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Conserved domains on  [gi|2050310029|gb|KAG6736519|]
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hypothetical protein POTOM_060623 [Populus tomentosa]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02983 PLN02983
biotin carboxyl carrier protein of acetyl-CoA carboxylase
 99-379 9.42e-137

biotin carboxyl carrier protein of acetyl-CoA carboxylase


:

Pssm-ID: 215533 [Multi-domain]  Cd Length: 274  Bit Score: 391.12  E-value: 9.42e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029  99 MASISVPCPKTILVAAVVGS----NAQNSQPKPMVSFPRAPisnqnpplslgstfsgfewPNRKQQAVMKAQAQLNEVMV 174
Cdd:PLN02983    1 MASLSVPCAKTAAAAANVGSrlsrSSFRLQPKPNISFPSKG-------------------PNPKRSAVPKVKAQLNEVAV 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 175 EKSSNSVLVGDSESKAASSEGKDEP-----TESKIPDVPSISAFMTQVSELVKLVDSRDITELQLKQSGCELIIRKKEAL 249
Cdd:PLN02983   62 DGSSNSAKSDDPKSEVAPSEPKDEPpsnssSKPNLPDEESISEFMTQVSSLVKLVDSRDIVELQLKQLDCELVIRKKEAL 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 250 QQSEPAAPVLLMQPPYPHAMFPAPPIAAPAPAPASPSSAPALP---PPAKASSSSHPPLKCPMAGTFYRSPAPGEPPFVK 326
Cdd:PLN02983  142 PQPPPPAPVVMMQPPPPHAMPPASPPAAQPAPSAPASSPPPTPaspPPAKAPKSSHPPLKSPMAGTFYRSPAPGEPPFVK 221

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2050310029 327 VGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIAP 379
Cdd:PLN02983  222 VGDKVQKGQVVCIIEAMKLMNEIEADQSGTIVEILAEDGKPVSVDTPLFVIEP 274
 
Name Accession Description Interval E-value
PLN02983 PLN02983
biotin carboxyl carrier protein of acetyl-CoA carboxylase
 99-379 9.42e-137

biotin carboxyl carrier protein of acetyl-CoA carboxylase


Pssm-ID: 215533 [Multi-domain]  Cd Length: 274  Bit Score: 391.12  E-value: 9.42e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029  99 MASISVPCPKTILVAAVVGS----NAQNSQPKPMVSFPRAPisnqnpplslgstfsgfewPNRKQQAVMKAQAQLNEVMV 174
Cdd:PLN02983    1 MASLSVPCAKTAAAAANVGSrlsrSSFRLQPKPNISFPSKG-------------------PNPKRSAVPKVKAQLNEVAV 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 175 EKSSNSVLVGDSESKAASSEGKDEP-----TESKIPDVPSISAFMTQVSELVKLVDSRDITELQLKQSGCELIIRKKEAL 249
Cdd:PLN02983   62 DGSSNSAKSDDPKSEVAPSEPKDEPpsnssSKPNLPDEESISEFMTQVSSLVKLVDSRDIVELQLKQLDCELVIRKKEAL 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 250 QQSEPAAPVLLMQPPYPHAMFPAPPIAAPAPAPASPSSAPALP---PPAKASSSSHPPLKCPMAGTFYRSPAPGEPPFVK 326
Cdd:PLN02983  142 PQPPPPAPVVMMQPPPPHAMPPASPPAAQPAPSAPASSPPPTPaspPPAKAPKSSHPPLKSPMAGTFYRSPAPGEPPFVK 221

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2050310029 327 VGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIAP 379
Cdd:PLN02983  222 VGDKVQKGQVVCIIEAMKLMNEIEADQSGTIVEILAEDGKPVSVDTPLFVIEP 274
AccB COG0511
Biotin carboxyl carrier protein [Lipid transport and metabolism]; Biotin carboxyl carrier ...
 220-377 1.74e-42

Biotin carboxyl carrier protein [Lipid transport and metabolism]; Biotin carboxyl carrier protein is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440277 [Multi-domain]  Cd Length: 136  Bit Score: 145.04  E-value: 1.74e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 220 LVKLVDSRDITELQLKQSGCELIIRKKEALQQSEPAAPVllMQPPYPHAmfpappiaapapapaspssapALPPPAKASS 299
Cdd:COG0511     1 LIELLEESGLTELEVEEGEYKVRIKRGGAAAAAPVAAPA--AAAPAAAA---------------------PAAAAAAAAA 57

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2050310029 300 SSHPPLKCPMAGTFYRSPAPGEPPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:COG0511    58 SGGGAVKSPMVGTFYRAPSPGAKPFVKVGDKVKAGDTLCIIEAMKMMNEIEAPVSGTVVEILVENGQPVEYGQPLFVI 135
BCCP TIGR00531
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This model is designed to identify ...
 214-377 5.68e-38

acetyl-CoA carboxylase, biotin carboxyl carrier protein; This model is designed to identify biotin carboxyl carrier protein as a peptide of acetyl-CoA carboxylase. Scoring below the trusted cutoff is a related protein encoded in a region associated with polyketide synthesis in the prokaryote Saccharopolyspora hirsuta, and a reported chloroplast-encoded biotin carboxyl carrier protein that may be highly derived from the last common ancestral sequence. Scoring below the noise cutoff are biotin carboxyl carrier domains of other enzymes such as pyruvate carboxylase.The gene name is accB or fabE. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 273123 [Multi-domain]  Cd Length: 155  Bit Score: 133.81  E-value: 5.68e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 214 MTQVSELVKLVDSRDITELQLKQSGCELIIRKKEAL----QQSEPAAPVLLMQPPYPHAmfpappiaapapapasPSSAP 289
Cdd:TIGR00531   3 IREIKELIKLVEESGITELELKEEEFSVRLSKAAAAasfsVVQQAAAPVPAQVPAQSSA----------------AVPAP 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 290 ALPPPAKASSSSHPPLKCPMAGTFYRSPAPGEPPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVS 369
Cdd:TIGR00531  67 APAAPAPAADIKGHIVRSPMVGTFYRAPSPDAKPFVEVGDKVNKGQTVCIVEAMKMMNEIEAEKAGTVVAILVENGQPVE 146


                  ....*...
gi 2050310029 370 VDTPLFVI 377
Cdd:TIGR00531 147 YGEPLIVI 154
biotinyl_domain cd06850
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all ...
 305-377 2.16e-25

The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, oxaloacetate decarboxylase, methylmalonyl-CoA decarboxylase, transcarboxylase and urea amidolyase. This domain functions in transferring CO2 from one subsite to another, allowing carboxylation, decarboxylation, or transcarboxylation. During this process, biotin is covalently attached to a specific lysine.


Pssm-ID: 133459 [Multi-domain]  Cd Length: 67  Bit Score: 97.49  E-value: 2.16e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2050310029 305 LKCPMAGTFYRspapgepPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:cd06850     2 VTAPMPGTVVK-------VLVKEGDKVEAGQPLAVLEAMKMENEVTAPVAGVVKEILVKEGDQVEAGQLLVVI 67
Biotin_lipoyl pfam00364
Biotin-requiring enzyme; This family covers two Prosite entries, the conserved lysine residue ...
 303-377 1.19e-24

Biotin-requiring enzyme; This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognize the Glycine cleavage system H proteins.


Pssm-ID: 395290 [Multi-domain]  Cd Length: 73  Bit Score: 95.74  E-value: 1.19e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 303 PPLKCPMAGTFYRSPapGEPPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:pfam00364   1 TEIKSPMIGESVREG--VVEWLVKVGDKVKAGQPLAEVEAMKMEMEIPAPVAGVVKEILVPEGDTVEVGDPLAKI 73
 
Name Accession Description Interval E-value
PLN02983 PLN02983
biotin carboxyl carrier protein of acetyl-CoA carboxylase
 99-379 9.42e-137

biotin carboxyl carrier protein of acetyl-CoA carboxylase


Pssm-ID: 215533 [Multi-domain]  Cd Length: 274  Bit Score: 391.12  E-value: 9.42e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029  99 MASISVPCPKTILVAAVVGS----NAQNSQPKPMVSFPRAPisnqnpplslgstfsgfewPNRKQQAVMKAQAQLNEVMV 174
Cdd:PLN02983    1 MASLSVPCAKTAAAAANVGSrlsrSSFRLQPKPNISFPSKG-------------------PNPKRSAVPKVKAQLNEVAV 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 175 EKSSNSVLVGDSESKAASSEGKDEP-----TESKIPDVPSISAFMTQVSELVKLVDSRDITELQLKQSGCELIIRKKEAL 249
Cdd:PLN02983   62 DGSSNSAKSDDPKSEVAPSEPKDEPpsnssSKPNLPDEESISEFMTQVSSLVKLVDSRDIVELQLKQLDCELVIRKKEAL 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 250 QQSEPAAPVLLMQPPYPHAMFPAPPIAAPAPAPASPSSAPALP---PPAKASSSSHPPLKCPMAGTFYRSPAPGEPPFVK 326
Cdd:PLN02983  142 PQPPPPAPVVMMQPPPPHAMPPASPPAAQPAPSAPASSPPPTPaspPPAKAPKSSHPPLKSPMAGTFYRSPAPGEPPFVK 221

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2050310029 327 VGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIAP 379
Cdd:PLN02983  222 VGDKVQKGQVVCIIEAMKLMNEIEADQSGTIVEILAEDGKPVSVDTPLFVIEP 274
AccB COG0511
Biotin carboxyl carrier protein [Lipid transport and metabolism]; Biotin carboxyl carrier ...
 220-377 1.74e-42

Biotin carboxyl carrier protein [Lipid transport and metabolism]; Biotin carboxyl carrier protein is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440277 [Multi-domain]  Cd Length: 136  Bit Score: 145.04  E-value: 1.74e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 220 LVKLVDSRDITELQLKQSGCELIIRKKEALQQSEPAAPVllMQPPYPHAmfpappiaapapapaspssapALPPPAKASS 299
Cdd:COG0511     1 LIELLEESGLTELEVEEGEYKVRIKRGGAAAAAPVAAPA--AAAPAAAA---------------------PAAAAAAAAA 57

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2050310029 300 SSHPPLKCPMAGTFYRSPAPGEPPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:COG0511    58 SGGGAVKSPMVGTFYRAPSPGAKPFVKVGDKVKAGDTLCIIEAMKMMNEIEAPVSGTVVEILVENGQPVEYGQPLFVI 135
BCCP TIGR00531
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This model is designed to identify ...
 214-377 5.68e-38

acetyl-CoA carboxylase, biotin carboxyl carrier protein; This model is designed to identify biotin carboxyl carrier protein as a peptide of acetyl-CoA carboxylase. Scoring below the trusted cutoff is a related protein encoded in a region associated with polyketide synthesis in the prokaryote Saccharopolyspora hirsuta, and a reported chloroplast-encoded biotin carboxyl carrier protein that may be highly derived from the last common ancestral sequence. Scoring below the noise cutoff are biotin carboxyl carrier domains of other enzymes such as pyruvate carboxylase.The gene name is accB or fabE. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 273123 [Multi-domain]  Cd Length: 155  Bit Score: 133.81  E-value: 5.68e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 214 MTQVSELVKLVDSRDITELQLKQSGCELIIRKKEAL----QQSEPAAPVLLMQPPYPHAmfpappiaapapapasPSSAP 289
Cdd:TIGR00531   3 IREIKELIKLVEESGITELELKEEEFSVRLSKAAAAasfsVVQQAAAPVPAQVPAQSSA----------------AVPAP 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029 290 ALPPPAKASSSSHPPLKCPMAGTFYRSPAPGEPPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVS 369
Cdd:TIGR00531  67 APAAPAPAADIKGHIVRSPMVGTFYRAPSPDAKPFVEVGDKVNKGQTVCIVEAMKMMNEIEAEKAGTVVAILVENGQPVE 146


                  ....*...
gi 2050310029 370 VDTPLFVI 377
Cdd:TIGR00531 147 YGEPLIVI 154
biotinyl_domain cd06850
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all ...
 305-377 2.16e-25

The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, oxaloacetate decarboxylase, methylmalonyl-CoA decarboxylase, transcarboxylase and urea amidolyase. This domain functions in transferring CO2 from one subsite to another, allowing carboxylation, decarboxylation, or transcarboxylation. During this process, biotin is covalently attached to a specific lysine.


Pssm-ID: 133459 [Multi-domain]  Cd Length: 67  Bit Score: 97.49  E-value: 2.16e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2050310029 305 LKCPMAGTFYRspapgepPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:cd06850     2 VTAPMPGTVVK-------VLVKEGDKVEAGQPLAVLEAMKMENEVTAPVAGVVKEILVKEGDQVEAGQLLVVI 67
Biotin_lipoyl pfam00364
Biotin-requiring enzyme; This family covers two Prosite entries, the conserved lysine residue ...
 303-377 1.19e-24

Biotin-requiring enzyme; This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognize the Glycine cleavage system H proteins.


Pssm-ID: 395290 [Multi-domain]  Cd Length: 73  Bit Score: 95.74  E-value: 1.19e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 303 PPLKCPMAGTFYRSPapGEPPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:pfam00364   1 TEIKSPMIGESVREG--VVEWLVKVGDKVKAGQPLAEVEAMKMEMEIPAPVAGVVKEILVPEGDTVEVGDPLAKI 73
PRK09282 PRK09282
pyruvate carboxylase subunit B; Validated
 304-379 3.04e-24

pyruvate carboxylase subunit B; Validated


Pssm-ID: 236449 [Multi-domain]  Cd Length: 592  Bit Score: 104.15  E-value: 3.04e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2050310029 304 PLKCPMAGTFYRSpapgeppFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIAP 379
Cdd:PRK09282  524 AVTSPMPGTVVKV-------KVKEGDKVKAGDTVLVLEAMKMENEIQAPVDGTVKEILVKEGDRVNPGDVLMEIEP 592
PRK07051 PRK07051
biotin carboxyl carrier domain-containing protein;
305-378 2.54e-21

biotin carboxyl carrier domain-containing protein;


Pssm-ID: 180811 [Multi-domain]  Cd Length: 80  Bit Score: 86.99  E-value: 2.54e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2050310029 305 LKCPMAGTFYRSPAPGEPPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIA 378
Cdd:PRK07051    6 IVSPLPGTFYRRPSPDAPPYVEVGDAVAAGDVVGLIEVMKQFTEVEAEAAGRVVEFLVEDGEPVEAGQVLARIE 79
AceF COG0508
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component ...
 324-378 2.03e-14

Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component [Energy production and conversion]; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440274 [Multi-domain]  Cd Length: 77  Bit Score: 67.78  E-value: 2.03e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 324 FVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIA 378
Cdd:COG0508    23 LVKEGDTVKEGDPLAEVETDKATMEVPAPAAGVLLEILVKEGDTVPVGAVIAVIA 77
Biotinyl_lipoyl_domains cd06663
Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the ...
 310-377 3.52e-14

Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl, or methylamine, respectively, between components of the complex/protein via a biotinyl or lipoyl group, which is covalently attached to a highly conserved lysine residue.


Pssm-ID: 133456 [Multi-domain]  Cd Length: 73  Bit Score: 67.08  E-value: 3.52e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2050310029 310 AGTFYRSpapgeppFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:cd06663    13 DGTVVKW-------LKKVGDKVKKGDVLAEIEAMKATSDVEAPKSGTVKKVLVKEGTKVEGDTPLVKI 73
lipoyl_domain cd06849
Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. ...
 324-377 3.56e-14

Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid dehydrogenase (BCDH), contain at least three different enzymes, 2-oxo acid dehydrogenase (E1), dihydrolipoyl acyltransferase (E2) and dihydrolipoamide dehydrogenase (E3) and play a key role in redox regulation. E2, the central component of the complex, catalyzes the transfer of the acyl group of CoA from E1 to E3 via reductive acetylation of a lipoyl group covalently attached to a lysine residue.


Pssm-ID: 133458 [Multi-domain]  Cd Length: 74  Bit Score: 67.04  E-value: 3.56e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2050310029 324 FVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:cd06849    21 LVKEGDSVEEGDVLAEVETDKATVEVEAPAAGVLAKILVEEGDTVPVGQVIAVI 74
PRK14040 PRK14040
oxaloacetate decarboxylase subunit alpha;
304-378 3.01e-12

oxaloacetate decarboxylase subunit alpha;


Pssm-ID: 237592 [Multi-domain]  Cd Length: 593  Bit Score: 68.03  E-value: 3.01e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 304 PLKCPMAGTFYRSpapgeppFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIA 378
Cdd:PRK14040  526 PVTAPLAGNIFKV-------IVTEGQTVAEGDVLLILEAMKMETEIRAAQAGTVRGIAVKEGDAVAVGDTLLTLA 593
PRK11856 PRK11856
branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed
 324-378 1.13e-10

branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed


Pssm-ID: 237001 [Multi-domain]  Cd Length: 411  Bit Score: 62.50  E-value: 1.13e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 324 FVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIA 378
Cdd:PRK11856   23 LVKVGDTVKEGQPLAEVETDKATVEIPSPVAGTVAKLLVEEGDVVPVGSVIAVIE 77
PycA COG1038
Pyruvate carboxylase [Energy production and conversion]; Pyruvate carboxylase is part of the ...
 308-377 1.37e-09

Pyruvate carboxylase [Energy production and conversion]; Pyruvate carboxylase is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440660 [Multi-domain]  Cd Length: 1144  Bit Score: 60.09  E-value: 1.37e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2050310029  308 PMAGTFYRspapgepPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:COG1038   1082 PMPGTVVK-------VLVKEGDEVKKGDPLLTIEAMKMETTITAPRDGTVKEVLVKEGDQVEAGDLLIEL 1144
PRK08225 PRK08225
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 309-365 6.98e-09

acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


Pssm-ID: 181304 [Multi-domain]  Cd Length: 70  Bit Score: 52.10  E-value: 6.98e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2050310029 309 MAGTFYRSpapgeppFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDG 365
Cdd:PRK08225    8 MAGNVWKI-------VVKVGDTVEEGQDVVILESMKMEIPIVAEEAGTVKKINVQEG 57
PTZ00144 PTZ00144
dihydrolipoamide succinyltransferase; Provisional
 325-379 7.31e-09

dihydrolipoamide succinyltransferase; Provisional


Pssm-ID: 240289 [Multi-domain]  Cd Length: 418  Bit Score: 57.00  E-value: 7.31e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 325 VKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIAP 379
Cdd:PTZ00144   66 KKVGDYVKEDEVICIIETDKVSVDIRAPASGVITKIFAEEGDTVEVGAPLSEIDT 120
PRK12999 PRK12999
pyruvate carboxylase; Reviewed
 308-379 2.07e-08

pyruvate carboxylase; Reviewed


Pssm-ID: 237263 [Multi-domain]  Cd Length: 1146  Bit Score: 56.30  E-value: 2.07e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2050310029  308 PMAGTFYRspapgepPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIAP 379
Cdd:PRK12999  1082 PMPGSVVT-------VLVKEGDEVKAGDPLAVIEAMKMETTITAPVDGTVKRVLVKAGDQVEAGDLLVELEP 1146
PRK06549 PRK06549
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 316-378 3.07e-08

acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


Pssm-ID: 235826 [Multi-domain]  Cd Length: 130  Bit Score: 51.74  E-value: 3.07e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 316 SPAPGE--PPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIA 378
Cdd:PRK06549   66 SPMPGTilKVLVAVGDQVTENQPLLILEAMKMENEIVASSAGTVTAIHVTPGQVVNPGDGLITIG 130
sucB TIGR01347
2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This ...
 326-378 5.91e-07

2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This model describes the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. The seed for this model includes mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N-terminus. They score below the trusted cutoff, but above the noise cutoff and above all examples of dihydrolipoamide acetyltransferase. [Energy metabolism, TCA cycle]


Pssm-ID: 273565 [Multi-domain]  Cd Length: 403  Bit Score: 50.89  E-value: 5.91e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2050310029 326 KVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIA 378
Cdd:TIGR01347  23 KVGDTVKRDENIVEIETDKVVLEVPSPADGVLQEILFKEGDTVESGQVLAILE 75
PRK05641 PRK05641
putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 316-374 1.49e-06

putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


Pssm-ID: 235540 [Multi-domain]  Cd Length: 153  Bit Score: 47.55  E-value: 1.49e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2050310029 316 SPAPGE--PPFVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPL 374
Cdd:PRK05641   89 APMPGKilRILVREGQQVKVGQGLLILEAMKMENEIPAPKDGVVKKILVKEGDTVDTGQPL 149
PRK05704 PRK05704
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase;
324-379 3.36e-06

2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase;


Pssm-ID: 235571 [Multi-domain]  Cd Length: 407  Bit Score: 48.68  E-value: 3.36e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2050310029 324 FVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVIAP 379
Cdd:PRK05704   23 HKKPGDAVKRDEVLVEIETDKVVLEVPAPAAGVLSEILAEEGDTVTVGQVLGRIDE 78
PRK14042 PRK14042
pyruvate carboxylase subunit B; Provisional
 325-369 2.63e-05

pyruvate carboxylase subunit B; Provisional


Pssm-ID: 172536 [Multi-domain]  Cd Length: 596  Bit Score: 46.25  E-value: 2.63e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2050310029 325 VKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVS 369
Cdd:PRK14042  541 VSAGDEVKAGQAVLVIEAMKMETEIKAPANGVVAEILCQKGDKVT 585
PRK11855 PRK11855
dihydrolipoamide acetyltransferase; Reviewed
 324-377 9.23e-05

dihydrolipoamide acetyltransferase; Reviewed


Pssm-ID: 237000 [Multi-domain]  Cd Length: 547  Bit Score: 44.43  E-value: 9.23e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2050310029 324 FVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:PRK11855   22 LVKEGDTVEEDQPLVTVETDKATMEIPSPAAGVVKEIKVKVGDTVSVGGLLAVI 75
PRK11855 PRK11855
dihydrolipoamide acetyltransferase; Reviewed
 324-377 1.09e-04

dihydrolipoamide acetyltransferase; Reviewed


Pssm-ID: 237000 [Multi-domain]  Cd Length: 547  Bit Score: 44.04  E-value: 1.09e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2050310029 324 FVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:PRK11855  139 LVKVGDTVEEDQSLITVETDKATMEIPSPVAGVVKEIKVKVGDKVSVGSLLVVI 192
PRK11892 PRK11892
pyruvate dehydrogenase subunit beta; Provisional
 325-378 2.43e-04

pyruvate dehydrogenase subunit beta; Provisional


Pssm-ID: 237011 [Multi-domain]  Cd Length: 464  Bit Score: 42.98  E-value: 2.43e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2050310029 325 VKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEI-VAEDGKPVSVDTPLFVIA 378
Cdd:PRK11892   24 KKEGDKVKSGDVIAEIETDKATMEVEAVDEGTLGKIlVPEGTEGVKVNTPIAVLL 78
aceF PRK11854
pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated
 324-377 1.68e-03

pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated


Pssm-ID: 236999 [Multi-domain]  Cd Length: 633  Bit Score: 40.37  E-value: 1.68e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2050310029 324 FVKVGDKVQKGQVVCIIEAMKLMNEIEADQSGTITEIVAEDGKPVSVDTPLFVI 377
Cdd:PRK11854   21 LVKVGDKVEAEQSLITVEGDKASMEVPSPQAGVVKEIKVKVGDKVETGALIMIF 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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