NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|89242160|ref|NP_001034785|]
View 

reproductive homeobox 4F [Mus musculus]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10052840)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

Gene Ontology:  GO:0003677|GO:0006357|GO:0043565
PubMed:  1357790|26464018|21557080

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 129-187 1.63e-12

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


:

Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 59.95  E-value: 1.63e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 89242160 129 RSLHYNFQWWQLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRREHFRRGQ 187
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 129-187 1.63e-12

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 59.95  E-value: 1.63e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 89242160 129 RSLHYNFQWWQLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRREHFRRGQ 187
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
Homeodomain pfam00046
Homeodomain;
139-185 8.72e-12

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 57.90  E-value: 8.72e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 89242160   139 QLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRREHFRR 185
Cdd:pfam00046  11 QLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 139-180 1.86e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 54.56  E-value: 1.86e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 89242160    139 QLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRR 180
Cdd:smart00389  12 QLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRR 53
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
138-202 2.74e-04

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 39.73  E-value: 2.74e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 89242160 138 WQLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRReHFRRGQSQLGMNDDAPVGSHS 202
Cdd:COG5576  61 EQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKR-AKEKKKRSGKVEQRPGEEEAD 124
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 129-187 1.63e-12

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 59.95  E-value: 1.63e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 89242160 129 RSLHYNFQWWQLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRREHFRRGQ 187
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
Homeodomain pfam00046
Homeodomain;
139-185 8.72e-12

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 57.90  E-value: 8.72e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 89242160   139 QLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRREHFRR 185
Cdd:pfam00046  11 QLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 139-180 1.86e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 54.56  E-value: 1.86e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 89242160    139 QLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRR 180
Cdd:smart00389  12 QLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRR 53
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
138-202 2.74e-04

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 39.73  E-value: 2.74e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 89242160 138 WQLQELERIFQQNHFIRAEERRHLARWIGVSEARVMTWFKKRReHFRRGQSQLGMNDDAPVGSHS 202
Cdd:COG5576  61 EQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKR-AKEKKKRSGKVEQRPGEEEAD 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH