|
Name |
Accession |
Description |
Interval |
E-value |
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
248-534 |
1.61e-58 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 198.48 E-value: 1.61e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 248 DKQEIKQLNLSLEEKVNQRTIALREANQELLSTLERMHQYQTQIVENEKMASLGQMVAGVAHEVNTPIGLGITGSTLLRD 327
Cdd:COG4191 90 LEALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGNAELLRR 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 328 KLADIQQSfddkkltsshlkrfiDEGIENLDLIYRNLNRAADLISNFKKVAvIQDDGVNTYINVHKLISDVLTSIQSELL 407
Cdd:COG4191 170 RLEDEPDP---------------EELREALERILEGAERAAEIVRSLRAFS-RRDEEEREPVDLNELIDEALELLRPRLK 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 408 PKKPVVTINCPTDL-AIHSKSEPLQQVFQQLLMNSvIHGFIGKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFD 486
Cdd:COG4191 234 ARGIEVELDLPPDLpPVLGDPGQLEQVLLNLLINA-IDAMEEGEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFE 312
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 743333863 487 PFVTSKRGQGASGLGMHLVYNLVTQaLGGRVMFDLEEKRGARFIITIP 534
Cdd:COG4191 313 PFFTTKPVGKGTGLGLSISYGIVEK-HGGRIEVESEPGGGTTFTITLP 359
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
167-534 |
3.33e-38 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 145.10 E-value: 3.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 167 ILIDVLLTLLILAVVYFIAIKVQRRIAKPIEQLSVLLQDVSKNhNYDARAPVTDVKEISALSNSLNIM---LTRTKKQLE 243
Cdd:COG5000 8 LLLLLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAG-DLSVRLPVTGDDEIGELARAFNRMtdqLKEQREELE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 244 RHEKDKQEI-------------------------KQLNLSLEEKVNQR--TIALREANQELLSTLERMHQYQ-------- 288
Cdd:COG5000 87 ERRRYLETIlenlpagvivldadgritlanpaaeRLLGIPLEELIGKPleELLPELDLAELLREALERGWQEeieltrdg 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 289 -----------------------TQIVENEKMASLGQMVAGVAHEVNTPIGlGITGST-LLRDKLADIQQSFDDKkltss 344
Cdd:COG5000 167 rrtllvrasplrddgyvivfddiTELLRAERLAAWGELARRIAHEIKNPLT-PIQLSAeRLRRKLADKLEEDRED----- 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 345 hLKRFidegienLDLIYRNLNRAADLISNFKKVAVIQDDgVNTYINVHKLISDVLTSIQSELLPKKPVVTINCPTDLA-I 423
Cdd:COG5000 241 -LERA-------LDTIIRQVDRLKRIVDEFLDFARLPEP-QLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPeV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 424 HSKSEPLQQVFQQLLMNSV--IhgfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRgQGaSGLG 501
Cdd:COG5000 312 LADRDQLEQVLINLLKNAIeaI-----EEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKP-KG-TGLG 384
|
410 420 430
....*....|....*....|....*....|...
gi 743333863 502 MHLVYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:COG5000 385 LAIVKKIV-EEHGGTIELESRPGGGTTFTIRLP 416
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
281-534 |
1.11e-31 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 125.34 E-value: 1.11e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 281 LERMHQYQTQIVENEKMASLGQMVAGVAHEVNTPIGlGITGST-LLRDKLADiqqsfddkkltsshlkrfiDEGIENLDL 359
Cdd:COG3852 116 ITERKRLERELRRAEKLAAVGELAAGLAHEIRNPLT-GIRGAAqLLERELPD-------------------DELREYTQL 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 360 IYRNLNRAADLISNFKKVAViQDDGVNTYINVHKLISDVLTSIQSELlPKKPVVTINCPTDL-AIHSKSEPLQQVFQQLL 438
Cdd:COG3852 176 IIEEADRLNNLVDRLLSFSR-PRPPEREPVNLHEVLERVLELLRAEA-PKNIRIVRDYDPSLpEVLGDPDQLIQVLLNLV 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 439 MNSV--------IHgFIGKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrGQGaSGLGMHLVYNLVT 510
Cdd:COG3852 254 RNAAeampeggtIT-IRTRVERQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTK-EKG-TGLGLAIVQKIVE 330
|
250 260
....*....|....*....|....
gi 743333863 511 QaLGGRVMFDLEEKRGARFIITIP 534
Cdd:COG3852 331 Q-HGGTIEVESEPGKGTTFRIYLP 353
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
268-534 |
1.46e-30 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 121.55 E-value: 1.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 268 IALREANQELLSTLERMHQYQTQIVENEKMASLGQMVAGVAHEVNTPIGLGITGSTLLRDKLADIQQsfddkkltsshlk 347
Cdd:COG0642 78 LLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDEEQR------------- 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 348 rfidegiENLDLIYRNLNRAADLISNFKKVAVIQDDGVNTY---INVHKLISDVLTSIQSELLPKKPVVTINCPTDLA-I 423
Cdd:COG0642 145 -------EYLETILRSADRLLRLINDLLDLSRLEAGKLELEpepVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPtV 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 424 HSKSEPLQQVFQQLLMNSVIHGfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSK--RGQGASGLG 501
Cdd:COG0642 218 RGDPDRLRQVLLNLLSNAIKYT---PEGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDpsRRGGGTGLG 294
|
250 260 270
....*....|....*....|....*....|...
gi 743333863 502 MHLVYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:COG0642 295 LAIVKRIV-ELHGGTIEVESEPGKGTTFTVTLP 326
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
269-534 |
5.30e-29 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 114.62 E-value: 5.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 269 ALREANQELlstlERMHQYQTQivenekmaslgqMVAGVAHEVNTPIGLGITGSTLLRDKLADIQqsfddkkltsshlkr 348
Cdd:COG2205 1 ELEEALEEL----EELERLKSE------------FLANVSHELRTPLTSILGAAELLLDEEDLSP--------------- 49
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 349 fiDEGIENLDLIYRNLNRAADLISNFKKVAVIQDDGVN---TYINVHKLISDVLTSIQSELLPKKPVVTINCPTDLA-IH 424
Cdd:COG2205 50 --EERRELLEIIRESAERLLRLIEDLLDLSRLESGKLSlelEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPlVY 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 425 SKSEPLQQVFQQLLMNSVIHGfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSK--RGQGASGLGM 502
Cdd:COG2205 128 ADPELLEQVLANLLDNAIKYS---PPGGTITISARREGDGVRISVSDNGPGIPEEELERIFERFYRGDnsRGEGGTGLGL 204
|
250 260 270
....*....|....*....|....*....|..
gi 743333863 503 HLVYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:COG2205 205 AIVKRIV-EAHGGTIWVESEPGGGTTFTVTLP 235
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
145-534 |
5.86e-22 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 97.70 E-value: 5.86e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 145 QVVGYVYMRGSLESLEVYIERKILIDVLLTLLILAVVYFIAIKVQRRIAKPIEQLSVLLQDVSKNHNYDARAPVTDVKEI 224
Cdd:COG5002 12 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 225 SALSNSLNIMLTRTKKQLERHEKDKQEIKQLNLSLEEKVNQRTIALREANQELLSTLERMHQYQTQIVENEKMASlgQMV 304
Cdd:COG5002 92 LLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRR--EFV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 305 AGVAHEVNTPIGlGITGST-LLRDKLADiqqsfDDKKLtsshlKRFidegienLDLIYRNLNRAADLISNFKKVAVIQDD 383
Cdd:COG5002 170 ANVSHELRTPLT-SIRGYLeLLLDGAAD-----DPEER-----REY-------LEIILEEAERLSRLVNDLLDLSRLESG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 384 GVN---TYINVHKLISDVLTSIQSELLPKKPVVTINCPTDLA-IHSKSEPLQQVFQQLLMNSVIHGfigKENNEIRFDVE 459
Cdd:COG5002 232 ELKlekEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLlVLGDPDRLEQVLTNLLDNAIKYT---PEGGTITVSLR 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 743333863 460 LVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSK----RGQGASGLGMHLVYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:COG5002 309 EEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDksrsRETGGTGLGLAIVKHIV-EAHGGRIWVESEPGKGTTFTITLP 386
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
116-534 |
2.82e-20 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 94.08 E-value: 2.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 116 LRIDSVEELKTPRITNDHIELTRPIYDNEQVVGYVYMRGSLESLEVYIERKILIDVLLTLLILAVVYFIAIKVQRRIAKP 195
Cdd:COG4251 127 LLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 196 IEQLSVLLQDVSKNHNYDARAPVTDVKEISALSNSLNIMLTRTKKQLERHEKDkqeikqLNLSLEEKVNQRTIALREANQ 275
Cdd:COG4251 207 LELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRL------ELEELEEELEERTAELERSNE 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 276 ELlstlermhqyqtqivenekmaslGQMVAGVAHEVNTPIgLGITG-STLLRDKLADiqqsfddkkltsshlkRFIDEGI 354
Cdd:COG4251 281 EL-----------------------EQFAYVASHDLREPL-RKISGfSQLLEEDYGD----------------KLDEEGR 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 355 ENLDLIYRNLNRAADLIS---NFKKVAviQDDGVNTYINVHKLISDVLTSIQSELLPKKpvVTINCPTDLAIHSKSEPLQ 431
Cdd:COG4251 321 EYLERIRDAAERMQALIDdllAYSRVG--RQELEFEPVDLNELLEEVLEDLEPRIEERG--AEIEVGPLPTVRGDPTLLR 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 432 QVFQQLLMNSVIHGfIGKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVT--SKRGQGASGLGMHLVYNLV 509
Cdd:COG4251 397 QVFQNLISNAIKYS-RPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRlhSRDEYEGTGIGLAIVKKIV 475
|
410 420
....*....|....*....|....*
gi 743333863 510 tQALGGRVMFDLEEKRGARFIITIP 534
Cdd:COG4251 476 -ERHGGRIWVESEPGEGATFYFTLP 499
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
428-534 |
1.86e-19 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 83.85 E-value: 1.86e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 428 EPLQQVFQQLLMNSVIHGfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSK---RGQGASGLGMHL 504
Cdd:smart00387 4 DRLRQVLSNLLDNAIKYT---PEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDkrsRKIGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|
gi 743333863 505 VYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:smart00387 81 VKKLV-ELHGGEISVESEPGGGTTFTITLP 109
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
282-534 |
1.07e-17 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 85.57 E-value: 1.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 282 ERMHQYQTQIVENEKMASLGQMVAGVAHEVNTPIGLGITGSTLLRDKLADIQQSFddkkltsshlkrfidegieNLDLIY 361
Cdd:COG5808 223 KTLLERVIQEINTQKLELIGTFAASTAHEIRNPLTSIKGFIQLLQEKYPELEDQK-------------------YFDIIQ 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 362 RNLNRAADLISNFKKVAVIQDDGVNTYiNVHKLISDVLTSIQSELLPKKPVVTINCPTD-LAIHSKSEPLQQVFQQLLMN 440
Cdd:COG5808 284 EEIQRINQIVSEFLVLGKPTAKKLELD-DLNELIEEILSIIDSEANLKNIRVEKQSLDEpLHIKCDKDRIKQVLLNLIKN 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 441 SVIHGfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrgQGASGLGMHLVYNLVtQALGGRVMFD 520
Cdd:COG5808 363 AIEAM---KEGGKLTISIENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTK--EGGTGLGLSVCKRIV-EMHGGEIDIE 436
|
250
....*....|....
gi 743333863 521 LEEKRGARFIITIP 534
Cdd:COG5808 437 SEEGKGTTFTIRLP 450
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
426-534 |
4.51e-15 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 71.25 E-value: 4.51e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 426 KSEPLQQVFQQLLMNSVIHGfigKENNEIRFDVElVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTS-KRGQGASGLGMHL 504
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHA---AKAGEITVTLS-EGGELTLTVEDNGIGIPPEDLPRIFEPFSTAdKRGGGGTGLGLSI 77
|
90 100 110
....*....|....*....|....*....|
gi 743333863 505 VYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:pfam02518 78 VRKLV-ELLGGTITVESEPGGGTTVTLTLP 106
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
165-527 |
9.82e-15 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 77.03 E-value: 9.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 165 RKILIDVLLT--LLILAVVYFIaikVQRRIAKPIEQLSVLLQDVSKNHnYDARAPVTDVKEISALSNSLnimltrtkkql 242
Cdd:COG4192 325 GILLLAIALLslLLAVLINYFY---VRRRLVKRLNALSDAMAAIAAGD-LDVPIPVDGNDEIGRIARLL----------- 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 243 eRHEKDKqeIKQLNLSLEEKVNQRTIA---LREANQELLSTlermhqyqtqivenEKMASLGQMVAGVAHEVNTPigLGI 319
Cdd:COG4192 390 -RVFRDQ--AIEKTQELETEIEERKRIeknLRQTQDELIQA--------------AKMAVVGQTMTSLAHELNQP--LNA 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 320 TGSTLLRDKLADIQQSFDdkKLTSSHLKrfIDEGIENLDLIYRNLNraadlisNFKKvaviQDDGVNTYINVHKLISDVL 399
Cdd:COG4192 451 MSMYLFSAKKALEQENYA--QLPTSLDK--IEGLIERMDKIIKSLR-------QFSR----KSDTPLQPVDLRQVIEQAW 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 400 TSIQSELLPKKpvVTINCPTDLAIHSKSEPLQQVFQQLLMNSVIhgfIGKENNEIRFDVELVGKKLTIVYSDNGQGVdkN 479
Cdd:COG4192 516 ELVESRAKPQQ--ITLHIPDDLMVQGDQVLLEQVLVNLLVNALD---AVATQPQISVDLLSNAENLRVAISDNGNGW--P 588
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 743333863 480 IKNRIFDPFVTSKrgQGASGLGMHLVYNLVTQaLGGRVMFDLEEKRGA 527
Cdd:COG4192 589 LVDKLFTPFTTTK--EVGLGLGLSICRSIMQQ-FGGDLYLASTLERGA 633
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
270-534 |
1.61e-14 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 76.16 E-value: 1.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 270 LREANQELLSTL-------ERMhQYQTQIVENEKMASLGQMVAGVAHEVNTPIglgitgsTLLRDKLADIQQSFDDKklt 342
Cdd:PRK11360 354 LHNTHGEMIGALvifsdltERK-RLQRRVARQERLAALGELVAGVAHEIRNPL-------TAIRGYVQIWRQQTSDP--- 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 343 sshlkrfidEGIENLDLIYR---NLNRAADLISNFKKVAVIQddgvNTYINVHKLISDVLTSIQSELLPKKPVVTINCPT 419
Cdd:PRK11360 423 ---------PSQEYLSVVLRevdRLNKVIDQLLEFSRPRESQ----WQPVSLNALVEEVLQLFQTAGVQARVDFETELDN 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 420 DL-AIHSKSEPLQQVFQQLLMNSV--IhgfigKENNEIRFDVELVG-KKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrgQ 495
Cdd:PRK11360 490 ELpPIWADPELLKQVLLNILINAVqaI-----SARGKIRIRTWQYSdGQVAVSIEDNGCGIDPELLKKIFDPFFTTK--A 562
|
250 260 270
....*....|....*....|....*....|....*....
gi 743333863 496 GASGLGMHLVYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:PRK11360 563 KGTGLGLALSQRII-NAHGGDIEVESEPGVGTTFTLYLP 600
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
5.14e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 68.22 E-value: 5.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSV--IHGFigkenNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRGQGASGLGMHLVYN 507
Cdd:cd16943 4 LNQVLLNLLVNAAqaMEGR-----GRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTGLGLSLSYR 78
|
90 100
....*....|....*....|....*..
gi 743333863 508 LVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16943 79 II-QKHGGTIRVASVPGGGTRFTIILP 104
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
281-534 |
1.63e-13 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 72.51 E-value: 1.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 281 LERMHQYQTQIVENEKMASLGQMVAGVAHEVNTPIGlGITG-STLLRDK---------LADIQQSFDDKkltsshLKRFI 350
Cdd:PRK10364 218 LRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLS-SIKGlAKYFAERapaggeahqLAQVMAKEADR------LNRVV 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 351 DEGIEnldliyrnLNRAADLisnfkkvaVIQDDGVNTYIN-VHKLISDVLTS--IQSELLPKKPVVTINCPTDlaihsks 427
Cdd:PRK10364 291 SELLE--------LVKPTHL--------ALQAVDLNDLINhSLQLVSQDANSreIQLRFTANDTLPEIQADPD------- 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 428 ePLQQVFQQLLMNSvIHGfIGkENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrGQGaSGLGMHLVYN 507
Cdd:PRK10364 348 -RLTQVLLNLYLNA-IQA-IG-QHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK-AEG-TGLGLAVVHN 421
|
250 260
....*....|....*....|....*..
gi 743333863 508 LVTQAlGGRVMFDLEEKRGARFIITIP 534
Cdd:PRK10364 422 IVEQH-GGTIQVASQEGKGATFTLWLP 447
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
294-534 |
4.17e-13 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 71.69 E-value: 4.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 294 NEKMASLGQMVAGVAHEVNTPIglgitgsTLLRDKLADIQQSFDDKKltsshlkrfidegiENLDLIYRNLNRAADLISN 373
Cdd:COG5805 281 SEKLSIAGQLAAGIAHEIRNPL-------TSIKGFLQLLQPGIEDKE--------------EYFDIMLSELDRIESIISE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 374 FKKVAviQDDGVN-TYINVHKLISDVLTSIQSE-LLPKKPVVTINCPTDLAIHSKSEPLQQVFQQLLMNSV--------I 443
Cdd:COG5805 340 FLALA--KPQAVNkEKENINELIQDVVTLLETEaILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIeampnggtI 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 444 HGFIGKENNEIRFDVElvgkkltivysDNGQGVDKNIKNRIFDPFVTSKrgQGASGLGMHLVYNLVTQAlGGRVMFDLEE 523
Cdd:COG5805 418 TIHTEEEDNSVIIRVI-----------DEGIGIPEERLKKLGEPFFTTK--EKGTGLGLMVSYKIIENH-NGTIDIDSKV 483
|
250
....*....|.
gi 743333863 524 KRGARFIITIP 534
Cdd:COG5805 484 GKGTTFTITLP 494
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
282-534 |
7.28e-13 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 70.77 E-value: 7.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 282 ERMhQYQTQIVENEKMASLGQMVAGVAHEVNTPiglgitgstllrdkladiqqsfddkkLTSshLKRFI--------DEG 353
Cdd:COG5809 253 ERK-KLEELLRKSEKLSVVGELAAGIAHEIRNP--------------------------LTS--LKGFIqllkdtidEEQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 354 IENLDLIYRNLNRAADLISNFKKVAVIQDDGVNTyINVHKLISDVLTSIQSELLPKKPVVTINCPTDLA-IHSKSEPLQQ 432
Cdd:COG5809 304 KTYLDIMLSELDRIESIISEFLVLAKPQAIKYEP-KDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPdILGDENQLKQ 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 433 VFQQLLMNSvIHGFigKENNEIRFDV-ELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSK-RGqgaSGLGMHLVYNLVT 510
Cdd:COG5809 383 VFINLLKNA-IEAM--PEGGNITIETkAEDDDKVVISVTDEGCGIPEERLKKLGEPFYTTKeKG---TGLGLMVSYKIIE 456
|
250 260
....*....|....*....|....
gi 743333863 511 QaLGGRVMFDLEEKRGARFIITIP 534
Cdd:COG5809 457 E-HGGKITVESEVGKGTTFSITLP 479
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
281-534 |
1.67e-12 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 69.13 E-value: 1.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 281 LERMHQYQtQIVENEKMASLGQMVAGVAHEVNTPIglgitgsTLLRDKLADIQQsfddKKLTSSHLKRFIDEGIENLDli 360
Cdd:COG5806 183 IENILLRK-ELQRAEKLEVVSELAASIAHEVRNPL-------TVVRGFIQLLQE----PELSDEKRKQYIRIALEELD-- 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 361 yrnlnRAADLISNFKKVAVIQDDGVNTyINVHKLISDVLTSIQSELLPKKPVVTINCPTDLAIHSKSEPLQQVFQQLLMN 440
Cdd:COG5806 249 -----RAEAIITDYLTFAKPQPEKLEK-IDVSEELEHVIDVLSPYANMNNVEIQTELEPGLYIEGDRQKLQQCLINIIKN 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 441 SV--IhgfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrGQGaSGLGMHLVYNLVtQALGGRVM 518
Cdd:COG5806 323 GIeaM-----PNGGTLTIDVSIDKNKVIISIKDTGVGMTKEQLERLGEPYFSTK-EKG-TGLGTMVSYRII-EAMNGTIR 394
|
250
....*....|....*.
gi 743333863 519 FDLEEKRGARFIITIP 534
Cdd:COG5806 395 VESEVGKGTTFTITLP 410
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
447-534 |
2.02e-12 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 68.72 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 447 IGKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRGQGaSGLGMHLVYNLVTQaLGGRVMFDLEEKRG 526
Cdd:COG3290 300 LPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTKLGEG-RGLGLALVKQIVEK-YGGTIEVESEEGEG 377
|
....*...
gi 743333863 527 ARFIITIP 534
Cdd:COG3290 378 TVFTVRLP 385
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-529 |
3.85e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 62.47 E-value: 3.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSV--IHGFigkENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKR-GQGaSGLGMHLVY 506
Cdd:cd16976 1 IQQVLMNLLQNALdaMGKV---ENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPvGKG-TGLGLSISY 76
|
90 100
....*....|....*....|...
gi 743333863 507 NLVtQALGGRVMFDLEEKRGARF 529
Cdd:cd16976 77 GIV-EEHGGRLSVANEEGAGARF 98
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
389-534 |
6.60e-12 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 67.62 E-value: 6.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 389 INVHKLISDVLTSIQSELLPKKPVVTINCP-----TDLAIhsksePLQQVFQQLLMNSVIHGFIGKENNEIRFDVELVGK 463
Cdd:COG3920 359 VDLRDYLRELLEPLRDSYGGRGIRIELDGPdvelpADAAV-----PLGLILNELVTNALKHAFLSGEGGRIRVSWRREDG 433
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 743333863 464 KLTIVYSDNGQGVDKNiknriFDPfvtskrgQGASGLGMHLVYNLVTQaLGGRVmfDLEEKRGARFIITIP 534
Cdd:COG3920 434 RLRLTVSDNGVGLPED-----VDP-------PARKGLGLRLIRALVRQ-LGGTL--ELDRPEGTRVRITFP 489
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
172-534 |
7.38e-12 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 68.13 E-value: 7.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 172 LLTLLILAVVYFIAIkvQRRIAKPIEQLsVLLQDVSKNHNYDARAPVTDVKEISALSNSLNIMLTRTKKQLErhekdkqe 251
Cdd:PRK15347 303 LLILVLLTSVLFLLL--RRYLAKPLWRF-VDIINKTGPAALEPRLPENRLDELGSIAKAYNQLLDTLNEQYD-------- 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 252 ikqlnlSLEEKVNQRTIALREANQELlstlERMHQYQTqivenEKMASlgqmvagVAHEVNTPIGlGITGS-TLLRDKLA 330
Cdd:PRK15347 372 ------TLENKVAERTQALAEAKQRA----EQANKRKS-----EHLTT-------ISHEIRTPLN-GVLGAlELLQNTPL 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 331 DIQQsfddKKL--TSSHLKRFIDEGIENLdLIYRNLnRAADLISNFKKVAVIQddgvntyinvhkLISDVLTSIQSELLP 408
Cdd:PRK15347 429 TAEQ----MDLadTARQCTLSLLAIINNL-LDFSRI-ESGQMTLSLEETALLP------------LLDQAMLTIQGPAQS 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 409 KK----PVVTINCPTDLAIHSKSepLQQVFQQLLMNSVihGFigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRI 484
Cdd:PRK15347 491 KSltlrTFVGAHVPLYLHLDSLR--LRQILVNLLGNAV--KF--TETGGIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQI 564
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 743333863 485 FDPFVTSKRGQGASGLGMHLVYNLvTQALGGRVMFDLEEKRGARFIITIP 534
Cdd:PRK15347 565 FTPFYQADTHSQGTGLGLTIASSL-AKMMGGELTLFSTPGVGSCFSLVLP 613
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
462-534 |
1.01e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 62.01 E-value: 1.01e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 743333863 462 GKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKR-GQGaSGLGMHLVYNLVTQaLGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16919 45 GNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEvGKG-TGLGLSMVYGFVKQ-SGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
433-534 |
4.72e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 59.61 E-value: 4.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 433 VFQQLLMNSVIHGfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRG---QGASGLGMHLVyNLV 509
Cdd:cd16948 9 IIGQIVSNALKYS---KQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGrnfQESTGMGLYLV-KKL 84
|
90 100
....*....|....*....|....*
gi 743333863 510 TQALGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16948 85 CDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
3.15e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 57.41 E-value: 3.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSV---IHGfiGKENNEIRFDVELVGKK-LTIVYSDNGQGVDKNIKNRIFDPFVTSKrgqgASGLGMHLV 505
Cdd:cd16920 1 IQQVLINLVRNGIeamSEG--GCERRELTIRTSPADDRaVTISVKDTGPGIAEEVAGQLFDPFYTTK----SEGLGMGLS 74
|
90 100 110
....*....|....*....|....*....|
gi 743333863 506 YNL-VTQALGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16920 75 ICRsIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
295-534 |
4.27e-10 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 62.39 E-value: 4.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 295 EKMASLGQMVAGVAHEVNTpiglgITGSTLLRDKLADiqqsfdDKKLTSSHLKRFIDEgienldlIYRNLNRAADLISNF 374
Cdd:PRK13837 445 RRLEAVGTLASGIAHNFNN-----ILGAILGYAEMAL------NKLARHSRAARYIDE-------IISAGARARLIIDQI 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 375 KKVAVIQDdgvntYINVHKLISDVLTSIQSEL---LPkkPVVTINCPTDLAIHSKS-EPLQqvFQQLLMN---SVIHGFI 447
Cdd:PRK13837 507 LAFGRKGE-----RNTKPFDLSELVTEIAPLLrvsLP--PGVELDFDQDQEPAVVEgNPAE--LQQVLMNlcsNAAQAMD 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 448 GKENNEIRFDVELVGKKLTIVY-------------SDNGQGVDKNIKNRIFDPFVTSkRGQGaSGLGMHLVYNLVtQALG 514
Cdd:PRK13837 578 GAGRVDISLSRAKLRAPKVLSHgvlppgryvllrvSDTGAGIDEAVLPHIFEPFFTT-RAGG-TGLGLATVHGIV-SAHA 654
|
250 260
....*....|....*....|
gi 743333863 515 GRVMFDLEEKRGARFIITIP 534
Cdd:PRK13837 655 GYIDVQSTVGRGTRFDVYLP 674
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
159-277 |
5.08e-09 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 58.71 E-value: 5.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 159 LEVYIERK----ILIDVLLTLLILAVVYFIAIKVQRRIAKPIEQLSVLLQDVSKNHNYDARAPVTDVKEISALSNSLNIM 234
Cdd:PRK10935 139 LQHFAERKlillAAISLLGLILILTLVFFTVRFTRRQVVAPLNQLVTASQQIEKGQFDHIPLDTTLPNELGLLAKAFNQM 218
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 743333863 235 LTrtkkqlerhekdkqEIKQLNLSLEEKVNQRTIALREANQEL 277
Cdd:PRK10935 219 SS--------------ELHKLYRSLEASVEEKTRKLTQANRSL 247
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
1.66e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 52.43 E-value: 1.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVIHGfigkeNNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFV----TSKRGQGASGLGMHLV 505
Cdd:cd16939 1 MARALDNLLRNALRYA-----HRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVrldpSRDRATGGFGLGLAIV 75
|
90 100
....*....|....*....|....*....
gi 743333863 506 YNlVTQALGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16939 76 HR-VALWHGGHVECDDSELGGACFRLTWP 103
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
2.63e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 52.08 E-value: 2.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVIHGFIGkenNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFV---TSK-RGQGASGLGMHLV 505
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTG---GKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYrveSSRnRASGGSGLGLAIC 81
|
90 100
....*....|....*....|....*....
gi 743333863 506 YNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16946 82 HNIA-LAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
3.28e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 51.56 E-value: 3.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVihGFIGK-ENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPF--VTSKRGQGASGLGMHLVY 506
Cdd:cd16921 1 LGQVLTNLLGNAI--KFRRPrRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFqrLHSREEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*...
gi 743333863 507 NLVTQAlGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16921 79 KIIERH-GGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
3.57e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 51.63 E-value: 3.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVihGFIGKENNEIR------FDVELVGKK----LTIVYSDNGQGVDKNIKNRIFDPFVTSKrgQGASG 499
Cdd:cd16918 1 LIQVFLNLVRNAA--QALAGSGGEIIlrtrtqRQVTLGHPRhrlaLRVSVIDNGPGIPPDLQDTIFYPMVSGR--ENGTG 76
|
90 100 110
....*....|....*....|....*....|....*
gi 743333863 500 LGMHLVYNLVTQAlGGRVMFDLEEKRgARFIITIP 534
Cdd:cd16918 77 LGLAIAQNIVSQH-GGVIECDSQPGH-TVFSVSLP 109
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
149-533 |
4.27e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 55.41 E-value: 4.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 149 YVYMRGSLESLEVYIERKILIDVLLTLLILAVVYFIAIKVQRRIAKPIEQLSVLLQDVSKNHNydARAPVTDVKEISALS 228
Cdd:COG2972 138 TLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDL--VRLEVSGNDEIGILA 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 229 NSLNIMLTRTKKQLERHEKDKQEIKQLNLsleekvnqrtialrEANQE------LLSTLERMHQYqtqiVENEKMASLGQ 302
Cdd:COG2972 216 RSFNEMVERIKELIEEVYELELEKKEAEL--------------KALQAqinphfLFNTLNSIRWL----AELEDPEEAEE 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 303 MVAGVAHevntpiglgitgstLLRDkladiqqsfddkkltsshlkrfidegienldliyrNLNRAADLISNFKKVAVIQD 382
Cdd:COG2972 278 MLEALSK--------------LLRY-----------------------------------SLSKGDELVTLEEELELIKS 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 383 dgvntYInvhklisdvltSIQSELLPKKPVVTINCPTDLaIHSKSEPLqqVFQQLLMNSVIHGFIGK-ENNEIRFDVELV 461
Cdd:COG2972 309 -----YL-----------EIQKLRFGDRLEVEIEIDEEL-LDLLIPKL--ILQPLVENAIEHGIEPKeGGGTIRISIRKE 369
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 743333863 462 GKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRGqgaSGLGMHLVYNLVTQALGGRVMFDLEEKRGARFIITI 533
Cdd:COG2972 370 GDRLVITVEDNGVGMPEEKLEKLLEELSSKGEG---RGIGLRNVRERLKLYYGEEYGLEIESEPGEGTTVTI 438
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
169-374 |
3.24e-07 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 52.96 E-value: 3.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 169 IDVLLTLLILAVVYFIAIKVQRRIAKPIEQLSVLLQDVSkNHNYDARAPVTDVKEISALSNSLNIMLTRTKKQLERHEKD 248
Cdd:COG3850 119 LALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIA-RGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEEE 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 249 KQEIKQLNLSLEEKVNQRTIALREANQELLSTLERMHQYQTQIVENEKMASLGQMVAGVAHEVNTPIGLGITGSTLLRDK 328
Cdd:COG3850 198 EELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASA 277
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 743333863 329 LADIQQSFDDKKLTSSHLKRFIDEGIENLDLIYRNLNRAADLISNF 374
Cdd:COG3850 278 LLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAI 323
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
430-534 |
5.54e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 48.26 E-value: 5.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSV---IHGFI---------GKENNEIRFDVElvgkkltivysDNGQGVDKNIKNRIFDPFV----TSKR 493
Cdd:cd16922 1 LRQILLNLLGNAIkftEEGEVtlrvsleeeEEDGVQLRFSVE-----------DTGIGIPEEQQARLFEPFSqadsSTTR 69
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 743333863 494 GQGASGLGMHLVYNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16922 70 KYGGTGLGLAISKKLV-ELMGGDISVESEPGQGSTFTFTLP 109
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
448-534 |
1.06e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 47.28 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 448 GKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrGQGASGLGMHLVYNLVTQaLGGRVMFDLEEKRGA 527
Cdd:cd16915 20 GAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTK-GQGERGIGLALVRQSVER-LGGSITVESEPGGGT 97
|
....*..
gi 743333863 528 RFIITIP 534
Cdd:cd16915 98 TFSIRIP 104
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
437-509 |
1.12e-06 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 47.60 E-value: 1.12e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 743333863 437 LLMNSVIHGFIGKENNEIRFDVELVGKKLTIVYSDNGQGVDkniKNRIFDPFVTSKRGqgasGLGMHLVYNLV 509
Cdd:COG2172 42 AVTNAVRHAYGGDPDGPVEVELELDPDGLEIEVRDEGPGFD---PEDLPDPYSTLAEG----GRGLFLIRRLM 107
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
282-526 |
1.74e-06 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 50.44 E-value: 1.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 282 ERMHQYQtqiveneKMASLGQMVAGVAHEVNTPIGLgITGSTLLrdkladIQQSFDDKKLTSSHLKRFIDEgienldlIY 361
Cdd:PRK13557 152 DALRQAQ-------KMEALGQLTGGIAHDFNNLLQV-MSGYLDV------IQAALSHPDADRGRMARSVEN-------IR 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 362 RNLNRAADLISNFKKVAVIQD-DGvnTYINVHKLISDVL----------TSIQSELLPKKPvvtiNCPTDlaihsksePL 430
Cdd:PRK13557 211 AAAERAATLTQQLLAFARKQRlEG--RVLNLNGLVSGMGelaertlgdaVTIETDLAPDLW----NCRID--------PT 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 431 QQ--VFQQLLMNS---VIHG---FIGKENNEIR------FDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSK-RGQ 495
Cdd:PRK13557 277 QAevALLNVLINArdaMPEGgrvTIRTRNVEIEdedlamYHGLPPGRYVSIAVTDTGSGMPPEILARVMDPFFTTKeEGK 356
|
250 260 270
....*....|....*....|....*....|.
gi 743333863 496 GaSGLGMHLVYNLVTQAlGGRVMFDLEEKRG 526
Cdd:PRK13557 357 G-TGLGLSMVYGFAKQS-GGAVRIYSEVGEG 385
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
9-338 |
3.28e-06 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 49.73 E-value: 3.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 9 SIRKALINLIMLITAICLSLSISISTYLSVKEQKQLIVNKLVILSEIVAFDAGQSVIEDDRKTEEKRLKSFEKIPLVKNI 88
Cdd:COG2770 53 LLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 89 HIYSIEKASQKPVFFISFNAKKTPPVPLRIDSVEELKTPRITNDHIELTRPIYDNEQVVGYVYMRGSLESLEVYIERKIL 168
Cdd:COG2770 133 ALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALL 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 169 IDVLLTLLILAVVYFIAIKVQRRIAKPIEQLSVLLQDVSKNhNYDARAPVTDVKEISALSNSLNIMLTRTKKQLERHEKD 248
Cdd:COG2770 213 LLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAG-DLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEE 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 249 KQEIKQLNLSLEEKVNQRTIALREANQELLSTLERMHQYQTQIVENEKMASLGQMVAGVAHEVNTPIGLGITGSTLLRDK 328
Cdd:COG2770 292 EELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEA 371
|
330
....*....|
gi 743333863 329 LADIQQSFDD 338
Cdd:COG2770 372 ELLVLLALEA 381
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
370-534 |
3.59e-06 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 50.03 E-value: 3.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 370 LISNFKKVAVIQDDGVN---TYINVHKLISDVLTSIQSeLLPKKPVvTINCPTDLA-IHSKSEPLQQVFQQLLMNSviHG 445
Cdd:PRK10490 717 LVNNLLDMARIQSGGFNlrkEWLTLEEVVGSALQMLEP-GLSGHPI-NLSLPEPLTlIHVDGPLFERVLINLLENA--VK 792
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 446 FIGkENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFvtsKRGQGAS---GLGMHLVynlVTQAL----GGRVM 518
Cdd:PRK10490 793 YAG-AQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKF---ARGNKESaipGVGLGLA---ICRAIvevhGGTIW 865
|
170
....*....|....*.
gi 743333863 519 FDLEEKRGARFIITIP 534
Cdd:PRK10490 866 AENRPEGGACFRVTLP 881
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
274-534 |
7.61e-06 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 48.48 E-value: 7.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 274 NQeLLSTLERmhqyqtqiveNEKMASlgQMVAGVAHEVNTPIglgitgsTLLRDKLADIQQSFddKKLTSSHLKRFIDEg 353
Cdd:PRK10549 227 NQ-LASTLEK----------NEQMRR--DFMADISHELRTPL-------AVLRGELEAIQDGV--RKFTPESVASLQAE- 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 354 IENLDLIYRNLNRAAdlisnfkkvavIQDDGVNTY----INVHKLISDVLTSIQSELLPKKPVVTINCPTDLAIHSKSEP 429
Cdd:PRK10549 284 VGTLTKLVDDLHQLS-----------LSDEGALAYrktpVDLVPLLEVAGGAFRERFASRGLTLQLSLPDSATVFGDPDR 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVIHGfigKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSK----RGQGASGLGMHLV 505
Cdd:PRK10549 353 LMQLFNNLLENSLRYT---DSGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEgsrnRASGGSGLGLAIC 429
|
250 260
....*....|....*....|....*....
gi 743333863 506 YNLVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:PRK10549 430 LNIV-EAHNGRIIAAHSPFGGVSITVELP 457
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
279-534 |
8.35e-06 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 48.45 E-value: 8.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 279 STLER----MHQYQTQIveNEKMASLGQMVAGVAHEVNTPIglgitgsTLLRDKLADIQQSFDDKKLTsshLKRFI---D 351
Cdd:PRK10604 189 SSLERlgvaFNQMADNI--NALIASKKQLIDGIAHELRTPL-------VRLRYRLEMSDNLSAAESQA---LNRDIgqlE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 352 EGIENLdLIYRNLNRAadlisnfkkvaviQDDGVNTYINVHKLISDVLTSIQSeLLPKKPVVTINCPTDLAIHSKSEPLQ 431
Cdd:PRK10604 257 ALIEEL-LTYARLDRP-------------QNELHLSEPDLPAWLSTHLADIQA-VTPEKTVRLDTPHQGDYGALDMRLME 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 432 QVFQQLLMNSVIHGfigkeNNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFV----TSKRGQGASGLGMHLVYN 507
Cdd:PRK10604 322 RVLDNLLNNALRYA-----HSRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVrldpSRDRATGGCGLGLAIVHS 396
|
250 260
....*....|....*....|....*..
gi 743333863 508 LVtQALGGRVMFDLEEKRGARFIITIP 534
Cdd:PRK10604 397 IA-LAMGGSVNCDESELGGARFSFSWP 422
|
|
| HATPase_LytS-like |
cd16957 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
433-534 |
1.47e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis LytS and Staphylococcus aureus LytS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and a GAF sensor domain; most contain a DUF3816 domain.
Pssm-ID: 340433 [Multi-domain] Cd Length: 106 Bit Score: 43.95 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 433 VFQQLLMNSVIHGFIG-KENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRGQGASglgmhlVYNLVTQ 511
Cdd:cd16957 5 ALQVLVENAIRHAFPKrKENNEVRVVVKKDQHKVHVSVSDNGQGIPEERLDLLGKTTVTSEKGTGTA------LENLNRR 78
|
90 100
....*....|....*....|....*...
gi 743333863 512 ALG-----GRVMFDLEEKRGARFIITIP 534
Cdd:cd16957 79 LIGlfgseACLHIESEVHGGTEVWFVIP 106
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-517 |
1.87e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 43.59 E-value: 1.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVIHGfigkeNNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFV--TSKRGQGASGLGMHLVYN 507
Cdd:cd16950 1 LKRVLSNLVDNALRYG-----GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYrgDNARGTSGTGLGLAIVQR 75
|
90
....*....|
gi 743333863 508 LVTQaLGGRV 517
Cdd:cd16950 76 ISDA-HGGSL 84
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
397-534 |
2.20e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 44.33 E-value: 2.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 397 DVLTSIQSELLPKKPVvTINCPTDLAIHS--KSEPLQQVFQQLLMNSVIHGFIGKENNEIRFDVELVGKKLTIVYSDNGQ 474
Cdd:cd16951 6 NRIASAINAIHAVGDI-RINITGDTGPVSseVATAIGLVVNELLQNALKHAFSDREGGTITIRSVVDGDYLRITVIDDGV 84
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 475 GVDKNiknriFDPFVTSKrgqgasgLGMHLVYNLVTQALGGRVMFDLEEkRGARFIITIP 534
Cdd:cd16951 85 GLPQD-----EDWPNKGS-------LGLQIVRSLVEGELKAFLEVQSAE-NGTRVNIDIP 131
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
453-534 |
2.75e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 43.29 E-value: 2.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 453 EIRFDVEL-VGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrgQGASGLGMHLVYNLVTQAlGGRVMFDLEEKRGARFII 531
Cdd:cd16944 29 EVRIRVEAdQDGRIVLIVCDNGKGFPREMRHRATEPYVTTR--PKGTGLGLAIVKKIMEEH-GGRISLSNREAGGACIRI 105
|
...
gi 743333863 532 TIP 534
Cdd:cd16944 106 ILP 108
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
190-243 |
5.07e-05 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 41.08 E-value: 5.07e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 743333863 190 RRIAKPIEQLSVLLQDVSkNHNYDARAPVTDVKEISALSNSLNIMLTRTKKQLE 243
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIA-DGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
7.39e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 42.17 E-value: 7.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVihGFIGKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRGQGA----SGLGMHLV 505
Cdd:cd16953 1 LGQVLRNLIGNAI--SFSPPDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAfgqhSGLGLSIS 78
|
90 100 110
....*....|....*....|....*....|...
gi 743333863 506 YNLVtQALGGRVMFDLEEK----RGARFIITIP 534
Cdd:cd16953 79 RQII-EAHGGISVAENHNQpgqvIGARFTVQLP 110
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-534 |
1.24e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 41.16 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 430 LQQVFQQLLMNSVIHGfigkeNNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPF--VTSKRGQ--GASGLGMHLV 505
Cdd:cd16949 1 LARALENVLRNALRYS-----PSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFyrVDSARDResGGTGLGLAIA 75
|
90 100
....*....|....*....|....*....
gi 743333863 506 YNLVTQAlGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16949 76 ERAIEQH-GGKIKASNRKPGGLRVRIWLP 103
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
293-534 |
1.31e-04 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 44.17 E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 293 ENEKMA----SLGQMVAGVAHEVNTPIglgiTGSTLLRDKLADIQQSFDDKKlTSSHLKRFID------EGIENL--DLI 360
Cdd:PRK09303 140 ENETLLeqlkFKDRVLAMLAHDLRTPL----TAASLALETLELGQIDEDTEL-KPALIEQLQDqarrqlEEIERLitDLL 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 361 YRNLNRAADLISNFKKVaviqddgvntyiNVHKLISDVLTSIQSELLPKKPVVTINCPTDL-AIHSKSEPLQQVFQQLLM 439
Cdd:PRK09303 215 EVGRTRWEALRFNPQKL------------DLGSLCQEVILELEKRWLAKSLEIQTDIPSDLpSVYADQERIRQVLLNLLD 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 440 NSVIHGfigKENNEIRFDV-ELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKRGQGASGLGMHL-VYNLVTQALGGRV 517
Cdd:PRK09303 283 NAIKYT---PEGGTITLSMlHRTTQKVQVSICDTGPGIPEEEQERIFEDRVRLPRDEGTEGYGIGLsVCRRIVRVHYGQI 359
|
250
....*....|....*..
gi 743333863 518 MFDLEEKRGARFIITIP 534
Cdd:PRK09303 360 WVDSEPGQGSCFHFTLP 376
|
|
| HAMP |
pfam00672 |
HAMP domain; |
190-237 |
1.89e-04 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 39.14 E-value: 1.89e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 743333863 190 RRIAKPIEQLSVLLQDVSKNhNYDARAPVTDVKEISALSNSLNIMLTR 237
Cdd:pfam00672 4 RRILRPLRRLAEAARRIASG-DLDVRLPVSGRDEIGELARAFNQMAER 50
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
171-534 |
4.67e-04 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 42.97 E-value: 4.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 171 VLLTLLILAVVYFIAIKV-QRRIAKPIEQLSVLLQ---DVSKNHNYDARAPVTDVKEISALSNSLnimltRTK-KQLERH 245
Cdd:PRK11466 334 LLLGMVSLCALILILWRVvYRSVTRPLAEQTQALQrllDGDIDSPFPETAGVRELDTIGRLMDAF-----RSNvHALNRH 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 246 EKDkqeikqlnlsLEEKVNQRTIALREanqelLSTLERMHQYQTQIVENEKMASLGQMvagvAHEVNTPIgLGITGST-L 324
Cdd:PRK11466 409 REQ----------LAAQVKARTAELQE-----LVIEHRQARAEAEKASQAKSAFLAAM----SHEIRTPL-YGILGTAqL 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 325 LRDKLADIQQSFDDKKLTSSHlkrfidegiENLDLIyrnLNRAADLisnfkkvAVIQDDGVNTYIN-----VHKLISDVL 399
Cdd:PRK11466 469 LADNPALNAQRDDLRAITDSG---------ESLLTI---LNDILDY-------SAIEAGGKNVSVSdepfePRPLLESTL 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 400 TSIQSELLPKKPVVTINCPTDLAIHSKSEPLQqvFQQLLMNSVIHGFIGKENNEIRFDVELVGKKLTIVYSDNGQGVDKN 479
Cdd:PRK11466 530 QLMSGRVKGRPIRLATDIADDLPTALMGDPRR--IRQVITNLLSNALRFTDEGSIVLRSRTDGEQWLVEVEDSGCGIDPA 607
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 743333863 480 IKNRIFDPFVTSKRGQGASGLGMHLVYNLvTQALGGRVMFDLEEKRGARFIITIP 534
Cdd:PRK11466 608 KLAEIFQPFVQVSGKRGGTGLGLTISSRL-AQAMGGELSATSTPEVGSCFCLRLP 661
|
|
| HATPase_YehU-like |
cd16956 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
435-534 |
6.26e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.
Pssm-ID: 340432 [Multi-domain] Cd Length: 101 Bit Score: 39.34 E-value: 6.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 435 QQLLMNSVIHGFIGK-ENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPfvtskrgqGASGLGMHLVYNLVTQAL 513
Cdd:cd16956 7 QPIVENAVKHGLSGLlDGGRVEITARLDGQHLLLEVEDNGGGMDPDTLARILIR--------SSNGLGLNLVDKRLRQAF 78
|
90 100
....*....|....*....|...
gi 743333863 514 GGRVMFDLE--EKRGARFIITIP 534
Cdd:cd16956 79 GNDYGLDIEcaPGEGTRITIRLP 101
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
140-335 |
9.52e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 41.93 E-value: 9.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 140 IYDNEQVVGYVYMRGSLESLEVYIERKILIDVLLTLLILAVVyfIAIKVQRRIAKPIEQLSVLLQDVSKNhNYDARAPVT 219
Cdd:COG0840 156 AAAAAAALAALLEAAALALAAAALALALLAAALLALVALAII--LALLLSRSITRPLRELLEVLERIAEG-DLTVRIDVD 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 220 DVKEISALSNSLNIMLTRTKKQLERHekdKQEIKQLNLSLEE------KVNQRTIALREANQELLSTLERMHQYQTQIVE 293
Cdd:COG0840 233 SKDEIGQLADAFNRMIENLRELVGQV---RESAEQVASASEElaasaeELAAGAEEQAASLEETAAAMEELSATVQEVAE 309
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 743333863 294 N-EKMASLGQMVAGVAHEVNTPIGLGITGSTLLRDKLADIQQS 335
Cdd:COG0840 310 NaQQAAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAET 352
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
297-374 |
1.21e-03 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 37.19 E-value: 1.21e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 743333863 297 MASLGQMVAGVAHEVNTPIGLGITGSTLLRDKLADiqqsfddkkltsshlkrfIDEGIENLDLIYRNLNRAADLISNF 374
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLD------------------DEEQREYLERIREEAERLLRLINDL 60
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
303-514 |
2.41e-03 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 40.06 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 303 MVAGVAHEVNTPIGlGITGSTLLrdkLAdiqqsfddKKLTSSHLKRFIDEGIENLDLIyRNLnraadlisnFKKVAVIQD 382
Cdd:PRK11073 133 LVRGLAHEIKNPLG-GLRGAAQL---LS--------KALPDPALTEYTKVIIEQADRL-RNL---------VDRLLGPQR 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 383 DGVNTYINVHKLISDVLTsiqsellpkkpVVTINCPTDLAIHSKSEP-----------LQQVFQQLLMNSVihGFIGKEN 451
Cdd:PRK11073 191 PGTHVTESIHKVAERVVQ-----------LVSLELPDNVRLIRDYDPslpelahdpdqIEQVLLNIVRNAL--QALGPEG 257
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 743333863 452 NEIR------FDVELVGKKLTIVYS----DNGQGVDKNIKNRIFDPFVTSKrgQGASGLGMHLVYNLVTQALG 514
Cdd:PRK11073 258 GTITlrtrtaFQLTLHGERYRLAARidieDNGPGIPPHLQDTLFYPMVSGR--EGGTGLGLSIARNLIDQHSG 328
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
433-534 |
2.85e-03 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 39.60 E-value: 2.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 433 VFQQLLMNSVIHGfigkENNEIRFDVELVGKKLTIVYSDNGQGvdkniknriFDPFVTSKRGQGASGLGMHLvynlvtQA 512
Cdd:COG4585 166 IVQEALTNALKHA----GATRVTVTLEVDDGELTLTVRDDGVG---------FDPEAAPGGGLGLRGMRERA------EA 226
|
90 100
....*....|....*....|..
gi 743333863 513 LGGRVMFDLEEKRGARFIITIP 534
Cdd:COG4585 227 LGGTLTIGSAPGGGTRVRATLP 248
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
438-534 |
3.09e-03 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 40.28 E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333863 438 LMNSVIHGFIGKENNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFVTSKrGQGaSGLGMHLVyNLVTQALGGRV 517
Cdd:PRK11086 441 LIENALEAVGGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTK-GSN-RGVGLYLV-KQSVENLGGSI 517
|
90
....*....|....*..
gi 743333863 518 MFDLEEKRGARFIITIP 534
Cdd:PRK11086 518 AVESEPGVGTQFFVQIP 534
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
451-511 |
6.39e-03 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 39.15 E-value: 6.39e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 743333863 451 NNEIRFDVELVGKKLTIVYSDNGQGVDKNIKNRIFDPFV----TSKRGQGASGLGMHLVYNLVTQ 511
Cdd:PRK09470 370 HTKIEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYrvdeARDRESGGTGLGLAIVENAIQQ 434
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
467-534 |
7.30e-03 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 36.32 E-value: 7.30e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 743333863 467 IVYSDNGQGVDKNIKNRIFDPFV----TSKRGQGASGLGMHLVYNLVTQAlGGRVMFDLEEKRGARFIITIP 534
Cdd:cd16925 40 LTVSDSGPGIPPNLREEIFERFRqgdgSSTRAHGGTGLGLSIVKEFVELH-GGTVTVSDAPGGGALFQVELP 110
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
194-237 |
9.26e-03 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 34.34 E-value: 9.26e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 743333863 194 KPIEQLSVLLQDVSKNhNYDARAPVTDVKEISALSNSLNIMLTR 237
Cdd:cd06225 2 RPLRRLTEAARRIAEG-DLDVRVPVRSKDEIGELARAFNQMAER 44
|
|
| |
