NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|311771690|ref|NP_001185720|]
View 

adenylate kinase isoenzyme 1 isoform 2 [Mus musculus]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11492279)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 6-193 9.02e-128

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


:

Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 357.20  E-value: 9.02e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690    6 KKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVD 85
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   86 SSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYD 165
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
gi 311771690  166 KRGIVRKVNAEGTVDTVFSEVCTYLDSL 193
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
 
Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 6-193 9.02e-128

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 357.20  E-value: 9.02e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690    6 KKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVD 85
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   86 SSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYD 165
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
gi 311771690  166 KRGIVRKVNAEGTVDTVFSEVCTYLDSL 193
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 10-182 7.87e-75

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 223.27  E-value: 7.87e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  10 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDSSNG 89
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKER-LKKPDCKKG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  90 FLIDGYPREVKQGEEFEQKI---GQPTLLLYVDAGAETMTQRLLKRGET-------------------SGRVDDNEETIK 147
Cdd:cd01428   80 FILDGFPRTVDQAEALDELLdegIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 311771690 148 KRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTV 182
Cdd:cd01428  160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
13-167 7.91e-70

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 210.24  E-value: 7.91e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   13 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMlAKVDSSNGFLI 92
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERL-EQNDCKNGFLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   93 DGYPREVKQGEEFEQKIG---QPTLLLYVDAGAETMTQRLLKRGET---------------------------SGRVDDN 142
Cdd:pfam00406  80 DGFPRTVPQAEALEELLErgiKLDYVIEFDVPDEVLVERLTGRRIHpnsgrsyhlefnppkvpgkddvtgeplVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
gi 311771690  143 EETIKKRLETYYNATEPVISFYDKR 167
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 9-190 1.29e-66

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 203.05  E-value: 1.29e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDSSN 88
Cdd:COG0563    2 RIILL-GPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKER-LAQPDCAN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  89 GFLIDGYPREVKQGEEFE---QKIGQP-TLLLYVDAGAETMTQRLLKR---------------------------GETSG 137
Cdd:COG0563   80 GFILDGFPRTVAQAEALDellAELGIKlDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 311771690 138 RVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYL 190
Cdd:COG0563  160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk PRK00279
adenylate kinase; Reviewed
 9-193 3.68e-65

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 199.61  E-value: 3.68e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDSSN 88
Cdd:PRK00279   2 RLILL-GPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKER-LAQPDCKN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  89 GFLIDGYPREVKQGEEFE---QKIGQP-TLLLYVDAGAETMTQRLLKR---------------------------GETSG 137
Cdd:PRK00279  80 GFLLDGFPRTIPQAEALDemlKELGIKlDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 311771690 138 RVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLDSL 193
Cdd:PRK00279 160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
 
Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 6-193 9.02e-128

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 357.20  E-value: 9.02e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690    6 KKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVD 85
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   86 SSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYD 165
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
gi 311771690  166 KRGIVRKVNAEGTVDTVFSEVCTYLDSL 193
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 10-182 7.87e-75

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 223.27  E-value: 7.87e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  10 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDSSNG 89
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKER-LKKPDCKKG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  90 FLIDGYPREVKQGEEFEQKI---GQPTLLLYVDAGAETMTQRLLKRGET-------------------SGRVDDNEETIK 147
Cdd:cd01428   80 FILDGFPRTVDQAEALDELLdegIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 311771690 148 KRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTV 182
Cdd:cd01428  160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
13-167 7.91e-70

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 210.24  E-value: 7.91e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   13 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMlAKVDSSNGFLI 92
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERL-EQNDCKNGFLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   93 DGYPREVKQGEEFEQKIG---QPTLLLYVDAGAETMTQRLLKRGET---------------------------SGRVDDN 142
Cdd:pfam00406  80 DGFPRTVPQAEALEELLErgiKLDYVIEFDVPDEVLVERLTGRRIHpnsgrsyhlefnppkvpgkddvtgeplVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
gi 311771690  143 EETIKKRLETYYNATEPVISFYDKR 167
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 10-186 3.82e-69

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 208.76  E-value: 3.82e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   10 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVS-SGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKvDSSN 88
Cdd:TIGR01359   1 VVFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKrEGSENGSLIESYIKEGKIVPSEVTVELLKKAIQED-GSSK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   89 GFLIDGYPREVKQGEEFEQKIGQ---PTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYD 165
Cdd:TIGR01359  80 KFLIDGFPRNEENLEAWEKLMDNkvnFKFVLFFDCPEETMIKRLLKRGQTSGRVDDNIETLKKRFRTYNEETLPIIEHFE 159

                         170       180
                  ....*....|....*....|.
gi 311771690  166 KRGIVRKVNAEGTVDTVFSEV 186
Cdd:TIGR01359 160 NKGKVKEINAEGSVEEVFEDV 180
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 9-190 1.29e-66

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 203.05  E-value: 1.29e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDSSN 88
Cdd:COG0563    2 RIILL-GPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKER-LAQPDCAN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  89 GFLIDGYPREVKQGEEFE---QKIGQP-TLLLYVDAGAETMTQRLLKR---------------------------GETSG 137
Cdd:COG0563   80 GFILDGFPRTVAQAEALDellAELGIKlDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 311771690 138 RVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYL 190
Cdd:COG0563  160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk PRK00279
adenylate kinase; Reviewed
 9-193 3.68e-65

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 199.61  E-value: 3.68e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDSSN 88
Cdd:PRK00279   2 RLILL-GPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKER-LAQPDCKN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  89 GFLIDGYPREVKQGEEFE---QKIGQP-TLLLYVDAGAETMTQRLLKR---------------------------GETSG 137
Cdd:PRK00279  80 GFLLDGFPRTIPQAEALDemlKELGIKlDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 311771690 138 RVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLDSL 193
Cdd:PRK00279 160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 9-191 3.04e-55

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 173.96  E-value: 3.04e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690    9 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSN 88
Cdd:TIGR01351   1 RLVLL-GPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   89 GFLIDGYPREVKQGEEFEQKI-GQPTLLLYVDAGAETMTQRLLKRG--ETSGRV-------------------------D 140
Cdd:TIGR01351  80 GFILDGFPRTLSQAEALDALLeEPIDAVIELDVPDEELVERLSGRRicPSCGRVyhlkfnppkvpgcddctgellvqreD 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 311771690  141 DNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLD 191
Cdd:TIGR01351 160 DTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
PLN02200 PLN02200
adenylate kinase family protein
 10-186 2.98e-52

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 167.38  E-value: 2.98e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  10 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMlaKVDSSNG 89
Cdd:PLN02200  45 ITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEM--ESSDNNK 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  90 FLIDGYPREVKQGEEFEQKIG-QPTLLLYVDAGAETMTQRLLKRGEtsGRVDDNEETIKKRLETYYNATEPVISFYDKRG 168
Cdd:PLN02200 123 FLIDGFPRTEENRIAFERIIGaEPNVVLFFDCPEEEMVKRVLNRNQ--GRVDDNIDTIKKRLKVFNALNLPVIDYYSKKG 200

                        170
                 ....*....|....*...
gi 311771690 169 IVRKVNAEGTVDTVFSEV 186
Cdd:PLN02200 201 KLYTINAVGTVDEIFEQV 218
PRK14531 PRK14531
adenylate kinase; Provisional
 7-191 4.65e-49

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 157.67  E-value: 4.65e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   7 KAKIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMlaKVDS 86
Cdd:PRK14531   2 KQRLLFL-GPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQL--KALN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  87 SNGFLIDGYPREVKQGEEFE---QKIGQP---TLLLYVDagAETMTQRLLKRgetsGRVDDNEETIKKRLETYYNATEPV 160
Cdd:PRK14531  79 SGGWLLDGFPRTVAQAEALEpllEELKQPieaVVLLELD--DAVLIERLLAR----GRADDNEAVIRNRLEVYREKTAPL 152

                        170       180       190
                 ....*....|....*....|....*....|.
gi 311771690 161 ISFYDKRGIVRKVNAEGTVDTVFSEVCTYLD 191
Cdd:PRK14531 153 IDHYRQRGLLQSVEAQGSIEAITERIEKVLA 183
PRK14527 PRK14527
adenylate kinase; Provisional
 7-186 9.93e-47

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 151.87  E-value: 9.93e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   7 KAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDS 86
Cdd:PRK14527   5 KNKVVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDE-LAGMEP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  87 SNgFLIDGYPREVKQGEEFE---QKIGQPTL-LLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVIS 162
Cdd:PRK14527  84 VR-VIFDGFPRTLAQAEALDrllEELGARLLaVVLLEVPDEELIRRIVERARQEGRSDDNEETVRRRQQVYREQTQPLVD 162

                        170       180
                 ....*....|....*....|....
gi 311771690 163 FYDKRGIVRKVNAEGTVDTVFSEV 186
Cdd:PRK14527 163 YYEARGHLKRVDGLGTPDEVYARI 186
PRK14532 PRK14532
adenylate kinase; Provisional
 10-186 1.09e-44

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 146.51  E-value: 1.09e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  10 IIFvvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDaMLAKVDSSNG 89
Cdd:PRK14532   4 ILF--GPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEE-RLPEAEAAGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  90 FLIDGYPREVKQGEEFEQ---KIGQP---TLLLYVDagAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISF 163
Cdd:PRK14532  81 AIFDGFPRTVAQAEALDKmlaSRGQKidvVIRLKVD--DEALIERIVKRFEEQGRPDDNPEVFVTRLDAYNAQTAPLLPY 158

                        170       180
                 ....*....|....*....|...
gi 311771690 164 YDKRGIVRKVNAEGTVDTVFSEV 186
Cdd:PRK14532 159 YAGQGKLTEVDGMGSIEAVAASI 181
adk PRK02496
adenylate kinase; Provisional
 8-186 9.56e-44

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 144.12  E-value: 9.56e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   8 AKIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDaMLAKVDSS 87
Cdd:PRK02496   2 TRLIFL-GPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQE-RLQQPDAA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  88 NGFLIDGYPREVKQG---EEFEQKIGQP-TLLLYVDAGAETMTQRLLKRgetsGRVDDNEETIKKRLETYYNATEPVISF 163
Cdd:PRK02496  80 NGWILDGFPRKVTQAaflDELLQEIGQSgERVVNLDVPDDVVVERLLAR----GRKDDTEEVIRRRLEVYREQTAPLIDY 155

                        170       180
                 ....*....|....*....|...
gi 311771690 164 YDKRGIVRKVNAEGTVDTVFSEV 186
Cdd:PRK02496 156 YRDRQKLLTIDGNQSVEAVTTEL 178
PRK14528 PRK14528
adenylate kinase; Provisional
 9-186 3.52e-41

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 137.45  E-value: 3.52e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDaMLAKVDSSN 88
Cdd:PRK14528   3 NIIFM-GPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKD-RIREADCKN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  89 GFLIDGYPREVKQGEEFEQKIGQPTL----LLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFY 164
Cdd:PRK14528  81 GFLLDGFPRTVEQADALDALLKNEGKsidkAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYNKKTLPLLDFY 160

                        170       180
                 ....*....|....*....|..
gi 311771690 165 DKRGIVRKVNAEGTVDTVFSEV 186
Cdd:PRK14528 161 AAQKKLSQVNGVGSLEEVTSLI 182
AAA_17 pfam13207
AAA domain;
14-147 4.53e-41

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 135.44  E-value: 4.53e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   14 VGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSerGKKLSAIMEKGELVPLDTVLDMLRDAmLAKVDSSNGFLID 93
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAER-IAEEAGEGGVIVD 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   94 GYPREVKQGEEFE------QKIGQPTLLLYVDAGAETMTQRLLKRgETSGRVDDNEETIK 147
Cdd:pfam13207  78 GHPRIKTPAGYLPglpvevLRELKPDAIILLEADPEEILERRLKD-RTRGRDDDSEEEIR 136
PRK14530 PRK14530
adenylate kinase; Provisional
 11-192 7.39e-36

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 124.90  E-value: 7.39e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  11 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRA---------EVSSGSERgkklsAIMEKGELVPlDTVLDMLRDAML 81
Cdd:PRK14530   6 ILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRAnkqmdisdmDTEYDTPG-----EYMDAGELVP-DAVVNEIVEEAL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  82 akvDSSNGFLIDGYPREVKQGEEFEQkIGQPTLLLYVDAGAETMTQRLLKR---------------------------GE 134
Cdd:PRK14530  80 ---SDADGFVLDGYPRNLEQAEYLES-ITDLDVVLYLDVSEEELVDRLTGRrvcpdcganyhvefnqpeeegvcdecgGE 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 311771690 135 TSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLDS 192
Cdd:PRK14530 156 LIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAIDD 213
PLN02842 PLN02842
nucleotide kinase
 13-191 1.21e-35

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 130.37  E-value: 1.21e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  13 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLI 92
Cdd:PLN02842   2 ISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDAKEKGWLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  93 DGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKR-------------------GETSGRV----DDNEETIKKR 149
Cdd:PLN02842  82 DGYPRSFAQAQSLEKLKIRPDIFILLDVPDEILIDRCVGRrldpvtgkiyhiknfppesEEIKARLitrpDDTEEKVKAR 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 311771690 150 LETYYNATEPVISFYDKrgIVRKVNAEGTVDTVFSEVCTYLD 191
Cdd:PLN02842 162 LQIYKKNAEAILSTYSD--IMVKIDGNRPKEVVFEEISSLLS 201
PRK13808 PRK13808
adenylate kinase; Provisional
 11-193 3.34e-33

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 120.76  E-value: 3.34e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  11 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDaMLAKVDSSNGF 90
Cdd:PRK13808   3 LILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISD-RIEQPDAANGF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  91 LIDGYPREVKQGEEFEQKIGQPTLL------LYVDAGA-----ETMTQRLLKRGETSgRVDDNEETIKKRLETYYNATEP 159
Cdd:PRK13808  82 ILDGFPRTVPQAEALDALLKDKQLKldavveLRVNEGAllarvETRVAEMRARGEEV-RADDTPEVLAKRLASYRAQTEP 160

                        170       180       190
                 ....*....|....*....|....*....|....
gi 311771690 160 VISFYDKRGIVRKVNAEGTVDTVFSEVCTYLDSL 193
Cdd:PRK13808 161 LVHYYSEKRKLLTVDGMMTIDEVTREIGRVLAAV 194
PLN02674 PLN02674
adenylate kinase
 6-186 4.25e-31

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 113.44  E-value: 4.25e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   6 KKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMlAKVD 85
Cdd:PLN02674  29 KPDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAM-KKPS 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  86 SSNGFLIDGYPREVKQGEEFEQKIGQ------PTLLLYVDAG--AETMTQRLLKrgETSGRV------------------ 139
Cdd:PLN02674 108 CQKGFILDGFPRTVVQAQKLDEMLAKqgakidKVLNFAIDDAilEERITGRWIH--PSSGRTyhtkfappkvpgvddvtg 185

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 311771690 140 -------DDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEV 186
Cdd:PLN02674 186 epliqrkDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEV 239
PLN02459 PLN02459
probable adenylate kinase
 2-168 3.37e-26

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 100.69  E-value: 3.37e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   2 EEKLKKAKIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAML 81
Cdd:PLN02459  24 LAKGRNVNWVFL-GCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  82 AKVD-SSNGFLIDGYPREVKQGEEFEqKIGQPTLLLYVDAGAETMTQRLLKR---GETSG-------------------- 137
Cdd:PLN02459 103 AGEEeGESGFILDGFPRTVRQAEILE-GVTDIDLVVNLKLREEVLVEKCLGRricSECGKnfnvadidlkgedgrpgivm 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 311771690 138 ---------------RVDDNEETIKKRLETYYNATEPVISFYDKRG 168
Cdd:PLN02459 182 ppllpppecasklitRADDTEEVVKARLRVYKEESQPVEDFYRKRG 227
PRK14526 PRK14526
adenylate kinase; Provisional
 9-182 1.91e-24

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 94.92  E-value: 1.91e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAkVDSSN 88
Cdd:PRK14526   2 KLVFL-GPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINT-IKNND 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  89 GFLIDGYPREVKQGEEFEQKIGQPTLLLYVdAGAETMTQRLLKR---------------------------GETSGRVDD 141
Cdd:PRK14526  80 NFILDGFPRNINQAKALDKFLPNIKIINFL-IDEELLIKRLSGRrickscnnifniytlptkekgicdvckGDLYQRKDD 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 311771690 142 NEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTV 182
Cdd:PRK14526 159 KEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEV 199
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 4-169 5.33e-23

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 91.78  E-value: 5.33e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   4 KLKKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMlAK 83
Cdd:PTZ00088   2 KLKGPLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEI-AK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  84 V--DSSNGFLIDGYPREVKQGEEFeQKIGQPTLLLYVDAGAETMTQRLLKR----------------------------G 133
Cdd:PTZ00088  81 VtdDCFKGFILDGFPRNLKQCKEL-GKITNIDLFVNIYLPRNILIKKLLGRricntcnrnfniahirsdpydmppilppA 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 311771690 134 ETSG---------RVDDNEETIKKRLETYYNATEPVISFYDKRGI 169
Cdd:PTZ00088 160 DCEGckgnpklqkRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
PRK14529 PRK14529
adenylate kinase; Provisional
 11-157 8.01e-20

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 83.23  E-value: 8.01e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  11 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMlaKVDSSNGF 90
Cdd:PRK14529   3 ILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETL--KQDGKNGW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  91 LIDGYPREVKQGEEFEQKIGQPTLLL-YV--------DAGAETMTQRLLKR------------------------GETSG 137
Cdd:PRK14529  81 LLDGFPRNKVQAEKLWEALQKEGMKLdYVieillpreVAKNRIMGRRLCKNdnnhpnnifidaikpdgdvcrvcgGELST 160

                        170       180
                 ....*....|....*....|.
gi 311771690 138 RVDD-NEETIKKRLETYYNAT 157
Cdd:PRK14529 161 RADDqDEEAINKRHDIYYDTE 181
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 11-153 2.64e-08

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 50.77  E-value: 2.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   11 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAImekGELVPlDTVLDMLRDAMLAKVDssngF 90
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDERKRLFGEGRPSISYYTDA---TDRTY-ERLHELARIALRAGRP----V 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 311771690   91 LIDG---YPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSG-RVDDNEETIKKRLETY 153
Cdd:pfam13671  74 ILDAtnlRRDERARLLALAREYGVPVRIVVFEAPEEVLRERLAARARAGGdPSDVPEEVLDRQKARF 140
TMPK cd01672
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the ...
 9-192 5.94e-08

Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step in either de novo or salvage biosynthesis of thymidine triphosphate (TTP).


Pssm-ID: 238835  Cd Length: 200  Bit Score: 50.73  E-value: 5.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVVGGPGSGKGTQCEKIVQ---KYGYTHLSTGDLlraevsSGSERGKKLSAIMEKGELVPLDTVLDML-----RDAM 80
Cdd:cd01672    1 MFIVFEGIDGAGKTTLIELLAErleARGYEVVLTREP------GGTPIGEAIRELLLDPEDEKMDPRAELLlfaadRAQH 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  81 LAKV-----------------DSS---NGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVD 140
Cdd:cd01672   75 VEEVikpalargkivlsdrfvDSSlayQGAGRGLGEALIEALNDLATGGLKPDLTILLDIDPEVGLARIEARGRDDRDEQ 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 311771690 141 DNEETIKKRLETYYNatepVISFYDKRGIVrkVNAEGTVDTVFSEVCTYLDS 192
Cdd:cd01672  155 EGLEFHERVREGYLE----LAAQEPERIIV--IDASQPLEEVLAEILKAILE 200
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
10-182 2.20e-07

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 48.37  E-value: 2.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  10 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTgDLLRAEVssgseRGKKLSAIMEKGELVPL--DTVLDMLRDAMLAKVDSs 87
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRS-DVVRKRL-----FGAGLAPLERSPEATARtyARLLALARELLAAGRSV- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  88 ngfLIDG---YPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYynatEPVISFY 164
Cdd:COG0645   74 ---ILDAtflRRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEARNAEGGDSDATWEVLERQLAFE----EPLTEDE 146

                        170
                 ....*....|....*...
gi 311771690 165 DKRGIVRKVNAEGTVDTV 182
Cdd:COG0645  147 GFLLVVDTSGLEEALAAL 164
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
9-149 4.20e-06

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 45.32  E-value: 4.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   9 KIIFVVGGPGSGKGtQCEKIVQKYGYTHLSTGDLLRAEVssgSERGKKLS-------AIMEKGELVPlDTV----LDMLR 77
Cdd:PRK01184   2 KIIGVVGMPGSGKG-EFSKIAREMGIPVVVMGDVIREEV---KKRGLEPTdenigkvAIDLRKELGM-DAVakrtVPKIR 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 311771690  78 DAmlakvdSSNGFLIDGYpREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRgetsGRVDDNE--ETIKKR 149
Cdd:PRK01184  77 EK------GDEVVVIDGV-RGDAEVEYFRKEFPEDFILIAIHAPPEVRFERLKKR----GRSDDPKswEELEER 139
PRK04182 PRK04182
cytidylate kinase; Provisional
 10-190 6.97e-06

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 44.41  E-value: 6.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  10 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLR--AEvssgsERGKKLSAIMEKGELVP-LDTVLD-MLRDAMLAK-- 83
Cdd:PRK04182   2 IITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRelAK-----ERGMSLEEFNKYAEEDPeIDKEIDrRQLEIAEKEdn 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690  84 --VDSS-NGFLIDGYprevkqgeefeqkigqPTLLLYVDAGAETMTQRLLKRGETSgrVDDN-EETI------KKRLETY 153
Cdd:PRK04182  77 vvLEGRlAGWMAKDY----------------ADLKIWLKAPLEVRAERIAEREGIS--VEEAlEETIereeseAKRYKEY 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 311771690 154 YNatepvI-----SFYDkrgIV---RKVNAEGTVDTVFSEVCTYL 190
Cdd:PRK04182 139 YG-----IdiddlSIYD---LVintSRWDPEGVFDIILTAIDKLL 175
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 10-53 2.88e-05

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 42.09  E-value: 2.88e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 311771690  10 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSER 53
Cdd:cd02020    1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEEVGKLASE 44
Nitrogenase_VnfN_like cd01971
Nitrogenase_vnfN_like: VnfN subunit of the VnfEN complex-like. This group in addition to VnfN ...
 102-173 1.13e-03

Nitrogenase_vnfN_like: VnfN subunit of the VnfEN complex-like. This group in addition to VnfN contains a subset of the beta subunit of the nitrogenase MoFe protein and NifN-like proteins. The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia. NifEN participates in the synthesis of the iron-molybdenum cofactor (FeMoco) of MoFe protein of the molybdenum(Mo)-nitrogenase. NifB-co (an iron and sulfur containing precursor of the FeMoco) from NifB is transferred to NifEN where it is further processed to FeMoco. VnfEN may similarly be a scaffolding protien for the iron-vanadium cofactor (FeVco) of the vanadium-dependent (V)-nitrogenase. NifE and NifN are essential for the Mo-nitrogenase, VnfE and VnfN are not essential for the V-nitrogenase. NifE and NifN can substitute when the vnfEN genes are inactivated.


Pssm-ID: 238931 [Multi-domain]  Cd Length: 427  Bit Score: 38.94  E-value: 1.13e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 311771690 102 GEEFEQKIGQPTLLL-YVDAGAETMTQRLLKRGETSGRVDDNEET-IKKRLETYYNATEPVISFYDKRGIVRKV 173
Cdd:cd01971  223 AQHLEEKYGQPYIHSpTLPIGAKATAEFLRQVAKFAGIEKAKVEAfIKAEEKRYYHYLERFSDFMARWGLPRRF 296
AAA_18 pfam13238
AAA domain;
11-144 4.44e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 35.87  E-value: 4.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311771690   11 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGF 90
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPETRESKRLDEDKLDRLLDLLEENAALEEGGNLIIDGH 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 311771690   91 LIDGYPREVKQGEEFeqkigqptlllYVDAGAETMTQRLLKRGETSGRVDDNEE 144
Cdd:pfam13238  81 LAELEPERAKDLVGI-----------VLRASPEELLERLEKRGYEEAKIKENEE 123
PRK09518 PRK09518
bifunctional cytidylate kinase/GTPase Der; Reviewed
 10-59 8.45e-03

bifunctional cytidylate kinase/GTPase Der; Reviewed


Pssm-ID: 236546 [Multi-domain]  Cd Length: 712  Bit Score: 36.31  E-value: 8.45e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 311771690  10 IIFVVGGP-GSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSA 59
Cdd:PRK09518   2 IIVAIDGPaGVGKSSVSRALAQYLGYAYLDTGAMYRACAWWCLKQGIDLDA 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH