NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1786821480|gb|KAF0193691|]
View 

MAG: SpoIID/LytB domain-containing protein [Bacillota bacterium]

Protein Classification

SH3 domain-containing protein( domain architecture ID 11459669)

Src Homology 3 (SH3) domain-containing protein plays versatile and diverse roles in the cell, including the regulation of enzymes, changing the subcellular localization of signaling pathway components, and mediating the formation of multiprotein complex assemblies, among others

CATH:  2.30.30.40
Gene Ontology:  GO:0005515|GO:0070064
PubMed:  28510178|11256992|1639195
SCOP:  4000369

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YgiM COG3103
Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family ...
 136-183 7.21e-11

Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family [General function prediction only];


:

Pssm-ID: 442337 [Multi-domain]  Cd Length: 119  Bit Score: 56.67  E-value: 7.21e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEKGKVWHKVKYQDSV-GYVSSEF 183
Cdd:COG3103    14 LNVRSGPGTSYRIVGTLPKGEKVTVLGRSGGWYKVRYSNGKtGWVSSRY 62
 
Name Accession Description Interval E-value
YgiM COG3103
Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family ...
 136-183 7.21e-11

Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family [General function prediction only];


Pssm-ID: 442337 [Multi-domain]  Cd Length: 119  Bit Score: 56.67  E-value: 7.21e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEKGKVWHKVKYQDSV-GYVSSEF 183
Cdd:COG3103    14 LNVRSGPGTSYRIVGTLPKGEKVTVLGRSGGWYKVRYSNGKtGWVSSRY 62
SH3_3 pfam08239
Bacterial SH3 domain;
136-183 4.19e-09

Bacterial SH3 domain;


Pssm-ID: 462405 [Multi-domain]  Cd Length: 54  Bit Score: 50.32  E-value: 4.19e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEK-GKVWHKVK-YQDSVGYVSSEF 183
Cdd:pfam08239   3 LNVRSGPSTSSEVVGTLPKGEKVEVLEEqGGGWYKVRtYDGYEGWVSSSY 52
SH3b smart00287
Bacterial SH3 domain homologues;
129-183 9.20e-06

Bacterial SH3 domain homologues;


Pssm-ID: 214600 [Multi-domain]  Cd Length: 63  Bit Score: 41.55  E-value: 9.20e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1786821480  129 GFINGKMVNIRTGAGTNFSIIVTLPMNTRLEVL-EKGKVWHKVKYQ-DSVGYVSSEF 183
Cdd:smart00287   4 AVVTGDGLNVRTGPGTSSPIIGTLKKGDKVKVLgVDGQDWAKITYGsGQRGYVPGYV 60
SH3_and_anchor TIGR04211
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ...
 136-183 4.06e-05

SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.


Pssm-ID: 275056 [Multi-domain]  Cd Length: 198  Bit Score: 42.30  E-value: 4.06e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEKGK-VWHKVKYQDSV-GYVSSEF 183
Cdd:TIGR04211   8 VYMRSGPGNQYRILGSLKSGTPVTVLERSEdGYSRVRTPKGReGWVLSRY 57
 
Name Accession Description Interval E-value
YgiM COG3103
Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family ...
 136-183 7.21e-11

Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family [General function prediction only];


Pssm-ID: 442337 [Multi-domain]  Cd Length: 119  Bit Score: 56.67  E-value: 7.21e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEKGKVWHKVKYQDSV-GYVSSEF 183
Cdd:COG3103    14 LNVRSGPGTSYRIVGTLPKGEKVTVLGRSGGWYKVRYSNGKtGWVSSRY 62
YraI COG4991
Uncharacterized conserved protein YraI [Function unknown];
131-183 4.77e-10

Uncharacterized conserved protein YraI [Function unknown];


Pssm-ID: 444015 [Multi-domain]  Cd Length: 92  Bit Score: 53.91  E-value: 4.77e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1786821480 131 INGKMVNIRTGAGTNFSIIVTLPMNTRLEVLEK--GKVWHKVKYQDSVGYVSSEF 183
Cdd:COG4991    26 VATDDLNLRSGPGTGYPVVGTLPAGATVTVLGCtsGGGWCKVSYGGQRGWVSARY 80
SH3_3 pfam08239
Bacterial SH3 domain;
136-183 4.19e-09

Bacterial SH3 domain;


Pssm-ID: 462405 [Multi-domain]  Cd Length: 54  Bit Score: 50.32  E-value: 4.19e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEK-GKVWHKVK-YQDSVGYVSSEF 183
Cdd:pfam08239   3 LNVRSGPSTSSEVVGTLPKGEKVEVLEEqGGGWYKVRtYDGYEGWVSSSY 52
SH3b smart00287
Bacterial SH3 domain homologues;
129-183 9.20e-06

Bacterial SH3 domain homologues;


Pssm-ID: 214600 [Multi-domain]  Cd Length: 63  Bit Score: 41.55  E-value: 9.20e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1786821480  129 GFINGKMVNIRTGAGTNFSIIVTLPMNTRLEVL-EKGKVWHKVKYQ-DSVGYVSSEF 183
Cdd:smart00287   4 AVVTGDGLNVRTGPGTSSPIIGTLKKGDKVKVLgVDGQDWAKITYGsGQRGYVPGYV 60
SH3_and_anchor TIGR04211
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ...
 136-183 4.06e-05

SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.


Pssm-ID: 275056 [Multi-domain]  Cd Length: 198  Bit Score: 42.30  E-value: 4.06e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEKGK-VWHKVKYQDSV-GYVSSEF 183
Cdd:TIGR04211   8 VYMRSGPGNQYRILGSLKSGTPVTVLERSEdGYSRVRTPKGReGWVLSRY 57
YgiM COG3103
Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family ...
 136-179 8.14e-05

Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family [General function prediction only];


Pssm-ID: 442337 [Multi-domain]  Cd Length: 119  Bit Score: 40.49  E-value: 8.14e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1786821480 136 VNIRTGAGTNFSIIVTLPMNTRLEVLEKGKVWHKVKYqDSVGYV 179
Cdd:COG3103    77 LNLRAGPSTSSEVLGLLPKGETVTVLKKSGGWFKVGY-RGTGWV 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH