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Conserved domains on  [gi|145332709|ref|NP_001078220|]
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myb domain protein 110 [Arabidopsis thaliana]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 1000535)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein may be involved in the regulation of gene expression

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN03212 super family cl31985
Transcription repressor MYB5; Provisional
67-171 5.25e-22

Transcription repressor MYB5; Provisional


The actual alignment was detected with superfamily member PLN03212:

Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 92.45  E-value: 5.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332709  67 RGHWRISEDTQLMELVSVYGPQNWNHIAESMQG-RTGKSCRLRWFNQLDPRINKRAFSDEEEERLLAAHRAFGNKWAMIA 145
Cdd:PLN03212  25 RGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLlRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLIA 104
                         90       100
                 ....*....|....*....|....*.
gi 145332709 146 KLFNGRTDNALKNHWHVLMARKMRQQ 171
Cdd:PLN03212 105 GRIPGRTDNEIKNYWNTHLRKKLLRQ 130
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
67-171 5.25e-22

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 92.45  E-value: 5.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332709  67 RGHWRISEDTQLMELVSVYGPQNWNHIAESMQG-RTGKSCRLRWFNQLDPRINKRAFSDEEEERLLAAHRAFGNKWAMIA 145
Cdd:PLN03212  25 RGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLlRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLIA 104
                         90       100
                 ....*....|....*....|....*.
gi 145332709 146 KLFNGRTDNALKNHWHVLMARKMRQQ 171
Cdd:PLN03212 105 GRIPGRTDNEIKNYWNTHLRKKLLRQ 130
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
68-166 8.55e-17

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 80.22  E-value: 8.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332709  68 GHWRISEDTQLMELVSVYGPQNWNHIAESMQGRTGKSCRLRWFNQLDPRINKRAFSDEEEERLLAAHRAFGNKWAMIAKL 147
Cdd:COG5147   21 GSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWSTIADY 100
                         90
                 ....*....|....*....
gi 145332709 148 FNGRTDNALKNHWHVLMAR 166
Cdd:COG5147  101 KDRRTAQQCVERYVNTLED 119
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
119-161 5.63e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 59.44  E-value: 5.63e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 145332709  119 KRAFSDEEEERLLAAHRAFGNKWAMIAKLFNGRTDNALKNHWH 161
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
67-115 1.07e-09

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 53.38  E-value: 1.07e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 145332709    67 RGHWRISEDTQLMELVSVYGPQNWNHIAESMQGRTGKSCRLRWFNQLDP 115
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
70-111 1.56e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 52.58  E-value: 1.56e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 145332709  70 WRISEDTQLMELVSVYGPQNWNHIAESMQGRTGKSCRLRWFN 111
Cdd:cd00167    2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRN 43
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
67-171 5.25e-22

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 92.45  E-value: 5.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332709  67 RGHWRISEDTQLMELVSVYGPQNWNHIAESMQG-RTGKSCRLRWFNQLDPRINKRAFSDEEEERLLAAHRAFGNKWAMIA 145
Cdd:PLN03212  25 RGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLlRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLIA 104
                         90       100
                 ....*....|....*....|....*.
gi 145332709 146 KLFNGRTDNALKNHWHVLMARKMRQQ 171
Cdd:PLN03212 105 GRIPGRTDNEIKNYWNTHLRKKLLRQ 130
PLN03091 PLN03091
hypothetical protein; Provisional
67-171 1.51e-21

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 94.27  E-value: 1.51e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332709  67 RGHWRISEDTQLMELVSVYGPQNWNHIAE--SMQgRTGKSCRLRWFNQLDPRINKRAFSDEEEERLLAAHRAFGNKWAMI 144
Cdd:PLN03091  14 KGLWSPEEDEKLLRHITKYGHGCWSSVPKqaGLQ-RCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQI 92
                         90       100
                 ....*....|....*....|....*..
gi 145332709 145 AKLFNGRTDNALKNHWHVLMARKMRQQ 171
Cdd:PLN03091  93 AAQLPGRTDNEIKNLWNSCLKKKLRQR 119
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
68-166 8.55e-17

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 80.22  E-value: 8.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332709  68 GHWRISEDTQLMELVSVYGPQNWNHIAESMQGRTGKSCRLRWFNQLDPRINKRAFSDEEEERLLAAHRAFGNKWAMIAKL 147
Cdd:COG5147   21 GSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWSTIADY 100
                         90
                 ....*....|....*....
gi 145332709 148 FNGRTDNALKNHWHVLMAR 166
Cdd:COG5147  101 KDRRTAQQCVERYVNTLED 119
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
119-161 5.63e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 59.44  E-value: 5.63e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 145332709  119 KRAFSDEEEERLLAAHRAFGNKWAMIAKLFNGRTDNALKNHWH 161
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
70-130 1.07e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 59.25  E-value: 1.07e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 145332709   70 WRISEDTQLMELVSVYGpQNWNHIAESMQGRTGKSCRLRWFNQLDPRINKRAFSDEEEERL 130
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
67-113 1.08e-10

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 55.97  E-value: 1.08e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 145332709   67 RGHWRISEDTQLMELVSVYGPqNWNHIAESMQGRTGKSCRLRWFNQL 113
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
67-115 1.07e-09

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 53.38  E-value: 1.07e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 145332709    67 RGHWRISEDTQLMELVSVYGPQNWNHIAESMQGRTGKSCRLRWFNQLDP 115
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
70-111 1.56e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 52.58  E-value: 1.56e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 145332709  70 WRISEDTQLMELVSVYGPQNWNHIAESMQGRTGKSCRLRWFN 111
Cdd:cd00167    2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRN 43
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
121-164 3.19e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 51.81  E-value: 3.19e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 145332709 121 AFSDEEEERLLAAHRAFG-NKWAMIAKLFNGRTDNALKNHWHVLM 164
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
119-166 3.91e-09

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 51.84  E-value: 3.91e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 145332709   119 KRAFSDEEEERLLAAHRAFG-NKWAMIAKLFNGRTDNALKNHWHVLMAR 166
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
122-172 2.07e-07

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 47.30  E-value: 2.07e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 145332709  122 FSDEEEERLLAAHRAFGNKWAMIAKLFNGRTDNALKNHWHVLMARKMRQQS 172
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGP 51
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
115-154 4.21e-05

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 40.37  E-value: 4.21e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 145332709 115 PRINKRAFSDEEEERLLAAHRAFGNKWAMIAKLFnGRTDN 154
Cdd:cd11659    1 PSIKKTEWTREEDEKLLHLAKLLPTQWRTIAPIV-GRTAQ 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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