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Conserved domains on  [gi|1758723587|gb|KAB2504795|]
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ornithine carbamoyltransferase [Bacillus cereus]

Protein Classification

ornithine carbamoyltransferase( domain architecture ID 11479748)

ornithine carbamoyltransferase reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to L-ornithine (ORN) to produce L-citrulline, as part of the urea cycle and L-arginine biosynthesis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
7-330 0e+00

ornithine carbamoyltransferase; Validated


:

Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 658.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:PRK02102    4 NLKGRSFLKLLDFTPEEIEYLIDLSIELKAAKKAGIEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPNDS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGD 166
Cdd:PRK02102   84 QLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFGPLKGLKLAYVGD 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 167 GRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEEEKFA 242
Cdd:PRK02102  164 GRNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKEtgakITITEDPEEAVKGADVIYTDVWVSMGEEDEWE 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 243 ERVELLRPYQVNMKMIKETGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTIKA 322
Cdd:PRK02102  244 ERIKLLKPYQVNMDLMKATGNPDVIFMHCLPAFHDTETKVGKEIAEKYGLKGLEVTDEVFESKYSIVFDEAENRMHTIKA 323

                  ....*...
gi 1758723587 323 VMAATLGN 330
Cdd:PRK02102  324 VMVATLGD 331
 
Name Accession Description Interval E-value
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
7-330 0e+00

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 658.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:PRK02102    4 NLKGRSFLKLLDFTPEEIEYLIDLSIELKAAKKAGIEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPNDS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGD 166
Cdd:PRK02102   84 QLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFGPLKGLKLAYVGD 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 167 GRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEEEKFA 242
Cdd:PRK02102  164 GRNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKEtgakITITEDPEEAVKGADVIYTDVWVSMGEEDEWE 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 243 ERVELLRPYQVNMKMIKETGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTIKA 322
Cdd:PRK02102  244 ERIKLLKPYQVNMDLMKATGNPDVIFMHCLPAFHDTETKVGKEIAEKYGLKGLEVTDEVFESKYSIVFDEAENRMHTIKA 323

                  ....*...
gi 1758723587 323 VMAATLGN 330
Cdd:PRK02102  324 VMVATLGD 331
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
7-330 0e+00

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 527.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:COG0078     2 NLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGDS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGD 166
Cdd:COG0078    82 QLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYVGD 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 167 GrNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEEEKFA 242
Cdd:COG0078   162 G-NNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAEsggsITITHDPAEAVKGADVVYTDVWVSMGQEEEAE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 243 ERVELLRPYQVNMKMIKETGnENVIFLHCLPAFHdvetmygeevyekyglkEMEVTDEVFRSKHSKVFDQAENRMHTIKA 322
Cdd:COG0078   241 ERIKAFKPYQVNEELMALAK-PDAIFMHCLPAHR-----------------GEEVTDEVIDGPQSVVFDEAENRLHAQKA 302

                  ....*...
gi 1758723587 323 VMAATLGN 330
Cdd:COG0078   303 LLAWLLGG 310
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
11-329 2.75e-155

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 437.17  E-value: 2.75e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  11 RSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLGK 90
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  91 KESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGrNN 170
Cdd:TIGR00658  81 GESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDG-NN 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 171 VANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEEEKFAERVE 246
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKEnggsVELTHDPVEAVKGADVIYTDVWVSMGEEDKKEERLK 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 247 LLRPYQVNMKMIKETgNENVIFLHCLPAFHDvetmygeevyekyglkeMEVTDEVFRSKHSKVFDQAENRMHTIKAVMAA 326
Cdd:TIGR00658 240 LFRPYQVNEELMELA-KPEVIFMHCLPAHRG-----------------EEVTDEVIEGPHSIVFDQAENRLHAQKAVMVA 301

                  ...
gi 1758723587 327 TLG 329
Cdd:TIGR00658 302 LLG 304
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
12-151 8.56e-73

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 221.53  E-value: 8.56e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  12 SFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLGKK 91
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSSG 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  92 ESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIRE 151
Cdd:pfam02729  81 ESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
 
Name Accession Description Interval E-value
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
7-330 0e+00

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 658.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:PRK02102    4 NLKGRSFLKLLDFTPEEIEYLIDLSIELKAAKKAGIEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPNDS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGD 166
Cdd:PRK02102   84 QLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFGPLKGLKLAYVGD 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 167 GRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEEEKFA 242
Cdd:PRK02102  164 GRNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKEtgakITITEDPEEAVKGADVIYTDVWVSMGEEDEWE 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 243 ERVELLRPYQVNMKMIKETGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTIKA 322
Cdd:PRK02102  244 ERIKLLKPYQVNMDLMKATGNPDVIFMHCLPAFHDTETKVGKEIAEKYGLKGLEVTDEVFESKYSIVFDEAENRMHTIKA 323

                  ....*...
gi 1758723587 323 VMAATLGN 330
Cdd:PRK02102  324 VMVATLGD 331
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
7-330 0e+00

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 527.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:COG0078     2 NLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGDS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGD 166
Cdd:COG0078    82 QLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYVGD 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 167 GrNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEEEKFA 242
Cdd:COG0078   162 G-NNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAEsggsITITHDPAEAVKGADVVYTDVWVSMGQEEEAE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 243 ERVELLRPYQVNMKMIKETGnENVIFLHCLPAFHdvetmygeevyekyglkEMEVTDEVFRSKHSKVFDQAENRMHTIKA 322
Cdd:COG0078   241 ERIKAFKPYQVNEELMALAK-PDAIFMHCLPAHR-----------------GEEVTDEVIDGPQSVVFDEAENRLHAQKA 302

                  ....*...
gi 1758723587 323 VMAATLGN 330
Cdd:COG0078   303 LLAWLLGG 310
PRK04284 PRK04284
ornithine carbamoyltransferase; Provisional
7-330 1.98e-173

ornithine carbamoyltransferase; Provisional


Pssm-ID: 235269 [Multi-domain]  Cd Length: 332  Bit Score: 484.25  E-value: 1.98e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:PRK04284    3 NLRNRSFLTLLDFTPKEIEYLLDLSEDLKRAKYAGIEVQKLKGKNIALIFEKDSTRTRCAFEVAAYDQGAHVTYLGPTGS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGK-LKNVKLVYVG 165
Cdd:PRK04284   83 QMGKKESTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEHLKKpYKDIKFTYVG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 166 DGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVID----LAKKYNEQVMITSNVEEAVANADVIYTDVWVSMGE-EEK 240
Cdd:PRK04284  163 DGRNNVANALMQGAAIMGMDFHLVCPKELNPDDELLNkckeIAAETGGKITITDDIDEGVKGSDVIYTDVWVSMGEpDEV 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 241 FAERVELLRPYQVNMKMIKETGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI 320
Cdd:PRK04284  243 WEERIKLLKPYQVNKEMMKKTGNPNAIFEHCLPSFHDLDTKVGKEIFEKYGLKEMEVTDEVFESKASVVFDEAENRMHTI 322
                         330
                  ....*....|
gi 1758723587 321 KAVMAATLGN 330
Cdd:PRK04284  323 KAVMVATLGE 332
PRK03515 PRK03515
ornithine carbamoyltransferase subunit I; Provisional
11-330 3.77e-172

ornithine carbamoyltransferase subunit I; Provisional


Pssm-ID: 179587 [Multi-domain]  Cd Length: 336  Bit Score: 481.14  E-value: 3.77e-172
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  11 RSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLGK 90
Cdd:PRK03515    7 RHFLRLLDFTPAELNSLLQLAAKLKADKKNGKEEQKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGH 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  91 KESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHV-GK-LKNVKLVYVGDGR 168
Cdd:PRK03515   87 KESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpGKaFNEMTLAYAGDAR 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 169 NNVANSLLVGGAIVGMDVRICTPESLWPAQEVI----DLAKKYNEQVMITSNVEEAVANADVIYTDVWVSMGE-EEKFAE 243
Cdd:PRK03515  167 NNMGNSLLEAAALTGLDLRLVAPKACWPEAALVtecrALAQKNGGNITLTEDIAEGVKGADFIYTDVWVSMGEpKEVWAE 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 244 RVELLRPYQVNMKMIKETGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKE-MEVTDEVFRSKHSKVFDQAENRMHTIKA 322
Cdd:PRK03515  247 RIALLRPYQVNSKMMQLTGNPQVKFLHCLPAFHDDQTTLGKKMAEEYGLHGgMEVTDEVFESAHSIVFDQAENRLHTIKA 326

                  ....*...
gi 1758723587 323 VMAATLGN 330
Cdd:PRK03515  327 VMVATLSK 334
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
11-329 2.75e-155

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 437.17  E-value: 2.75e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  11 RSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLGK 90
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  91 KESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGrNN 170
Cdd:TIGR00658  81 GESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDG-NN 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 171 VANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEEEKFAERVE 246
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKEnggsVELTHDPVEAVKGADVIYTDVWVSMGEEDKKEERLK 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 247 LLRPYQVNMKMIKETgNENVIFLHCLPAFHDvetmygeevyekyglkeMEVTDEVFRSKHSKVFDQAENRMHTIKAVMAA 326
Cdd:TIGR00658 240 LFRPYQVNEELMELA-KPEVIFMHCLPAHRG-----------------EEVTDEVIEGPHSIVFDQAENRLHAQKAVMVA 301

                  ...
gi 1758723587 327 TLG 329
Cdd:TIGR00658 302 LLG 304
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
7-328 1.34e-153

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 432.59  E-value: 1.34e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:PRK00779    1 MLMGRHFLSLDDLSPEELEELLDLAAELKKKRKAGEPHPPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIFLSPRDT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGD 166
Cdd:PRK00779   81 QLGRGEPIEDTARVLSRYVDAIMIRTFEHETLEELAEYSTVPVINGLTDLSHPCQILADLLTIYEHRGSLKGLKVAWVGD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 167 GrNNVANSLLVGGAIVGMDVRICTPESLWPAQEVID-LAKKYNEQVMITSNVEEAVANADVIYTDVWVSMGEEEKFAERV 245
Cdd:PRK00779  161 G-NNVANSLLLAAALLGFDLRVATPKGYEPDPEIVEkIAKETGASIEVTHDPKEAVKGADVVYTDVWVSMGQEAEAEERL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 246 ELLRPYQVNMKMIKETgNENVIFLHCLPAfHdvetmYGEevyekyglkemEVTDEVFRSKHSKVFDQAENRMHTIKAVMA 325
Cdd:PRK00779  240 KAFAPYQVNEELMALA-KPDAIFMHCLPA-H-----RGE-----------EVTDEVIDGPQSVVWDEAENRLHAQKALLA 301

                  ...
gi 1758723587 326 ATL 328
Cdd:PRK00779  302 WLL 304
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
7-328 3.17e-137

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 392.43  E-value: 3.17e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDI 86
Cdd:PRK01713    4 NLKNRHLLSLVNHTEREIKYLLDLSRDLKRAKYAGTEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPNSS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  87 QLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGK-LKNVKLVYVG 165
Cdd:PRK01713   84 QIGHKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFNGLTDEFHPTQMLADVLTMIENCDKpLSEISYVYIG 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 166 DGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSMGEE-EK 240
Cdd:PRK01713  164 DARNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKEsgarITVTDDIDKAVKGVDFVHTDVWVSMGEPlET 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 241 FAERVELLRPYQVNMKMIKETGNENVIFLHCLPAFHDVETMYGEEVYEKYG--LKEMEVTDEVFRSKHSKVFDQAENRMH 318
Cdd:PRK01713  244 WGERIKLLMPYQVTPELMKRTGNPKVKFMHCLPAFHNSETKVGRQIAEKYPelANGIEVTEDVFESPMNIAFEQAENRMH 323
                         330
                  ....*....|
gi 1758723587 319 TIKAVMAATL 328
Cdd:PRK01713  324 TIKAVMVASL 333
PRK12562 PRK12562
ornithine carbamoyltransferase subunit F; Provisional
11-329 2.78e-134

ornithine carbamoyltransferase subunit F; Provisional


Pssm-ID: 105755  Cd Length: 334  Bit Score: 385.18  E-value: 2.78e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  11 RSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLGK 90
Cdd:PRK12562    7 KHFLKLLDFTPAELNSLLQLAAKLKADKKNGKEVARLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGH 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  91 KESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHV-GKLKN-VKLVYVGDGR 168
Cdd:PRK12562   87 KESIKDTARVLGRMYDGIQYRGHGQEVVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpGKAFNeMTLVYAGDAR 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 169 NNVANSLLVGGAIVGMDVRICTPESLWPAQEVI----DLAKKYNEQVMITSNVEEAVANADVIYTDVWVSMGE-EEKFAE 243
Cdd:PRK12562  167 NNMGNSMLEAAALTGLDLRLVAPQACWPEASLVaecsALAQKHGGKITLTEDIAAGVKGADFIYTDVWVSMGEpKEKWAE 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 244 RVELLRPYQVNMKMIKETGNENVIFLHCLPAFHDVETMYGEEVYEKYGLK-EMEVTDEVFRSKHSKVFDQAENRMHTIKA 322
Cdd:PRK12562  247 RIALLRGYQVNSKMMALTGNPQVKFLHCLPAFHDDQTTLGKKMAKEFGLHgGMEVTDEVFESPASIVFDQAENRMHTIKA 326

                  ....*..
gi 1758723587 323 VMAATLG 329
Cdd:PRK12562  327 VMVATLA 333
PLN02342 PLN02342
ornithine carbamoyltransferase
6-329 1.32e-104

ornithine carbamoyltransferase


Pssm-ID: 177976 [Multi-domain]  Cd Length: 348  Bit Score: 310.18  E-value: 1.32e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   6 PNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNG----IPhhyLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYL 81
Cdd:PLN02342   41 GKSKPKHFLHIDDFDKEEILGLLDRAKEVKALLKSGdrsfQP---FKGKSMAMIFTKPSMRTRVSFETGFFLLGGHALYL 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  82 GKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKL 161
Cdd:PLN02342  118 GPDDIQLGKREETRDIARVLSRYNDIIMARVFAHQDVLDLAEYSSVPVINGLTDYNHPCQIMADALTIIEHIGRLEGTKV 197
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 162 VYVGDGrNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYN-EQVMITSNVEEAVANADVIYTDVWVSMGEEEK 240
Cdd:PLN02342  198 VYVGDG-NNIVHSWLLLAAVLPFHFVCACPKGYEPDAKTVEKARAAGiSKIEITNDPAEAVKGADVVYTDVWASMGQKEE 276
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 241 FAERVELLRPYQVNMKMIKETGnENVIFLHCLPAFhdvetmygeevyekyglKEMEVTDEVFRSKHSKVFDQAENRMHTI 320
Cdd:PLN02342  277 AEKRKKAFQGFQVNEALMKLAG-PQAYFMHCLPAE-----------------RGVEVTDGVMEAPNSIVFPQAENRMHAQ 338

                  ....*....
gi 1758723587 321 KAVMAATLG 329
Cdd:PLN02342  339 NAIMLHQLG 347
PRK14805 PRK14805
ornithine carbamoyltransferase; Provisional
13-330 1.80e-95

ornithine carbamoyltransferase; Provisional


Pssm-ID: 237819 [Multi-domain]  Cd Length: 302  Bit Score: 285.04  E-value: 1.80e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  13 FLAEKDFTQEELLYFLDLAAELKEKkkngiPHHY---LEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLG 89
Cdd:PRK14805    4 LLSIKELTQQQLLDLLALAKTIKAN-----PAEYrqaLAGKSVVMLFEKPSLRTRVSFDIGINKLGGHCLYLDQQNGALG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  90 KKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGrN 169
Cdd:PRK14805   79 KRESVADFAANLSCWADAIVARVFSHSTIEQLAEHGSVPVINALCDLYHPCQALADFLTLAEQFGDVSKVKLAYVGDG-N 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 170 NVANSLLVGGAIVGMDVRICTPESLWPAQEVI----DLAKKYNEQVMITSNVeEAVANADVIYTDVWVSMGEEEKFAERV 245
Cdd:PRK14805  158 NVTHSLMYGAAILGATMTVICPPGHFPDGQIVaeaqELAAKSGGKLVLTSDI-EAIEGHDAIYTDTWISMGDDTPLAEIK 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 246 ELLRPYQVNMKMIKETGNENviFLHCLPAFhdvetmygeevyekyglKEMEVTDEVFRSKHSKVFDQAENRMHTIKAVMA 325
Cdd:PRK14805  237 AKFAPYQVNKALMEKAGATF--VMHCQPAH-----------------RGVEITSEVMDGEGSLILQQAENRMHAQNAVLV 297

                  ....*
gi 1758723587 326 ATLGN 330
Cdd:PRK14805  298 TLLSQ 302
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
12-151 8.56e-73

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 221.53  E-value: 8.56e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  12 SFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLGKK 91
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSSG 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  92 ESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIRE 151
Cdd:pfam02729  81 ESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
160-327 8.70e-67

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 206.69  E-value: 8.70e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 160 KLVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQ----VMITSNVEEAVANADVIYTDVWVSM 235
Cdd:pfam00185   1 KIAYVGDGHNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKsggsIEITDDPAEAVKGADVVYTDVWQSM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 236 GEEEKFAERVELLRPYQVNMKMIKETGNeNVIFLHCLPAFHDvetmygeevyekyglkeMEVTDEVFRSKHSKVFDQAEN 315
Cdd:pfam00185  81 GQEKEREERLKAFKPYQVNEELMKLAKK-DAIFMHCLPAHRG-----------------EEVTDDVFDGPRSVVFDQAEN 142
                         170
                  ....*....|..
gi 1758723587 316 RMHTIKAVMAAT 327
Cdd:pfam00185 143 RLHAQKALLALL 154
PyrB COG0540
Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; ...
7-332 2.71e-49

Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; Aspartate carbamoyltransferase, catalytic subunit is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440306 [Multi-domain]  Cd Length: 306  Bit Score: 166.77  E-value: 2.71e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGA-----NPEY- 80
Cdd:COG0540     2 SFKMRHLLSIEDLSREEIEELLDTAEEFKEVLRPIKKVPLLRGKTVANLFFEPSTRTRLSFELAAKRLGAdvinfSASTs 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  81 -LGKGdiqlgkkESVEDTAKVLGRM-FDGIEFRgfnH---ETVESLAQNSGVPVWNGlTDMW--HPTQTLADLLTIREHV 153
Cdd:COG0540    82 sVSKG-------ESLADTIRTLEAYgADAIVIR---HpqeGAARLLAEHVDVPVINA-GDGAheHPTQALLDLYTIREEF 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 154 GKLKNVKLVYVGD---GRnnVANSLLVGGAIVGMDVRICTPESLWPaqevidlakKYNEQ--VMITSNVEEAVANADVIY 228
Cdd:COG0540   151 GRLDGLKVAIVGDlkhSR--VARSNIKALSKLGAEVTLVAPPTLLP---------EEIEElgVEVTTDLDEALPDADVVY 219
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 229 -TDV-WVSMGEEEKFAERvELLRPYQVNMKMIKETgNENVIFLHCLPAFHDVetmygeevyekyglkemEVTDEVFRSKH 306
Cdd:COG0540   220 mLRIqKERFTDGLFPSYR-EYKRSYGLTAERLALA-KPDAIVMHPGPRNRGV-----------------EIDSDVDDTPR 280
                         330       340       350
                  ....*....|....*....|....*....|
gi 1758723587 307 SKVFDQAEN----RMhtikAVMAATLGNME 332
Cdd:COG0540   281 SVIFEQVTNgvavRM----ALLYLLLGGEE 306
PRK14804 PRK14804
ornithine carbamoyltransferase; Provisional
3-330 7.91e-48

ornithine carbamoyltransferase; Provisional


Pssm-ID: 173265 [Multi-domain]  Cd Length: 311  Bit Score: 163.27  E-value: 7.91e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   3 MTRPNLKgrSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHhyLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLG 82
Cdd:PRK14804    1 MSESNVK--HLISWEDWSDSEILDLLDFAVHVKKNRVNYAGH--MSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLD 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  83 --KGDIQLgkkESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGK--LKN 158
Cdd:PRK14804   77 wmASNFQL---SDIDLEARYLSRNVSVIMARLKKHEDLLVMKNGSQVPVINGCDNMFHPCQSLADIMTIALDSPEipLNQ 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 159 VKLVYVGdGRNNVANSLLVGGAIVGMDVRICTP----ESLWPaqEVIDLAKKYNeQVMITSNVEEAVANADVIYTDVWVS 234
Cdd:PRK14804  154 KQLTYIG-VHNNVVNSLIGITAALGIHLTLVTPiaakENIHA--QTVERAKKKG-TLSWEMNLHKAVSHADYVYTDTWLD 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 235 M------GEEEKFAERVELLRPYQVNMKMIKETgneNVIFLHCLPafhdvetmygeeVYEKYglkemEVTDEVFRSKHSK 308
Cdd:PRK14804  230 MeffndpSYADKKKQRMELMMPYQINSSLMEKT---NAKVMHDMP------------IHAGY-----EITREVVLSDRSI 289
                         330       340
                  ....*....|....*....|..
gi 1758723587 309 VFDQAENRMHTIKAVMAATLGN 330
Cdd:PRK14804  290 IFQQAENRLDAQKAVILKLLEN 311
pyrB PRK00856
aspartate carbamoyltransferase catalytic subunit;
7-330 2.53e-42

aspartate carbamoyltransferase catalytic subunit;


Pssm-ID: 234849 [Multi-domain]  Cd Length: 305  Bit Score: 148.68  E-value: 2.53e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   7 NLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPH-HYLEDKNVALLFEKTSTRTRCAFTVACTDLGANpeYLG--- 82
Cdd:PRK00856    2 PLKMKHLLSIEDLSREEIELLLDTAEEFKEVLRREVKKvPLLRGKTVANLFFEPSTRTRLSFELAAKRLGAD--VINfsa 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  83 ------KGdiqlgkkESVEDTAKVLGRMF-DGIEFRgfnH---ETVESLAQNSGVPVWNGlTDMW--HPTQTLADLLTIR 150
Cdd:PRK00856   80 stssvsKG-------ETLADTIRTLSAMGaDAIVIR---HpqsGAARLLAESSDVPVINA-GDGShqHPTQALLDLLTIR 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 151 EHVGKLKNVKLVYVGD---GRnnVANSLLVGGAIVGMDVRICTPESLWPAQEvidlakkynEQVMITSNVEEAVANADVI 227
Cdd:PRK00856  149 EEFGRLEGLKVAIVGDikhSR--VARSNIQALTRLGAEVRLIAPPTLLPEGM---------PEYGVHTDLDEVIEDADVV 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 228 Y---------TDVWVSmgEEEKFAERvellrpYQVNMKMIKETgNENVIFLHCLPAFHDVetmygeevyekyglkemEVT 298
Cdd:PRK00856  218 MmlrvqkermDGGLLP--SYEEYKRS------YGLTAERLALA-KPDAIVMHPGPVNRGV-----------------EIA 271
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1758723587 299 DEVFRSKHSKVFDQAEN----RMhtikAVMAATLGN 330
Cdd:PRK00856  272 SDVADGPQSVIFEQVTNgvavRM----AVLELLLGG 303
PRK04523 PRK04523
N-acetylornithine carbamoyltransferase; Reviewed
11-329 9.62e-40

N-acetylornithine carbamoyltransferase; Reviewed


Pssm-ID: 235304 [Multi-domain]  Cd Length: 335  Bit Score: 142.58  E-value: 9.62e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  11 RSFLAEKDFTQEELLYFLDLAAELKEKKkngiPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYL--GKGDIQL 88
Cdd:PRK04523    4 KHFLNTQDWSRAELDALLTQAAAFKRNK----LGSALKGKSIALVFFNPSLRTRTSFELGAFQLGGHAVVLqpGKDAWPI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  89 ----------GKKESVEDTAKVLGRMFDGIEFRGFNHET----------VESLAQNSGVPVWNgLTDMWHPTQTLADLLT 148
Cdd:PRK04523   80 efelgavmdgETEEHIREVARVLSRYVDLIGVRAFPKFVdwskdrqdqvLNSFAKYSTVPVIN-METITHPCQELAHALA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 149 IREHVGKL---KNVKLVYVGDGR---NNVANSLLVGGAIVGMDVRICTPESLWPAQE-VIDLAKKYNEQ----VMITSNV 217
Cdd:PRK04523  159 LQEHFGTTlrgKKYVLTWTYHPKplnTAVANSALLIATRLGMDVTLLCPTPDYILDErYMDWAEQNAAEsggsLTVSHDI 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 218 EEAVANADVIYTDVWVSM---GEEEKFAERVELLRPYQVNMKMIKETgnENVIFLHCLPAFHDVEtmygeevyekyglke 294
Cdd:PRK04523  239 DSAYAGADVVYAKSWGALpffGNWEPEKPIRDQYQHFIVDERKMALT--NNGVFSHCLPLRRNVK--------------- 301
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1758723587 295 meVTDEVFRSKHSKVFDQAENRMHTIKAVMAATLG 329
Cdd:PRK04523  302 --VTDAVMDSPNCIAIDEAENRLHVQKAIMAALAS 334
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
11-290 1.46e-25

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 105.59  E-value: 1.46e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  11 RSFLAEKDF------TQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKG 84
Cdd:PRK07200   15 TSHMHEKDFlltwekTPDELKAVLDVADALRALREENISTKVFNSGLGISVFRDNSTRTRFSYASACNLLGLEVQDLDEG 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  85 DIQLGKKESVEDTAKVLGRMFDGIEFR---------GFNHETVESLAQ--NSGV----PVWNGL-TDMWHPTQTLADLLT 148
Cdd:PRK07200   95 KSQIAHGETVRETANMISFMADVIGIRddmyigkgnAYMREVGAAVDDgyKQGVlpqrPTLVNLqCDIDHPTQSMADLLH 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 149 IREHVGKLKNVKlvyvgdGRNnVANS----------LLVGGAIV------GMDVRICTPESLWPAQEVIDLAKKYNEQ-- 210
Cdd:PRK07200  175 LIEHFGGLENLK------GKK-IAMTwayspsygkpLSVPQGIIglmtrfGMDVTLAHPEGYDLMPEVVEVAKKNAKAsg 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 211 --VMITSNVEEAVANADVIYTDVWVSMGEEEKfaeRVELLRP----------------------YQVNMKMIKETGNENV 266
Cdd:PRK07200  248 gsFRQVNSMEEAFKDADIVYPKSWAPYKVMEE---RTELYRAgdhegikalekellaqnaqhkdWHCTEEMMKLTKDGKA 324
                         330       340
                  ....*....|....*....|....*...
gi 1758723587 267 IFLHCLPA-FHDVETMYGE---EVYEKY 290
Cdd:PRK07200  325 LYMHCLPAdISGVSCKEGEvteSVFDRY 352
PLN02527 PLN02527
aspartate carbamoyltransferase
12-329 1.21e-20

aspartate carbamoyltransferase


Pssm-ID: 178142 [Multi-domain]  Cd Length: 306  Bit Score: 90.19  E-value: 1.21e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  12 SFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGAnpEYL---GKGDIQL 88
Cdd:PLN02527    2 DVIEAQQFDREMLELLFEVAREMEKVERGSPGSQMLKGYLMATLFYEPSTRTRLSFESAMKRLGG--EVLtteNAGEFSS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  89 GKK-ESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWN-GLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGD 166
Cdd:PLN02527   80 AAKgETLEDTIRTVEGYSDIIVLRHFESGAARRAAATAEIPVINaGDGPGQHPTQALLDVYTIQREIGRLDGIKVGLVGD 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 167 GRN-NVANSLLVGGAIV-GMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVANADVIYtdvwVSMGEEEKFAER 244
Cdd:PLN02527  160 LANgRTVRSLAYLLAKYeDVKIYFVAPDVVKMKDDIKDYLTSKGVEWEESSDLMEVASKCDVLY----QTRIQRERFGER 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 245 VELLRP----YQVNMKMIKETGNENVIfLHCLPAFHdvetmygeevyekyglkemEVTDEVFRSKHSKVFDQAENRMHTI 320
Cdd:PLN02527  236 IDLYEAargkYIVDKKVMDVLPKHAVV-MHPLPRLD-------------------EITTDVDSDPRAAYFRQAKNGLFIR 295

                  ....*....
gi 1758723587 321 KAVMAATLG 329
Cdd:PLN02527  296 MALLKLLLG 304
PRK08192 PRK08192
aspartate carbamoyltransferase; Provisional
55-273 8.28e-20

aspartate carbamoyltransferase; Provisional


Pssm-ID: 169269 [Multi-domain]  Cd Length: 338  Bit Score: 88.63  E-value: 8.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  55 LFEKTSTRTRCAFTVACTDLGAN-PEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGl 133
Cdd:PRK08192   50 LFFEPSTRTRVSFGCAFNLLGGHvRETTGMASSSLSKGESLYDTARVLSTYSDVIAMRHPDAGSVKEFAEGSRVPVING- 128
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 134 TD--MWHPTQTLADLLTIR---EHVGK-LKNVKLVYVGD---GRNNVANSLLVGgaiVGMDVRIC--TPESLWPAQEVID 202
Cdd:PRK08192  129 GDgsNEHPTQALLDLFTIQkelAHAGRgIDGMHIAMVGDlkfGRTVHSLSRLLC---MYKNVSFTlvSPKELAMPDYVIS 205
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1758723587 203 LAKKYNEQVMITSNVEEAVANADVIY-TDVwvsmgEEEKFA--ERVELLR-PYQVNMKMIKETGNENVIFLHCLP 273
Cdd:PRK08192  206 DIENAGHKITITDQLEGNLDKADILYlTRI-----QEERFPsqEEANKYRgKFRLNQSIYTQHCKSNTVIMHPLP 275
pyrB PRK13814
aspartate carbamoyltransferase;
26-229 3.37e-16

aspartate carbamoyltransferase;


Pssm-ID: 139876 [Multi-domain]  Cd Length: 310  Bit Score: 77.84  E-value: 3.37e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  26 YFLDLAAElkekkKNGIpHHYLEDKNVALLFEKTSTRTRCAFTVACTDLGA---NPEYLGKGdiqLGKKESVEDTAKVLG 102
Cdd:PRK13814   28 YFLTQGME-----KNSV-FETLKGHVVANLFFEPSTRTRNSFEIAAKRLGAmvlNPNLKISA---ISKGETLFDTIKTLE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 103 RMfdGIEF---RGFNHETVESLAQ--NSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGRNN-VANSLL 176
Cdd:PRK13814   99 AM--GVYFfivRHSENETPEQIAKqlSSGVVINAGDGNHQHPSQALIDLMTIKQHKPHWNKLCVTIIGDIRHSrVANSLM 176
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1758723587 177 VGGAIVGM-DVRICTPESLWPAQEVIDLAKKYNEqvmitsnVEEAVANADVIYT 229
Cdd:PRK13814  177 DGLVTMGVpEIRLVGPSSLLPDKVGNDSIKKFTE-------LKPSLLNSDVIVT 223
PRK11891 PRK11891
aspartate carbamoyltransferase; Provisional
22-273 1.65e-15

aspartate carbamoyltransferase; Provisional


Pssm-ID: 183362 [Multi-domain]  Cd Length: 429  Bit Score: 76.83  E-value: 1.65e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  22 EELLYFLDLAAELKEKKKNGiphHYLEDKNVALLFEKTSTRTRCAFTVACTDLGANP-EYLGKGDIQLGKKESVEDTAKV 100
Cdd:PRK11891  102 EALFRVADVMQPIARRQKIS---RVLEGAVLGNLFFEASTRTRVSFGAAFCRLGGSVcDTTGFTFSSMAKGESIYDTSRV 178
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 101 LGRMFDGIEFRGFNHETVESLAQNSGVPVWN-GLTDMWHPTQTLADLLTI-RE--HVGKL-KNVKLVYVGD---GRnnVA 172
Cdd:PRK11891  179 MSGYVDALVIRHPEQGSVAEFARATNLPVINgGDGPGEHPSQALLDLYTIqREfsRLGKIvDGAHIALVGDlkyGR--TV 256
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 173 NSLLVGGAIV-GMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVANADVIY-TDVwvsmgEEEKFA-ERVELLR 249
Cdd:PRK11891  257 HSLVKLLALYrGLKFTLVSPPTLEMPAYIVEQISRNGHVIEQTDDLAAGLRGADVVYaTRI-----QKERFAdESFEGYT 331
                         250       260
                  ....*....|....*....|....*
gi 1758723587 250 P-YQVNMKMIKETGNENVIFLHCLP 273
Cdd:PRK11891  332 PdFQINQALVDAVCKPDTLIMHPLP 356
pyrB PRK13376
bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase ...
3-273 1.61e-07

bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit; Provisional


Pssm-ID: 237369 [Multi-domain]  Cd Length: 525  Bit Score: 52.45  E-value: 1.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587   3 MTRpNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNG--IPHHYLEDKNVAL--LFEKTSTRTRCAFTVACT-DLGAN 77
Cdd:PRK13376    1 MKR-DFLGRTLAVIEDLSVEEQLFLYEKTRELKQRWYEGedVSEFRIKKRDVGIyiVFVEPSTRTKESFINAAKfHKNVK 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587  78 PEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEF------RG---FNHETVESLAQNSGVPVWN----GLTDMWHPTQTLA 144
Cdd:PRK13376   80 VNIFDSEHSSFNKQESYTDTFNMLTGYSDYSIFivrtrlEGvcrLLEEKVSEFASRNGIEVPAfinaGDGKHEHPTQELL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723587 145 DLLTIREHVG-KLKNVKLVYVGD---GR--NNVANSLLVGGAIvgmDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVE 218
Cdd:PRK13376  160 DEFTFLEQNNfDNSFIHIALVGDllhGRtvHSKVNGLKIFKNV---KVDLIAPEELAMPEHYVEKMKKNGFEVRIFSSIE 236
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1758723587 219 EAVANADViyTDVWV-------SMGEEekFAERVELLRPYQVNMKMIKETGNENVIFLHCLP 273
Cdd:PRK13376  237 EYLSQKDV--AKIWYftrlqleRMGED--ILEKEHILRKAVTFRKEFLDKLPEGVKFYHPLP 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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