NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|115311558|ref|NP_001020255|]
View 

reproductive homeobox 1 [Mus musculus]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10052840)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

Gene Ontology:  GO:0003677|GO:0006357|GO:0043565
PubMed:  1357790|26464018|21557080

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Homeodomain super family cl47488
Homeodomain;
184-220 2.08e-07

Homeodomain;


The actual alignment was detected with superfamily member pfam00046:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 46.34  E-value: 2.08e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 115311558  184 RTQYISAQDRKRLAVCLCVCEAKVQNWFQRRRAEYRK 220
Cdd:pfam00046  21 ENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
184-220 2.08e-07

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 46.34  E-value: 2.08e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 115311558  184 RTQYISAQDRKRLAVCLCVCEAKVQNWFQRRRAEYRK 220
Cdd:pfam00046  21 ENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 184-220 5.00e-07

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 45.31  E-value: 5.00e-07
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 115311558 184 RTQYISAQDRKRLAVCLCVCEAKVQNWFQRRRAEYRK 220
Cdd:cd00086   21 KNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 184-219 1.13e-05

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 41.85  E-value: 1.13e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 115311558   184 RTQYISAQDRKRLAVCLCVCEAKVQNWFQRRRAEYR 219
Cdd:smart00389  22 KNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
184-220 2.08e-07

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 46.34  E-value: 2.08e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 115311558  184 RTQYISAQDRKRLAVCLCVCEAKVQNWFQRRRAEYRK 220
Cdd:pfam00046  21 ENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 184-220 5.00e-07

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 45.31  E-value: 5.00e-07
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 115311558 184 RTQYISAQDRKRLAVCLCVCEAKVQNWFQRRRAEYRK 220
Cdd:cd00086   21 KNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 184-219 1.13e-05

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 41.85  E-value: 1.13e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 115311558   184 RTQYISAQDRKRLAVCLCVCEAKVQNWFQRRRAEYR 219
Cdd:smart00389  22 KNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH