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Conserved domains on  [gi|1024540699|gb|KZY48937|]
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RNA polymerase subunit sigma [Roseovarius sp. HI0049]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12514 super family cl30921
RNA polymerase sigma factor; Provisional
 7-181 1.19e-80

RNA polymerase sigma factor; Provisional


The actual alignment was detected with superfamily member PRK12514:

Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 237.03  E-value: 1.19e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   7 EIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAI 86
Cdd:PRK12514    5 DIEKLIVRVSLGDRDAFSSLYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSGLSPMTWLITIARNHAI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  87 DRKRrARHSTTGDVLTA-TLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK12514   85 DRLR-ARKAVAVDIDEAhDLADPSPGPEAEVIAGDEGQRIDACLEELEKDRAAAVRRAYLEGLSYKELAERHDVPLNTMR 163

                         170
                  ....*....|....*.
gi 1024540699 166 TWLRRSLLKLRECLSR 181
Cdd:PRK12514  164 TWLRRSLLKLRECLSR 179
 
Name Accession Description Interval E-value
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
 7-181 1.19e-80

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 237.03  E-value: 1.19e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   7 EIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAI 86
Cdd:PRK12514    5 DIEKLIVRVSLGDRDAFSSLYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSGLSPMTWLITIARNHAI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  87 DRKRrARHSTTGDVLTA-TLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK12514   85 DRLR-ARKAVAVDIDEAhDLADPSPGPEAEVIAGDEGQRIDACLEELEKDRAAAVRRAYLEGLSYKELAERHDVPLNTMR 163

                         170
                  ....*....|....*.
gi 1024540699 166 TWLRRSLLKLRECLSR 181
Cdd:PRK12514  164 TWLRRSLLKLRECLSR 179
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
 1-181 1.14e-41

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 138.20  E-value: 1.14e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   1 MSSElleiEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISI 80
Cdd:COG1595     1 MSSD----EELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRG-SFRAWLYRI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  81 ARNAAIDR-KRRARHSTTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNV 159
Cdd:COG1595    76 ARNLAIDHlRKRRRRRELLDELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGI 155

                         170       180
                  ....*....|....*....|..
gi 1024540699 160 PLNTMRTWLRRSLLKLRECLSR 181
Cdd:COG1595   156 SEGTVKSRLSRARKKLREALEE 177
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
 21-179 3.66e-30

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 107.82  E-value: 3.66e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  21 AAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDRKRRARHSTTGDV 100
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEG-SFKAWLFRIARNLILDYLRRKRRLRRELD 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1024540699 101 LTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:TIGR02937  80 LLEELLDSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
 26-93 1.88e-12

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 59.52  E-value: 1.88e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1024540699  26 IYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRAN-GLSPMTWLISIARNAAIDRKRRAR 93
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPErGVSFSTWLYTIIRNAIIDYLRKQR 69
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
 122-176 1.75e-05

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 40.55  E-value: 1.75e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1024540699 122 RSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLR 176
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
 7-181 1.19e-80

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 237.03  E-value: 1.19e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   7 EIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAI 86
Cdd:PRK12514    5 DIEKLIVRVSLGDRDAFSSLYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSGLSPMTWLITIARNHAI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  87 DRKRrARHSTTGDVLTA-TLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK12514   85 DRLR-ARKAVAVDIDEAhDLADPSPGPEAEVIAGDEGQRIDACLEELEKDRAAAVRRAYLEGLSYKELAERHDVPLNTMR 163

                         170
                  ....*....|....*.
gi 1024540699 166 TWLRRSLLKLRECLSR 181
Cdd:PRK12514  164 TWLRRSLLKLRECLSR 179
PRK12534 PRK12534
RNA polymerase sigma factor; Provisional
 7-181 1.90e-42

RNA polymerase sigma factor; Provisional


Pssm-ID: 183576 [Multi-domain]  Cd Length: 187  Bit Score: 140.19  E-value: 1.90e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   7 EIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRY---RANGLspmTWLISIARN 83
Cdd:PRK12534   11 ETGRLLTATAGGDRHAFEALYRQTSPKLFGVCLRMIPQRAEAEEVLQDVFTLIWHKAGQFdpsRARGL---TWLAMIARN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  84 AAIDRKRR---ARHSTTGD---VLTATLADPAPGPEtmaiQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERY 157
Cdd:PRK12534   88 KAIDHLRAnapQRRNVALDdagELRAADASPLERTE----RASTRRRIDHCLAELEPPRSELIRTAFFEGITYEELAART 163

                         170       180
                  ....*....|....*....|....
gi 1024540699 158 NVPLNTMRTWLRRSLLKLRECLSR 181
Cdd:PRK12534  164 DTPIGTVKSWIRRGLAKLKACLER 187
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
 1-181 1.14e-41

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 138.20  E-value: 1.14e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   1 MSSElleiEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISI 80
Cdd:COG1595     1 MSSD----EELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRG-SFRAWLYRI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  81 ARNAAIDR-KRRARHSTTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNV 159
Cdd:COG1595    76 ARNLAIDHlRKRRRRRELLDELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGI 155

                         170       180
                  ....*....|....*....|..
gi 1024540699 160 PLNTMRTWLRRSLLKLRECLSR 181
Cdd:COG1595   156 SEGTVKSRLSRARKKLREALEE 177
PRK09646 PRK09646
ECF RNA polymerase sigma factor SigK;
1-179 3.63e-38

ECF RNA polymerase sigma factor SigK;


Pssm-ID: 182015 [Multi-domain]  Cd Length: 194  Bit Score: 129.40  E-value: 3.63e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   1 MSSELLEIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISI 80
Cdd:PRK09646   10 PPAESPDLDALLRRVARGDQDAFAELYDRTSSRVYGLVRRVLRDPGYSEETTQEVYLEVWRTASRFDPARGSALAWLLTL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  81 ARNAAIDRKRRARHSTTGDVLTATLADPAPGPETM--AIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYN 158
Cdd:PRK09646   90 AHRRAVDRVRSEQAASQREVRYGARNVDPAFDQVAeeVEARLERERVRDCLDALTDTQRESVTLAYYGGLTYREVAERLA 169

                         170       180
                  ....*....|....*....|.
gi 1024540699 159 VPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK09646  170 VPLGTVKTRMRDGLIRLRDCL 190
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
 9-181 1.25e-35

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 122.39  E-value: 1.25e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAID- 87
Cdd:PRK11924    1 GQLMPVDATGDKEAFSELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGKG-SARTWLLTIARNVCYDl 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  88 -RKRRARHSTT-GDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK11924   80 lRRRRREKAVLsDDALEPEFAETAETPEAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVK 159

                         170
                  ....*....|....*.
gi 1024540699 166 TWLRRSLLKLRECLSR 181
Cdd:PRK11924  160 SRLRRARQLLRECLEA 175
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
 21-179 3.66e-30

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 107.82  E-value: 3.66e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  21 AAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDRKRRARHSTTGDV 100
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEG-SFKAWLFRIARNLILDYLRRKRRLRRELD 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1024540699 101 LTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:TIGR02937  80 LLEELLDSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
PRK12537 PRK12537
RNA polymerase sigma factor; Provisional
 16-179 4.59e-29

RNA polymerase sigma factor; Provisional


Pssm-ID: 171568 [Multi-domain]  Cd Length: 182  Bit Score: 105.63  E-value: 4.59e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  16 ALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAIDRKR-RARH 94
Cdd:PRK12537   18 ARGDRRALQALYQQESARLLGVARRIVRDRALAEDIVHDAFIKIWTGAASFDPARGSARGWIYSVTRHLALNVLRdTRRE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  95 STTGDVLTATLADPAPGPETMAIQSSErSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLK 174
Cdd:PRK12537   98 VVLDDDAEETAQTLHEIIDDFDLWANS-GKIHRCLEQLEPARRNCILHAYVDGCSHAEIAQRLGAPLGTVKAWIKRSLKA 176


                  ....*
gi 1024540699 175 LRECL 179
Cdd:PRK12537  177 LRECM 181
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
 9-181 1.04e-26

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 99.73  E-value: 1.04e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAIDR 88
Cdd:PRK05602    8 EELLARVAAGDPAAFRVLVARKLPRLLALATRMLGDPAEAEDVAQETFLRIWKQAPSWRPGEARFDTWLHRVVLNLCYDR 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  89 KRRARHSTTGDvlTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWL 168
Cdd:PRK05602   88 LRRRREVPVED--APDVPDPAPGPDAGLEARQRARRVEQALAALPERQREAIVLQYYQGLSNIEAAAVMDISVDALESLL 165

                         170
                  ....*....|...
gi 1024540699 169 RRSLLKLRECLSR 181
Cdd:PRK05602  166 ARGRRALRAQLAD 178
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
 1-179 1.22e-23

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 91.90  E-value: 1.22e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   1 MSSELLEIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISI 80
Cdd:PRK13919    3 LPLESLSDEALLALVARGEEEALRALFRRYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEFDPRRGSARAWLLAL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  81 ARNAAID--RKRRARHSTTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYN 158
Cdd:PRK13919   83 AHHAAVDhvRRRAARPQPLEPDEREPEAFDLPGPGLDEEGHLDRTRLGRALKALSPEERRVIEVLYYQGYTHREAAQLLG 162

                         170       180
                  ....*....|....*....|.
gi 1024540699 159 VPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK13919  163 LPLGTLKTRARRALSRLKEVL 183
PRK12515 PRK12515
RNA polymerase sigma factor; Provisional
 9-181 3.73e-23

RNA polymerase sigma factor; Provisional


Pssm-ID: 183567 [Multi-domain]  Cd Length: 189  Bit Score: 90.56  E-value: 3.73e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDR 88
Cdd:PRK12515   10 EMLLARIAQGDRTAMQTLYGRHHVRVYRFGLRLVRDEQTAEDLVSEVFLDVWRQAGQFEGRS-QVSTWLLSIARFKALSA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  89 KRRARHSTTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWL 168
Cdd:PRK12515   89 LRRRKHEEIDDEAAAAIEDGADTPEVALQKSDTSAALRACLAKLSPAHREIIDLVYYHEKSVEEVGEIVGIPESTVKTRM 168

                         170
                  ....*....|...
gi 1024540699 169 RRSLLKLRECLSR 181
Cdd:PRK12515  169 FYARKKLAELLKA 181
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
 9-179 1.48e-22

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 89.35  E-value: 1.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDR 88
Cdd:PRK12519   17 AELFSALKAGQSAALGVLYDRHAGLVYGLALKILGNSQEAEDLTQEIFLSLWRKSSYDPKRG-SLSSYLLTLTRSRAIDR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  89 KR-RARHSTTGDVLTATLADPAPGPETMAIQS-SERS-RLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK12519   96 LRsRRSRQRLLERWQQELLGEASEDTPLEQASlAERSqRVQTALAQLPESQRQVLELAYYEGLSQSEIAKRLGIPLGTVK 175

                         170
                  ....*....|....
gi 1024540699 166 TWLRRSLLKLRECL 179
Cdd:PRK12519  176 ARARQGLLKLRELL 189
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
 1-180 1.70e-22

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 88.98  E-value: 1.70e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   1 MSSELLEIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISI 80
Cdd:PRK12513    6 MSTAAASDEALMLRYRAGDAAAFEALYARHRTGLYRFLLRLARDRALAEDIFQETWLRVIRARAQYQPRA-RFRTWLYQI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  81 ARNAAIDRKRRARH----STTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGEL--DQQHADAVRrayLEGD-TYAEL 153
Cdd:PRK12513   85 ARNLLIDHWRRHGArqapSLDADEQLHALADDGAAPEQQLSLFRDRRRLQAALETLpdEQREVFLLR---EHGDlELEEI 161

                         170       180
                  ....*....|....*....|....*..
gi 1024540699 154 AERYNVPLNTMRTWLRRSLLKLRECLS 180
Cdd:PRK12513  162 AELTGVPEETVKSRLRYALQKLRELLA 188
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
 12-177 6.46e-21

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 84.47  E-value: 6.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  12 IARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRAnGLSPMTWLISIARNAAIDRKRR 91
Cdd:PRK09652    1 VERVQRGDRAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRG-GAAFYTWLYRIARNTAINYLRK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  92 A-RHSTTGDVLT--------ATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLN 162
Cdd:PRK09652   80 QgRRPPASDVDAeeaedfdlADALRDISTPENELLSAELEQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIG 159

                         170
                  ....*....|....*
gi 1024540699 163 TMRTWLRRSLLKLRE 177
Cdd:PRK09652  160 TVRSRIFRAREALRA 174
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
 9-155 2.34e-19

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 81.09  E-value: 2.34e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAIDR 88
Cdd:PRK12524   14 EALLVLYANGDPAAARALTLRLAPRALAVATRVLGDRAEAEDVTQEAMLRLWRIAPDWRQGEARVSTWLYRVVCNLCTDR 93

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1024540699  89 KRRARHSTTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAE 155
Cdd:PRK12524   94 LRRRRRASVDLDDAPEPADAAPGAEEALIEGDRMRALDAALAALPERQRQAVVLRHIEGLSNPEIAE 160
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
 23-177 9.14e-18

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 76.14  E-value: 9.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  23 FRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANglsPMTWLISIARNAAID--RKRRARHSTTGDV 100
Cdd:PRK09639    5 FEDLFEQYYPDVVQQIFYIVKDRTQAEDLAQEVFLRLYRSDFKGIEN---EKGWLIKSARNVAYNylRSEKRRRARILGE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 101 LTATLADPAPGPETMAIQSSERSRLDGCFGELDQQhadavRRAYL----EGDTYAELAERYNVPLNTMRTWLRRSLLKLR 176
Cdd:PRK09639   82 FQWQEVDNEPSPEEIWIRKEEITKVQEVLAKMTER-----DRTVLllrfSGYSYKEIAEALGIKESSVGTTLARAKKKFR 156


                  .
gi 1024540699 177 E 177
Cdd:PRK09639  157 K 157
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
 9-181 1.22e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 77.31  E-value: 1.22e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDR 88
Cdd:PRK11922   18 RELVARVLAGDEAAFEALMRRHNRRLYRTARAILRNDAEAEDVVQEAYLRAFRALGTFRGDA-SLSTWLSRIVLNEALGR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  89 KRRARH----------STTGDVLTATLADPAPGPETMAIQSSERsrldgcfgELDQQHADAVRRAY--------LEGDTY 150
Cdd:PRK11922   97 LRRRRRlvnlaemvmaSTIAGGERTPLADPAEDPERAAARREIR--------ALLERAIDALPDAFravfvlrvVEELSV 168

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1024540699 151 AELAERYNVPLNTMRTWLRRSLLKLRECLSR 181
Cdd:PRK11922  169 EETAQALGLPEETVKTRLHRARRLLRESLAR 199
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
 7-181 4.36e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 75.66  E-value: 4.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   7 EIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAI 86
Cdd:PRK12538   49 EDEELLDRLATDDEAAFRLLVERHIDRAYAIALRIVGNRADAEDVVQDTMLKVWTHRGRWQHGRAKFSTWLYRVVSNRCI 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  87 DRKRRARHSTTGDVltATLADPAPGPETMaIQSSERSR-LDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK12538  129 DLRRKPRTENVDAV--PEVADGKPDAVSV-IERNELSDlLEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMDTTVAAVE 205

                         170
                  ....*....|....*.
gi 1024540699 166 TWLRRSLLKLRECLSR 181
Cdd:PRK12538  206 SLLKRGRQQLRDLLRR 221
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
15-176 5.17e-16

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 71.65  E-value: 5.17e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  15 MALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAID--RKRRA 92
Cdd:PRK09645    3 MATAEAALMRALYDEHAAPLWRYALRLTGDRARAEDVVQETLLRAWQHPEVLADTGRSARAWLFTVARNLVIDerRSARA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  93 RHSTTGDvltATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSL 172
Cdd:PRK09645   83 RPVEGGD---DVLGVPEQSAPDEVDRALDRLLVADALAQLSPEHRAVLVRSYYRGWSTAQIAADLGIPEGTVKSRLHYAL 159


                  ....
gi 1024540699 173 LKLR 176
Cdd:PRK09645  160 RALR 163
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
 22-179 1.09e-15

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 70.28  E-value: 1.09e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  22 AFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRyRANGLSPMTWLISIARNAAID-------RKRRARH 94
Cdd:TIGR02985   2 AFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRET-LEISESIKAYLFTIVKNRCLNylrhkqvEEKYQEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  95 STTGDVLTATLADPapgPETMAIQSSERsRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLK 174
Cdd:TIGR02985  81 LAEIEERELSEADP---EEELEAKELEE-IIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITKALKF 156


                  ....*
gi 1024540699 175 LRECL 179
Cdd:TIGR02985 157 LRKEL 161
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
 8-181 2.54e-15

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 70.11  E-value: 2.54e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   8 IEDLIARMALR----DRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANgLSPMTWLISIARN 83
Cdd:PRK09641    1 MDLLIKRLIKQvkkgDQNAFAELVDLYKDKIYQLCYRMLGNRHEAEDAAQEAFIRAYVNIDSYDIN-RKFSTWLYRIATN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  84 AAIDRKRRARHS---------TTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELA 154
Cdd:PRK09641   80 LTIDRLRKRKPDyyldaevagTEGLTMYSQLAADDALPEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEIS 159

                         170       180
                  ....*....|....*....|....*..
gi 1024540699 155 ERYNVPLNTMRTWLRRSllklRECLSR 181
Cdd:PRK09641  160 EILDLPVGTVKTRIHRG----REALRK 182
Sig-70_gvs1 TIGR02989
RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma ...
 22-178 1.80e-14

RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).


Pssm-ID: 274379 [Multi-domain]  Cd Length: 159  Bit Score: 67.35  E-value: 1.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  22 AFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRAnGLSPMTWLISIARNAAID--RKRRARHSTTGD 99
Cdd:TIGR02989   2 AFVRLLTRHERALRAFVRSLVADRDDVDDVLQETFVVAWRKFDQFDP-GTNFVAWARGIARNKVLNyrRKLGRDRLVFDD 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1024540699 100 VLTATLADPAPgPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLREC 178
Cdd:TIGR02989  81 DLLEALAAEAE-PTEAERLSDDRQALEGCLEKLPERQRELLDLRYQRGQKATALAEQTGRTVNAVYKALQRIRVSLREC 158
PRK06811 PRK06811
RNA polymerase factor sigma-70; Validated
 9-93 6.11e-13

RNA polymerase factor sigma-70; Validated


Pssm-ID: 180707 [Multi-domain]  Cd Length: 189  Bit Score: 63.81  E-value: 6.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDV---LQDVYVKVWNNADRYRANGLSPMTWLISIARNAA 85
Cdd:PRK06811    6 DNFIKELKKKNEKALEFIVDTYGNLVKKIVHKVLGTVNYSQLIeecVNDIFLSIWNNIDKFDEEKGSFKKWIAAISKYKA 85


                  ....*...
gi 1024540699  86 IDRKRRAR 93
Cdd:PRK06811   86 IDYKRKLT 93
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
 26-93 1.88e-12

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 59.52  E-value: 1.88e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1024540699  26 IYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRAN-GLSPMTWLISIARNAAIDRKRRAR 93
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPErGVSFSTWLYTIIRNAIIDYLRKQR 69
PRK09638 PRK09638
RNA polymerase sigma factor SigY; Reviewed
 6-181 3.86e-12

RNA polymerase sigma factor SigY; Reviewed


Pssm-ID: 182010 [Multi-domain]  Cd Length: 176  Bit Score: 61.19  E-value: 3.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   6 LEIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPmTWLISIARNAA 85
Cdd:PRK09638    3 MDEKELIQKAKKGDDAALTTLFQQHYSFLYKYLLKLTLDPDLAEDLVQETMLKAIENLSSFQGRSKFS-TWLISIASRLY 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  86 IDRKRRARHSTTGDVLTATLADPAPGPEtMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK09638   82 KDHLRKQKREKLRLQRAKEETLRKEKWE-AAIKGAEWSEMLDALSKLDPEFRAPVILKHYYGYTYEEIAKMLNIPEGTVK 160

                         170
                  ....*....|....*.
gi 1024540699 166 TWLRRSLLKLRECLSR 181
Cdd:PRK09638  161 SRVHHGIKQLRKEWGQ 176
PRK12526 PRK12526
RNA polymerase sigma factor; Provisional
 18-177 7.20e-12

RNA polymerase sigma factor; Provisional


Pssm-ID: 237127 [Multi-domain]  Cd Length: 206  Bit Score: 61.36  E-value: 7.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  18 RDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAIDRKRRAR---H 94
Cdd:PRK12526   35 RDKQAFTHLFQFFAPKIKRFGIKQLGNEAQANELVQETMSNVWRKAHLYNGDKGAATTWVYTVMRNAAFDMLRKIKakkE 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  95 STTGD---VLTATLADPAPGPETMAIQSSERSRLDgCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRS 171
Cdd:PRK12526  115 QNLGDdiwPIEQALAESQSESEEFSDHLMDKQILS-YIEKLPEAQQTVVKGVYFQELSQEQLAQQLNVPLGTVKSRLRLA 193


                  ....*.
gi 1024540699 172 LLKLRE 177
Cdd:PRK12526  194 LAKLKV 199
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
 42-179 1.87e-11

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 59.76  E-value: 1.87e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  42 LDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAID--RKRRARHSTTGDVLTATLADPAPGPETMAIQS 119
Cdd:PRK09415   37 VKNKEVAEDLTQEIFVKCYKSLHTYKGKS-SLKTWLYRIAINHCKDylKSWHNKKVIVTEDIFTYMESQKESVEEEVIQN 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 120 SERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK09415  116 AEDERLASAVMSLPIKYREVIYLFYYEELSIKEIAEVTGVNENTVKTRLKKAKELLKKGL 175
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
 25-179 3.69e-11

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 58.84  E-value: 3.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  25 NIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDRKR-RARHSTTGDVLTA 103
Cdd:PRK09637    5 SIWSEYKAQLKAFLHSRVSNEADVDDLLQEVLIKTHSNLHSLKDGS-SIKSWLYQIANNTIIDFYRkKNRSEELPDDLLF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 104 TLADPapgpetmaiQSSERSRLDGCF----GELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK09637   84 EDEER---------EENAKKELAPCLrpfiDALPEKYAEALRLTELEGLSQKEIAEKLGLSLSGAKSRVQRGRVKLKELL 154
PRK12531 PRK12531
RNA polymerase sigma factor; Provisional
 7-176 1.15e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 105726 [Multi-domain]  Cd Length: 194  Bit Score: 57.63  E-value: 1.15e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   7 EIEDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTWLISIARNAAI 86
Cdd:PRK12531   13 EWLECMEKVKSRDKQAFALVFSYYAPKLKQFAMKHVGNEQVAMEMVQETMSTVWQKAHLFDGQKSALSTWIYTIIRNLCF 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  87 D--RKRRAR--HSTTGDVLTATLADP----APGPETMAIQSSERSRLDgcfgELDQQHADAVRRAYLEGDTYAELAERYN 158
Cdd:PRK12531   93 DllRKQKGKdlHIHADDIWPSDYYPPdlvdHYSPEQDMLKEQVMKFLD----RLPKAQRDVLQAVYLEELPHQQVAEMFD 168

                         170
                  ....*....|....*...
gi 1024540699 159 VPLNTMRTWLRRSLLKLR 176
Cdd:PRK12531  169 IPLGTVKSRLRLAVEKLR 186
PRK09643 PRK09643
RNA polymerase sigma factor SigM; Reviewed
 10-179 1.86e-10

RNA polymerase sigma factor SigM; Reviewed


Pssm-ID: 236604 [Multi-domain]  Cd Length: 192  Bit Score: 57.03  E-value: 1.86e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  10 DLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDRK 89
Cdd:PRK09643   16 ELLAAHVAGDRYAFGELFRRHHRRLWAVARRTSGTREDAADALQDAMLSAHRAAGSFRGDA-AVSSWLHRIVVNACLDRL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  90 RRA---RHSTTGDVLTATLADPAPgpetmAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRT 166
Cdd:PRK09643   95 RRAkarPTVPLDDVYPVAQLERDP-----TARVETALAVQRALMRLPVEQRAALVAVDMQGYSVADAARMLGVAEGTVKS 169

                         170
                  ....*....|...
gi 1024540699 167 WLRRSLLKLRECL 179
Cdd:PRK09643  170 RCARGRARLAELL 182
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
 11-179 9.21e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 55.11  E-value: 9.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  11 LIARMALRDRAAFRNIYSRTSAKLFGViLRVLDDRAEAEDVLQDVYVKVWNNADRYRaNGLSPMTWLISIARNAAID-RK 89
Cdd:PRK12518    1 LILRCQRGDRQSFRQLYRRYQQKVRST-LYQLCGRELLDDLVQEVFLRVWKGLPKLR-NPAYFSTWLYRITWNVATDaRR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  90 RRARHSTTGDVLTATLADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLR 169
Cdd:PRK12518   79 QFAQRPSRIQDDSLNDQPSRPSDTPDLMQLHYQDLVQQGLQTLSLEHRAVLVLHDLEDLPQKEIAEILNIPVGTVKSRLF 158

                         170
                  ....*....|
gi 1024540699 170 RSLLKLRECL 179
Cdd:PRK12518  159 YARRQLRKFL 168
PRK09642 PRK09642
RNA polymerase sigma factor;
34-171 3.27e-09

RNA polymerase sigma factor;


Pssm-ID: 170031 [Multi-domain]  Cd Length: 160  Bit Score: 53.18  E-value: 3.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  34 LFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSpmTWLISIARNAAIDRKR-RARHSTTGDVLTATLAD--PAP 110
Cdd:PRK09642    8 IFQVIFSILRHEEDAKDVTQEVFVKIHASLPNYQFRGLK--TWMARIATNHAIDYKRkKARENEELSLCKETEENikSSH 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1024540699 111 GPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRS 171
Cdd:PRK09642   86 NIEDLLLTKEQKLLIAQKLRELPENYRDVVLAHYLEEKSYQEIALQEKIEVKTVEMKLYRA 146
PRK12541 PRK12541
RNA polymerase sigma factor; Provisional
 17-170 1.80e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 183580 [Multi-domain]  Cd Length: 161  Bit Score: 51.09  E-value: 1.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  17 LRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPmtWLISIARNAAIDRKRRARHST 96
Cdd:PRK12541    1 MKRKQSLEEIYSEHMQDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIRP--WLFTIAYNAFIDWYRKEKKYK 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1024540699  97 TGDVLTATLADPAPGPETMAIQSSERSRLDGCFG-ELDQQHADAVRRAYleGDTYAELAERYNVPLNTMRTWLRR 170
Cdd:PRK12541   79 TTTIEEFHLPNVPSTEHEYFIKHEIASWLDSLSSlPLERRNVLLLRDYY--GFSYKEIAEMTGLSLAKVKIELHR 151
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
 26-181 1.99e-08

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 51.03  E-value: 1.99e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  26 IYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPmtWLISIARNAAID--RKRRARHSTTGDVLTA 103
Cdd:PRK09644    6 IYKMYINDVYRYLFSLTKSHHAAEDLLQETFYRAYIYLEDYDNQKVKP--WLFKVAYHTFIDfvRKEKKVSFVGTDEIEA 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1024540699 104 TLADpapGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECLSR 181
Cdd:PRK09644   84 IQAE---STEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRLKALLKE 158
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
10-114 3.55e-08

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 51.86  E-value: 3.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  10 DLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAID-- 87
Cdd:PRK08241    8 ALLARAAAGDRDAFAALVEPHRRELLAHCYRMLGSVHDAEDAVQETLLRAWRGYDRFEGRS-SLRTWLYRIATNVCLDal 86

                          90       100
                  ....*....|....*....|....*....
gi 1024540699  88 --RKRRARHSTTGDVLTATLADPAPGPET 114
Cdd:PRK08241   87 egRARRPLPTDLGAPAADPVDELVERPEV 115
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
 19-177 3.48e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 47.81  E-value: 3.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  19 DRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIA-------------RNAA 85
Cdd:PRK12543    5 DQEAFSEIYDVTIQEVYKTVHFLVEDKQDVDDVVNEIYIQLWESLRKYDSNR-PFRFWLIGLVikqihswrrkrwrRFRI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  86 IDRKRRARHSTTGDVLTATLADpapGPETMAIQSSErsrldgcfgELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMR 165
Cdd:PRK12543   84 FEKAEEQRKPVSIDFSEDVLSK---ESNQELIELIH---------KLPYKLRQVIILRYLHDYSQEEIAQLLQIPIGTVK 151

                         170
                  ....*....|..
gi 1024540699 166 TWLRRSLLKLRE 177
Cdd:PRK12543  152 SRIHAALKKLRQ 163
PRK12511 PRK12511
RNA polymerase sigma factor; Provisional
 44-177 4.23e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 237123 [Multi-domain]  Cd Length: 182  Bit Score: 47.86  E-value: 4.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  44 DRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDRKRRARHSTTGDVLTATLADPA-PGPETMAIQSSER 122
Cdd:PRK12511   27 DSAEAEDLVHDALVRALERRASFRSGG-NLRTWLMSILHNAFIDELRRRRVEARRADELAVLADASlPAAQEHAVRLAQI 105

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1024540699 123 SRldgCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRE 177
Cdd:PRK12511  106 RD---AFFDLPEEQRAALHLVAIEGLSYQEAAAVLGIPIGTLMSRIGRARAALRA 157
algU PRK11923
RNA polymerase sigma factor AlgU; Provisional
 9-171 5.38e-07

RNA polymerase sigma factor AlgU; Provisional


Pssm-ID: 171347 [Multi-domain]  Cd Length: 193  Bit Score: 47.49  E-value: 5.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   9 EDLIARMALRDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDR 88
Cdd:PRK11923    8 QQLVERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDTAEAQDVAQEAFIKAYRALGNFRGDS-AFYTWLYRIAINTAKNH 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  89 -KRRARHSTTGDVlTATLADPAPGPETMA-IQSSERS----RLDGCFGELDQQHADAVRRAY----LEGDTYAELAERYN 158
Cdd:PRK11923   87 lVSRGRRPPDSDV-SSEDAEFYDGDHALKdIESPERAllrdEIEGTVHRTIQQLPEDLRTALtlreFDGLSYEDIASVMQ 165

                         170
                  ....*....|...
gi 1024540699 159 VPLNTMRTWLRRS 171
Cdd:PRK11923  166 CPVGTVRSRIFRA 178
PRK07037 PRK07037
extracytoplasmic-function sigma-70 factor; Validated
 32-179 6.64e-07

extracytoplasmic-function sigma-70 factor; Validated


Pssm-ID: 180803 [Multi-domain]  Cd Length: 163  Bit Score: 46.99  E-value: 6.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  32 AKLFGVILRVLDDRAEAEDVLQDVYVKVWN--NADRYRAnglsPMTWLISIARNAAIDRKRRA----RHSTTGDVlTATL 105
Cdd:PRK07037    9 SMLVKIAARIVGCRSRAEDVVQDAFVKLVEapNQDAVKQ----PVAYLFRIVRNLAIDHYRRQalenKYHGDEED-GLDV 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1024540699 106 ADPAPGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK07037   84 PSPEASPEAALINRDTLRHVADALSELPARTRYAFEMYRLHGETQKDIARELGVSPTLVNFMIRDALVHCRKCL 157
PRK12546 PRK12546
RNA polymerase sigma factor; Provisional
 44-179 2.42e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 139055 [Multi-domain]  Cd Length: 188  Bit Score: 45.60  E-value: 2.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  44 DRAEAEDVLQDVYVKVWNNADRYRAnGLSPMTWLISIARNA--AIDRKRRARHSTTGDVLTATLADPAPGPETMAIQSSE 121
Cdd:PRK12546   30 NVAVADDLVQDTIVKAWTNFDKFQE-GTNLRAWLFTILRNTfySDRRKHKREVPDPEGVHAASLAVKPAHDGRLAMSDFR 108

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1024540699 122 RSrldgcFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK12546  109 AA-----FAQLPDEQREALILVGASGFSYEEAAEMCGVAVGTVKSRANRARARLAELL 161
PRK09640 PRK09640
RNA polymerase sigma factor SigX; Reviewed
 6-180 3.00e-06

RNA polymerase sigma factor SigX; Reviewed


Pssm-ID: 236603 [Multi-domain]  Cd Length: 188  Bit Score: 45.31  E-value: 3.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   6 LEIEDLIARMALR---DRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANgLSPMTWLISIAR 82
Cdd:PRK09640    8 LNDEELVARVHVElfhVTRAYEELMRRYQRTLFNVCARYLGNDRDADDVCQEVMLKVLYGLKNFEGK-SKFKTWLYSITY 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  83 NAAIDRKRRARHSTTgdVLTATLADPAPGP-ETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPL 161
Cdd:PRK09640   87 NECITQYRKERRKRR--LMDALSLDPLEEAsEEKAPKPEERGGLDRWLVHVNPIDREILVLRFVAELEFQEIADIMHMGL 164

                         170
                  ....*....|....*....
gi 1024540699 162 NTMRTWLRRSLLKLRECLS 180
Cdd:PRK09640  165 SATKMRYKRALDKLREKFA 183
PRK12544 PRK12544
RNA polymerase factor sigma-70;
42-180 1.34e-05

RNA polymerase factor sigma-70;


Pssm-ID: 183583 [Multi-domain]  Cd Length: 206  Bit Score: 43.64  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  42 LDDRAEAEDVLQDVYVKVWNNADRYrANGLSPMTWLISIARNAAIDRKR-RARHSTTGDVLTATLA-------------- 106
Cdd:PRK12544   39 LSDLHLAEDAVQEALIGALKNADSF-AGRAAFKTWVFAILKNKIIDLLRqKKRHVSASSLLRDEEEeedfeelfdesghw 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 107 --DPAP----GPETMAIQSSERSRLDGCFGELDQQHADA-VRRAYLEGDTyAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK12544  118 qkDERPqawgNPEESLEQEQFWRIFEACLDGLPAKYARVfMMREFIELET-NEICHAVDLSVSNLNVLLYRARLRLRECL 196


                  .
gi 1024540699 180 S 180
Cdd:PRK12544  197 E 197
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
 122-176 1.75e-05

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 40.55  E-value: 1.75e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1024540699 122 RSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLR 176
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
 33-94 2.17e-05

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 43.37  E-value: 2.17e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1024540699  33 KLFGVILRVLDDRAEAEDVLQDVYVKvWNNADryRANGLSPMTWLISIARNAAIDRKRRARH 94
Cdd:PRK09636   16 HLLSVAYRMLGSVADAEDIVQEAWLR-WNNAD--RAQIRDPRAWLTRVVTRLCLDRLRSARH 74
PRK12545 PRK12545
RNA polymerase factor sigma-70;
42-180 4.57e-05

RNA polymerase factor sigma-70;


Pssm-ID: 183584 [Multi-domain]  Cd Length: 201  Bit Score: 42.25  E-value: 4.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  42 LDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDRKRRARHSTTGDVLTATL---------------- 105
Cdd:PRK12545   29 LRDADAAEDAVQEALAAAWSQAGRFAGQS-AHKTWVFGILRNKLIDTLRARQRTVNLSALDAELdgealldrelfkdngh 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 106 ------ADPAPGPETMAIQSSERSRLDGCFGELDQQHADA-VRRAYLEGDTYAELAErYNVPLNTMRTWLRRSLLKLREC 178
Cdd:PRK12545  108 waahakPRPWPKPETILQQQQFWTLFETCLDHLPEQIGRVfMMREFLDFEIDDICTE-LTLTANHCSVLLYRARTRLRTC 186


                  ..
gi 1024540699 179 LS 180
Cdd:PRK12545  187 LS 188
PRK12547 PRK12547
RNA polymerase sigma factor; Provisional
 31-180 6.17e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 139056 [Multi-domain]  Cd Length: 164  Bit Score: 41.40  E-value: 6.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  31 SAKLFGVILRVLDDRAEaeDVLQDVYVKVWNNADRYRAnGLSPMTWLISIARNAAID--RKRRARHSTTGDVLTATLADP 108
Cdd:PRK12547   18 ALRAFAVSLSSKHDKAE--DLVQDTLMKAWAKQDSFEM-GTNLKAWLFTILRNEFYSqmRKRGREVQDSDGVFTARVAVH 94

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1024540699 109 APGPETMAIQSSERSrldgcFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECLS 180
Cdd:PRK12547   95 PAQYGSLDLQDFKKA-----LNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELLK 161
PRK09651 PRK09651
RNA polymerase sigma factor FecI; Provisional
 40-171 8.25e-05

RNA polymerase sigma factor FecI; Provisional


Pssm-ID: 182018 [Multi-domain]  Cd Length: 172  Bit Score: 41.33  E-value: 8.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  40 RVLDDRAEAEDVLQDVYVKVWNNadryraNGLS----PMTWLISIARNAAIDRKRR-ARHSTTGDVLTATLADPAPGPET 114
Cdd:PRK09651   29 RKLQSAFDADDIAQDTFLRVMVS------ETLStirdPRSFLCTIAKRVMVDLFRRnALEKAYLEMLALMPEGGAPSPEE 102

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1024540699 115 MAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRS 171
Cdd:PRK09651  103 RESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSVSSVKKYVAKA 159
PRK12536 PRK12536
RNA polymerase sigma factor; Provisional
 19-101 8.37e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237131 [Multi-domain]  Cd Length: 181  Bit Score: 41.19  E-value: 8.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  19 DRAAFRNIYSRTSAKLFGVILRVLDDR-AEAEDVLQDVYVKVWNNADRYRANglSPMT-WLISIARNAAIDR-KRRARHS 95
Cdd:PRK12536   19 DAAAYRQFLSELAAHLRGFLRRRLPQLpDEVEDLVQEILLAVHNARHTYRAD--QPLTaWVHAIARYKLMDFlRSRARRE 96


                  ....*.
gi 1024540699  96 TTGDVL 101
Cdd:PRK12536   97 ALHDPL 102
PRK12523 PRK12523
RNA polymerase sigma factor; Reviewed
 34-178 1.60e-04

RNA polymerase sigma factor; Reviewed


Pssm-ID: 183572 [Multi-domain]  Cd Length: 172  Bit Score: 40.22  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  34 LFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANglSPMTWLISIARNAAIDRKRRA--RHSTTGDVLTATLADpAPG 111
Cdd:PRK12523   23 LLAWLRRNVACRQRAEDLSQDTFVRLLGRPELPTPR--EPRAFLAAVAKGLMFDHFRRAalEQAYLAELALVPEAE-QPS 99

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1024540699 112 PETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSllkLREC 178
Cdd:PRK12523  100 PEEQHLILEDLKAIDRLLGKLSSKARAAFLYNRLDGMGHAEIAERLGVSVSRVRQYLAQG---LRQC 163
PRK12527 PRK12527
RNA polymerase sigma factor; Reviewed
 42-159 1.66e-04

RNA polymerase sigma factor; Reviewed


Pssm-ID: 171560 [Multi-domain]  Cd Length: 159  Bit Score: 40.14  E-value: 1.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  42 LDDRAEAEDVLQDVYVKVWNNADRYRANglSPMTWLISIARNAAIDRKRR--ARHSTTGDVLTATLADPAPGPETMAIQS 119
Cdd:PRK12527   16 LGNRQAAEDVAHDAYLRVLERSSSAQIE--HPRAFLYRTALNLVVDRHRRhrVRQAEPLEVLDEEERLHSPSPQTRLDLG 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1024540699 120 SERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNV 159
Cdd:PRK12527   94 QRLALLQRALAELPPACRDSFLLRKLEGLSHQQIAEHLGI 133
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
 122-175 3.77e-04

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 37.05  E-value: 3.77e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1024540699 122 RSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKL 175
Cdd:pfam08281   1 LEALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
PRK12516 PRK12516
RNA polymerase sigma factor; Provisional
 31-179 4.04e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 183568 [Multi-domain]  Cd Length: 187  Bit Score: 39.18  E-value: 4.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  31 SAKLFGVILRVLDDRAEaeDVLQDVYVKVWNNADRYRAnGLSPMTWLISIARNAAID--RKRRARHSTTGDVLTATLADP 108
Cdd:PRK12516   22 SLRAFAVSLIGRHDRAD--DLVQDTIMKAWAKQDHFEV-GTNMKAWLFTILRNEFYSqmRKRGREVQDTDGMFTEQLAVH 98

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1024540699 109 APGPETMAIQSSeRSRLDgcfgELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK12516   99 PSQYGTLDLQDF-RAALD----QLPDDQREAIILVGASGFAYEEAAEICGCAVGTIKSRVNRARQRLQEIL 164
PRK12522 PRK12522
RNA polymerase sigma factor; Provisional
 34-179 4.49e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 183571 [Multi-domain]  Cd Length: 173  Bit Score: 39.08  E-value: 4.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  34 LFGVILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAIDRKRRAR----------HSTTGDVLTa 103
Cdd:PRK12522   16 IYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVE-NYKKWITTICVRTFYDFYRKKKrwkdrildlfHKEDGGEIE- 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1024540699 104 tLADPAPGPETMaIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECL 179
Cdd:PRK12522   94 -FADDVNISEEF-IQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKQMREHL 167
PRK09648 PRK09648
RNA polymerase sigma factor ShbA;
7-125 5.18e-04

RNA polymerase sigma factor ShbA;


Pssm-ID: 236607 [Multi-domain]  Cd Length: 189  Bit Score: 39.18  E-value: 5.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   7 EIEDLIARMALRDRAAFRNI----------YSRTSaklfgvILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPMTW 76
Cdd:PRK09648   10 ELDALVAEAVAGDRRALREVleiirplvvrYCRAR------LGGVERPGLSADDVAQEVCLAVITALPRYRDQGRPFLAF 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1024540699  77 LISIARNAAIDRKRRA-RHSTtgdVLTATL---ADPAPGPETMAIQSSERSRL 125
Cdd:PRK09648   84 VYGIAAHKVADAHRAAgRDKA---VPTEEVperPSDDAGPEERALRSESSNRM 133
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
 40-181 7.95e-04

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 38.61  E-value: 7.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  40 RVLDDRAEAEDVLQDVYVKVWNNADRYranglSPMT---WLISIARNAAIDRKRRaRHSTTGDVLTATlADPAPGPETMA 116
Cdd:PRK09647   47 RLSGNQHDAEDLTQETFIRVFRSLQNY-----QPGTfegWLHRITTNLFLDMVRR-RARIRMEALPED-YDRVPGDEPNP 119

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1024540699 117 IQSSERSRLDGCFGE-LDQQHAD---AVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRECLSR 181
Cdd:PRK09647  120 EQIYHDARLDPDLQAaLDSLPPEfraAVVLCDIEGLSYEEIAATLGVKLGTVRSRIHRGRQQLRAALAA 188
PRK12512 PRK12512
RNA polymerase sigma factor; Provisional
 19-175 8.15e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 171551 [Multi-domain]  Cd Length: 184  Bit Score: 38.53  E-value: 8.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  19 DRAAFRNIYSRTSAKLFGVILRVLDdRA-----EAEDVLQDVYVKVWNNADRYRANG-LSPmtWLISIARNAAIDR-KRR 91
Cdd:PRK12512   20 DAAAYRRLLKAVTPVLRAAARRGLA-RAgqpadQAEDIVQEILLAVHLKRHTWDPGApFAP--WLFAIARNKLIDAlRRR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  92 ARHSTTG-DVLTATLADPAPGPetmaiqSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRR 170
Cdd:PRK12512   97 GRRVFVDiDDFAETLPAEPATE------TLPAGDVGRHLETLPPRQRDVVQSISVEGASIKETAAKLSMSEGAVRVALHR 170


                  ....*
gi 1024540699 171 SLLKL 175
Cdd:PRK12512  171 GLAAL 175
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
 18-96 1.01e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 38.11  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  18 RDRAAFRNIYSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNADR-YRANGLSPMTWLISIARNAAIDRKRR-ARHS 95
Cdd:PRK12542    6 NDYEKMEELYELYEQKVYYVAYSILNNIQQAEDAVQETFITLYKNLEKlHSLNTQELKRYILRVAKNKAIDSYRKnKRHE 85


                  .
gi 1024540699  96 T 96
Cdd:PRK12542   86 T 86
PRK12525 PRK12525
RNA polymerase sigma factor; Provisional
 23-172 1.31e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 139037 [Multi-domain]  Cd Length: 168  Bit Score: 37.62  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  23 FRNIYSRTSAKLfgviLRVLDDRAEAEDVLQDVYVKVWNNADRyrANGLSPMTWLISIARNAAIDRKRRArhsttgDVLT 102
Cdd:PRK12525   15 FQQDYDWLCKKL----SRQLGCPHSAEDIASETFLQVLALPDP--ASIREPRALLTTIARRLMYEGWRRQ------DLER 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1024540699 103 ATLADPAPGPETMAIQSSERS-------RLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSL 172
Cdd:PRK12525   83 AYLQSLAEAPEAVQPSPEEQWmvietllAIDRLLDGLSGKARAAFLMSQLEGLTYVEIGERLGVSLSRIHQYMVEAF 159
PRK12535 PRK12535
RNA polymerase sigma factor; Provisional
 8-171 1.84e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 237130 [Multi-domain]  Cd Length: 196  Bit Score: 37.57  E-value: 1.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   8 IEDLIARMALRDRAAFRNIYSRTSAKLFGvILRVLDDRAEAEDVLQDVYVKVWNNADRYRANGlSPMTWLISIARNAAID 87
Cdd:PRK12535   12 VTDLALAAGRGDRAALTEFIRETQDDVWR-LLAHLGGHDIADDLTQETYLRVMSALPRFAARS-SARTWLLSLARRVWVD 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  88 RKR----RARHSTTgDVLTATLADPAPGPETMAiqsSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNT 163
Cdd:PRK12535   90 NIRhdmaRPRKSAT-EYEDAAATTASNETTGSW---SEWIDVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRVGT 165


                  ....*...
gi 1024540699 164 MRTWLRRS 171
Cdd:PRK12535  166 IRSRVARA 173
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
 39-181 2.14e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 37.22  E-value: 2.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  39 LRVLDDRAEAEDVLQDVYVKVWNNADRYRANGLSPmTWLISIARNAAIDRKR-RARHSTTGDVLTATLADPA-------- 109
Cdd:PRK12532   24 LQLPDHPDLAEDLVQETLLSAYSAGDSFQGRALVN-SWLFAILKNKIIDALRqIGRQRKVFTLLDDELLDEAfeshfsqn 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 110 ------------PGPETMAIQSSERSRLDGCFGELDQQHADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRRSLLKLRE 177
Cdd:PRK12532  103 ghwtpegqpqhwNTPEKSLNNNEFQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQMCGISTSNYHTIMHRARESLRQ 182


                  ....
gi 1024540699 178 CLSR 181
Cdd:PRK12532  183 CLQI 186
PRK12539 PRK12539
RNA polymerase sigma factor SigF;
1-159 4.94e-03

RNA polymerase sigma factor SigF;


Pssm-ID: 237132 [Multi-domain]  Cd Length: 184  Bit Score: 36.25  E-value: 4.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699   1 MSSELLEIEDLIARMALRDRAAFRNIYSRTSAKLF----GVILRVLDDRAEAEDVLQDVYVKVwnNADRYRANGLSPMT- 75
Cdd:PRK12539    1 MMSQENELKALMLASLDGDAAAHRALLERLSGHLRayykGKLARIGRGAEEAEDLVQEALMAI--HTRRHTYDPEQPLTp 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  76 WLISIARNAAIDRKRRARHSTTgDVLTATLADPAPGPETMAIQSS-ERSRLdgcFGELDQQHADAVRRAYLEGDTYAELA 154
Cdd:PRK12539   79 WVYAIARYKLIDHLRRTRASLA-DVPIDDADELVAHDDHAAVESTlDLGRL---LARLPEKMRLAIQAVKLEGLSVAEAA 154


                  ....*
gi 1024540699 155 ERYNV 159
Cdd:PRK12539  155 TRSGM 159
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
137-170 5.24e-03

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 34.90  E-value: 5.24e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1024540699 137 ADAVRRAYLEGDTYAELAERYNVPLNTMRTWLRR 170
Cdd:COG2963    14 AEAVRLVLEGGASVAEVARELGISPSTLYRWVRQ 47
sigI PRK09635
RNA polymerase sigma factor SigI; Provisional
 27-177 8.43e-03

RNA polymerase sigma factor SigI; Provisional


Pssm-ID: 182008 [Multi-domain]  Cd Length: 290  Bit Score: 35.71  E-value: 8.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  27 YSRTSAKLFGVILRVLDDRAEAEDVLQDVYVKVWNNA----DRYRAnglspmtWLISIARNAAID--RKRRARHSTTGDV 100
Cdd:PRK09635   11 WRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAPvgdiDDERG-------WLIVVTSRLCLDhiKSASTRRERPQDI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 101 LTATLADPAPGpetmAIQSSERSRLDgcfgeldqqhaDAVRRAYLE-------------------GDTYAELAERYNVPL 161
Cdd:PRK09635   84 AAWHDGDASVS----SVDPADRVTLD-----------DEVRLALLImlerlgpaervvfvlheifGLPYQQIATTIGSQA 148

                         170
                  ....*....|....*.
gi 1024540699 162 NTMRTWLRRSLLKLRE 177
Cdd:PRK09635  149 STCRQLAHRARRKINE 164
PRK12530 PRK12530
RNA polymerase sigma factor; Provisional
 42-181 9.00e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 237128 [Multi-domain]  Cd Length: 189  Bit Score: 35.51  E-value: 9.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699  42 LDDRAEAEDVLQDVYVKVWNNADRYRanGLSPM-TWLISIARNAAIDR-KRRARHSTTGDVLTATL------------AD 107
Cdd:PRK12530   28 LKDADLAEDVVQEALVSAYKNADSFK--GQSALkTWIFAILKNKIIDLiRYRKRFVNESELIEEDSpnsffdekghwkPE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024540699 108 PAPGPETMAIQSSERSR-----LDGCFGELDQQHADA-VRRAYLEGDTyAELAERYNVPLNTMRTWLRRSLLKLRECLSR 181
Cdd:PRK12530  106 YYEPSEWQEVENTVYKEefwliFEACLNHLPAQQARVfMMREYLELSS-EQICQECDISTSNLHVLLYRARLQLQACLSK 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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