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Conserved domains on  [gi|700405100|gb|KGO35236|]
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4Fe-4S ferredoxin [Desulfobulbus sp. Tol-SR]

Protein Classification

4Fe-4S dicluster domain-containing protein( domain architecture ID 11586849)

4Fe-4S dicluster domain-containing protein similar to Escherichia coli hydrogenase-4 component A, a probable electron transfer protein for hydrogenase 4

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 12-171 2.46e-97

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


:

Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 281.50  E-value: 2.46e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDAGCMK 91
Cdd:cd10562    1 MLVDTSKCTACRGCQVACKQWNQLPAEKTPFTGSYQNPPDLTPNTWTLIRFYEHEEDNGGIRWLFRKRQCMHCTDAACVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  92 ICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGDREE 170
Cdd:cd10562   81 VCPTGALYKTENGAVVVDEDKCIGCGYCVAACPFDVPRYDETtNKITKCTLCFDRIENGMQPACVKTCPTGALTFGDRDE 160


                 .
gi 700405100 171 L 171
Cdd:cd10562  161 L 161
Form-deh_trans pfam09163
Formate dehydrogenase N, transmembrane; Members of this family are predominantly found in the ...
 213-255 1.52e-08

Formate dehydrogenase N, transmembrane; Members of this family are predominantly found in the beta subunit of formate dehydrogenase, and consist of a single transmembrane helix. They act as a transmembrane anchor, and allow for conduction of electrons within the protein.


:

Pssm-ID: 430440  Cd Length: 43  Bit Score: 49.54  E-value: 1.52e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 700405100  213 IPSSVNFWHTYLKPLSVIGLGGVVAAAAIHYLAIGPHKDNNEE 255
Cdd:pfam09163   1 ISPSVELWKGVLKPLGAAGMGAAALAGFFHYITVGPNKVEEEE 43
 
Name Accession Description Interval E-value
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 12-171 2.46e-97

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 281.50  E-value: 2.46e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDAGCMK 91
Cdd:cd10562    1 MLVDTSKCTACRGCQVACKQWNQLPAEKTPFTGSYQNPPDLTPNTWTLIRFYEHEEDNGGIRWLFRKRQCMHCTDAACVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  92 ICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGDREE 170
Cdd:cd10562   81 VCPTGALYKTENGAVVVDEDKCIGCGYCVAACPFDVPRYDETtNKITKCTLCFDRIENGMQPACVKTCPTGALTFGDRDE 160


                 .
gi 700405100 171 L 171
Cdd:cd10562  161 L 161
FDH-beta TIGR01582
formate dehydrogenase, beta subunit, Fe-S containing; This model represents the beta subunit ...
 11-255 5.96e-76

formate dehydrogenase, beta subunit, Fe-S containing; This model represents the beta subunit of the gamma-proteobacterial formate dehydrogenase. This subunit contains four 4Fe-4S clusters and is involved in transmitting electrons from the alpha subunit (TIGR01553) at the periplasmic space to the gamma subunit which spans the cytoplasmic membrane. In addition to the gamma proteobacteria, a sequence from Aquifex aolicus falls within the scope of this model. This appears to be the case for the alpha, gamma and epsilon (accessory protein TIGR01562) chains as well. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport]


Pssm-ID: 273705 [Multi-domain]  Cd Length: 283  Bit Score: 231.72  E-value: 5.96e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   11 AILVTPELCIGCRACQVACKSWNQL-PGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENpVRWLFVSRRCMHCDDAGC 89
Cdd:TIGR01582  23 AKLIDVSSCIGCKACQAACQEWNDTtPPILSRKVGGYQNPPDLLPETFTLMRFKEGEESDG-LEWLIRKDGCMHCREPGC 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   90 MKICPS-GALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYD-ADGKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGD 167
Cdd:TIGR01582 102 LKACPApGAIIQYQNGIVDFDHSKCIGCGYCIVGCPFNIPRYDkVDNRPYKCTLCIDRVSVGQEPACVKTCPTNAISFGF 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  168 REELIGAAKK-------EGF--ATIYGEQDLGGLGSVYAF--KEEPKLY-GMIENPAIPSSVNFWHTYLKPLSVIGLGGV 235
Cdd:TIGR01582 182 KEDMKERAEKrvadlksRGYpnAGLYDPPGVGGTHVMYVLhhGDKPKDYqDLPEDPRIDASVGLWKGVLKTIGSIAMGGT 261

                         250       260
                  ....*....|....*....|
gi 700405100  236 VAAAAIHYLAIGPHKDNNEE 255
Cdd:TIGR01582 262 ALGVFLHLILWGPNKVLGGK 281
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 6-177 1.21e-68

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 209.80  E-value: 1.21e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   6 SNNRKAILVTPELCIGCRACQVACKSWNQLPgiktkntgsyqnppdlASAAYNIIRYNEVPSQENpVRWLFVSRRCMHCD 85
Cdd:COG0437    2 SMKRYGMVIDLTKCIGCRACVVACKEENNLP----------------VGVTWRRVRRYEEGEFPN-VEWLFVPVLCNHCD 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  86 DAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALK 164
Cdd:COG0437   65 DPPCVKVCPTGATYKREDGIVLVDYDKCIGCRYCVAACPYGAPRFNPEtGVVEKCTFCADRLDEGLLPACVEACPTGALV 144

                        170
                 ....*....|...
gi 700405100 165 FGDREELIGAAKK 177
Cdd:COG0437  145 FGDLDDPESEVSK 157
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
18-210 1.42e-49

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 165.61  E-value: 1.42e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  18 LCIGCRACQVACKSWNQLPGiKTKNTGSYQNPPDLASAAYNIIR----YNEVPSQENPVRWLFVSRRCMHCDDAGCMKIC 93
Cdd:PRK10882  46 LCVGCQACVTKCQEINFPER-NPQGEQTWDNPDKLSPYTNNIIKvwksGTGVNKDQEENGYAYIKKQCMHCVDPNCVSVC 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  94 PSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYDAD---GKVTKCHLC----FDRIAAGMNPACVKTCPTGALKF 165
Cdd:PRK10882 125 PVSALTKDPKtGIVHYDKDVCTGCRYCMVACPFNVPKYDYNnpfGAIHKCELCnqkgVERLDKGGLPGCVEVCPTGAVIF 204

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 700405100 166 GDREELIGAAK-----KEGFATIYGEQDLGGLGSV--YAFKEEPKLYGMIEN 210
Cdd:PRK10882 205 GTREELLAEAKrrlalKPGSEYHYPRQTLKSGDTYlhTVPKYYPHVYGEKEG 256
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 72-168 7.23e-39

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 130.83  E-value: 7.23e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   72 VRWLFVSRRCMHCDDAGCMKICPSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAG 149
Cdd:pfam13247   1 VDWLFFPEQCRHCLNPPCKASCPVGAIYKDEEtGAVLLDEKTCRGWRECVSACPYNIPRYNDEtGKAEKCDMCYDRVEAG 80

                          90
                  ....*....|....*....
gi 700405100  150 MNPACVKTCPTGALKFGDR 168
Cdd:pfam13247  81 LLPACVQTCPTGAMNFGDR 99
Form-deh_trans pfam09163
Formate dehydrogenase N, transmembrane; Members of this family are predominantly found in the ...
 213-255 1.52e-08

Formate dehydrogenase N, transmembrane; Members of this family are predominantly found in the beta subunit of formate dehydrogenase, and consist of a single transmembrane helix. They act as a transmembrane anchor, and allow for conduction of electrons within the protein.


Pssm-ID: 430440  Cd Length: 43  Bit Score: 49.54  E-value: 1.52e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 700405100  213 IPSSVNFWHTYLKPLSVIGLGGVVAAAAIHYLAIGPHKDNNEE 255
Cdd:pfam09163   1 ISPSVELWKGVLKPLGAAGMGAAALAGFFHYITVGPNKVEEEE 43
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 111-170 6.69e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.84  E-value: 6.69e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 700405100 111 DKCIGCKLCVNACP-----FDvprydaDGKV---TKCHLCFdriaagmnpACVKTCPTGALKFGDREE 170
Cdd:NF038196 185 DKCIGCGICAKVCPvnnieME------DGKPvwgHNCTHCL---------ACIHRCPKEAIEYGKKTK 237
 
Name Accession Description Interval E-value
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 12-171 2.46e-97

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 281.50  E-value: 2.46e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDAGCMK 91
Cdd:cd10562    1 MLVDTSKCTACRGCQVACKQWNQLPAEKTPFTGSYQNPPDLTPNTWTLIRFYEHEEDNGGIRWLFRKRQCMHCTDAACVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  92 ICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGDREE 170
Cdd:cd10562   81 VCPTGALYKTENGAVVVDEDKCIGCGYCVAACPFDVPRYDETtNKITKCTLCFDRIENGMQPACVKTCPTGALTFGDRDE 160


                 .
gi 700405100 171 L 171
Cdd:cd10562  161 L 161
FDH-N cd10558
The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS ...
 11-206 2.19e-81

The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS subunit of formate dehydrogenase-N (FDH-N), a member of the DMSO reductase family. FDH-N is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. Thus, FDH-N is a major component of nitrate respiration of Escherichia coli. This integral membrane enzyme forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups.


Pssm-ID: 319880 [Multi-domain]  Cd Length: 208  Bit Score: 243.06  E-value: 2.19e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  11 AILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENpVRWLFVSRRCMHCDDAGCM 90
Cdd:cd10558    1 AKLIDVSKCIGCKACQVACKEWNDLRAEVGHNVGTYQNPADLSPETWTLMKFREVEDNGK-LEWLIRKDGCMHCADPGCL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  91 KICPS-GALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDA-DGKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGDR 168
Cdd:cd10558   80 KACPSpGAIVQYANGIVDFQSDKCIGCGYCIKGCPFDIPRISKdDNKMYKCTLCSDRVSVGLEPACVKTCPTGALHFGTK 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100 169 EELIGAAKK-------EGF--ATIYGEQDLGGLGSVYAFKEEPKLYG 206
Cdd:cd10558  160 EDMLALAEKrvaalkeRGYtnAGLYDPKGVGGTHVMYVLHHADKPEG 206
HybA_like cd10561
the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 ...
 11-196 2.11e-79

the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 (Hyd-2), an enzyme that catalyzes the reversible oxidation of H2 to protons and electrons. Hyd-2 is membrane-associated and forms an unusual heterotetrameric [NiFe]-hydrogenase in that it lacks the typical cytochrome b membrane anchor subunit that transfers electrons to the quinone pool. The electron transfer subunit of Hyd-2 (HybA) which is predicted to contain four iron-sulfur clusters, is essential for electron transfer from Hyd-2 to menaquinone/demethylmenaquinone (MQ/DMQ) to couple hydrogen oxidation to fumarate reduction.


Pssm-ID: 319883 [Multi-domain]  Cd Length: 196  Bit Score: 237.50  E-value: 2.11e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  11 AILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENpvRWLFVSRRCMHCDDAGCM 90
Cdd:cd10561    1 GVLYDTTRCIGCRACEVACKEWNGLPAEDTAFGPGWDNPRDLSAKTYTVIKRYEVETGGK--GFVFVKRQCMHCLDPACV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  91 KICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRY---DADGKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGD 167
Cdd:cd10561   79 SACPVGALRKTPEGPVTYDEDKCIGCRYCMVACPFNIPKYewdSANPKIRKCTMCYDRLKEGKQPACVEACPTGALLFGK 158

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 700405100 168 REELIGAAKK-------EGFATIYGEQDLGGLGSVY 196
Cdd:cd10561  159 REELLAEAKRriaanpgRYVDHVYGEKEAGGTSVLY 194
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 18-214 1.01e-78

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 236.90  E-value: 1.01e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  18 LCIGCRACQVACKSWNQLPGIKTKNTG-SYQNPPDLASAAYNIIRYNEVPSQENPV------RWLFVSRRCMHCDDAGCM 90
Cdd:cd10560    8 ICIGCKACEVACKQWNQLPADGYDFSGmSYDNTGDLSASTWRHVKFIERPTEDGPAneggdlQWLFMSDVCKHCTDAGCL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  91 KICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDA-DGKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGDRE 169
Cdd:cd10560   88 EACPTGAIFRTEFGTVYIQPDICNGCGYCVAACPFGVIDRNEeTGRAHKCTLCYDRLKDGLEPACAKACPTGSIQFGPLE 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 700405100 170 ELIGAAKK---------EGFATIYG---EQDLGGLGSVYAFKEEPKLYGMIENPAIP 214
Cdd:cd10560  168 ELRERARArveqlheqgVVEAYLYGadpTEGYGGLNAFFLLLDKPEVYGLPADPLLP 224
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 12-166 2.42e-76

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 228.44  E-value: 2.42e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDAGCMK 91
Cdd:cd16366    1 FLVDTSRCTGCRACQVACKQWNGLPAEKTEFTGSYQNPPDLTAHTWTLVRFYEVEKPGGDLSWLFRKDQCMHCTDAGCLA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700405100  92 ICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFG 166
Cdd:cd16366   81 ACPTGAIIRTETGTVVVDPETCIGCGYCVNACPFDIPRFDEEtGRVAKCTLCYDRISNGLQPACVKTCPTGALTFG 156
FDH-beta TIGR01582
formate dehydrogenase, beta subunit, Fe-S containing; This model represents the beta subunit ...
 11-255 5.96e-76

formate dehydrogenase, beta subunit, Fe-S containing; This model represents the beta subunit of the gamma-proteobacterial formate dehydrogenase. This subunit contains four 4Fe-4S clusters and is involved in transmitting electrons from the alpha subunit (TIGR01553) at the periplasmic space to the gamma subunit which spans the cytoplasmic membrane. In addition to the gamma proteobacteria, a sequence from Aquifex aolicus falls within the scope of this model. This appears to be the case for the alpha, gamma and epsilon (accessory protein TIGR01562) chains as well. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport]


Pssm-ID: 273705 [Multi-domain]  Cd Length: 283  Bit Score: 231.72  E-value: 5.96e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   11 AILVTPELCIGCRACQVACKSWNQL-PGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENpVRWLFVSRRCMHCDDAGC 89
Cdd:TIGR01582  23 AKLIDVSSCIGCKACQAACQEWNDTtPPILSRKVGGYQNPPDLLPETFTLMRFKEGEESDG-LEWLIRKDGCMHCREPGC 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   90 MKICPS-GALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYD-ADGKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGD 167
Cdd:TIGR01582 102 LKACPApGAIIQYQNGIVDFDHSKCIGCGYCIVGCPFNIPRYDkVDNRPYKCTLCIDRVSVGQEPACVKTCPTNAISFGF 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  168 REELIGAAKK-------EGF--ATIYGEQDLGGLGSVYAF--KEEPKLY-GMIENPAIPSSVNFWHTYLKPLSVIGLGGV 235
Cdd:TIGR01582 182 KEDMKERAEKrvadlksRGYpnAGLYDPPGVGGTHVMYVLhhGDKPKDYqDLPEDPRIDASVGLWKGVLKTIGSIAMGGT 261

                         250       260
                  ....*....|....*....|
gi 700405100  236 VAAAAIHYLAIGPHKDNNEE 255
Cdd:TIGR01582 262 ALGVFLHLILWGPNKVLGGK 281
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 6-177 1.21e-68

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 209.80  E-value: 1.21e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   6 SNNRKAILVTPELCIGCRACQVACKSWNQLPgiktkntgsyqnppdlASAAYNIIRYNEVPSQENpVRWLFVSRRCMHCD 85
Cdd:COG0437    2 SMKRYGMVIDLTKCIGCRACVVACKEENNLP----------------VGVTWRRVRRYEEGEFPN-VEWLFVPVLCNHCD 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  86 DAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALK 164
Cdd:COG0437   65 DPPCVKVCPTGATYKREDGIVLVDYDKCIGCRYCVAACPYGAPRFNPEtGVVEKCTFCADRLDEGLLPACVEACPTGALV 144

                        170
                 ....*....|...
gi 700405100 165 FGDREELIGAAKK 177
Cdd:COG0437  145 FGDLDDPESEVSK 157
W-FDH cd10559
tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit ...
 11-177 3.23e-62

tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit of Tungsten-containing formate dehydrogenase (W-FDH), a member of the DMSO reductase family. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319881 [Multi-domain]  Cd Length: 200  Bit Score: 193.80  E-value: 3.23e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  11 AILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDAGCM 90
Cdd:cd10559    1 SFLIDTTRCTACRGCQVACKQWNQLPAEQTKNTGSHQNPPDLSANTYKLVRFNEVRNENGKPDWLFFPDQCRHCVTPPCK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  91 KIC---PSGALYRTAEGAVAF-DRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKF 165
Cdd:cd10559   81 DAAdmvPGAVIQDEATGAVVFtEKTAELDFDDVLSACPYNIPRKNEAtGRIVKCDMCIDRVSNGLQPACVKACPTGAMNF 160

                        170
                 ....*....|..
gi 700405100 166 GDREELIGAAKK 177
Cdd:cd10559  161 GDRDEMLAMASK 172
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 19-167 7.89e-53

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 169.25  E-value: 7.89e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  19 CIGCRACQVACKSWNQLPgiktkntgsyqnppdlASAAYNIIRYNEVPSQENPVRwLFVSRRCMHCDDAGCMKICPSGAL 98
Cdd:cd10551    8 CIGCGACVVACKAENNVP----------------PGVFRNRVLEYEVGEYPNVKR-TFLPVLCNHCENPPCVKVCPTGAT 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  99 YRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-------------GKVTKCHLCFDRIAAGMNPACVKTCPTGALKF 165
Cdd:cd10551   71 YKREDGIVLVDYDKCIGCRYCMAACPYGARYFNPEephefgevpvrpkGVVEKCTFCYHRLDEGLLPACVEACPTGARIF 150


                 ..
gi 700405100 166 GD 167
Cdd:cd10551  151 GD 152
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 11-166 1.91e-52

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 166.97  E-value: 1.91e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  11 AILVTPELCIGCRACQVACKSWNQLPgiktkntgsyqnppdlasAAYNIIRYNEVPSQENPVRWL-FVSRRCMHCDDAGC 89
Cdd:cd16371    1 GFYFDQERCIGCKACEIACKDKNDLP------------------PGVNWRRVYEYEGGEFPEVFAyFLSMSCNHCENPAC 62

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 700405100  90 MKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFG 166
Cdd:cd16371   63 VKVCPTGAITKREDGIVVVDQDKCIGCGYCVWACPYGAPQYNPEtGKMDKCDMCVDRLDEGEKPACVAACPTRALDFG 140
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
18-210 1.42e-49

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 165.61  E-value: 1.42e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  18 LCIGCRACQVACKSWNQLPGiKTKNTGSYQNPPDLASAAYNIIR----YNEVPSQENPVRWLFVSRRCMHCDDAGCMKIC 93
Cdd:PRK10882  46 LCVGCQACVTKCQEINFPER-NPQGEQTWDNPDKLSPYTNNIIKvwksGTGVNKDQEENGYAYIKKQCMHCVDPNCVSVC 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  94 PSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYDAD---GKVTKCHLC----FDRIAAGMNPACVKTCPTGALKF 165
Cdd:PRK10882 125 PVSALTKDPKtGIVHYDKDVCTGCRYCMVACPFNVPKYDYNnpfGAIHKCELCnqkgVERLDKGGLPGCVEVCPTGAVIF 204

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 700405100 166 GDREELIGAAK-----KEGFATIYGEQDLGGLGSV--YAFKEEPKLYGMIEN 210
Cdd:PRK10882 205 GTREELLAEAKrrlalKPGSEYHYPRQTLKSGDTYlhTVPKYYPHVYGEKEG 256
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 12-166 2.03e-49

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 159.09  E-value: 2.03e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACKSWNQLPGIKTKNtgsyqnppdlasaaynIIRYNEVPsqenPVRWLFVSRRCMHCDDAGCMK 91
Cdd:cd04410    1 LVVDLDRCIGCGTCEVACKQEHGLRPGPDWS----------------RIKVIEGG----GLERAFLPVSCMHCEDPPCVK 60

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700405100  92 ICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFG 166
Cdd:cd04410   61 ACPTGAIYKDEDGIVLIDEDKCIGCGSCVEACPYGAIVFDPEpGKAVKCDLCGDRLDEGLEPACVKACPTGALTFG 136
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 12-172 4.62e-48

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 155.51  E-value: 4.62e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACKSWNqlpgiktkntgsyqnppdlaSAAYNIIRYnevpsqenPVRWLF-VSRRCMHCDDAGCM 90
Cdd:cd16374    1 VYVDPERCIGCRACEIACAREH--------------------SGKPRISVE--------VVEDLAsVPVRCRHCEDAPCM 52

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  91 KICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDADGKV-TKCHLCFDRIAAGMNPACVKTCPTGALKFGDRE 169
Cdd:cd16374   53 EVCPTGAIYRDEDGAVLVDPDKCIGCGMCAMACPFGVPRFDPSLKVaVKCDLCIDRRREGKLPACVEACPTGALKFGDIE 132


                 ...
gi 700405100 170 ELI 172
Cdd:cd16374  133 ELL 135
PhsB_like cd10553
uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This ...
 19-166 5.28e-40

uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This family includes beta FeS subunits of anaerobic DMSO reductase (DMSOR) superfamily that have yet to be characterized. DMSOR consists of a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and the tungsten-containing formate dehydrogenase (FDH-T). Examples of heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319875 [Multi-domain]  Cd Length: 146  Bit Score: 135.18  E-value: 5.28e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  19 CIGCRACQVACKSWNQLPgiktkntgsyqnppdlASAAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDAGCMKICPSGAL 98
Cdd:cd10553   12 CIGCLACEVHCKVKNNLP----------------VGPRLCRIFAVGPKMVGGKPRLKFVYMSCFHCENPWCVKACPTGAM 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  99 Y-RTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFG 166
Cdd:cd10553   76 QkREKDGIVYVDQELCIGCKACIEACPWGIPQWNPAtGKVVKCDYCMDRIDQGLKPACVTGCTTHALSFV 145
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 72-168 7.23e-39

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 130.83  E-value: 7.23e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   72 VRWLFVSRRCMHCDDAGCMKICPSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAG 149
Cdd:pfam13247   1 VDWLFFPEQCRHCLNPPCKASCPVGAIYKDEEtGAVLLDEKTCRGWRECVSACPYNIPRYNDEtGKAEKCDMCYDRVEAG 80

                          90
                  ....*....|....*....
gi 700405100  150 MNPACVKTCPTGALKFGDR 168
Cdd:pfam13247  81 LLPACVQTCPTGAMNFGDR 99
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 12-165 4.27e-37

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 127.31  E-value: 4.27e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACkSWnqlpgiktKNTGSYqNPpdlASAAYNIIRYNEVPsqenpvrwLFVSRRCMHCDDAGCMK 91
Cdd:cd10550    1 LVVDPEKCTGCRTCELAC-SL--------KHEGVF-NP---SLSRIRVVRFEPEG--------LDVPVVCRQCEDAPCVE 59

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700405100  92 ICPSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCfdriaaGMNPACVKTCPTGALKF 165
Cdd:cd10550   60 ACPVGAISRDEEtGAVVVDEDKCIGCGMCVEACPFGAIRVDPEtGKAIKCDLC------GGDPACVKVCPTGALEF 129
DMSOR_beta_like cd16369
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 10-172 1.70e-35

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319891 [Multi-domain]  Cd Length: 172  Bit Score: 124.42  E-value: 1.70e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  10 KAILVTPELCIGCRACQVACKSWNQLPGiKTKNTGSYQNPPDLASAAYNIirynevpsqenpvrwlfvsrrCMHCDDAGC 89
Cdd:cd16369    2 KEFFIDPSRCIGCRACVAACRECGTHRG-KSMIHVDYIDRGESTQTAPTV---------------------CMHCEDPTC 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  90 MKICPSGALYRTAEGAV-AFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCFDRIAAGMNPACVKTCPTGALKFGD 167
Cdd:cd16369   60 AEVCPADAIKVTEDGVVqSALKPRCIGCSNCVNACPFGVPKYDEErNLMMKCDMCYDRTSVGKAPMCASVCPSGALFYGT 139


                 ....*
gi 700405100 168 REELI 172
Cdd:cd16369  140 REEIQ 144
CooF_like cd10563
CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...
 12-166 5.92e-33

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.


Pssm-ID: 319885 [Multi-domain]  Cd Length: 140  Bit Score: 116.97  E-value: 5.92e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACK---SwnqlpgiKTKNTGSYQNPPDLASAAYNIIRYNEVPSQENpvrwlfvsrrCMHCDDAG 88
Cdd:cd10563    2 IFIDEEKCLGCKLCEVACAvahS-------KSKDLIKAKLEKERPRPRIRVEESGGRSFPLQ----------CRHCDEPP 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  89 CMKICPSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYDADGKV-TKCHLCFDRiaagMNPACVKTCPTGALKFG 166
Cdd:cd10563   65 CVKACMSGAMHKDPEtGIVIHDEEKCVGCWMCVMVCPYGAIRPDKERKVaLKCDLCPDR----ETPACVEACPTGALVLE 140
DMSOR_beta_like cd16368
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 11-176 1.86e-32

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319890 [Multi-domain]  Cd Length: 200  Bit Score: 117.52  E-value: 1.86e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  11 AILVTPELCIGCR-----ACQVACKSWNQ--LPGIKTKNTGSY---QNPPDLASAAYNIIR---YNEVPSQENPVRW--- 74
Cdd:cd16368    2 ATLIDLTKCDGCPgesipACVRACREKNQarFPEPVSKPIQPYwprKRIEDWSDKRDVTDRltpYNWLYVQKLTVDTagg 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  75 ---LFVSRRCMHCDDAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPR--------------YDADGKVT 137
Cdd:cd16368   82 ekeVFIPRRCMHCDNPPCAKLCPFGAARKTPEGAVYIDDDLCFGGAKCRDVCPWHIPQrqagvgiylhlapeYAGGGVMY 161

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 700405100 138 KCHLCFDRIAAGMNPACVKTCPTGALKFGDREELIGAAK 176
Cdd:cd16368  162 KCDLCKDLLAQGKPPACIEACPKGAQYFGPRKEMVALAR 200
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
9-167 2.86e-31

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 112.44  E-value: 2.86e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   9 RKAILVTPELCIGCRACQVACkswnqlpgiktkntgsyqnppdlaSAAYNIIRYnevpsqENPVRWLFVSRR-------- 80
Cdd:COG1142    2 NKFIIADPEKCIGCRTCEAAC------------------------AVAHEGEEG------EPFLPRIRVVRKagvsapvq 51

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  81 CMHCDDAGCMKICPSGALYRTaEGAVAFDRDKCIGCKLCVNACPFDVPR---YDADGKVTKCHLCFDRIAAgmnPACVKT 157
Cdd:COG1142   52 CRHCEDAPCAEVCPVGAITRD-DGAVVVDEEKCIGCGLCVLACPFGAITmvgEKSRAVAVKCDLCGGREGG---PACVEA 127

                        170
                 ....*....|
gi 700405100 158 CPTGALKFGD 167
Cdd:COG1142  128 CPTGALRLVD 137
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 12-165 3.86e-31

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 112.35  E-value: 3.86e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACKSWNQLPGIKTKNTGSYQNPPDLasaayNIIRyneVPSQENPVRwlfvsrrCMHCDDAGCMK 91
Cdd:cd10554    2 VIADPDKCIGCRTCEVACAAAHSGKGIFEAGTDGLPFLPRL-----RVVK---TGEVTAPVQ-------CRQCEDAPCAN 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  92 ICPSGALYRTaEGAVAFDRDKCIGCKLCVNACPFD----VPRYDAD--------GKVTKCHLCFDRiAAGmnPACVKTCP 159
Cdd:cd10554   67 VCPVGAISQE-DGVVQVDEERCIGCKLCVLACPFGaiemAPTTVPGvdwergprAVAVKCDLCAGR-EGG--PACVEACP 142


                 ....*.
gi 700405100 160 TGALKF 165
Cdd:cd10554  143 TKALTL 148
PRK14993 PRK14993
tetrathionate reductase subunit TtrB;
5-167 4.70e-29

tetrathionate reductase subunit TtrB;


Pssm-ID: 184955 [Multi-domain]  Cd Length: 244  Bit Score: 109.96  E-value: 4.70e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   5 NSNNRKAILVTPELCIGCRACQVACKSWNQLPGIKTKNTgsyqnppdlasaaynIIRYNEVPSQENPVRWLFVSRRCMHC 84
Cdd:PRK14993  39 SPRHRYAMLIDLRRCIGCQSCTVSCTIENQTPQGAFRTT---------------VNQYQVQREGSQEVTNVLLPRLCNHC 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  85 DDAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDADGKVT-KCHLCFDRIAAGMNPACVKTCPTGAL 163
Cdd:PRK14993 104 DNPPCVPVCPVQATFQREDGIVVVDNKRCVGCAYCVQACPYDARFINHETQTAdKCTFCVHRLEAGLLPACVESCVGGAR 183


                 ....
gi 700405100 164 KFGD 167
Cdd:PRK14993 184 IIGD 187
TH_beta_N cd10552
N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This ...
 17-178 8.46e-26

N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This family includes the beta subunit of pyrogallol-phloroglucinol transhydroxylase (TH), a cytoplasmic molybdenum (Mo) enzyme from anaerobic microorganisms like Pelobacter acidigallici and Desulfitobacterium hafniense which catalyzes the conversion of pyrogallol to phloroglucinol, an important building block of plant polymers. TH belongs to the DMSO reductase (DMSOR) family; it is a heterodimer consisting of a large alpha catalytic subunit and a small beta FeS subunit. The beta subunit has two domains with the N-terminal domain containing three [4Fe-4S] centers and a seven-stranded, mainly antiparallel beta-barrel domain. In the anaerobic bacterium Pelobacter acidigallici, gallic acid, pyrogallol, phloroglucinol, or phloroglucinol carboxylic acid are fermented to three molecules of acetate (plus CO2), and TH is the key enzyme in the fermentation pathway, which converts pyrogallol to phloroglucinol in the absence of O2.


Pssm-ID: 319874 [Multi-domain]  Cd Length: 186  Bit Score: 99.71  E-value: 8.46e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  17 ELCIGCRACQVACK---SWNQLPGiktkntgsYQNP-PDLASAAYNIIRynEVPSQENPVRWLFVSRRCMHCDDAGCMKI 92
Cdd:cd10552    6 AKCNGCYNCFLACKdehVGNDWPG--------YAAPqPRHGHFWMRILR--RERGQYPKVDVAYLPVPCNHCDNAPCIKA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  93 CPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDADGKV-TKCHLCFDRIAAGMN-PACVKTCPTGALKFGDREE 170
Cdd:cd10552   76 AKDGAVYKRDDGIVIIDPEKAKGQKQLVDACPYGAIYWNEELQVpQKCTFCAHLLDDGWKePRCVQACPTGALRFGKLED 155


                 ....*...
gi 700405100 171 LIGAAKKE 178
Cdd:cd10552  156 EEMAAKAA 163
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 12-176 1.12e-24

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 102.52  E-value: 1.12e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACkswnqlpgIKTKNTGSYQNPPDLASAAYNIIRYnevPSQENPVRwlfvsrrCMHCDDAGCMK 91
Cdd:PRK12769   5 IMANSQQCLGCHACEIAC--------VMAHNDEQHVLSQHHFHPRITVIKH---QQQRSAVT-------CHHCEDAPCAR 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  92 ICPSGALYRTAEGaVAFDRDKCIGCKLCVNACPFDV------PRYDADGKVT--KCHLCFDRIAAgmnPACVKTCPTGAL 163
Cdd:PRK12769  67 SCPNGAISHVDDS-IQVNQQKCIGCKSCVVACPFGTmqivltPVAAGKVKATahKCDLCAGRENG---PACVENCPADAL 142

                        170
                 ....*....|...
gi 700405100 164 KFGDREELIGAAK 176
Cdd:PRK12769 143 QLVTEQALSGMAK 155
NarH_like cd16365
beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several ...
 19-159 9.52e-23

beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several DMSO reductase superfamily, including nitrate reductase A, ethylbenzene dehydrogenase and selenate reductase. DMSO Reductase (DMSOR) family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. . The beta subunits of DMSOR contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system. Nitrate reductase A contains three subunits (the catalytic subunit NarG, the catalytic subunit NarH with four [Fe-S] clusters, and integral membrane subunit NarI) and often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Ethylbenzene dehydrogenase oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. Selenate reductase catalyzes reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor.


Pssm-ID: 319887 [Multi-domain]  Cd Length: 201  Bit Score: 92.26  E-value: 9.52e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  19 CIGCRACQVACKS-WNQLPG--------IKTKNTGSYqnPPDLAsaayniiryNEVPSQENPVRWLF-VSRRCMHCDDAG 88
Cdd:cd16365   12 CIGCQTCTVACKNaWTYRKGqeymwwnnVETKPGGGY--PQDWE---------VKTIDNGGNTRFFFyLQRLCNHCTNPA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 700405100  89 CMKICPSGALY-RTAEGAVAFDRDKCIGCKLCVNACPFDVPRYD-ADGKVTKCHLCFDRIAAGMNPACVKTCP 159
Cdd:cd16365   81 CLAACPRGAIYkREEDGIVLIDQKRCRGYRKCVEQCPYKKIYFNgLSRVSEKCIACYPRIEGGDPTRCMSACV 153
NarH_beta-like cd10557
beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes ...
 76-158 3.54e-19

beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes nitrate reductase A, a member of the DMSO reductase family. The respiratory nitrate reductase complex (NarGHI) from E. coli is a heterotrimer, with the catalytic subunit (NarG) with a molybdo-bis (molybdopterin guanine dinucleotide) cofactor and an [Fe-S] cluster, the electron transfer subunit (NarH) with four [Fe-S] clusters, and the integral membrane subunit (NarI) with two b-type hemes. Nitrate reductase A often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Electron transfer from formate to nitrate is coupled to proton translocation across the cytoplasmic membrane generating proton motive force by a redox loop mechanism. Demethylmenaquinol (DMKH2) has been shown to be a good substrate for NarGHI in nitrate respiration in E. coli.


Pssm-ID: 319879 [Multi-domain]  Cd Length: 363  Bit Score: 85.49  E-value: 3.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  76 FVSRRCMHCDDAGCMKICPSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYD-ADGKVTKCHLCFDRIAAGMNPA 153
Cdd:cd10557  174 YLPRICNHCLNPACVAACPSGAIYKREEdGIVLIDQDRCRGWRMCVSACPYKKVYYNwKTGKSEKCIFCYPRLEAGQPTV 253


                 ....*
gi 700405100 154 CVKTC 158
Cdd:cd10557  254 CSETC 258
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 19-167 3.88e-18

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 83.54  E-value: 3.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  19 CIGCRACQVAC------KSWNQ-----LPGIKTKNTGSYQNPPdlasaayniirynevpsqenpvrwlfvsrRCMHCDDA 87
Cdd:PRK12809  12 CIGCHACEIACavahnqENWPLshsdfRPRIHVVGKGQAANPV-----------------------------ACHHCNNA 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  88 GCMKICPSGALYrTAEGAVAFDRDKCIGCKLCVNACPFDVPRYdADGKVTKCHLCFDRIAAgmNPACVKTCPTGALKFGD 167
Cdd:PRK12809  63 PCVTACPVNALT-FQSDSVQLDEQKCIGCKRCAIACPFGVVEM-VDTIAQKCDLCNQRSSG--TQACIEVCPTQALRLMD 138
EBDH_beta cd10555
beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene ...
 19-159 4.51e-18

beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene dehydrogenase (EBDH, EC 1.17.99.2), a member of the DMSO reductase family. EBDH oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. It is a heterotrimer, with the alpha subunit containing the catalytic center with a molybdenum held by two molybdopterin-guanine dinucleotides, the beta subunit containing four iron-sulfur clusters (the electron transfer subunit) and the gamma subunit containing a methionine and a lysine as axial heme ligands. During catalysis, electrons produced by substrate oxidation are transferred to a heme in the gamma subunit and then presumably to a separate cytochrome involved in nitrate respiration.


Pssm-ID: 319877 [Multi-domain]  Cd Length: 316  Bit Score: 81.58  E-value: 4.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  19 CIGCRACQVACKS------------WNQL---PGI-----------KTKNTGSYQNPP-------------DLASAAYNI 59
Cdd:cd10555   14 CIGCQTCTVACKTlwtnrngreymyWNNVetqPGKgypknwekkggGFKDKGELKPGIiptledygvpweyNHEEELFEG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  60 IRYNEVPSQENPVRW------------------LFVSRRCMHCDDAGCMKICPSGALYRTAE-GAVAFDRDKCIGCKLCV 120
Cdd:cd10555   94 KGGRVRPSPKGDPTWgpnwdedqgageypnsyyFYLPRICNHCTNPACLAACPRKAIYKREEdGIVLVDQDRCRGYRYCV 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 700405100 121 NACPFDVPRYDA-DGKVTKCHLCFDRIAAGMNPACVKTCP 159
Cdd:cd10555  174 EACPYKKIYFNPvEQKSEKCIFCYPRIEKGVAPACARQCV 213
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 81-164 1.14e-17

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 76.96  E-value: 1.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  81 CMHCDDAGCMKICPSGALYRTAEGAVaFDRDKCIGCKLCVNACPFDVPRYDadgKVTKCHLCFDriaaGMNPACVKTCPT 160
Cdd:cd16367   57 CRHCVDPVCMIGCPTGAIHRDDGGEV-VISDACCGCGNCASACPYGAIQMV---RAVKCDLCAG----YAGPACVSACPT 128


                 ....
gi 700405100 161 GALK 164
Cdd:cd16367  129 GAAI 132
PRK09898 PRK09898
ferredoxin-like protein;
7-164 1.19e-17

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 78.72  E-value: 1.19e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   7 NNRKAILVTPEL-CIGCRACQVACKSWNQ------LPGIKTKNTGSYQNPPDLASAAYniirYNEVpsqenpvrwLFVSR 79
Cdd:PRK09898  55 NTPKGVLVTQRArCTGCHRCEISCTNFNDgsvgtfFSRIKIHRNYFFGDNGVGSGGGL----YGDL---------NYTAD 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  80 RCMHCDDAGCMKICPSGAL-YRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDA-DGKVTKCHLCfdriaagmnPACVKT 157
Cdd:PRK09898 122 TCRQCKEPQCMNVCPIGAItWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTeSKKSSKCVLC---------GECANA 192


                 ....*..
gi 700405100 158 CPTGALK 164
Cdd:PRK09898 193 CPTGALK 199
PRK10330 PRK10330
electron transport protein HydN;
12-171 1.23e-17

electron transport protein HydN;


Pssm-ID: 182382 [Multi-domain]  Cd Length: 181  Bit Score: 78.01  E-value: 1.23e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  12 ILVTPELCIGCRACQVACkswnqlpgiktknTGSYQNPPDLAS-AAYNIIRYNEVPSQENpvrwLFVSRRCMHCDDAGCM 90
Cdd:PRK10330   5 IIADASKCIGCRTCEVAC-------------VVSHQENQDCASlTPETFLPRIHVIKGVN----VSTATVCRQCEDAPCA 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  91 KICPSGALYRTaEGAVAFDRDKCIGCKLCVNACPFD--------VPRYDADG--------KVTKCHLCFDRIAAgmnPAC 154
Cdd:PRK10330  68 NVCPNGAISRD-KGFVHVMQERCIGCKTCVVACPYGamevvvrpVIRNSGAGlnvraekaEANKCDLCNHREDG---PAC 143

                        170
                 ....*....|....*..
gi 700405100 155 VKTCPTGALKFGDREEL 171
Cdd:PRK10330 144 MAACPTHALICVDRNKL 160
NarY COG1140
Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and ...
 79-158 1.24e-17

Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440755 [Multi-domain]  Cd Length: 485  Bit Score: 81.78  E-value: 1.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  79 RRCMHCDDAGCMKICPSGALYRTAE-GAVAFDRDKCIGCKLCVNACPFDVPRYD-ADGKVTKCHLCFDRIAAGMNPACVK 156
Cdd:COG1140  180 RICEHCLNPACVASCPSGAIYKREEdGIVLVDQDKCRGWRMCVSGCPYKKVYFNwKTGKAEKCIFCYPRIEAGQPTVCSE 259


                 ..
gi 700405100 157 TC 158
Cdd:COG1140  260 TC 261
SER_beta cd10556
Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate ...
 19-159 1.04e-16

Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate reductase (SER), a member of the DMSO reductase family. SER catalyzes the reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor. The enzyme comprises three subunits SerABC, forming a heterotrimer, with the catalytic component (alpha-subunit), iron-sulfur protein (beta-subunit) and monomeric b-type heme-containing gamma subunit. Beta subunit contains coordinating one [3Fe-4S] cluster and three [4Fe-4S] clusters and functions as electron carrier.


Pssm-ID: 319878 [Multi-domain]  Cd Length: 287  Bit Score: 77.50  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  19 CIGCRACQVACKS------------WN--------------------QLPGIKTKNTGSYQNP--PDLASAAYNIIRY-- 62
Cdd:cd10556   21 CIACQTCTMACKStwtsgkgqeymwWNnvetkpyggyplgwdvrlldEEGGQTWAEGGVYEGKtiFEAAAAGEQVLGYrp 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  63 ------------NEVPSQENP---------VRWLF-VSRRCMHCDDAGCMKICPSGALY-RTAEGAVAFDRDKCIGCKLC 119
Cdd:cd10556  101 ededwrypnigeDEVNGERTPdtgsslpphPIWFFyLPRICNHCTYPACLAACPRKAIYkREEDGIVLIDQERCRGYREC 180

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 700405100 120 VNACPFDVPRYDADGKVT-KCHLCFDRIAAGMNPACVKTCP 159
Cdd:cd10556  181 VEACPYKKPMYNPTTRVSeKCIGCYPRIEEGDQTQCVSACI 221
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 16-164 2.04e-16

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 73.14  E-value: 2.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  16 PELCIGCRACQVAC-KSWNqlpgiKTKNtgsyqnpPDLASaayniIRYNEVPSQENPVrwlfvsrRCMHCDDagCMKICP 94
Cdd:cd16372    7 PEKCIGCLQCEEACsKTFF-----KEED-------REKSC-----IRITETEGGYAIN-------VCNQCGE--CIDVCP 60

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700405100  95 SGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDADGKV-TKChlcfdrIAAGmnpACVKTCPTGALK 164
Cdd:cd16372   61 TGAITRDANGVVMINKKLCVGCLMCVGFCPEGAMFKHEDYPEpFKC------IACG---ICVKACPTGALE 122
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 16-165 1.94e-15

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 70.76  E-value: 1.94e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  16 PELCIGCRACQVACKSWNQlpgiktkNTGSyqnppdLASAAYNIIRYNEVPSQenpvrwlFVSRRCMHCDDAGCMKICPS 95
Cdd:cd16370    8 MERCIGCYSCMLACSRRVH-------KSAS------LSKSAIRVRTRGGLEGG-------FTVVVCRACEDPPCAEACPT 67

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700405100  96 GALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDAD-GKVTKCHLCfdriaagmnPACVKTCPTGALKF 165
Cdd:cd16370   68 GALEPRKGGGVVLDKEKCIGCGNCVKACIVGAIFWDEEtNKPIICIHC---------GYCARYCPHDVLAM 129
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
89-170 7.53e-11

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 60.85  E-value: 7.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  89 CMKICPSGALY----RTAEGAVAFDRDKCIGCKLCVNACPFDVPryDADGKVT--KCHLCFDriaagmnpaCVKTCPTGA 162
Cdd:COG0348  184 CRYLCPYGAFQgllsDLSTLRVRYDRGDCIDCGLCVKVCPMGID--IRKGEINqsECINCGR---------CIDACPKDA 252


                 ....*...
gi 700405100 163 LKFGDREE 170
Cdd:COG0348  253 IRFSSRGE 260
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
100-174 8.77e-11

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 61.41  E-value: 8.77e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100 100 RTAEGAVA-FDRDKCIGCKLCVNACPFDVPRYDADGKV----TKCHLCfdriaaGmnpACVKTCPTGALKFGD-REELIG 173
Cdd:COG1148  484 LGVEPSVAeVDPEKCTGCGRCVEVCPYGAISIDEKGVAevnpALCKGC------G---TCAAACPSGAISLKGfTDDQIL 554


                 .
gi 700405100 174 A 174
Cdd:COG1148  555 A 555
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 106-170 2.04e-09

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 52.81  E-value: 2.04e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 700405100 106 VAFDRDKCIGCKLCVNACPFDVPRYDADGKVT----KCHLCFdriaagmnpACVKTCPTGALKFGDREE 170
Cdd:COG1149    6 PVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVvdpdLCTGCG---------ACVGVCPTGAITLEEREA 65
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 80-170 4.27e-09

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 53.55  E-value: 4.27e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  80 RCMHCddAGCMKICPSGALYRTAEGAVA----FDRDKCIGCKLCVNACPFDVPRYDADGKVTKCH---------LCfdrI 146
Cdd:cd10549    7 KCIGC--GICVKACPTDAIELGPNGAIArgpeIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKekeaeideeKC---I 81

                         90       100
                 ....*....|....*....|....
gi 700405100 147 AAGMnpaCVKTCPTGALKFGDREE 170
Cdd:cd10549   82 GCGL---CVKVCPVDAITLEDELE 102
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 106-170 1.05e-08

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 50.48  E-value: 1.05e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700405100 106 VAFDRDKCIGCKLCVNACPFDVPRYDADGKVT------KCHLCFdriaagmnpACVKTCPTGALKFGDREE 170
Cdd:COG1146    3 PVIDTDKCIGCGACVEVCPVDVLELDEEGKKAlvinpeECIGCG---------ACELVCPVGAITVEDDEP 64
Form-deh_trans pfam09163
Formate dehydrogenase N, transmembrane; Members of this family are predominantly found in the ...
 213-255 1.52e-08

Formate dehydrogenase N, transmembrane; Members of this family are predominantly found in the beta subunit of formate dehydrogenase, and consist of a single transmembrane helix. They act as a transmembrane anchor, and allow for conduction of electrons within the protein.


Pssm-ID: 430440  Cd Length: 43  Bit Score: 49.54  E-value: 1.52e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 700405100  213 IPSSVNFWHTYLKPLSVIGLGGVVAAAAIHYLAIGPHKDNNEE 255
Cdd:pfam09163   1 ISPSVELWKGVLKPLGAAGMGAAALAGFFHYITVGPNKVEEEE 43
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 104-167 3.10e-08

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 50.99  E-value: 3.10e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 700405100 104 GAVAFDRDKCIGCKLCVNACPFDVPRYDADGK-----VTKCHLCfdriaagmnPACVKTCPTGALKFGD 167
Cdd:PRK08348  35 GKILYDVDKCVGCRMCVTVCPAGVFVYLPEIRkvalwTGRCVFC---------GQCVDVCPTGALQMSD 94
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 89-165 3.72e-08

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 50.86  E-value: 3.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  89 CMKICPSGALYRTAEGAVAF--------DRDKCIGCKLCVNACPFDVPRYDADGKVT----KCHLCfdriaagmnPACVK 156
Cdd:cd10549   48 CVEVCPTGAIELTPEGKEYVpkekeaeiDEEKCIGCGLCVKVCPVDAITLEDELEIVidkeKCIGC---------GICAE 118


                 ....*....
gi 700405100 157 TCPTGALKF 165
Cdd:cd10549  119 VCPVNAIKL 127
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 80-126 4.03e-08

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 48.96  E-value: 4.03e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100  80 RCMHCDDagCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFD 126
Cdd:COG1149   12 KCIGCGL--CVEVCPEGAIKLDDGGAPVVDPDLCTGCGACVGVCPTG 56
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
79-164 4.34e-08

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 53.11  E-value: 4.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  79 RRCMHCDDAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDVPRYDaDGKV----TKCHLCfdriaaGMnpaC 154
Cdd:COG4624   59 CCCCRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAIKVD-DGKAeideEKCISC------GQ---C 128

                         90
                 ....*....|
gi 700405100 155 VKTCPTGALK 164
Cdd:COG4624  129 VAVCPFGAIT 138
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 108-178 5.31e-08

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 50.47  E-value: 5.31e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 700405100 108 FDRDKCIGCKLCVNACPFDVPRYDADGKV--------TKCHLCFdriaagmnpACVKTCPTGALKFGDREELIGAAKKE 178
Cdd:cd10549    3 YDPEKCIGCGICVKACPTDAIELGPNGAIargpeideDKCVFCG---------ACVEVCPTGAIELTPEGKEYVPKEKE 72
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
80-126 8.37e-08

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 48.19  E-value: 8.37e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100  80 RCMHCDDagCMKICPSGALYRTaEGAVAFDRDKCIGCKLCVNACPFD 126
Cdd:COG2768   12 KCIGCGA--CVKVCPVGAISIE-DGKAVIDPEKCIGCGACIEVCPVG 55
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 80-126 1.97e-07

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 47.01  E-value: 1.97e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 700405100  80 RCMHCDDagCMKICPSGALYRTAEGAVAF--DRDKCIGCKLCVNACPFD 126
Cdd:COG1146    9 KCIGCGA--CVEVCPVDVLELDEEGKKALviNPEECIGCGACELVCPVG 55
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 78-124 2.97e-07

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 51.03  E-value: 2.97e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 700405100  78 SRRCMHC----DDAGCMKICPSGALYRTAEGA-VAFDRDKCIGCKLCVNACP 124
Cdd:PRK12771 503 AARCLSCgncfECDNCYGACPQDAIIKLGPGRrYHFDYDKCTGCHICADVCP 554
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 110-169 3.52e-07

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 46.28  E-value: 3.52e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700405100 110 RDKCIGCKLCVNACPFDVPRYDADGKVTKCHLCFDR-IAAGMnpaCVKTCPTGALKFGDRE 169
Cdd:COG1143    1 EDKCIGCGLCVRVCPVDAITIEDGEPGKVYVIDPDKcIGCGL---CVEVCPTGAISMTPFE 58
PRK13795 PRK13795
hypothetical protein; Provisional
 79-124 3.74e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 50.76  E-value: 3.74e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 700405100  79 RRCMHCDDAG-CMKICPSGALYRTAEGA-VAFDRDKCIGCKLCVNACP 124
Cdd:PRK13795 578 RRAAECVGCGvCVGACPTGAIRIEEGKRkISVDEEKCIHCGKCTEVCP 625
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 80-126 4.50e-07

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 46.19  E-value: 4.50e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100  80 RCMHCDDagCMKICPSGALYRtAEGAVAFDRDKCIGCKLCVNACPFD 126
Cdd:COG4231   23 KCTGCGA--CVKVCPADAIEE-GDGKAVIDPDLCIGCGSCVQVCPVD 66
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 80-126 4.55e-07

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 45.89  E-value: 4.55e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 700405100  80 RCMHCDDagCMKICPSGALYRTAEGAVA---FDRDKCIGCKLCVNACPFD 126
Cdd:COG1143    3 KCIGCGL--CVRVCPVDAITIEDGEPGKvyvIDPDKCIGCGLCVEVCPTG 50
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 80-126 4.78e-07

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 46.58  E-value: 4.78e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100  80 RCMHCDDagCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFD 126
Cdd:COG1144   31 KCIGCGL--CWIVCPDGAIRVDDGKYYGIDYDYCKGCGICAEVCPVK 75
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 79-127 5.54e-07

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 47.39  E-value: 5.54e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 700405100  79 RRCMHCDDagCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDV 127
Cdd:cd10549   78 EKCIGCGL--CVKVCPVDAITLEDELEIVIDKEKCIGCGICAEVCPVNA 124
Fer COG1141
Ferredoxin [Energy production and conversion];
106-164 6.22e-07

Ferredoxin [Energy production and conversion];


Pssm-ID: 440756 [Multi-domain]  Cd Length: 63  Bit Score: 45.64  E-value: 6.22e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 700405100 106 VAFDRDKCIGCKLCVNACPfDVPRYDADGKVtkcHLCFDRIAAGMNPAC---VKTCPTGALK 164
Cdd:COG1141    3 VTVDRDTCIGCGLCVALAP-EVFELDDDGKA---VVLDEEVPEELEEDVreaADACPVGAIT 60
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 80-127 6.69e-07

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 45.81  E-value: 6.69e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 700405100  80 RCMHCDDagCMKICPSGALyRTAEGAVAFDRDKCIGCKLCVNACPFDV 127
Cdd:COG2221   16 KCIGCGL--CVAVCPTGAI-SLDDGKLVIDEEKCIGCGACIRVCPTGA 60
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 109-170 7.26e-07

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 45.80  E-value: 7.26e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700405100 109 DRDKCIGCKLCVNACPFDVpRYDADGKV----TKCHLCFdriaagmnpACVKTCPTGALKFGDREE 170
Cdd:COG4231   20 DEDKCTGCGACVKVCPADA-IEEGDGKAvidpDLCIGCG---------SCVQVCPVDAIKLEKRVP 75
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
109-170 9.70e-07

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 45.49  E-value: 9.70e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 700405100 109 DRDKCIGCKLCVNACPFDVPRYDADGKVT---KCHLCfdriaagmnPACVKTCPTGALKFGDREE 170
Cdd:COG2768    9 DEEKCIGCGACVKVCPVGAISIEDGKAVIdpeKCIGC---------GACIEVCPVGAIKIEWEED 64
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
107-172 1.50e-06

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 46.80  E-value: 1.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100 107 AFDRD-----KCIGCKLCVNACPFDVPRYDA----DGK---------VTKCHLCfdriaaGMnpaCVKTCPTGALKFG-- 166
Cdd:PRK05888  49 ALRRDpngeeRCIACKLCAAICPADAITIEAaereDGRrrttrydinFGRCIFC------GF---CEEACPTDAIVETpd 119

                         90
                 ....*....|..
gi 700405100 167 ------DREELI 172
Cdd:PRK05888 120 felateTREELI 131
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
80-124 1.65e-06

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 45.71  E-value: 1.65e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 700405100  80 RCMHCddAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACP 124
Cdd:PRK09623  52 KCVKC--YICWKFCPEPAIYIKEDGYVAIDYDYCKGCGICANECP 94
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 108-164 2.23e-06

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 44.27  E-value: 2.23e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700405100 108 FDRDKCIGCKLCVNACPFDVPRYDaDGKVT----KCHLCFdriaagmnpACVKTCPTGALK 164
Cdd:COG2221   12 IDEEKCIGCGLCVAVCPTGAISLD-DGKLVideeKCIGCG---------ACIRVCPTGAIK 62
NapF COG1145
Ferredoxin [Energy production and conversion];
49-127 2.97e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 47.02  E-value: 2.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  49 PPDLASAAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDagCMKICPSGALYRTAEGAVA-FDRDKCIGCKLCVNACPFDV 127
Cdd:COG1145  152 PVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGL--CVKVCPTGAIRLKDGKPQIvVDPDKCIGCGACVKVCPVGA 229
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 97-189 3.38e-06

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 45.10  E-value: 3.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100   97 ALYRTAEGavafdRDKCIGCKLCVNACPFD-VPRYDADGKVTKCHLCFDRIAAG---MNPACVKTCPTGALKFGDREELI 172
Cdd:TIGR01971  34 VLTRDPNG-----EEKCIGCTLCAAVCPADaIRVVPAEGEDGKRRLKFYEINFGrciFCGLCEEACPTDAIVLTPEFELA 108

                          90
                  ....*....|....*..
gi 700405100  173 GAAKKEgfaTIYGEQDL 189
Cdd:TIGR01971 109 TYTRSD---LVYGKEDL 122
NapF COG1145
Ferredoxin [Energy production and conversion];
103-169 5.38e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 46.25  E-value: 5.38e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 700405100 103 EGAVAFDRDKCIGCKLCVNACPFDVPRYDADGKVT-----KCHLCfdriaagmnPACVKTCPTGALKFGDRE 169
Cdd:COG1145  174 KAKAVIDAEKCIGCGLCVKVCPTGAIRLKDGKPQIvvdpdKCIGC---------GACVKVCPVGAISLEPKE 236
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 108-170 5.87e-06

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 43.50  E-value: 5.87e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 700405100 108 FDRDKCIGCKLCVNACPFDVPRYDADGKVT----KCHLCFdriaagmnpACVKTCPTGALKFGDREE 170
Cdd:COG1144   27 VDEDKCIGCGLCWIVCPDGAIRVDDGKYYGidydYCKGCG---------ICAEVCPVKAIEMVPEEK 84
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 76-126 6.13e-06

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 43.86  E-value: 6.13e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 700405100  76 FVSRRCMHCddAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFD 126
Cdd:PRK09624  48 FNRDKCVRC--YLCYIYCPEPAIYLDEEGYPVFDYDYCKGCGICANECPTK 96
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 81-127 7.31e-06

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 46.14  E-value: 7.31e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100  81 CMHCDDagCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPFDV 127
Cdd:COG2878  139 CIGCGD--CIKACPFDAIVGAAKGMHTVDEDKCTGCGLCVEACPVDC 183
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 81-127 1.67e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 41.36  E-value: 1.67e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 700405100   81 CMHCDDagCMKICPSGALYRTAEG------AVAFDRDKCIGCKLCVNACPFDV 127
Cdd:pfam12838   1 CIGCGA--CVAACPVGAITLDEVGekkgtkTVVIDPERCVGCGACVAVCPTGA 51
FeFe_hydrog_B1 TIGR04105
[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.
 8-125 1.86e-05

[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.


Pssm-ID: 274983 [Multi-domain]  Cd Length: 462  Bit Score: 45.28  E-value: 1.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100    8 NRKAIlVTPELCIGCRACQVACkswnqlpgiktkntgsyqnpPdlasaaYNIIRYNEVPsqenpvrwlfvsrrcmhcdda 87
Cdd:TIGR04105 134 NGRAY-IDQEKCIECGKCKKAC--------------------P------YNAIVEIERP--------------------- 165

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 700405100   88 gCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACPF 125
Cdd:TIGR04105 166 -CEKACPVGAISSDEDGRAVIDYDKCISCGACMVACPF 202
napG PRK09476
quinol dehydrogenase periplasmic component; Provisional
 94-163 3.27e-05

quinol dehydrogenase periplasmic component; Provisional


Pssm-ID: 236534 [Multi-domain]  Cd Length: 254  Bit Score: 43.85  E-value: 3.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  94 PSGALyrtAEGAVAfdrDKCIGCKLCVNACPFDVPRYD--ADGKVT----------KCHLCFDrIaagmnpACVKTCPTG 161
Cdd:PRK09476  48 PPGAL---NENDFL---SACIRCGLCVQACPYDTLKLAtlASGLSAgtpyfvardiPCEMCED-I------PCVKACPSG 114


                 ..
gi 700405100 162 AL 163
Cdd:PRK09476 115 AL 116
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 73-124 3.33e-05

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 40.70  E-value: 3.33e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 700405100   73 RWLFVSRRCMHCddAGCMKICPSGA------LYRTAEGAVAFDRDKCIGCKLCVNACP 124
Cdd:pfam13237   1 KVVIDPDKCIGC--GRCTAACPAGLtrvgaiVERLEGEAVRIGVWKCIGCGACVEACP 56
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 89-126 4.21e-05

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 44.39  E-value: 4.21e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100  89 CMKICPsgaLYRTAEGAVAFDRDK---------CIGCKLCVNACPFD 126
Cdd:COG1245   21 CIKYCP---VNRTGKEAIEIDEDDgkpviseelCIGCGICVKKCPFD 64
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
89-126 6.32e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 43.64  E-value: 6.32e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 700405100  89 CMKICPsgaLYRTAEGAVAFDRDK---------CIGCKLCVNACPFD 126
Cdd:PRK13409  21 CIKYCP---VVRTGEETIEIDEDDgkpviseelCIGCGICVKKCPFD 64
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 109-172 1.06e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 41.14  E-value: 1.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 700405100 109 DRDKCIGCKLCVNACP---FDVPRYDADGK-------VTKCHLCfdriaagMNPACVKTCPTGALKFGDREELI 172
Cdd:cd16367   17 DLDRCIRCDNCEKACAdthDGHSRLDRNGLrfgnllvPTACRHC-------VDPVCMIGCPTGAIHRDDGGEVV 83
ndhI CHL00014
NADH dehydrogenase subunit I
 104-171 1.38e-04

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 41.28  E-value: 1.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100 104 GAVAFDRDKCIGCKLCVNACPFDVP----RYDADGKVTK----------CHLCFDriaagmnpaCVKTCPTGALKFGDRE 169
Cdd:CHL00014  52 GRIHFEFDKCIACEVCVRVCPIDLPvvdwKLETDIRKKRllnysidfgvCIFCGN---------CVEYCPTNCLSMTEEY 122


                 ..
gi 700405100 170 EL 171
Cdd:CHL00014 123 EL 124
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 81-126 1.43e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 41.09  E-value: 1.43e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 700405100  81 CMHCDDAgCMKICPSGALYRTAE-------GAVAFDRDKCI------GCKLCVNACPFD 126
Cdd:cd16373   55 CDLCCDA-CVEVCPTGALRPLDLeeqkvkmGVAVIDKDRCLawqggtDCGVCVEACPTE 112
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 112-164 1.56e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 41.09  E-value: 1.56e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700405100 112 KCIGCKLCVNACPFDV--PRYDADG-----------KVTKCHLCFDriaagmnpACVKTCPTGALK 164
Cdd:cd16373   15 LCIRCGLCVEACPTGViqPAGLEDGleggrtpyldpREGPCDLCCD--------ACVEVCPTGALR 72
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 105-159 1.89e-04

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 38.39  E-value: 1.89e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 700405100  105 AVAFDRDKCIGCKLCVNACPFDVPRYDAD----------GKVTKCHLCFdriaagmnpACVKTCP 159
Cdd:pfam13237   1 KVVIDPDKCIGCGRCTAACPAGLTRVGAIverlegeavrIGVWKCIGCG---------ACVEACP 56
napG PRK09476
quinol dehydrogenase periplasmic component; Provisional
 76-125 2.00e-04

quinol dehydrogenase periplasmic component; Provisional


Pssm-ID: 236534 [Multi-domain]  Cd Length: 254  Bit Score: 41.53  E-value: 2.00e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 700405100  76 FVSRR--CMHCDDAGCMKICPSGALYRTAEG--------AVAFDRDKCIG-----CKLCVNACPF 125
Cdd:PRK09476  92 FVARDipCEMCEDIPCVKACPSGALDRELVDiddarmglAVLVDQENCLNfqglrCDVCYRVCPL 156
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
81-164 3.62e-04

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 41.07  E-value: 3.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  81 CMHCDDagCMKICPSGALyRTAEGAVAFDRDKCIGCKLCVNACPFDV----PRYDA---------DGKVTK--CHL-Cfd 144
Cdd:PRK07118 141 CLGLGS--CVAACPFDAI-HIENGLPVVDEDKCTGCGACVKACPRNVieliPKSARvfvacnskdKGKAVKkvCEVgC-- 215

                         90       100
                 ....*....|....*....|
gi 700405100 145 rIAAGMnpaCVKTCPTGALK 164
Cdd:PRK07118 216 -IGCGK---CVKACPAGAIT 231
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
65-138 6.44e-04

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 40.05  E-value: 6.44e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 700405100  65 VPSQENPVRWLFVSRRCMHCDDagCMKICPSGALYRTAEgavaFDRDKCIGCKLCVNACPFDVPRYDADGKVTK 138
Cdd:COG0348  196 LLSDLSTLRVRYDRGDCIDCGL--CVKVCPMGIDIRKGE----INQSECINCGRCIDACPKDAIRFSSRGEKTR 263
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 111-170 6.69e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.84  E-value: 6.69e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 700405100 111 DKCIGCKLCVNACP-----FDvprydaDGKV---TKCHLCFdriaagmnpACVKTCPTGALKFGDREE 170
Cdd:NF038196 185 DKCIGCGICAKVCPvnnieME------DGKPvwgHNCTHCL---------ACIHRCPKEAIEYGKKTK 237
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 106-129 7.97e-04

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 36.07  E-value: 7.97e-04
                          10        20
                  ....*....|....*....|....
gi 700405100  106 VAFDRDKCIGCKLCVNACPFDVPR 129
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGAIT 24
Fer4_9 pfam13187
4Fe-4S dicluster domain;
112-163 8.83e-04

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 36.38  E-value: 8.83e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 700405100  112 KCIGCKLCVNACPFDVPRYDADGKV-------TKCHLCfdriaagmnPACVKTCPTGAL 163
Cdd:pfam13187   1 KCTGCGACVAACPAGAIVPDLVGQTirgdiagLACIGC---------GACVDACPRGAI 50
YjdI COG3592
Uncharacterized Fe-S cluster protein YjdI [Function unknown];
99-165 9.17e-04

Uncharacterized Fe-S cluster protein YjdI [Function unknown];


Pssm-ID: 442811 [Multi-domain]  Cd Length: 71  Bit Score: 36.81  E-value: 9.17e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 700405100  99 YRTAEGAVAFDRDKCIGCKLCVNACP--FDV---PRYDADGKVTkchlcfDRIAagmnpACVKTCPTGALKF 165
Cdd:COG3592    8 YSGEEITVVWDPELCIHSGNCVKGLPevFDPkrkPWINPDNAST------EEII-----EQIDRCPSGALSY 68
Fer4_15 pfam13459
4Fe-4S single cluster domain;
106-163 1.12e-03

4Fe-4S single cluster domain;


Pssm-ID: 404359 [Multi-domain]  Cd Length: 66  Bit Score: 36.57  E-value: 1.12e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700405100  106 VAFDRDKCIGCKLCVNACPfDVPRYDADGKVTkCHLCFDRIAAGMNP----ACVK----TCPTGAL 163
Cdd:pfam13459   1 VEVDRDRCIGCGLCVALDP-ELFELDDDGKAS-VLLDDGEIGEGEVPdddeEAAQeaarACPVDAI 64
Fer4_6 pfam12837
4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...
 106-128 1.14e-03

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 432822 [Multi-domain]  Cd Length: 24  Bit Score: 35.67  E-value: 1.14e-03
                          10        20
                  ....*....|....*....|...
gi 700405100  106 VAFDRDKCIGCKLCVNACPFDVP 128
Cdd:pfam12837   2 VEVDPDKCIGCGRCVVVCPYGAI 24
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 19-97 1.31e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 35.97  E-value: 1.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 700405100   19 CIGCRACQVACkswnqlpgiktkntgsyqnppdlasaAYNIIRYNEVPSQENPVRWLFVSRRCMHCDDagCMKICPSGA 97
Cdd:pfam12838   1 CIGCGACVAAC--------------------------PVGAITLDEVGEKKGTKTVVIDPERCVGCGA--CVAVCPTGA 51
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 113-162 1.71e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 35.58  E-value: 1.71e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  113 CIGCKLCVNACPFDV----PRYDADGKVT------KCHLCfdriaagmnPACVKTCPTGA 162
Cdd:pfam12838   1 CIGCGACVAACPVGAitldEVGEKKGTKTvvidpeRCVGC---------GACVAVCPTGA 51
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 109-195 1.75e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 38.91  E-value: 1.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100 109 DRDKCIGCKLCVNACPFDVPRYDADGKVTK---CHLCfdriaagmnPACVKTCPTGALKFGDREE-LIGAAKKEGFATIY 184
Cdd:cd03110   62 DQEKCIRCGNCERVCKFGAILEFFQKLIVDeslCEGC---------GACVIICPRGAIYLKDRDTgKIFISSSDGGPLVH 132

                         90
                 ....*....|.
gi 700405100 185 GEQDLGGLGSV 195
Cdd:cd03110  133 GRLNIGEENSG 143
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 78-124 1.78e-03

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 36.85  E-value: 1.78e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 700405100   78 SRRCMHCDDagCMKICPSGALYRTAEG--AVAFDRDKCIGCKLCVNACP 124
Cdd:TIGR00402  33 SAVCTRCGE--CASACENNILQLGQQGqpTVEFDNAECDFCGKCAEACP 79
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 109-161 2.03e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 38.44  E-value: 2.03e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 700405100 109 DRDKCIGCKLCVNACPFD--------VPRYDADgkvtKCHLCfdriaagmnPACVKTCPTG 161
Cdd:COG2878  135 CEYGCIGCGDCIKACPFDaivgaakgMHTVDED----KCTGC---------GLCVEACPVD 182
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 80-124 2.31e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 37.62  E-value: 2.31e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 700405100  80 RCMHCDDAgcmkiCPSGALYRTAEGAVAF---DRDKCIGCKLCVNACP 124
Cdd:cd16373  101 DCGVCVEA-----CPTEAIAIVLEDDVLRpvvDEDKCVGCGLCEYVCP 143
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 111-164 3.24e-03

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 36.84  E-value: 3.24e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100 111 DKCIGCKLCVNACPFDVPRYDADGKVT------KCHLCFdriaagmnpACVKTCPTGALK 164
Cdd:cd10564   13 DLCTRCGDCVEACPEGIIVRGDGGFPEldfsrgECTFCG---------ACAEACPEGALD 63
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
89-163 3.85e-03

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 37.99  E-value: 3.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  89 CMKICPSGALYRTAEGAVAF----DRDK-----------CIGCKLCVNACPFDVPRYDADGKV---TKCHLCfdriaagm 150
Cdd:PRK07118 176 CVKACPRNVIELIPKSARVFvacnSKDKgkavkkvcevgCIGCGKCVKACPAGAITMENNLAVidqEKCTSC-------- 247

                         90
                 ....*....|...
gi 700405100 151 nPACVKTCPTGAL 163
Cdd:PRK07118 248 -GKCVEKCPTKAI 259
Fer4_2 pfam12797
4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...
 104-125 4.30e-03

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 463711 [Multi-domain]  Cd Length: 22  Bit Score: 33.91  E-value: 4.30e-03
                          10        20
                  ....*....|....*....|..
gi 700405100  104 GAVAFDRDKCIGCKLCVNACPF 125
Cdd:pfam12797   1 WKPLIDADKCIGCGACVSACPA 22
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
80-124 4.36e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 37.92  E-value: 4.36e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 700405100  80 RCMHCddAGCMKICPSGALYRTAEGAVAFDRDKCIGCKLCVNACP 124
Cdd:COG1148  497 KCTGC--GRCVEVCPYGAISIDEKGVAEVNPALCKGCGTCAAACP 539
PRK06991 PRK06991
electron transport complex subunit RsxB;
105-126 5.81e-03

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 37.47  E-value: 5.81e-03
                         10        20
                 ....*....|....*....|...
gi 700405100 105 AVAF-DRDKCIGCKLCVNACPFD 126
Cdd:PRK06991  78 AVAViDEQLCIGCTLCMQACPVD 100
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 15-116 7.50e-03

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 36.55  E-value: 7.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700405100  15 TPELCIGCRACQVACKSwNQLPgIKTkntgsyqnppDLASaayniirynevpsqeNPVRWLFVSRRCMHCddAGCMKICP 94
Cdd:PRK12387  36 NPQQCIGCAACVNACPS-NALT-VET----------DLAT---------------GELAWEFNLGRCIFC--GRCEEVCP 86

                         90       100       110
                 ....*....|....*....|....*....|....
gi 700405100  95 SGA--LYRTAEGAVA----------FDRDKCIGC 116
Cdd:PRK12387  87 TAAikLSQEFELAVWkkedllqqseFALCNCRVC 120
Fer4_13 pfam13370
4Fe-4S single cluster domain of Ferredoxin I; Fer4_13 is a ferredoxin I from sulfate-reducing ...
 109-135 9.69e-03

4Fe-4S single cluster domain of Ferredoxin I; Fer4_13 is a ferredoxin I from sulfate-reducing bacteria. Chemical sequence analysis suggests that this characteriztic [4Fe-4S] cluster sulfur environment is widely distributed among ferredoxins.


Pssm-ID: 433153 [Multi-domain]  Cd Length: 58  Bit Score: 33.82  E-value: 9.69e-03
                          10        20
                  ....*....|....*....|....*..
gi 700405100  109 DRDKCIGCKLCVNACPfDVPRYDADGK 135
Cdd:pfam13370   2 DEDTCIDCGTCRELAP-EVFKYDDDGG 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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