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Conserved domains on  [gi|616721669|gb|KAF18361|]
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hypothetical protein W646_01649 [Staphylococcus aureus VET0423R]

Protein Classification

DUF72 domain-containing protein( domain architecture ID 10004534)

DUF72 domain-containing protein adopts a TIM beta/alpha barrel fold; similar to Bacillus subtilis UPF0759 protein YunF

CATH:  3.20.20.410
SCOP:  4003323

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YecE COG1801
Sugar isomerase-related protein YecE, UPF0759/DUF72 family [General function prediction only];
1-271 1.01e-85

Sugar isomerase-related protein YecE, UPF0759/DUF72 family [General function prediction only];


:

Pssm-ID: 441406  Cd Length: 241  Bit Score: 256.26  E-value: 1.01e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669   1 MINIGLTGWGDH---YSLYEDLERQTDKLKTYAGHFPVVELDATYYAIQPERNILKWIKETPDTFEFVVKIHQALTLHad 77
Cdd:COG1801    1 MIRIGTSGWSYPdwrGVFYPEGLPAKDELEYYARHFNTVEINSTFYALPSPETVARWAAQTPDGFRFSVKAPRFITHE-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  78 yKTFADTrQELFDQFKNMLEPLHtqKKLAMVLVQFPPWFDCNAQNIKYILYvrqQL-QSFPMCVEFRHQSWFSDAFkeqt 156
Cdd:COG1801   79 -RRLADA-EELLERFLESLEPLG--DKLGPLLFQLPPSFKFDPERLEAFLA---LLpRGLRHAVEVRHPSWFTPEV---- 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669 157 LSFLTEHQIIHAVVDEPqvkdgSVPLVNRITNEIAFVRYHGRNhygwtkkdmsdqewrdVRYLYDYNEQELIDLAQKAQI 236
Cdd:COG1801  148 LALLREHGVALVIADSP-----RVPPIAVTTADFVYVRLHGRN----------------ERYDYGYSPEELDEWAERIRA 206
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 616721669 237 LAQKAKKVYVIFNNNSGGHAANNAKTYQRLLNIEY 271
Cdd:COG1801  207 WAAEGRDVYVYFNNDAEGHAPANALALAELLGAAG 241
 
Name Accession Description Interval E-value
YecE COG1801
Sugar isomerase-related protein YecE, UPF0759/DUF72 family [General function prediction only];
1-271 1.01e-85

Sugar isomerase-related protein YecE, UPF0759/DUF72 family [General function prediction only];


Pssm-ID: 441406  Cd Length: 241  Bit Score: 256.26  E-value: 1.01e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669   1 MINIGLTGWGDH---YSLYEDLERQTDKLKTYAGHFPVVELDATYYAIQPERNILKWIKETPDTFEFVVKIHQALTLHad 77
Cdd:COG1801    1 MIRIGTSGWSYPdwrGVFYPEGLPAKDELEYYARHFNTVEINSTFYALPSPETVARWAAQTPDGFRFSVKAPRFITHE-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  78 yKTFADTrQELFDQFKNMLEPLHtqKKLAMVLVQFPPWFDCNAQNIKYILYvrqQL-QSFPMCVEFRHQSWFSDAFkeqt 156
Cdd:COG1801   79 -RRLADA-EELLERFLESLEPLG--DKLGPLLFQLPPSFKFDPERLEAFLA---LLpRGLRHAVEVRHPSWFTPEV---- 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669 157 LSFLTEHQIIHAVVDEPqvkdgSVPLVNRITNEIAFVRYHGRNhygwtkkdmsdqewrdVRYLYDYNEQELIDLAQKAQI 236
Cdd:COG1801  148 LALLREHGVALVIADSP-----RVPPIAVTTADFVYVRLHGRN----------------ERYDYGYSPEELDEWAERIRA 206
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 616721669 237 LAQKAKKVYVIFNNNSGGHAANNAKTYQRLLNIEY 271
Cdd:COG1801  207 WAAEGRDVYVYFNNDAEGHAPANALALAELLGAAG 241
DUF72 pfam01904
Protein of unknown function DUF72; The function of this family is unknown.
22-266 1.15e-74

Protein of unknown function DUF72; The function of this family is unknown.


Pssm-ID: 426503  Cd Length: 220  Bit Score: 227.46  E-value: 1.15e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669   22 QTDKLKTYAGHFPVVELDATYYAIQPERNILKWIKETPDTFEFVVKIHQALTLHADYKTFAdtRQELFDQFKNMLEPLHt 101
Cdd:pfam01904   1 QRERLEYYARHFNTVEINSTFYRLPSPETVARWAEQTPDGFRFSVKAPRFITHRKRLRDLD--AEEALARFLEALEPLG- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  102 qKKLAMVLVQFPPWFDCNAQNIKYILYVRQQL-QSFPMCVEFRHQSWFSDAFkeqtLSFLTEHQIIHAVVDEPqvKDGSV 180
Cdd:pfam01904  78 -GKLGPLLFQLPPSFKFDPENLERLEAFLALLpRGLRLAVEFRHPSWFTPEV----LELLREHGVALVVADEP--SPGRL 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  181 PLVNRITNEIAFVRYHGRNHYGWtkkdmsdqewrdvrylYDYNEQELIDLAQKAQILAQKAKKVYVIFNNNSGGHAANNA 260
Cdd:pfam01904 151 PPEDVTTADFAYVRLHGRNELYW----------------YRYSDEELDEWAERIRAWAAEGRDVYVFFNNDAEGHAPLNA 214

                  ....*.
gi 616721669  261 KTYQRL 266
Cdd:pfam01904 215 RRLAEL 220
PRK10302 PRK10302
hypothetical protein; Provisional
1-157 9.00e-06

hypothetical protein; Provisional


Pssm-ID: 182366  Cd Length: 272  Bit Score: 46.17  E-value: 9.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669   1 MINIGLTGWgdHYSLYEDLERQTdkLKTYAGHFPVVELDATYYAIQPERNILKWIKETPDTFEFVVKI-----HQALTLH 75
Cdd:PRK10302   1 MIYIGLPQW--QHPKWVRLGITS--LEDYARHFNCVEGNTTLYALPKPEIVLRWRDMTTDDFRFCFKFpatisHQAALRH 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  76 ADyktfadtrqELFDQFKNMLEPLHTqkKLAMVLVQFPPWF---DCNAqnikyiLYvrQQLQSFP----MCVEFRHQSWF 148
Cdd:PRK10302  77 CD---------DLVQEFFTRLAPLAD--RIGQYWLQLPAAFgprELPA------LW--QFLDALPagftYGVEVRHPEFF 137

                 ....*....
gi 616721669 149 SDAFKEQTL 157
Cdd:PRK10302 138 AKGEAEQAL 146
 
Name Accession Description Interval E-value
YecE COG1801
Sugar isomerase-related protein YecE, UPF0759/DUF72 family [General function prediction only];
1-271 1.01e-85

Sugar isomerase-related protein YecE, UPF0759/DUF72 family [General function prediction only];


Pssm-ID: 441406  Cd Length: 241  Bit Score: 256.26  E-value: 1.01e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669   1 MINIGLTGWGDH---YSLYEDLERQTDKLKTYAGHFPVVELDATYYAIQPERNILKWIKETPDTFEFVVKIHQALTLHad 77
Cdd:COG1801    1 MIRIGTSGWSYPdwrGVFYPEGLPAKDELEYYARHFNTVEINSTFYALPSPETVARWAAQTPDGFRFSVKAPRFITHE-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  78 yKTFADTrQELFDQFKNMLEPLHtqKKLAMVLVQFPPWFDCNAQNIKYILYvrqQL-QSFPMCVEFRHQSWFSDAFkeqt 156
Cdd:COG1801   79 -RRLADA-EELLERFLESLEPLG--DKLGPLLFQLPPSFKFDPERLEAFLA---LLpRGLRHAVEVRHPSWFTPEV---- 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669 157 LSFLTEHQIIHAVVDEPqvkdgSVPLVNRITNEIAFVRYHGRNhygwtkkdmsdqewrdVRYLYDYNEQELIDLAQKAQI 236
Cdd:COG1801  148 LALLREHGVALVIADSP-----RVPPIAVTTADFVYVRLHGRN----------------ERYDYGYSPEELDEWAERIRA 206
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 616721669 237 LAQKAKKVYVIFNNNSGGHAANNAKTYQRLLNIEY 271
Cdd:COG1801  207 WAAEGRDVYVYFNNDAEGHAPANALALAELLGAAG 241
DUF72 pfam01904
Protein of unknown function DUF72; The function of this family is unknown.
22-266 1.15e-74

Protein of unknown function DUF72; The function of this family is unknown.


Pssm-ID: 426503  Cd Length: 220  Bit Score: 227.46  E-value: 1.15e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669   22 QTDKLKTYAGHFPVVELDATYYAIQPERNILKWIKETPDTFEFVVKIHQALTLHADYKTFAdtRQELFDQFKNMLEPLHt 101
Cdd:pfam01904   1 QRERLEYYARHFNTVEINSTFYRLPSPETVARWAEQTPDGFRFSVKAPRFITHRKRLRDLD--AEEALARFLEALEPLG- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  102 qKKLAMVLVQFPPWFDCNAQNIKYILYVRQQL-QSFPMCVEFRHQSWFSDAFkeqtLSFLTEHQIIHAVVDEPqvKDGSV 180
Cdd:pfam01904  78 -GKLGPLLFQLPPSFKFDPENLERLEAFLALLpRGLRLAVEFRHPSWFTPEV----LELLREHGVALVVADEP--SPGRL 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  181 PLVNRITNEIAFVRYHGRNHYGWtkkdmsdqewrdvrylYDYNEQELIDLAQKAQILAQKAKKVYVIFNNNSGGHAANNA 260
Cdd:pfam01904 151 PPEDVTTADFAYVRLHGRNELYW----------------YRYSDEELDEWAERIRAWAAEGRDVYVFFNNDAEGHAPLNA 214

                  ....*.
gi 616721669  261 KTYQRL 266
Cdd:pfam01904 215 RRLAEL 220
PRK10302 PRK10302
hypothetical protein; Provisional
1-157 9.00e-06

hypothetical protein; Provisional


Pssm-ID: 182366  Cd Length: 272  Bit Score: 46.17  E-value: 9.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669   1 MINIGLTGWgdHYSLYEDLERQTdkLKTYAGHFPVVELDATYYAIQPERNILKWIKETPDTFEFVVKI-----HQALTLH 75
Cdd:PRK10302   1 MIYIGLPQW--QHPKWVRLGITS--LEDYARHFNCVEGNTTLYALPKPEIVLRWRDMTTDDFRFCFKFpatisHQAALRH 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616721669  76 ADyktfadtrqELFDQFKNMLEPLHTqkKLAMVLVQFPPWF---DCNAqnikyiLYvrQQLQSFP----MCVEFRHQSWF 148
Cdd:PRK10302  77 CD---------DLVQEFFTRLAPLAD--RIGQYWLQLPAAFgprELPA------LW--QFLDALPagftYGVEVRHPEFF 137

                 ....*....
gi 616721669 149 SDAFKEQTL 157
Cdd:PRK10302 138 AKGEAEQAL 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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