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Conserved domains on  [gi|1759772878|gb|KAB2754823|]
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helix-turn-helix transcriptional regulator [Brucella anthropi]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 11454547)

helix-turn-helix (HTH) transcriptional regulator containing an AraC family DNA-binding HTH domain controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

CATH:  1.10.10.1310
Gene Ontology:  GO:0003700|GO:0043565|GO:0006355
PubMed:  9409145|8831795|15808743|2644244
SCOP:  4000332

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
233-314 1.20e-23

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 92.62  E-value: 1.20e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  233 DLGTVTARFGVTARQVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPS 311
Cdd:smart00342   3 TLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLL-RDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 1759772878  312 AMR 314
Cdd:smart00342  82 EYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
87-319 1.98e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


:

Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 91.77  E-value: 1.98e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  87 LLMVRSMEGPLRIRQSGETLNLLPGDVVFLSPDKAYEWWLPEGGRVDCGRLPVSYFPVSKQAVKNFLMRPIPKAYPPLKL 166
Cdd:COG2207    25 LLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 167 LITHGAYLLMRGAHAPGEAEMIAAHFRQVLPMVLEFLRDDHRKHRSGRNLSQIKAFIETgLSDATFDLGTVTARFGVTAR 246
Cdd:COG2207   105 LLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLL-LLLLLLTLEELARELGLSPR 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1759772878 247 QVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQSHA 319
Cdd:COG2207   184 TLSRLFKEEtGTSPKQYLRELRLERAKRLL-AETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRA 256
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
233-314 1.20e-23

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 92.62  E-value: 1.20e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  233 DLGTVTARFGVTARQVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPS 311
Cdd:smart00342   3 TLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLL-RDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 1759772878  312 AMR 314
Cdd:smart00342  82 EYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
239-316 8.93e-23

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 90.34  E-value: 8.93e-23
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1759772878 239 ARFGVTARQVQKLFQAE-NTTFSRYVLERRLDMARLRVSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQ 316
Cdd:pfam12833   3 AALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRRR 81
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
87-319 1.98e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 91.77  E-value: 1.98e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  87 LLMVRSMEGPLRIRQSGETLNLLPGDVVFLSPDKAYEWWLPEGGRVDCGRLPVSYFPVSKQAVKNFLMRPIPKAYPPLKL 166
Cdd:COG2207    25 LLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 167 LITHGAYLLMRGAHAPGEAEMIAAHFRQVLPMVLEFLRDDHRKHRSGRNLSQIKAFIETgLSDATFDLGTVTARFGVTAR 246
Cdd:COG2207   105 LLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLL-LLLLLLTLEELARELGLSPR 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1759772878 247 QVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQSHA 319
Cdd:COG2207   184 TLSRLFKEEtGTSPKQYLRELRLERAKRLL-AETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRA 256
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 175-319 1.29e-19

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 87.91  E-value: 1.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 175 LMRGAHAPGEAEMIAAHfrqvlpMVLEFLRD----------DHRKHRSGRnLSQIKAFIETGLsDATFDLGTVTARFGVT 244
Cdd:COG4977   168 LVERDHGAELANAVARR------LVVDPRRPggqaqfspllVPLGHRDPR-LARAQAWMEANL-EEPLSVDELARRAGMS 239

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1759772878 245 ARQVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQSHA 319
Cdd:COG4977   240 PRTLERRFRAAtGTTPARYLQRLRLERARRLL-ETTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAYRRRFRA 314
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 90-317 3.87e-15

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 74.68  E-value: 3.87e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  90 VRSMEGPLRIRQSGETLNLLPGDVVFLSPDKAYEWwLPEG-----------GRVDcgrlpvSYFPVSKQAVKNFLMRPIP 158
Cdd:PRK09685   75 VFQLSGHAIIEQDDRQVQLAAGDITLIDASRPCSI-YPQGlseqislllprELVE------QYFPGQKPACAGRLSASLP 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 159 KAYppLKLLITHGaylLMRGAHAPG-EAEMIAAHFRQVLPMVLEFLrdDHRKHRSGRNLSQIKAFIETGLSDATFDLGTV 237
Cdd:PRK09685  148 MVQ--LSHRLLQQ---SMNGPALSEtESEALLEALIALLRPALHQR--ESVQPRRERQFQKVVALIDQSIQEEILRPEWI 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 238 TARFGVTARQVQKLFQAENTTFSRYVLERRLDM--ARLRvSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRD 315
Cdd:PRK09685  221 AGELGISVRSLYRLFAEQGLVVAQYIRNRRLDRcaDDLR-PAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRR 299


                  ..
gi 1759772878 316 QS 317
Cdd:PRK09685  300 KF 301
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
222-316 3.08e-09

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 53.78  E-value: 3.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 222 FIETGLsDATFDLGTVTARFGVTARQVQKLFQA-ENTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNR 300
Cdd:PRK10219   13 WIDEHI-DQPLNIDVVAKKSGYSKWYLQRMFRTvTHQTLGDYIRQRRLLLAAVEL-RTTERPIFDIAMDLGYVSQQTFSR 90

                          90
                  ....*....|....*.
gi 1759772878 301 VFRQHFGMTPSAMRDQ 316
Cdd:PRK10219   91 VFRRQFDRTPSDYRHR 106
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
233-314 1.20e-23

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 92.62  E-value: 1.20e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  233 DLGTVTARFGVTARQVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPS 311
Cdd:smart00342   3 TLEDLAEALGVSPRHLQRLFKKEtGTTPKQYLRDRRLERARRLL-RDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 1759772878  312 AMR 314
Cdd:smart00342  82 EYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
239-316 8.93e-23

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 90.34  E-value: 8.93e-23
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1759772878 239 ARFGVTARQVQKLFQAE-NTTFSRYVLERRLDMARLRVSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQ 316
Cdd:pfam12833   3 AALGMSPRTLSRLFKRElGLSPKEYLRRLRLERARRLLLEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRRR 81
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
87-319 1.98e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 91.77  E-value: 1.98e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  87 LLMVRSMEGPLRIRQSGETLNLLPGDVVFLSPDKAYEWWLPEGGRVDCGRLPVSYFPVSKQAVKNFLMRPIPKAYPPLKL 166
Cdd:COG2207    25 LLLILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 167 LITHGAYLLMRGAHAPGEAEMIAAHFRQVLPMVLEFLRDDHRKHRSGRNLSQIKAFIETgLSDATFDLGTVTARFGVTAR 246
Cdd:COG2207   105 LLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLL-LLLLLLTLEELARELGLSPR 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1759772878 247 QVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQSHA 319
Cdd:COG2207   184 TLSRLFKEEtGTSPKQYLRELRLERAKRLL-AETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRA 256
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 175-319 1.29e-19

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 87.91  E-value: 1.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 175 LMRGAHAPGEAEMIAAHfrqvlpMVLEFLRD----------DHRKHRSGRnLSQIKAFIETGLsDATFDLGTVTARFGVT 244
Cdd:COG4977   168 LVERDHGAELANAVARR------LVVDPRRPggqaqfspllVPLGHRDPR-LARAQAWMEANL-EEPLSVDELARRAGMS 239

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1759772878 245 ARQVQKLFQAE-NTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQSHA 319
Cdd:COG4977   240 PRTLERRFRAAtGTTPARYLQRLRLERARRLL-ETTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAYRRRFRA 314
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 218-316 1.04e-16

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 80.10  E-value: 1.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 218 QIKAFIETGlSDATFDLGTVTARFGVTARQVQKLFQAE-NTTFSRYVLERRLDMARLRVsrQNNRSISSIAYEVGFGDLS 296
Cdd:COG2169    88 RACRLIEAG-AEDRPSLEDLAARLGLSPRHLRRLFKAHtGVTPKAYARARRLLRARQLL--QTGLSVTDAAYAAGFGSLS 164

                          90       100
                  ....*....|....*....|
gi 1759772878 297 YFNRVFRQHFGMTPSAMRDQ 316
Cdd:COG2169   165 RFYEAFKKLLGMTPSAYRRG 184
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 90-317 3.87e-15

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 74.68  E-value: 3.87e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878  90 VRSMEGPLRIRQSGETLNLLPGDVVFLSPDKAYEWwLPEG-----------GRVDcgrlpvSYFPVSKQAVKNFLMRPIP 158
Cdd:PRK09685   75 VFQLSGHAIIEQDDRQVQLAAGDITLIDASRPCSI-YPQGlseqislllprELVE------QYFPGQKPACAGRLSASLP 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 159 KAYppLKLLITHGaylLMRGAHAPG-EAEMIAAHFRQVLPMVLEFLrdDHRKHRSGRNLSQIKAFIETGLSDATFDLGTV 237
Cdd:PRK09685  148 MVQ--LSHRLLQQ---SMNGPALSEtESEALLEALIALLRPALHQR--ESVQPRRERQFQKVVALIDQSIQEEILRPEWI 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 238 TARFGVTARQVQKLFQAENTTFSRYVLERRLDM--ARLRvSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRD 315
Cdd:PRK09685  221 AGELGISVRSLYRLFAEQGLVVAQYIRNRRLDRcaDDLR-PAADDEKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYRR 299


                  ..
gi 1759772878 316 QS 317
Cdd:PRK09685  300 KF 301
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
222-316 3.08e-09

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 53.78  E-value: 3.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 222 FIETGLsDATFDLGTVTARFGVTARQVQKLFQA-ENTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNR 300
Cdd:PRK10219   13 WIDEHI-DQPLNIDVVAKKSGYSKWYLQRMFRTvTHQTLGDYIRQRRLLLAAVEL-RTTERPIFDIAMDLGYVSQQTFSR 90

                          90
                  ....*....|....*.
gi 1759772878 301 VFRQHFGMTPSAMRDQ 316
Cdd:PRK10219   91 VFRRQFDRTPSDYRHR 106
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 273-314 2.33e-08

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 49.46  E-value: 2.33e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1759772878 273 LRVSRQNNRSISSIAYEVGFgDLSYFNRVFRQHFGMTPSAMR 314
Cdd:pfam00165   1 LRENLSTNLTIADIADELGF-SRSYFSRLFKKYTGVTPSQYR 41
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 248-317 2.73e-08

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 54.16  E-value: 2.73e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 248 VQKLFQAENTTFSRYVLERRLDMArLRVSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQS 317
Cdd:PRK09978  175 LKKKLREEETSYSQLLTECRMQRA-LQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTEYQERS 243
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
174-325 3.21e-08

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 53.91  E-value: 3.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 174 LLMRGAHAPGEAEMIAAHFRQVLPM-VLEFLRDDHRKHRSGRN---LSQIKAFIETGLSDATfDLGTVTARFGVTARQVQ 249
Cdd:PRK13503  127 LVAQMEQQEESNDLEAIASREILFMqLLVLLRKSSLQENGENSdarLNQLLAWLEDHFAEEV-NWEALADQFSLSLRTLH 205

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1759772878 250 K-LFQAENTTFSRYVLERRLDMARLRVsRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPsamRDQSHAMVSQIQ 325
Cdd:PRK13503  206 RqLKQQTGLTPQRYLNRLRLLKARHLL-RHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSP---RDIRQGRDGFLQ 278
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
196-316 8.36e-08

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 52.98  E-value: 8.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 196 LPMVLEFLRDDHRKHRS-----GRNLSQIKAFIETGLSdATFDLGTVTARFGVTARQVQKLF-QAENTTFSRYVLERRLD 269
Cdd:PRK13501  153 LQLAIVLKRHRYRAEQAhllpdGEQLDLIMSALQQSLG-AYFDMADFCHKNQLVERSLKQLFrQQTGMSISHYLRQIRLC 231

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1759772878 270 MARLRVSRQNNRsISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQ 316
Cdd:PRK13501  232 HAKCLLRGSEHR-ISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQR 277
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 248-311 1.72e-06

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 48.91  E-value: 1.72e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1759772878 248 VQKLFQAENTTFSRYVLERRLDMARlRVSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTPS 311
Cdd:PRK15186  214 LKRKLKQENTSFSEVYLNARMNKAT-KLLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTPS 276
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 243-318 5.29e-06

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 47.00  E-value: 5.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 243 VTARQVQKLFQAENTTFSRYVLERRLDMARLRVSRQNnrSISSIAYEVGFGDLSYFNRVFRQHFGMTPSAM----RDQSH 318
Cdd:PRK09940  162 ISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEG--SVNKIAEQCGYASTSYFIYAFRKHFGNSPKRVskeyRCQRH 239
ftrA PRK09393
transcriptional activator FtrA; Provisional
 210-316 8.34e-06

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 46.88  E-value: 8.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 210 HRSGRNLSQIKAFIETGLSdATFDLGTVTARFGVTARQVQKLFQ-AENTTFSRYVLERRLDMAR--LRVSRQnnrSISSI 286
Cdd:PRK09393  214 SRESDRLGPLIDWMRAHLA-EPHTVASLAARAAMSPRTFLRRFEaATGMTPAEWLLRERLARARdlLESSAL---SIDQI 289

                          90       100       110
                  ....*....|....*....|....*....|
gi 1759772878 287 AYEVGFGDLSYFNRVFRQHFGMTPSAMRDQ 316
Cdd:PRK09393  290 AERAGFGSEESLRHHFRRRAATSPAAYRKR 319
PRK15044 PRK15044
transcriptional regulator SirC; Provisional
 237-318 1.34e-05

transcriptional regulator SirC; Provisional


Pssm-ID: 185004 [Multi-domain]  Cd Length: 295  Bit Score: 46.18  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 237 VTARFGVTARQVQKLFQAENTTFSRYVLERRLDMArLRVSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGMTP-SAMRD 315
Cdd:PRK15044  214 VAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQA-IKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPlSFMRT 292


                  ...
gi 1759772878 316 QSH 318
Cdd:PRK15044  293 MNH 295
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 229-318 1.69e-05

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 45.76  E-value: 1.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 229 DATFDLGTVTARFGVTARQVQKLFQAENTTFSRYVLERRLDMARlRVSRQNNRSISSIAYEVGFGDLSYFNRVFRQHFGM 308
Cdd:PRK15185  220 SRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAA-KLLRIGNHNVNAVALKCGYDSTSYFIQCFKKYFKT 298

                          90
                  ....*....|.
gi 1759772878 309 TPSA-MRDQSH 318
Cdd:PRK15185  299 TPSTfIKMANH 309
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
274-322 2.09e-05

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 45.35  E-value: 2.09e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1759772878 274 RVSR-----QNNR-SISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQSHAMVS 322
Cdd:PRK10572  236 RISRaklllQTTRmPIATIGRNVGYDDQLYFSRVFKKCTGASPSEFRARCEEKNN 290
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
249-314 2.40e-03

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 39.31  E-value: 2.40e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1759772878 249 QKLFQAENTTFSRYVLERRLDMARLRVsrQNNRS-ISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMR 314
Cdd:PRK13500  241 QQFRQQTGMTINQYLRQVRVCHAQYLL--QHSRLlISDISTECGFEDSNYFSVVFTRETGMTPSQWR 305
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
249-317 2.84e-03

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 38.88  E-value: 2.84e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1759772878 249 QKLFQAENTTFSRYVLERRLDMARLRVsrQNNR-SISSIAYEVGFGDLSYFNRVFRQHFGMTPSAMRDQS 317
Cdd:PRK13502  211 QQFRAQTGMTINQYLRQVRICHAQYLL--QHSPlMISEISMQCGFEDSNYFSVVFTRETGMTPSQWRHLS 278
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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