NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|677652368|gb|KFR81917|]
View 

isochorismate synthase [Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000966]

Protein Classification

isochorismate synthase EntC( domain architecture ID 11487569)

isochorismate synthase EntC catalyzes the reversible conversion of chorismate to isochorismate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 1-391 0e+00

isochorismate synthase EntC; Provisional


:

Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 838.76  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368   1 MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPF 80
Cdd:PRK15016   1 MDTSLAEEVQQTMATLAPDRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  81 DTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQSLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV 160
Cdd:PRK15016  81 DTRQPSSLYIPESWQSFSRQEKQRSARRFTRSQSLNVVERQAIPEQTTFEAMVARAAALTATPQVDKVVLSRLIDITTDA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 161 AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH 240
Cdd:PRK15016 161 AIDSGALLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 241 EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELE 320
Cdd:PRK15016 241 EHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANAQENALTLACLLHPTPALSGFPHQAAKQVIAELE 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 677652368 321 PFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH 391
Cdd:PRK15016 321 PFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 391
 
Name Accession Description Interval E-value
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 1-391 0e+00

isochorismate synthase EntC; Provisional


Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 838.76  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368   1 MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPF 80
Cdd:PRK15016   1 MDTSLAEEVQQTMATLAPDRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  81 DTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQSLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV 160
Cdd:PRK15016  81 DTRQPSSLYIPESWQSFSRQEKQRSARRFTRSQSLNVVERQAIPEQTTFEAMVARAAALTATPQVDKVVLSRLIDITTDA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 161 AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH 240
Cdd:PRK15016 161 AIDSGALLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 241 EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELE 320
Cdd:PRK15016 241 EHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANAQENALTLACLLHPTPALSGFPHQAAKQVIAELE 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 677652368 321 PFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH 391
Cdd:PRK15016 321 PFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 391
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 19-391 2.63e-146

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 418.79  E-value: 2.63e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  19 DRFFFMSPYRSFT--TSGCFARYTEPavaGDSPDSPFQQKLRQQFAEAKSQGiANPILVGAIPFDTRQP---SSLFIPma 93
Cdd:COG1169    1 PRFYWASPDRGEGlaGLGEAARFEAP---GPDRFAALAAAWQALLADAALAG-TGPRAFGGFAFDPDSPapaARLVLP-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  94 wqsfsrqqkqrtaryftdhQSLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVA 173
Cdd:COG1169   75 -------------------RLLLRRSRRGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEPIDPRALLARLRR 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 174 QNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQIL 253
Cdd:COG1169  136 RNPDCYTFAVELGAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREAL 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 254 RDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGW 333
Cdd:COG1169  216 APLCSSLDVPEEPELLRLRNVQHLATPITGTLDPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVGW 295

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 677652368 334 CDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH 391
Cdd:COG1169  296 VDADGDGEFAVAIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTMLRALGLE 353
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 72-388 1.80e-91

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 278.87  E-value: 1.80e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368   72 PILVGAIPFDTRQPS--------SLFIP--MAWQS---------FSRQQKQRTARYFTDHQ---------------SLTV 117
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAaweefgegYFVLPevLVESDgggtlltctIVAEPELNEADLLLYAKfavssgirplralpeQMTT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  118 TARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPE 197
Cdd:TIGR00543  81 LTTGEDPDKAAWRTAVEEALENIRQGPLDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEPPQGGVFLGATPE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  198 LLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHL 277
Cdd:TIGR00543 161 RLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPELLKLANVQHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  278 GTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVR 357
Cdd:TIGR00543 241 YTPISARLKDGDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGEGNGEFAVGIRSALVEDGQVR 320

                         330       340       350
                  ....*....|....*....|....*....|.
gi 677652368  358 LFAGAGIVPASSPVGEWRETGVKLSTMLNVF 388
Cdd:TIGR00543 321 LYAGAGIVADSDPESEWEETELKLQTMLRAL 351
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 127-380 2.67e-90

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 272.50  E-value: 2.67e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  127 DAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYNFHVPLaDGGVLLGASPELLLRKEGER 206
Cdd:pfam00425   1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYFRT-GDFTFLGASPERLLSVDGGR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  207 FSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQILR--DRSTELQLPSSPQLITTPTLWHLGTPFEGK 284
Cdd:pfam00425  80 IITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGrvCVPGSVKVPELPEVERYGTVQHLVSTISGR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  285 ANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGI 364
Cdd:pfam00425 160 LKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGI 239

                         250
                  ....*....|....*.
gi 677652368  365 VPASSPVGEWRETGVK 380
Cdd:pfam00425 240 VADSDPEAEWEETEAK 255
 
Name Accession Description Interval E-value
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 1-391 0e+00

isochorismate synthase EntC; Provisional


Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 838.76  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368   1 MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPF 80
Cdd:PRK15016   1 MDTSLAEEVQQTMATLAPDRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  81 DTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQSLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV 160
Cdd:PRK15016  81 DTRQPSSLYIPESWQSFSRQEKQRSARRFTRSQSLNVVERQAIPEQTTFEAMVARAAALTATPQVDKVVLSRLIDITTDA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 161 AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH 240
Cdd:PRK15016 161 AIDSGALLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 241 EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELE 320
Cdd:PRK15016 241 EHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANAQENALTLACLLHPTPALSGFPHQAAKQVIAELE 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 677652368 321 PFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH 391
Cdd:PRK15016 321 PFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 391
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 19-391 2.63e-146

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 418.79  E-value: 2.63e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  19 DRFFFMSPYRSFT--TSGCFARYTEPavaGDSPDSPFQQKLRQQFAEAKSQGiANPILVGAIPFDTRQP---SSLFIPma 93
Cdd:COG1169    1 PRFYWASPDRGEGlaGLGEAARFEAP---GPDRFAALAAAWQALLADAALAG-TGPRAFGGFAFDPDSPapaARLVLP-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  94 wqsfsrqqkqrtaryftdhQSLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVA 173
Cdd:COG1169   75 -------------------RLLLRRSRRGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEPIDPRALLARLRR 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 174 QNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQIL 253
Cdd:COG1169  136 RNPDCYTFAVELGAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREAL 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 254 RDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGW 333
Cdd:COG1169  216 APLCSSLDVPEEPELLRLRNVQHLATPITGTLDPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVGW 295

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 677652368 334 CDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH 391
Cdd:COG1169  296 VDADGDGEFAVAIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTMLRALGLE 353
PRK06923 PRK06923
isochorismate synthase DhbC; Validated
 17-390 5.44e-105

isochorismate synthase DhbC; Validated


Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 315.13  E-value: 5.44e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  17 APDRFFFMSPYRSFTTSGCFARYTEpavagdSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPFDTRQPSSLFIPMAWQS 96
Cdd:PRK06923  20 TESSFFFASPTRTILAEGEFTTVKH------HEIESFPERVQAVLRNAKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRI 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  97 FSRQQKQRTARyFTDHQSLTVTARKaIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNP 176
Cdd:PRK06923  94 SERLQLDTTNH-LEINRNLTFEMTP-VPDPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVKSSEKIDKQKLLRELAEHNK 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 177 VSYNFHVPLADG-----GVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQ 251
Cdd:PRK06923 172 HGYTFAVNLPKDenensKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVEAVAA 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 252 ILRDRSTELQLPSSPQLITTPTLWHLGTPFEGK-ANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGI 330
Cdd:PRK06923 252 ALRPYCHTLHVPEKPSVIHTEAMWHLSTEVKGElKDPNTSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREFFTGM 331

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 331 VGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGL 390
Cdd:PRK06923 332 LGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKAMGL 391
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 72-388 1.80e-91

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 278.87  E-value: 1.80e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368   72 PILVGAIPFDTRQPS--------SLFIP--MAWQS---------FSRQQKQRTARYFTDHQ---------------SLTV 117
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAaweefgegYFVLPevLVESDgggtlltctIVAEPELNEADLLLYAKfavssgirplralpeQMTT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  118 TARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPE 197
Cdd:TIGR00543  81 LTTGEDPDKAAWRTAVEEALENIRQGPLDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEPPQGGVFLGATPE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  198 LLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHL 277
Cdd:TIGR00543 161 RLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPELLKLANVQHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  278 GTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVR 357
Cdd:TIGR00543 241 YTPISARLKDGDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGEGNGEFAVGIRSALVEDGQVR 320

                         330       340       350
                  ....*....|....*....|....*....|.
gi 677652368  358 LFAGAGIVPASSPVGEWRETGVKLSTMLNVF 388
Cdd:TIGR00543 321 LYAGAGIVADSDPESEWEETELKLQTMLRAL 351
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 127-380 2.67e-90

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 272.50  E-value: 2.67e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  127 DAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYNFHVPLaDGGVLLGASPELLLRKEGER 206
Cdd:pfam00425   1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYFRT-GDFTFLGASPERLLSVDGGR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  207 FSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQILR--DRSTELQLPSSPQLITTPTLWHLGTPFEGK 284
Cdd:pfam00425  80 IITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGrvCVPGSVKVPELPEVERYGTVQHLVSTISGR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  285 ANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGI 364
Cdd:pfam00425 160 LKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGI 239

                         250
                  ....*....|....*.
gi 677652368  365 VPASSPVGEWRETGVK 380
Cdd:pfam00425 240 VADSDPEAEWEETEAK 255
PRK07054 PRK07054
isochorismate synthase;
49-384 4.06e-57

isochorismate synthase;


Pssm-ID: 235920 [Multi-domain]  Cd Length: 475  Bit Score: 193.83  E-value: 4.06e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  49 PDSPFQQ---KLRQQFAEAKSQGIANPILVGAIPFDTRQPSSlfipMAWQSFS-----------RQQKQRT--------- 105
Cdd:PRK07054  78 GDQRFARleaRWRALVADAVVAGPQPPRLVGGFRFDPRGPRS----AHWQAFAdasltlakllvVREGEAYwavcqhlva 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 106 --------ARYFTDH-QSLTVTARKAIPEQDAF-----------EAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSG 165
Cdd:PRK07054 154 ahddpaalAGACCARiERLARPAPAADDDAPRLlrasalqarewQHEVRRAVDAIRGGAFGKVVLARDVLQQYARPVAIG 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 166 ALLERLVAQNPVSYNFHVPlADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELV 245
Cdd:PRK07054 234 PLLRRLRLRDPHAHLFAFR-RGNACFLGATPERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALMASAKDRLEHALV 312

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 246 TQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRE 325
Cdd:PRK07054 313 VDAIRAALAPLSRALDIPDQPSLHRLPRLQHLSTPIRATLAPDATLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRG 392

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 677652368 326 LFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTM 384
Cdd:PRK07054 393 WYAAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVADSEPASEYRETCLKLSGM 451
PRK15012 PRK15012
menaquinone-specific isochorismate synthase; Provisional
 54-376 1.04e-39

menaquinone-specific isochorismate synthase; Provisional


Pssm-ID: 184974 [Multi-domain]  Cd Length: 431  Bit Score: 146.53  E-value: 1.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  54 QQKLRQQFAEAKSQgianpiLVGAIPFDTRQpSSLFIP---------MA------WQSFSRQQKQRTARYF--------- 109
Cdd:PRK15012  80 QRFLRQHPEHADLR------IWGLNAFDPSQ-GNLLLPrlewrrcggKAtlrltlFSESSLQHDAIQAKEFlatlvsikp 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 110 TDHQSLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYNFHVPLADGG 189
Cdd:PRK15012 153 LPGLHLTTTREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDAEN 232

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 190 VLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQILRDRSTELQ-LPssPQL 268
Cdd:PRK15012 233 AFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDvLP--PQV 310

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 269 ITTPTLWHLGTPFEGKANAGENALTLAcLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEgNGEWVVTIRC 348
Cdd:PRK15012 311 LRLRKVQHLRRCIWTSLNKADDVICLH-QLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQ-QSEFCVSLRS 388

                        330       340
                 ....*....|....*....|....*...
gi 677652368 349 AKLHGNQVRLFAGAGIVPASSPVGEWRE 376
Cdd:PRK15012 389 AKVSGNVVRLYAGAGIVRGSDPEQEWQE 416
PLN02786 PLN02786
isochorismate synthase
 115-382 7.32e-37

isochorismate synthase


Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 140.30  E-value: 7.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 115 LTVTARKAIPEQDAFEAMVARAAML--TATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYNFHVPLADGGVLL 192
Cdd:PLN02786 248 VSVLSKNHVPSKGAWHLAVNKALQIikRKSSPLKKVVLARSSRIITDTDIDPIAWLACLQVEGQNAYQFCLQPPDAPAFI 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 193 GASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVTQAMKQILRDRSTELQLPSSPQLITTP 272
Cdd:PLN02786 328 GNTPEQLFHRKGLGVCSEALAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICDRVVVEPHKAIRKLA 407

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 273 TLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNgEWVVTIRCAKLH 352
Cdd:PLN02786 408 RVQHLYAQLAGRLRSEDDEFDILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFGGGES-EFAVGIRSALVE 486

                        250       260       270
                 ....*....|....*....|....*....|.
gi 677652368 353 -GNQVRLFAGAGIVPASSPVGEWRETGVKLS 382
Cdd:PLN02786 487 kGLGALIYAGTGIVEGSNPSSEWNELELKIS 517
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 21-390 7.75e-32

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 124.44  E-value: 7.75e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  21 FFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQkLRQQFAEAKSQGIAN--PI---LVGAIPFDT---------RQPS 86
Cdd:COG0147   45 FIGADPLATLTVRGGRVTIEGGGEVEPSEGDPLDA-LRALLARFRLPPLPGlpPFtggLVGYFGYDLvryferlpdLAPD 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368  87 SLFIPMAWQSFSRqqkqRTARYftDHQsltvTARKAIPEQDAFEAMVARA-AMLTATpDVDKVVLSRLIdiTTDVAVDSG 165
Cdd:COG0147  124 DLGLPDAALGLYD----RLLVF--DHL----KGTRSNFTREEYLAAVERAkEYIRAG-DIFQVVLSQRF--SAPFEGDPL 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 166 ALLERLVAQNPVSYNFHVPLaDGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEH--- 242
Cdd:COG0147  191 ALYRALRRINPSPYMFYLRF-GDFAIVGSSPERLVRVEDGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHlml 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 243 ------EL----------VTQAMKqILRdRStelqlpsspqlittpTLWHLGTPFEGKANAGENALTL--ACLlhptPA- 303
Cdd:COG0147  270 vdlarnDLgrvcepgsvkVPELMV-VER-YS---------------HVMHLVSTVTGRLRPGLDALDAlrATF----PAg 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 304 -LSGFPhqvaK----KLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETG 378
Cdd:COG0147  329 tLTGAP----KiramEIIDELEPTRRGVYGGAVGYLSFDGNMDLAIAIRTAVVKDGRAYVQAGAGIVADSDPEAEYQETL 404

                        410
                 ....*....|..
gi 677652368 379 VKLSTMLNVFGL 390
Cdd:COG0147  405 NKARALLRALEL 416
PRK13572 PRK13572
anthranilate synthase component I; Provisional
 127-390 3.91e-27

anthranilate synthase component I; Provisional


Pssm-ID: 237432 [Multi-domain]  Cd Length: 435  Bit Score: 111.75  E-value: 3.91e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 127 DAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVavDSGALLERLVAQNPVSYNFhvPLADGGVLLGASPELLLRKEGER 206
Cdd:PRK13572 173 EEFVEMVEKAKEYIYSGDVFQVVLSREYRLKTDL--SPFQLYRNLREINPSPYMF--LLEFDKDVVGASPETMASVENNI 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 207 FSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEH----ELVTQAMKQILRDRSTELQlpSSPQLITTPTLWHLGTPFE 282
Cdd:PRK13572 249 LKINPIAGTAPRGKTEEEDKKLAEALLSDEKERAEHvmlvDLARNDVRKVSKSGSVRLE--RFFDVVKYSHVQHIESEVV 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 283 GKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGnQVRLFAGA 362
Cdd:PRK13572 327 GELKEDSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMAEIDK-VCRVRAGA 405

                        250       260
                 ....*....|....*....|....*...
gi 677652368 363 GIVPASSPVGEWRETGVKLSTMLNVFGL 390
Cdd:PRK13572 406 GIVADSVPEKEFYETERKMAAVLKALGV 433
PRK13574 PRK13574
anthranilate synthase component I; Provisional
 147-381 8.16e-23

anthranilate synthase component I; Provisional


Pssm-ID: 184155 [Multi-domain]  Cd Length: 420  Bit Score: 99.12  E-value: 8.16e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 147 KVVLSRLIDITTDvavdsGALLE---RLVAQNPVSYNFHVPLADGGVLlGASPELLLRKEGERFSSLPLAGSARRQPDDV 223
Cdd:PRK13574 178 QVVLSRFYRYLFS-----GDPLRiyyNLRRINPSPYMFYLKFDERYLI-GSSPELLFRVQDNIVETYPIAGTRPRGSDQE 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 224 LDREAGNRLLASQKDRHEH-ELVTQAmkqilRDRSTELQLPSS---PQLITTPT---LWHLGTPFEGKANAGENALTLAC 296
Cdd:PRK13574 252 EDLKLELELMNSEKDKAEHlMLVDLA-----RNDLGKVCVPGTvrvPELMYVEKyshVQHIVSKVIGTLKKKYNALDVLK 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 297 LLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRE 376
Cdd:PRK13574 327 ATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKDLLRIQAGAGIVYDSNPESEYFE 406


                 ....*
gi 677652368 377 TGVKL 381
Cdd:PRK13574 407 TEHKL 411
PRK13571 PRK13571
anthranilate synthase component I; Provisional
 116-386 8.58e-20

anthranilate synthase component I; Provisional


Pssm-ID: 184152 [Multi-domain]  Cd Length: 506  Bit Score: 90.85  E-value: 8.58e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 116 TVTARKAIPEqdaFEAMVARAAMLTATPDVDKVVLSRLIDITTDV-AVDSGALLeRLVAQNPVSYNFHVPLADGGV---L 191
Cdd:PRK13571 222 EFRAQRTVEE---FGAAVEKLVEEIRAGEAFQVVPSQRFEMDTTAdPLDVYRVL-RVTNPSPYMYLLRVPNSDGGTdfsI 297

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 192 LGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEH----ELVTQAMKQILRDRSTELQLPSSPQ 267
Cdd:PRK13571 298 VGSSPEALVTVTDGRATTHPIAGTRWRGATPEEDALLEKELLADPKERAEHlmlvDLGRNDLGRVCRPGTVRVVDFSHIE 377

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 268 LITTptLWHLGTPFEGKANAGENAL--TLACLlhPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVT 345
Cdd:PRK13571 378 RYSH--VMHLVSTVTGELAEGRTALdaVTACF--PAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIA 453

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 677652368 346 IRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLN 386
Cdd:PRK13571 454 IRTALMRDGTAYVQAGGGVVADSDPDYEDNEARNKAAAVLR 494
PRK07508 PRK07508
aminodeoxychorismate synthase component I;
163-376 1.25e-19

aminodeoxychorismate synthase component I;


Pssm-ID: 236035 [Multi-domain]  Cd Length: 378  Bit Score: 89.30  E-value: 1.25e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 163 DSGALLERLVAQNPVSYNFHVPLaDGGVLLGASPELLLRKEGE-RFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHE 241
Cdd:PRK07508 146 DPLALFWALAARQPVGYGALVDL-GGPVILSRSPELFFRVDGEgWIETHPMKGTAPRGATPAEDARLRAALLNDEKNQAE 224

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 242 HELVTQamkqILRD---RSTE---LQLPSSPQLITTPTLWHLGTPFEGKANAGenaLTLACLLH---PTPALSGFPHQVA 312
Cdd:PRK07508 225 NRMIVD----LLRNdisRISEvgsLDVPELFDIETYPTVHQMVSRVRARLLPG---LGLADIFAalfPCGSITGAPKIRA 297

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 677652368 313 KKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKL-HGNQVRLFAGAGIVPASSPVGEWRE 376
Cdd:PRK07508 298 MEILRELEPGPRDLYCGAIGWIAPDGRMRFNVAIRTLSLfPGGRAVFNVGGGIVFDSTAEAEYEE 362
PRK09070 PRK09070
aminodeoxychorismate synthase component I;
144-390 1.51e-18

aminodeoxychorismate synthase component I;


Pssm-ID: 236371 [Multi-domain]  Cd Length: 447  Bit Score: 86.68  E-value: 1.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 144 DVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYNFHVPLADGGVLlGASPELLLRKEGERFSSLPLAGSARRQPDDV 223
Cdd:PRK09070 200 DVFQVNLSRAWQAQFANAVDPAALYARLRAANPAPFSGLFVAAGRAIV-SSSPERLVSVQGGVVQTRPIAGTRPRFAGDD 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 224 lDREAGNRLLASQKDRHEH----ELVTQAMKQILRDRSTELQlpsspQLITT---PTLWHLGTPFEGKANAGENALTLAC 296
Cdd:PRK09070 279 -DAALIRELVGHPKERAEHvmliDLERNDLGRICAPGSVEVD-----ELMTVesyAHVHHIVSNVRGRLRDGVTPGEVIR 352

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 297 LLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRE 376
Cdd:PRK09070 353 AVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGNQVRFRTGAGIVVDSDPERELDE 432

                        250
                 ....*....|....
gi 677652368 377 TGVKLSTMLNVFGL 390
Cdd:PRK09070 433 TRAKARGLLRALEQ 446
PRK05940 PRK05940
anthranilate synthase component I;
126-377 2.77e-15

anthranilate synthase component I;


Pssm-ID: 235651 [Multi-domain]  Cd Length: 463  Bit Score: 77.08  E-value: 2.77e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 126 QDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVavDSGALLERLVAQNP---VSYnFHVPLadgGVLLGASPELLLRK 202
Cdd:PRK05940 189 QQEYEAAVRQAKKYIQAGDIFQANLSLRFQTTTSA--DSWQIYRRLQQINPspfASY-WRTPW---GDVVSCSPERLVQL 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 203 EGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEH----ELVTQAMKQILRDRSTE----LQLPSSPQLIttptl 274
Cdd:PRK05940 263 QGNQAQTRPIAGTRPRGKTPAEDQQLAEELLSNIKERAEHimlvDLERNDLGRVCQWGSVEvdelLTIERYSHVI----- 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 275 wHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRC---AKL 351
Cdd:PRK05940 338 -HLVSNVVGTLQPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLDLNILIRTllyTPL 416

                        250       260
                 ....*....|....*....|....*...
gi 677652368 352 HGNQVRLFA--GAGIVPASSPVGEWRET 377
Cdd:PRK05940 417 SRGLSTIWGqvGAGIVADSDPEKEWLES 444
PRK06772 PRK06772
salicylate synthase;
127-384 4.68e-13

salicylate synthase;


Pssm-ID: 102546 [Multi-domain]  Cd Length: 434  Bit Score: 70.15  E-value: 4.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 127 DAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLvAQNPV-SYNFHvplADGGVLLGASPELLLRKEGE 205
Cdd:PRK06772 173 EAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQ-ANTPVrSFMFR---QEGREALGFSPELVMSVTGN 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 206 RFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHELVtqamkqiLRDRSTELQLPSSPQLITTPTLW---------H 276
Cdd:PRK06772 249 KVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILS-------VKEAIAELEAVCQPGSVVVEDLMsvrqrgsvqH 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 277 LGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDaEGNGEWVVTIRCAKLHGNQV 356
Cdd:PRK06772 322 LGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLD-DTRFDAALVLRSVFQDSQRC 400

                        250       260
                 ....*....|....*....|....*...
gi 677652368 357 RLFAGAGIVPASSPVGEWRETGVKLSTM 384
Cdd:PRK06772 401 WIQAGAGIIAQSTPERELTETREKLASI 428
pabB PRK15465
aminodeoxychorismate synthase component 1;
163-385 8.82e-13

aminodeoxychorismate synthase component 1;


Pssm-ID: 185362 [Multi-domain]  Cd Length: 453  Bit Score: 69.18  E-value: 8.82e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 163 DSGALLERLVAQNPVSYNFHVPLADGGVLlGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEH 242
Cdd:PRK15465 225 DEWQAFLQLNQANRAPFSAFLRLEQGAIL-SLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAEN 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 243 ELVTQAMkqilRDRSTELQLPSS---PQLITT---PTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLI 316
Cdd:PRK15465 304 LMIVDLM----RNDIGRVAVAGSvkvPELFVVepfPAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEII 379

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 677652368 317 AELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTML 385
Cdd:PRK15465 380 DELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNRIL 448
PRK06404 PRK06404
anthranilate synthase component I; Reviewed
 144-385 7.22e-12

anthranilate synthase component I; Reviewed


Pssm-ID: 102361 [Multi-domain]  Cd Length: 351  Bit Score: 66.05  E-value: 7.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 144 DVDKVVLSRlidiTTDVAVDSGALLERLVAQNPVSYNFHVPLADGGVLlGASPELLLRKEGERFSSLPLAGSArrqPDDV 223
Cdd:PRK06404 122 EVLQVVISR----EFEANIDFKEKLSEFINNDRSRYVFYYRFGKYRVV-GSSPENVFTVNGNIINVDPIAGTY---DDKI 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 224 LDreagNRLLASQKDRHEHELVTQAMKQILR---DRSTeLQLPSSPQLITTPTLWHLGTPFEGKAnAGENALTLACLLHP 300
Cdd:PRK06404 194 LS----NELLNSEKDKLEHRMLLDLARNDLSkfaDIGT-LNVDKVMKIEEFSSVKHLVSQVTAKF-SNASYRDILASMFP 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 301 TPALSGFPHQVAKKLIAELEPFDRELFGGIVGwCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVK 380
Cdd:PRK06404 268 AGTVSGSPKERAIEIINKYEETPRGPYGGAIG-IISKGYTDMALVIRTAYSHGNGFRVRAGAGIVKDSDPEDEVNEIYSK 346


                 ....*
gi 677652368 381 LSTML 385
Cdd:PRK06404 347 ARSVM 351
PRK13567 PRK13567
anthranilate synthase component I; Provisional
 167-387 8.71e-12

anthranilate synthase component I; Provisional


Pssm-ID: 184148 [Multi-domain]  Cd Length: 468  Bit Score: 66.32  E-value: 8.71e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 167 LLERLVAQNPVSYNFHVPLaDGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRHEHE-LV 245
Cdd:PRK13567 245 LYQNLKRQNPSPYMYYLNI-DQPYIVGSSPESFVSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRmLV 323

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 246 TQAMKQILRdrsteLQLPSSPQLITTPTL------WHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAEL 319
Cdd:PRK13567 324 DLGRNDIHR-----VSKIGTSKITKLMVIekyehvMHIVSEVTGKINQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQ 398

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 677652368 320 EPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNV 387
Cdd:PRK13567 399 YPHKRGVYSGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPEKELNETKLKAKSLLEV 466
PRK07912 PRK07912
salicylate synthase;
147-384 1.30e-11

salicylate synthase;


Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 65.58  E-value: 1.30e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 147 KVVLSRLIDITtdVAVDSGALLERLVAQNPVSYNFHVPLadGGV-LLGASPELLLRKEGER-FSSLPLAGSAR--RQPDD 222
Cdd:PRK07912 204 KVILSRCVEVP--FAVDFPATYRLGRRHNTPVRSFLLRL--GGIrALGYSPELVTAVRADGvVITEPLAGTRAfgRGAAI 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 223 vlDREAGNRLLASQKDRHEHEL-VTQAMKQIlrdrsTELQLPSSPQLITTPTL------WHLGTPFEGKANAGENALTLA 295
Cdd:PRK07912 280 --DRLARDDLESNSKEIVEHAIsVRSSLAEI-----TEIAEPGSAAVIDFMTVrergsvQHLGSTVRGRLDASSDRMDAL 352

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 296 CLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWR 375
Cdd:PRK07912 353 EALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFE 432


                 ....*....
gi 677652368 376 ETGVKLSTM 384
Cdd:PRK07912 433 ETCEKLSTL 441
PRK13566 PRK13566
anthranilate synthase component I;
166-385 3.67e-11

anthranilate synthase component I;


Pssm-ID: 237429 [Multi-domain]  Cd Length: 720  Bit Score: 64.94  E-value: 3.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 166 ALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDrhEHEL- 244
Cdd:PRK13566 281 EIFRRLKEINPSPYGFFINLGDGEYLVGASPEMFVRVEGRRVETCPISGTIKRGADAIGDAEQIRKLLNSKKD--ESELt 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 245 --------------VTQAMKQILRdRSTELQlpssPQLITTPTlwHLgtpfEGKANAGENALTlACLLHpTPA--LSGFP 308
Cdd:PRK13566 359 mctdvdrndksrvcEPGSVKVIGR-RQIEMY----SRLIHTVD--HV----EGRLRPGFDALD-AFLTH-AWAvtVTGAP 425

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 677652368 309 HQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGN--QVRlfAGAGIVPASSPVGEWRETGVKLSTML 385
Cdd:PRK13566 426 KLWAMQFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDGvaEVR--VGATLLFDSDPEAEEAETELKASALL 502
PRK05877 PRK05877
aminodeoxychorismate synthase component I; Provisional
 195-386 3.53e-09

aminodeoxychorismate synthase component I; Provisional


Pssm-ID: 235634 [Multi-domain]  Cd Length: 405  Bit Score: 58.18  E-value: 3.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 195 SPELLLRKEGERFSSLPLAGSARRQPDdvldreaGNRLLASQKDRHEH----ELVTQAMKQILRDRSteLQLPSSPQLIT 270
Cdd:PRK05877 207 SPELFLRRRGSVVTSSPIKGTLPLDAD-------PSALRASAKDVAENimivDLVRNDLGRVARTGT--VTVPELLVVRP 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 271 TPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAK 350
Cdd:PRK05877 278 APGVWHLVSTVSAQVPDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGCELNVAIRTVE 357

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 677652368 351 LHGN-QVRLFAGAGIVPASSPVGEWRETGVKLSTMLN 386
Cdd:PRK05877 358 FDADgNAVLGVGGGITADSDPDAEWQECLHKAAPIVG 394
PLN02445 PLN02445
anthranilate synthase component I
 170-377 4.98e-06

anthranilate synthase component I


Pssm-ID: 215244 [Multi-domain]  Cd Length: 523  Bit Score: 48.52  E-value: 4.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 170 RLVaqNPVSYNFHVPlADGGVLLGASPELLLRKEGERFSSLPLAGSARR----QPDDVLDREagnrLLASQKDRHEH--- 242
Cdd:PLN02445 279 RIV--NPSPYMIYLQ-ARGCILVASSPEILTRVKKNKIVNRPLAGTRRRgktpEEDKALEKD----LLADEKQCAEHiml 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 243 ---------------ELVTQAMKQILRdRSTELQLPSSpqlITTPTLWHLgTPFegkanageNALTLACllhPTPALSGF 307
Cdd:PLN02445 352 vdlgrndvgkvskagSVKVEKLMNIER-YSHVMHISST---VTGELLDHL-TSW--------DALRAAL---PVGTVSGA 415

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 677652368 308 PHQVAKKLIAELEPFDRELFGGIVG------------------------------WCDAEGNGEWVVTIRcaklhgnqvr 357
Cdd:PLN02445 416 PKVRAMELIDELEVTRRGPYSGGFGgvsftgdmdialalrtmvfptaarydtmysYKDTNSRREWVAHLQ---------- 485

                        250       260
                 ....*....|....*....|
gi 677652368 358 lfAGAGIVPASSPVGEWRET 377
Cdd:PLN02445 486 --AGAGIVADSDPEDEYREC 503
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH