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Conserved domains on  [gi|818242663|gb|KKP29756|]
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Ribosomal protein S18 alanine N-acetyltransferase [candidate division TM6 bacterium GW2011_GWF2_30_66]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10456837)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  15581578|10940244|9175471|27367672|26818562
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 64-175 3.27e-16

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


:

Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 71.01  E-value: 3.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663   64 WLVASSREEYSPDFMLKNRAYDRDPAHFgkldIKVLRENNKLAGFTAYF--NKKIYEGFLLYVGVDRDFRGEGYGEKLTN 141
Cdd:pfam00583   7 LLSEEFPEPWPDEPLDLLEDWDEDASEG----FFVAEEDGELVGFASLSiiDDEPPVGEIEGLAVAPEYRGKGIGTALLQ 82

                          90       100       110
                  ....*....|....*....|....*....|....
gi 818242663  142 YAVEDMFANGCNIVKLITRTENIKARSLYKKLGF 175
Cdd:pfam00583  83 ALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 64-175 3.27e-16

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 71.01  E-value: 3.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663   64 WLVASSREEYSPDFMLKNRAYDRDPAHFgkldIKVLRENNKLAGFTAYF--NKKIYEGFLLYVGVDRDFRGEGYGEKLTN 141
Cdd:pfam00583   7 LLSEEFPEPWPDEPLDLLEDWDEDASEG----FFVAEEDGELVGFASLSiiDDEPPVGEIEGLAVAPEYRGKGIGTALLQ 82

                          90       100       110
                  ....*....|....*....|....*....|....
gi 818242663  142 YAVEDMFANGCNIVKLITRTENIKARSLYKKLGF 175
Cdd:pfam00583  83 ALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 107-190 2.70e-15

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 67.76  E-value: 2.70e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663 107 GF-TAYFNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKLGFEETLVDGGYV 185
Cdd:COG0456    1 GFaLLGLVDGGDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEEVGERPNYY 80


                 ....*
gi 818242663 186 YYTKY 190
Cdd:COG0456   81 GDDAL 85
rimI TIGR01575
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ...
 94-177 2.94e-11

ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273701 [Multi-domain]  Cd Length: 131  Bit Score: 58.11  E-value: 2.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663   94 LDIKVLRENNKLAGFTAYfNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKL 173
Cdd:TIGR01575  31 LCYLLARIGGKVVGYAGV-QIVLDEAHILNIAVKPEYQGQGIGRALLRELIDEAKGRGVNEIFLEVRVSNIAAQALYKKL 109


                  ....
gi 818242663  174 GFEE 177
Cdd:TIGR01575 110 GFNE 113
PRK03624 PRK03624
putative acetyltransferase; Provisional
 119-177 4.90e-09

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 52.62  E-value: 4.90e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 818242663 119 GFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKLGFEE 177
Cdd:PRK03624  69 GWAYYLAVHPDFRGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYEE 127
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 98-157 9.41e-07

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 44.57  E-value: 9.41e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818242663  98 VLRENNKLAGFTAY--FNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKL 157
Cdd:cd04301    3 VAEDDGEIVGFASLspDGSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRL 64
 
Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 64-175 3.27e-16

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 71.01  E-value: 3.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663   64 WLVASSREEYSPDFMLKNRAYDRDPAHFgkldIKVLRENNKLAGFTAYF--NKKIYEGFLLYVGVDRDFRGEGYGEKLTN 141
Cdd:pfam00583   7 LLSEEFPEPWPDEPLDLLEDWDEDASEG----FFVAEEDGELVGFASLSiiDDEPPVGEIEGLAVAPEYRGKGIGTALLQ 82

                          90       100       110
                  ....*....|....*....|....*....|....
gi 818242663  142 YAVEDMFANGCNIVKLITRTENIKARSLYKKLGF 175
Cdd:pfam00583  83 ALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 107-190 2.70e-15

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 67.76  E-value: 2.70e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663 107 GF-TAYFNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKLGFEETLVDGGYV 185
Cdd:COG0456    1 GFaLLGLVDGGDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEEVGERPNYY 80


                 ....*
gi 818242663 186 YYTKY 190
Cdd:COG0456   81 GDDAL 85
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
124-178 1.14e-11

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 58.00  E-value: 1.14e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 818242663 124 VGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKLGFEET 178
Cdd:COG3393   21 VYTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGFRPV 75
rimI TIGR01575
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ...
 94-177 2.94e-11

ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273701 [Multi-domain]  Cd Length: 131  Bit Score: 58.11  E-value: 2.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663   94 LDIKVLRENNKLAGFTAYfNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKL 173
Cdd:TIGR01575  31 LCYLLARIGGKVVGYAGV-QIVLDEAHILNIAVKPEYQGQGIGRALLRELIDEAKGRGVNEIFLEVRVSNIAAQALYKKL 109


                  ....
gi 818242663  174 GFEE 177
Cdd:TIGR01575 110 GFNE 113
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 98-178 3.25e-10

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 55.38  E-value: 3.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663  98 VLRENNKLAGFTAYFNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTEnikARSLYKKLGFEE 177
Cdd:COG1246   32 VAEEDGEIVGCAALHPLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSA---AIHFYEKLGFEE 108


                 .
gi 818242663 178 T 178
Cdd:COG1246  109 I 109
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 98-177 3.67e-10

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 54.00  E-value: 3.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663   98 VLRENNKLAGF-TAYFNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAvedMFANGCNIVKLITRTENIKARSLYKKLGFE 176
Cdd:pfam13508   7 VAEDDGKIVGFaALLPLDDEGALAELRLAVHPEYRGQGIGRALLEAA---EAAAKEGGIKLLELETTNRAAAFYEKLGFE 83


                  .
gi 818242663  177 E 177
Cdd:pfam13508  84 E 84
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
50-178 4.26e-10

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 55.77  E-value: 4.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663  50 DAESILKIfdkdWYWLVASSREEY-----SPDFMLKNRAYDRDPAHFgkldIKVLRENNKLAGFTAYFNKKIYEGF---- 120
Cdd:COG1247   11 DAPAIAAI----YNEAIAEGTATFeteppSEEEREAWFAAILAPGRP----VLVAEEDGEVVGFASLGPFRPRPAYrgta 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 818242663 121 LLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKLGFEET 178
Cdd:COG1247   83 EESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEV 140
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 50-185 2.58e-09

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 53.85  E-value: 2.58e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663  50 DAESILKIFDKD----WYWLVASSREEYspDFMLKNRAYDRDPAHFGKLDIkVLRENNKLAGFTAYFNKKIYEGFL-LYV 124
Cdd:COG1670   17 DAEALAELLNDPevarYLPGPPYSLEEA--RAWLERLLADWADGGALPFAI-EDKEDGELIGVVGLYDIDRANRSAeIGY 93

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818242663 125 GVDRDFRGEGYG----EKLTNYAVEDMfanGCNIVKLITRTENIKARSLYKKLGFEET-------LVDGGYV 185
Cdd:COG1670   94 WLAPAYWGKGYAtealRALLDYAFEEL---GLHRVEAEVDPDNTASIRVLEKLGFRLEgtlrdalVIDGRYR 162
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
50-178 3.06e-09

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 53.17  E-value: 3.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663  50 DAESILKIFDKDWywlvassREEYSPDFMLKNRAYDRDPAHFgkldikVLRENNKLAGFTAYFNKKIYE----GFLLYVG 125
Cdd:COG3153    8 DAEAIAALLRAAF-------GPGREAELVDRLREDPAAGLSL------VAEDDGEIVGHVALSPVDIDGegpaLLLGPLA 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 818242663 126 VDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITrteNIKARSLYKKLGFEET 178
Cdd:COG3153   75 VDPEYRGQGIGRALMRAALEAARERGARAVVLLG---DPSLLPFYERFGFRPA 124
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 78-178 4.77e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 52.36  E-value: 4.77e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663  78 MLKNRAYDRDPAHFgkldiKVLRENNKLAGFTAYfnkKIYEGFLLYVG---VDRDFRGEGYGEKLTNYAVEDMFANGCNI 154
Cdd:COG0454   23 ELKAMEGSLAGAEF-----IAVDDKGEPIGFAGL---RRLDDKVLELKrlyVLPEYRGKGIGKALLEALLEWARERGCTA 94

                         90       100
                 ....*....|....*....|....
gi 818242663 155 VKLITRTENIKARSLYKKLGFEET 178
Cdd:COG0454   95 LELDTLDGNPAAIRFYERLGFKEI 118
PRK03624 PRK03624
putative acetyltransferase; Provisional
 119-177 4.90e-09

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 52.62  E-value: 4.90e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 818242663 119 GFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKLGFEE 177
Cdd:PRK03624  69 GWAYYLAVHPDFRGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYEE 127
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
83-178 5.16e-07

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 46.72  E-value: 5.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663  83 AYDRDPAHFgkldikVLRENNKLAGFTAYFNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTE 162
Cdd:COG2153   29 GKDEDARHL------LAYDDGELVATARLLPPGDGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARERGARRIVLSAQAH 102

                         90
                 ....*....|....*.
gi 818242663 163 nikARSLYKKLGFEET 178
Cdd:COG2153  103 ---AVGFYEKLGFVPV 115
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 99-177 7.44e-07

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 46.46  E-value: 7.44e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 818242663  99 LRENNKLAGFtAYFNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKLITRTENIKARSLYKKLGFEE 177
Cdd:PRK09491  45 LTVNGQMAAF-AITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFNE 122
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 98-157 9.41e-07

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 44.57  E-value: 9.41e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818242663  98 VLRENNKLAGFTAY--FNKKIYEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGCNIVKL 157
Cdd:cd04301    3 VAEDDGEIVGFASLspDGSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRL 64
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 117-177 1.30e-04

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 39.24  E-value: 1.30e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 818242663  117 YEGFLLYVGVDRDFRGEGYGEKLTNYAVEDMFANGcNIVKLITRTENIKARSLYKKLGFEE 177
Cdd:pfam08445  20 PGGELGALQTLPEHRRRGLGSRLVAALARGIAERG-ITPFAVVVAGNTPSRRLYEKLGFRK 79
YidJ COG2388
Predicted acetyltransferase, GNAT superfamily [General function prediction only];
98-151 2.55e-04

Predicted acetyltransferase, GNAT superfamily [General function prediction only];


Pssm-ID: 441953 [Multi-domain]  Cd Length: 88  Bit Score: 38.21  E-value: 2.55e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 818242663  98 VLRENNKLAGFTAY--FNKKIYegfLLYVGVDRDFRGEGYGEKLTNYAVEDMFANG 151
Cdd:COG2388   13 ELEVDGELAGELTYrlEGGVII---ITHTEVPPALRGQGIASALVEAALDDARERG 65
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 98-178 4.29e-04

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 38.79  E-value: 4.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818242663   98 VLRENNKLAGFTA-YFNKKIYegfLLYVgvDRDFRGEGYGEKLTNyAVEDMFANGCNIVKLITRTENIKARSLYKKLGFE 176
Cdd:pfam13673  35 VAFEGGQIVGVIAlRDRGHIS---LLFV--DPDYQGQGIGKALLE-AVEDYAEKDGIKLSELTVNASPYAVPFYEKLGFR 108


                  ..
gi 818242663  177 ET 178
Cdd:pfam13673 109 AT 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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