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Conserved domains on  [gi|1758723733|gb|KAB2504925.1|]
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phage gp6-like head-tail connector protein [Bacillus cereus]

Protein Classification

head-tail connector protein( domain architecture ID 10169104)

phage gp6-like head-tail connector protein is critical in the assembly of the connector, a specialized phage structure that serves as an interface for head and tail attachment, as well as a point at which DNA exits the head during infection by the bacteriophage

Gene Ontology:  GO:0016032
PubMed:  19895817

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
gp6 cd08054
Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; The bacteriophage ...
 4-84 8.16e-23

Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; The bacteriophage HK97 gp6 protein is critical in the assembly of the connector, a specialized structure that serves as an interface for head and tail attachment, as well as a point at which DNA exits the head during infection by the bacteriophage. It forms a dodecameric ring structure that comprises the middle ring of the connector, located between the portal protein (attached to the head) and the gp7 ring (attached to the tail). It is a component of the mature phage and the absence of HK97 gp6 results in defective head-tail joining and the absence of mature phage particles. Although the crystal structure of HK97 gp6 shows an unexpected 13-mer ring, the biological form present in the mature phage is believed to be a dodecamer.


:

Pssm-ID: 153446  Cd Length: 91  Bit Score: 83.90  E-value: 8.16e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723733  4 TLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSKNVDLKS-------ELAKLAARILIAHWHENREAVG--KAEQLA 74
Cdd:cd08054    1 TLEEAKAHLRIDHDDDDALIELLIDAAEEYIENYTGRDLDEQTadaeevpALIKLAVLLLVAHLYENREAVTdvTASELP 80

                         90
                 ....*....|
gi 1758723733 75 FSLQSILVQL 84
Cdd:cd08054   81 FGVESLLAPY 90
 
Name Accession Description Interval E-value
gp6 cd08054
Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; The bacteriophage ...
 4-84 8.16e-23

Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; The bacteriophage HK97 gp6 protein is critical in the assembly of the connector, a specialized structure that serves as an interface for head and tail attachment, as well as a point at which DNA exits the head during infection by the bacteriophage. It forms a dodecameric ring structure that comprises the middle ring of the connector, located between the portal protein (attached to the head) and the gp7 ring (attached to the tail). It is a component of the mature phage and the absence of HK97 gp6 results in defective head-tail joining and the absence of mature phage particles. Although the crystal structure of HK97 gp6 shows an unexpected 13-mer ring, the biological form present in the mature phage is believed to be a dodecamer.


Pssm-ID: 153446  Cd Length: 91  Bit Score: 83.90  E-value: 8.16e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723733  4 TLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSKNVDLKS-------ELAKLAARILIAHWHENREAVG--KAEQLA 74
Cdd:cd08054    1 TLEEAKAHLRIDHDDDDALIELLIDAAEEYIENYTGRDLDEQTadaeevpALIKLAVLLLVAHLYENREAVTdvTASELP 80

                         90
                 ....*....|
gi 1758723733 75 FSLQSILVQL 84
Cdd:cd08054   81 FGVESLLAPY 90
put_DNA_pack TIGR01560
uncharacterized phage protein (possible DNA packaging); This model describes a small (~ 100 ...
 4-89 3.48e-13

uncharacterized phage protein (possible DNA packaging); This model describes a small (~ 100 amino acids) protein found in phage and in putative prophage regions of a number of bacterial genomes. Members have been annotated in some cases as a possible DNA packaging protein, but the source of this annotation was not traced during construction of this model. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 130623  Cd Length: 91  Bit Score: 59.32  E-value: 3.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723733  4 TLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSKNVDL---KSELAKLAARILIAHWHENREAV--GKAEQLAFSLQ 78
Cdd:TIGR01560  1 TLDEVKLSLRIDHDDDDELIKLMIAAAQDYIQSAIGTGVKDsfdSKPLFKLACIKLVAHYYENRGLYadRALVNVPIMVN 80

                         90
                 ....*....|.
gi 1758723733 79 SILVQLQYCGG 89
Cdd:TIGR01560 81 ALIHQLRGRGD 91
Phage_connect_1 pfam05135
Phage gp6-like head-tail connector protein; This family of proteins contain head-tail ...
 4-68 1.89e-07

Phage gp6-like head-tail connector protein; This family of proteins contain head-tail connector proteins related to gp6 from bacteriophage HK97. A structure of this protein shows similarity to gp15 a well characterized connector component of bacteriophage SPP1.


Pssm-ID: 428326  Cd Length: 93  Bit Score: 44.70  E-value: 1.89e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723733  4 TLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSK-----NVDLKSELAKLAARILIAHWHENREAVG 68
Cdd:pfam05135  3 TLEDIKTLLGIDDDSDDALLNSYIDAAEEYIENYLGRslgdpDAISLPADLKYAVLELAVARYNNRGNEG 72
 
Name Accession Description Interval E-value
gp6 cd08054
Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; The bacteriophage ...
 4-84 8.16e-23

Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; The bacteriophage HK97 gp6 protein is critical in the assembly of the connector, a specialized structure that serves as an interface for head and tail attachment, as well as a point at which DNA exits the head during infection by the bacteriophage. It forms a dodecameric ring structure that comprises the middle ring of the connector, located between the portal protein (attached to the head) and the gp7 ring (attached to the tail). It is a component of the mature phage and the absence of HK97 gp6 results in defective head-tail joining and the absence of mature phage particles. Although the crystal structure of HK97 gp6 shows an unexpected 13-mer ring, the biological form present in the mature phage is believed to be a dodecamer.


Pssm-ID: 153446  Cd Length: 91  Bit Score: 83.90  E-value: 8.16e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723733  4 TLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSKNVDLKS-------ELAKLAARILIAHWHENREAVG--KAEQLA 74
Cdd:cd08054    1 TLEEAKAHLRIDHDDDDALIELLIDAAEEYIENYTGRDLDEQTadaeevpALIKLAVLLLVAHLYENREAVTdvTASELP 80

                         90
                 ....*....|
gi 1758723733 75 FSLQSILVQL 84
Cdd:cd08054   81 FGVESLLAPY 90
put_DNA_pack TIGR01560
uncharacterized phage protein (possible DNA packaging); This model describes a small (~ 100 ...
 4-89 3.48e-13

uncharacterized phage protein (possible DNA packaging); This model describes a small (~ 100 amino acids) protein found in phage and in putative prophage regions of a number of bacterial genomes. Members have been annotated in some cases as a possible DNA packaging protein, but the source of this annotation was not traced during construction of this model. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 130623  Cd Length: 91  Bit Score: 59.32  E-value: 3.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723733  4 TLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSKNVDL---KSELAKLAARILIAHWHENREAV--GKAEQLAFSLQ 78
Cdd:TIGR01560  1 TLDEVKLSLRIDHDDDDELIKLMIAAAQDYIQSAIGTGVKDsfdSKPLFKLACIKLVAHYYENRGLYadRALVNVPIMVN 80

                         90
                 ....*....|.
gi 1758723733 79 SILVQLQYCGG 89
Cdd:TIGR01560 81 ALIHQLRGRGD 91
Phage_connect_1 pfam05135
Phage gp6-like head-tail connector protein; This family of proteins contain head-tail ...
 4-68 1.89e-07

Phage gp6-like head-tail connector protein; This family of proteins contain head-tail connector proteins related to gp6 from bacteriophage HK97. A structure of this protein shows similarity to gp15 a well characterized connector component of bacteriophage SPP1.


Pssm-ID: 428326  Cd Length: 93  Bit Score: 44.70  E-value: 1.89e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1758723733  4 TLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSK-----NVDLKSELAKLAARILIAHWHENREAVG 68
Cdd:pfam05135  3 TLEDIKTLLGIDDDSDDALLNSYIDAAEEYIENYLGRslgdpDAISLPADLKYAVLELAVARYNNRGNEG 72
phage_chp_gp8 TIGR02215
phage conserved hypothetical protein, phiE125 gp8 family; This model describes a family of ...
 3-40 2.64e-04

phage conserved hypothetical protein, phiE125 gp8 family; This model describes a family of proteins found exclusively in phage or in prophage regions of bacterial genomes, including the phage-like Rhodobacter capsulatus gene transfer agent, which packages DNA. Members of this family show some similarity to members of pfam05135, a putative DNA packaging protein family. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 274035 [Multi-domain]  Cd Length: 188  Bit Score: 37.86  E-value: 2.64e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1758723733   3 LTLEEAKKYLRVDSDEEDELITSFVIAAEIYIKNATSK 40
Cdd:TIGR02215  14 LTVADFKAHLRLGTEVEDAVLASLLRAARAAIEARTGK 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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