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Conserved domains on  [gi|329663159|ref|NP_001192474|]
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dimethylglycine dehydrogenase, mitochondrial [Bos taurus]

Protein Classification

GcvT family protein( domain architecture ID 11429831)

GcvT (glycine cleavage system T) family protein similar to mammalian dimethylglycine dehydrogenase that catalyzes the FAD-dependent demethylation of N,N-dimethylglycine to sarcosine, and pyruvate dehydrogenase phosphatase regulatory subunit

CATH:  3.30.1360.120|3.30.70.140|3.30.70.1400|3.30.9.10|2.40.30.110
PubMed:  8219277
SCOP:  4000128|4000062

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 489-857 3.75e-119

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


:

Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 365.94  E-value: 3.75e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 489 GWEQPHWFYkpgqdpgyrpsfhrtnwfEPVGSEYQQVMQRVGVIDLSPFGKFNIKGQDSIRLLDHLFANVIPK--VGFTN 566
Cdd:COG0404   25 GWEMPVQYP------------------GGVIAEHLAVREAVGLFDVSHMGKIEVTGPDAAAFLDRLVTNDVSKlkPGRAR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 567 ISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEEeAIKGGYDVEIKNITDELGVLGVAGPYSRKVLQKLTS 646
Cdd:COG0404   87 YTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEE-HLPPDFDVTITDVTDDWALLAVQGPKAREVLAKLTD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 647 EDLSDnvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSAALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRA 726
Cdd:COG0404  166 ADLSA--LPFMSFREGTVAGVPVRVSRTGYTGEDGFEIYVPAEDAEALWDALLEAGEEFGVKPCGLGARDTLRLEAGYPL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 727 WGSEMNCDTNPLEAGLESFVKLNKPaDFIGKQALKQIKAKGLKRRLVCLTLaTDDVDPEGNESIWYDGKVVGNTTSGSYS 806
Cdd:COG0404  244 YGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL-DGRGVPRAGAPVLADGEVVGEVTSGTFS 321

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 329663159 807 YRIQKSLAFAYVPVELSKVGQQVEVELLGKNYPAVVIQEPLVltEPTRSRL 857
Cdd:COG0404  322 PTLGKSIALAYVPAGLARPGTELEVEIRGKRVPAEVVKPPFY--DPEGERL 370
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
49-431 4.55e-91

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 292.19  E-value: 4.55e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAGSTWHAAGL--TTYFHPGIN-LKKIHYYSIKLYEKLEEETGQ 125
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQlrPGLAALADRaLVRLAREALDLWRELAAELGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 126 VVGFHQPGSIRIATTPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLNMNKILAGLYNPGDGHIDPYSLTMALAAG 205
Cdd:COG0665   81 DCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 206 ARKYGALLKYPAPVTSLKPRSDGTWDVETPHGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYIITSTIPEvkalK 285
Cdd:COG0665  161 ARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPD----L 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 286 RELPVLRDleGSFYLRQERDG-LLFGPYESqekmkvqdswvtsgvppgFGKELFESDLDRIMEHVEAAMDLVPVLKKADI 364
Cdd:COG0665  237 PLRPVLDD--TGVYLRPTADGrLLVGGTAE------------------PAGFDRAPTPERLEALLRRLRRLFPALADAEI 296

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 329663159 365 IRIVNGPITYSPDILPMVGPHQGVRNYWVAVGF-GYGIIHAGGVGKYLSDWILHREPPFDLIELDPNR 431
Cdd:COG0665  297 VRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHgGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
FAO_M pfam16350
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ...
 419-472 1.67e-13

FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).


:

Pssm-ID: 465100  Cd Length: 56  Bit Score: 65.55  E-value: 1.67e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 329663159  419 EPPFDLIELDPNRYGK-WTTAEYTEAKARESYGFNNIVGYPKEERFAGRPtQRVS 472
Cdd:pfam16350   3 EPPIDLWECDIRRFGPhQNNREYLRERVAENYGEVYDIHHPNEEREAGRP-LRTS 56
 
Name Accession Description Interval E-value
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 489-857 3.75e-119

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 365.94  E-value: 3.75e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 489 GWEQPHWFYkpgqdpgyrpsfhrtnwfEPVGSEYQQVMQRVGVIDLSPFGKFNIKGQDSIRLLDHLFANVIPK--VGFTN 566
Cdd:COG0404   25 GWEMPVQYP------------------GGVIAEHLAVREAVGLFDVSHMGKIEVTGPDAAAFLDRLVTNDVSKlkPGRAR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 567 ISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEEeAIKGGYDVEIKNITDELGVLGVAGPYSRKVLQKLTS 646
Cdd:COG0404   87 YTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEE-HLPPDFDVTITDVTDDWALLAVQGPKAREVLAKLTD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 647 EDLSDnvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSAALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRA 726
Cdd:COG0404  166 ADLSA--LPFMSFREGTVAGVPVRVSRTGYTGEDGFEIYVPAEDAEALWDALLEAGEEFGVKPCGLGARDTLRLEAGYPL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 727 WGSEMNCDTNPLEAGLESFVKLNKPaDFIGKQALKQIKAKGLKRRLVCLTLaTDDVDPEGNESIWYDGKVVGNTTSGSYS 806
Cdd:COG0404  244 YGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL-DGRGVPRAGAPVLADGEVVGEVTSGTFS 321

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 329663159 807 YRIQKSLAFAYVPVELSKVGQQVEVELLGKNYPAVVIQEPLVltEPTRSRL 857
Cdd:COG0404  322 PTLGKSIALAYVPAGLARPGTELEVEIRGKRVPAEVVKPPFY--DPEGERL 370
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
49-431 4.55e-91

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 292.19  E-value: 4.55e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAGSTWHAAGL--TTYFHPGIN-LKKIHYYSIKLYEKLEEETGQ 125
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQlrPGLAALADRaLVRLAREALDLWRELAAELGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 126 VVGFHQPGSIRIATTPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLNMNKILAGLYNPGDGHIDPYSLTMALAAG 205
Cdd:COG0665   81 DCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 206 ARKYGALLKYPAPVTSLKPRSDGTWDVETPHGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYIITSTIPEvkalK 285
Cdd:COG0665  161 ARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPD----L 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 286 RELPVLRDleGSFYLRQERDG-LLFGPYESqekmkvqdswvtsgvppgFGKELFESDLDRIMEHVEAAMDLVPVLKKADI 364
Cdd:COG0665  237 PLRPVLDD--TGVYLRPTADGrLLVGGTAE------------------PAGFDRAPTPERLEALLRRLRRLFPALADAEI 296

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 329663159 365 IRIVNGPITYSPDILPMVGPHQGVRNYWVAVGF-GYGIIHAGGVGKYLSDWILHREPPFDLIELDPNR 431
Cdd:COG0665  297 VRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHgGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
GCV_T pfam01571
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ...
 488-745 8.55e-68

Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.


Pssm-ID: 460255  Cd Length: 254  Bit Score: 225.93  E-value: 8.55e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  488 SGWEQPHWFYKPGQDpgyrpsfhrtnwfepvgSEYQQVMQRVGVIDLSPFGKFNIKGQDSIRLLDHLFANVI--PKVGFT 565
Cdd:pfam01571  15 AGWEMPVQYGSNGIL-----------------AEHRAVREAAGLFDVSHMGKIEVSGPDAAAFLQRLTTNDVskLKPGRA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  566 NISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEEEAikGGYDVEIKNITDELGVLGVAGPYSRKVLQKLT 645
Cdd:pfam01571  78 TYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHA--EKLDVVVVDVTDDYALLALQGPKAREVLEKLT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  646 SEDLSDNvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSAALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFR 725
Cdd:pfam01571 156 DGDLLEA-LPFFSFREIEIGGVPVRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELGLRPAGLGARDSLRLEAGLP 234

                         250       260
                  ....*....|....*....|
gi 329663159  726 AWGSEMNCDTNPLEAGLESF 745
Cdd:pfam01571 235 LYGHDLDEETTPLEAGLGWA 254
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 53-414 3.62e-65

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 221.89  E-value: 3.62e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159   53 VIIGGGCVGVSLAYHLAKAGMkDVVLLEK-SELTAGSTWHAAGLttyFHPGI------NLKKIHYYSIKLYEKLEEETGQ 125
Cdd:pfam01266   3 VVIGGGIVGLSTAYELARRGL-SVTLLERgDDPGSGASGRNAGL---IHPGLrylepsELARLALEALDLWEELEEELGI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  126 VVGFHQPGSIRIATTPVRvDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLnmNKILAGLYNPGDGHIDPYSLTMALAAG 205
Cdd:pfam01266  79 DCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLL--PGLRGGLFYPDGGHVDPARLLRALARA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  206 ARKYGALLKYPAPVTSLKpRSDGTWDVETPHgsmRANRIVNAAGFWAREVGkMIGLEHPLIPVQHQYIITSTIPEvKALK 285
Cdd:pfam01266 156 AEALGVRIIEGTEVTGIE-EEGGVWGVVTTG---EADAVVNAAGAWADLLA-LPGLRLPVRPVRGQVLVLEPLPE-ALLI 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  286 RELPVLRDLEGSFYLRQERDG-LLFGPYEsqekmkvqdswvtsgvpPGFGKELFESDLDRIMEHVEAAMDLVPVLkkADI 364
Cdd:pfam01266 230 LPVPITVDPGRGVYLRPRADGrLLLGGTD-----------------EEDGFDDPTPDPEEIEELLEAARRLFPAL--ADI 290

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 329663159  365 IRIVNGPITYsPDILPMVGPHqGVRNYWVAVGF-GYGIIHAGGVGKYLSDW 414
Cdd:pfam01266 291 ERAWAGLRPL-PDGLPIIGRP-GSPGLYLATGHgGHGLTLAPGIGKLLAEL 339
gcvT PRK00389
glycine cleavage system aminomethyltransferase GcvT;
474-848 7.64e-64

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 234742 [Multi-domain]  Cd Length: 359  Bit Score: 218.83  E-value: 7.64e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 474 LYET-LESKCSMGFHSGWEQPHWFykpgqdpgyrpsfhrtnwfepvGS---EYQQVMQRVGVIDLSPFGKFNIKGQDSIR 549
Cdd:PRK00389   7 LYDLhVALGAKMVDFGGWEMPVQY----------------------GSiieEHHAVRTDAGLFDVSHMGEVDVTGPDALA 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 550 LLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEEEAIkgGYDVEIKNITDEL 627
Cdd:PRK00389  65 FLQYLLANDVSKlkPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVVNAANREKDLAWIKSHAA--GFGVEVTDRSDDL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 628 GVLGVAGPYSRKVLQKLTSEDLSDnvFKFLQtkSLKVSNIPVTAIRIS---YTGELGWELYHRREDSAALYDAIMNAGqe 704
Cdd:PRK00389 143 AMIAVQGPKAREKLQKLTDADLSE--LKPFF--GAQGAEVGGGDVLVArtgYTGEDGFEIYLPAEDAEALWDALLEAG-- 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 705 egIDNFGTYAMNALRLEKAFRAWGSEMNCDTNPLEAGLESFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLaTDDVDP 784
Cdd:PRK00389 217 --VKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEEKRDFIGREALEAQKEAGVERKLVGLEL-EERGIP 293

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 329663159 785 EGNESIWYDGKVVGNTTSGSYSYRIQKSLAFAYVPVElskVGQQVEVELLGKNYPAVVIQEPLV 848
Cdd:PRK00389 294 RHGYPVLADGEEIGEVTSGTFSPTLGKSIALAYVPAG---VGDEVEVEIRGKQVPAKVVKPPFV 354
FAO_M pfam16350
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ...
 419-472 1.67e-13

FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).


Pssm-ID: 465100  Cd Length: 56  Bit Score: 65.55  E-value: 1.67e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 329663159  419 EPPFDLIELDPNRYGK-WTTAEYTEAKARESYGFNNIVGYPKEERFAGRPtQRVS 472
Cdd:pfam16350   3 EPPIDLWECDIRRFGPhQNNREYLRERVAENYGEVYDIHHPNEEREAGRP-LRTS 56
solA PRK11259
N-methyl-L-tryptophan oxidase;
53-431 2.84e-11

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 66.01  E-value: 2.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  53 VIIGGGCVGVSLAYHLAKAGmKDVVLLEKSEL--TAGS-------TWHAaglttYF-HPGinlkkihyY------SIKLY 116
Cdd:PRK11259   7 IVIGLGSMGSAAGYYLARRG-LRVLGLDRFMPphQQGSshgdtriIRHA-----YGeGPA--------YvplvlrAQELW 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 117 EKLEEETGQVVgFHQPGSIRIAttPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLNMNKILAGLYNPGDGHIDPY 196
Cdd:PRK11259  73 RELERESGEPL-FVRTGVLNLG--PADSDFLANSIRSARQHGLPHEVLDAAEIRRRFPQFRLPDGYIALFEPDGGFLRPE 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 197 SLTMALAAGARKYGALLKYPAPVTSLKPRSDGTwDVETPHGSMRANRIVNAAGFWAREvgkMIG-LEHPLIPVQHQYIIT 275
Cdd:PRK11259 150 LAIKAHLRLAREAGAELLFNEPVTAIEADGDGV-TVTTADGTYEAKKLVVSAGAWVKD---LLPpLELPLTPVRQVLAWF 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 276 STIPEVKALKReLPVlrdlegsfYLRQERDGLLF-G-PYESQEKMKVqdswvtsgvppgfGKELF------ESDLDRIME 347
Cdd:PRK11259 226 QADGRYSEPNR-FPA--------FIWEVPDGDQYyGfPAENGPGLKI-------------GKHNGgqeitsPDERDRFVT 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 348 HVEAAMDLVPVLKK--ADIIRIVNGPI---TYSPDILPMVGPHQGVRNYWVAVGF-GYGIIHAGGVGKYLSDWILHREPP 421
Cdd:PRK11259 284 VAEDGAELRPFLRNylPGVGPCLRGAActyTNTPDEHFIIDTLPGHPNVLVASGCsGHGFKFASVLGEILADLAQDGTSD 363

                        410
                 ....*....|
gi 329663159 422 FDLIELDPNR 431
Cdd:PRK11259 364 FDLSPFSLSR 373
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 51-434 4.57e-10

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 62.54  E-value: 4.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159   51 ETVIIGGGCVGVSLAYHLAKAGMKdVVLLEKSEL--TAGS------TWHAAGLTTYFHPginlkkIHYYSIKLYEKLEEE 122
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKK-TLLLEQFDLphSRGSshgqsrIIRKAYPEDFYTP------MMLECYQLWAQLEKE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  123 TGQVVgFHQPGSIRIAttPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLNMNKILAGLYNPGDGHIDPYSLTMAL 202
Cdd:TIGR01377  75 AGTKL-HRQTGLLLLG--PKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRAL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  203 AAGARKYGALLKYPAPVTSLKPrSDGTWDVETPHGSMRANRIVNAAGFWAREVGKMIGLEHPLIP-----------VQHQ 271
Cdd:TIGR01377 152 QELAEAHGATVRDGTKVVEIEP-TELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPlrinvcywrekEPGS 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  272 YIITSTIPEVKALkrelpvlrDLEGSFYlrqerdGLLFGPYESQEKMKVQ-DSWV---TSGVPPGFGKElfesDLDRIME 347
Cdd:TIGR01377 231 YGVSQAFPCFLVL--------GLNPHIY------GLPSFEYPGLMKVYYHhGQQIdpdERDCPFGADIE----DVQILRK 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  348 HVEAAM-DLVPVLKKADIIRIVNgpitySPDILPMVGPHQGVRNYWVAVGF-GYGIIHAGGVGKYLSDWILHREPPFDLI 425
Cdd:TIGR01377 293 FVRDHLpGLNGEPKKGEVCMYTN-----TPDEHFVIDLHPKYDNVVIGAGFsGHGFKLAPVVGKILAELAMKLKPSYDLA 367


                  ....*....
gi 329663159  426 ELDPNRYGK 434
Cdd:TIGR01377 368 IFSLNRFAL 376
 
Name Accession Description Interval E-value
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 489-857 3.75e-119

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 365.94  E-value: 3.75e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 489 GWEQPHWFYkpgqdpgyrpsfhrtnwfEPVGSEYQQVMQRVGVIDLSPFGKFNIKGQDSIRLLDHLFANVIPK--VGFTN 566
Cdd:COG0404   25 GWEMPVQYP------------------GGVIAEHLAVREAVGLFDVSHMGKIEVTGPDAAAFLDRLVTNDVSKlkPGRAR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 567 ISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEEeAIKGGYDVEIKNITDELGVLGVAGPYSRKVLQKLTS 646
Cdd:COG0404   87 YTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEE-HLPPDFDVTITDVTDDWALLAVQGPKAREVLAKLTD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 647 EDLSDnvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSAALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRA 726
Cdd:COG0404  166 ADLSA--LPFMSFREGTVAGVPVRVSRTGYTGEDGFEIYVPAEDAEALWDALLEAGEEFGVKPCGLGARDTLRLEAGYPL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 727 WGSEMNCDTNPLEAGLESFVKLNKPaDFIGKQALKQIKAKGLKRRLVCLTLaTDDVDPEGNESIWYDGKVVGNTTSGSYS 806
Cdd:COG0404  244 YGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL-DGRGVPRAGAPVLADGEVVGEVTSGTFS 321

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 329663159 807 YRIQKSLAFAYVPVELSKVGQQVEVELLGKNYPAVVIQEPLVltEPTRSRL 857
Cdd:COG0404  322 PTLGKSIALAYVPAGLARPGTELEVEIRGKRVPAEVVKPPFY--DPEGERL 370
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
49-431 4.55e-91

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 292.19  E-value: 4.55e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAGSTWHAAGL--TTYFHPGIN-LKKIHYYSIKLYEKLEEETGQ 125
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQlrPGLAALADRaLVRLAREALDLWRELAAELGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 126 VVGFHQPGSIRIATTPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLNMNKILAGLYNPGDGHIDPYSLTMALAAG 205
Cdd:COG0665   81 DCDFRRTGVLYLARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 206 ARKYGALLKYPAPVTSLKPRSDGTWDVETPHGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYIITSTIPEvkalK 285
Cdd:COG0665  161 ARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPD----L 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 286 RELPVLRDleGSFYLRQERDG-LLFGPYESqekmkvqdswvtsgvppgFGKELFESDLDRIMEHVEAAMDLVPVLKKADI 364
Cdd:COG0665  237 PLRPVLDD--TGVYLRPTADGrLLVGGTAE------------------PAGFDRAPTPERLEALLRRLRRLFPALADAEI 296

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 329663159 365 IRIVNGPITYSPDILPMVGPHQGVRNYWVAVGF-GYGIIHAGGVGKYLSDWILHREPPFDLIELDPNR 431
Cdd:COG0665  297 VRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHgGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
GCV_T pfam01571
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ...
 488-745 8.55e-68

Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.


Pssm-ID: 460255  Cd Length: 254  Bit Score: 225.93  E-value: 8.55e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  488 SGWEQPHWFYKPGQDpgyrpsfhrtnwfepvgSEYQQVMQRVGVIDLSPFGKFNIKGQDSIRLLDHLFANVI--PKVGFT 565
Cdd:pfam01571  15 AGWEMPVQYGSNGIL-----------------AEHRAVREAAGLFDVSHMGKIEVSGPDAAAFLQRLTTNDVskLKPGRA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  566 NISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEEEAikGGYDVEIKNITDELGVLGVAGPYSRKVLQKLT 645
Cdd:pfam01571  78 TYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHA--EKLDVVVVDVTDDYALLALQGPKAREVLEKLT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  646 SEDLSDNvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSAALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFR 725
Cdd:pfam01571 156 DGDLLEA-LPFFSFREIEIGGVPVRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELGLRPAGLGARDSLRLEAGLP 234

                         250       260
                  ....*....|....*....|
gi 329663159  726 AWGSEMNCDTNPLEAGLESF 745
Cdd:pfam01571 235 LYGHDLDEETTPLEAGLGWA 254
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 53-414 3.62e-65

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 221.89  E-value: 3.62e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159   53 VIIGGGCVGVSLAYHLAKAGMkDVVLLEK-SELTAGSTWHAAGLttyFHPGI------NLKKIHYYSIKLYEKLEEETGQ 125
Cdd:pfam01266   3 VVIGGGIVGLSTAYELARRGL-SVTLLERgDDPGSGASGRNAGL---IHPGLrylepsELARLALEALDLWEELEEELGI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  126 VVGFHQPGSIRIATTPVRvDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLnmNKILAGLYNPGDGHIDPYSLTMALAAG 205
Cdd:pfam01266  79 DCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLL--PGLRGGLFYPDGGHVDPARLLRALARA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  206 ARKYGALLKYPAPVTSLKpRSDGTWDVETPHgsmRANRIVNAAGFWAREVGkMIGLEHPLIPVQHQYIITSTIPEvKALK 285
Cdd:pfam01266 156 AEALGVRIIEGTEVTGIE-EEGGVWGVVTTG---EADAVVNAAGAWADLLA-LPGLRLPVRPVRGQVLVLEPLPE-ALLI 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  286 RELPVLRDLEGSFYLRQERDG-LLFGPYEsqekmkvqdswvtsgvpPGFGKELFESDLDRIMEHVEAAMDLVPVLkkADI 364
Cdd:pfam01266 230 LPVPITVDPGRGVYLRPRADGrLLLGGTD-----------------EEDGFDDPTPDPEEIEELLEAARRLFPAL--ADI 290

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 329663159  365 IRIVNGPITYsPDILPMVGPHqGVRNYWVAVGF-GYGIIHAGGVGKYLSDW 414
Cdd:pfam01266 291 ERAWAGLRPL-PDGLPIIGRP-GSPGLYLATGHgGHGLTLAPGIGKLLAEL 339
gcvT PRK00389
glycine cleavage system aminomethyltransferase GcvT;
474-848 7.64e-64

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 234742 [Multi-domain]  Cd Length: 359  Bit Score: 218.83  E-value: 7.64e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 474 LYET-LESKCSMGFHSGWEQPHWFykpgqdpgyrpsfhrtnwfepvGS---EYQQVMQRVGVIDLSPFGKFNIKGQDSIR 549
Cdd:PRK00389   7 LYDLhVALGAKMVDFGGWEMPVQY----------------------GSiieEHHAVRTDAGLFDVSHMGEVDVTGPDALA 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 550 LLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEEEAIkgGYDVEIKNITDEL 627
Cdd:PRK00389  65 FLQYLLANDVSKlkPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVVNAANREKDLAWIKSHAA--GFGVEVTDRSDDL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 628 GVLGVAGPYSRKVLQKLTSEDLSDnvFKFLQtkSLKVSNIPVTAIRIS---YTGELGWELYHRREDSAALYDAIMNAGqe 704
Cdd:PRK00389 143 AMIAVQGPKAREKLQKLTDADLSE--LKPFF--GAQGAEVGGGDVLVArtgYTGEDGFEIYLPAEDAEALWDALLEAG-- 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 705 egIDNFGTYAMNALRLEKAFRAWGSEMNCDTNPLEAGLESFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLaTDDVDP 784
Cdd:PRK00389 217 --VKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEEKRDFIGREALEAQKEAGVERKLVGLEL-EERGIP 293

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 329663159 785 EGNESIWYDGKVVGNTTSGSYSYRIQKSLAFAYVPVElskVGQQVEVELLGKNYPAVVIQEPLV 848
Cdd:PRK00389 294 RHGYPVLADGEEIGEVTSGTFSPTLGKSIALAYVPAG---VGDEVEVEIRGKQVPAKVVKPPFV 354
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
48-370 1.88e-35

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 139.90  E-value: 1.88e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEK-SELTAGSTWHAAGLttyFHPGINLKKihyYSIK---------LYE 117
Cdd:COG0579    3 EMYDVVIIGAGIVGLALARELSRYEDLKVLVLEKeDDVAQESSGNNSGV---IHAGLYYTP---GSLKarlcvegneLFY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 118 KLEEETGqvVGFHQPGSIRIATTPvrvDEFKYqmTRTRWHATEQY------IIEPEKIQEMFPLLNMNKIlAGLYNPGDG 191
Cdd:COG0579   77 ELCRELG--IPFKRCGKLVVATGE---EEVAF--LEKLYERGKANgvpgleILDREELRELEPLLSDEGV-AALYSPSTG 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 192 HIDPYSLTMALAAGARKYGALLKYPAPVTSLKPRSDGtWDVETPHGSMRANRIVNAAGFWAREVGKMIGLEHP--LIPVQ 269
Cdd:COG0579  149 IVDPGALTRALAENAEANGVELLLNTEVTGIEREGDG-WEVTTNGGTIRARFVINAAGLYADRLAQMAGIGKDfgIFPVK 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 270 HQYIITS-----------TIPEVKAlkrelP-----VLRDLEGSfylrqerdgLLFGPYeSQEKMKVQDSW---VTSGVP 330
Cdd:COG0579  228 GEYLVLDkpaelvnakvyPVPDPGA-----PflgvhLTRTIDGN---------LLFGPN-AVFVPKKEDSLldlFESLRF 292

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 329663159 331 PGFGKELFESDLDRIMEHV---------EAAMDLVPVLKKADIIRIVNG 370
Cdd:COG0579  293 PNFWPMLAKNLLTKYLESVtslskeaflEALRKYVPELPDEDLIPAFAG 341
PLN02319 PLN02319
aminomethyltransferase
 533-854 1.06e-31

aminomethyltransferase


Pssm-ID: 177953 [Multi-domain]  Cd Length: 404  Bit Score: 128.30  E-value: 1.06e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 533 DLSPFGKFNIKGQDSIRLLDHLFANVIP--KVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLVTGSGSELHDLRWIEE- 609
Cdd:PLN02319  79 DVSHMCGLSLKGKDAIPFLETLVVADIAglKDGTGTLSVFTNEKGGIIDDTVITKVTDDHIYLVVNAGCRDKDLAHIEEh 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 610 -EAIKG-GYDVEIkNITDELGVLGVAGPYSRKVLQKLTSEDLSDnvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHR 687
Cdd:PLN02319 159 mKAFKAkGGDVSW-HVHDERSLLALQGPLAAPVLQHLTKEDLSK--MYFGDFRITDINGADCFLTRTGYTGEDGFEISVP 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 688 REDSAALYDAIMnAGQEEGIDNFGTYAMNALRLEKAFRAWGSEMNCDTNPLEAGLESFVKLNKPA--DFIGKQALKQIKA 765
Cdd:PLN02319 236 SEHAVDLAKALL-EKSEGKVRLTGLGARDSLRLEAGLCLYGNDLEEHITPVEAGLAWTIGKRRRAegGFLGADVILKQLK 314

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 766 KGLKRRLVCLTlATDDVDPEGNESIWYDGKVVGNTTSGSYSYRIQKSLAFAYVPVELSKVGQQVEVELLGKNYPAVVIQE 845
Cdd:PLN02319 315 EGVSRRRVGFI-SSGAPARSHSEILDESGEKIGEVTSGGFSPCLKKNIAMGYVKSGFHKAGTEVKVEVRGKMYDAVVTKM 393


                 ....*....
gi 329663159 846 PLVltePTR 854
Cdd:PLN02319 394 PFV---PTK 399
GCV_T_C pfam08669
Glycine cleavage T-protein C-terminal barrel domain; This is a family of glycine cleavage ...
 770-848 6.85e-27

Glycine cleavage T-protein C-terminal barrel domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.


Pssm-ID: 462554 [Multi-domain]  Cd Length: 80  Bit Score: 104.48  E-value: 6.85e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 329663159  770 RRLVCLTLATDDVDPEGNESIWYDGKVVGNTTSGSYSYRIQKSLAFAYVPVELSKVGQQVEVELLGKNYPAVVIQEPLV 848
Cdd:pfam08669   1 RRLVGLELDDGDPLLRGGEPVLRDGEVVGYVTSGAYSPTLGKSIALAYVDAELAKPGTEVEVEIRGKRVPATVVKLPFY 79
gcvT PRK13579
glycine cleavage system aminomethyltransferase GcvT;
530-848 8.87e-20

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 237435 [Multi-domain]  Cd Length: 370  Bit Score: 92.32  E-value: 8.87e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 530 GVIDLSPFGKFNIKGQDSIRLLDHLFAN--VIPKVGFTNISHMLTPKGRVYAELTVSHQSpGEFLLVTGSGSELHDLRWI 607
Cdd:PRK13579  53 GLFDVSHMGQIEVSGKDAAAALERLVPVdiLALKEGRQRYTFFTNEQGGILDDLMVTNLG-DHLFLVVNAACKDADIAHL 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 608 EEEAikgGYDVEIKNITDElGVLGVAGPYSRKVLQKLtseDLSDNVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHR 687
Cdd:PRK13579 132 REHL---SDECEVNPLDDR-ALLALQGPEAEAVLADL---GPPVAALRFMDGFEPRLHGVDCFVSRSGYTGEDGFEISVP 204

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 688 REDSAALYDAIMNAGQEEGIdnfGTYAMNALRLEKAFRAWGSEMNCDTNPLEAGLESFVKLNK--PADFIGKQALKQIKA 765
Cdd:PRK13579 205 ADAAEALAEALLADPRVEPI---GLGARDSLRLEAGLCLYGHDIDTTTTPVEAALEWAIQKARreAGGFPGAKAILAALA 281

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 766 KGLKRRLVCLTLATDDVDPEGNESIWYDGKVVGNTTSGSYSYRIQKSLAFAYVPVELSKVGQQVEVELLGKNYPAVVIQE 845
Cdd:PRK13579 282 KGASRRRVGLKPEGRAPVREGAPLFDDAGTEIGTVTSGGFGPSVGGPVAMGYVPASLAAPGTAVFAEVRGKRLPVTVHAL 361


                 ...
gi 329663159 846 PLV 848
Cdd:PRK13579 362 PFV 364
dmdA PRK12486
dimethylsulfoniopropionate demethylase;
515-832 4.09e-19

dimethylsulfoniopropionate demethylase;


Pssm-ID: 237113 [Multi-domain]  Cd Length: 368  Bit Score: 90.20  E-value: 4.09e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 515 FEPVGSEYQQVMQRVGVIDLSPFGKFNIKGQDSIRLLdhlfanvipkvgftnisHMLTPKgrvyaelTVSHQSPGEFL-- 592
Cdd:PRK12486  40 FESVEDDYAHLKEHVQVWDVAVERQVEIRGPDAARLV-----------------QMLTPR-------DLRGMKPGQCYyv 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 593 -LVTGSGSELHD--------------------LRWIEEEAIKGGYDVEIknitDELGV--LGVAGPYSRKVLQKLTSEDL 649
Cdd:PRK12486  96 pIVDETGGMLNDpvalklaedrwwisiadsdlLLWVKGLANGRKLDVLV----VEPDVspLAVQGPKADALMARVFGEAI 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 650 SDnvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSAA-LYDAIMNAGQEEgidNFGTYAMNAL-RLEKAFRAW 727
Cdd:PRK12486 172 RD--LRFFRFGYFDFEGTDLVIARSGYSKQGGFEIYVEGSDLGMpLWDALFEAGKDL---NVRAGCPNLIeRIEGGLLSY 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 728 GSEMNCDTNPLEAGLESFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWY-DGKVVGNTTSGSYS 806
Cdd:PRK12486 247 GNDMTRDNTPHECGLGRFCNTQTDIGCIGKDALLRVAKEGPQKQIRGIKIGGERIPPCDRAWPLLaGDNRVGQVTSAAYS 326

                        330       340
                 ....*....|....*....|....*.
gi 329663159 807 YRIQKSLAFAYVPVELSKVGQQVEVE 832
Cdd:PRK12486 327 PDFQTNVAIGMVRMTHWDPGTGLEVE 352
FAO_M pfam16350
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ...
 419-472 1.67e-13

FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).


Pssm-ID: 465100  Cd Length: 56  Bit Score: 65.55  E-value: 1.67e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 329663159  419 EPPFDLIELDPNRYGK-WTTAEYTEAKARESYGFNNIVGYPKEERFAGRPtQRVS 472
Cdd:pfam16350   3 EPPIDLWECDIRRFGPhQNNREYLRERVAENYGEVYDIHHPNEEREAGRP-LRTS 56
solA PRK11259
N-methyl-L-tryptophan oxidase;
53-431 2.84e-11

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 66.01  E-value: 2.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  53 VIIGGGCVGVSLAYHLAKAGmKDVVLLEKSEL--TAGS-------TWHAaglttYF-HPGinlkkihyY------SIKLY 116
Cdd:PRK11259   7 IVIGLGSMGSAAGYYLARRG-LRVLGLDRFMPphQQGSshgdtriIRHA-----YGeGPA--------YvplvlrAQELW 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 117 EKLEEETGQVVgFHQPGSIRIAttPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLNMNKILAGLYNPGDGHIDPY 196
Cdd:PRK11259  73 RELERESGEPL-FVRTGVLNLG--PADSDFLANSIRSARQHGLPHEVLDAAEIRRRFPQFRLPDGYIALFEPDGGFLRPE 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 197 SLTMALAAGARKYGALLKYPAPVTSLKPRSDGTwDVETPHGSMRANRIVNAAGFWAREvgkMIG-LEHPLIPVQHQYIIT 275
Cdd:PRK11259 150 LAIKAHLRLAREAGAELLFNEPVTAIEADGDGV-TVTTADGTYEAKKLVVSAGAWVKD---LLPpLELPLTPVRQVLAWF 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 276 STIPEVKALKReLPVlrdlegsfYLRQERDGLLF-G-PYESQEKMKVqdswvtsgvppgfGKELF------ESDLDRIME 347
Cdd:PRK11259 226 QADGRYSEPNR-FPA--------FIWEVPDGDQYyGfPAENGPGLKI-------------GKHNGgqeitsPDERDRFVT 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 348 HVEAAMDLVPVLKK--ADIIRIVNGPI---TYSPDILPMVGPHQGVRNYWVAVGF-GYGIIHAGGVGKYLSDWILHREPP 421
Cdd:PRK11259 284 VAEDGAELRPFLRNylPGVGPCLRGAActyTNTPDEHFIIDTLPGHPNVLVASGCsGHGFKFASVLGEILADLAQDGTSD 363

                        410
                 ....*....|
gi 329663159 422 FDLIELDPNR 431
Cdd:PRK11259 364 FDLSPFSLSR 373
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 51-434 4.57e-10

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 62.54  E-value: 4.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159   51 ETVIIGGGCVGVSLAYHLAKAGMKdVVLLEKSEL--TAGS------TWHAAGLTTYFHPginlkkIHYYSIKLYEKLEEE 122
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKK-TLLLEQFDLphSRGSshgqsrIIRKAYPEDFYTP------MMLECYQLWAQLEKE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  123 TGQVVgFHQPGSIRIAttPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPLLNMNKILAGLYNPGDGHIDPYSLTMAL 202
Cdd:TIGR01377  75 AGTKL-HRQTGLLLLG--PKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRAL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  203 AAGARKYGALLKYPAPVTSLKPrSDGTWDVETPHGSMRANRIVNAAGFWAREVGKMIGLEHPLIP-----------VQHQ 271
Cdd:TIGR01377 152 QELAEAHGATVRDGTKVVEIEP-TELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPlrinvcywrekEPGS 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  272 YIITSTIPEVKALkrelpvlrDLEGSFYlrqerdGLLFGPYESQEKMKVQ-DSWV---TSGVPPGFGKElfesDLDRIME 347
Cdd:TIGR01377 231 YGVSQAFPCFLVL--------GLNPHIY------GLPSFEYPGLMKVYYHhGQQIdpdERDCPFGADIE----DVQILRK 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  348 HVEAAM-DLVPVLKKADIIRIVNgpitySPDILPMVGPHQGVRNYWVAVGF-GYGIIHAGGVGKYLSDWILHREPPFDLI 425
Cdd:TIGR01377 293 FVRDHLpGLNGEPKKGEVCMYTN-----TPDEHFVIDLHPKYDNVVIGAGFsGHGFKLAPVVGKILAELAMKLKPSYDLA 367


                  ....*....
gi 329663159  426 ELDPNRYGK 434
Cdd:TIGR01377 368 IFSLNRFAL 376
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
53-262 5.43e-10

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 62.15  E-value: 5.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  53 VIIGGGCVGVSLAYHLAKA--GMKdVVLLEK-SELTAGSTWHAAGLttyFHPGInlkkihYY---SIK----------LY 116
Cdd:PRK11728   6 VIIGGGIVGLSTAMQLQERypGAR-IAVLEKeSGPARHQTGHNSGV---IHAGV------YYtpgSLKarfcrrgneaTK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 117 EKLE------EETGQVVgfhqpgsirIATTPVRVDEFKYQMTRTRWHATEQYIIEPEKIQEMFPllNMNKiLAGLYNPGD 190
Cdd:PRK11728  76 AFCDqhgipyEECGKLL---------VATSELELERMEALYERARANGIEVERLDAEELREREP--NIRG-LGAIFVPST 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 329663159 191 GHIDPYSLTMALAAGARKYGALLKYPAPVTSLKPRSDGTwDVETPHGSMRANRIVNAAGFWAREVGKMIGLE 262
Cdd:PRK11728 144 GIVDYRAVAEAMAELIQARGGEIRLGAEVTALDEHANGV-VVRTTQGEYEARTLINCAGLMSDRLAKMAGLE 214
PRK00711 PRK00711
D-amino acid dehydrogenase;
53-432 4.06e-09

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 59.81  E-value: 4.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  53 VIIGGGCVGVSLAYHLAKAGMKDVVL-------LEKSELTAG-------STWHAaglttyfhPGINLKKI---------- 108
Cdd:PRK00711   4 VVLGSGVIGVTSAWYLAQAGHEVTVIdrqpgpaLETSFANAGqispgyaAPWAA--------PGVPLKAIkwlfqrhapl 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 109 ------------------------HY------------YSIKLYEKLEEETGQVVGFHQPGSIRIATTPVRVDEFKYQMT 152
Cdd:PRK00711  76 airpdgdpfqlrwmwqmlrnctasRYavnksrmvrlaeYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 153 RTRWHATEQYIIEPEKIQEMFPLLN--MNKILAGLYNPGDGHIDPYSLTMALAAGARKYGALLKYPAPVTSLKPRSDGTW 230
Cdd:PRK00711 156 VLEEAGVPYELLDRDELAAVEPALAgvRHKLVGGLRLPNDETGDCQLFTQRLAAMAEQLGVKFRFNTPVDGLLVEGGRIT 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 231 DVETPHGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQhQYIITSTI-PEVKAlkrelPV------------------L 291
Cdd:PRK00711 236 GVQTGGGVITADAYVVALGSYSTALLKPLGVDIPVYPLK-GYSLTVPItDEDRA-----PVstvldetykiaitrfddrI 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 292 R-----DLEG-SFYLRQERDGLLfgpyesqeKMKVQDswvtsgvppgfgkeLFESDLDrimehveaamdlvpvLKKADI- 364
Cdd:PRK00711 310 RvggmaEIVGfDLRLDPARRETL--------EMVVRD--------------LFPGGGD---------------LSQATFw 352

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 329663159 365 --IRivngPITysPDILPMVGPHQgVRNYWVAVGFG-YGIIHAGGVGKYLSDWILHREPPFDLIELDPNRY 432
Cdd:PRK00711 353 tgLR----PMT--PDGTPIVGATR-YKNLWLNTGHGtLGWTMACGSGQLLADLISGRKPAIDADDLSVARY 416
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 160-275 3.65e-06

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 50.41  E-value: 3.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 160 EQYIIEPEKIQEMFPLLNmNKILAGLYNPGDGHIDPYSLTMALAAGARKYGALLKYPAPVTSLKPRSDG-----TWDVET 234
Cdd:PRK12409 162 ERRAVTPEEMRAIEPTLT-GEYYGGYYTPSDSTGDIHKFTTGLAAACARLGVQFRYGQEVTSIKTDGGGvvltvQPSAEH 240

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 329663159 235 PHGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQhQYIIT 275
Cdd:PRK12409 241 PSRTLEFDGVVVCAGVGSRALAAMLGDRVNVYPVK-GYSIT 280
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 46-94 2.24e-05

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 47.79  E-value: 2.24e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 329663159  46 WKDRAETVIIGGGCVGVSLAYHLAKAGmkDVVLLEKSELTAGSTWHAAG 94
Cdd:COG0029    1 ERLKTDVLVIGSGIAGLSAALKLAERG--RVTLLTKGELGESNTRWAQG 47
GlpA COG0578
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 166-264 3.81e-05

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440343 [Multi-domain]  Cd Length: 501  Bit Score: 47.05  E-value: 3.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 166 PEKIQEMFPLLNMNKILAG-LYnpGDGHIDPYSLTMALAAGARKYGAL-LKYpAPVTSLKPRSDGTW-----DVETphG- 237
Cdd:COG0578  107 RAEALALAPLLRPDGLRGGfEY--YDAQVDDARLVLELARTAAERGAVvLNY-TRVTGLLRDGGRVWgvtvrDRLT--Ge 181

                         90       100
                 ....*....|....*....|....*....
gi 329663159 238 --SMRANRIVNAAGFWAREVGKMIGLEHP 264
Cdd:COG0578  182 efTVRARVVVNATGPWVDELRALDGPKAP 210
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 51-91 6.23e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 46.39  E-value: 6.23e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 329663159  51 ETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSElTAGSTWH 91
Cdd:COG2072    8 DVVVIGAGQAGLAAAYHLRRAGI-DFVVLEKAD-DVGGTWR 46
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 52-84 8.15e-04

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 42.31  E-value: 8.15e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 329663159   52 TVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSEL 84
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGL-RVLLLEKKSF 34
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 49-83 9.14e-04

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 42.51  E-value: 9.14e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 329663159  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSE 83
Cdd:COG1232    1 MKRVAVIGGGIAGLTAAYRLAKAGH-EVTVLEASD 34
PRK07233 PRK07233
hypothetical protein; Provisional
 53-100 9.82e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 42.57  E-value: 9.82e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 329663159  53 VIIGGGCVGVSLAYHLAKAGmKDVVLLEKSELTAG--STWHAAGLT--TYFH 100
Cdd:PRK07233   3 AIVGGGIAGLAAAYRLAKRG-HEVTVFEADDQLGGlaASFEFGGLPieRFYH 53
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 53-295 1.12e-03

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 42.23  E-value: 1.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159  53 VIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAgstWHAAGLTtyfhpginlkkIHYYSIKLYEKLeeetgqvvGFHQp 132
Cdd:COG0654    7 LIVGGGPAGLALALALARAGI-RVTVVERAPPPR---PDGRGIA-----------LSPRSLELLRRL--------GLWD- 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 133 gsiRIATTPVRVDEFKYqmtRTRWHATEQYIIEPEKIQEMFPLlnmnkilaglynpgdgHIDPYSLTMALAAGARKYGAL 212
Cdd:COG0654   63 ---RLLARGAPIRGIRV---RDGSDGRVLARFDAAETGLPAGL----------------VVPRADLERALLEAARALGVE 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329663159 213 LKYPAPVTSLKPRSDGtWDVETPHGS-MRANRIVNAAGFWAReVGKMIGLEHPLIPVQHQYIITSTIPEVKA-LKRELPV 290
Cdd:COG0654  121 LRFGTEVTGLEQDADG-VTVTLADGRtLRADLVVGADGARSA-VRRLLGIGFTGRDYPQRALWAGVRTELRArLAAAGPR 198


                 ....*
gi 329663159 291 LRDLE 295
Cdd:COG0654  199 LGELL 203
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
54-101 4.16e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 36.36  E-value: 4.16e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 329663159   54 IIGGGCVGVSLAYHLAKAGmKDVVLLEKSELTAG--STWHAAGLT-----TYFHP 101
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRG-FRVLVLEKRDRLGGnaYSYRVPGYVfdygaHIFHG 54
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 53-94 9.79e-03

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 39.43  E-value: 9.79e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 329663159  53 VIIGGGCVGVSLAYHLAKAGMKdVVLLEKSELTAGSTWHAAG 94
Cdd:COG1053    7 VVVGSGGAGLRAALEAAEAGLK-VLVLEKVPPRGGHTAAAQG 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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