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Conserved domains on  [gi|320542444|ref|NP_001189181|]
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uncharacterized protein Dmel_CG42675, isoform F [Drosophila melanogaster]

Protein Classification

C2HC-type zinc finger protein( domain architecture ID 10621545)

C2HC-type zinc finger protein similar to Homo sapiens zinc finger protein 474 (ZNF474), a testis-specific zinc finger protein

CATH:  4.10.320.30
Gene Ontology:  GO:0008270
PubMed:  1280325|17210253|12665246
SCOP:  4003606

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 227-247 2.08e-07

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


:

Pssm-ID: 464037  Cd Length: 25  Bit Score: 46.42  E-value: 2.08e-07
                          10        20
                  ....*....|....*....|.
gi 320542444  227 CRYCGRHFNTDRLAKHEEVCQ 247
Cdd:pfam13913   5 CPICGRTFNPDRLAKHEKICK 25
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 343-366 2.01e-05

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


:

Pssm-ID: 464037  Cd Length: 25  Bit Score: 41.02  E-value: 2.01e-05
                          10        20
                  ....*....|....*....|....
gi 320542444  343 DYVQCPHCGRRFNEQAAERHIPKC 366
Cdd:pfam13913   1 ELVPCPICGRTFNPDRLAKHEKIC 24
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 71-225 7.26e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 7.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542444   71 RRRGAGIDRSNPLKPIGTLPSPPAQTKSRPQPPMQR----------LVKGVADLTMRDAPnAPG-----RRITSDSNNNK 135
Cdd:PHA03247 2597 RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSpaanepdphpPPTVPPPERPRDDP-APGrvsrpRRARRLGRAAQ 2675

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542444  136 -FATPRGTLNRNLKPVVTRKT----PPAQEttlhqRSPAPQRSPKIQATQRVSGGTGAAPTAGRLSPPFVRRAEPKSPVK 210
Cdd:PHA03247 2676 aSSPPQRPRRRAARPTVGSLTsladPPPPP-----PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                         170
                  ....*....|....*
gi 320542444  211 KVNmDTTTAIPEGTA 225
Cdd:PHA03247 2751 PGG-PARPARPPTTA 2764
 
Name Accession Description Interval E-value
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 227-247 2.08e-07

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 46.42  E-value: 2.08e-07
                          10        20
                  ....*....|....*....|.
gi 320542444  227 CRYCGRHFNTDRLAKHEEVCQ 247
Cdd:pfam13913   5 CPICGRTFNPDRLAKHEKICK 25
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 343-366 2.01e-05

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 41.02  E-value: 2.01e-05
                          10        20
                  ....*....|....*....|....
gi 320542444  343 DYVQCPHCGRRFNEQAAERHIPKC 366
Cdd:pfam13913   1 ELVPCPICGRTFNPDRLAKHEKIC 24
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-225 7.26e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 7.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542444   71 RRRGAGIDRSNPLKPIGTLPSPPAQTKSRPQPPMQR----------LVKGVADLTMRDAPnAPG-----RRITSDSNNNK 135
Cdd:PHA03247 2597 RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSpaanepdphpPPTVPPPERPRDDP-APGrvsrpRRARRLGRAAQ 2675

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542444  136 -FATPRGTLNRNLKPVVTRKT----PPAQEttlhqRSPAPQRSPKIQATQRVSGGTGAAPTAGRLSPPFVRRAEPKSPVK 210
Cdd:PHA03247 2676 aSSPPQRPRRRAARPTVGSLTsladPPPPP-----PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                         170
                  ....*....|....*
gi 320542444  211 KVNmDTTTAIPEGTA 225
Cdd:PHA03247 2751 PGG-PARPARPPTTA 2764
 
Name Accession Description Interval E-value
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 227-247 2.08e-07

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 46.42  E-value: 2.08e-07
                          10        20
                  ....*....|....*....|.
gi 320542444  227 CRYCGRHFNTDRLAKHEEVCQ 247
Cdd:pfam13913   5 CPICGRTFNPDRLAKHEKICK 25
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 343-366 2.01e-05

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 41.02  E-value: 2.01e-05
                          10        20
                  ....*....|....*....|....
gi 320542444  343 DYVQCPHCGRRFNEQAAERHIPKC 366
Cdd:pfam13913   1 ELVPCPICGRTFNPDRLAKHEKIC 24
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-225 7.26e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 7.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542444   71 RRRGAGIDRSNPLKPIGTLPSPPAQTKSRPQPPMQR----------LVKGVADLTMRDAPnAPG-----RRITSDSNNNK 135
Cdd:PHA03247 2597 RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSpaanepdphpPPTVPPPERPRDDP-APGrvsrpRRARRLGRAAQ 2675

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542444  136 -FATPRGTLNRNLKPVVTRKT----PPAQEttlhqRSPAPQRSPKIQATQRVSGGTGAAPTAGRLSPPFVRRAEPKSPVK 210
Cdd:PHA03247 2676 aSSPPQRPRRRAARPTVGSLTsladPPPPP-----PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                         170
                  ....*....|....*
gi 320542444  211 KVNmDTTTAIPEGTA 225
Cdd:PHA03247 2751 PGG-PARPARPPTTA 2764
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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