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Conserved domains on  [gi|2448837752|gb|KAJ5875758|]
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hypothetical protein N7473_013105 [Penicillium subrubescens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
transpos_IS630 super family cl41314
IS630 family transposase;
23-61 6.13e-06

IS630 family transposase;


The actual alignment was detected with superfamily member NF033545:

Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 41.09  E-value: 6.13e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2448837752  23 QRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKRFNEG 39
 
Name Accession Description Interval E-value
transpos_IS630 NF033545
IS630 family transposase;
23-61 6.13e-06

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 41.09  E-value: 6.13e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2448837752  23 QRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKRFNEG 39
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
22-61 9.19e-06

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 40.61  E-value: 9.19e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2448837752  22 EQRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:COG3415    26 ARRLRAVLLLAEGLSVREIAERLGVSRSTVYRWLKRYREG 65
HTH_Hin_like cd00569
Helix-turn-helix domain of Hin and related proteins; This domain model summarizes a family of ...
16-55 1.13e-04

Helix-turn-helix domain of Hin and related proteins; This domain model summarizes a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed helical bundle. The principal DNA-protein interface is formed by the third helix, the recognition helix, inserting itself into the major groove of the DNA. A diverse array of HTH domains participate in a variety of functions that depend on their DNA-binding properties. HTH_Hin represents one of the simplest versions of the HTH domains; the characterization of homologous relationships between various sequence-diverse HTH domain families remains difficult. The Hin recombinase induces the site-specific inversion of a chromosomal DNA segment containing a promoter, which controls the alternate expression of two genes by reversibly switching orientation. The Hin recombinase consists of a single polypeptide chain containing a C-terminal DNA-binding domain (HTH_Hin) and a catalytic domain.


Pssm-ID: 259851 [Multi-domain]  Cd Length: 42  Bit Score: 34.99  E-value: 1.13e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 2448837752 16 KAELSTEQRSAIIIALEGGGSPTVLATQFGCARSTIYDTL 55
Cdd:cd00569    3 PPKLTPEQIAEARRLLAAGESVAEIARELGVSRSTLYRYL 42
HTH_23 pfam13384
Homeodomain-like domain;
19-61 2.41e-04

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 34.55  E-value: 2.41e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 2448837752 19 LSTEQRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:pfam13384  2 ARERRRARALLLLAEGLSVKEIAELLGVSRRTVYRWLKRYNEE 44
 
Name Accession Description Interval E-value
transpos_IS630 NF033545
IS630 family transposase;
23-61 6.13e-06

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 41.09  E-value: 6.13e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2448837752  23 QRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKRFNEG 39
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
22-61 9.19e-06

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 40.61  E-value: 9.19e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2448837752  22 EQRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:COG3415    26 ARRLRAVLLLAEGLSVREIAERLGVSRSTVYRWLKRYREG 65
HTH_Hin_like cd00569
Helix-turn-helix domain of Hin and related proteins; This domain model summarizes a family of ...
16-55 1.13e-04

Helix-turn-helix domain of Hin and related proteins; This domain model summarizes a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed helical bundle. The principal DNA-protein interface is formed by the third helix, the recognition helix, inserting itself into the major groove of the DNA. A diverse array of HTH domains participate in a variety of functions that depend on their DNA-binding properties. HTH_Hin represents one of the simplest versions of the HTH domains; the characterization of homologous relationships between various sequence-diverse HTH domain families remains difficult. The Hin recombinase induces the site-specific inversion of a chromosomal DNA segment containing a promoter, which controls the alternate expression of two genes by reversibly switching orientation. The Hin recombinase consists of a single polypeptide chain containing a C-terminal DNA-binding domain (HTH_Hin) and a catalytic domain.


Pssm-ID: 259851 [Multi-domain]  Cd Length: 42  Bit Score: 34.99  E-value: 1.13e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 2448837752 16 KAELSTEQRSAIIIALEGGGSPTVLATQFGCARSTIYDTL 55
Cdd:cd00569    3 PPKLTPEQIAEARRLLAAGESVAEIARELGVSRSTLYRYL 42
HTH_23 pfam13384
Homeodomain-like domain;
19-61 2.41e-04

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 34.55  E-value: 2.41e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 2448837752 19 LSTEQRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:pfam13384  2 ARERRRARALLLLAEGLSVKEIAELLGVSRRTVYRWLKRYNEE 44
Tra8 COG2826
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
19-57 5.47e-04

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 35.63  E-value: 5.47e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2448837752  19 LSTEQRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKR 57
Cdd:COG2826     7 LTLEEREEIEALLKAGLSVREIARRLGRSPSTISRELKR 45
HTH_29 pfam13551
Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is ...
26-61 1.03e-03

Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.


Pssm-ID: 433301 [Multi-domain]  Cd Length: 64  Bit Score: 33.11  E-value: 1.03e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 2448837752 26 AIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:pfam13551  4 ALLLLAEGVSTVSQAARLLGLSRRTVYRWLKRFNEG 39
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
23-61 5.92e-03

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 31.02  E-value: 5.92e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 2448837752 23 QRSAIIIALEGGGSPTVLATQFGCARSTIYDTLKRFQQH 61
Cdd:pfam13518  1 ERLKIVLLALEGESIKEAARLFGISRSTVYRWIRRYREG 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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