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Conserved domains on  [gi|1964382717|gb|KAG2226717|]
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hypothetical protein INT45_001064 [Circinella minor]

Protein Classification

GATA-type transcription factor( domain architecture ID 10554027)

GATA-type transcription factor containing a DUF1752 domain, binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
Gene Ontology:  GO:0003700|GO:0006357|GO:0008270|GO:0043565
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 506-556 2.65e-23

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 93.21  E-value: 2.65e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1964382717 506 KCTNCGTTTTPLWRRNPAGQ-PLCNACGLFLKLHGVVRPLSLKT-DIIKKRNR 556
Cdd:cd00202     1 ACSNCGTTTTPLWRRGPSGGsTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNR 53
DUF1752 pfam08550
Fungal protein of unknown function (DUF1752); This is a family of fungal proteins of unknown ...
 71-98 5.12e-13

Fungal protein of unknown function (DUF1752); This is a family of fungal proteins of unknown function. This short section domain is bounded by two highly conserved tryptophans. The family contains Swiss:P34072 that is thought to be a negative regulator of RAS-cAMP pathway in S.cerevisiae. the Sch.pombe member is a GAF1 transcription factor Swiss:Q10280 that is also associated with the zinc finger family GATA pfam00320.


:

Pssm-ID: 430068  Cd Length: 28  Bit Score: 63.63  E-value: 5.12e-13
                          10        20
                  ....*....|....*....|....*...
gi 1964382717  71 VWRMYTKAKDTLPNGARMENLTWRMMAM 98
Cdd:pfam08550   1 LWKVYTKCKDSLPNGERLENLSWRLWNK 28
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 506-556 2.65e-23

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 93.21  E-value: 2.65e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1964382717 506 KCTNCGTTTTPLWRRNPAGQ-PLCNACGLFLKLHGVVRPLSLKT-DIIKKRNR 556
Cdd:cd00202     1 ACSNCGTTTTPLWRRGPSGGsTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNR 53
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
507-551 3.58e-19

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 81.70  E-value: 3.58e-19
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1964382717  507 CTNCGTTTTPLWRRNPAGQ-PLCNACGLFLKLHGVV-RPLSLKTDII 551
Cdd:smart00401   6 CSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGLkRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 507-540 9.08e-17

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 74.28  E-value: 9.08e-17
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1964382717 507 CTNCGTTTTPLWRRNPAGQP-LCNACGLFLKLHGV 540
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
DUF1752 pfam08550
Fungal protein of unknown function (DUF1752); This is a family of fungal proteins of unknown ...
 71-98 5.12e-13

Fungal protein of unknown function (DUF1752); This is a family of fungal proteins of unknown function. This short section domain is bounded by two highly conserved tryptophans. The family contains Swiss:P34072 that is thought to be a negative regulator of RAS-cAMP pathway in S.cerevisiae. the Sch.pombe member is a GAF1 transcription factor Swiss:Q10280 that is also associated with the zinc finger family GATA pfam00320.


Pssm-ID: 430068  Cd Length: 28  Bit Score: 63.63  E-value: 5.12e-13
                          10        20
                  ....*....|....*....|....*...
gi 1964382717  71 VWRMYTKAKDTLPNGARMENLTWRMMAM 98
Cdd:pfam08550   1 LWKVYTKCKDSLPNGERLENLSWRLWNK 28
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
503-556 2.15e-03

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 41.40  E-value: 2.15e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1964382717 503 NKTKCTNCGTT--TTPLWRRNPAGQPLCNACGLFLKLHGVVRPLSLKTDIIKKRNR 556
Cdd:COG5641   296 SDKKRSTLTTStaTPLWRRTSDKSSFSCNASGSALKPPGSKRPLLPKPDPNSKRSN 351
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 506-556 2.65e-23

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 93.21  E-value: 2.65e-23
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1964382717 506 KCTNCGTTTTPLWRRNPAGQ-PLCNACGLFLKLHGVVRPLSLKT-DIIKKRNR 556
Cdd:cd00202     1 ACSNCGTTTTPLWRRGPSGGsTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNR 53
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
507-551 3.58e-19

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 81.70  E-value: 3.58e-19
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1964382717  507 CTNCGTTTTPLWRRNPAGQ-PLCNACGLFLKLHGVV-RPLSLKTDII 551
Cdd:smart00401   6 CSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHGGLkRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 507-540 9.08e-17

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 74.28  E-value: 9.08e-17
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1964382717 507 CTNCGTTTTPLWRRNPAGQP-LCNACGLFLKLHGV 540
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
DUF1752 pfam08550
Fungal protein of unknown function (DUF1752); This is a family of fungal proteins of unknown ...
 71-98 5.12e-13

Fungal protein of unknown function (DUF1752); This is a family of fungal proteins of unknown function. This short section domain is bounded by two highly conserved tryptophans. The family contains Swiss:P34072 that is thought to be a negative regulator of RAS-cAMP pathway in S.cerevisiae. the Sch.pombe member is a GAF1 transcription factor Swiss:Q10280 that is also associated with the zinc finger family GATA pfam00320.


Pssm-ID: 430068  Cd Length: 28  Bit Score: 63.63  E-value: 5.12e-13
                          10        20
                  ....*....|....*....|....*...
gi 1964382717  71 VWRMYTKAKDTLPNGARMENLTWRMMAM 98
Cdd:pfam08550   1 LWKVYTKCKDSLPNGERLENLSWRLWNK 28
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
503-556 2.15e-03

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 41.40  E-value: 2.15e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1964382717 503 NKTKCTNCGTT--TTPLWRRNPAGQPLCNACGLFLKLHGVVRPLSLKTDIIKKRNR 556
Cdd:COG5641   296 SDKKRSTLTTStaTPLWRRTSDKSSFSCNASGSALKPPGSKRPLLPKPDPNSKRSN 351
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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