|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
1-383 |
0e+00 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 659.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 1 MSDSFNSKSGKVRVMYVRSDDEGEKENKNKRPAdkdrrgdrrdgsgsrdqrekpkhprdvnpryaRENPSRDGDSNAksp 80
Cdd:PRK10864 1 MNDELKGKSGKVKVMYVRSDDDSDKRTHNPRTG--------------------------------KGGGRPSGKSRA--- 45
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 81 wgnkDRNERSGDKPRRPRGDDTGGYESPWKTVSRAPSD--SETPDHGGITGKSHIDPEQLRRQRQEETRVYGENACQALF 158
Cdd:PRK10864 46 ----DGGRRPARDDRNSQSRDRKWEDSPWRTVSRAPGDetPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALF 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 159 KNRSEVIVRAWFLQEVTPRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCFLIKKRQGMDVREYLKTAGEHDCVL 238
Cdd:PRK10864 122 QSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTDVQQWLAQAGAQDCVL 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 239 ALEDVGNPHNLGGIMRSCAHFGVKGVLVQDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTSSHKG 318
Cdd:PRK10864 202 ALEDVGNPHNLGGIMRSCAHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKG 281
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 684992527 319 TVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEWWRQNQA 383
Cdd:PRK10864 282 TPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEWWRQNKA 346
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
137-383 |
2.20e-71 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 224.30 E-value: 2.20e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 137 QLRRQRQEETR--VYGENACQALFKNRsEVIVRAWFLQEVTPRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCF 214
Cdd:COG0566 16 RDKKYREEEGLflAEGRHAVEEALKAG-REIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 215 LIKKRQGMDVREYLKTAGEHDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV-QDAALLESGAAVRTAEGGAEHVKAINA 293
Cdd:COG0566 95 VVRPPEYADLEDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILpKRRADPYNPKVVRASAGALFHVPVARV 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 294 DDFLSVLTEFRNAGYTIVTTSSHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGIL 373
Cdd:COG0566 175 TNLADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAIL 254
|
250
....*....|
gi 684992527 374 LSEWWRQNQA 383
Cdd:COG0566 255 LYEAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
236-377 |
5.37e-51 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 167.22 E-value: 5.37e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 236 CVLALEDVGNPHNLGGIMRSCAHFGVKGV-LVQDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTS 314
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGViLSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 684992527 315 SHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEW 377
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
237-374 |
2.35e-37 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 131.88 E-value: 2.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV--QDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTS 314
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILvePRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 315 sHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILL 374
Cdd:pfam00588 83 -LGGKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
147-380 |
1.73e-30 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 116.67 E-value: 1.73e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 147 RVYGENACQALFKNRSEVivrawFLQEVT--PRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCFLIKKRQGMDV 224
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQRV-----FILKGLesKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 225 REYLKTAGEHDC--VLALEDVGNPHNLGGIMRSCAHFGVKGVLV--QDAALLESGAaVRTAEGGAEHVKAINADDFLSVL 300
Cdd:TIGR00186 78 NDLYKTAKSKKQpfLLILDEITDPHNLGAILRTAEAFGVDGVILpkRRSAPLNSTV-VKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 301 TEFRNAGYTIVTTSSHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEWWRQ 380
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
148-218 |
1.58e-07 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 47.92 E-value: 1.58e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 684992527 148 VYGENACQALFKNRsEVIVRAWFLQEVTPRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCFLIKK 218
Cdd:smart00967 1 IEGRHAVEEALKSG-RRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
1-383 |
0e+00 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 659.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 1 MSDSFNSKSGKVRVMYVRSDDEGEKENKNKRPAdkdrrgdrrdgsgsrdqrekpkhprdvnpryaRENPSRDGDSNAksp 80
Cdd:PRK10864 1 MNDELKGKSGKVKVMYVRSDDDSDKRTHNPRTG--------------------------------KGGGRPSGKSRA--- 45
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 81 wgnkDRNERSGDKPRRPRGDDTGGYESPWKTVSRAPSD--SETPDHGGITGKSHIDPEQLRRQRQEETRVYGENACQALF 158
Cdd:PRK10864 46 ----DGGRRPARDDRNSQSRDRKWEDSPWRTVSRAPGDetPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALF 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 159 KNRSEVIVRAWFLQEVTPRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCFLIKKRQGMDVREYLKTAGEHDCVL 238
Cdd:PRK10864 122 QSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTDVQQWLAQAGAQDCVL 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 239 ALEDVGNPHNLGGIMRSCAHFGVKGVLVQDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTSSHKG 318
Cdd:PRK10864 202 ALEDVGNPHNLGGIMRSCAHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKG 281
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 684992527 319 TVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEWWRQNQA 383
Cdd:PRK10864 282 TPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEWWRQNKA 346
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
137-383 |
2.20e-71 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 224.30 E-value: 2.20e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 137 QLRRQRQEETR--VYGENACQALFKNRsEVIVRAWFLQEVTPRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCF 214
Cdd:COG0566 16 RDKKYREEEGLflAEGRHAVEEALKAG-REIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 215 LIKKRQGMDVREYLKTAGEHDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV-QDAALLESGAAVRTAEGGAEHVKAINA 293
Cdd:COG0566 95 VVRPPEYADLEDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILpKRRADPYNPKVVRASAGALFHVPVARV 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 294 DDFLSVLTEFRNAGYTIVTTSSHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGIL 373
Cdd:COG0566 175 TNLADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAIL 254
|
250
....*....|
gi 684992527 374 LSEWWRQNQA 383
Cdd:COG0566 255 LYEAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
236-377 |
5.37e-51 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 167.22 E-value: 5.37e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 236 CVLALEDVGNPHNLGGIMRSCAHFGVKGV-LVQDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTS 314
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGViLSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 684992527 315 SHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEW 377
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
237-374 |
2.35e-37 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 131.88 E-value: 2.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV--QDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTS 314
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILvePRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 315 sHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILL 374
Cdd:pfam00588 83 -LGGKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
237-377 |
1.22e-35 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 127.12 E-value: 1.22e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLVQ--DAALLeSGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTS 314
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPkrRSAPL-TPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 684992527 315 SHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEW 377
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
147-380 |
1.73e-30 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 116.67 E-value: 1.73e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 147 RVYGENACQALFKNRSEVivrawFLQEVT--PRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCFLIKKRQGMDV 224
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQRV-----FILKGLesKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 225 REYLKTAGEHDC--VLALEDVGNPHNLGGIMRSCAHFGVKGVLV--QDAALLESGAaVRTAEGGAEHVKAINADDFLSVL 300
Cdd:TIGR00186 78 NDLYKTAKSKKQpfLLILDEITDPHNLGAILRTAEAFGVDGVILpkRRSAPLNSTV-VKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 301 TEFRNAGYTIVTTSSHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEWWRQ 380
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
237-377 |
1.89e-28 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 108.47 E-value: 1.89e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGV-LVQDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTSS 315
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIyLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGLEL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 684992527 316 HKGTV-LSKATL--PAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEW 377
Cdd:cd18082 81 TDGSIpLSEFKFkkPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
237-376 |
4.12e-27 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 105.24 E-value: 4.12e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVkgvlvQDAALLESGAAV----RTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVT 312
Cdd:cd18092 18 TVVLENVHDPHNASAVLRTCDAFGV-----QDVHVIEPKNKFkknrGVAMGADKWLDVHRHDSTEECLAALKEQGYRIVA 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 684992527 313 TSSHKGTV-LSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSE 376
Cdd:cd18092 93 TSLSPDAVpLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYE 157
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
237-376 |
1.25e-26 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 103.75 E-value: 1.25e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLVQD---AALleSGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTT 313
Cdd:cd18105 2 WLLLDEITDPQNLGAILRSAYFLGVDGVVVSSknsAPL--SPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGT 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 684992527 314 SSHKGTVLSKATLPA----------KTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGK-----VESLNISVATGILLSE 376
Cdd:cd18105 80 SAPPSASSDKKTIPAnelselllekPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaenpgVDSLNVSVAAGILLHS 157
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
237-377 |
8.52e-24 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 95.68 E-value: 8.52e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLV-QDAALLESGAAVRTAEGGAEHVKaINADDFLSVLTEfRNAGYTIVTTSS 315
Cdd:cd18109 2 TLALDGIQDPGNLGTIIRTADWFGIRQIICsPDTVDPYNPKVVQASMGSIFRVQ-IHYTDLPALLAE-LKKAFPVYGADL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 684992527 316 HkGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGK-VESLNISVATGILLSEW 377
Cdd:cd18109 80 D-GENLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKgAESLNVAVATAILLSEF 141
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
245-377 |
4.00e-22 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 91.05 E-value: 4.00e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 245 NPHNLGGIMRSCAHFGVKGVLVQDAALLESGAAVRTAEGGAEHV--KAINADDFLSVLTEFRNAGYTIV----TTSShkg 318
Cdd:cd18091 10 KPPNLGGLCRTCEIFGVSKLVLPNLAVVEDKQFKALSVSAEKWLpiEEVKPEDLLPYLKEKKQEGYTIVgleqTANS--- 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 684992527 319 TVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEW 377
Cdd:cd18091 87 VSLHDFQFPKKTVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYEY 145
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
236-377 |
6.03e-20 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 84.96 E-value: 6.03e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 236 CVLALEDVGNPHNLGGIMRSCAHFGVKGVLVQDAALLesgaAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIVTTSS 315
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHLVGRRKF----NPFGAMGTDRHVKFRHFDTLAEAKEYLKERGIRLVGVEI 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 684992527 316 HKGTV-LSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGK-VESLNISVATGILLSEW 377
Cdd:cd18096 77 VPGAEpIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGSgTASLNVSVAASIVLHHF 140
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
148-380 |
1.58e-19 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 86.94 E-value: 1.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 148 VYGENACQALFKNRSEVIVRAWFLQ-----EVTPRFRDALRW----MAANRKAYhvveeDEliKASGTEHHGGVCFLI-- 216
Cdd:PRK11181 5 IYGIHAVQALLERAPERFIEVFVLKgredkRLLPLINELEAQgiviQLANRQTL-----DE--KAEGAVHQGIIARVKpg 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 217 KKRQGMDVREYLKTAgEHDCVLALEDVGNPHNLGGIMRSCAHFGVKGVLV-QDAALLESGAAVRTAEGGAEHVKAINADD 295
Cdd:PRK11181 78 RQLQENDLPDLLASL-EQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVpKDRSAQLNATAKKVACGAAETVPLIRVTN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 296 FLSVLTEFRNAGYTIVTTSSHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLS 375
Cdd:PRK11181 157 LARTMRMLQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLF 236
|
....*
gi 684992527 376 EWWRQ 380
Cdd:PRK11181 237 EAVRQ 241
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
237-381 |
1.14e-18 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 81.86 E-value: 1.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLVQDAAL-LESGAAVRTAEGGAEHVKAINADDfLSVLTEFRNAGYTIVTTSS 315
Cdd:cd18104 2 ILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTdLFNPNVIRASLGAVFTLPVAEASS-EETLAWLKENKIRILATTP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 684992527 316 HKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEWWRQN 381
Cdd:cd18104 81 KAEKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYEALRQR 146
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
236-377 |
2.18e-17 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 77.99 E-value: 2.18e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 236 CVLALEDVGNPHNLGGIMRSCAHFGVKGV-LVQDAALLESGAAVRTAEGGAEHVKAINADDFLSVLTEFRNAGYTIV--- 311
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIyLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIale 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 684992527 312 TTSSHKGtvLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEW 377
Cdd:cd18097 81 TTENSVP--LHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
237-376 |
1.29e-15 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 73.19 E-value: 1.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLVQ-DAALLESGAAVRTAEGGAEHVKAINAD---DFLSVLTEFRNAG--YTI 310
Cdd:cd18107 2 VVLFDRPTSPGNLGTIIRSADALGAHGLVVTgHAADVYDPKTIRASTGSLFSLPIVRVPsnrELEDWVEARKARGtpLQL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 684992527 311 VTTSSHKGTVLSKATLPAKTVIVLGQEGDGLSdSAWQQ-GDVKVSIGGTGKVESLNISVATGILLSE 376
Cdd:cd18107 82 VGTDEHGDHQIADHDFTRPTLLLIGNETAGLS-AAWRElCDETVSIPMAGSASSLNAACAASIFLYE 147
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
233-383 |
4.76e-14 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 70.79 E-value: 4.76e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 233 EHDCVLALEDVGNPHNLGGIMRSCAHFGVKGVlvqDAALLESGAAVR--TAEGGAEHVKAINADDFLSVLTEFRNAGYTI 310
Cdd:PRK11081 17 QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV---HAVWPGSRMRTMgsTAAGSNSWVQVKTHRTIGDAVAHLKGQGMQI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 311 VTTSshkgtvLS-KA--------TLPakTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEWWRQN 381
Cdd:PRK11081 94 LATH------LSdTAvdfreidyTRP--TCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
|
..
gi 684992527 382 QA 383
Cdd:PRK11081 166 QN 167
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
246-381 |
1.14e-10 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 59.00 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 246 PHNLGGIMRSCAHFGVK-------GVLVQDAALLESG------AAVRtaeggaEHVkaiNADDFLSvltefRNAGYTIVT 312
Cdd:cd18094 10 PQNTGNIARTCAATGARlhlieplGFSLDDKRLKRAGldywdhVDLT------VHD---SWEAFLE-----ALPPGRLFL 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 313 TSSHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQ-GDVKVSIGGTGKVESLNISVATGILLSEWWRQN 381
Cdd:cd18094 76 FTTKGTKPYTDFDFKPGDYLVFGRESTGLPEEILDAfPDRRLRIPMRPKVRSLNLSNSVAIVLYEALRQL 145
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
148-220 |
1.38e-10 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 56.87 E-value: 1.38e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 684992527 148 VYGENACQALFKNRSEvIVRAWFLQEV-TPRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCFLIKKRQ 220
Cdd:pfam08032 2 IYGRHAVLEALKSGPE-IKKLYLTEGRrDPRLKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKPYE 74
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
237-376 |
1.31e-08 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 53.25 E-value: 1.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 237 VLALEDVGNPHNLGGIMRSCAHFGVKGVLvqdaaLLESGAA-------VRTAEGGAEHVKAINAD--DFLSVLtefRNAG 307
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIV-----LVDSDLAtvadrrlLRASRGYVFSLPVVLADreEAVAFL---RDND 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 308 YTIVTTSSHKGTVLSKAT-LPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSE 376
Cdd:cd18108 74 IPLMTLDADGDVPVKELGdRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
148-218 |
1.58e-07 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 47.92 E-value: 1.58e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 684992527 148 VYGENACQALFKNRsEVIVRAWFLQEVTPRFRDALRWMAANRKAYHVVEEDELIKASGTEHHGGVCFLIKK 218
Cdd:smart00967 1 IEGRHAVEEALKSG-RRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
246-377 |
4.07e-07 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 49.03 E-value: 4.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 246 PHNLGGIMRSCAHFGVKG-VLVQDAALLESGAAVRTAeGGAEHV--KAINADDFLSVLTEFRnagyTIVTTSSHKGTVLS 322
Cdd:cd18093 11 PGNIGAVARAMKNFGLSDlRLVNPRCDDPEEAARALA-SGAEDVleNAKVYDTLEEALADCD----LVVATTARPRGLRR 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 684992527 323 KATLPA-------------KTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGKVESLNISVATGILLSEW 377
Cdd:cd18093 86 PLLTPRelaellkehaaggKVALVFGREDSGLTNEELALCDLLVTIPTNPEYPSLNLAQAVAIVLYEL 153
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
246-381 |
1.23e-05 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 44.64 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 246 PHNLGGIMRSCAHFGVKGVLVQ-------DAALlesgaavRTAegG---AEHVKAI---NADDFLSvltefRNAGYTIVT 312
Cdd:COG0219 12 PQNTGNIIRLCAATGARLHLIEplgfsldDKKL-------KRA--GldyWELVDLTvhdSWEAFLE-----ALPGGRLFL 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 313 TSSHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQG-DVKVSIGGTGKVESLNISVATGILLSEWWRQN 381
Cdd:COG0219 78 FTTKGTKPYTDVDYQPGDVLLFGRETAGLPEEVLAAPaDQRLRIPMRPGVRSLNLSNAVAIVLYEALRQL 147
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
246-376 |
2.42e-05 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 43.78 E-value: 2.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 246 PHNLGGIMRSCAHFGVKGVLVQ-------DAALLESGAavrtaeGGAEHVKAIN-----------ADDFLSVL--TEFRN 305
Cdd:cd18106 11 PGNLGSILRSAAAAGCSKVLLTkgcvdpwEPKVLRAGA------GAHFRLPIYGnlswddipnylPDDSKVFLadNNLPV 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 684992527 306 AGYTIVTTSShkgtvlskatlpAKTVIVLGQEGDGLSDSAWQ----QGDVKVSIGGTGKVESLNISVATGILLSE 376
Cdd:cd18106 85 QPYDSIDYCS------------GPIVLVIGGETHGVSPEAYKlahsTGGSRVHIPLANGVDSLNSAVAASILLFE 147
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
236-374 |
2.46e-05 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 43.79 E-value: 2.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 684992527 236 CVLALEDVGNPHNLGGIMRSCAHFGVKGVLVQDAALLESGAAVRTAEGGA----EHVKAInaDDFLSVLTEfrnaGYTIV 311
Cdd:cd18098 1 FAIGIENPKTPKNVGTLWRAAGCLGASFVFTIGARYKRRKQSTDTSKAWRhiplFHYDDL--EDLAEPLPF----GAVLV 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 684992527 312 TTS-SHKGTVLSKATLPAKTVIVLGQEGDGLSDSAWQQGDVKVSIGGTGkveSLNISVATGILL 374
Cdd:cd18098 75 AVElTEGATPLPDFKHPDRAVYLLGPEDGGLPQEVLARCHHVVYLPTRG---SLNVAVAGSIVL 135
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