVESSLIERALWAALRFQPNLTWF-PARAQGLEVDPDAATLTLADGQVLRADLVVGADGAHSWVRSQAGIKAERRPYR 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 186 QSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGR---VTP 262
Cdd:PRK07608  184 QTGVVANFKAERPHRGTAYQWFRDDGILALLPLPDGHVSMVWSARTAHADELLALSPEALAARVERASGGRLGRlecVTP 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 263 VAcgAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKvVIDARNAAEDWASGAVLKRYQRRRMPDN 342
Cdd:PRK07608  264 AA--GFPLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALAD-VLAGREPFRDLGDLRLLRRYERARREDI 340

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1756894684 343 LLMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALG 390
Cdd:PRK07608  341 LALQVATDGLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHALG 388
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 51-383 8.88e-87

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 269.70  E-value: 8.88e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  51 RISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWN-EARVEFSADELQlPELGYMVENSVLQRALWEALEAHPA-- 127
Cdd:TIGR01989  56 RVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDGCsLALIRFDRDNGK-EDMACIIENDNIQNSLYNRLQEYNGdn 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 128 VQLLCPA-----TLTQMTPVQNGY--QLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPPG 200
Cdd:TIGR01989 135 VKILNPArlisvTIPSKYPNDNSNwvHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATE 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 201 DST-WQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAF----------------PARL------ 257
Cdd:TIGR01989 215 NDVaWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFdlgysdhpysylldyaMEKLnedigf 294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 258 --------GRVTPVACG-------AFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAA 322
Cdd:TIGR01989 295 rtegskscFQVPPRVIGvvdksraAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVG 374

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1756894684 323 EDWASGAVLKRYQRRRMPDNLLMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQ 383
Cdd:TIGR01989 375 ADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNF 435
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 31-390 1.46e-85

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 264.95  E-value: 1.46e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  31 VAVVEHAAPPPFSPQNppDVRISSISCASVDLLRGLGVWQRvLEMRAHPYRRLETWEWNEA-RVEFSADELQLPELGYMV 109
Cdd:TIGR01984  26 IALIEANSPSAAQPGF--DARSLALSYGSKQILEKLGLWPK-LAPFATPILDIHVSDQGHFgATHLRASEFGLPALGYVV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 110 ENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCL 189
Cdd:TIGR01984 103 ELADLGQALLSRLALLTNIQLYCPARYKEIIRNQDYVRVTLDNGQQLRAKLLIAADGANSKVRELLSIPTEEHDYNQTAL 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 190 LISVECEQPPGDSTWQHFTPNGPHAFLPLFDN-RASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVACG-A 267
Cdd:TIGR01984 183 IANIRHEQPHQGCAFERFTPHGPLALLPLKDNyRSSLVWCLPSKQADTIANLPDAEFLAELQQAFGWRLGKITQVGERkT 262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 268 FPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARnaaEDWASGAVLKRYQRRRMPDNLLMQS 347
Cdd:TIGR01984 263 YPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVLIDAR---IDLGTYALLQEYLRRRQFDQFITIG 339

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 1756894684 348 GMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALG 390
Cdd:TIGR01984 340 LTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQAMG 382
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 51-391 1.31e-84

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 263.23  E-value: 1.31e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  51 RISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWN-EARVEFSADELQLPELGYMVENSVLQRALWEALeAHPAVQ 129
Cdd:PRK05714   50 RVSALSAASQRILERLGAWDGIAARRASPYSEMQVWDGSgTGQIHFSAASVHAEVLGHIVENRVVQDALLERL-HDSDIG 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 130 LLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPPGDSTWQHFTP 209
Cdd:PRK05714  129 LLANARLEQMRRSGDDWLLTLADGRQLRAPLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEPHRATAWQRFTD 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 210 NGPHAFLPLFDNR----ASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVT---PVACgaFPLVRRHALRYVLPG 282
Cdd:PRK05714  209 DGPLAFLPLERDGdehwCSIVWSTTPEEAERLMALDDDAFCAALERAFEGRLGEVLsadPRLC--VPLRQRHAKRYVEPG 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 283 VALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLLMQSGMDLFHAGFTAKLKP 362
Cdd:PRK05714  287 LALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLP 366

                         330       340
                  ....*....|....*....|....*....
gi 1756894684 363 LRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK05714  367 LRWLRNTGLKLVDQMPEAKALFVRQALGL 395
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 28-391 2.88e-82

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 257.01  E-value: 2.88e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  28 GFQVAVVEHAAPPPFSPQNPpDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNE-ARVEFSADELQLPELG 106
Cdd:PRK08850   27 DLRIAVIEGQLPEEALNELP-DVRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSfARIEFDAESMAQPDLG 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 107 YMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQ 186
Cdd:PRK08850  106 HIVENRVIQLALLEQVQKQDNVTLLMPARCQSIAVGESEAWLTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGH 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 187 SCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFD-NRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPV-A 264
Cdd:PRK08850  186 SALVANVRTVDPHNSVARQIFTPQGPLAFLPMSEpNMSSIVWSTEPLRAEALLAMSDEQFNKALTAEFDNRLGLCEVVgE 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 265 CGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLL 344
Cdd:PRK08850  266 RQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAK 345

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1756894684 345 MQSGM----DLFHAGFTAKlkplRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK08850  346 MIAAMqgfrDLFSGSNPAK----KLVRGIGMSLAGQLPGAKDEIMKRALGL 392
PRK08013 PRK08013
oxidoreductase; Provisional
 28-391 1.16e-81

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 255.36  E-value: 1.16e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  28 GFQVAVVEHAAPPPFSPQNPPDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNE-ARVEFSADELQLPELG 106
Cdd:PRK08013   26 GLRVAVLEQRVPEPLAADAPPALRVSAINAASEKLLTRLGVWQDILARRASCYHGMEVWDKDSfGRIAFDDQSMGYSHLG 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 107 YMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQ 186
Cdd:PRK08013  106 HIIENSVIHYALWQKAQQSSDITLLAPAELQQVAWGENEAFLTLKDGSMLTARLVVGADGANSWLRNKADIPLTFWDYQH 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 187 SCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNR-ASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVA- 264
Cdd:PRK08013  186 HALVATIRTEEPHDAVARQVFHGDGILAFLPLSDPHlCSIVWSLSPEEAQRMQQAPEEEFNRALAIAFDNRLGLCELESe 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 265 CGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLL 344
Cdd:PRK08013  266 RQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSAAL 345

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1756894684 345 MQSGM----DLFHAGFTAKlkplRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK08013  346 MLAGMqgfrDLFAGNNPAK----KLLRDIGLKLADTLPGVKPQLIRQAMGL 392
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 26-391 3.97e-81

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 254.01  E-value: 3.97e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEhAAPPPFSPQNPPDVRISSISCASVDLLRGLGVWQRvLEMRAHPYRRLETWEWNEA-RVEFSADELQLPE 104
Cdd:PRK05732   27 HGGLPVALIE-AFAPESDAHPGFDARAIALAAGTCQQLARLGVWQA-LADCATPITHIHVSDRGHAgFVRLDAEDYGVPA 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 105 LGYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQY 184
Cdd:PRK05732  105 LGYVVELHDVGQRLFALLDKAPGVTLHCPARVANVERTQGSVRVTLDDGETLTGRLLVAADGSHSALREALGIDWQQHPY 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 185 QQSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPV- 263
Cdd:PRK05732  185 EQVAVIANVTTSEAHQGRAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSWSDAQFLAELQQAFGWRLGRITHAg 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 264 ACGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDnl 343
Cdd:PRK05732  265 KRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQQD-- 342

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1756894684 344 lmQSGMDLFHAG----FTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK05732  343 --REATIGFTDGlvrlFANRWAPLVVGRNLGLMAMDLLPPARDWLARRTLGW 392
PRK07364 PRK07364
FAD-dependent hydroxylase;
55-391 4.56e-78

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 246.47  E-value: 4.56e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  55 ISCASVDLLRGLGVWQRVLEmRAHPYRRLETWEWN-EARVEFSADELQLPELGYMVENSVLQRALWEALEAHPAVQLLCP 133
Cdd:PRK07364   64 LSLLSARIFEGIGVWEKILP-QIGKFRQIRLSDADyPGVVKFQPTDLGTEALGYVGEHQVLLEALQEFLQSCPNITWLCP 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 134 ATLTQMTPVQNGYQLSLTNGD---TLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPPGDSTWQHFTPN 210
Cdd:PRK07364  143 AEVVSVEYQQDAATVTLEIEGkqqTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAPHNDIAYERFWPS 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 211 GPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPV-ACGAFPLVRRHALRYVLPGVALIGDA 289
Cdd:PRK07364  223 GPFAILPLPGNRCQIVWTAPHAQAKALLALPEAEFLAELQQRYGDQLGKLELLgDRFLFPVQLMQSDRYVQHRLALVGDA 302

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 290 AHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLLMQSGMDLFHAGFTAKLKPLRVLRNL 369
Cdd:PRK07364  303 AHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRL 382

                         330       340
                  ....*....|....*....|..
gi 1756894684 370 GLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK07364  383 GLWLLRHVPPLKRLALRLMTGL 404
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
28-372 7.18e-74

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 235.14  E-value: 7.18e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  28 GFQVAVVEHAAPPPFSPQNPpDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWE-WNEARVEFSADELQLPELG 106
Cdd:PRK08773   29 GLSVALVEGREPPRWQADQP-DLRVYAFAADNAALLDRLGVWPAVRAARAQPYRRMRVWDaGGGGELGFDADTLGREQLG 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 107 YMVENSVLQRALWEALEAhPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQ 186
Cdd:PRK08773  108 WIVENDLLVDRLWAALHA-AGVQLHCPARVVALEQDADRVRLRLDDGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQ 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 187 SCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVAC- 265
Cdd:PRK08773  187 RGVVAFVDTEHPHQATAWQRFLPTGPLALLPFADGRSSIVWTLPDAEAERVLALDEAAFSRELTQAFAARLGEVRVASPr 266

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 266 GAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLLM 345
Cdd:PRK08773  267 TAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAAPHRLQRWARTRRSDNTVA 346

                         330       340
                  ....*....|....*....|....*....
gi 1756894684 346 QSGMDLFHAGFTAKLKPLRVLRN--LGLI 372
Cdd:PRK08773  347 AYGFDAINRVFSNDEMHLTLLRGsvLGLA 375
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 26-386 1.24e-67

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 216.73  E-value: 1.24e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFspqnppDVRISSISCASVDLLRGLGVWQRVLEmRAHPYRRLETWEWNEARV--EFSADELQLP 103
Cdd:COG0654    24 RAGIRVTVVERAPPPRP------DGRGIALSPRSLELLRRLGLWDRLLA-RGAPIRGIRVRDGSDGRVlaRFDAAETGLP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 104 ElGYMVENSVLQRALWEALEAHPaVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQ 183
Cdd:COG0654    97 A-GLVVPRADLERALLEAARALG-VELRFGTEVTGLEQDADGVTVTLADGRTLRADLVVGADGARSAVRRLLGIGFTGRD 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 184 YQQSCLLISVECEqppgdstwqhftpngphaflplfdnraslvwydrparvrqlqamsmtqLGREIAAAFPaRLGRVTPV 263
Cdd:COG0654   175 YPQRALWAGVRTE------------------------------------------------LRARLAAAGP-RLGELLEL 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 264 A-CGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNaaeDWASGAVLKRYQRRRMPDN 342
Cdd:COG0654   206 SpRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAALR---GRDDEAALARYERERRPRA 282

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1756894684 343 LLMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALR 386
Cdd:COG0654   283 ARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKGGGLP 326
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
49-391 1.66e-66

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 216.38  E-value: 1.66e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  49 DVRISSISCASVDLLRGLGVWQRVlEMRAHPYRRLETwewNEARVE---------FSADELQLPELGYMVENSVLQRALW 119
Cdd:PRK07333   43 DPRASAIAAAARRMLEALGVWDEI-APEAQPITDMVI---TDSRTSdpvrpvfltFEGEVEPGEPFAHMVENRVLINALR 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 120 EALEAHpAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPP 199
Cdd:PRK07333  119 KRAEAL-GIDLREATSVTDFETRDEGVTVTLSDGSVLEARLLVAADGARSKLRELAGIKTVGWDYGQSGIVCTVEHERPH 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 200 GDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPV-ACGAFPLVRRHALRY 278
Cdd:PRK07333  198 GGRAEEHFLPAGPFAILPLKGNRSSLVWTERTADAERLVALDDLVFEAELEQRFGHRLGELKVLgKRRAFPLGLTLARSF 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 279 VLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPDNLLMQSGMDLFHAGFTA 358
Cdd:PRK07333  278 VAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSN 357

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1756894684 359 KLKPLRVLRNLGLIAAQRSGVLKRQALRYALGL 391
Cdd:PRK07333  358 DSTLLRSVRDIGLGLVDRLPKLKSFFIRQAAGL 390
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
26-390 3.39e-56

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 188.96  E-value: 3.39e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPfspqnppDVRISSISCASVDLLRGLGVWQRvLEMRAHPYR--RL--ETWEWNEAR-VEFSADEL 100
Cdd:PRK07494   28 RAGASVALVAPEPPYA-------DLRTTALLGPSIRFLERLGLWAR-LAPHAAPLQsmRIvdATGRLIRAPeVRFRAAEI 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 101 QLPELGYMVENSVLQRALWEALEAHPAVQLlcPATLTQ-MTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGV 179
Cdd:PRK07494  100 GEDAFGYNIPNWLLNRALEARVAELPNITR--FGDEAEsVRPREDEVTVTLADGTTLSARLVVGADGRNSPVREAAGIGV 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 180 NAWQYQQSCLLISVECEQPPGD-STWQHfTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLG 258
Cdd:PRK07494  178 RTWSYPQKALVLNFTHSRPHQNvSTEFH-TEGGPFTQVPLPGRRSSLVWVVRPAEAERLLALSDAALSAAIEERMQSMLG 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 259 RVTpVACG--AFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVidaRNAAEDWASGAVLKRYQR 336
Cdd:PRK07494  257 KLT-LEPGrqAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLVEIV---EDRPEDPGSAAVLAAYDR 332

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1756894684 337 RRMPDNLLMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKRQALRYALG 390
Cdd:PRK07494  333 ARRPDILSRTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFMREGLG 386
PRK09126 PRK09126
FAD-dependent hydroxylase;
26-382 3.23e-54

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 183.99  E-value: 3.23e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  26 QNGFQVAVVEHAAPPPFSPQNPpDVRISSISCASVDLLRGLGVWQRVLEMRAHPYRrletwewnEARVE---------FS 96
Cdd:PRK09126   24 GSGLKVTLIERQPLAALADPAF-DGREIALTHASREILQRLGAWDRIPEDEISPLR--------DAKVLngrspfaltFD 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  97 ADELQLPELGYMVENSVLQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAG 176
Cdd:PRK09126   95 ARGRGADALGYLVPNHLIRRAAYEAVSQQDGIELLTGTRVTAVRTDDDGAQVTLANGRRLTARLLVAADSRFSATRRQLG 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 177 IGVNAWQYQQSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYDRPARVRQLQAMSMTQLGREIAAAFPAR 256
Cdd:PRK09126  175 IGADMHDFGRTMLVCRMRHELPHHHTAWEWFGYGQTLALLPLNGHLSSLVLTLPPDQIEALLALDPEAFAAEVTARFKGR 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 257 LGRVTPV-ACGAFPLVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQ 335
Cdd:PRK09126  255 LGAMRLVsSRHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAASLLERYE 334

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1756894684 336 RRRMPDNLLMQSGMDLFHAGFTAKLKPLRVLRNLGLIAAQRSGVLKR 382
Cdd:PRK09126  335 RKHRLATRPLYHATNAIAALYTDDRPPARLLRRAVLRAANRFPPLKQ 381
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
49-373 1.33e-35

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 134.43  E-value: 1.33e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  49 DVRISSISCASVDLLRGLGVWQRvlemRAHPYRRLETWEWNE-ARVEFSADELQLPELGYMVENSVLQRALWEALEAHPA 127
Cdd:PRK06996   55 DPRAIALSHGSRVLLETLGAWPA----DATPIEHIHVSQRGHfGRTLIDRDDHDVPALGYVVRYGSLVAALARAVRGTPV 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 128 VQLlcpATLTQMTPVQNGYQLSLTNGD-----TLQARLVIGADGA-SSQVRKWAGIGVNAWQYQQSCLLISVECEQPPGD 201
Cdd:PRK06996  131 RWL---TSTTAHAPAQDADGVTLALGTpqgarTLRARIAVQAEGGlFHDQKADAGDSARRRDYGQTAIVGTVTVSAPRPG 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 202 STWQHFTPNGPHAFLPLFDNRA---SLVWYDRPARVRQLQAMSMTQLGREIAAAFPARLGRVTPVAC-GAFPLVRRHALR 277
Cdd:PRK06996  208 WAWERFTHEGPLALLPLGGPRQadyALVWCCAPDEAARRAALPDDAFLAELGAAFGTRMGRFTRIAGrHAFPLGLNAART 287

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 278 YVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALlkvvidARNAAEDWASGAVLKRYQRRRMPDNLLMQSGMDLFHAGFT 357
Cdd:PRK06996  288 LVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTL------ADALSDHGATPLALATFAARRALDRRVTIGATDLLPRLFT 361

                         330
                  ....*....|....*.
gi 1756894684 358 AKLKPLRVLRNLGLIA 373
Cdd:PRK06996  362 VDSRPLAHLRGAALTA 377
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 49-390 2.18e-34

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 130.81  E-value: 2.18e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  49 DVRISSISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFSADELQLpeLGYMVENSVLQRALWEALEAHPAV 128
Cdd:PRK06617   43 DIRTTALTPHSKNFLFSIDIWEELEKFVAEMQDIYVVDNKASEILDLRNDADAV--LGYVVKNSDFKKILLSKITNNPLI 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 129 QLLcPATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQqSCLLISVECEQPPGDSTWQHFT 208
Cdd:PRK06617  121 TLI-DNNQYQEVISHNDYSIIKFDDKQIKCNLLIICDGANSKVRSHYFANEIEKPYQ-TALTFNIKHEKPHENCAMEHFL 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 209 PNGPHAFLPLFDNRAS-LVWY---DRPARVRQLQAMSMTQLGREIAAAFparLGRVT-PVACGAFPLVRRHALRYVLPGV 283
Cdd:PRK06617  199 PLGPFALLPLKDQYASsVIWStssDQAALIVNLPVEEVRFLTQRNAGNS---LGKITiDSEISSFPLKARIANRYFHNRI 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 284 ALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVidarnaaedwASGAVLKRYQRRRMPDNLLMQSGMDLFHAGFTAKLKPL 363
Cdd:PRK06617  276 VLIADTAHTVHPLAGQGLNQGIKDIEILSMIV----------SNNGTLQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNL 345

                         330       340
                  ....*....|....*....|....*..
gi 1756894684 364 RVLRNLGLIAAQRSGVLKRQALRYALG 390
Cdd:PRK06617  346 RCLRQIGFKVINNFKPIKNLITSYAMG 372
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
54-337 1.30e-16

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 79.24  E-value: 1.30e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  54 SISCASVDLLRGLGVWQRVlemrAHPYRRLETWEWNEARVEFSADelqlPELGYMVENSVLQRALWEALEAHpAVQLLCP 133
Cdd:COG0644    36 GLLPRALEELEPLGLDEPL----ERPVRGARFYSPGGKSVELPPG----RGGGYVVDRARFDRWLAEQAEEA-GAEVRTG 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 134 ATLTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPPG-----DSTWQHFT 208
Cdd:COG0644   107 TRVTDVLRDDGRVVVRTGDGEEIRADYVVDADGARSLLARKLGLKRRSDEPQDYALAIKEHWELPPLegvdpGAVEFFFG 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 209 PNGPHAFL---PLFDNRASLvwydrparvrqlqamsmtqlgrEIAAAFPARlgrvtpvacgafplvrrhalRYVLPGVAL 285
Cdd:COG0644   187 EGAPGGYGwvfPLGDGRVSV----------------------GIPLGGPRP--------------------RLVGDGVLL 224

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1756894684 286 IGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEdwASGAVLKRYQRR 337
Cdd:COG0644   225 VGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGGD--FSAEALAEYERR 274
PRK06834 PRK06834
hypothetical protein; Provisional
 144-386 3.72e-16

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 79.68  E-value: 3.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 144 NGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPPgdsTWQ-HFTPNGPHAFlplfdnr 222
Cdd:PRK06834  131 TGVDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEP---EWGvHRDALGIHAF------- 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 223 aSLVWYDRPARV----RQLQAM---SMTQLGREIAAAFPARLGRVTPVACGAFPLVRRHALRYVLPGVALIGDAAHTIHP 295
Cdd:PRK06834  201 -GRLEDEGPVRVmvteKQVGATgepTLDDLREALIAVYGTDYGIHSPTWISRFTDMARQAASYRDGRVLLAGDAAHVHSP 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 296 LAGQGVNLGyrdvdallkvVIDARNAAedWASGAVLKryqrRRMPDNLLmqsgmDLFHagftAKLKPL--RVLRN-LGLI 372
Cdd:PRK06834  280 VGGQGLNTG----------VQDAVNLG--WKLAQVVK----GTSPESLL-----DTYH----AERHPVaaRVLRNtMAQV 334

                         250
                  ....*....|....
gi 1756894684 373 AAQRSGVlKRQALR 386
Cdd:PRK06834  335 ALLRPDD-RTEALR 347
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
114-340 5.29e-14

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 73.40  E-value: 5.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 114 LQRALWEALEAHPAVQLLCPATLTQMTPVQNGYQLSLTNGD----TLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCL 189
Cdd:PRK06183  115 LEAVLRAGLARFPHVRVRFGHEVTALTQDDDGVTVTLTDADgqreTVRARYVVGCDGANSFVRRTLGVPFEDLTFPERWL 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 190 LISVECEQPP--GDSTWQHFTPNGPHAFLPLFDNR----------ASLVWYDRPARVRQLqamsmtqLGREIAAAFPARL 257
Cdd:PRK06183  195 VVDVLIANDPlgGPHTYQYCDPARPYTSVRLPHGRrrwefmllpgETEEQLASPENVWRL-------LAPWGPTPDDAEL 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 258 GRVTPVACGAfplvrRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDAL---LKVVIDARnaaedwASGAVLKRY 334
Cdd:PRK06183  268 IRHAVYTFHA-----RVADRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRDAANLawkLAAVLRGR------AGDALLDTY 336


                  ....*.
gi 1756894684 335 QRRRMP 340
Cdd:PRK06183  337 EQERRP 342
PRK07045 PRK07045
putative monooxygenase; Reviewed
 114-342 1.76e-13

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 71.09  E-value: 1.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 114 LQRALWEALEAHPAVQLLCPATLTQMTPVQNGY--QLSLTNGDTLQARLVIGADGASSQVRK-WAGIGVNAWQYQQSCLL 190
Cdd:PRK07045  108 LRRLLLAKLDGLPNVRLRFETSIERIERDADGTvtSVTLSDGERVAPTVLVGADGARSMIRDdVLRMPAERVPYATPMAF 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 191 ISV-------ECEQPPGDSTwqhftpNGPHAFLPLFDNRASLVW---------YDRPARVRQLQAMSMTQLGREIAAAFP 254
Cdd:PRK07045  188 GTIaltdsvrECNRLYVDSN------QGLAYFYPIGDQATRLVVsfpademqgYLADTTRTKLLARLNEFVGDESADAMA 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 255 ArlgrVTpvACGAFPLV---RRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDAL---LKVVIDARNAAEDwasg 328
Cdd:PRK07045  262 A----IG--AGTAFPLIplgRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELgacLDLHLSGQIALAD---- 331

                         250
                  ....*....|....
gi 1756894684 329 aVLKRYQRRRMPDN 342
Cdd:PRK07045  332 -ALERFERIRRPVN 344
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 55-340 1.87e-13

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 70.82  E-value: 1.87e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  55 ISCASVDLLRGLGVWQRVLEMRAHPYRRLETWEWNEARVEFsaDELQLPELGYMVENSVLQRALWEALEAHPAvQLLCPA 134
Cdd:pfam01494  45 LNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRRRADL--DFLTSPPRVTVYPQTELEPILVEHAEARGA-QVRFGT 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 135 TLTQMTPVQNGYQLSLTNGD-----TLQARLVIGADGASSQVRKWAGIGVNAWQYQQScLLISVECEQPP--------GD 201
Cdd:pfam01494 122 EVLSLEQDGDGVTAVVRDRRdgeeyTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPF-GSLDVLFDAPDlsdpveraFV 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 202 STWQHFTPNGPHAFLPLFDnraslvwYDRPARVRQLQAMsmTQLGREIAAAFPARLGRVTPVACG------------AFP 269
Cdd:pfam01494 201 HYLIYAPHSRGFMVGPWRS-------AGRERYYVQVPWD--EEVEERPEEFTDEELKQRLRSIVGidlalveilwksIWG 271

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1756894684 270 LVRRHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDAL---LKVVIdarnaaEDWASGAVLKRYQRRRMP 340
Cdd:pfam01494 272 VASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLawkLAAVL------RGQAGESLLDTYSAERLP 339
PRK06185 PRK06185
FAD-dependent oxidoreductase;
49-340 1.15e-11

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 65.65  E-value: 1.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  49 DVRISSISCASVDLLRGLGVWQRVLEmraHPYRRLETwewneARVEFSADELQLPELG---------YMVENSVLQRALW 119
Cdd:PRK06185   44 DFRGDTVHPSTLELMDELGLLERFLE---LPHQKVRT-----LRFEIGGRTVTLADFSrlptpypyiAMMPQWDFLDFLA 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 120 EALEAHPAVQLLCPATLTQMT----PVQnGYQLSLTNGD-TLQARLVIGADGASSQVRKWAGigvnawqyqqscllISVE 194
Cdd:PRK06185  116 EEASAYPNFTLRMGAEVTGLIeeggRVT-GVRARTPDGPgEIRADLVVGADGRHSRVRALAG--------------LEVR 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 195 CEQPPGDSTWqhF----TPNGPHAFLPLFDNRASLVWYDRPARVR-----------QLQAMSMTQLGREIAAAFPARLGR 259
Cdd:PRK06185  181 EFGAPMDVLW--FrlprEPDDPESLMGRFGPGQGLIMIDRGDYWQcgyvipkggyaALRAAGLEAFRERVAELAPELADR 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 260 VTPVAcgAFPLVR------RHALRYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDArnAAEDWASGAVLKR 333
Cdd:PRK06185  259 VAELK--SWDDVKlldvrvDRLRRWHRPGLLCIGDAAHAMSPVGGVGINLAIQDAVAAANILAEP--LRRGRVSDRDLAA 334


                  ....*..
gi 1756894684 334 YQRRRMP 340
Cdd:PRK06185  335 VQRRREF 341
PRK08244 PRK08244
monooxygenase;
155-369 3.25e-10

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 61.68  E-value: 3.25e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 155 TLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPPGDSTWQHFTPNGPHAFLPLFDNRASLVWYD--RPa 232
Cdd:PRK08244  145 TLTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVLSLCTREGGVMIVPLSGGIYRVLIIDpeRP- 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 233 RVRQLQAMSMTQLGREIAAAFPARLGRVTPVACGAFPLVRRHALRYVLPGVALIGDAAHtIH-PLAGQGVNLGYRDVDAL 311
Cdd:PRK08244  224 QVPKDEPVTLEELKTSLIRICGTDFGLNDPVWMSRFGNATRQAERYRSGRIFLAGDAAH-IHfPAGGQGLNVGLQDAMNL 302

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1756894684 312 ---LKVVIDArnaaedWASGAVLKRYQRRRMPDN--LLMQSGMDLFHAGFTaklKPLRVLRNL 369
Cdd:PRK08244  303 gwkLAAAIKG------WAPDWLLDSYHAERHPVGtaLLRNTEVQTKLFDFT---RPGLALRSM 356
PRK06126 PRK06126
hypothetical protein; Provisional
 103-340 4.71e-09

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 58.08  E-value: 4.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 103 PELGYMVENSVLQRALWEALEAHPAVQLLCPATLTQMT-----------PVQNGYQLsltngdTLQARLVIGADGASSQV 171
Cdd:PRK06126  117 PELPHRIPQKYLEPILLEHAAAQPGVTLRYGHRLTDFEqdadgvtatveDLDGGESL------TIRADYLVGCDGARSAV 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 172 RKWAGI---GVNAWQYQQSCLLISVECEQP-PGDSTWQHFTPNGphaflplfDNRASLVWYD-----RPARVRQLQAMSM 242
Cdd:PRK06126  191 RRSLGIsyeGTSGLQRDLSIYIRAPGLAALvGHDPAWMYWLFNP--------DRRGVLVAIDgrdewLFHQLRGGEDEFT 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 243 TQlGREIAAAFPARLGRVTPVACGAFPLVRRHAL---RYVLPGVALIGDAAHTIHPLAGQGVNLGYRDVDAL---LKVVI 316
Cdd:PRK06126  263 ID-DVDARAFVRRGVGEDIDYEVLSVVPWTGRRLvadSYRRGRVFLAGDAAHLFTPTGGYGMNTGIGDAVNLawkLAAVL 341

                         250       260
                  ....*....|....*....|....
gi 1756894684 317 DArnaaedWASGAVLKRYQRRRMP 340
Cdd:PRK06126  342 NG------WAGPALLDSYEAERRP 359
PRK06847 PRK06847
hypothetical protein; Provisional
 63-340 1.80e-07

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 52.57  E-value: 1.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684  63 LRGLGVWQRVLEmRAHPYRRLETWEWNEARV-----EFSADElQLP-ELGYMveNSVLQRALWEALEAHPA-VQLLCpaT 135
Cdd:PRK06847   56 LRELGVLDECLE-AGFGFDGVDLFDPDGTLLaelptPRLAGD-DLPgGGGIM--RPALARILADAARAAGAdVRLGT--T 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 136 LTQMTPVQNGYQLSLTNGDTLQARLVIGADGASSQVRK----------WAGIGVnaWQYQQSCLLISVECEQPPGDSTWQ 205
Cdd:PRK06847  130 VTAIEQDDDGVTVTFSDGTTGRYDLVVGADGLYSKVRSlvfpdepepeYTGQGV--WRAVLPRPAEVDRSLMYLGPTTKA 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 206 HFTPNGP-HAFLPLFDNRASLVWYDRPARVRQLqamsmtqlgREIAAAFPARLGR-VTPVACGAFPLVRRHALRYVLPG- 282
Cdd:PRK06847  208 GVVPLSEdLMYLFVTEPRPDNPRIEPDTLAALL---------RELLAPFGGPVLQeLREQITDDAQVVYRPLETLLVPAp 278

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1756894684 283 -----VALIGDAAHTIHPLAGQGVNLGYRdvDALlkVVIDARNAAEDWAsgAVLKRYQRRRMP 340
Cdd:PRK06847  279 whrgrVVLIGDAAHATTPHLAQGAGMAIE--DAI--VLAEELARHDSLE--AALQAYYARRWE 335
SE pfam08491
Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which ...
 281-368 9.73e-05

Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.


Pssm-ID: 400679  Cd Length: 276  Bit Score: 43.86  E-value: 9.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 281 PGVALIGDAAHTIHPLAGQGVNLGYRDVDALLKVVIDARNAAEDWASGAVLKRYQRRRMPD----NLLMQSgmdlFHAGF 356
Cdd:pfam08491 130 KGLILLGDALNMRHPLTGGGMTVGLNDIVLLRKLLGPLRDLSDREKVSKVLKSFHWKRKPYdaviNTLSIA----LYSLF 205

                          90
                  ....*....|..
gi 1756894684 357 TAKLKPLRVLRN 368
Cdd:pfam08491 206 AADSDELKALRK 217
PRK06184 PRK06184
hypothetical protein; Provisional
 153-340 4.88e-04

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 42.28  E-value: 4.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 153 GDTLQARLVIGADGASSQVRKWAGIG-VNAWQYQQSCLLISVECEQPPGDStWQHFTP--NGPHAFLPLfdnraslvwyd 229
Cdd:PRK06184  152 EETVRARYLVGADGGRSFVRKALGIGfPGETLGIDRMLVADVSLTGLDRDA-WHQWPDgdMGMIALCPL----------- 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 230 RPARVRQLQAmsMTQLGREI---AAAFPARLGRVT---------PVACGAFPLVRRHALRYVLPGVALIGDAAHtIHPLA 297
Cdd:PRK06184  220 PGTDLFQIQA--PLPPGGEPdlsADGLTALLAERTgrtdirlhsVTWASAFRMNARLADRYRVGRVFLAGDAAH-VHPPA 296

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1756894684 298 G-QGVNLGyrdvdallkvVIDARNAAedWASGAVLK--------RYQRRRMP 340
Cdd:PRK06184  297 GgQGLNTS----------VQDAYNLG--WKLAAVLAgapealldTYEEERRP 336
PRK07190 PRK07190
FAD-binding protein;
143-340 6.31e-04

FAD-binding protein;


Pssm-ID: 235955 [Multi-domain]  Cd Length: 487  Bit Score: 41.72  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 143 QNGYQLSLTNGDTLQARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEqppgdstwQHFtPNGPHafLPLFDNR 222
Cdd:PRK07190  139 QAGCLTTLSNGERIQSRYVIGADGSRSFVRNHFNVPFEIIRPQIIWAVIDGVID--------TDF-PKVPE--IIVFQAE 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 223 ASLV-WYDRPARV-RQLQAMSMTQLGREIA------AAFPARLGRVTPVACGAFPLVRRHALRYVLPG-VALIGDAAHtI 293
Cdd:PRK07190  208 TSDVaWIPREGEIdRFYVRMDTKDFTLEQAiakinhAMQPHRLGFKEIVWFSQFSVKESVAEHFFIQDrIFLAGDACH-I 286

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1756894684 294 HPL-AGQGVNLGYRDVDAL---LKVVIDARnaaedwASGAVLKRYQRRRMP 340
Cdd:PRK07190  287 HSVnGGQGLNTGLADAFNLiwkLNMVIHHG------ASPELLQSYEAERKP 331
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 158-337 1.64e-03

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 40.60  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 158 ARLVIGADGASSQVRKWAGIGVNAWQYQQSCLLISVECEQPPGDstwQH----FTPNGPHAFLPLFDNRAS-LVWYDRPA 232
Cdd:PTZ00367  208 APLVVMCDGGMSKFKSRYQHYTPASENHSHFVGLVLKNVRLPKE---QHgtvfLGKTGPILSYRLDDNELRvLVDYNKPT 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756894684 233 rVRQLQAMSmTQLGREIAAAFPARLG-------------RVTPVA--CGAFPLVRrhalryvlpGVALIGDAAHTIHPLA 297
Cdd:PTZ00367  285 -LPSLEEQS-EWLIEDVAPHLPENMResfiraskdtkriRSMPNAryPPAFPSIK---------GYVGIGDHANQRHPLT 353

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1756894684 298 GQGVNLGYRDVDALLKVVI----------DARNAAEDWASGAVLKRYQRR 337
Cdd:PTZ00367  354 GGGMTCCFSDCIRLAKSLTgikslrsidqNEMAEIEDAIQAAILSYARNR 403
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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