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Conserved domains on  [gi|124487457|ref|NP_001074593|]
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MAP7 domain-containing protein 2 isoform 1 [Mus musculus]

Protein Classification

MAP7 domain-containing protein( domain architecture ID 12064852)

MAP7 domain-containing protein such as MAP7D1 (microtubule-associated protein 7 domain containing 1) identified as a novel substrate of doublecortin-like kinase 1 (DCLK1)

Gene Ontology:  GO:0005737

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 438-603 3.56e-21

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


:

Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 90.49  E-value: 3.56e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  438 KPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEmaykreqekkrqeeEEKRKA 517
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARRE--------------EEARRL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  518 EEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRT 597
Cdd:pfam05672  67 EEERRREEEERQRKAEEEAEEREQREQEEQERLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKRT 146


                  ....*.
gi 124487457  598 RKSDAS 603
Cdd:pfam05672 147 RKSDQA 152
DUF5401 super family cl38662
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 75-168 3.58e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


The actual alignment was detected with superfamily member pfam17380:

Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.51  E-value: 3.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERREEREKCLAAREQQILEKQKRAKLqYEKQIEERWRKLEEqrqrEDQKRAAVEEKRKQKLREEEERLEAMMR 154
Cdd:pfam17380 485 DRKRAEEQRRKILEKELEERKQAMIEEERKRKL-LEKEMEERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMR 559

                          90
                  ....*....|....
gi 124487457  155 RSLERTQQLELKKK 168
Cdd:pfam17380 560 KATEERSRLEAMER 573
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 438-603 3.56e-21

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 90.49  E-value: 3.56e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  438 KPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEmaykreqekkrqeeEEKRKA 517
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARRE--------------EEARRL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  518 EEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRT 597
Cdd:pfam05672  67 EEERRREEEERQRKAEEEAEEREQREQEEQERLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKRT 146


                  ....*.
gi 124487457  598 RKSDAS 603
Cdd:pfam05672 147 RKSDQA 152
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 75-168 3.58e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.51  E-value: 3.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERREEREKCLAAREQQILEKQKRAKLqYEKQIEERWRKLEEqrqrEDQKRAAVEEKRKQKLREEEERLEAMMR 154
Cdd:pfam17380 485 DRKRAEEQRRKILEKELEERKQAMIEEERKRKL-LEKEMEERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMR 559

                          90
                  ....*....|....
gi 124487457  155 RSLERTQQLELKKK 168
Cdd:pfam17380 560 KATEERSRLEAMER 573
PTZ00121 PTZ00121
MAEBL; Provisional
 47-168 1.54e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   47 AKSAEAASGRASQSTPRSagmDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYE---KQIEERWRKLEEQ 123
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKA---DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEeakKKADAAKKKAEEK 1390

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 124487457  124 RQREDQKRAAVEEKRK----QKLREEEERLEAMMRRSLERTQQLELKKK 168
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKadelKKAAAAKKKADEAKKKAEEKKKADEAKKK 1439
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 75-168 3.36e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 40.60  E-value: 3.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERREEREkclaAREQQILEKQKRAKLQYEKQIEERWRKLEEQR-QREDQKRAAVEEKRKQKLREEEERLEAMM 153
Cdd:TIGR02794  66 EQERQKKLEQQAEE----AEKQRAAEQARQKELEQRAAAEKAAKQAEQAAkQAEEKQKQAEEAKAKQAAEAKAKAEAEAE 141

                          90
                  ....*....|....*.
gi 124487457  154 RRSLERTQ-QLELKKK 168
Cdd:TIGR02794 142 RKAKEEAAkQAEEEAK 157
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
75-164 5.85e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.14  E-value: 5.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  75 ERQRLAKERREEREKCLAAREQQILEKQKRAKLQyekQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMR 154
Cdd:COG4717  109 AELEELREELEKLEKLLQLLPLYQELEALEAELA---ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                         90
                 ....*....|
gi 124487457 155 RSLERTQQLE 164
Cdd:COG4717  186 LSLATEEELQ 195
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 438-603 3.56e-21

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 90.49  E-value: 3.56e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  438 KPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEmaykreqekkrqeeEEKRKA 517
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARRE--------------EEARRL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  518 EEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRT 597
Cdd:pfam05672  67 EEERRREEEERQRKAEEEAEEREQREQEEQERLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKRT 146


                  ....*.
gi 124487457  598 RKSDAS 603
Cdd:pfam05672 147 RKSDQA 152
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 75-168 3.58e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.51  E-value: 3.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERREEREKCLAAREQQILEKQKRAKLqYEKQIEERWRKLEEqrqrEDQKRAAVEEKRKQKLREEEERLEAMMR 154
Cdd:pfam17380 485 DRKRAEEQRRKILEKELEERKQAMIEEERKRKL-LEKEMEERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMR 559

                          90
                  ....*....|....
gi 124487457  155 RSLERTQQLELKKK 168
Cdd:pfam17380 560 KATEERSRLEAMER 573
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 75-162 6.08e-04

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 41.18  E-value: 6.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERREEREKclaAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAvEEKRKQKLREEEERLEAMMR 154
Cdd:pfam05672  18 EKRRQAREQREREEQ---ERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRRE-EEERQRKAEEEAEEREQREQ 93


                  ....*...
gi 124487457  155 RSLERTQQ 162
Cdd:pfam05672  94 EEQERLQK 101
ARGLU pfam15346
Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is ...
 75-168 9.41e-04

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.


Pssm-ID: 405931 [Multi-domain]  Cd Length: 151  Bit Score: 40.42  E-value: 9.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERRE--EREKCLAAREQQILEKQKRAKL-QYEKQIEERWRKLEE-QRQREDQKRAAVEEKRKQKlrEEEERLE 150
Cdd:pfam15346  46 ARKIMEKQVLEelEREREAELEEERRKEEEERKKReELERILEENNRKIEEaQRKEAEERLAMLEEQRRMK--EERQRRE 123

                          90
                  ....*....|....*...
gi 124487457  151 AMMRRSLERTQQLELKKK 168
Cdd:pfam15346 124 KEEEEREKREQQKILNKK 141
PTZ00121 PTZ00121
MAEBL; Provisional
 47-168 1.54e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   47 AKSAEAASGRASQSTPRSagmDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYE---KQIEERWRKLEEQ 123
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKA---DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEeakKKADAAKKKAEEK 1390

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 124487457  124 RQREDQKRAAVEEKRK----QKLREEEERLEAMMRRSLERTQQLELKKK 168
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKadelKKAAAAKKKADEAKKKAEEKKKADEAKKK 1439
PTZ00121 PTZ00121
MAEBL; Provisional
 47-168 1.87e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 1.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   47 AKSAEAASGRASQ----STPRSAGMDGFLKSDERQRLAKE-RREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLE 121
Cdd:PTZ00121 1612 AKKAEEAKIKAEElkkaEEEKKKVEQLKKKEAEEKKKAEElKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA 1691

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 124487457  122 EQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKK 168
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE 1738
DDRGK pfam09756
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 72-141 2.08e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 40.02  E-value: 2.08e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   72 KSDERQRLAKERREEREKclaarEQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQK 141
Cdd:pfam09756   6 KKRAKLELKEAKRQQREA-----EEEEREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQERK 70
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 74-141 2.34e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 41.06  E-value: 2.34e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 124487457   74 DERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQK 141
Cdd:pfam13868  58 EEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQ 125
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 75-168 3.36e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 40.60  E-value: 3.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERREEREkclaAREQQILEKQKRAKLQYEKQIEERWRKLEEQR-QREDQKRAAVEEKRKQKLREEEERLEAMM 153
Cdd:TIGR02794  66 EQERQKKLEQQAEE----AEKQRAAEQARQKELEQRAAAEKAAKQAEQAAkQAEEKQKQAEEAKAKQAAEAKAKAEAEAE 141

                          90
                  ....*....|....*.
gi 124487457  154 RRSLERTQ-QLELKKK 168
Cdd:TIGR02794 142 RKAKEEAAkQAEEEAK 157
PTZ00121 PTZ00121
MAEBL; Provisional
 35-168 3.82e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 3.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   35 SEGAAKGLSLLLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQyeKQIE 114
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAK--KKAE 1401

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 124487457  115 ERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEammRRSLERTQQLELKKK 168
Cdd:PTZ00121 1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK---KKAEEAKKADEAKKK 1452
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 75-168 4.89e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 4.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   75 ERQRLAKERREER--EKCLAAREQQILEKQKRAKLQYEKQI------------EERWRKLEEQRQREDQKRAAVEEKRKQ 140
Cdd:pfam17380 381 ERLQMERQQKNERvrQELEAARKVKILEEERQRKIQQQKVEmeqiraeqeearQREVRRLEEERAREMERVRLEEQERQQ 460

                          90       100
                  ....*....|....*....|....*...
gi 124487457  141 KLREEEERLEAMMRRSLERTQQLELKKK 168
Cdd:pfam17380 461 QVERLRQQEEERKRKKLELEKEKRDRKR 488
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 74-140 5.31e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 39.90  E-value: 5.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   74 DERQRLAKERREEREKCLA---AREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQ 140
Cdd:pfam13868  40 EEERRLDEMMEEERERALEeeeEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVER 109
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
75-164 5.85e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.14  E-value: 5.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457  75 ERQRLAKERREEREKCLAAREQQILEKQKRAKLQyekQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMR 154
Cdd:COG4717  109 AELEELREELEKLEKLLQLLPLYQELEALEAELA---ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                         90
                 ....*....|
gi 124487457 155 RSLERTQQLE 164
Cdd:COG4717  186 LSLATEEELQ 195
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 72-141 6.77e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.11  E-value: 6.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   72 KSDERQRLAKERREEREKCLAA---REQQIL------EKQKRAKLQYEKQIEERWRKLEEQR-----QREDQKRAAVEEK 137
Cdd:pfam17380 433 RQREVRRLEEERAREMERVRLEeqeRQQQVErlrqqeEERKRKKLELEKEKRDRKRAEEQRRkilekELEERKQAMIEEE 512


                  ....
gi 124487457  138 RKQK 141
Cdd:pfam17380 513 RKRK 516
PTZ00121 PTZ00121
MAEBL; Provisional
 72-168 7.45e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 7.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   72 KSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEA 151
Cdd:PTZ00121 1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                          90
                  ....*....|....*..
gi 124487457  152 MMRRSLERTQQLELKKK 168
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKK 1547
PTZ00121 PTZ00121
MAEBL; Provisional
 78-167 8.18e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   78 RLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSL 157
Cdd:PTZ00121 1662 KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741

                          90
                  ....*....|
gi 124487457  158 ERTQQLELKK 167
Cdd:PTZ00121 1742 DKKKAEEAKK 1751
DDRGK pfam09756
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 76-129 8.42e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 38.10  E-value: 8.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 124487457   76 RQRLAKER-REEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQ 129
Cdd:pfam09756  19 QQREAEEEeREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQERKEQE 73
PTZ00121 PTZ00121
MAEBL; Provisional
 72-164 9.61e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 9.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487457   72 KSDERQRLAKERREEREKCLAAREQQILEK--QKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERL 149
Cdd:PTZ00121 1559 KAEEKKKAEEAKKAEEDKNMALRKAEEAKKaeEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQL 1638

                          90
                  ....*....|....*
gi 124487457  150 EAMMRRSLERTQQLE 164
Cdd:PTZ00121 1639 KKKEAEEKKKAEELK 1653
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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