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Conserved domains on  [gi|281363589|ref|NP_001163181|]
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uncharacterized protein Dmel_CG6424, isoform C [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK02224 super family cl32023
DNA double-strand break repair Rad50 ATPase;
462-626 1.81e-03

DNA double-strand break repair Rad50 ATPase;


The actual alignment was detected with superfamily member PRK02224:

Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363589 462 DRVKAINRRVTVLKKKLVQLE---ESLEQRLGYRpSQAERLNDKymKNALAELSKLRKERHELKTDPIAALGLKVgsggg 538
Cdd:PRK02224 572 EEVAELNSKLAELKERIESLErirTLLAAIADAE-DEIERLREK--REALAELNDERRERLAEKRERKRELEAEF----- 643
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363589 539 AGIGGQEVAKKLERMKATLAEIEQNLNEKR---------VNGHRSEqLEDLNAdqLVQEKSAVQHGLLYFESLYghpitk 609
Cdd:PRK02224 644 DEARIEEAREDKERAEEYLEQVEEKLDELReerddlqaeIGAVENE-LEELEE--LRERREALENRVEALEALY------ 714
                        170
                 ....*....|....*..
gi 281363589 610 eerDAARPLYDRYRQLK 626
Cdd:PRK02224 715 ---DEAEELESMYGDLR 728
 
Name Accession Description Interval E-value
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
462-626 1.81e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363589 462 DRVKAINRRVTVLKKKLVQLE---ESLEQRLGYRpSQAERLNDKymKNALAELSKLRKERHELKTDPIAALGLKVgsggg 538
Cdd:PRK02224 572 EEVAELNSKLAELKERIESLErirTLLAAIADAE-DEIERLREK--REALAELNDERRERLAEKRERKRELEAEF----- 643
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363589 539 AGIGGQEVAKKLERMKATLAEIEQNLNEKR---------VNGHRSEqLEDLNAdqLVQEKSAVQHGLLYFESLYghpitk 609
Cdd:PRK02224 644 DEARIEEAREDKERAEEYLEQVEEKLDELReerddlqaeIGAVENE-LEELEE--LRERREALENRVEALEALY------ 714
                        170
                 ....*....|....*..
gi 281363589 610 eerDAARPLYDRYRQLK 626
Cdd:PRK02224 715 ---DEAEELESMYGDLR 728
 
Name Accession Description Interval E-value
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
462-626 1.81e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363589 462 DRVKAINRRVTVLKKKLVQLE---ESLEQRLGYRpSQAERLNDKymKNALAELSKLRKERHELKTDPIAALGLKVgsggg 538
Cdd:PRK02224 572 EEVAELNSKLAELKERIESLErirTLLAAIADAE-DEIERLREK--REALAELNDERRERLAEKRERKRELEAEF----- 643
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281363589 539 AGIGGQEVAKKLERMKATLAEIEQNLNEKR---------VNGHRSEqLEDLNAdqLVQEKSAVQHGLLYFESLYghpitk 609
Cdd:PRK02224 644 DEARIEEAREDKERAEEYLEQVEEKLDELReerddlqaeIGAVENE-LEELEE--LRERREALENRVEALEALY------ 714
                        170
                 ....*....|....*..
gi 281363589 610 eerDAARPLYDRYRQLK 626
Cdd:PRK02224 715 ---DEAEELESMYGDLR 728
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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