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Conserved domains on  [gi|227430397|ref|NP_001153082|]
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leucine-rich repeat-containing protein 57 isoform a [Mus musculus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
72-267 3.69e-33

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 125.43  E-value: 3.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  72 PSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSA 151
Cdd:COG4886  106 NEELSNLT-NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 152 LKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSvKISCCPRLKVLRLEENcl 230
Cdd:COG4886  184 LKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLEtLDLSNNQLTDLP-ELGNLTNLEELDLSNN-- 260

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 227430397 231 ELSMLPQSiLSDSQICLLAVEGNLFEIKKLRELEGYD 267
Cdd:COG4886  261 QLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLL 296
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
72-267 3.69e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 125.43  E-value: 3.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  72 PSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSA 151
Cdd:COG4886  106 NEELSNLT-NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 152 LKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSvKISCCPRLKVLRLEENcl 230
Cdd:COG4886  184 LKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLEtLDLSNNQLTDLP-ELGNLTNLEELDLSNN-- 260

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 227430397 231 ELSMLPQSiLSDSQICLLAVEGNLFEIKKLRELEGYD 267
Cdd:COG4886  261 QLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLL 296
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
63-253 2.21e-16

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 78.97  E-value: 2.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  63 LKDRGLTEFPSELQKltsNLRTIDLSNNKIDSLPPLIIGKftlLKSLSLNNNKLTVLPDELCNlkKLETLSLNNNHLREL 142
Cdd:PRK15370 185 LKILGLTTIPACIPE---QITTLILDNNELKSLPENLQGN---IKTLYANSNQLTSIPATLPD--TIQEMELSINRITEL 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 143 PSTFGqlSALKTLSLSGNQLGALPPQLC-CLRHLDVVDlskNQIRSIPDTVGElQAIELNLNQNQISQLSVKISccPRLK 221
Cdd:PRK15370 257 PERLP--SALQSLDLFHNKISCLPENLPeELRYLSVYD---NSIRTLPAHLPS-GITHLNVQSNSLTALPETLP--PGLK 328

                        170       180       190
                 ....*....|....*....|....*....|..
gi 227430397 222 VLRLEENCleLSMLPQSILSDSQIclLAVEGN 253
Cdd:PRK15370 329 TLEAGENA--LTSLPASLPPELQV--LDVSKN 356
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 63-230 3.60e-14

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 69.81  E-value: 3.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  63 LKDRGLTEFpsELQKLTSNLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKLTVLpDELCNLKKLETLSLNNNHLREL 142
Cdd:cd21340    9 LNDKNITKI--DNLSLCKNLKVLYLYDNKITKIENL--EFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 143 pSTFGQLSALKTLSLSGNQLgALPPQLC-----------CLRHLDVvdlSKNQIRSIPDtVGELQAIE-LNLNQNQIS-- 208
Cdd:cd21340   84 -EGLENLTNLEELHIENQRL-PPGEKLTfdprslaalsnSLRVLNI---SGNNIDSLEP-LAPLRNLEqLDASNNQISdl 157

                        170       180
                 ....*....|....*....|...
gi 227430397 209 -QLSVKISCCPRLKVLRLEENCL 230
Cdd:cd21340  158 eELLDLLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
80-139 3.37e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 52.14  E-value: 3.37e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 227430397   80 SNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVL-PDELCNLKKLETLSLNNNHL 139
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
72-267 3.69e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 125.43  E-value: 3.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  72 PSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSA 151
Cdd:COG4886  106 NEELSNLT-NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 152 LKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSvKISCCPRLKVLRLEENcl 230
Cdd:COG4886  184 LKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLEtLDLSNNQLTDLP-ELGNLTNLEELDLSNN-- 260

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 227430397 231 ELSMLPQSiLSDSQICLLAVEGNLFEIKKLRELEGYD 267
Cdd:COG4886  261 QLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLL 296
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
63-263 3.45e-30

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 117.34  E-value: 3.45e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  63 LKDRGLTEFPSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLREL 142
Cdd:COG4886  143 LSNNQLTDLPEPLGNLT-NLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 143 PSTFGQLSALKTLSLSGNQLGALPpQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQLSVKISCCPRLKV 222
Cdd:COG4886  221 PEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 227430397 223 LRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKLREL 263
Cdd:COG4886  300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTL 340
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
63-253 2.21e-16

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 78.97  E-value: 2.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  63 LKDRGLTEFPSELQKltsNLRTIDLSNNKIDSLPPLIIGKftlLKSLSLNNNKLTVLPDELCNlkKLETLSLNNNHLREL 142
Cdd:PRK15370 185 LKILGLTTIPACIPE---QITTLILDNNELKSLPENLQGN---IKTLYANSNQLTSIPATLPD--TIQEMELSINRITEL 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 143 PSTFGqlSALKTLSLSGNQLGALPPQLC-CLRHLDVVDlskNQIRSIPDTVGElQAIELNLNQNQISQLSVKISccPRLK 221
Cdd:PRK15370 257 PERLP--SALQSLDLFHNKISCLPENLPeELRYLSVYD---NSIRTLPAHLPS-GITHLNVQSNSLTALPETLP--PGLK 328

                        170       180       190
                 ....*....|....*....|....*....|..
gi 227430397 222 VLRLEENCleLSMLPQSILSDSQIclLAVEGN 253
Cdd:PRK15370 329 TLEAGENA--LTSLPASLPPELQV--LDVSKN 356
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 80-230 3.05e-14

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 72.57  E-value: 3.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  80 SNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSTFGQLSALKTLSL 157
Cdd:PLN00113 140 PNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYL 219

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 227430397 158 SGNQL-GALPPQ---LCCLRHLDVVdlSKNQIRSIPDTVGELQAIE-LNLNQNQIS-QLSVKISCCPRLKVLRLEENCL 230
Cdd:PLN00113 220 GYNNLsGEIPYEiggLTSLNHLDLV--YNNLTGPIPSSLGNLKNLQyLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSL 296
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 63-230 3.60e-14

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 69.81  E-value: 3.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  63 LKDRGLTEFpsELQKLTSNLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKLTVLpDELCNLKKLETLSLNNNHLREL 142
Cdd:cd21340    9 LNDKNITKI--DNLSLCKNLKVLYLYDNKITKIENL--EFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 143 pSTFGQLSALKTLSLSGNQLgALPPQLC-----------CLRHLDVvdlSKNQIRSIPDtVGELQAIE-LNLNQNQIS-- 208
Cdd:cd21340   84 -EGLENLTNLEELHIENQRL-PPGEKLTfdprslaalsnSLRVLNI---SGNNIDSLEP-LAPLRNLEqLDASNNQISdl 157

                        170       180
                 ....*....|....*....|...
gi 227430397 209 -QLSVKISCCPRLKVLRLEENCL 230
Cdd:cd21340  158 eELLDLLSSWPSLRELDLTGNPV 180
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 79-198 7.71e-14

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 71.42  E-value: 7.71e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  79 TSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSTFGQLSALKTLS 156
Cdd:PLN00113 474 SKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLD 553

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 227430397 157 LSGNQL-GALPPQLCCLRHLDVVDLSKNQIR-SIPDTvGELQAI 198
Cdd:PLN00113 554 LSQNQLsGEIPKNLGNVESLVQVNISHNHLHgSLPST-GAFLAI 596
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
60-264 2.59e-13

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 69.73  E-value: 2.59e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  60 VFQLKDRGLTEFPselQKLTSNLRTIDLSNNKIDSLPPLIIGKftlLKSLSLNNNKLTVLPDELCNlkKLETLSLNNNHL 139
Cdd:PRK15370 245 EMELSINRITELP---ERLPSALQSLDLFHNKISCLPENLPEE---LRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSL 316

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 140 RELPSTFGQlsALKTLSLSGNQLGALPPQLCclRHLDVVDLSKNQIRSIPDTV-GELQaiELNLNQNQISQLSVKISCCp 218
Cdd:PRK15370 317 TALPETLPP--GLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLpPTIT--TLDVSRNALTNLPENLPAA- 389

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 227430397 219 rLKVLRLEENclELSMLPQSILS----DSQICLLAVEGNLFEIKKLRELE 264
Cdd:PRK15370 390 -LQIMQASRN--NLVRLPESLPHfrgeGPQPTRIIVEYNPFSERTIQNMQ 436
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
68-211 1.44e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 1.44e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  68 LTEFPSELQKLTsNLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKLTVLPdELCNLKKLETLSLNNNHLRELPSTFG 147
Cdd:COG4886  217 LTDLPEPLANLT-NLETLDLSNNQLTDLPEL--GNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKEL 292

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 227430397 148 QLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQLS 211
Cdd:COG4886  293 ELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLL 356
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
75-239 9.35e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.87  E-value: 9.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  75 LQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKT 154
Cdd:COG4886   21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 155 LS-----------------LSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSVKISC 216
Cdd:COG4886  101 LDlsgneelsnltnlesldLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKsLDLSNNQLTDLPEELGN 180

                        170       180
                 ....*....|....*....|...
gi 227430397 217 CPRLKVLRLEENclELSMLPQSI 239
Cdd:COG4886  181 LTNLKELDLSNN--QITDLPEPL 201
LRR_8 pfam13855
Leucine rich repeat;
80-139 3.37e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 52.14  E-value: 3.37e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 227430397   80 SNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVL-PDELCNLKKLETLSLNNNHL 139
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 70-230 7.62e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 56.39  E-value: 7.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  70 EFPSELQKLTsNLRTIDLSNNKI-DSLPPLIIGkFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSTF 146
Cdd:PLN00113 251 PIPSSLGNLK-NLQYLFLYQNKLsGPIPPSIFS-LQKLISLDLSDNSLSgEIPELVIQLQNLEILHLFSNNFTgKIPVAL 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 147 GQLSALKTLSLSGNQL-GALPPQLCCLRHLDVVDLSKNQIRS-IPDTV---GELqaIELNLNQNQI-SQLSVKISCCPRL 220
Cdd:PLN00113 329 TSLPRLQVLQLWSNKFsGEIPKNLGKHNNLTVLDLSTNNLTGeIPEGLcssGNL--FKLILFSNSLeGEIPKSLGACRSL 406

                        170
                 ....*....|
gi 227430397 221 KVLRLEENCL 230
Cdd:PLN00113 407 RRVRLQDNSF 416
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
68-263 1.77e-08

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 55.17  E-value: 1.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  68 LTEFPSelqkLTSNLRTIDLSNNKIDSLPPLIIGkftlLKSLSLNNNKLT---VLPDELCNL----KKLETLSLNNNHLR 140
Cdd:PRK15387 274 LTHLPA----LPSGLCKLWIFGNQLTSLPVLPPG----LQELSVSDNQLAslpALPSELCKLwaynNQLTSLPTLPSGLQ 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 141 ELPSTFGQLSALKTLSLS-------GNQLGALPPQLCCLRHLDVvdlSKNQIRSIPDTVGELQaiELNLNQNQISQLSVK 213
Cdd:PRK15387 346 ELSVSDNQLASLPTLPSElyklwayNNRLTSLPALPSGLKELIV---SGNRLTSLPVLPSELK--ELMVSGNRLTSLPML 420

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 227430397 214 ISCCPRLKVLRleencLELSMLPQSILSDSQICLLAVEGNLFEIKKLREL 263
Cdd:PRK15387 421 PSGLLSLSVYR-----NQLTRLPESLIHLSSETTVNLEGNPLSERTLQAL 465
LRR_8 pfam13855
Leucine rich repeat;
106-162 1.90e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.83  E-value: 1.90e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 227430397  106 LKSLSLNNNKLTVLPDE-LCNLKKLETLSLNNNHLREL-PSTFGQLSALKTLSLSGNQL 162
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
46-169 6.80e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.55  E-value: 6.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  46 SALRAHVetaqKTGVFQL--KDRGLTEFPselQKLTSNLRTIDLSNNKIDSLPPLIIGKftlLKSLSLNNNKLTVLPDEL 123
Cdd:PRK15370 296 RTLPAHL----PSGITHLnvQSNSLTALP---ETLPPGLKTLEAGENALTSLPASLPPE---LQVLDVSKNQITVLPETL 365

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 227430397 124 CnlKKLETLSLNNNHLRELPSTFGqlSALKTLSLSGNQLGALPPQL 169
Cdd:PRK15370 366 P--PTITTLDVSRNALTNLPENLP--AALQIMQASRNNLVRLPESL 407
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 75-230 7.74e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 53.31  E-value: 7.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  75 LQKLTSnlrtIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSTFGQLSAL 152
Cdd:PLN00113 283 LQKLIS----LDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNL 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 153 KTLSLSGNQL-GALPPQLCCLRHLDVVDLSKNQIRS-IPDTVGELQAIE-LNLNQNQIS-QLSVKISCCPRLKVLRLEEN 228
Cdd:PLN00113 359 TVLDLSTNNLtGEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGACRSLRrVRLQDNSFSgELPSEFTKLPLVYFLDISNN 438


                 ..
gi 227430397 229 CL 230
Cdd:PLN00113 439 NL 440
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 65-233 1.80e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.59  E-value: 1.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  65 DRGLTEFPSELQKlTSNLRTIDLSNNKI--DSLPPLI-IGKFTLLKSLSLNNNKL---------TVLPDELCNLKK--LE 130
Cdd:cd00116   67 PRGLQSLLQGLTK-GCGLQELDLSDNALgpDGCGVLEsLLRSSSLQELKLNNNGLgdrglrllaKGLKDLPPALEKlvLG 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 131 TLSLNNNHLRELPSTFGQLSALKTLSLSGNQLG-----ALPPQLCCLRHLDVVDLSKNQIRS-----IPDTVGELQAIE- 199
Cdd:cd00116  146 RNRLEGASCEALAKALRANRDLKELNLANNGIGdagirALAEGLKANCNLEVLDLNNNGLTDegasaLAETLASLKSLEv 225

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 227430397 200 LNLNQNQISQ------LSVKISCCPRLKVLRLEENCLELS 233
Cdd:cd00116  226 LNLGDNNLTDagaaalASALLSPNISLLTLSLSCNDITDD 265
PLN03150 PLN03150
hypothetical protein; Provisional
 63-147 2.86e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 51.36  E-value: 2.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  63 LKDRGLTEF-PSELQKLtSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR 140
Cdd:PLN03150 425 LDNQGLRGFiPNDISKL-RHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLS 503


                 ....*...
gi 227430397 141 -ELPSTFG 147
Cdd:PLN03150 504 gRVPAALG 511
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-230 3.02e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 51.39  E-value: 3.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  60 VFQLKDRGLT-EFPSELQKlTSNLRTIDLSNNKIDS-LPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNN 137
Cdd:PLN00113 336 VLQLWSNKFSgEIPKNLGK-HNNLTVLDLSTNNLTGeIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDN 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 138 HLR-ELPSTFGQL------------------------SALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIR-SIPDT 191
Cdd:PLN00113 415 SFSgELPSEFTKLplvyfldisnnnlqgrinsrkwdmPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSgAVPRK 494

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 227430397 192 VGELQAI-ELNLNQNQIS-QLSVKISCCPRLKVLRLEENCL 230
Cdd:PLN00113 495 LGSLSELmQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQL 535
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 65-213 3.57e-07

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 50.94  E-value: 3.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  65 DRGLTEFPSELQKLTSnLRTIDLSNNKIDSLPPLIIGKF----TLLKSLSLNNNKLTV-----LPDELCNLKKLETLSLN 135
Cdd:COG5238  222 DEGAEILAEALKGNKS-LTTLDLSNNQIGDEGVIALAEAlknnTTVETLYLSGNQIGAegaiaLAKALQGNTTLTSLDLS 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 136 NNHLRE-----LPSTFGQLSALKTLSLSGNQLG-----ALPPQLCCLRHLDVVDLSKNQIRS------IPDTVGELQAIE 199
Cdd:COG5238  301 VNRIGDegaiaLAEGLQGNKTLHTLNLAYNGIGaqgaiALAKALQENTTLHSLDLSDNQIGDegaialAKYLEGNTTLRE 380

                        170
                 ....*....|....
gi 227430397 200 LNLNQNQISQLSVK 213
Cdd:COG5238  381 LNLGKNNIGKQGAE 394
LRR_8 pfam13855
Leucine rich repeat;
128-185 6.18e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.59  E-value: 6.18e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  128 KLETLSLNNNHLREL-PSTFGQLSALKTLSLSGNQLGALPPQ-LCCLRHLDVVDLSKNQI 185
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 79-211 2.07e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.69  E-value: 2.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  79 TSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDE------------LCN-----------LKKLETLSL 134
Cdd:PLN00113  68 SSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSgPIPDDifttssslrylnLSNnnftgsiprgsIPNLETLDL 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 135 NNNHLR-ELPSTFGQLSALKTLSLSGNQL-GALPPQLCCLRHLDVVDLSKNQ-IRSIPDTVGE---LQAIELNLNQ---- 204
Cdd:PLN00113 148 SNNMLSgEIPNDIGSFSSLKVLDLGGNVLvGKIPNSLTNLTSLEFLTLASNQlVGQIPRELGQmksLKWIYLGYNNlsge 227


                 ....*....
gi 227430397 205 --NQISQLS 211
Cdd:PLN00113 228 ipYEIGGLT 236
PLN03150 PLN03150
hypothetical protein; Provisional
 85-169 2.72e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.27  E-value: 2.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  85 IDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSTFGQLSALKTLSLSGNQL 162
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSL 502


                 ....*...
gi 227430397 163 -GALPPQL 169
Cdd:PLN03150 503 sGRVPAAL 510
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 62-213 4.13e-06

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 47.48  E-value: 4.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  62 QLKDRGLTEFPSELQKLTsNLRTIDLSNNKIDSLPPLIIGK----FTLLKSLSLNNNKLT-----VLPDELCNLKKLETL 132
Cdd:COG5238  191 QIGDEGIEELAEALTQNT-TVTTLWLKRNPIGDEGAEILAEalkgNKSLTTLDLSNNQIGdegviALAEALKNNTTVETL 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 133 SLNNNHLRE-----LPSTFGQLSALKTLSLSGNQLG-----ALPPQLCCLRHLDVVDLSKNQI-----RSIPDTVGELQA 197
Cdd:COG5238  270 YLSGNQIGAegaiaLAKALQGNTTLTSLDLSVNRIGdegaiALAEGLQGNKTLHTLNLAYNGIgaqgaIALAKALQENTT 349

                        170
                 ....*....|....*..
gi 227430397 198 IE-LNLNQNQISQLSVK 213
Cdd:COG5238  350 LHsLDLSDNQIGDEGAI 366
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 70-162 1.41e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 43.30  E-value: 1.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  70 EFPSELQKlTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSTfG 147
Cdd:PLN00113 514 EIPDELSS-CKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHLHgSLPST-G 591

                         90
                 ....*....|....*
gi 227430397 148 QLSALKTLSLSGNQL 162
Cdd:PLN00113 592 AFLAINASAVAGNID 606
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 79-230 2.28e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.96  E-value: 2.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397  79 TSNLRTIDLSNNKIDSLPPLIIGKFTL-----LKSLSLNNNKLTV-----LPDELCNLKKLETLSLNNNHLRE-----LP 143
Cdd:cd00116  107 SSSLQELKLNNNGLGDRGLRLLAKGLKdlppaLEKLVLGRNRLEGasceaLAKALRANRDLKELNLANNGIGDagiraLA 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 144 STFGQLSALKTLSLSGN--------QLGALPPQLCCLRHLdvvDLSKNQIRS---------IPDTVGELQaiELNLNQNQ 206
Cdd:cd00116  187 EGLKANCNLEVLDLNNNgltdegasALAETLASLKSLEVL---NLGDNNLTDagaaalasaLLSPNISLL--TLSLSCND 261

                        170       180
                 ....*....|....*....|....*....
gi 227430397 207 ISQLSVK-----ISCCPRLKVLRLEENCL 230
Cdd:cd00116  262 ITDDGAKdlaevLAEKESLLELDLRGNKF 290
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 126-264 2.31e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.31  E-value: 2.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227430397 126 LKKLETLSLNNNHLRELPStFGQLSALKTLSLSGNQLGALpPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQN 205
Cdd:cd21340    1 LKRITHLYLNDKNITKIDN-LSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGN 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 227430397 206 QISQLSvKISCCPRLKVLRLEENCLELSML----PQSI--LSDSqICLLAVEGN----LFEIKKLRELE 264
Cdd:cd21340   79 RISVVE-GLENLTNLEELHIENQRLPPGEKltfdPRSLaaLSNS-LRVLNISGNnidsLEPLAPLRNLE 145
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 106-139 2.54e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.91  E-value: 2.54e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 227430397  106 LKSLSLNNNKLTVLPdELCNLKKLETLSLNNNHL 139
Cdd:pfam12799   3 LEVLDLSNNQITDIP-PLAKLPNLETLDLSGNNK 35
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 81-116 3.73e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.53  E-value: 3.73e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 227430397   81 NLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKL 116
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPL--AKLPNLETLDLSGNNK 35
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 127-162 5.17e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.14  E-value: 5.17e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 227430397  127 KKLETLSLNNNHLRELPStFGQLSALKTLSLSGNQL 162
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPP-LAKLPNLETLDLSGNNK 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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