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Conserved domains on  [gi|743333906|gb|KID40243|]
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regulator [Pseudoalteromonas distincta]

Protein Classification

DnaA regulatory inactivator Hda( domain architecture ID 11496820)

DnaA regulatory inactivator Hda mediates the interactions of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 1-227 1.93e-87

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 257.89  E-value: 1.93e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906    1 MALPVTLPDDETFASYFGGEDSLEVNHLKDSFSKLAKTFqyTYLCGLGDSGKSHLLYATCIKAQERGLSNMLLSMREVID 80
Cdd:TIGR03420   2 LPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRF--LYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   81 FGPMVLDGLEALDVLCIDDVHLVAGNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMLNISLPDLESRLTWGTTFQIRSM 160
Cdd:TIGR03420  80 ADPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPPL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 743333906  161 SDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKLDHASMAAQRKLTIPFIKSTLK 227
Cdd:TIGR03420 160 SDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
 
Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 1-227 1.93e-87

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 257.89  E-value: 1.93e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906    1 MALPVTLPDDETFASYFGGEDSLEVNHLKDSFSKLAKTFqyTYLCGLGDSGKSHLLYATCIKAQERGLSNMLLSMREVID 80
Cdd:TIGR03420   2 LPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRF--LYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   81 FGPMVLDGLEALDVLCIDDVHLVAGNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMLNISLPDLESRLTWGTTFQIRSM 160
Cdd:TIGR03420  80 ADPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPPL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 743333906  161 SDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKLDHASMAAQRKLTIPFIKSTLK 227
Cdd:TIGR03420 160 SDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
PRK08084 PRK08084
DnaA inactivator Hda;
1-228 1.92e-85

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 253.06  E-value: 1.92e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   1 MALPVTLPDDETFASYFGGEDSLEVNHLKDSFSKlaKTFQYTYLCGLGDSGKSHLLYATCIKAQERGLSNMLLSMREVID 80
Cdd:PRK08084   9 LSLPLYLPDDETFASFYPGDNDSLLAALQNALRQ--EHSGYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVPLDKRAW 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  81 FGPMVLDGLEALDVLCIDDVHLVAGNDAWEKALFNFFNRFNEPGKM-LVVTADLLPSMLNISLPDLESRLTWGTTFQIRS 159
Cdd:PRK08084  87 FVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRTrLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQP 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 743333906 160 MSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKLDHASMAAQRKLTIPFIKSTLKL 228
Cdd:PRK08084 167 LSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL 235
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
36-227 3.82e-44

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 149.96  E-value: 3.82e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  36 AKTFQYTYLCGLGDSGKSHLLYATCIKAQ-------------ERGLSNMLLSMRE--VIDFgpmvLDGLEALDVLCIDDV 100
Cdd:COG0593   31 GKAYNPLFLYGGVGLGKTHLLHAIGNEALennpgarvvyltaEEFTNDFINAIRNntIEEF----KEKYRSVDVLLIDDI 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906 101 HLVAGNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMLNISLPDLESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLEL 180
Cdd:COG0593  107 QFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLVVDIQPPDLETRIAILRKKAADRGLEL 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 743333906 181 SDECARFLLTRLSRDMRALLDVLDKLDHASMAAQRKLTIPFIKSTLK 227
Cdd:COG0593  187 PDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
Bac_DnaA pfam00308
Bacterial dnaA protein;
51-206 4.90e-16

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 73.90  E-value: 4.90e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   51 GKSHLLYATCIKAQE--RGLSNMLLSMREVI-DFGPMVLDG--------LEALDVLCIDDVHLVAGNDAWEKALFNFFNR 119
Cdd:pfam00308  46 GKTHLLHAIGNYALQnaPNLRVVYLTAEEFLnDFVDAIRDNktnqfkekYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNA 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  120 FNEPGKMLVVTADLLPSMLNiSLPD-LESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRA 198
Cdd:pfam00308 126 LHESGKQIVFSSDRPPKELE-ELEDrLRSRFQWGLVTDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRE 204


                  ....*...
gi 743333906  199 LLDVLDKL 206
Cdd:pfam00308 205 LEGALNRL 212
 
Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 1-227 1.93e-87

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 257.89  E-value: 1.93e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906    1 MALPVTLPDDETFASYFGGEDSLEVNHLKDSFSKLAKTFqyTYLCGLGDSGKSHLLYATCIKAQERGLSNMLLSMREVID 80
Cdd:TIGR03420   2 LPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRF--LYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   81 FGPMVLDGLEALDVLCIDDVHLVAGNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMLNISLPDLESRLTWGTTFQIRSM 160
Cdd:TIGR03420  80 ADPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPPL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 743333906  161 SDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKLDHASMAAQRKLTIPFIKSTLK 227
Cdd:TIGR03420 160 SDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
PRK08084 PRK08084
DnaA inactivator Hda;
1-228 1.92e-85

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 253.06  E-value: 1.92e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   1 MALPVTLPDDETFASYFGGEDSLEVNHLKDSFSKlaKTFQYTYLCGLGDSGKSHLLYATCIKAQERGLSNMLLSMREVID 80
Cdd:PRK08084   9 LSLPLYLPDDETFASFYPGDNDSLLAALQNALRQ--EHSGYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVPLDKRAW 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  81 FGPMVLDGLEALDVLCIDDVHLVAGNDAWEKALFNFFNRFNEPGKM-LVVTADLLPSMLNISLPDLESRLTWGTTFQIRS 159
Cdd:PRK08084  87 FVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRTrLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQP 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 743333906 160 MSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKLDHASMAAQRKLTIPFIKSTLKL 228
Cdd:PRK08084 167 LSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL 235
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
36-227 3.82e-44

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 149.96  E-value: 3.82e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  36 AKTFQYTYLCGLGDSGKSHLLYATCIKAQ-------------ERGLSNMLLSMRE--VIDFgpmvLDGLEALDVLCIDDV 100
Cdd:COG0593   31 GKAYNPLFLYGGVGLGKTHLLHAIGNEALennpgarvvyltaEEFTNDFINAIRNntIEEF----KEKYRSVDVLLIDDI 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906 101 HLVAGNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMLNISLPDLESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLEL 180
Cdd:COG0593  107 QFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLVVDIQPPDLETRIAILRKKAADRGLEL 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 743333906 181 SDECARFLLTRLSRDMRALLDVLDKLDHASMAAQRKLTIPFIKSTLK 227
Cdd:COG0593  187 PDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
 43-227 6.12e-38

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 131.64  E-value: 6.12e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  43 YLCGLGDSGKSHLLYATCIKAQERGLSNMLL---SMREVIDFGPMVldglealDVLCIDDVHLVagNDAWEKALFNFFNR 119
Cdd:PRK08903  46 YLWGEAGSGRSHLLQALVADASYGGRNARYLdaaSPLLAFDFDPEA-------ELYAVDDVERL--DDAQQIALFNLFNR 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906 120 F-NEPGKMLVVTADLLPSMLNISlPDLESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRA 198
Cdd:PRK08903 117 VrAHGQGALLVAGPAAPLALPLR-EDLRTRLGWGLVYELKPLSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPS 195

                        170       180
                 ....*....|....*....|....*....
gi 743333906 199 LLDVLDKLDHASMAAQRKLTIPFIKSTLK 227
Cdd:PRK08903 196 LMALLDALDRYSLEQKRPVTLPLLREMLA 224
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
12-227 6.88e-18

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 81.42  E-value: 6.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  12 TFASYFGGEDSLEVNHLKDSFSKLAK-----TFQYTYLCGLGDSGKSHLLYATCIKAQERGLSNMLLS-------MREVI 79
Cdd:PRK12422 109 TFANFLVTPENDLPHRILQEFTKVSEqgkgfPFNPIYLFGPEGSGKTHLMQAAVHALRESGGKILYVRselftehLVSAI 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  80 DFGPMVL--DGLEALDVLCIDDVHLVAGNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMLNISLPDLESRLTWGTTFQI 157
Cdd:PRK12422 189 RSGEMQRfrQFYRNVDALFIEDIEVFSGKGATQEEFFHTFNSLHTEGKLIVISSTCAPQDLKAMEERLISRFEWGIAIPL 268

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 743333906 158 RSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKLD---HASMAAQRKLTIPFIKSTLK 227
Cdd:PRK12422 269 HPLTKEGLRSFLERKAEALSIRIEETALDFLIEALSSNVKSLLHALTLLAkrvAYKKLSHQLLYVDDIKALLH 341
Bac_DnaA pfam00308
Bacterial dnaA protein;
51-206 4.90e-16

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 73.90  E-value: 4.90e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   51 GKSHLLYATCIKAQE--RGLSNMLLSMREVI-DFGPMVLDG--------LEALDVLCIDDVHLVAGNDAWEKALFNFFNR 119
Cdd:pfam00308  46 GKTHLLHAIGNYALQnaPNLRVVYLTAEEFLnDFVDAIRDNktnqfkekYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNA 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  120 FNEPGKMLVVTADLLPSMLNiSLPD-LESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRA 198
Cdd:pfam00308 126 LHESGKQIVFSSDRPPKELE-ELEDrLRSRFQWGLVTDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRE 204


                  ....*...
gi 743333906  199 LLDVLDKL 206
Cdd:pfam00308 205 LEGALNRL 212
PRK06620 PRK06620
hypothetical protein; Validated
 39-227 2.70e-15

hypothetical protein; Validated


Pssm-ID: 168630  Cd Length: 214  Bit Score: 71.80  E-value: 2.70e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  39 FQYTYL-CGLGDSGKSHLlyatcIKAQERgLSNMLLsMREvIDFGPMVLdglEALDVLCIDDVhlvagnDAW-EKALFNF 116
Cdd:PRK06620  43 YKFTLLiKGPSSSGKTYL-----TKIWQN-LSNAYI-IKD-IFFNEEIL---EKYNAFIIEDI------ENWqEPALLHI 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906 117 FNRFNEPGKMLVVTADLLPSmlNISLPDLESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDM 196
Cdd:PRK06620 106 FNIINEKQKYLLLTSSDKSR--NFTLPDLSSRIKSVLSILLNSPDDELIKILIFKHFSISSVTISRQIIDFLLVNLPREY 183

                        170       180       190
                 ....*....|....*....|....*....|.
gi 743333906 197 RALLDVLDKLDHASMAAQRKLTIPFIKSTLK 227
Cdd:PRK06620 184 SKIIEILENINYFALISKRKITISLVKEVLN 214
PRK09087 PRK09087
hypothetical protein; Validated
 44-226 2.93e-15

hypothetical protein; Validated


Pssm-ID: 169652 [Multi-domain]  Cd Length: 226  Bit Score: 72.01  E-value: 2.93e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  44 LCGLGDSGKSHLLYATCIKAqerglsNMLLSMREVIdfGPMVLDGLEALDVLcIDDVHLVAGNDAwekALFNFFNRFNEP 123
Cdd:PRK09087  49 LAGPVGSGKTHLASIWREKS------DALLIHPNEI--GSDAANAAAEGPVL-IEDIDAGGFDET---GLFHLINSVRQA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906 124 GKMLVVTADLLPSMLNISLPDLESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVL 203
Cdd:PRK09087 117 GTSLLMTSRLWPSSWNVKLPDLKSRLKAATVVEIGEPDDALLSQVIFKLFADRQLYVDPHVVYYLVSRMERSLFAAQTIV 196

                        170       180
                 ....*....|....*....|...
gi 743333906 204 DKLDHASMAAQRKLTIPFIKSTL 226
Cdd:PRK09087 197 DRLDRLALERKSRITRALAAEVL 219
dnaA PRK00149
chromosomal replication initiator protein DnaA;
92-227 4.45e-15

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 73.25  E-value: 4.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  92 LDVLCIDDVHLVAGNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMlnisLPDLE----SRLTWGTTFQIRSMSDDDKAQ 167
Cdd:PRK00149 163 VDVLLIDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPPKE----LPGLEerlrSRFEWGLTVDIEPPDLETRIA 238

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 743333906 168 ALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKLD-HASMaAQRKLTIPFIKSTLK 227
Cdd:PRK00149 239 ILKKKAEEEGIDLPDEVLEFIAKNITSNVRELEGALNRLIaYASL-TGKPITLELAKEALK 298
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 51-227 1.67e-13

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 68.71  E-value: 1.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906   51 GKSHLLYATCIKAQER--GLSNMLLS----MREVIDFgpmVLDG--------LEALDVLCIDDVHLVAGNDAWEKALFNF 116
Cdd:TIGR00362 149 GKTHLLHAIGNEILENnpNAKVLYVSsekfTNDFVNA---LRNNkmeefkekYRSVDLLLIDDIQFLAGKERTQEEFFHT 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  117 FNRFNEPGKMLVVTADLLPSMLNiSLPD-LESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRD 195
Cdd:TIGR00362 226 FNALHENNKQIVLTSDRPPKELP-GLEDrLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSN 304

                         170       180       190
                  ....*....|....*....|....*....|...
gi 743333906  196 MRALLDVLDKLD-HASMaAQRKLTIPFIKSTLK 227
Cdd:TIGR00362 305 VRELEGALNRLLaYASL-TGKPITLELAKEALK 336
dnaA PRK14086
chromosomal replication initiator protein DnaA;
36-199 3.02e-09

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 56.37  E-value: 3.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906  36 AKTFQYTYLCGLGDSGKSHLLYATCIKAQE--RGLSNMLLSMREVI-DFGPMVLDG--------LEALDVLCIDDVHLVA 104
Cdd:PRK14086 311 AKAYNPLFIYGESGLGKTHLLHAIGHYARRlyPGTRVRYVSSEEFTnEFINSIRDGkgdsfrrrYREMDILLVDDIQFLE 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743333906 105 GNDAWEKALFNFFNRFNEPGKMLVVTADLLPSMLnISLPD-LESRLTWGTTFQIRSMSDDDKAQALVKRAHMRGLELSDE 183
Cdd:PRK14086 391 DKESTQEEFFHTFNTLHNANKQIVLSSDRPPKQL-VTLEDrLRNRFEWGLITDVQPPELETRIAILRKKAVQEQLNAPPE 469

                        170
                 ....*....|....*.
gi 743333906 184 CARFLLTRLSRDMRAL 199
Cdd:PRK14086 470 VLEFIASRISRNIREL 485
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
140-206 2.54e-03

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 38.31  E-value: 2.54e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 743333906 140 ISLPDLESRLTW-------GTTFQIRSMSDDDKAQALVKRAHMRGLELSDECARFLLTRLSRDMRALLDVLDKL 206
Cdd:COG1466   99 LTAGKLDKRKKLfkalekaGVVVECYPLKERELPAWIRQRLKAAGLRIDPDAAQLLAERVGGDLLALAQELEKL 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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