DNA-binding protein SATB1 isoform 1 [Homo sapiens]
CUT homeobox family transcription factor; homeobox domain-containing protein( domain architecture ID 11243836)
CUT homeobox family transcription factor regulates gene networks by controlling the expression of other transcription factors and plays an important role in cell differentiation and metabolism| homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes
List of domain hits
Name | Accession | Description | Interval | E-value | |||
ULD | pfam16534 | Ubiquitin-like oligomerization domain of SATB; ULD is an N-terminal oligomerization domain of ... |
72-170 | 5.99e-55 | |||
Ubiquitin-like oligomerization domain of SATB; ULD is an N-terminal oligomerization domain of SATB or special AT-rich sequence-binding proteins. SATBs are global chromatin organizers and regulators of gene expression that are essential for T-cell development, breast cancer tumour growth and metastasis. SATBs assemble into a tetramer via the ULD domain, and the tetramerization of SATBs are essential for recognising specific DNA sequences (such as multiple AT-rich DNA fragments). Thus, SATBs may regulate gene expression directly by binding to various promoters and upstream regions and thereby influencing promoter activity. : Pssm-ID: 465165 Cd Length: 105 Bit Score: 184.08 E-value: 5.99e-55
|
|||||||
CUTL | pfam16557 | CUT1-like DNA-binding domain of SATB; CUTL is part of the N-terminal region of SATB proteins, ... |
176-247 | 2.87e-39 | |||
CUT1-like DNA-binding domain of SATB; CUTL is part of the N-terminal region of SATB proteins, special AT-rich sequence-binding proteins that are global chromatin organizers and gene expression regulators essential for T-cell development and breast cancer tumour growth and metastasis. CUTL carries a DNA-binding region just as CUT domains do. : Pssm-ID: 435427 Cd Length: 72 Bit Score: 139.30 E-value: 2.87e-39
|
|||||||
CUT | pfam02376 | CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ... |
497-567 | 4.52e-19 | |||
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein. : Pssm-ID: 460543 Cd Length: 78 Bit Score: 81.87 E-value: 4.52e-19
|
|||||||
CUT super family | cl08348 | CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ... |
372-444 | 1.38e-18 | |||
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein. The actual alignment was detected with superfamily member pfam02376: Pssm-ID: 460543 Cd Length: 78 Bit Score: 80.71 E-value: 1.38e-18
|
|||||||
HOX | smart00389 | Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ... |
644-701 | 4.98e-09 | |||
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes : Pssm-ID: 197696 [Multi-domain] Cd Length: 57 Bit Score: 52.64 E-value: 4.98e-09
|
|||||||
Name | Accession | Description | Interval | E-value | |||
ULD | pfam16534 | Ubiquitin-like oligomerization domain of SATB; ULD is an N-terminal oligomerization domain of ... |
72-170 | 5.99e-55 | |||
Ubiquitin-like oligomerization domain of SATB; ULD is an N-terminal oligomerization domain of SATB or special AT-rich sequence-binding proteins. SATBs are global chromatin organizers and regulators of gene expression that are essential for T-cell development, breast cancer tumour growth and metastasis. SATBs assemble into a tetramer via the ULD domain, and the tetramerization of SATBs are essential for recognising specific DNA sequences (such as multiple AT-rich DNA fragments). Thus, SATBs may regulate gene expression directly by binding to various promoters and upstream regions and thereby influencing promoter activity. Pssm-ID: 465165 Cd Length: 105 Bit Score: 184.08 E-value: 5.99e-55
|
|||||||
SATB1_N | cd11585 | N-terminal domain of SATB1 and similar proteins; SATB1, the special AT-rich sequence-binding ... |
74-169 | 2.09e-50 | |||
N-terminal domain of SATB1 and similar proteins; SATB1, the special AT-rich sequence-binding protein 1, is involved in organizing chromosomal loci into distinct loops, creating a "loopscape" that has a direct bearing on gene expression. This N-terminal domain, which may be involved in various interactions with chromatin proteins, resembles a ubiquitin domain and has been shown to form tetramers, a function critical to SATB1-DNA interactions. The related Drosophila homeobox gene defective proventriculus (dve) plays a key role in the functional specification during endoderm development. Pssm-ID: 211426 Cd Length: 100 Bit Score: 171.36 E-value: 2.09e-50
|
|||||||
CUTL | pfam16557 | CUT1-like DNA-binding domain of SATB; CUTL is part of the N-terminal region of SATB proteins, ... |
176-247 | 2.87e-39 | |||
CUT1-like DNA-binding domain of SATB; CUTL is part of the N-terminal region of SATB proteins, special AT-rich sequence-binding proteins that are global chromatin organizers and gene expression regulators essential for T-cell development and breast cancer tumour growth and metastasis. CUTL carries a DNA-binding region just as CUT domains do. Pssm-ID: 435427 Cd Length: 72 Bit Score: 139.30 E-value: 2.87e-39
|
|||||||
CUT | pfam02376 | CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ... |
497-567 | 4.52e-19 | |||
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein. Pssm-ID: 460543 Cd Length: 78 Bit Score: 81.87 E-value: 4.52e-19
|
|||||||
CUT | pfam02376 | CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ... |
372-444 | 1.38e-18 | |||
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein. Pssm-ID: 460543 Cd Length: 78 Bit Score: 80.71 E-value: 1.38e-18
|
|||||||
HOX | smart00389 | Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ... |
644-701 | 4.98e-09 | |||
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes Pssm-ID: 197696 [Multi-domain] Cd Length: 57 Bit Score: 52.64 E-value: 4.98e-09
|
|||||||
homeodomain | cd00086 | Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ... |
646-703 | 7.63e-08 | |||
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. Pssm-ID: 238039 [Multi-domain] Cd Length: 59 Bit Score: 49.55 E-value: 7.63e-08
|
|||||||
Homeodomain | pfam00046 | Homeodomain; |
646-697 | 2.34e-05 | |||
Homeodomain; Pssm-ID: 459649 [Multi-domain] Cd Length: 57 Bit Score: 42.49 E-value: 2.34e-05
|
|||||||
Name | Accession | Description | Interval | E-value | |||
ULD | pfam16534 | Ubiquitin-like oligomerization domain of SATB; ULD is an N-terminal oligomerization domain of ... |
72-170 | 5.99e-55 | |||
Ubiquitin-like oligomerization domain of SATB; ULD is an N-terminal oligomerization domain of SATB or special AT-rich sequence-binding proteins. SATBs are global chromatin organizers and regulators of gene expression that are essential for T-cell development, breast cancer tumour growth and metastasis. SATBs assemble into a tetramer via the ULD domain, and the tetramerization of SATBs are essential for recognising specific DNA sequences (such as multiple AT-rich DNA fragments). Thus, SATBs may regulate gene expression directly by binding to various promoters and upstream regions and thereby influencing promoter activity. Pssm-ID: 465165 Cd Length: 105 Bit Score: 184.08 E-value: 5.99e-55
|
|||||||
SATB1_N | cd11585 | N-terminal domain of SATB1 and similar proteins; SATB1, the special AT-rich sequence-binding ... |
74-169 | 2.09e-50 | |||
N-terminal domain of SATB1 and similar proteins; SATB1, the special AT-rich sequence-binding protein 1, is involved in organizing chromosomal loci into distinct loops, creating a "loopscape" that has a direct bearing on gene expression. This N-terminal domain, which may be involved in various interactions with chromatin proteins, resembles a ubiquitin domain and has been shown to form tetramers, a function critical to SATB1-DNA interactions. The related Drosophila homeobox gene defective proventriculus (dve) plays a key role in the functional specification during endoderm development. Pssm-ID: 211426 Cd Length: 100 Bit Score: 171.36 E-value: 2.09e-50
|
|||||||
CUTL | pfam16557 | CUT1-like DNA-binding domain of SATB; CUTL is part of the N-terminal region of SATB proteins, ... |
176-247 | 2.87e-39 | |||
CUT1-like DNA-binding domain of SATB; CUTL is part of the N-terminal region of SATB proteins, special AT-rich sequence-binding proteins that are global chromatin organizers and gene expression regulators essential for T-cell development and breast cancer tumour growth and metastasis. CUTL carries a DNA-binding region just as CUT domains do. Pssm-ID: 435427 Cd Length: 72 Bit Score: 139.30 E-value: 2.87e-39
|
|||||||
CUT | pfam02376 | CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ... |
497-567 | 4.52e-19 | |||
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein. Pssm-ID: 460543 Cd Length: 78 Bit Score: 81.87 E-value: 4.52e-19
|
|||||||
CUT | pfam02376 | CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ... |
372-444 | 1.38e-18 | |||
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein. Pssm-ID: 460543 Cd Length: 78 Bit Score: 80.71 E-value: 1.38e-18
|
|||||||
HOX | smart00389 | Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ... |
644-701 | 4.98e-09 | |||
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes Pssm-ID: 197696 [Multi-domain] Cd Length: 57 Bit Score: 52.64 E-value: 4.98e-09
|
|||||||
homeodomain | cd00086 | Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ... |
646-703 | 7.63e-08 | |||
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. Pssm-ID: 238039 [Multi-domain] Cd Length: 59 Bit Score: 49.55 E-value: 7.63e-08
|
|||||||
Homeodomain | pfam00046 | Homeodomain; |
646-697 | 2.34e-05 | |||
Homeodomain; Pssm-ID: 459649 [Multi-domain] Cd Length: 57 Bit Score: 42.49 E-value: 2.34e-05
|
|||||||
Blast search parameters | ||||
|