|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
11-675 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 667.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 11 LSLRVSVVLCTLIISSVIFYneiIIDLPNPHSLRNFPDKLTTQIVDRHGKLLYKIYeDENRTLIKLNDLPPHIKNAFLTA 90
Cdd:COG0744 18 LLLLLAVLVLAALAGLVALY---VADLPDPEELEDLALPQTSTIYDRDGTLIATLG-DENREWVPLDQIPPHLKDAVVAI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 91 EDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGSTITQQLIKNTLLTNEKTITRKIKELILAFQVENIFTKDEIFEMYLN 169
Cdd:COG0744 94 EDRRFYEHGGVDPKGIARALVANLTAGGvVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLN 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 170 QVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPYGeNPELAYTRQKQVLHQMVKNGFLSVDELDLAL 249
Cdd:COG0744 174 TVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYR-NPEAAKERRNLVLDRMVEQGYITQAEADAAK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 250 TVKLEFSSAKTEIN---APHFVMFVKDILTSQLGENIVNHGGLIVTTTLDLELQNLAQKAVTEEVSKlKNFNVSNGAALV 326
Cdd:COG0744 253 AEPLTLVPPPNGAAagkYPYFVDYVRRELEELLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPE-GKPGGLQAALVV 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 327 TNPQTGEILAMVGSKDYfnlnEDGQVNLTT-SLRQPGSSIKPINYALAFEKGLRPSSTIEDKPISFNlvgQGPWVPKNYD 405
Cdd:COG0744 332 VDPKTGEVLAMVGGRDY----GKSQFNRATqAKRQPGSTFKPFVYAAALEQGYTPATTVDDEPVTFP---GGGWSPKNYD 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 406 GRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITtwnEPERYGLSMALGSLEVKMTDLATAYSTFANKGIA 485
Cdd:COG0744 405 GRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT---SPLDPNPSLALGTSEVSPLEMASAYATFANGGVY 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 486 TPLKSIISVKTRESKDLFlascpmqmIADPESatalatdqscskKRAVSPLTAYLITDVLSDNSARtpafGFNSVLNIKP 565
Cdd:COG0744 482 VEPHAITKVTDADGKVLY--------EAKPKC------------EQVISPEVAYLMTDMLQDVVTS----GTGRAARLPG 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 566 AKVAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPMSRVaSGITGASPIWAKIFNQIIEKYPqPKEIAKPDNLISVp 645
Cdd:COG0744 538 RPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGYV-TGGSLPAPIWRDFMEAALEGLP-VEDFPKPSGVVRI- 614
|
650 660 670
....*....|....*....|....*....|
gi 818724561 646 ictltgtltCDGCPTRneyfvKGTEPKVSC 675
Cdd:COG0744 615 ---------DEPSPTP-----SGTEPTETS 630
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
70-628 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 529.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 70 NRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGSTITQQLIKNTLLTNEKTITRKIKEL 148
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRvLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 149 ILAFQVENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPYgENPELAYTRQK 228
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPF-KNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 229 QVLHQMVKNGFLSVDELDLA----LTVKLEFSSAKTEInAPHFVMFVKDILTSQLGENIVNhGGLIVTTTLDLELQNLAQ 304
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAinepIQLYLQTKKSEQYK-APYFVDYVIQELEEEYGEELYT-GGLKIYTTLDLDAQKAAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 305 KAV--TEEVSKLKNFNVSNGAALVTNPQTGEILAMVGSKDYfnlnEDGQVN-LTTSLRQPGSSIKPINYALAFEKGLRPS 381
Cdd:TIGR02074 238 KVLntGLRVAGRRDGDDLQAALVAIDPDTGAVRALVGGRDY----GKSQFNrATQAKRQPGSTFKPFVYAAALEKGLTPA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 382 STIEDKPISFNlvGQGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITTwnePERYGLSMA 461
Cdd:TIGR02074 314 TIVNDEPITYN--GNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITS---PLDPVLSLA 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 462 LGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFlascpmqmiadpesatalatDQSCSKKRAVSPLTAYLI 541
Cdd:TIGR02074 389 LGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIY--------------------ENKPKTTQVISPATAYIM 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 542 TDVLSDnsarTPAFGFNSVLNIKPAKVAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPMSRVASGITGASPIWAKI 621
Cdd:TIGR02074 449 TDMLKG----VVESGTGRSARLPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGGLAAPIWRDF 524
|
....*..
gi 818724561 622 FNQIIEK 628
Cdd:TIGR02074 525 MAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
58-235 |
8.47e-86 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 267.47 E-value: 8.47e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 58 HGKLLYKIYEdENRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDRL-EGGSTITQQLIKNTLLT 136
Cdd:pfam00912 1 DGTLLAELGE-ENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 137 NEKTITRKIKELILAFQVENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPY 216
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*....
gi 818724561 217 gENPELAYTRQKQVLHQMV 235
Cdd:pfam00912 160 -RNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
13-686 |
1.37e-78 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 268.54 E-value: 1.37e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 13 LRVSVVLCTLIISSVIF--YNEIIIDLPNPHSLRNFPDKLTTQIVDRHGKLLYKiYEDENRTLIKLNDLPPHIKNAFLTA 90
Cdd:PRK11636 7 LLILAVCCILLGAGSIYglYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQ-YGEKRRIPLTLDQIPPEMVKAFIAT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 91 EDKDFYHHKGFSPVGLVRAVYKNFTKDRL-EGGSTITQQLIKNTLLTNEKTITRKIKELILAFQVENIFTKDEIFEMYLN 169
Cdd:PRK11636 86 EDSRFYEHHGVDPVGIFRAASVALFSGHAsQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 170 QVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSP-YgeNPELAYTRQKQVLHQMVKNGFLSVDELDLA 248
Cdd:PRK11636 166 KIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPlY--SMDRAVARRNVVLSRMLDEGYITQAQYDQA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 249 LTVKLEFSSAKTEI--NAPHFVMFVKDILTSQLGENIVNHgGLIVTTTLDLELQNLAQKAVTEEV--------------- 311
Cdd:PRK11636 244 RSEPIVANYHAPEIafSAPYLSEMVRQEMYNRYGENAYED-GYRVYTTITRKVQQAAQQAVRNNVldydmrhgyrgpanv 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 312 ---------------SKLKNFNV---------------------SNG--------------------------------- 322
Cdd:PRK11636 323 lwkvgesawdnkkitDTLKALPTygpllpavvtsanpqeatamlADGssvalpmegvrwarpyrsdtqqgptprkvtdvv 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 323 ------------------------AALVT-NPQTGEILAMVGSKDyFNLNEDGQVnlTTSLRQPGSSIKPINYALAFEKG 377
Cdd:PRK11636 403 qtgqqiwvrqvddawwlaqvpdvnSALVSiNPQNGAVMALVGGFD-FNQSKFNRA--TQALRQVGSNIKPFLYTAAMDKG 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 378 LRPSSTIEDKPISFNLVGQGP-WVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITTWN--EPE 454
Cdd:PRK11636 480 LTLASMLNDVPISRWDAGAGSdWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNivHTE 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 455 ryglSMALGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFLA-------SCPMQMI-ADPESATALATD-- 524
Cdd:PRK11636 560 ----SLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAkpkvacpECDIPVIyGDTQKSNVLENDdv 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 525 ----QSCSKKRAVSPLT---------------------------AYLITDVLSDNSARTPAF---GFNSVLNIKPAKVAV 570
Cdd:PRK11636 636 envaTSQEQQNSSVPMPqleqanqalvaqngaqeyaphvintplAFLIKSALNTNIFGEPGWmgtGWRAGRDLKRRDIGG 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 571 KTGTSNDLRDNWTIGYTDTFLVASWVG-NNNNEPMSRV-ASG-----ITG-------ASPIWAKIFNQIIEKYPQpKEIA 636
Cdd:PRK11636 716 KTGTTNSSKDAWFSGYGPGVVTSVWIGfDDHRRDLGRTtASGaikdqISGyeggaksAQPAWDDYMKAALEGVPE-QPLT 794
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 818724561 637 KPDNLISVPICTLTGTLTcDGCPTRNEYFVKGTEPKVSCNPQLVKTILES 686
Cdd:PRK11636 795 PPPGIVTVNIDRSTGKLA-NGGNSREEYFIEGTQPTQQAVHEVGTTIIDN 843
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
11-675 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 667.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 11 LSLRVSVVLCTLIISSVIFYneiIIDLPNPHSLRNFPDKLTTQIVDRHGKLLYKIYeDENRTLIKLNDLPPHIKNAFLTA 90
Cdd:COG0744 18 LLLLLAVLVLAALAGLVALY---VADLPDPEELEDLALPQTSTIYDRDGTLIATLG-DENREWVPLDQIPPHLKDAVVAI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 91 EDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGSTITQQLIKNTLLTNEKTITRKIKELILAFQVENIFTKDEIFEMYLN 169
Cdd:COG0744 94 EDRRFYEHGGVDPKGIARALVANLTAGGvVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLN 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 170 QVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPYGeNPELAYTRQKQVLHQMVKNGFLSVDELDLAL 249
Cdd:COG0744 174 TVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYR-NPEAAKERRNLVLDRMVEQGYITQAEADAAK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 250 TVKLEFSSAKTEIN---APHFVMFVKDILTSQLGENIVNHGGLIVTTTLDLELQNLAQKAVTEEVSKlKNFNVSNGAALV 326
Cdd:COG0744 253 AEPLTLVPPPNGAAagkYPYFVDYVRRELEELLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPE-GKPGGLQAALVV 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 327 TNPQTGEILAMVGSKDYfnlnEDGQVNLTT-SLRQPGSSIKPINYALAFEKGLRPSSTIEDKPISFNlvgQGPWVPKNYD 405
Cdd:COG0744 332 VDPKTGEVLAMVGGRDY----GKSQFNRATqAKRQPGSTFKPFVYAAALEQGYTPATTVDDEPVTFP---GGGWSPKNYD 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 406 GRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITtwnEPERYGLSMALGSLEVKMTDLATAYSTFANKGIA 485
Cdd:COG0744 405 GRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT---SPLDPNPSLALGTSEVSPLEMASAYATFANGGVY 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 486 TPLKSIISVKTRESKDLFlascpmqmIADPESatalatdqscskKRAVSPLTAYLITDVLSDNSARtpafGFNSVLNIKP 565
Cdd:COG0744 482 VEPHAITKVTDADGKVLY--------EAKPKC------------EQVISPEVAYLMTDMLQDVVTS----GTGRAARLPG 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 566 AKVAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPMSRVaSGITGASPIWAKIFNQIIEKYPqPKEIAKPDNLISVp 645
Cdd:COG0744 538 RPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGYV-TGGSLPAPIWRDFMEAALEGLP-VEDFPKPSGVVRI- 614
|
650 660 670
....*....|....*....|....*....|
gi 818724561 646 ictltgtltCDGCPTRneyfvKGTEPKVSC 675
Cdd:COG0744 615 ---------DEPSPTP-----SGTEPTETS 630
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
15-677 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 582.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 15 VSVVLCTLIISSVIFYneIIIDLPNPHSLRNFPDKLTTQIVDRHGKLLYKIYEdENRTLIKLNDLPPHIKNAFLTAEDKD 94
Cdd:COG5009 13 LLLLLGALAVAGLYLY--LSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGE-ERRIPVPIEEIPPLLINAFLAAEDKR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 95 FYHHKGFSPVGLVRAVYKNFTK-DRLEGGSTITQQLIKNTLLTNEKTITRKIKELILAFQVENIFTKDEIFEMYLNQVGF 173
Cdd:COG5009 90 FYEHPGVDPIGIARAAVVNLRTgRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 174 GGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPYgENPELAYTRQKQVLHQMVKNGFLSVDELDLALTVKL 253
Cdd:COG5009 170 GHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPI-RNPERALERRNYVLGRMLELGYITQAEYEAAKAEPL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 254 EFSSAKTEI--NAPHFVMFVKDILTSQLGENIVNHGGLIVTTTLDLELQNLAQKAV----------------------TE 309
Cdd:COG5009 249 TARYHGASAevDAPYFAEMVRRELVERYGEDALYTGGLKVYTTLDPRLQEAAEKALrdgllaydrrhgyrgpeahldlAE 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 310 E--VSKLKNFNVSNG--AALVT---------------------------------------------------------- 327
Cdd:COG5009 329 EdwDEALAEVPDVGDlrPAVVLevddksarvglrdgetgtlpleglkwarpyindnrrgpapksasdvlkpgdvirvrpv 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 328 --------------------NPQTGEILAMVGSKDYfnlnEDGQVNLTT-SLRQPGSSIKPINYALAFEKGLRPSSTIED 386
Cdd:COG5009 409 adggwrlrqipevqgalvalDPHTGAVLALVGGFDF----EQSKFNRATqAKRQPGSSFKPFVYAAALDNGYTPATIIND 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 387 KPISFNL-VGQGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITtwNEPERYgLSMALGSL 465
Cdd:COG5009 485 APIVFDDgGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIY--SKLPPN-LSLALGSG 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 466 EVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFLAS----CPMQMIADPESATALATDQScskKRAVSPLTAYLI 541
Cdd:COG5009 562 EVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADparaCEDCDAAEWDGAEPRLPDPA---EQVIDPRTAYQM 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 542 TDVLSDN-----SARTPAFGfnsvlniKPakVAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPMSRVASGITGASP 616
Cdd:COG5009 639 TSMLRGVvqrgtGRRARALG-------RD--IAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPRSLGRGETGGRAALP 709
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818724561 617 IWAKIFNQIIEKYPqPKEIAKPDNLISVPICTLTGTLTCDGCP-TRNEYFVKGTEPKVSCNP 677
Cdd:COG5009 710 IWIDFMKAALKDKP-EKPFPVPEGIVTVRIDPKTGLLASPGDPdAIFEAFKPGTEPTESASE 770
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
70-628 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 529.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 70 NRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGSTITQQLIKNTLLTNEKTITRKIKEL 148
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRvLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 149 ILAFQVENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPYgENPELAYTRQK 228
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPF-KNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 229 QVLHQMVKNGFLSVDELDLA----LTVKLEFSSAKTEInAPHFVMFVKDILTSQLGENIVNhGGLIVTTTLDLELQNLAQ 304
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAinepIQLYLQTKKSEQYK-APYFVDYVIQELEEEYGEELYT-GGLKIYTTLDLDAQKAAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 305 KAV--TEEVSKLKNFNVSNGAALVTNPQTGEILAMVGSKDYfnlnEDGQVN-LTTSLRQPGSSIKPINYALAFEKGLRPS 381
Cdd:TIGR02074 238 KVLntGLRVAGRRDGDDLQAALVAIDPDTGAVRALVGGRDY----GKSQFNrATQAKRQPGSTFKPFVYAAALEKGLTPA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 382 STIEDKPISFNlvGQGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITTwnePERYGLSMA 461
Cdd:TIGR02074 314 TIVNDEPITYN--GNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITS---PLDPVLSLA 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 462 LGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFlascpmqmiadpesatalatDQSCSKKRAVSPLTAYLI 541
Cdd:TIGR02074 389 LGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIY--------------------ENKPKTTQVISPATAYIM 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 542 TDVLSDnsarTPAFGFNSVLNIKPAKVAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPMSRVASGITGASPIWAKI 621
Cdd:TIGR02074 449 TDMLKG----VVESGTGRSARLPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGGLAAPIWRDF 524
|
....*..
gi 818724561 622 FNQIIEK 628
Cdd:TIGR02074 525 MAEALKN 531
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
11-677 |
4.49e-175 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 519.00 E-value: 4.49e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 11 LSLRVSVVLCTLIISSVIFYneiiidLPNPhslRNFPDKLTTQIVDRHGKLLY-KIYEDENRTL-IKLNDLPPHIKNAFL 88
Cdd:COG4953 12 LALLLALLLLALALWALDRL------FPLP---LLFAVPYSTVVLDRDGTLLRaFLAADGQWRLpVPLDEVSPRYLQALL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 89 TAEDKDFYHHKGFSPVGLVRAVYKNFT-KDRLEGGSTITQQLIKntLLT-NEKTITRKIKELILAFQVENIFTKDEIFEM 166
Cdd:COG4953 83 AYEDRRFYYHPGVNPLALLRAAWQNLRsGRIVSGGSTLTMQVAR--LLEpRPRTLSGKLRQILRALQLERRYSKDEILEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 167 YLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPyGENPELAYTRQKQVLHQMVKNGFLSVDELD 246
Cdd:COG4953 161 YLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRP-DRNPERARAARDRVLARLAEAGVIDAEEAA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 247 LALTVKLEFSSAKTEINAPHFVmfvkDILTSQlgenivNHGGLIVTTTLDLELQNLAQKAVTEEVSKLKNFNVSNGAALV 326
Cdd:COG4953 240 LALLEPVPARRRPLPQLAPHLA----RRLLRQ------LPGGTRIRTTLDAGLQRRLERLVRRYVRRLKQNGIHNAAVLV 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 327 TNPQTGEILAMVGSKDYFNLNEDGQVNLTTSLRQPGSSIKPINYALAFEKGL-RPSSTIEDKPISFnlvgqGPWVPKNYD 405
Cdd:COG4953 310 VDNRTGEVLAYVGSADFFDASRQGQVDMVRALRSPGSTLKPFLYGLALDQGLiHPETLLADVPTSF-----GGYRPENFD 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 406 GRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITT-WNEPERYGLSMALGSLEVKMTDLATAYSTFANKGI 484
Cdd:COG4953 385 GTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLlLPPAEHYGLSLILGGAEVTLEELVGLYAALARGGE 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 485 ATPLKSIISVKTRESKDLFlascpmqmiaDPESatalatdqscskkravspltAYLITDVLSDNSARTPAFGFNSVLNik 564
Cdd:COG4953 465 ARPLRLLAGEPASPGRRLL----------SPGA--------------------AWLVRDILSDVPRPDGAFGWRALDS-- 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 565 PAKVAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPMSRVaSGITGASPIWAKIFNQIIEKYPQPKeIAKPDNLISV 644
Cdd:COG4953 513 PPPIAWKTGTSYGFRDAWAVGFTGRYTVGVWVGNPDGTPVPGL-TGAEAAAPLLFDIFDLLPASRWPLP-FPPPAGLLRV 590
|
650 660 670
....*....|....*....|....*....|....
gi 818724561 645 PICTLTGTLTCDGCP-TRNEYFVKGTEPKVSCNP 677
Cdd:COG4953 591 EVCAPSGLLAGPNCPqRVTEWFIPGTSPPTLCPY 624
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
52-684 |
1.32e-142 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 434.16 E-value: 1.32e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 52 TQIVDRHGKLL--YKIYEDENRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFT-KDRLEGGSTITQQ 128
Cdd:TIGR02073 12 TVVLDRHGTLLraLLANDGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTnGRRVSGGSTLTMQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 129 LIKNTLLTNEKTITRKIKELILAFQVENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQ 208
Cdd:TIGR02073 92 LARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 209 APSKYSPyGENPELAYTRQKQVLHQMVKNGFLSVDELDLALTVKLEFSSAKTEINAPHFVMfvkdiltSQLGENivNHGG 288
Cdd:TIGR02073 172 APSARRL-DRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPALPEPLPQLAPHFAL-------KLLRAR--PEIA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 289 LIVTTTLDLELQNLAQKAVTEEVSKLKNFNVSNGAALVTNPQTGEILAMVGSKDYFNLNEDGQVNLTTSLRQPGSSIKPI 368
Cdd:TIGR02073 242 SVIVSTLDADLQRRLEELARRYLSALRPRGISNLAILVVDNRSGAVLAYVGSADFFDDSNSGQVDGVRAPRSPGSTLKPF 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 369 NYALAFEKGL-RPSSTIEDKPISFnlvgqGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGI 447
Cdd:TIGR02073 322 LYALALDDGLlHPDSLLKDVPLRF-----GDYAPENFDKTFHGPVPAREALARSLNIPAVRLLERVGPPRFADFLRQAGL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 448 TTWNEPER-YGLSMALGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTReskdlflascpmqmiadPESatalatdqs 526
Cdd:TIGR02073 397 NLLKPKSDyYGLSLALGGAEITLQDLANLYAMLANQGLSGPLRFLQTDAKR-----------------PER--------- 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 527 cskKRAVSPLTAYLITDVLSDNSARTPAFGfnsvLNIKPAK--VAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPM 604
Cdd:TIGR02073 451 ---ERLLSPGAAWIVLDILKDRPRPDDTLP----LSALPTRlpLAWKTGTSYGFRDAWAAGVSGRYTIGVWVGNFDGKPN 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 605 SRVaSGITGASPIWAKIFNQIIEKYPQpkeiAKPDNLISVPICTLTGTLTCDGCP-TRNEYFVKGTEPKVSCNPQLVKTI 683
Cdd:TIGR02073 524 PGF-FGAAAAAPLLFDILDALQASEAS----TLPRPLKEVPGCLVLGNLPILPCPeQISTWFLPGGSPPTLSEPHKPVVI 598
|
.
gi 818724561 684 L 684
Cdd:TIGR02073 599 L 599
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
60-659 |
1.29e-110 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 350.94 E-value: 1.29e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 60 KLLYKIYED--ENRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDRL-EGGSTITQQLIKNTLLT 136
Cdd:TIGR02071 134 KLIAMLYSPngEQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTvQGGSTLTQQLVKNLFLS 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 137 NEKTITRKIKELILAFQVENIFTKDEIFEMYLNQVGFG---GTA-YGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSK 212
Cdd:TIGR02071 214 NERSLWRKANEAYMALILDARYSKDRILELYLNEVYLGqsgDDAiHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSY 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 213 YSPYgENPELAYTRQKQVLHQMVKNGFLSVDELDLALTVKLEFSSAKTEINA-PHFVMFVKDILTSQLGENIVNHGGLIV 291
Cdd:TIGR02071 294 YNPW-RNPDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLGVQKKGGIISRqPAFLQLVRRELRQKLGDKVKDLSGLRI 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 292 TTTLDLELQNLAQKAVTEEVSKL---KNFNVSNGAALVTNPQTGEILAMVGSKDY----FNLNEDGQvnlttslRQPGSS 364
Cdd:TIGR02071 373 FTTLDPVSQSAAEQAVQETIPALkkkKKLPDLEAAMVVTDRFTGEVRAMVGGSDPqfagFNRALQAR-------RQIGSL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 365 IKPINY--ALAFEKGLRPSSTIEDKPISFNLVGQGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLA 442
Cdd:TIGR02071 446 VKPAVYltALSQPDKYRLNTWIEDQPLSIKLSNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTW 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 443 QSMGittWNEPERYGL-SMALGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFLAscpmqmiaDPESATAL 521
Cdd:TIGR02071 526 NKLG---INKDEIPPVpSMLLGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQS--------DPQAEQAV 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 522 ATDqscskkraVSPLTAYLITDVLSDNSARTpafgfnsvLNIKPAK--VAVKTGTSNDLRDNWTIGYTDTFLVASWVGNN 599
Cdd:TIGR02071 595 PSQ--------AAYLTLYAMQQVVQRGTARS--------LGADFPSlsLAGKTGTTNDNRDSWFAGIDGKEVTIIWLGRD 658
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 818724561 600 NNEPMSrvASGITGASPIWAKIFNQIIekyPQPKEIAKPDNLISVPICTLtGTLTCD-GCP 659
Cdd:TIGR02071 659 DNGPTK--LTGASGALQVYARYLSYQT---PEPLLLVPPEGIDWFGVDPQ-GNGGCKaNCP 713
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
58-235 |
8.47e-86 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 267.47 E-value: 8.47e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 58 HGKLLYKIYEdENRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDRL-EGGSTITQQLIKNTLLT 136
Cdd:pfam00912 1 DGTLLAELGE-ENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 137 NEKTITRKIKELILAFQVENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPY 216
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*....
gi 818724561 217 gENPELAYTRQKQVLHQMV 235
Cdd:pfam00912 160 -RNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
13-686 |
1.37e-78 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 268.54 E-value: 1.37e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 13 LRVSVVLCTLIISSVIF--YNEIIIDLPNPHSLRNFPDKLTTQIVDRHGKLLYKiYEDENRTLIKLNDLPPHIKNAFLTA 90
Cdd:PRK11636 7 LLILAVCCILLGAGSIYglYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQ-YGEKRRIPLTLDQIPPEMVKAFIAT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 91 EDKDFYHHKGFSPVGLVRAVYKNFTKDRL-EGGSTITQQLIKNTLLTNEKTITRKIKELILAFQVENIFTKDEIFEMYLN 169
Cdd:PRK11636 86 EDSRFYEHHGVDPVGIFRAASVALFSGHAsQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 170 QVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSP-YgeNPELAYTRQKQVLHQMVKNGFLSVDELDLA 248
Cdd:PRK11636 166 KIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPlY--SMDRAVARRNVVLSRMLDEGYITQAQYDQA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 249 LTVKLEFSSAKTEI--NAPHFVMFVKDILTSQLGENIVNHgGLIVTTTLDLELQNLAQKAVTEEV--------------- 311
Cdd:PRK11636 244 RSEPIVANYHAPEIafSAPYLSEMVRQEMYNRYGENAYED-GYRVYTTITRKVQQAAQQAVRNNVldydmrhgyrgpanv 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 312 ---------------SKLKNFNV---------------------SNG--------------------------------- 322
Cdd:PRK11636 323 lwkvgesawdnkkitDTLKALPTygpllpavvtsanpqeatamlADGssvalpmegvrwarpyrsdtqqgptprkvtdvv 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 323 ------------------------AALVT-NPQTGEILAMVGSKDyFNLNEDGQVnlTTSLRQPGSSIKPINYALAFEKG 377
Cdd:PRK11636 403 qtgqqiwvrqvddawwlaqvpdvnSALVSiNPQNGAVMALVGGFD-FNQSKFNRA--TQALRQVGSNIKPFLYTAAMDKG 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 378 LRPSSTIEDKPISFNLVGQGP-WVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGITTWN--EPE 454
Cdd:PRK11636 480 LTLASMLNDVPISRWDAGAGSdWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNivHTE 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 455 ryglSMALGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFLA-------SCPMQMI-ADPESATALATD-- 524
Cdd:PRK11636 560 ----SLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAkpkvacpECDIPVIyGDTQKSNVLENDdv 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 525 ----QSCSKKRAVSPLT---------------------------AYLITDVLSDNSARTPAF---GFNSVLNIKPAKVAV 570
Cdd:PRK11636 636 envaTSQEQQNSSVPMPqleqanqalvaqngaqeyaphvintplAFLIKSALNTNIFGEPGWmgtGWRAGRDLKRRDIGG 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 571 KTGTSNDLRDNWTIGYTDTFLVASWVG-NNNNEPMSRV-ASG-----ITG-------ASPIWAKIFNQIIEKYPQpKEIA 636
Cdd:PRK11636 716 KTGTTNSSKDAWFSGYGPGVVTSVWIGfDDHRRDLGRTtASGaikdqISGyeggaksAQPAWDDYMKAALEGVPE-QPLT 794
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 818724561 637 KPDNLISVPICTLTGTLTcDGCPTRNEYFVKGTEPKVSCNPQLVKTILES 686
Cdd:PRK11636 795 PPPGIVTVNIDRSTGKLA-NGGNSREEYFIEGTQPTQQAVHEVGTTIIDN 843
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
69-696 |
6.79e-73 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 252.38 E-value: 6.79e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 69 ENRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGSTITQQLIKNTLLTNEKTITRKIKE 147
Cdd:PRK09506 209 EQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRtVQGGSTLTQQLVKNLFLSNERSLWRKANE 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 148 LILAFQVENIFTKDEIFEMYLNQVGFGGTA----YGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSPYgENPELA 223
Cdd:PRK09506 289 AYMALIMDARYSKDRILELYLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPW-RNPKLA 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 224 YTRQKQVLHQMVKNGFLSVDELDLaLTVKLEFSSAKTEINAPH--FVMFVKDILTSQLGENIVNHGGLIVTTTLDLELQN 301
Cdd:PRK09506 368 LERRNLVLRLLQQQQIIDQELYDM-LSARPLGVQPKGGVISPQpaFMQMVRQELQAKLGDKVKDLSGVKIFTTLDPVSQD 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 302 LAQKAVTEEVSKL-KNFNVSN--GAALVTNPQTGEILAMVGSKD--YFNLNEDGQVNlttslRQPGSSIKPINY--ALAF 374
Cdd:PRK09506 447 AAEKAVEEGIPALkKQRKLSDleTAMVVVDRFSGEVRAMVGGSEpqFAGYNRAMQAR-----RSIGSLAKPATYltALSQ 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 375 EKGLRPSSTIEDKPISFNLVGQGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGIttwnePE 454
Cdd:PRK09506 522 PDKYRLNTWIADAPISLRQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGV-----PK 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 455 RYGL---SMALGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFlascpmqmiadpesatalatdQSCSK-K 530
Cdd:PRK09506 597 DQLNpvpAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLY---------------------QSFPQaE 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 531 RAVSPLTAYLITDVLSDNSARtpafGFNSVLNIKPAK--VAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPMSrvA 608
Cdd:PRK09506 656 RAVPAQAAYLTLYTMQQVVQR----GTGRQLGAKYPNlhLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRDNNQPTK--L 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 609 SGITGAspiwAKIFNQIIE-KYPQPKEIAKPDNLISVPICTlTGTLTCDGCPTRNeYFVKGTEPKVSCNPQLVKTILESR 687
Cdd:PRK09506 730 YGASGA----MTIYQRYLEnQTPTPLNLTPPEDIVDMGVDY-DGNFVCGSGGMRV-LPVWTDDPQSLCQQSEMQQQPSQP 803
|
....*....
gi 818724561 688 KPTTSPTPQ 696
Cdd:PRK09506 804 QQQPQQQPA 812
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
48-625 |
1.43e-63 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 225.73 E-value: 1.43e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 48 DKLTTQIVDRHGKLLYKIYEDEN--RTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGST 124
Cdd:PRK11240 37 VNPARVVVAEDGTPLWRFADADGiwRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRvISGGST 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 125 ITQQLIKntLLT-NEKTITRKIKELILAFQVENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFL 203
Cdd:PRK11240 117 LTMQVAR--LLDpHPRTFGGKIRQLWRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 204 AGLPQAPSKYSPyGENPELAYTRQKQVLHQMVKNGFLSVDELDLALTVKLEFSSAKTEINAPhfvMFVKDILTSqlgeni 283
Cdd:PRK11240 195 AVLPQAPSRLRP-DRWPERAEAARNKVLERMAEQGVWSAEQVKESREEPVWLAPRQMPQLAP---LFARMMLGK------ 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 284 vNHGGLIVTT---TLDLELQNLAQ--KAVTEEVSKLknfnvsngAALVTNPQTGEILAMVGSKDyfnLNED---GQVNLT 355
Cdd:PRK11240 265 -SKSDKIVTTldaGLQRRLEDLALnwKGRLPPRSSL--------AMIVVDHTDMAVRGWVGSVD---LNDDsrfGHVDMV 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 356 TSLRQPGSSIKPINYALAFEKGL-RPSSTIEDKPISFnlvgqGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNG 434
Cdd:PRK11240 333 NAIRSPGSVLKPFVYGLALDDGLiHPASLLQDVPRRT-----GDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYG 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 435 IQNFANLAQSMGITTW----NEPErygLSMALGSLEVKMTDLATAYSTFANKGIATPLKsiisvktreskdlflascpmq 510
Cdd:PRK11240 408 PKRFAAKLRNVGLPLYlpagAEPN---LSLILGGAGARLEDMVAAYSAFARHGKAAKLR--------------------- 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 511 miadpesataLATDQSCSKKRAVSPLTAYLITDVLSDNSARTPAfgfnsvlNIKPAKV--AVKTGTSNDLRDNWTIGYTD 588
Cdd:PRK11240 464 ----------LQPDDPLLERPLMSPGAAWIIRRIMADEAQPLPD-------AALPRVVplAWKTGTSYGYRDAWAIGVNA 526
|
570 580 590
....*....|....*....|....*....|....*....
gi 818724561 589 TFLVASWVGNNNNEPmsrVAS--GITGASPiwakIFNQI 625
Cdd:PRK11240 527 RYVIGIWTGRPDGTP---VVGqfGFASAVP----LLNQV 558
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
60-646 |
5.83e-63 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 223.57 E-value: 5.83e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 60 KLLYKIY--EDENRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGSTITQQLIKNTLLT 136
Cdd:PRK14850 144 KLIAMLYspEGKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHtIQGGSTLTQQLVKNLFLT 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 137 NEKTITRKIKELILAFQVENIFTKDEIFEMYLNQVGFGGTA----YGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSK 212
Cdd:PRK14850 224 NTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYALLVGMVKGASL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 213 YSPYgENPELAYTRQKQVLHQMVKNGFLSVDELDLALTVKLEFSSaKTEINA--PHFVMFVKDILTSQLGENIVNHGGLI 290
Cdd:PRK14850 304 YNPW-TNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNVQS-KGNIISshPAFIQLVCEEFHKKIHYPFKNFSGTK 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 291 VTTTLDLELQNLAQKAVTEEVSKLKN-FNVSN--GAALVTNPQTGEILAMVGSKD-YFNlnedGQVNLTTSLRQPGSSIK 366
Cdd:PRK14850 382 IFTTLDYISQNAAEQAVKIGIPILKRkKRLKDleVAMVIIDRFSGEVRALIGSSKpEFN----GYNRALKARRSIGSLSK 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 367 PINY--ALAFEKGLRPSSTIEDKPISFNLVGQGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQS 444
Cdd:PRK14850 458 PITYltALSQPEKYHLNTWISDTPISIKLDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWIL 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 445 MGITTwNEPERYGlSMALGSLEVKMTDLATAYSTFANKGIATPLKSIISVKTRESKDLFLASCPMQMIADPESATalatd 524
Cdd:PRK14850 538 LGISS-NYITPLP-SISLGAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASY----- 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 525 qscskkravspLTAYLITDVLSDNSARTPAFGFNSVlnikpaKVAVKTGTSNDLRDNWTIGYTDTFLVASWVGNNNNEPM 604
Cdd:PRK14850 611 -----------LTLYAMQQVVKSGTAKSLGTIFKEF------SLAGKTGTTNNLVDSWFVGIDGKQVVITWIGRDNNHTT 673
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 818724561 605 SrvASGITGASPIWAkifNQIIEKYPQPKEIAKPDNLISVPI 646
Cdd:PRK14850 674 K--LYGSSGAMKIYK---RYLQYQNPVPLVLKAPNNINMFYI 710
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
68-250 |
6.70e-34 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 129.54 E-value: 6.70e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 68 DENRTLIKLNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDRLEGGSTITQQLIKNTLLTNEKTITRKIKE 147
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNERSFTRKVKE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 148 LILAFQVENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLN-------IAQASFLAGLPQAPSKY--SPYGE 218
Cdd:PRK13481 122 LFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSttmshitVLQSAILASKVNAPSVYniNDMSE 201
|
170 180 190
....*....|....*....|....*....|..
gi 818724561 219 NPElayTRQKQVLHQMVKNGFLSVDELDLALT 250
Cdd:PRK13481 202 NFT---QRVSTNLEKMKQQNYINETQYQQAMS 230
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
76-234 |
9.81e-32 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 122.96 E-value: 9.81e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 76 LNDLPPHIKNAFLTAEDKDFYHHKGFSPVGLVRAVYKNFTKDR-LEGGSTITQQLIKNTLLTNEKTITRKIKELILAFQV 154
Cdd:TIGR02070 60 YDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKvVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWML 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 155 ENIFTKDEIFEMYLNQVGFGGTAYGIQEASMQYFNIDAKDLNIAQASFLAGLPQAPSKYSpygENPELAYTRQKQ--VLH 232
Cdd:TIGR02070 140 ETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYD---ENRPGPYVRRKAtwILK 216
|
..
gi 818724561 233 QM 234
Cdd:TIGR02070 217 QM 218
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
291-632 |
2.93e-28 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 119.93 E-value: 2.93e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 291 VTTTLDLELQNLAQKAVTEEVsklKNFNVSNGAALVTNPQTGEILAMVgSKDYFNLNE------DGQVNLTTSLRQ-PGS 363
Cdd:COG0768 221 LVLTIDSDLQKIAEEALKKAV---EEYKAKSGAVVVMDPKTGEILAMA-SYPSFDPNLfvggpdEPLRNRAVQGTYePGS 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 364 SIKPINYALAFEKGL-RPSSTIEDkPISFNLvgqGPWVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLA 442
Cdd:COG0768 297 TFKPFTAAAALEEGViTPDTTFDC-PGYYRV---GGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 443 QSMGI-------------------TTWNEPERYglSMALGSlEVKMTDL--ATAYSTFANKGIA-TP--LKSIISVKTRE 498
Cdd:COG0768 373 KKFGLgqktgidlpgeasgllpspKRWYPGETA--TMSIGQ-GLSVTPLqlAQAYAAIANGGVLvKPhlVKEIVDPDGEV 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 499 SKdlflascpmqmiadpesatalatDQSCSKKRAVSPLTAYLITDVLSDNSARTpaFGFNSVLNIKPAKVAVKTGTSnDL 578
Cdd:COG0768 450 VK-----------------------EEPEVLRRVISPETAETVREGMEGVVNEP--GGTARRAAIPGYRVAGKTGTA-QV 503
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 818724561 579 RDNWTIGYTDTFLVASWVG---NNN---------NEPmSRVASGITGASPIWAKIFNQIIEKYPQP 632
Cdd:COG0768 504 VDIGNGGYYKGRHIASFVGfapADNpryavavvvENP-GGGAYGGTVAAPVFREIMEAYLRLLGPP 568
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
322-627 |
6.94e-22 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 96.72 E-value: 6.94e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 322 GAALVTNPQTGEILAMVGSKDYFNLNEDGQVN--LTTSLRQPGSSIKPINYALAFEKG-LRPSSTIEDKPISFnlvgQGP 398
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIGPLRnrAVTSRYEPGSTFKPFTALAALDNGvLKPDETIFDWPGKQ----QGG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 399 WVPKNYDGRFHGTISLRQALGSSYNIPSIMLLSQNGIQNFANLAQSMGI----------TTWNEPERYGLSMALGSLE-- 466
Cdd:pfam00905 77 KSIGDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgiglpgENAGYLTPYWLEGATASFGig 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 467 VKMT--DLATAYSTFANKGIATPLKSIISVKTReskdlflascpmqmiadpesatalaTDQSCSKKRAVSPLTAYLITDV 544
Cdd:pfam00905 157 LTITplQQAQAYAAIANGGKLVPPHLVKSIEDK-------------------------VDPKVLNKLPISKSTAEKVKDM 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 545 LSDNSARTPAFGFNSVLNIkpaKVAVKTGT--SNDLRDNwtiGYTDTFLVASWVG----NNNNEPMSRV--ASGITGASP 616
Cdd:pfam00905 212 LRLVVNDGTGTGTAAVPGY---KVAGKTGTaqVAGPKGG---GYYDGAQIGWFVGyapaDNPKYAFAVLidDPKRYYGGK 285
|
330
....*....|.
gi 818724561 617 IWAKIFNQIIE 627
Cdd:pfam00905 286 VAAPIFKDILE 296
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
261-575 |
2.13e-14 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 76.41 E-value: 2.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 261 EINAPHFVMFVKDILTSQLGENIVnhgglivtTTLDLELQNLAQKAVTEEvsklknfnvsNGAALVTNPQTGEILAMV-- 338
Cdd:TIGR03423 206 EVNARGRVIRTLSRVPPVPGKDLV--------LTIDARLQQAAEKALGGR----------RGAVVVMDPRTGEILAMVst 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 339 ------------GSKDYFNLNEDGQVNL----TTSLRQPGSSIKPINYALAFEKGLR-PSSTIEDkPISFNLvgqGPWVP 401
Cdd:TIGR03423 268 psfdpnlfvdgiSSKDYKALLNDPDRPLlnraIQGVYPPGSTFKPVVALAALEEGVItPETRIYC-PGYFQL---GGRRF 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 402 KNYDGRFHGTISLRQALGSS-----YNIPSIMllsqnGIQNFANLA------QSMGITTWNE-------PE----RYG-- 457
Cdd:TIGR03423 344 RCWKRGGHGRVDLRKAIEEScdvyfYQLALRL-----GIDKIAEYAkrfgfgQKTGIDLPGEksglvpsREwkrkRFGqp 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 458 ------LSMALGSLEVKMT--DLATAYSTFANKGIATP---LKSIIsvktreskdlflascpmqmiaDPESATALATDQS 526
Cdd:TIGR03423 419 wypgdtLNVSIGQGYVLVTplQLAVATAALANGGKLYKphlVKSIE---------------------DPDGGVVRRTEPE 477
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 818724561 527 CSKKRAVSPLTAYLITDVLSD--NSAR-TpafGFNSVLNiKPAKVAVKTGTS 575
Cdd:TIGR03423 478 VLRPLPISPENLDVVREGMRDvvNGPGgT---ARRARLG-LPYKMAGKTGTA 525
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
275-494 |
5.10e-07 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 52.90 E-value: 5.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 275 LTSQLGENIV---NHGGLI--VTTTLDLELQNLA-------QKAVTEEVSKLKNFN-VSNGAALVTNPQTGEILAMVGSK 341
Cdd:PRK15105 199 LTGQPGERIVrkdRYGRVIedISSTDSQAAHNLAlsiderlQALVYRELNNAVAFNkAESGSAVLVDVNTGEVLAMANSP 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 342 DYfNLN------EDGQVNLT-TSLRQPGSSIKPINYALAFEKGL-RPSSTIEDKPISFNlvgqGPWVPknyDGRFHGTIS 413
Cdd:PRK15105 279 SY-NPNnlsgtpKDAMRNRAiTDVFEPGSTVKPMVVMTALQRGVvKENSVLNTVPYRIN----GHEIK---DVARYSELT 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 414 LRQALGSSYNI---------PSIMLL---SQNGIQNFANL---AQSMGI----TTWNEPERYGLSMALGsLEVKMTDLAT 474
Cdd:PRK15105 351 LTGVLQKSSNVgvsklalamPSSALVdtySRFGLGKATNLglvGERSGLypqkQRWSDIERATFSFGYG-LMVTPLQLAR 429
|
250 260
....*....|....*....|
gi 818724561 475 AYSTFANKGIATPLkSIISV 494
Cdd:PRK15105 430 VYATIGSYGIYRPL-SITKV 448
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
291-367 |
1.66e-04 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 44.76 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818724561 291 VTTTLDLELQNLAQKAVTEevsklknfnvSNGAALVTNPQTGEILAMV--------------GSKDYFNLNEDGQVNL-- 354
Cdd:PRK10795 251 IYLTLDLKLQQYIETLLAG----------SRAAVVVTDPRTGGILALVstpsydpnlfvdgiSSKDYSGLLNDPNRPLin 320
|
90
....*....|....*
gi 818724561 355 --TTSLRQPGSSIKP 367
Cdd:PRK10795 321 raTQGVYPPASTVKP 335
|
|
| |
