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Conserved domains on  [gi|86575043|ref|NP_001033436|]
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Transcription factor elt-1 [Caenorhabditis elegans]

Protein Classification

GATA-type transcription factor( domain architecture ID 10078896)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
Gene Ontology:  GO:0003700|GO:0006357|GO:0008270|GO:0043565
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 271-322 3.77e-20

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 83.19  E-value: 3.77e-20
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 86575043 271 ECVNCRTNTTTLWRRNG-EGHPVCNACGLYFKLHKVERPITMKK-DGIQTRNRK 322
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 216-267 6.15e-20

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 82.81  E-value: 6.15e-20
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 86575043 216 ECVNCGVHNTPLWRRDGS-GNYLCNACGLYFKMNHHARPLVKPKKRQQNAQKR 267
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDQIKRRNR 53
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 271-322 3.77e-20

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 83.19  E-value: 3.77e-20
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 86575043 271 ECVNCRTNTTTLWRRNG-EGHPVCNACGLYFKLHKVERPITMKK-DGIQTRNRK 322
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 216-267 6.15e-20

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 82.81  E-value: 6.15e-20
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 86575043 216 ECVNCGVHNTPLWRRDGS-GNYLCNACGLYFKMNHHARPLVKPKKRQQNAQKR 267
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDQIKRRNR 53
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
213-260 1.54e-16

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 73.22  E-value: 1.54e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 86575043    213 EDRECVNCGVHNTPLWRRDGSGN-YLCNACGLYFKM-NHHARPLVKPKKR 260
Cdd:smart00401   2 SGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKhGGLKRPLSLKKDG 51
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
267-316 2.09e-16

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 72.84  E-value: 2.09e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 86575043    267 RTGIECVNCRTNTTTLWRRNGEGH-PVCNACGLYFKLH-KVERPITMKKDGI 316
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHgGLKRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 217-250 5.52e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 62.72  E-value: 5.52e-13
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 86575043   217 CVNCGVHNTPLWRRDGSGNY-LCNACGLYFKMNHH 250
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 272-305 3.87e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 60.41  E-value: 3.87e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 86575043   272 CVNCRTNTTTLWRRNGEGHP-VCNACGLYFKLHKV 305
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
272-327 1.19e-07

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 53.72  E-value: 1.19e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 86575043 272 CVNCRTNTTTLWRRNGE-----GHPVCNACGLYFKLHKVER-PITMKKDGIQTRNRKLSAKG 327
Cdd:COG5641 161 CSNCKTTSTPLWRRASSesslpGNNLCNACGLYLKLHGSPRaPISLKSDSIKSRSSRSSHNN 222
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 271-322 3.77e-20

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 83.19  E-value: 3.77e-20
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 86575043 271 ECVNCRTNTTTLWRRNG-EGHPVCNACGLYFKLHKVERPITMKK-DGIQTRNRK 322
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 216-267 6.15e-20

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 82.81  E-value: 6.15e-20
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 86575043 216 ECVNCGVHNTPLWRRDGS-GNYLCNACGLYFKMNHHARPLVKPKKRQQNAQKR 267
Cdd:cd00202   1 ACSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDQIKRRNR 53
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
213-260 1.54e-16

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 73.22  E-value: 1.54e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 86575043    213 EDRECVNCGVHNTPLWRRDGSGN-YLCNACGLYFKM-NHHARPLVKPKKR 260
Cdd:smart00401   2 SGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKhGGLKRPLSLKKDG 51
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
267-316 2.09e-16

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 72.84  E-value: 2.09e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 86575043    267 RTGIECVNCRTNTTTLWRRNGEGH-PVCNACGLYFKLH-KVERPITMKKDGI 316
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHgGLKRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 217-250 5.52e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 62.72  E-value: 5.52e-13
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 86575043   217 CVNCGVHNTPLWRRDGSGNY-LCNACGLYFKMNHH 250
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 272-305 3.87e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 60.41  E-value: 3.87e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 86575043   272 CVNCRTNTTTLWRRNGEGHP-VCNACGLYFKLHKV 305
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
272-327 1.19e-07

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 53.72  E-value: 1.19e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 86575043 272 CVNCRTNTTTLWRRNGE-----GHPVCNACGLYFKLHKVER-PITMKKDGIQTRNRKLSAKG 327
Cdd:COG5641 161 CSNCKTTSTPLWRRASSesslpGNNLCNACGLYLKLHGSPRaPISLKSDSIKSRSSRSSHNN 222
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
191-301 2.09e-06

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 49.87  E-value: 2.09e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86575043 191 PKNTISKANRSSGgANNSQFSTEDRECVNCGVHNTPLWRRDGS-----GNYLCNACGLYFKMNHHARPLVKPKKRQQNAQ 265
Cdd:COG5641 136 TLNPGGTSSLNPN-NNQSDNSNQPHVCSNCKTTSTPLWRRASSesslpGNNLCNACGLYLKLHGSPRAPISLKSDSIKSR 214

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 86575043 266 KRTGIECVNCRTNTTTLWRRNGEGHPVCNACGLYFK 301
Cdd:COG5641 215 SSRSSHNNNDSNGENANTESIGNSSASKLTKSWEER 250
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
191-327 9.66e-04

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 41.40  E-value: 9.66e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 86575043 191 PKNTISKANRSSG-GANNSQFST---EDRECVNCGVHN-TPLWRR-DGSGNYLCNACGLYFKMNHHARPLvkPKKRQQNA 264
Cdd:COG5641 270 PKSPLLEGLMGSTsLQPVSTPKLvlpSDKKRSTLTTSTaTPLWRRtSDKSSFSCNASGSALKPPGSKRPL--LPKPDPNS 347

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86575043 265 QKRTGIeCVNCRTNTTTLWRrngEGHPVCNACGLYFKLHKVERPITMKKDGIqTRNRKLSAKG 327
Cdd:COG5641 348 KRSNAT-CMNCSSTPTNKIL---SPPTTSNSPGAQVKLPNQTRSTGATKKKI-TRRRMNSGKI 405
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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