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heat shock protein 81-2 [Arabidopsis thaliana]
Protein Classification
HSP90 family protein ( domain architecture ID 1903338 )
HSP90 (heat shock protein 90) family protein functions as a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in cell cycle control and signal transduction
List of domain hits
Name
Accession
Description
Interval
E-value
HSP90 super family
cl46693 Hsp90 protein;
5-728
0e+00
Hsp90 protein;
PTZ00272 :Pssm-ID: 481033
Cd Length: 701
Bit Score: 954.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 5 ETFAFQAEINQL L SLIINTFYSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl A L DKIR FE SLTD K S 84
Cdd:PTZ00272 3 ETFAFQAEINQL M SLIINTFYSNKEIFLRELISN A SD ----------------------------- A C DKIR YQ SLTD P S 53
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 85 K L DGQ P E L F I HII PDK T N N TLT II D S GIGMTKADLVNNLGTIARSGTK E FMEAL A AG A D V SMIGQFGVGFYSAYLVAD K V 164
Cdd:PTZ00272 54 V L GES P R L C I RVV PDK E N K TLT VE D N GIGMTKADLVNNLGTIARSGTK A FMEAL E AG G D M SMIGQFGVGFYSAYLVAD R V 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 165 V VT T K H N D DE Q YVWES Q AGG S FT V T r D T SGETLG RGT KMV L Y LKEDQ L EYLE E RRLK D L V KKHSEFI S Y P I S L WI EKT -- 242
Cdd:PTZ00272 134 T VT S K N N S DE S YVWES S AGG T FT I T - S T PESDMK RGT RIT L H LKEDQ M EYLE P RRLK E L I KKHSEFI G Y D I E L MV EKT te 212
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 243 -- IEK E ISD D EEEEEKKD EE G KVEEV D E EK E KEE KK K KK I KEV SH E WDLV NK Q KP I W M R K P EEIN KEEYAAFYK SL SNDW 320
Cdd:PTZ00272 213 ke VTD E DEE D TKKADEDG EE P KVEEV K E GD E GKK KK T KK V KEV TK E YEVQ NK H KP L W T R D P KDVT KEEYAAFYK AI SNDW 292
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 321 E EHL A V KHFSVEGQLEF KA I L FVPKRAPFD L F DTK KK P NNIKLYVRRVFIMDNCED II P EY LGFVKG I VDSEDLPLNISR 400
Cdd:PTZ00272 293 E DPA A T KHFSVEGQLEF RS I M FVPKRAPFD M F EPN KK R NNIKLYVRRVFIMDNCED LC P DW LGFVKG V VDSEDLPLNISR 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 401 E T LQQNKILKVIRKN L VKKCLE L F F E I AENKEDY NK FYE A F S KN L KLGIHED SQ NR T K IA ELLR YH ST K SG D E L T S LKDY 480
Cdd:PTZ00272 373 E N LQQNKILKVIRKN I VKKCLE M F D E V AENKEDY KQ FYE Q F G KN I KLGIHED TA NR K K LM ELLR FY ST E SG E E M T T LKDY 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 481 VTRMK E GQ ND I F YITG E SKK AV E N SPF L E KLKKK G I EVL Y M VDA IDEY AIG Q L K E FE G KK LVSA TKEG LKLD E T E D EK KK 560
Cdd:PTZ00272 453 VTRMK A GQ KS I Y YITG D SKK KL E T SPF I E QARRR G L EVL F M TEP IDEY VMQ Q V K D FE D KK FACL TKEG VHFE E S E E EK QQ 532
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 561 K EE L K EKF E G LCK VI K D VLGDKVEKVIVS D R VVD SPC C LVT G E Y GW T A N ME R IM KA QALRDSSMA G YM S SKKTME I NP EN 640
Cdd:PTZ00272 533 R EE E K AAC E K LCK TM K E VLGDKVEKVIVS E R LST SPC I LVT S E F GW S A H ME Q IM RN QALRDSSMA Q YM M SKKTME L NP RH 612
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 641 S I MD ELR K R AD AD K NDK S VKDLV L LLF E T A LLTSGF S L DE P NTFGS RI H RM L KLGLS I D DDDAVE A D A em P PL E D --- DA 717
Cdd:PTZ00272 613 P I IK ELR R R VG AD E NDK A VKDLV F LLF D T S LLTSGF Q L ED P TGYAE RI N RM I KLGLS L D EEEEEA A E A -- P VA E T apa EV 690
730
....*....|.
gi 334188442 718 D A EG S K ME E VD 728
Cdd:PTZ00272 691 T A GT S S ME Q VD 701
Name
Accession
Description
Interval
E-value
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
5-728
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 954.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 5 ETFAFQAEINQL L SLIINTFYSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl A L DKIR FE SLTD K S 84
Cdd:PTZ00272 3 ETFAFQAEINQL M SLIINTFYSNKEIFLRELISN A SD ----------------------------- A C DKIR YQ SLTD P S 53
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 85 K L DGQ P E L F I HII PDK T N N TLT II D S GIGMTKADLVNNLGTIARSGTK E FMEAL A AG A D V SMIGQFGVGFYSAYLVAD K V 164
Cdd:PTZ00272 54 V L GES P R L C I RVV PDK E N K TLT VE D N GIGMTKADLVNNLGTIARSGTK A FMEAL E AG G D M SMIGQFGVGFYSAYLVAD R V 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 165 V VT T K H N D DE Q YVWES Q AGG S FT V T r D T SGETLG RGT KMV L Y LKEDQ L EYLE E RRLK D L V KKHSEFI S Y P I S L WI EKT -- 242
Cdd:PTZ00272 134 T VT S K N N S DE S YVWES S AGG T FT I T - S T PESDMK RGT RIT L H LKEDQ M EYLE P RRLK E L I KKHSEFI G Y D I E L MV EKT te 212
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 243 -- IEK E ISD D EEEEEKKD EE G KVEEV D E EK E KEE KK K KK I KEV SH E WDLV NK Q KP I W M R K P EEIN KEEYAAFYK SL SNDW 320
Cdd:PTZ00272 213 ke VTD E DEE D TKKADEDG EE P KVEEV K E GD E GKK KK T KK V KEV TK E YEVQ NK H KP L W T R D P KDVT KEEYAAFYK AI SNDW 292
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 321 E EHL A V KHFSVEGQLEF KA I L FVPKRAPFD L F DTK KK P NNIKLYVRRVFIMDNCED II P EY LGFVKG I VDSEDLPLNISR 400
Cdd:PTZ00272 293 E DPA A T KHFSVEGQLEF RS I M FVPKRAPFD M F EPN KK R NNIKLYVRRVFIMDNCED LC P DW LGFVKG V VDSEDLPLNISR 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 401 E T LQQNKILKVIRKN L VKKCLE L F F E I AENKEDY NK FYE A F S KN L KLGIHED SQ NR T K IA ELLR YH ST K SG D E L T S LKDY 480
Cdd:PTZ00272 373 E N LQQNKILKVIRKN I VKKCLE M F D E V AENKEDY KQ FYE Q F G KN I KLGIHED TA NR K K LM ELLR FY ST E SG E E M T T LKDY 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 481 VTRMK E GQ ND I F YITG E SKK AV E N SPF L E KLKKK G I EVL Y M VDA IDEY AIG Q L K E FE G KK LVSA TKEG LKLD E T E D EK KK 560
Cdd:PTZ00272 453 VTRMK A GQ KS I Y YITG D SKK KL E T SPF I E QARRR G L EVL F M TEP IDEY VMQ Q V K D FE D KK FACL TKEG VHFE E S E E EK QQ 532
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 561 K EE L K EKF E G LCK VI K D VLGDKVEKVIVS D R VVD SPC C LVT G E Y GW T A N ME R IM KA QALRDSSMA G YM S SKKTME I NP EN 640
Cdd:PTZ00272 533 R EE E K AAC E K LCK TM K E VLGDKVEKVIVS E R LST SPC I LVT S E F GW S A H ME Q IM RN QALRDSSMA Q YM M SKKTME L NP RH 612
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 641 S I MD ELR K R AD AD K NDK S VKDLV L LLF E T A LLTSGF S L DE P NTFGS RI H RM L KLGLS I D DDDAVE A D A em P PL E D --- DA 717
Cdd:PTZ00272 613 P I IK ELR R R VG AD E NDK A VKDLV F LLF D T S LLTSGF Q L ED P TGYAE RI N RM I KLGLS L D EEEEEA A E A -- P VA E T apa EV 690
730
....*....|.
gi 334188442 718 D A EG S K ME E VD 728
Cdd:PTZ00272 691 T A GT S S ME Q VD 701
HSP90
pfam00183 Hsp90 protein;
213-720
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 817.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 213 EYLEE RRL K D LVKK H SEFI SY PI S LW I EK TI E K E IS D D EEEEE KKD EE GKVEEVDE E K E K EE KK KKK I --- KE VSH EW D L 289
Cdd:pfam00183 1 EYLEE KKI K E LVKK Y SEFI NF PI Y LW V EK EE E V E VP D E EEEEE EEE EE EEDDDPKV E E E D EE EE KKK T kkv KE TVW EW E L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 290 V NK Q KPIW M R K P E E INK EEYA A FYKSLS N DWE EH LAVKHFSVEG QL EFK AI LF V PKRAPFDLF DT KKK P NNIKLYVRRVF 369
Cdd:pfam00183 81 L NK T KPIW T R N P K E VTE EEYA E FYKSLS K DWE DP LAVKHFSVEG EV EFK SL LF I PKRAPFDLF EN KKK K NNIKLYVRRVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 370 I M D NC ED I IPEYL G FVKG I VDS E DLPLN I SRETLQQNKILKVI R K N LV K K C L EL F F EIAE N KEDY N KF YEA F S KNLKLGI 449
Cdd:pfam00183 161 I T D DF ED L IPEYL N FVKG V VDS D DLPLN V SRETLQQNKILKVI K K K LV R K A L DM F K EIAE E KEDY K KF WKE F G KNLKLGI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 450 H EDS Q NR T K I A E LLR YH S T KSGDELTSL K DYV T RMKEGQ ND I F YITGESK KA VENSPFLE K LKKKG I EVLY MV D A IDEYA 529
Cdd:pfam00183 241 I EDS S NR N K L A K LLR FY S S KSGDELTSL D DYV S RMKEGQ KH I Y YITGESK EE VENSPFLE R LKKKG Y EVLY LT D P IDEYA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 530 IG QLKEF E GKKLV SAT KEGL K L D E T E D EKKK K EELK EK FE G L C K VI KDVLGDKVEKV I VS D R V VDSPC C LVT GE YGW T AN 609
Cdd:pfam00183 321 VQ QLKEF D GKKLV NVA KEGL E L E E D E E EKKK D EELK KE FE P L T K WL KDVLGDKVEKV V VS N R L VDSPC V LVT SQ YGW S AN 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 610 MERIMKAQALR - DSSM AG YMSSKKT M EINP ENS I MD EL R KR AD ADK N DK SV KDL V LLL F ETALL T SGFSL DE P NT F G SRI 688
Cdd:pfam00183 401 MERIMKAQALR k DSSM SS YMSSKKT L EINP RHP I IK EL L KR VE ADK D DK TA KDL A LLL Y ETALL R SGFSL ED P AS F A SRI 480
490 500 510
....*....|....*....|....*....|..
gi 334188442 689 H RMLKLGL S ID D D DA VE ADA E MPPL E DDADA E 720
Cdd:pfam00183 481 Y RMLKLGL G ID E D EI VE EED E IEEE E EEEEE E 512
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
4-697
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 733.08
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 4 A ET FA FQAE IN QLL S L I I NTF YSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl A L DK I RF ES LTD K 83
Cdd:COG0326 3 K ET GE FQAE VK QLL D L M I HSL YSNKEIFLRELISN A SD ----------------------------- A I DK L RF LA LTD P 53
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 84 SKLDGQPE L F I H I IP DK TNN TLTI I D S GIGMT KADLVN NLGTIA R SGT K EF M E A L -- AAGA D VSM IGQFGVGFYSA YL VA 161
Cdd:COG0326 54 ELKEEDGD L K I R I EV DK EAK TLTI S D N GIGMT REEVIE NLGTIA K SGT R EF L E K L kg DQKK D SDL IGQFGVGFYSA FM VA 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 162 DKV V V T T KH -- N D D E QYV WES QAG G SF T VTR dts G E TLG RGT KMV L Y LKED QL E Y LEE R RL KDLV KK H S E FI SY PI SLWI 239
Cdd:COG0326 134 DKV E V V T RS ag E D A E AVR WES DGD G EY T IEE --- A E KAE RGT EIT L H LKED AE E F LEE W RL REII KK Y S D FI PV PI KMEG 210
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 240 E KTIEK eisddeeeeekkdeegkveevdeekekeekkkkkikevsh E WDLV N KQKPI W M R KPE EI NK EEY AA FYK S L SN D 319
Cdd:COG0326 211 E EEETE ---------------------------------------- E DETI N SATAL W T R SKS EI TD EEY KE FYK H L FH D 250
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 320 W E EH L AVK H FS VEG QL E FKAI L FV PK R APFDL F D TKK K p NN IKLYV R RVFIMD NC ED II PEYL G FV K G I VDS E DLPLN I S 399
Cdd:COG0326 251 F E DP L FWI H LN VEG PF E YTGL L YI PK K APFDL Y D RDR K - GG IKLYV K RVFIMD DA ED LL PEYL R FV R G V VDS P DLPLN V S 329
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 400 RE T LQ QNKI LK V IRK NLV KK C L ELFFEI A E N - K E D Y N KF YEA F SKN LK L G IH ED SQ NR T KIA E LLR YH STK s GDELTS L K 478
Cdd:COG0326 330 RE I LQ EDRQ LK K IRK AIT KK V L DELEKL A K N d R E K Y E KF WKE F GLV LK E G AL ED FK NR E KIA D LLR FE STK - EGGYVT L A 408
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 479 D YV T RMKEGQ ND I F YITGES KK A V E N SP F LE KL K K KGIEVL YMV D A IDE YA I GQ L K EF E GKK LV S ATKEG L K LD e TED EK 558
Cdd:COG0326 409 E YV E RMKEGQ KK I Y YITGES RE A A E Q SP H LE IF K A KGIEVL LLT D P IDE FL I SH L E EF D GKK FK S VDSGD L D LD - KLE EK 487
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 559 K KK EE LK E K F EG L CKVI K DV LGDKV EK V I VS D R VV DSP C CLV TG E YGWTAN ME RIM KA QA lrdssm AGYMSS K KTM EINP 638
Cdd:COG0326 488 K ES EE EE E E F KP L LERF K EA LGDKV KD V R VS A R LT DSP A CLV AD E GDMSRR ME KML KA MG ------ QDMPEA K PIL EINP 561
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 334188442 639 ENSIMDE L RKRA D ADK ndks V KDL VL LL FET ALL TS G FS L DE P NT F GS R IHRM L KLG L S 697
Cdd:COG0326 562 NHPLVKK L AAEE D EEL ---- F KDL AE LL YDQ ALL AE G GL L ED P AA F VK R LNKL L EKA L G 616
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
14-231
1.09e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 314.84
E-value: 1.09e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 14 NQLL S LII NTF YSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl ALDK I R FE SLTD K S K LD GQ PEL F 93
Cdd:cd16927 1 NQLL D LII HSL YSNKEIFLRELISN A SD ----------------------------- ALDK L R YL SLTD P S L LD DD PEL E 51
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 94 I H I I PDK T N N TLTI I D S GIGMTK AD L V NNLGTIARSGTK E F M EAL AA GA - D VSM IGQFGVGFYSA YL VADKV V VTTK HN - 171
Cdd:cd16927 52 I R I S PDK E N R TLTI S D T GIGMTK EE L I NNLGTIARSGTK A F L EAL QE GA k D SDL IGQFGVGFYSA FM VADKV T VTTK SA g 131
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 172 DDE Q Y V WES QA GGS F T VTRDTSG et LGRGTK MV L Y LKED QL E Y LEE R R L K D LVKK H S E FI 231
Cdd:cd16927 132 DDE G Y R WES DG GGS Y T IEEAEGE -- LGRGTK IT L H LKED AK E F LEE A R I K E LVKK Y S D FI 189
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
89-208
1.21e-06
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 47.64
E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 89 QPELFIHIIP D KTNNTL T II D S G I G MTKA DL vnnlgtiarsg T K E F MEALAAGADVSM IG QF G V G FYSAYLVADKV vvtt 168
Cdd:smart00387 24 GGRITVTLER D GDHVEI T VE D N G P G IPPE DL ----------- E K I F EPFFRTDKRSRK IG GT G L G LSIVKKLVELH ---- 88
90 100 110 120
....*....|....*....|....*....|....*....|
gi 334188442 169 khnddeqyvwesqa GG SFT V TR dtsge TL G R GT KMVLY L K 208
Cdd:smart00387 89 -------------- GG EIS V ES ----- EP G G GT TFTIT L P 109
Name
Accession
Description
Interval
E-value
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
5-728
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 954.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 5 ETFAFQAEINQL L SLIINTFYSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl A L DKIR FE SLTD K S 84
Cdd:PTZ00272 3 ETFAFQAEINQL M SLIINTFYSNKEIFLRELISN A SD ----------------------------- A C DKIR YQ SLTD P S 53
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 85 K L DGQ P E L F I HII PDK T N N TLT II D S GIGMTKADLVNNLGTIARSGTK E FMEAL A AG A D V SMIGQFGVGFYSAYLVAD K V 164
Cdd:PTZ00272 54 V L GES P R L C I RVV PDK E N K TLT VE D N GIGMTKADLVNNLGTIARSGTK A FMEAL E AG G D M SMIGQFGVGFYSAYLVAD R V 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 165 V VT T K H N D DE Q YVWES Q AGG S FT V T r D T SGETLG RGT KMV L Y LKEDQ L EYLE E RRLK D L V KKHSEFI S Y P I S L WI EKT -- 242
Cdd:PTZ00272 134 T VT S K N N S DE S YVWES S AGG T FT I T - S T PESDMK RGT RIT L H LKEDQ M EYLE P RRLK E L I KKHSEFI G Y D I E L MV EKT te 212
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 243 -- IEK E ISD D EEEEEKKD EE G KVEEV D E EK E KEE KK K KK I KEV SH E WDLV NK Q KP I W M R K P EEIN KEEYAAFYK SL SNDW 320
Cdd:PTZ00272 213 ke VTD E DEE D TKKADEDG EE P KVEEV K E GD E GKK KK T KK V KEV TK E YEVQ NK H KP L W T R D P KDVT KEEYAAFYK AI SNDW 292
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 321 E EHL A V KHFSVEGQLEF KA I L FVPKRAPFD L F DTK KK P NNIKLYVRRVFIMDNCED II P EY LGFVKG I VDSEDLPLNISR 400
Cdd:PTZ00272 293 E DPA A T KHFSVEGQLEF RS I M FVPKRAPFD M F EPN KK R NNIKLYVRRVFIMDNCED LC P DW LGFVKG V VDSEDLPLNISR 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 401 E T LQQNKILKVIRKN L VKKCLE L F F E I AENKEDY NK FYE A F S KN L KLGIHED SQ NR T K IA ELLR YH ST K SG D E L T S LKDY 480
Cdd:PTZ00272 373 E N LQQNKILKVIRKN I VKKCLE M F D E V AENKEDY KQ FYE Q F G KN I KLGIHED TA NR K K LM ELLR FY ST E SG E E M T T LKDY 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 481 VTRMK E GQ ND I F YITG E SKK AV E N SPF L E KLKKK G I EVL Y M VDA IDEY AIG Q L K E FE G KK LVSA TKEG LKLD E T E D EK KK 560
Cdd:PTZ00272 453 VTRMK A GQ KS I Y YITG D SKK KL E T SPF I E QARRR G L EVL F M TEP IDEY VMQ Q V K D FE D KK FACL TKEG VHFE E S E E EK QQ 532
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 561 K EE L K EKF E G LCK VI K D VLGDKVEKVIVS D R VVD SPC C LVT G E Y GW T A N ME R IM KA QALRDSSMA G YM S SKKTME I NP EN 640
Cdd:PTZ00272 533 R EE E K AAC E K LCK TM K E VLGDKVEKVIVS E R LST SPC I LVT S E F GW S A H ME Q IM RN QALRDSSMA Q YM M SKKTME L NP RH 612
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 641 S I MD ELR K R AD AD K NDK S VKDLV L LLF E T A LLTSGF S L DE P NTFGS RI H RM L KLGLS I D DDDAVE A D A em P PL E D --- DA 717
Cdd:PTZ00272 613 P I IK ELR R R VG AD E NDK A VKDLV F LLF D T S LLTSGF Q L ED P TGYAE RI N RM I KLGLS L D EEEEEA A E A -- P VA E T apa EV 690
730
....*....|.
gi 334188442 718 D A EG S K ME E VD 728
Cdd:PTZ00272 691 T A GT S S ME Q VD 701
HSP90
pfam00183 Hsp90 protein;
213-720
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 817.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 213 EYLEE RRL K D LVKK H SEFI SY PI S LW I EK TI E K E IS D D EEEEE KKD EE GKVEEVDE E K E K EE KK KKK I --- KE VSH EW D L 289
Cdd:pfam00183 1 EYLEE KKI K E LVKK Y SEFI NF PI Y LW V EK EE E V E VP D E EEEEE EEE EE EEDDDPKV E E E D EE EE KKK T kkv KE TVW EW E L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 290 V NK Q KPIW M R K P E E INK EEYA A FYKSLS N DWE EH LAVKHFSVEG QL EFK AI LF V PKRAPFDLF DT KKK P NNIKLYVRRVF 369
Cdd:pfam00183 81 L NK T KPIW T R N P K E VTE EEYA E FYKSLS K DWE DP LAVKHFSVEG EV EFK SL LF I PKRAPFDLF EN KKK K NNIKLYVRRVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 370 I M D NC ED I IPEYL G FVKG I VDS E DLPLN I SRETLQQNKILKVI R K N LV K K C L EL F F EIAE N KEDY N KF YEA F S KNLKLGI 449
Cdd:pfam00183 161 I T D DF ED L IPEYL N FVKG V VDS D DLPLN V SRETLQQNKILKVI K K K LV R K A L DM F K EIAE E KEDY K KF WKE F G KNLKLGI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 450 H EDS Q NR T K I A E LLR YH S T KSGDELTSL K DYV T RMKEGQ ND I F YITGESK KA VENSPFLE K LKKKG I EVLY MV D A IDEYA 529
Cdd:pfam00183 241 I EDS S NR N K L A K LLR FY S S KSGDELTSL D DYV S RMKEGQ KH I Y YITGESK EE VENSPFLE R LKKKG Y EVLY LT D P IDEYA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 530 IG QLKEF E GKKLV SAT KEGL K L D E T E D EKKK K EELK EK FE G L C K VI KDVLGDKVEKV I VS D R V VDSPC C LVT GE YGW T AN 609
Cdd:pfam00183 321 VQ QLKEF D GKKLV NVA KEGL E L E E D E E EKKK D EELK KE FE P L T K WL KDVLGDKVEKV V VS N R L VDSPC V LVT SQ YGW S AN 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 610 MERIMKAQALR - DSSM AG YMSSKKT M EINP ENS I MD EL R KR AD ADK N DK SV KDL V LLL F ETALL T SGFSL DE P NT F G SRI 688
Cdd:pfam00183 401 MERIMKAQALR k DSSM SS YMSSKKT L EINP RHP I IK EL L KR VE ADK D DK TA KDL A LLL Y ETALL R SGFSL ED P AS F A SRI 480
490 500 510
....*....|....*....|....*....|..
gi 334188442 689 H RMLKLGL S ID D D DA VE ADA E MPPL E DDADA E 720
Cdd:pfam00183 481 Y RMLKLGL G ID E D EI VE EED E IEEE E EEEEE E 512
PRK05218
PRK05218 heat shock protein 90; Provisional
2-697
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 746.94
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 2 ADA ET FA FQAE IN QLL S L I I NTF YSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl A L DK I RFE S LT 81
Cdd:PRK05218 1 MAM ET GE FQAE VK QLL H L M I HSL YSNKEIFLRELISN A SD ----------------------------- A I DK L RFE A LT 51
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 82 D KSKLD G QPE L F I H I IP DK TNN TLTI I D S GIGMT KADLVN NLGTIA R SGTKEF M E A L -- AAGA D VSM IGQFGVGFYSA YL 159
Cdd:PRK05218 52 D PALYE G DGD L K I R I SF DK EAR TLTI S D N GIGMT REEVIE NLGTIA K SGTKEF L E K L kg DQKK D SQL IGQFGVGFYSA FM 131
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 160 VADKV V V T T KH -- NDD E QYV WES QAG G SF T VT r DTSG E T lg RGT KMV L Y LKED QL E Y L E E R R LKDLV KK H S E FI SY PI S L 237
Cdd:PRK05218 132 VADKV T V I T RS ag PAA E AVR WES DGE G EY T IE - EIEK E E -- RGT EIT L H LKED ED E F L D E W R IRSII KK Y S D FI PV PI K L 208
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 238 WI E ktiekeisddeeeeekkdeegkveevdeekekeekkkkkikevsh E WDLV N KQKPI W M R KPE EI NK EEY AA FYK S L S 317
Cdd:PRK05218 209 EK E --------------------------------------------- E EETI N SASAL W T R SKS EI TD EEY KE FYK H L A 243
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 318 N D WEEH L AVK H FS VEG QL E FKAI L FV PK R APFDLF DTKK K p NNI KLYV R RVFIMD NC E DII PEYL G FVKG IV DSEDLPLN 397
Cdd:PRK05218 244 H D FDDP L FWI H NN VEG PF E YTGL L YI PK K APFDLF NRDR K - GGL KLYV K RVFIMD DA E ELL PEYL R FVKG VI DSEDLPLN 322
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 398 I SRE T LQ QNKIL K V IRK NLV KK C L ELFFEI A E N - K E D Y N KF YEA F SKN LK L G IH ED SQ NR T K I A E LLR YH ST KS G d ELT S 476
Cdd:PRK05218 323 V SRE I LQ EDRVV K K IRK AIT KK V L DELEKL A K N d R E K Y E KF WKE F GPV LK E G LY ED FA NR E K L A K LLR FA ST HE G - KYV S 401
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 477 L KD YV T RMKEGQ ND I F YITG E S KK A VE NSP F LE KL KKKGIEVL YMV D A IDE YA I GQ L K EF E GK KLV S ATKEG L K L DETED 556
Cdd:PRK05218 402 L AE YV E RMKEGQ KK I Y YITG D S RE A AK NSP H LE LF KKKGIEVL LLT D P IDE FW I SY L E EF D GK PFK S VARGD L D L GKEDE 481
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 557 E K K KKE E LK E - K F EG L CKVI K DV LGDKV EK V IV S D R VV DSP C CLV TG E YGWTAN ME RIM KA Q alrdss MAGYMS SK KTM E 635
Cdd:PRK05218 482 E E K EEK E EA E e E F KP L LERL K EA LGDKV KD V RL S H R LT DSP A CLV AD E GDMSTQ ME KLL KA A ------ GQEVPE SK PIL E 555
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334188442 636 INP ENSIMDE L RKR AD AD K ndks V KDL VL LL FET ALL TS G F SL DE P NT F GS R IHRM L KLG L S 697
Cdd:PRK05218 556 INP NHPLVKK L ADE AD EA K ---- F KDL AE LL YDQ ALL AE G G SL ED P AA F VK R LNEL L LKL L A 613
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
4-697
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 733.08
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 4 A ET FA FQAE IN QLL S L I I NTF YSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl A L DK I RF ES LTD K 83
Cdd:COG0326 3 K ET GE FQAE VK QLL D L M I HSL YSNKEIFLRELISN A SD ----------------------------- A I DK L RF LA LTD P 53
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 84 SKLDGQPE L F I H I IP DK TNN TLTI I D S GIGMT KADLVN NLGTIA R SGT K EF M E A L -- AAGA D VSM IGQFGVGFYSA YL VA 161
Cdd:COG0326 54 ELKEEDGD L K I R I EV DK EAK TLTI S D N GIGMT REEVIE NLGTIA K SGT R EF L E K L kg DQKK D SDL IGQFGVGFYSA FM VA 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 162 DKV V V T T KH -- N D D E QYV WES QAG G SF T VTR dts G E TLG RGT KMV L Y LKED QL E Y LEE R RL KDLV KK H S E FI SY PI SLWI 239
Cdd:COG0326 134 DKV E V V T RS ag E D A E AVR WES DGD G EY T IEE --- A E KAE RGT EIT L H LKED AE E F LEE W RL REII KK Y S D FI PV PI KMEG 210
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 240 E KTIEK eisddeeeeekkdeegkveevdeekekeekkkkkikevsh E WDLV N KQKPI W M R KPE EI NK EEY AA FYK S L SN D 319
Cdd:COG0326 211 E EEETE ---------------------------------------- E DETI N SATAL W T R SKS EI TD EEY KE FYK H L FH D 250
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 320 W E EH L AVK H FS VEG QL E FKAI L FV PK R APFDL F D TKK K p NN IKLYV R RVFIMD NC ED II PEYL G FV K G I VDS E DLPLN I S 399
Cdd:COG0326 251 F E DP L FWI H LN VEG PF E YTGL L YI PK K APFDL Y D RDR K - GG IKLYV K RVFIMD DA ED LL PEYL R FV R G V VDS P DLPLN V S 329
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 400 RE T LQ QNKI LK V IRK NLV KK C L ELFFEI A E N - K E D Y N KF YEA F SKN LK L G IH ED SQ NR T KIA E LLR YH STK s GDELTS L K 478
Cdd:COG0326 330 RE I LQ EDRQ LK K IRK AIT KK V L DELEKL A K N d R E K Y E KF WKE F GLV LK E G AL ED FK NR E KIA D LLR FE STK - EGGYVT L A 408
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 479 D YV T RMKEGQ ND I F YITGES KK A V E N SP F LE KL K K KGIEVL YMV D A IDE YA I GQ L K EF E GKK LV S ATKEG L K LD e TED EK 558
Cdd:COG0326 409 E YV E RMKEGQ KK I Y YITGES RE A A E Q SP H LE IF K A KGIEVL LLT D P IDE FL I SH L E EF D GKK FK S VDSGD L D LD - KLE EK 487
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 559 K KK EE LK E K F EG L CKVI K DV LGDKV EK V I VS D R VV DSP C CLV TG E YGWTAN ME RIM KA QA lrdssm AGYMSS K KTM EINP 638
Cdd:COG0326 488 K ES EE EE E E F KP L LERF K EA LGDKV KD V R VS A R LT DSP A CLV AD E GDMSRR ME KML KA MG ------ QDMPEA K PIL EINP 561
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 334188442 639 ENSIMDE L RKRA D ADK ndks V KDL VL LL FET ALL TS G FS L DE P NT F GS R IHRM L KLG L S 697
Cdd:COG0326 562 NHPLVKK L AAEE D EEL ---- F KDL AE LL YDQ ALL AE G GL L ED P AA F VK R LNKL L EKA L G 616
PTZ00130
PTZ00130 heat shock protein 90; Provisional
5-726
1.03e-163
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 492.25
E-value: 1.03e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 5 E TFAF Q A E INQ L LSL I I N TF Y SN KE I FLRELISN SS D vrslslstllytcvsrlidladgsvdlgl AL D KIRF E SL T D K S 84
Cdd:PTZ00130 66 E QHQY Q T E VTR L MDI I V N SL Y TQ KE V FLRELISN AA D ----------------------------- AL E KIRF L SL S D E S 116
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 85 K L DGQPE L F I H I IPD K TN N T L T I I D S GIGMTK A DL V NNLGTIA R SGT KE F M EA LA - A G A D V S M IGQFGVGFYSA Y LVADK 163
Cdd:PTZ00130 117 V L GEEKK L E I R I SAN K EK N I L S I T D T GIGMTK E DL I NNLGTIA K SGT SN F L EA IS k S G G D M S L IGQFGVGFYSA F LVADK 196
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 164 V V V T TK H N D DEQY V WES Q A GGS FT VTR D TS G E TL G RGT KMV L Y LKED QLEYLEERR L K DL VK K H S E FI S YPI S L w IEKTI 243
Cdd:PTZ00130 197 V I V Y TK N N N DEQY I WES T A DAK FT IYK D PR G S TL K RGT RIS L H LKED ATNLMNDKK L V DL IS K Y S Q FI Q YPI Y L - LHENV 275
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 244 EK E ISDDEEEE E KKDEEGKVEEVD EE KEKEE KK KKKIKEVSHE W D L V N K QKPIW M R K P E E INK E E Y AA F YKS LS NDWE E H 323
Cdd:PTZ00130 276 YT E EVLADIAK E MENDPNYDSVKV EE TDDPN KK TRTVEKKVKK W K L M N E QKPIW L R P P K E LTD E D Y KK F FSV LS GFND E P 355
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 324 L AVK HF SV EG QL EFK AILFV P K RAP FDLFDTKK K P N N IKLYVRRV FIM D NCEDII P E Y LG FVKG I VDS E DLPLN I SRE T L 403
Cdd:PTZ00130 356 L YHI HF FA EG EI EFK CLIYI P S RAP SINDHLFT K Q N S IKLYVRRV LVA D EFVEFL P R Y MS FVKG V VDS D DLPLN V SRE Q L 435
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 404 QQNKILK VIR K NL V K K C L EL F FEI ---- AE NKE D -------------------------- Y NKF Y EAFS K N LK L G IH ED S 453
Cdd:PTZ00130 436 QQNKILK AVS K RI V R K I L DT F RTL ykeg KK NKE T lraelaketdeekkkeiqkkinepst Y KLI Y KEYR K Y LK T G CY ED D 515
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 454 Q NR T KI AE LL RYHSTKSGDEL t SL KD Y VTR MK EG Q ND I F Y IT G E S KKAVENS P F L EKL KKK G I E V LYMVDAI DE YAIGQL 533
Cdd:PTZ00130 516 I NR N KI VK LL LFKTMLHPKSI - SL DT Y IEN MK PD Q KF I Y Y AS G D S YEYLSKI P Q L QIF KKK N I D V VFLTESV DE SCVQRV 594
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 534 K E FE GKK LV S AT K EGLKLDE TEDEKKK K E EL K EKFEG L CK VI K D V L GDKVE KV IV S D R V VD S PC CL V TG E Y G WTAN ME RI 613
Cdd:PTZ00130 595 Q E YD GKK FK S IQ K GEITFEL TEDEKKK E E KV K KMYKA L ID VI S D T L RNQIF KV EI S R R L VD A PC AV V ST E W G LSGQ ME KL 674
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 614 MK AQ a LRD S SMAGY MS SK K TM EINP ENS IM DE L R KR ADADKN D KSVKDLVLLLFET A L L T SGF S L DEPNTFGSRI -- H RM 691
Cdd:PTZ00130 675 MK IN - VNN S DQIKA MS GQ K IL EINP DHP IM ID L L KR SVSNPK D SQLTESIKIIYQS A K L A SGF D L EDTADLAQIV yd H IN 753
730 740 750
....*....|....*....|....*....|....*..
gi 334188442 692 L KLG L -- SIDD DD AVE A DA E MPPL E DDADAE G S K ME E 726
Cdd:PTZ00130 754 Q KLG V dn NLKI DD LDP A IF E TKKI E QEDSPD G Q K FH E 790
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
14-231
1.09e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 314.84
E-value: 1.09e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 14 NQLL S LII NTF YSNKEIFLRELISN S SD vrslslstllytcvsrlidladgsvdlgl ALDK I R FE SLTD K S K LD GQ PEL F 93
Cdd:cd16927 1 NQLL D LII HSL YSNKEIFLRELISN A SD ----------------------------- ALDK L R YL SLTD P S L LD DD PEL E 51
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 94 I H I I PDK T N N TLTI I D S GIGMTK AD L V NNLGTIARSGTK E F M EAL AA GA - D VSM IGQFGVGFYSA YL VADKV V VTTK HN - 171
Cdd:cd16927 52 I R I S PDK E N R TLTI S D T GIGMTK EE L I NNLGTIARSGTK A F L EAL QE GA k D SDL IGQFGVGFYSA FM VADKV T VTTK SA g 131
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 172 DDE Q Y V WES QA GGS F T VTRDTSG et LGRGTK MV L Y LKED QL E Y LEE R R L K D LVKK H S E FI 231
Cdd:cd16927 132 DDE G Y R WES DG GGS Y T IEEAEGE -- LGRGTK IT L H LKED AK E F LEE A R I K E LVKK Y S D FI 189
PRK14083
PRK14083 HSP90 family protein; Provisional
8-416
3.65e-24
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 107.72
E-value: 3.65e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 8 A FQ AEINQLLS L IINTF YS NKEIFL REL IS N SS D vrslslstllytcvsrlidladgsvdlglaldkirfe SL T DKSK LD 87
Cdd:PRK14083 4 R FQ VDLRGVID L LSRHL YS SPRVYV REL LQ N AV D ------------------------------------- AI T ARRA LD 46
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 88 GQPELF I H I IPDKTNN - TL TII D S GIG M T KADLVNN L G TI A RS GTKE fm E A L AAGAD v SMI GQFG V G FY S AY LVAD KV VV 166
Cdd:PRK14083 47 PTAPGR I R I ELTDAGG g TL IVE D N GIG L T EEEVHEF L A TI G RS SKRD -- E N L GFARN - DFL GQFG I G LL S CF LVAD EI VV 123
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 167 TTKHND D EQY V - W ESQ A G G SFT V t R DTSG E TLGR GT KMV L YLKE D QL E Y LE ERRLKD L V KK HSEFISY PI SLWI EK tiek 245
Cdd:PRK14083 124 VSRSAK D GPA V e W RGK A D G TYS V - R KLET E RAEP GT TVY L RPRP D AE E W LE RETVEE L A KK YGSLLPV PI RVEG EK ---- 198
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 246 eisddeeeeekkdeegkveevdeekekeekkkkkikevshew DL VN KQK P I W M R KPE -- E INK E EYA A FYKS L SN dw EEH 323
Cdd:PRK14083 199 ------------------------------------------ GG VN ETP P P W T R DYP dp E TRR E ALL A YGEE L LG -- FTP 234
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 324 L A V KHFS V E - G Q LE fk AILF V - P KRAPF dlfdtk KKPNNIKL Y VR R VFIMDNC E DII P EYLG FV KGI V DSED L PLNI SRE 401
Cdd:PRK14083 235 L D V IPLD V P s G G LE -- GVAY V l P YAVSP ------ AARRKHRV Y LK R MLLSEEA E NLL P DWAF FV RCV V NTDE L RPTA SRE 306
410
....*....|....*
gi 334188442 402 T L QQNKI L KVI R KN L 416
Cdd:PRK14083 307 A L YEDDA L AAV R EE L 321
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
89-208
1.21e-06
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 47.64
E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 89 QPELFIHIIP D KTNNTL T II D S G I G MTKA DL vnnlgtiarsg T K E F MEALAAGADVSM IG QF G V G FYSAYLVADKV vvtt 168
Cdd:smart00387 24 GGRITVTLER D GDHVEI T VE D N G P G IPPE DL ----------- E K I F EPFFRTDKRSRK IG GT G L G LSIVKKLVELH ---- 88
90 100 110 120
....*....|....*....|....*....|....*....|
gi 334188442 169 khnddeqyvwesqa GG SFT V TR dtsge TL G R GT KMVLY L K 208
Cdd:smart00387 89 -------------- GG EIS V ES ----- EP G G GT TFTIT L P 109
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
94-175
2.56e-04
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 41.55
E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 94 I HIIPDKTNN T - LT I I D S G I GM TKAD L V N N L G t I A R S GTK efmeala A GADVSMI G QF G V G FYS A Y L V - AD K VV VT T K HN 171
Cdd:pfam13589 22 I EVNKNRGGG T e IV I E D D G H GM SPEE L I N A L R - L A T S AKE ------- A KRGSTDL G RY G I G LKL A S L S l GA K LT VT S K KE 93
....
gi 334188442 172 DDEQ 175
Cdd:pfam13589 94 GKSS 97
HATPase_c
pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
90-211
4.11e-03
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain]
Cd Length: 109
Bit Score: 37.35
E-value: 4.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334188442 90 P E LFIHIIPDK t NN TLT II D S GIG MTKA DL vnnlgti A R SGTK e F ME alaag AD VSMI G QF G V G FY sayl VAD K V V vttk 169
Cdd:pfam02518 25 G E ITVTLSEGG - EL TLT VE D N GIG IPPE DL ------- P R IFEP - F ST ----- AD KRGG G GT G L G LS ---- IVR K L V ---- 82
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 334188442 170 hnddeqyvwe SQA GG SF TV T rdtsg ETL G R GT KMV L Y L KED Q 211
Cdd:pfam02518 83 ---------- ELL GG TI TV E ----- SEP G G GT TVT L T L PLA Q 109
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
