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Conserved domains on  [gi|767073368|gb|KJF94899|]
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chemotaxis protein [Photobacterium leiognathi]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
139-676 2.47e-69

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 235.69  E-value: 2.47e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 139 IYSIQKQIIQNNLKLASERATMNYAVSSVRSEMSRVGISLYAGNDYAMSNVTNFLNHAVELGGNLMLLLTEPDLIKAKAI 218
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 219 AKDLKRTNLAGMNYAWDELVRTNAAIDDFSSLTVPFEMVKKLFAKQGFIERYLHVQQLNEEQAVKYAEVKHQTGQIMDLL 298
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 299 LVITQQSHQLIEKGEndfmhASNDARHIFLVFSIIGLLISVLAGMWISRVVKKSIDHISQVVNKISDGDLTVKANTNGAS 378
Cdd:COG0840  161 AALAALLEAAALALA-----AAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKD 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 379 EFAQLGQVLNDLCEHDRESLQQLITNSDELTRAAELSMQASSTSRIALQNQSDELNVVTTSMTHLEESIREISKSSSDSE 458
Cdd:COG0840  236 EIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAA 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 459 KQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQG 538
Cdd:COG0840  316 ELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAG 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 539 RGFAVVADEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQMVTI 618
Cdd:COG0840  396 RGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEI 475

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767073368 619 AVATQQQERASQDVAHNLEQVANRAQHNNRQLDTLVDEAERVAVIAQQQQGMLSRYHL 676
Cdd:COG0840  476 AAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
139-676 2.47e-69

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 235.69  E-value: 2.47e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 139 IYSIQKQIIQNNLKLASERATMNYAVSSVRSEMSRVGISLYAGNDYAMSNVTNFLNHAVELGGNLMLLLTEPDLIKAKAI 218
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 219 AKDLKRTNLAGMNYAWDELVRTNAAIDDFSSLTVPFEMVKKLFAKQGFIERYLHVQQLNEEQAVKYAEVKHQTGQIMDLL 298
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 299 LVITQQSHQLIEKGEndfmhASNDARHIFLVFSIIGLLISVLAGMWISRVVKKSIDHISQVVNKISDGDLTVKANTNGAS 378
Cdd:COG0840  161 AALAALLEAAALALA-----AAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKD 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 379 EFAQLGQVLNDLCEHDRESLQQLITNSDELTRAAELSMQASSTSRIALQNQSDELNVVTTSMTHLEESIREISKSSSDSE 458
Cdd:COG0840  236 EIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAA 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 459 KQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQG 538
Cdd:COG0840  316 ELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAG 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 539 RGFAVVADEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQMVTI 618
Cdd:COG0840  396 RGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEI 475

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767073368 619 AVATQQQERASQDVAHNLEQVANRAQHNNRQLDTLVDEAERVAVIAQQQQGMLSRYHL 676
Cdd:COG0840  476 AAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 417-675 2.52e-47

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 167.85  E-value: 2.52e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   417 QASSTSRIALQNQSDELNVVTTSMTHLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRM 496
Cdd:smart00283   4 EAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSAV 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   497 QQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADDV 576
Cdd:smart00283  84 EELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   577 NDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQMVTIAVATQQQERASQDVAHNLEQVANRAQHNNRQLDTLVDE 656
Cdd:smart00283 164 VAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISAA 243

                          250
                   ....*....|....*....
gi 767073368   657 AERVAVIAQQQQGMLSRYH 675
Cdd:smart00283 244 AEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 441-640 3.83e-43

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 154.32  E-value: 3.83e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 441 THLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKEITEVVELISSIANNT 520
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 521 NLLALNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSRKEMMSSIERSSDVQNA 600
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 767073368 601 INLINNTISDINQQMVTIAVATQQQERASQDVAHNLEQVA 640
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 496-640 3.91e-30

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 116.76  E-value: 3.91e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368  496 MQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADD 575
Cdd:pfam00015  25 MEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTND 104

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767073368  576 VNDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQMVTIAVATQQQERASQDVAHNLEQVA 640
Cdd:pfam00015 105 STASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMD 169
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 314-673 6.68e-26

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 112.41  E-value: 6.68e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 314 NDFMHASNDARHIFLVFSIIGL-LISVLAGMW--ISRVVKKSIDHISQVVNKISDGDLTVKANTNGASEFAQLGQVLNdl 390
Cdd:PRK15048 178 DIVTDNADDYRFAQWQLAVIALvVVLILLVAWygIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVS-- 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 391 ceHDRESLQQLITNSDELTRAAelsmqASSTSRIALQN---------QSDELNVVTTSMTHLEESIREISKSSSDSEKQA 461
Cdd:PRK15048 256 --HMQRSLTDTVTHVREGSDAI-----YAGTREIAAGNtdlssrteqQASALEETAASMEQLTATVKQNADNARQASQLA 328

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 462 QKAQQLALNGVGIIEcstqGLLaleeqfaineKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGF 541
Cdd:PRK15048 329 QSASDTAQHGGKVVD----GVV----------KTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGF 394

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 542 AVVADEVRQLASETNQQTESIRNTItalhkaaDDVndamlVSRKEMMSSIERSSDvqNAINLINNTISDINQQMVTIAVA 621
Cdd:PRK15048 395 AVVAGEVRNLASRSAQAAKEIKALI-------EDS-----VSRVDTGSVLVESAG--ETMNNIVNAVTRVTDIMGEIASA 460

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767073368 622 TQQQERASQDVAHNLEQVANRAQHNNrqldTLVDEAERVAVIAQQQQGMLSR 673
Cdd:PRK15048 461 SDEQSRGIDQVALAVSEMDRVTQQNA----SLVQESAAAAAALEEQASRLTQ 508
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 426-679 1.94e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   426 LQNQSDELNVVTTSMTHLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKE 505
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   506 IT-EVVELISSIAnnTNLLALNAAIEAARAGEQGRgfavvaDEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSR 584
Cdd:TIGR02168  752 LSkELTELEAEIE--ELEERLEEAEEELAEAEAEI------EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   585 KEMMSSIERSSDVQNAINLINNTISDINQQMVTIAVA----TQQQERASQDVAHNLEQVA------NRAQHNNRQLDTLV 654
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEieelEELIEELESELEALLNERAsleealALLRSELEELSEEL 903

                          250       260
                   ....*....|....*....|....*....
gi 767073368   655 DEAERVAVIAQQQ----QGMLSRYHLVVE 679
Cdd:TIGR02168  904 RELESKRSELRREleelREKLAQLELRLE 932
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
139-676 2.47e-69

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 235.69  E-value: 2.47e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 139 IYSIQKQIIQNNLKLASERATMNYAVSSVRSEMSRVGISLYAGNDYAMSNVTNFLNHAVELGGNLMLLLTEPDLIKAKAI 218
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 219 AKDLKRTNLAGMNYAWDELVRTNAAIDDFSSLTVPFEMVKKLFAKQGFIERYLHVQQLNEEQAVKYAEVKHQTGQIMDLL 298
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 299 LVITQQSHQLIEKGEndfmhASNDARHIFLVFSIIGLLISVLAGMWISRVVKKSIDHISQVVNKISDGDLTVKANTNGAS 378
Cdd:COG0840  161 AALAALLEAAALALA-----AAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKD 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 379 EFAQLGQVLNDLCEHDRESLQQLITNSDELTRAAELSMQASSTSRIALQNQSDELNVVTTSMTHLEESIREISKSSSDSE 458
Cdd:COG0840  236 EIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAA 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 459 KQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQG 538
Cdd:COG0840  316 ELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAG 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 539 RGFAVVADEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQMVTI 618
Cdd:COG0840  396 RGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEI 475

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767073368 619 AVATQQQERASQDVAHNLEQVANRAQHNNRQLDTLVDEAERVAVIAQQQQGMLSRYHL 676
Cdd:COG0840  476 AAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 417-675 2.52e-47

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 167.85  E-value: 2.52e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   417 QASSTSRIALQNQSDELNVVTTSMTHLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRM 496
Cdd:smart00283   4 EAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSAV 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   497 QQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADDV 576
Cdd:smart00283  84 EELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   577 NDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQMVTIAVATQQQERASQDVAHNLEQVANRAQHNNRQLDTLVDE 656
Cdd:smart00283 164 VAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISAA 243

                          250
                   ....*....|....*....
gi 767073368   657 AERVAVIAQQQQGMLSRYH 675
Cdd:smart00283 244 AEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 441-640 3.83e-43

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 154.32  E-value: 3.83e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 441 THLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKEITEVVELISSIANNT 520
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 521 NLLALNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSRKEMMSSIERSSDVQNA 600
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 767073368 601 INLINNTISDINQQMVTIAVATQQQERASQDVAHNLEQVA 640
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 496-640 3.91e-30

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 116.76  E-value: 3.91e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368  496 MQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADD 575
Cdd:pfam00015  25 MEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTND 104

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767073368  576 VNDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQMVTIAVATQQQERASQDVAHNLEQVA 640
Cdd:pfam00015 105 STASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMD 169
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 314-673 6.68e-26

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 112.41  E-value: 6.68e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 314 NDFMHASNDARHIFLVFSIIGL-LISVLAGMW--ISRVVKKSIDHISQVVNKISDGDLTVKANTNGASEFAQLGQVLNdl 390
Cdd:PRK15048 178 DIVTDNADDYRFAQWQLAVIALvVVLILLVAWygIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVS-- 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 391 ceHDRESLQQLITNSDELTRAAelsmqASSTSRIALQN---------QSDELNVVTTSMTHLEESIREISKSSSDSEKQA 461
Cdd:PRK15048 256 --HMQRSLTDTVTHVREGSDAI-----YAGTREIAAGNtdlssrteqQASALEETAASMEQLTATVKQNADNARQASQLA 328

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 462 QKAQQLALNGVGIIEcstqGLLaleeqfaineKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGF 541
Cdd:PRK15048 329 QSASDTAQHGGKVVD----GVV----------KTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGF 394

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 542 AVVADEVRQLASETNQQTESIRNTItalhkaaDDVndamlVSRKEMMSSIERSSDvqNAINLINNTISDINQQMVTIAVA 621
Cdd:PRK15048 395 AVVAGEVRNLASRSAQAAKEIKALI-------EDS-----VSRVDTGSVLVESAG--ETMNNIVNAVTRVTDIMGEIASA 460

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767073368 622 TQQQERASQDVAHNLEQVANRAQHNNrqldTLVDEAERVAVIAQQQQGMLSR 673
Cdd:PRK15048 461 SDEQSRGIDQVALAVSEMDRVTQQNA----SLVQESAAAAAALEEQASRLTQ 508
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
303-645 1.29e-23

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 105.15  E-value: 1.29e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 303 QQSHQLIEKGENDFMHASNDARHIFLVFSIIGLLISVLAGMWISRVVKKSIDHISQVVNKISDGDLTVKANTNGASEFAQ 382
Cdd:PRK09793 168 LEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIAAGNLARPIAVYGRNEITA 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 383 LGQVLNDLCEHDRESLQQLITNSDEL-TRAAELSMQASSTSRIALQnQSDELNVVTTSMTHLEESIREISKSSSDSEKQA 461
Cdd:PRK09793 248 IFASLKTMQQALRGTVSDVRKGSQEMhIGIAEIVAGNNDLSSRTEQ-QAASLAQTAASMEQLTATVGQNADNARQASELA 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 462 QKAQQLALNGvgiiecstqgllalEEQFAINEKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGF 541
Cdd:PRK09793 327 KNAATTAQAG--------------GVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGF 392

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 542 AVVADEVRQLASETNQQTESIR----NTITALHKAADDVNDAMlVSRKEMMSSIERSSDVQNAINLINNT----ISDINQ 613
Cdd:PRK09793 393 AVVAGEVRNLASRSAQAAKEIKglieESVNRVQQGSKLVNNAA-ATMTDIVSSVTRVNDIMGEIASASEEqrrgIEQVAQ 471

                        330       340       350
                 ....*....|....*....|....*....|..
gi 767073368 614 QMVTIAVATQQQERASQDVAHNLEQVANRAQH 645
Cdd:PRK09793 472 AVSQMDQVTQQNASLVEEAAVATEQLANQADH 503
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
303-673 3.22e-21

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 98.10  E-value: 3.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 303 QQSHQLIEKGENDFMHASNDArhIFLVFSIIGLLISVLAGMW--ISRVVKKSIDHISQVVNKISDGDLTVKANTNGASEF 380
Cdd:PRK15041 172 EQNDRLYDIAVSDNNASYSQA--MWILVGVMIVVLAVIFAVWfgIKASLVAPMNRLIDSIRHIAGGDLVKPIEVDGSNEM 249

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 381 AQLGQVLNDLCEHDRESLQQLITNSDEL-TRAAELSMQASSTSRIALQnQSDELNVVTTSMTHLEESIREISKSSSDSEK 459
Cdd:PRK15041 250 GQLAESLRHMQGELMRTVGDVRNGANAIySGASEIATGNNDLSSRTEQ-QAASLEETAASMEQLTATVKQNAENARQASH 328

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 460 QAQKAQQLALNGVGIIECSTQgllaleeqfainekRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGR 539
Cdd:PRK15041 329 LALSASETAQRGGKVVDNVVQ--------------TMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR 394

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 540 GFAVVADEVRQLASETNQQTESIRNTIT-ALHKAadDVNDAMLVSRKEMM----SSIERSSDVQNAINLINNTIS-DINQ 613
Cdd:PRK15041 395 GFAVVAGEVRNLAQRSAQAAREIKSLIEdSVGKV--DVGSTLVESAGETMaeivSAVTRVTDIMGEIASASDEQSrGIDQ 472

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 614 qmVTIAVAtqQQERASQDVAHNLEQVANRAQHNNRQLDTLvdeAERVAVIAQQQQGMLSR 673
Cdd:PRK15041 473 --VGLAVA--EMDRVTQQNAALVEESAAAAAALEEQASRL---TEAVAVFRIQQQQQQQR 525
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 243-584 5.30e-06

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 49.50  E-value: 5.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 243 AIDDFSSLTVPFEMVKKLFAKQGFIERYLHVQQLNEEQAVKYAEVKHQTGQIMDLLLVITQQSHQLIEKGENDFMHASND 322
Cdd:COG3850   36 LLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLLAALLSLLLLLLLLLLLLLLLLLLLLAAAI 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 323 ARHIFLVFSIIGLLISVLAGMWISRVVKKSIDHISQVVNKISDGDLTVKANTNGASEFAQLGQVLNDLCEHDRESLQQLI 402
Cdd:COG3850  116 NRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELE 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 403 TNSDELTRAAELSMQASSTSRIALQNQSDELNVVTTSMTHLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGL 482
Cdd:COG3850  196 EEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLA 275

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 483 LALEEQFAINEKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESI 562
Cdd:COG3850  276 SALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEA 355

                        330       340
                 ....*....|....*....|..
gi 767073368 563 RNTITALHKAADDVNDAMLVSR 584
Cdd:COG3850  356 AAAGAALAAAAAAAGLARALAQ 377
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 426-679 1.94e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   426 LQNQSDELNVVTTSMTHLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKE 505
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   506 IT-EVVELISSIAnnTNLLALNAAIEAARAGEQGRgfavvaDEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSR 584
Cdd:TIGR02168  752 LSkELTELEAEIE--ELEERLEEAEEELAEAEAEI------EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368   585 KEMMSSIERSSDVQNAINLINNTISDINQQMVTIAVA----TQQQERASQDVAHNLEQVA------NRAQHNNRQLDTLV 654
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEieelEELIEELESELEALLNERAsleealALLRSELEELSEEL 903

                          250       260
                   ....*....|....*....|....*....
gi 767073368   655 DEAERVAVIAQQQ----QGMLSRYHLVVE 679
Cdd:TIGR02168  904 RELESKRSELRREleelREKLAQLELRLE 932
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
136-667 3.21e-05

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 47.03  E-value: 3.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 136 AFDIYSIQKQIIQNNLKLASERATMNYAVSSVRSEMSRVGISLYAGNDYAMSNVTNFLNHAVELGGNLMLLLTEPDLIKA 215
Cdd:COG2770   23 GALLVLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 216 KAIAKDLKRTNLAGMNYAWDELVRTNAAIDDFSSLTVPFEMVKKLFAKQGFIERYLHVQQLNEEQAVKYAEVKHQTGQIM 295
Cdd:COG2770  103 LLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAA 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 296 DLLLVITQQSHQLIEKGENDFMHASNDARHIFLVFSIIGLLISVLAGMWISRVVKKSIDHISQVVNKISDGDLTVKANTN 375
Cdd:COG2770  183 IAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVS 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 376 GASEFAQLGQVLNDLCEHDRESLQQLITNSDELTRAAELSMQASSTSRIALQNQSDELNVVTTSMTHLEESIREISKSSS 455
Cdd:COG2770  263 RKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLL 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 456 DSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDNYVKEITEVVELISSIANNTNLLALNAAIEAARAG 535
Cdd:COG2770  343 LLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALL 422

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 536 EQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSRKEMMSSIERSSDVQNAINLINNTISDINQQM 615
Cdd:COG2770  423 ALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAA 502

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767073368 616 VTIAVATQQQERASQDVAHNLEQVANRAQHNNRQLDTLVDEAERVAVIAQQQ 667
Cdd:COG2770  503 EELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLAL 554
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 425-673 1.12e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 1.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 425 ALQNQSDELNVVTTSMTHLEESIREISKSSSDSEKQAQKAQQLALNGVGIIECSTQGLLALEEQFAINEKRMQQLDnyvk 504
Cdd:COG1196  247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE---- 322

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 505 eiTEVVELISSIANNTNLLAlNAAIEAARAGEQGRGFAVVADEVRQLASETNQQTESIRNTITALHKAADDVNDAMLVSR 584
Cdd:COG1196  323 --EELAELEEELEELEEELE-ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767073368 585 KEMMSSIERSSDVQNAINLINNTISDINQQMVTIAVATQQQERASQDVAHNLEQVANRAQHNNRQLDTLVDEAERVAVIA 664
Cdd:COG1196  400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479


                 ....*....
gi 767073368 665 QQQQGMLSR 673
Cdd:COG1196  480 AELLEELAE 488
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
347-403 1.16e-03

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 37.23  E-value: 1.16e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767073368   347 RVVKKSIDHISQVVNKISDGDLTVKANTNGASEFAQLGQVLNDLcehdRESLQQLIT 403
Cdd:smart00304   1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEM----ADRLEETIA 53
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 351-389 1.36e-03

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 37.04  E-value: 1.36e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 767073368 351 KSIDHISQVVNKISDGDLTVKANTNGASEFAQLGQVLND 389
Cdd:cd06225    2 RPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQ 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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