|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
6-474 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 1038.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 6 VYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALP 85
Cdd:PRK11933 2 VYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEDALP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 86 LGSTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRC 165
Cdd:PRK11933 82 LGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISRC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 166 GISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYS 245
Cdd:PRK11933 162 GVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVYS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 246 TCTLNQEENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVG 325
Cdd:PRK11933 242 TCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKVG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 326 NFPFSPVKDREAGQIRQATAGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIAL 405
Cdd:PRK11933 322 KFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIAL 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 944438637 406 ASPDNMNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKL 474
Cdd:PRK11933 402 ASPDNANAFELTPQEAEEWYMGRDIYPQTAPPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGKL 470
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
41-310 |
3.14e-156 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 443.83 E-value: 3.14e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 41 IRVNTLKISVADFLQLTAPYGWTLtpIPWCEEGFWieRDNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADdnAPQR 120
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVL--EPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPR--EDER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 121 VMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEmFDAILLDAPCSGE 200
Cdd:TIGR00446 75 VLDMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 201 GVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGDLFPG 280
Cdd:TIGR00446 154 GVIRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFG 233
|
250 260 270
....*....|....*....|....*....|.
gi 944438637 281 ANKAL-TEEGFLHVFPQIYDCEGFFVARLRK 310
Cdd:TIGR00446 234 INIGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Ncl1 |
COG3270 |
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and ... |
12-470 |
3.57e-119 |
|
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442501 [Multi-domain] Cd Length: 452 Bit Score: 356.70 E-value: 3.57e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 12 FLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAE 91
Cdd:COG3270 3 PLLELFQLMMLLLLEEEAAFAAALRLLRRSSLRVLLLKAAEDLALRLLAPPPLLPPPPWPEGGGYEEDEELGGPLGLAAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 92 HLSGLFYIQEASSMLPVAALFADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVA 171
Cdd:COG3270 83 ALYYLQEAAAASSALPVAALPGLLLLLAAAAGGAAATAAAAAQGGLLLNLLNIILALELLASSVEVLHANIVVVVNTNTP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 172 LTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQ 251
Cdd:COG3270 163 LAELAGFVFFDALDADADASLLGGGFPREGAAAKEADPLRKASAEIQLEIEAAAAAALLLGGGALLLTTTTEPSEEEEEE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 252 EENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPfsp 331
Cdd:COG3270 243 EELLLLLEELDLALEPAVEEGAGEGGDPEAAAALTELLGLHRFPPHGEGGGGFFAALKKKAGDEPSPKKKKKKKKPK--- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 332 vkdrEAGQIRQATAGVGLNWDENLRLWQRDKELWLFPVGIEALiGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNM 411
Cdd:COG3270 320 ----QAKEVLRAFAEEGLPLPEVGRLWERGGKLYLLPEELPDL-SGLKVLRIGLKLGEIKKKRFEPSHALALALGPEATK 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 944438637 412 NAFELTPQEAEEWYRGRDVYPQAAPvADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVR 470
Cdd:COG3270 395 NVVELDAEEALRYLKGEDIELEDGD-KGWVLVTYDGYPLGWGKYVGGRLKNHYPKGLRR 452
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
119-309 |
1.10e-51 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 173.76 E-value: 1.10e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 119 QRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPE-MFDAILLDAPC 197
Cdd:pfam01189 10 ETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGvLFDRILLDAPC 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 198 SGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDaVEFLPLgDL 277
Cdd:pfam01189 90 SGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHPD-VELVPT-PL 167
|
170 180 190
....*....|....*....|....*....|..
gi 944438637 278 FPGANKALTEEGFLHVFPQIYDCEGFFVARLR 309
Cdd:pfam01189 168 FEPVGLAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
120-245 |
1.02e-03 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 38.57 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 120 RVMDVAAAPGSKTTQIAARmnNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSg 199
Cdd:cd02440 1 RVLDLGCGTGALALALASG--PGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESFDVIISDPPLH- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 944438637 200 egvvrkdpdalknWSPESnqeiaatQRELIDSAFHALRPGGTLVYS 245
Cdd:cd02440 78 -------------HLVED-------LARFLEEARRLLKPGGVLVLT 103
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
6-474 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 1038.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 6 VYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALP 85
Cdd:PRK11933 2 VYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEDALP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 86 LGSTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRC 165
Cdd:PRK11933 82 LGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISRC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 166 GISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYS 245
Cdd:PRK11933 162 GVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVYS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 246 TCTLNQEENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVG 325
Cdd:PRK11933 242 TCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKVG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 326 NFPFSPVKDREAGQIRQATAGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIAL 405
Cdd:PRK11933 322 KFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIAL 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 944438637 406 ASPDNMNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKL 474
Cdd:PRK11933 402 ASPDNANAFELTPQEAEEWYMGRDIYPQTAPPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGKL 470
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
41-310 |
3.14e-156 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 443.83 E-value: 3.14e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 41 IRVNTLKISVADFLQLTAPYGWTLtpIPWCEEGFWieRDNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADdnAPQR 120
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVL--EPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPR--EDER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 121 VMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEmFDAILLDAPCSGE 200
Cdd:TIGR00446 75 VLDMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 201 GVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGDLFPG 280
Cdd:TIGR00446 154 GVIRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFG 233
|
250 260 270
....*....|....*....|....*....|.
gi 944438637 281 ANKAL-TEEGFLHVFPQIYDCEGFFVARLRK 310
Cdd:TIGR00446 234 INIGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Ncl1 |
COG3270 |
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and ... |
12-470 |
3.57e-119 |
|
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442501 [Multi-domain] Cd Length: 452 Bit Score: 356.70 E-value: 3.57e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 12 FLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAE 91
Cdd:COG3270 3 PLLELFQLMMLLLLEEEAAFAAALRLLRRSSLRVLLLKAAEDLALRLLAPPPLLPPPPWPEGGGYEEDEELGGPLGLAAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 92 HLSGLFYIQEASSMLPVAALFADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVA 171
Cdd:COG3270 83 ALYYLQEAAAASSALPVAALPGLLLLLAAAAGGAAATAAAAAQGGLLLNLLNIILALELLASSVEVLHANIVVVVNTNTP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 172 LTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQ 251
Cdd:COG3270 163 LAELAGFVFFDALDADADASLLGGGFPREGAAAKEADPLRKASAEIQLEIEAAAAAALLLGGGALLLTTTTEPSEEEEEE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 252 EENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPfsp 331
Cdd:COG3270 243 EELLLLLEELDLALEPAVEEGAGEGGDPEAAAALTELLGLHRFPPHGEGGGGFFAALKKKAGDEPSPKKKKKKKKPK--- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 332 vkdrEAGQIRQATAGVGLNWDENLRLWQRDKELWLFPVGIEALiGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNM 411
Cdd:COG3270 320 ----QAKEVLRAFAEEGLPLPEVGRLWERGGKLYLLPEELPDL-SGLKVLRIGLKLGEIKKKRFEPSHALALALGPEATK 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 944438637 412 NAFELTPQEAEEWYRGRDVYPQAAPvADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVR 470
Cdd:COG3270 395 NVVELDAEEALRYLKGEDIELEDGD-KGWVLVTYDGYPLGWGKYVGGRLKNHYPKGLRR 452
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
8-311 |
1.01e-96 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 298.46 E-value: 1.01e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 8 FPDAFLTQMREAMPSTlSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIErdneDALPLG 87
Cdd:COG0144 147 HPEWLVERLRAAYGPE-EAEALLAALNEPPPLDLRVNTLKASREELLARLAEEGIEAEPTPLSPDGLRLE----GPGPVT 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 88 STAEHLSGLFYIQEASSMLPVAALfaDDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGI 167
Cdd:COG0144 222 ALPGFREGLFSVQDEASQLVALLL--DPKPGERVLDLCAAPGGKTLHLAELMGNKGRVVAVDISEHRLKRLRENLARLGL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 168 SNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTC 247
Cdd:COG0144 300 SNVEVVVADARELLEWLPGKFDRVLLDAPCSGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLLKPGGRLVYSTC 379
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 944438637 248 TLNQEENEAVCLWLKETYPDAvEFLPLGDLFPGAnkALTEEGFLHVFPQIYDCEGFFVARLRKT 311
Cdd:COG0144 380 SLLPEENEEVVEAFLARHPDF-ELVPLAELLPGL--ALTDGGYLRLLPHRHGTDGFFIARLRKK 440
|
|
| PRK14902 |
PRK14902 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
40-310 |
3.79e-76 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 237857 [Multi-domain] Cd Length: 444 Bit Score: 245.47 E-value: 3.79e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 40 SIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNedalpLGSTAEHLSGLFYIQEASSMLPVAALfaDDNAPQ 119
Cdd:PRK14902 180 SIRVNTLKISVEELIEKLEEEGYEVEESLLSPEALVIEKGN-----IAGTDLFKDGLITIQDESSMLVAPAL--DPKGGD 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 120 RVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSG 199
Cdd:PRK14902 253 TVLDACAAPGGKTTHIAELLKNTGKVVALDIHEHKLKLIEENAKRLGLTNIETKALDARKVHEKFAEKFDKILVDAPCSG 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 200 EGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDaVEFLPLGDLFP 279
Cdd:PRK14902 333 LGVIRRKPDIKYNKTKEDIESLQEIQLEILESVAQYLKKGGILVYSTCTIEKEENEEVIEAFLEEHPE-FELVPLQHEKP 411
|
250 260 270
....*....|....*....|....*....|.
gi 944438637 280 GANKALTEEGFLHVFPQIYDCEGFFVARLRK 310
Cdd:PRK14902 412 DELVYEVKDGYLQILPNDYGTDGFFIAKLRK 442
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
119-309 |
1.10e-51 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 173.76 E-value: 1.10e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 119 QRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPE-MFDAILLDAPC 197
Cdd:pfam01189 10 ETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGvLFDRILLDAPC 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 198 SGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDaVEFLPLgDL 277
Cdd:pfam01189 90 SGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHPD-VELVPT-PL 167
|
170 180 190
....*....|....*....|....*....|..
gi 944438637 278 FPGANKALTEEGFLHVFPQIYDCEGFFVARLR 309
Cdd:pfam01189 168 FEPVGLAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| PRK14901 |
PRK14901 |
16S rRNA methyltransferase B; Provisional |
31-312 |
2.13e-47 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237856 [Multi-domain] Cd Length: 434 Bit Score: 169.34 E-value: 2.13e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 31 AACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEegfwierdneDALPLGSTAEHLS-------GLFYIQEAS 103
Cdd:PRK14901 171 KWFNQPPSLDLRINPLRTSLEEVQAALAEAGITATPIPGLP----------QGLRLTGNPGSIRqlpgyeeGWWTVQDRS 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 104 SMLpVAALFAddnaPQ---RVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVF 180
Cdd:PRK14901 241 AQL-VAPLLD----PQpgeVILDACAAPGGKTTHIAELMGDQGEIWAVDRSASRLKKLQENAQRLGLKSIKILAADSRNL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 181 GAAVPE---MFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAV 257
Cdd:PRK14901 316 LELKPQwrgYFDRILLDAPCSGLGTLHRHPDARWRQTPEKIQELAPLQAELLESLAPLLKPGGTLVYATCTLHPAENEAQ 395
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 944438637 258 CLWLKETYPDAveflplgdlfpganKALTEEgfLHVFPQIYDCEGFFVARLRKTQ 312
Cdd:PRK14901 396 IEQFLARHPDW--------------KLEPPK--QKIWPHRQDGDGFFMAVLRKKS 434
|
|
| Methyltr_RsmF_N |
pfam17125 |
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the ... |
9-104 |
3.16e-36 |
|
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the RsmF methyl transferase. RsmF is a multi-site-specific methyltransferase that is responsible for the synthesis of three modifications on cytidines in 16S ribosomal RNA. The N-terminus is critical for stabilising the catalytic core of the enzyme.
Pssm-ID: 465356 [Multi-domain] Cd Length: 88 Bit Score: 128.75 E-value: 3.16e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 9 PDAFLTQMREAMPStlSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTApygWTLTPIPWCEEGFWIERDNEdalpLGS 88
Cdd:pfam17125 2 PEAFIERMRALLGD--EYEAFLAAYDEPRPVGLRVNTLKISVEEFLKLSP---FELEPVPWCEEGFYLEERPR----PGK 72
|
90
....*....|....*.
gi 944438637 89 TAEHLSGLFYIQEASS 104
Cdd:pfam17125 73 HPYHHAGLYYIQEPSA 88
|
|
| PRK14903 |
PRK14903 |
16S rRNA methyltransferase B; Provisional |
34-311 |
3.56e-35 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 184896 [Multi-domain] Cd Length: 431 Bit Score: 135.77 E-value: 3.56e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 34 QRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEdalPLGSTAEHLSGLFYIQ-EASSMLPvaaLF 112
Cdd:PRK14903 159 QEPLPTMLRVNSLAITREEVIKILAEEGTEAVPGKHSPFSLIVRKLGV---NMNDSRVIKDGLATVQgESSQIVP---LL 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 113 ADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAIL 192
Cdd:PRK14903 233 MELEPGLRVLDTCAAPGGKTTAIAELMKDQGKILAVDISREKIQLVEKHAKRLKLSSIEIKIADAERLTEYVQDTFDRIL 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 193 LDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDaVEFL 272
Cdd:PRK14903 313 VDAPCTSLGTARNHPEVLRRVNKEDFKKLSEIQLRIVSQAWKLLEKGGILLYSTCTVTKEENTEVVKRFVYEQKD-AEVI 391
|
250 260 270
....*....|....*....|....*....|....*....
gi 944438637 273 PLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKT 311
Cdd:PRK14903 392 DIRDKLEEFEVEGIWDGYGFLMLPDETLTPFYVSVLRKM 430
|
|
| PRK10901 |
PRK10901 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
41-310 |
1.59e-34 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 236790 [Multi-domain] Cd Length: 427 Bit Score: 133.78 E-value: 1.59e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 41 IRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERdnedALPLGST---AEhlsGLFYIQEASSMLpvAALFADDNA 117
Cdd:PRK10901 174 LRVNRRHHSRDAYLALLAEAGIEAFPHAVGPDAIRLET----PVPVHQLpgfAE---GWVSVQDAAAQL--AATLLAPQN 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 118 PQRVMDVAAAPGSKTTQIAARMNNEGaILANEFSASRVKVLHANISRCGIsNVALTHFDGRVFGAAVP-EMFDAILLDAP 196
Cdd:PRK10901 245 GERVLDACAAPGGKTAHILELAPQAQ-VVALDIDAQRLERVRENLQRLGL-KATVIVGDARDPAQWWDgQPFDRILLDAP 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 197 CSGEGVVRKDPDaLKnW--SPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEfLPL 274
Cdd:PRK10901 323 CSATGVIRRHPD-IK-WlrRPEDIAALAALQSEILDALWPLLKPGGTLLYATCSILPEENEQQIKAFLARHPDAEL-LDT 399
|
250 260 270
....*....|....*....|....*....|....*..
gi 944438637 275 GDLF-PGankalteegfLHVFPQIYDCEGFFVARLRK 310
Cdd:PRK10901 400 GTPQqPG----------RQLLPGEEDGDGFFYALLIK 426
|
|
| rsmB |
TIGR00563 |
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. ... |
8-310 |
4.69e-34 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. The reading frame was originally interpreted as two reading frames, fmu and fmv. The recombinant protein from E. coli was shown to methylate only C967 of small subunit (16S) ribosomal RNA and to produce only m5C at that position. The seed alignment is built from bacterial sequences only. Eukaryotic homologs include Nop2, a protein required for processing pre-rRNA, that is likely also a rRNA methyltransferase, although the fine specificity may differ. Cutoff scores are set to avoid treating archaeal and eukaroytic homologs automatically as functionally equivalent, although they may have very similar roles. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 273141 [Multi-domain] Cd Length: 426 Bit Score: 132.68 E-value: 4.69e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 8 FPDAFLTQMREAMPStlSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERdnedALPLG 87
Cdd:TIGR00563 137 HPEWLVKRLQKAYPG--QWQSICEANNQRPPMWLRINRTKHSRDEWLALLAEAGMKGFPHDLAPDAVRLET----PAAVH 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 88 STAEHLSGLFYIQEASSMLPVAALfaddnAPQR---VMDVAAAPGSKTTQIAARMNnEGAILANEFSASRVKVLHANISR 164
Cdd:TIGR00563 211 ALPGFEEGWVTVQDASAQWVATWL-----APQNeetILDACAAPGGKTTHILELAP-QAQVVALDIHEHRLKRVYENLKR 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 165 CGISNVALThFDGRVFG---AAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGT 241
Cdd:TIGR00563 285 LGLTIKAET-KDGDGRGpsqWAENEQFDRILLDAPCSATGVIRRHPDIKWLRKPRDIAELAELQSEILDAIWPLLKTGGT 363
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 944438637 242 LVYSTCTLNQEENEAVCLWLKETYPDaveflplgdlFPGANKALTEE---GFLHVFPQIYDCEGFFVARLRK 310
Cdd:TIGR00563 364 LVYATCSVLPEENSEQIKAFLQEHPD----------FPFEKTGTPEQvrdGGLQILPHAEEGDGFFYAKLIK 425
|
|
| PRK14904 |
PRK14904 |
16S rRNA methyltransferase B; Provisional |
30-312 |
3.92e-33 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237858 [Multi-domain] Cd Length: 445 Bit Score: 130.56 E-value: 3.92e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 30 LAACQRPLRRSIRVNTLKISVADFLQ--LTAPYGWTLTPIPwceeGFWIERDNEDALPLGSTaehlsGLFYIQEASSMLP 107
Cdd:PRK14904 172 LSYNNQAPLFGFRINRLKTTPEKFLAapADASVTFEKSGLP----NFFLSKDFSLFEPFLKL-----GLVSVQNPTQALA 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 108 VaaLFADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAavPEM 187
Cdd:PRK14904 243 C--LLLNPQPGSTVLDLCAAPGGKSTFMAELMQNRGQITAVDRYPQKLEKIRSHASALGITIIETIEGDARSFSP--EEQ 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 188 FDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPD 267
Cdd:PRK14904 319 PDAILLDAPCTGTGVLGRRAELRWKLTPEKLAELVGLQAELLDHAASLLKPGGVLVYATCSIEPEENELQIEAFLQRHPE 398
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 944438637 268 AVEFLPLGDLFPGANKALTEEGFLHVFPQiyDCEGF---FVARLRKTQ 312
Cdd:PRK14904 399 FSAEPSPGSLPEPFHEVAHPKGAILTLPG--EHEGFdggFAQRLRKNA 444
|
|
| Methyltranf_PUA |
pfam13636 |
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two ... |
421-470 |
1.90e-11 |
|
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two C-terminal domains found on bacterial methyltransferase RsmF that modifies the 16S ribosomal RNA. It has some structural similarity to the RNA-binding PUA domains suggesting that it is involved in RNA recognition. It lies downstream of the catalytic centre of this methyltransferase, family pfam01189.
Pssm-ID: 433368 [Multi-domain] Cd Length: 50 Bit Score: 58.69 E-value: 1.90e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 944438637 421 AEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVR 470
Cdd:pfam13636 1 ALRYLRGETIELDGDLKAGWVLVTYDGFPLGWGKLLGGRLKNLYPKGLRI 50
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
120-245 |
1.02e-03 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 38.57 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 120 RVMDVAAAPGSKTTQIAARmnNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSg 199
Cdd:cd02440 1 RVLDLGCGTGALALALASG--PGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESFDVIISDPPLH- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 944438637 200 egvvrkdpdalknWSPESnqeiaatQRELIDSAFHALRPGGTLVYS 245
Cdd:cd02440 78 -------------HLVED-------LARFLEEARRLLKPGGVLVLT 103
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
109-245 |
4.05e-03 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 38.36 E-value: 4.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944438637 109 AALFADDNAPQRVMDVAAAPGSKTTQIAARMNneGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMF 188
Cdd:COG0500 18 LALLERLPKGGRVLDLGCGTGRNLLALAARFG--GRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAELDPLPAESF 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 944438637 189 DAILLDapcsgeGVVrkdpdalkNWSPESNqeiaatQRELIDSAFHALRPGGTLVYS 245
Cdd:COG0500 96 DLVVAF------GVL--------HHLPPEE------REALLRELARALKPGGVLLLS 132
|
|
| |
