NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|71989915|ref|NP_001022187|]
View 

Serpentine receptor class alpha-13 [Caenorhabditis elegans]

Protein Classification

class alpha serpentine receptor( domain architecture ID 140224)

class alpha serpentine receptor (Sra) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Sra super family cl20025
Serpentine type 7TM GPCR chemoreceptor Sra; Chemoreception is mediated in Caenorhabditis ...
 23-170 4.79e-22

Serpentine type 7TM GPCR chemoreceptor Sra; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sra is part of the Sra superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


The actual alignment was detected with superfamily member pfam02117:

Pssm-ID: 111054  Cd Length: 328  Bit Score: 90.48  E-value: 4.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989915    23 NRTCASESLLELYRSYKYILSTSFNIIIPIISLFFLVYAIKQLCAQSIIQYSTRVLLITTILFAVCHQIAYFCFKADLLY 102
Cdd:pfam02117   3 NPKCASEDEIDRLSSLNFRIAQFIDLIAIIITFILTYFAIKIVFKKSIFQLSTKILLFQNLFYANLHQIFYGIEAIRMLY 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71989915   103 TMLFKLDQPCNLQHSSYDCRFITIATTTSNCGMALVQLAMSIDRVFALKFNRVYYKLKSIPGITLALI 170
Cdd:pfam02117  83 KSFFMLSEPCNILITEIDCAPYLEVLVAGISGMIYGQTGLLIERACATFIKKYKKKKSALPGVIISIL 150
 
Name Accession Description Interval E-value
7TM_GPCR_Sra pfam02117
Serpentine type 7TM GPCR chemoreceptor Sra; Chemoreception is mediated in Caenorhabditis ...
 23-170 4.79e-22

Serpentine type 7TM GPCR chemoreceptor Sra; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sra is part of the Sra superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 111054  Cd Length: 328  Bit Score: 90.48  E-value: 4.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989915    23 NRTCASESLLELYRSYKYILSTSFNIIIPIISLFFLVYAIKQLCAQSIIQYSTRVLLITTILFAVCHQIAYFCFKADLLY 102
Cdd:pfam02117   3 NPKCASEDEIDRLSSLNFRIAQFIDLIAIIITFILTYFAIKIVFKKSIFQLSTKILLFQNLFYANLHQIFYGIEAIRMLY 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71989915   103 TMLFKLDQPCNLQHSSYDCRFITIATTTSNCGMALVQLAMSIDRVFALKFNRVYYKLKSIPGITLALI 170
Cdd:pfam02117  83 KSFFMLSEPCNILITEIDCAPYLEVLVAGISGMIYGQTGLLIERACATFIKKYKKKKSALPGVIISIL 150
 
Name Accession Description Interval E-value
7TM_GPCR_Sra pfam02117
Serpentine type 7TM GPCR chemoreceptor Sra; Chemoreception is mediated in Caenorhabditis ...
 23-170 4.79e-22

Serpentine type 7TM GPCR chemoreceptor Sra; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sra is part of the Sra superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 111054  Cd Length: 328  Bit Score: 90.48  E-value: 4.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71989915    23 NRTCASESLLELYRSYKYILSTSFNIIIPIISLFFLVYAIKQLCAQSIIQYSTRVLLITTILFAVCHQIAYFCFKADLLY 102
Cdd:pfam02117   3 NPKCASEDEIDRLSSLNFRIAQFIDLIAIIITFILTYFAIKIVFKKSIFQLSTKILLFQNLFYANLHQIFYGIEAIRMLY 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71989915   103 TMLFKLDQPCNLQHSSYDCRFITIATTTSNCGMALVQLAMSIDRVFALKFNRVYYKLKSIPGITLALI 170
Cdd:pfam02117  83 KSFFMLSEPCNILITEIDCAPYLEVLVAGISGMIYGQTGLLIERACATFIKKYKKKKSALPGVIISIL 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH