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Conserved domains on  [gi|640932300|gb|KDN74825|]
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peptidase P60 [Streptomyces olindensis]

Protein Classification

bifunctional lytic transglycosylase/C40 family peptidase( domain architecture ID 12989902)

bifunctional lytic transglycosylase/C40 family peptidase may catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), and/or cleave peptide cross-bridges between glycan chains

Gene Ontology:  GO:0008233|GO:0016787|GO:0006508
MEROPS:  C40
PubMed:  12620121|11517925|8765311|7479697

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NlpC COG0791
Cell wall-associated hydrolase, NlpC_P60 family [Cell wall/membrane/envelope biogenesis];
107-313 2.51e-43

Cell wall-associated hydrolase, NlpC_P60 family [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440554 [Multi-domain]  Cd Length: 218  Bit Score: 148.69  E-value: 2.51e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 107 DVWDPEDAIPSSAKYLCTIAEDVKDVPGNKQSNMLAAYNAGSGAVRKYGGIPPY----KETQGYVRAITSLANKNSGGGA 182
Cdd:COG0791   14 AAAALAAVAAAGALAAADAAVAAALVAAAAAVLAAAALLAGPAAAVAGAAAPAVgsagAAAAAAAAKAGSSAAKSAAGAS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 183 PATADQGVTALNAAQKMLGKPYSWGGgnaNGPSkgtccspkgrsgasitGFDCSGLTLYAYAKAGIALPRTAAQQYAASE 262
Cdd:COG0791   94 APPSSTAEAIVAAALSYLGTPYVWGG---TSPS----------------GFDCSGLVQYVYRQAGISLPRTSADQAAAGT 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 640932300 263 PIKHDQAKPGDLVFYGASASGIHHVGIYVGGGYMLDAPRPGTQVRFSPLDS 313
Cdd:COG0791  155 PVSRSELQPGDLVFFRTGGGGISHVGIYLGNGKFIHASSSGKGVRISSLDS 205
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 31-175 6.20e-32

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 119.71  E-value: 6.20e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  31 AGTALSLAVPAQYQSMIEDAGNTcPEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGID-GNGDGKRDVW 109
Cdd:COG0741   91 ALAALLLRRPLPYLPLIEEAAKK-YGVDPALVLALIRQESAFNPNAVSPAGARGLMQLMPATARRLGLKlGLGPSPDDLF 169

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640932300 110 DPEDAIPSSAKYLctiaEDVKDVPGNKQSNMLAAYNAGSGAVRKY--------GGIPPYKETQGYVRAITSLAN 175
Cdd:COG0741  170 DPETNIRAGAAYL----RELLDRFDGDLVLALAAYNAGPGRVRRWlrrngdrdGEIIPYAETRNYVKKVLANYA 239
 
Name Accession Description Interval E-value
NlpC COG0791
Cell wall-associated hydrolase, NlpC_P60 family [Cell wall/membrane/envelope biogenesis];
107-313 2.51e-43

Cell wall-associated hydrolase, NlpC_P60 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440554 [Multi-domain]  Cd Length: 218  Bit Score: 148.69  E-value: 2.51e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 107 DVWDPEDAIPSSAKYLCTIAEDVKDVPGNKQSNMLAAYNAGSGAVRKYGGIPPY----KETQGYVRAITSLANKNSGGGA 182
Cdd:COG0791   14 AAAALAAVAAAGALAAADAAVAAALVAAAAAVLAAAALLAGPAAAVAGAAAPAVgsagAAAAAAAAKAGSSAAKSAAGAS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 183 PATADQGVTALNAAQKMLGKPYSWGGgnaNGPSkgtccspkgrsgasitGFDCSGLTLYAYAKAGIALPRTAAQQYAASE 262
Cdd:COG0791   94 APPSSTAEAIVAAALSYLGTPYVWGG---TSPS----------------GFDCSGLVQYVYRQAGISLPRTSADQAAAGT 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 640932300 263 PIKHDQAKPGDLVFYGASASGIHHVGIYVGGGYMLDAPRPGTQVRFSPLDS 313
Cdd:COG0791  155 PVSRSELQPGDLVFFRTGGGGISHVGIYLGNGKFIHASSSGKGVRISSLDS 205
Slt35-like cd13399
Slt35-like lytic transglycosylase; Lytic transglycosylase similar to Escherichia coli lytic ...
 55-176 3.53e-42

Slt35-like lytic transglycosylase; Lytic transglycosylase similar to Escherichia coli lytic transglycosylase Slt35 and Pseudomonas aeruginosa Sltb1. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).


Pssm-ID: 381602 [Multi-domain]  Cd Length: 108  Bit Score: 142.06  E-value: 3.53e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  55 PEVSPNLLAALLTQESGFNPKA-SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVWDPEDAIPSSAKYLCTIAEDVKDVP 133
Cdd:cd13399    1 YGVPPGILAAILGVESGFGPNAgGSPAGAQGIAQFMPSTWKAYGVDGNGDGKADPFNPEDAIASAANYLCRHGWDLNAFL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 640932300 134 GNKQSNMLAAYNAGSGavrkyggippyketqGYVRAITSLANK 176
Cdd:cd13399   81 GEDNFLALAAYNAGPG---------------AYANAVLELAAT 108
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 31-175 6.20e-32

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 119.71  E-value: 6.20e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  31 AGTALSLAVPAQYQSMIEDAGNTcPEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGID-GNGDGKRDVW 109
Cdd:COG0741   91 ALAALLLRRPLPYLPLIEEAAKK-YGVDPALVLALIRQESAFNPNAVSPAGARGLMQLMPATARRLGLKlGLGPSPDDLF 169

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640932300 110 DPEDAIPSSAKYLctiaEDVKDVPGNKQSNMLAAYNAGSGAVRKY--------GGIPPYKETQGYVRAITSLAN 175
Cdd:COG0741  170 DPETNIRAGAAYL----RELLDRFDGDLVLALAAYNAGPGRVRRWlrrngdrdGEIIPYAETRNYVKKVLANYA 239
NLPC_P60 pfam00877
NlpC/P60 family; The function of this domain is unknown. It is found in several lipoproteins.
 201-313 7.23e-30

NlpC/P60 family; The function of this domain is unknown. It is found in several lipoproteins.


Pssm-ID: 395705 [Multi-domain]  Cd Length: 105  Bit Score: 109.68  E-value: 7.23e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  201 GKPYSWGGGnangpskgtccspkgrsgaSITGFDCSGLTLYAYAKAGIALPRTAAQQYAA-SEPIKHDQAKPGDLVFYGa 279
Cdd:pfam00877   1 GVPYRWGGG-------------------SPSGFDCSGLVRYAFAKVGIELPRSSGQQYNAgKKTIPKSEPQRGDLVFFG- 60

                          90       100       110
                  ....*....|....*....|....*....|....
gi 640932300  280 SASGIHHVGIYVGGGYMLDAPrPGTQVRFSPLDS 313
Cdd:pfam00877  61 TGKGISHVGIYLGNGQMLHAS-TGGGVSISSLNG 93
PRK13914 PRK13914
invasion associated endopeptidase;
171-305 6.01e-29

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 116.05  E-value: 6.01e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 171 TSLANKNSGGGAPATADQGVTALNAAQKMLGKPYSWGGgnaNGPskgtccspkgrsgasiTGFDCSGLTLYAYAKAGIAL 250
Cdd:PRK13914 348 NSNTNANQGSSNNNSNSSASAIIAEAQKHLGKAYSWGG---NGP----------------TTFDCSGYTKYVFAKAGISL 408

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 640932300 251 PRTAAQQYAASEPIKHDQAKPGDLVFYGaSASGIHHVGIYVGGGYMLDAPRPGTQ 305
Cdd:PRK13914 409 PRTSGAQYASTTRISESQAKPGDLVFFD-YGSGISHVGIYVGNGQMINAQDNGVK 462
NlpC_inact_RipD NF033743
NlpC/P60 family peptidoglycan-binding protein RipD; RipD proteins, such as founding member ...
 201-310 4.74e-27

NlpC/P60 family peptidoglycan-binding protein RipD; RipD proteins, such as founding member Rv1566c from Mycobacterium tuberculosis, is a catalytically inactive paralog of the peptidoglycan endopeptidases RipA and RipB. A catalytically important Cys and His pair is replaced by Ala-83 and Ser-132.


Pssm-ID: 468164 [Multi-domain]  Cd Length: 177  Bit Score: 104.77  E-value: 4.74e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 201 GKPYSWGGGNANGPSKGTCCSPK---------GRSGASITGFDCSGLTLYAYAKAGIALPRTAAQQYAASEPIKHDQAKP 271
Cdd:NF033743  48 GVPFSYGGGNANGPTRGTGAGPAalnlpgaapGAPGPNVVGFDASGLMVYAFAGAGVKLPRSSGEQYKVGQKVLPAQALP 127

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 640932300 272 GDLVFYGasASGIHHVGIYVGGGYMLDAPRPGTQVrfSP 310
Cdd:NF033743 128 GDLIFYG--PEGTQSVALFLGNGQMLEATDPGVTV--SP 162
SLT_2 pfam13406
Transglycosylase SLT domain; This family is related to the SLT domain pfam01464.
 61-122 3.66e-16

Transglycosylase SLT domain; This family is related to the SLT domain pfam01464.


Pssm-ID: 404311 [Multi-domain]  Cd Length: 292  Bit Score: 77.59  E-value: 3.66e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640932300   61 LLAAL-LTQESGFNPKA--SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVWD-PEDAIPSSAKYL 122
Cdd:pfam13406 131 LIAALkILDRGDLDPEQlkGSWAGAMGQTQFMPSSYLAYAVDFDGDGRRDLWNsPPDALASVANYL 196
PRK11619 PRK11619
lytic murein transglycosylase; Provisional
 37-168 4.52e-12

lytic murein transglycosylase; Provisional


Pssm-ID: 183236 [Multi-domain]  Cd Length: 644  Bit Score: 66.62  E-value: 4.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  37 LAVPAQYQSMIEDAGntcpeVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTwETH-----GIDGNGDGKRdVWDP 111
Cdd:PRK11619 477 LAWNDEFRRYTSGKG-----IPQSYAMAIARQESAWNPKARSPVGASGLMQIMPGT-ATHtvkmfSIPGYSSSSQ-LLDP 549

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 640932300 112 EDAIPSSAKYLctiaEDVKDVPGNKQSNMLAAYNAGSGAVRKYGG--------------IpPYKETQGYVR 168
Cdd:PRK11619 550 ETNINIGTSYL----EYVYQQFGNNRILASAAYNAGPGRVRTWLGnsagridavafvesI-PFSETRGYVK 615
MltB_2 TIGR02283
lytic murein transglycosylase; Members of this family are closely related to the MltB family ...
 61-122 6.39e-12

lytic murein transglycosylase; Members of this family are closely related to the MltB family lytic murein transglycosylases described by TIGR02282 and are likewise all proteobacterial, although that family and this one form clearly distinct clades. Several species have one member of each family. Many members of this family (unlike the MltB family) contain an additional C-terminal domain, a putative peptidoglycan binding domain (pfam01471), not included in region described by this model. Many sequences appear to contain N-terminal lipoprotein attachment sites, as does E. coli MltB in TIGR02282. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 274067 [Multi-domain]  Cd Length: 300  Bit Score: 65.09  E-value: 6.39e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640932300   61 LLAALLTQESGFNPKA---SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVW-DPEDAIPSSAKYL 122
Cdd:TIGR02283 132 LIAALKILQRGDLTRAamkGSWAGAMGQTQFLPSSYLNYAVDFDGDGRRDIWnSVPDALASTANYL 197
Lyz-like cd00442
lysozyme-like domains; This family contains several members, including soluble lytic ...
 62-121 1.53e-09

lysozyme-like domains; This family contains several members, including soluble lytic transglycosylases (SLT), goose egg-white lysozymes (GEWL), hen egg-white lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, chitosanases, and pesticin. Typical members are involved in the hydrolysis of beta-1,4- linked polysaccharides.


Pssm-ID: 381596 [Multi-domain]  Cd Length: 59  Bit Score: 53.18  E-value: 1.53e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 640932300  62 LAALLTQESGFNPKA--SSPVGAQGIAQFMPSTWETHGidgnGDGKRDVWDPEDAIPSSAKY 121
Cdd:cd00442    2 LAAIIGQESGGNKPAnaGSGSGAAGLFQFMPGTWKAYG----KNSSSDLNDPEASIEAAAKY 59
 
Name Accession Description Interval E-value
NlpC COG0791
Cell wall-associated hydrolase, NlpC_P60 family [Cell wall/membrane/envelope biogenesis];
107-313 2.51e-43

Cell wall-associated hydrolase, NlpC_P60 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440554 [Multi-domain]  Cd Length: 218  Bit Score: 148.69  E-value: 2.51e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 107 DVWDPEDAIPSSAKYLCTIAEDVKDVPGNKQSNMLAAYNAGSGAVRKYGGIPPY----KETQGYVRAITSLANKNSGGGA 182
Cdd:COG0791   14 AAAALAAVAAAGALAAADAAVAAALVAAAAAVLAAAALLAGPAAAVAGAAAPAVgsagAAAAAAAAKAGSSAAKSAAGAS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 183 PATADQGVTALNAAQKMLGKPYSWGGgnaNGPSkgtccspkgrsgasitGFDCSGLTLYAYAKAGIALPRTAAQQYAASE 262
Cdd:COG0791   94 APPSSTAEAIVAAALSYLGTPYVWGG---TSPS----------------GFDCSGLVQYVYRQAGISLPRTSADQAAAGT 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 640932300 263 PIKHDQAKPGDLVFYGASASGIHHVGIYVGGGYMLDAPRPGTQVRFSPLDS 313
Cdd:COG0791  155 PVSRSELQPGDLVFFRTGGGGISHVGIYLGNGKFIHASSSGKGVRISSLDS 205
Slt35-like cd13399
Slt35-like lytic transglycosylase; Lytic transglycosylase similar to Escherichia coli lytic ...
 55-176 3.53e-42

Slt35-like lytic transglycosylase; Lytic transglycosylase similar to Escherichia coli lytic transglycosylase Slt35 and Pseudomonas aeruginosa Sltb1. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).


Pssm-ID: 381602 [Multi-domain]  Cd Length: 108  Bit Score: 142.06  E-value: 3.53e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  55 PEVSPNLLAALLTQESGFNPKA-SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVWDPEDAIPSSAKYLCTIAEDVKDVP 133
Cdd:cd13399    1 YGVPPGILAAILGVESGFGPNAgGSPAGAQGIAQFMPSTWKAYGVDGNGDGKADPFNPEDAIASAANYLCRHGWDLNAFL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 640932300 134 GNKQSNMLAAYNAGSGavrkyggippyketqGYVRAITSLANK 176
Cdd:cd13399   81 GEDNFLALAAYNAGPG---------------AYANAVLELAAT 108
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 31-175 6.20e-32

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 119.71  E-value: 6.20e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  31 AGTALSLAVPAQYQSMIEDAGNTcPEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGID-GNGDGKRDVW 109
Cdd:COG0741   91 ALAALLLRRPLPYLPLIEEAAKK-YGVDPALVLALIRQESAFNPNAVSPAGARGLMQLMPATARRLGLKlGLGPSPDDLF 169

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640932300 110 DPEDAIPSSAKYLctiaEDVKDVPGNKQSNMLAAYNAGSGAVRKY--------GGIPPYKETQGYVRAITSLAN 175
Cdd:COG0741  170 DPETNIRAGAAYL----RELLDRFDGDLVLALAAYNAGPGRVRRWlrrngdrdGEIIPYAETRNYVKKVLANYA 239
LT-like cd00254
lytic transglycosylase(LT)-like domain; Members include the soluble and insoluble ...
 59-175 2.66e-31

lytic transglycosylase(LT)-like domain; Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.


Pssm-ID: 381594 [Multi-domain]  Cd Length: 111  Bit Score: 113.85  E-value: 2.66e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  59 PNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGidgnGDGKRDVWDPEDAIPSSAKYLCTIAedvkDVPGNKQS 138
Cdd:cd00254    1 PALVLAVIRVESGFNPRAVSPAGARGLMQLMPGTARDLG----RRGVDDLFDPEENIRAGARYLRELL----DRFGGDLE 72

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 640932300 139 NMLAAYNAGSGAVRKYGG--IPPYKETQGYVRAITSLAN 175
Cdd:cd00254   73 LALAAYNAGPGAVDRWGGgeVPPYKETRNYVQRVLAYYQ 111
NLPC_P60 pfam00877
NlpC/P60 family; The function of this domain is unknown. It is found in several lipoproteins.
 201-313 7.23e-30

NlpC/P60 family; The function of this domain is unknown. It is found in several lipoproteins.


Pssm-ID: 395705 [Multi-domain]  Cd Length: 105  Bit Score: 109.68  E-value: 7.23e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  201 GKPYSWGGGnangpskgtccspkgrsgaSITGFDCSGLTLYAYAKAGIALPRTAAQQYAA-SEPIKHDQAKPGDLVFYGa 279
Cdd:pfam00877   1 GVPYRWGGG-------------------SPSGFDCSGLVRYAFAKVGIELPRSSGQQYNAgKKTIPKSEPQRGDLVFFG- 60

                          90       100       110
                  ....*....|....*....|....*....|....
gi 640932300  280 SASGIHHVGIYVGGGYMLDAPrPGTQVRFSPLDS 313
Cdd:pfam00877  61 TGKGISHVGIYLGNGQMLHAS-TGGGVSISSLNG 93
PRK13914 PRK13914
invasion associated endopeptidase;
171-305 6.01e-29

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 116.05  E-value: 6.01e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 171 TSLANKNSGGGAPATADQGVTALNAAQKMLGKPYSWGGgnaNGPskgtccspkgrsgasiTGFDCSGLTLYAYAKAGIAL 250
Cdd:PRK13914 348 NSNTNANQGSSNNNSNSSASAIIAEAQKHLGKAYSWGG---NGP----------------TTFDCSGYTKYVFAKAGISL 408

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 640932300 251 PRTAAQQYAASEPIKHDQAKPGDLVFYGaSASGIHHVGIYVGGGYMLDAPRPGTQ 305
Cdd:PRK13914 409 PRTSGAQYASTTRISESQAKPGDLVFFD-YGSGISHVGIYVGNGQMINAQDNGVK 462
NlpC_inact_RipD NF033743
NlpC/P60 family peptidoglycan-binding protein RipD; RipD proteins, such as founding member ...
 201-310 4.74e-27

NlpC/P60 family peptidoglycan-binding protein RipD; RipD proteins, such as founding member Rv1566c from Mycobacterium tuberculosis, is a catalytically inactive paralog of the peptidoglycan endopeptidases RipA and RipB. A catalytically important Cys and His pair is replaced by Ala-83 and Ser-132.


Pssm-ID: 468164 [Multi-domain]  Cd Length: 177  Bit Score: 104.77  E-value: 4.74e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300 201 GKPYSWGGGNANGPSKGTCCSPK---------GRSGASITGFDCSGLTLYAYAKAGIALPRTAAQQYAASEPIKHDQAKP 271
Cdd:NF033743  48 GVPFSYGGGNANGPTRGTGAGPAalnlpgaapGAPGPNVVGFDASGLMVYAFAGAGVKLPRSSGEQYKVGQKVLPAQALP 127

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 640932300 272 GDLVFYGasASGIHHVGIYVGGGYMLDAPRPGTQVrfSP 310
Cdd:NF033743 128 GDLIFYG--PEGTQSVALFLGNGQMLEATDPGVTV--SP 162
Slt70-like cd13401
70kDa soluble lytic transglycosylase (Slt70) and similar proteins; Catalytic domain of the ...
 40-175 1.31e-22

70kDa soluble lytic transglycosylase (Slt70) and similar proteins; Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.


Pssm-ID: 381604 [Multi-domain]  Cd Length: 152  Bit Score: 91.77  E-value: 1.31e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  40 PAQYQSMIEDAGNTcPEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPST--WETHGIDGNGDGKRDVWDPEDAIPS 117
Cdd:cd13401    3 PLPYRDLVERAAKK-NGLDPALVYAIIRQESAFDPDAVSPAGALGLMQLMPATakDVAKKLGLPYYSPRDLFDPEYNIRL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 640932300 118 SAKYLctiaEDVKDvpGNKQSNML--AAYNAGSGAVRK----YGGIP--------PYKETQGYVRAItsLAN 175
Cdd:cd13401   82 GSAYL----AELLD--RFDGNPVLalAAYNAGPGRVRRwlkrRGDLDpdlwietiPFSETRNYVKRV--LEN 145
MltF COG4623
Membrane-bound lytic murein transglycosylase MltF [Cell wall/membrane/envelope biogenesis, ...
 61-170 1.44e-21

Membrane-bound lytic murein transglycosylase MltF [Cell wall/membrane/envelope biogenesis, Signal transduction mechanisms];


Pssm-ID: 443662 [Multi-domain]  Cd Length: 421  Bit Score: 94.36  E-value: 1.44e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  61 LLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGIDgngdgkrDVWDPEDAIPSSAKYLCTIAEDVKDVPGNKQSN- 139
Cdd:COG4623  281 LLAALAYQESHWNPRARSPTGARGLMQLMPATAKELGVD-------DRLDPEQSIRAGAKYLRWLYDRFPEAIDEPDRWw 353

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 640932300 140 -MLAAYNAGSGAVR-------KYGG-----------IPPY--------KETQGYVRAI 170
Cdd:COG4623  354 fALAAYNAGPGHVQdarrlakKQGLdpdrwfdveksQPKYydtgyargRETVNYVPNI 411
SLT pfam01464
Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found ...
 55-164 1.66e-21

Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.


Pssm-ID: 396169 [Multi-domain]  Cd Length: 114  Bit Score: 87.75  E-value: 1.66e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300   55 PEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGIDGNgDGKRDVWDPEDAIPSSAKYLctiaEDVKDVPG 134
Cdd:pfam01464   8 YGVDPSLLLAIAQQESGFNPKAVSKSGAVGLMQIMPSTAKRLGLRVN-PGVDDLFDPEKNIKAGTKYL----KELYKQYG 82

                          90       100       110
                  ....*....|....*....|....*....|
gi 640932300  135 NKQSNMLAAYNAGSGAVRKYGGIPPYKETQ 164
Cdd:pfam01464  83 GDLWLALAAYNAGPGRVRKWIKNAGAKDKK 112
LT_Slt70-like cd16896
uncharacterized lytic transglycosylase subfamily with similarity to Slt70; Uncharacterized ...
 57-168 4.19e-19

uncharacterized lytic transglycosylase subfamily with similarity to Slt70; Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.


Pssm-ID: 381617 [Multi-domain]  Cd Length: 146  Bit Score: 82.17  E-value: 4.19e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  57 VSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPST--WETHGIDGNGDGKRDVWDPEDAIPSSAKYLctiaEDVKDVPG 134
Cdd:cd16896   17 VDPLLVAAVIKVESNFNPNAVSSKGAIGLMQIMPETaeWIAEKLGLEDFSEDDLYDPETNIRLGTWYL----SYLLKEFD 92

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 640932300 135 NKQSNMLAAYNAGSGAVRKY---GGIP---------PYKETQGYVR 168
Cdd:cd16896   93 GNLVLALAAYNAGPGNVDKWlkdGGWSgdgktldqiPFPETRHYVK 138
MLTF-like cd13403
membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins; This subfamily ...
 61-158 6.27e-19

membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins; This subfamily includes membrane-bound lytic murein transglycosylase F (MltF, murein lyase F) that degrades murein glycan strands. It is responsible for catalyzing the release of 1,6-anhydromuropeptides from peptidoglycan. Lytic transglycosylase catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do goose-type lysozymes. However, in addition, it also makes a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.


Pssm-ID: 381606 [Multi-domain]  Cd Length: 161  Bit Score: 82.20  E-value: 6.27e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  61 LLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGIDgngdgkrDVWDPEDAIPSSAKYLCTIAEDVKDV--PGNKQS 138
Cdd:cd13403   14 LLAAQAYQESRFNPNARSPAGARGLMQLMPSTARELGVN-------DRLDPEQNIHAGAKYLRYLRDRFPPDidEPDRLK 86

                         90       100
                 ....*....|....*....|....*..
gi 640932300 139 NMLAAYNAGSGAVR-------KYGGIP 158
Cdd:cd13403   87 FALAAYNAGPGHVRdarrlakKYGLNP 113
SLT_2 pfam13406
Transglycosylase SLT domain; This family is related to the SLT domain pfam01464.
 61-122 3.66e-16

Transglycosylase SLT domain; This family is related to the SLT domain pfam01464.


Pssm-ID: 404311 [Multi-domain]  Cd Length: 292  Bit Score: 77.59  E-value: 3.66e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640932300   61 LLAAL-LTQESGFNPKA--SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVWD-PEDAIPSSAKYL 122
Cdd:pfam13406 131 LIAALkILDRGDLDPEQlkGSWAGAMGQTQFMPSSYLAYAVDFDGDGRRDLWNsPPDALASVANYL 196
MltB COG2951
Membrane-bound lytic murein transglycosylase B [Cell wall/membrane/envelope biogenesis];
61-122 2.82e-15

Membrane-bound lytic murein transglycosylase B [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442193 [Multi-domain]  Cd Length: 326  Bit Score: 75.20  E-value: 2.82e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640932300  61 LLAAL-LTQESGFNPKA--SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVW-DPEDAIPSSAKYL 122
Cdd:COG2951  157 LIAALkILQRGDIDPDQmkGSWAGAMGQTQFMPSSYLRYAVDFDGDGRRDLWnSPPDALASTANYL 222
MltD-like cd16894
Membrane-bound lytic murein transglycosylase D and similar proteins; Lytic transglycosylases ...
 59-174 1.15e-14

Membrane-bound lytic murein transglycosylase D and similar proteins; Lytic transglycosylases (LT) catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc). Membrane-bound lytic murein transglycosylase D protein (MltD) family members may have one or more small LysM domains, which may contribute to peptidoglycan binding. Unlike the similar "goose-type" lysozymes, LTs also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).


Pssm-ID: 381615 [Multi-domain]  Cd Length: 129  Bit Score: 69.47  E-value: 1.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  59 PNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHG--IDGNGDGKRDVWDPEDAipsSAKYLctiaedvKDVpgNK 136
Cdd:cd16894    7 PEELKYLALVESGFNPDAVSSAGAAGLWQFMPATAREYGlrVDSWVDERRDPEKSTRA---AARYL-------KDL--YK 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 640932300 137 QSN----MLAAYNAGSG----AVRKYGGIPPY--------KETQGYVRAITSLA 174
Cdd:cd16894   75 RFGdwllALAAYNAGEGrvrrAIKRAGTDKWEdyyrlylpAETRRYVPKFLAAK 128
PRK11619 PRK11619
lytic murein transglycosylase; Provisional
 37-168 4.52e-12

lytic murein transglycosylase; Provisional


Pssm-ID: 183236 [Multi-domain]  Cd Length: 644  Bit Score: 66.62  E-value: 4.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  37 LAVPAQYQSMIEDAGntcpeVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTwETH-----GIDGNGDGKRdVWDP 111
Cdd:PRK11619 477 LAWNDEFRRYTSGKG-----IPQSYAMAIARQESAWNPKARSPVGASGLMQIMPGT-ATHtvkmfSIPGYSSSSQ-LLDP 549

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 640932300 112 EDAIPSSAKYLctiaEDVKDVPGNKQSNMLAAYNAGSGAVRKYGG--------------IpPYKETQGYVR 168
Cdd:PRK11619 550 ETNINIGTSYL----EYVYQQFGNNRILASAAYNAGPGRVRTWLGnsagridavafvesI-PFSETRGYVK 615
MltB_2 TIGR02283
lytic murein transglycosylase; Members of this family are closely related to the MltB family ...
 61-122 6.39e-12

lytic murein transglycosylase; Members of this family are closely related to the MltB family lytic murein transglycosylases described by TIGR02282 and are likewise all proteobacterial, although that family and this one form clearly distinct clades. Several species have one member of each family. Many members of this family (unlike the MltB family) contain an additional C-terminal domain, a putative peptidoglycan binding domain (pfam01471), not included in region described by this model. Many sequences appear to contain N-terminal lipoprotein attachment sites, as does E. coli MltB in TIGR02282. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 274067 [Multi-domain]  Cd Length: 300  Bit Score: 65.09  E-value: 6.39e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640932300   61 LLAALLTQESGFNPKA---SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVW-DPEDAIPSSAKYL 122
Cdd:TIGR02283 132 LIAALKILQRGDLTRAamkGSWAGAMGQTQFLPSSYLNYAVDFDGDGRRDIWnSVPDALASTANYL 197
PRK10760 PRK10760
murein hydrolase B; Provisional
 65-121 1.49e-10

murein hydrolase B; Provisional


Pssm-ID: 236754 [Multi-domain]  Cd Length: 359  Bit Score: 61.68  E-value: 1.49e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 640932300  65 LLTQESGFNPKA--SSPVGAQGIAQFMPSTWETHGIDGNGDGKRDVWDPEDAIPSSAKY 121
Cdd:PRK10760 199 LMARDEGDDPLNlrGSFAGAMGYGQFMPSSFKQYAVDFNGDGHINLWDPVDAIGSVANY 257
Lyz-like cd00442
lysozyme-like domains; This family contains several members, including soluble lytic ...
 62-121 1.53e-09

lysozyme-like domains; This family contains several members, including soluble lytic transglycosylases (SLT), goose egg-white lysozymes (GEWL), hen egg-white lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, chitosanases, and pesticin. Typical members are involved in the hydrolysis of beta-1,4- linked polysaccharides.


Pssm-ID: 381596 [Multi-domain]  Cd Length: 59  Bit Score: 53.18  E-value: 1.53e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 640932300  62 LAALLTQESGFNPKA--SSPVGAQGIAQFMPSTWETHGidgnGDGKRDVWDPEDAIPSSAKY 121
Cdd:cd00442    2 LAAIIGQESGGNKPAnaGSGSGAAGLFQFMPGTWKAYG----KNSSSDLNDPEASIEAAAKY 59
spr PRK10838
bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase;
227-292 7.96e-09

bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase;


Pssm-ID: 236773 [Multi-domain]  Cd Length: 190  Bit Score: 54.77  E-value: 7.96e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 640932300 227 GASITGFDCSGLTLYAYAKA-GIALPRTAAQQYAASEPIKHDQAKPGDLVFYGASASGiHHVGIYVG 292
Cdd:PRK10838  86 GSTKKGIDCSAFVQRTFREQfGLELPRSTYEQQEMGKSVSRSKLRTGDLVLFRAGSTG-RHVGIYIG 151
LT_MltC_MltE cd16893
membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins; MltC and ...
 57-154 1.49e-08

membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins; MltC and MltE are periplasmic, outer membrane attached lytic transglycosylases (LTs), which cleave beta-1,4-glycosidic bonds joining N-acetylmuramic acid and N-acetylglucosamine in the cell wall peptidoglycan, yielding 1,6-anhydromuropeptides. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda


Pssm-ID: 381614 [Multi-domain]  Cd Length: 162  Bit Score: 53.33  E-value: 1.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  57 VSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPStweTHGID-----GNGDG---KRDVWDPEDAIPSSAKYLcTIAED 128
Cdd:cd16893   12 VDPALILAIIETESSFNPYAVSHSPAYGLMQIVPS---TAGRDvyrllGGKGGlpsKSYLFDPENNIDIGTAYL-HILQN 87

                         90       100       110
                 ....*....|....*....|....*....|.
gi 640932300 129 -----VKDvPGNKQSNMLAAYNAGSGAVRKY 154
Cdd:cd16893   88 rylkgIKN-PKSREYCAIAAYNGGAGNVLRT 117
PRK10859 PRK10859
membrane-bound lytic murein transglycosylase MltF;
42-152 4.77e-08

membrane-bound lytic murein transglycosylase MltF;


Pssm-ID: 236778 [Multi-domain]  Cd Length: 482  Bit Score: 54.11  E-value: 4.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  42 QYQSMIEDAGNtcpEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGIDgngdgkrDVWDPEDAIPSSAKY 121
Cdd:PRK10859 289 KYQPLFEKYAG---ELDWRLLAAIAYQESHWNPQATSPTGVRGLMMLTRNTAQSMGVT-------DRLDPEQSIRGGARY 358

                         90       100       110
                 ....*....|....*....|....*....|...
gi 640932300 122 LCTIAEDVKD-VPGNKQSNM-LAAYNAGSGAVR 152
Cdd:PRK10859 359 LQDLMERLPEsIPEPERIWFaLAAYNIGYGHML 391
PHA00368 PHA00368
internal virion protein D
 39-149 3.03e-07

internal virion protein D


Pssm-ID: 222785 [Multi-domain]  Cd Length: 1315  Bit Score: 52.09  E-value: 3.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300   39 VPAQYQSMIEDAGNTcPEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPSTWETHGIDGNGDGKrdvWDPEDAIPSS 118
Cdd:PHA00368    7 KPSEYDGLFQKAADA-HGVSYDLLRKVGWDESRFNPTAKSPTGPKGLMQFTKATAKALGLIVDDDDR---LDPELAIDAG 82

                          90       100       110
                  ....*....|....*....|....*....|.
gi 640932300  119 AKYLctiAEDVKDVPGNKQSNMLaAYNAGSG 149
Cdd:PHA00368   83 ARYL---ADLVGKYDGDELKAAL-AYNQGEG 109
mltD PRK10783
membrane-bound lytic murein transglycosylase D; Provisional
 69-178 8.07e-06

membrane-bound lytic murein transglycosylase D; Provisional


Pssm-ID: 182727 [Multi-domain]  Cd Length: 456  Bit Score: 47.04  E-value: 8.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  69 ESGFNPKASSPVGAQGIAQFMPSTWETHGIDGNG--DGKRDVWDPEDAIPSSAKYLctiaedvkdvpgNKQSN-----ML 141
Cdd:PRK10783 128 ESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRwyDARRDVVASTTAALDMMQRL------------NKMFDgdwllTV 195

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 640932300 142 AAYNAGSGAVRK-------------YGGIPPYKETQGYVRAITSLAN--KNS 178
Cdd:PRK10783 196 AAYNSGEGRVMKaikankakgkptdFWSLSLPRETKIYVPKMLALSDilKNS 247
mltC PRK11671
membrane-bound lytic murein transglycosylase MltC;
57-151 2.35e-05

membrane-bound lytic murein transglycosylase MltC;


Pssm-ID: 183271 [Multi-domain]  Cd Length: 359  Bit Score: 45.43  E-value: 2.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  57 VSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPST-----WETHGIDGNGDgKRDVWDPEDAIPSSAKYLcTIAEDVK- 130
Cdd:PRK11671 205 VDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTagkdvFRMKGKSGQPS-RSYLFDPANNIDTGTAYL-AILQNVYl 282

                         90       100
                 ....*....|....*....|....
gi 640932300 131 ---DVPGNKQSNMLAAYNAGSGAV 151
Cdd:PRK11671 283 ggiTNPTSRRYAVITAYNGGAGSV 306
emtA PRK15470
membrane-bound lytic murein transglycosylase EmtA;
42-151 4.69e-04

membrane-bound lytic murein transglycosylase EmtA;


Pssm-ID: 185367 [Multi-domain]  Cd Length: 203  Bit Score: 40.72  E-value: 4.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640932300  42 QYQSMIEDAGNTCpEVSPNLLAALLTQESGFNPKASSPVGAQGIAQFMPST-----WETHGIDGNgDGKRDVWDPEDAIP 116
Cdd:PRK15470  38 QWMPISQKAGAAW-GVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTsgrdvYRRMGWSGE-PTTSELKNPERNIS 115

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 640932300 117 SSAKYLcTIAED-----VKDvPGNKQSNMLAAYNAGSGAV 151
Cdd:PRK15470 116 MGAAYL-NILETgplagIED-PKVLQYALVVSYANGAGAL 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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