|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
16-326 |
3.68e-125 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 361.50 E-value: 3.68e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 16 KIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMvLELNASDD 95
Cdd:PRK00440 1 AMMEEIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYGEDWRENF-LELNASDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 96 RGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFG 175
Cdd:PRK00440 80 RGIDVIRNKIKEFARTAPVGGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 176 PLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWML 255
Cdd:PRK00440 160 PLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKEVTEEAVYKITGTARPEEIREMIELAL 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 332164786 256 NQDFTTAYRKLKTL---KGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAF 326
Cdd:PRK00440 240 NGDFTEAREKLRDLmidYGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEALLAKL 313
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
20-331 |
1.20e-88 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 268.52 E-value: 1.20e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 20 LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQL----YKDKefgsmVLELNASDD 95
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELlgpnYKEA-----VLELNASDD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 96 RGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRF 174
Cdd:PLN03025 76 RGIDVVRNKIKMFAQKKVTLPPGrHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRF 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 175 GPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWM 254
Cdd:PLN03025 156 SRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSGFGFVNQENVFKVCDQPHPLHVKNIVRNC 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 332164786 255 LNQDFTTAYRKLKTL--KGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRD 331
Cdd:PLN03025 236 LKGKFDDACDGLKQLydLGYSPTDIITTLFRVVKNYDMPEFLKLEYLREIGFAHMRICDGVGSLLQLSGLLAKLCLVRE 314
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
22-326 |
1.43e-72 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 227.95 E-value: 1.43e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 22 WVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKeFGSMVLELNASD------- 94
Cdd:PRK12402 5 WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDP-WENNFTEFNVADffdqgkk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 95 -----DRGIDIIRGPILSFASTRTIFKK-------------GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICN 156
Cdd:PRK12402 84 ylvedPRFAHFLGTDKRIRSSKIDNFKHvlkeyasyrplsaDYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 157 YLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVY 236
Cdd:PRK12402 164 QPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITMEAAY 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 237 TCTGH-PLKSDIANILDWMLNQDFTTAYRKLKTL---KGLALHDILTEIHLFVHRVDFPSSV-RIHllTKMADIEYRLSV 311
Cdd:PRK12402 244 EALGDvGTDEVIESLLDAAEAGDFTDARKTLDDLlidEGLSGGEVLEELLRVARSRYRGDNLaRLH--RLAADADARLTD 321
|
330
....*....|....*
gi 332164786 312 GTNEKIQLSSLIAAF 326
Cdd:PRK12402 322 GANDRIQLEALLAEL 336
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
67-326 |
1.69e-64 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 218.56 E-value: 1.69e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 67 TSTILACAKQLYKDKeFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFT 146
Cdd:PRK04132 580 TTAALALARELFGEN-WRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFS 658
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 147 ENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMA 226
Cdd:PRK04132 659 SNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAAL 738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 227 FGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRKLKTL---KGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMA 303
Cdd:PRK04132 739 DDKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREIllkQGLSGEDVLVQMHREVFNLPIDEPKKVELADKIG 818
|
250 260
....*....|....*....|...
gi 332164786 304 DIEYRLSVGTNEKIQLSSLIAAF 326
Cdd:PRK04132 819 EYNFRLVEGANEMIQLEALLAQF 841
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
37-327 |
1.17e-57 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 188.26 E-value: 1.17e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 37 HQDILSTIQKFINEDRLPH-LLLYGPPGTGKTSTILACAKQLYKDKEFGSM-----------------VLELNA---SDD 95
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLCENPEGGKacgqchsrlmaagnhpdLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 96 RGIDIIRGpILSFASTRTIFKkGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFG 175
Cdd:COG0470 81 IGIDQIRE-LGEFLSLTPLEG-GRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 176 PLTPELMVPRLehvvEEEKVDisEDGMKALVTLSSGDMRRALNILQStnMAFGKVTEETVYTCTGHP---------LKSD 246
Cdd:COG0470 159 PPSEEEALAWL----REEGVD--EDALEAILRLAGGDPRAAINLLQA--LAGRKELLEDLAALLSRDralelldalLKAE 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 247 IANILDWMLNQdfttayrklktlkglaLHDILteihlfvhRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAF 326
Cdd:COG0470 231 ALELLDWLLKW----------------LLDNL--------PLEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLAKL 286
|
.
gi 332164786 327 Q 327
Cdd:COG0470 287 G 287
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
22-261 |
3.17e-49 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 167.09 E-value: 3.17e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 22 WVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGP-PGTGKTSTILA-CAkqlykdkEFGSMVLELNASDDRgID 99
Cdd:PHA02544 11 WEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPsPGTGKTTVAKAlCN-------EVGAEVLFVNGSDCR-ID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 100 IIRGPILSFASTRTiFKKGFKLVILDEAD-AMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLT 178
Cdd:PHA02544 83 FVRNRLTRFASTVS-LTGGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVIDFGVPT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 179 PE-------LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQStNMAFGKVTEETVYTCTGhplkSDIANIL 251
Cdd:PHA02544 162 KEeqiemmkQMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQR-YASTGKIDAGILSEVTN----SDIDDVV 236
|
250
....*....|
gi 332164786 252 DWMLNQDFTT 261
Cdd:PHA02544 237 EALKAKDFKA 246
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
20-268 |
9.32e-44 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 156.62 E-value: 9.32e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 20 LPWVEKYRPQTLNDLISHQDILSTIQKFINE--DRLPH--LLLYGPPGTGKTSTILACAKqlykdkEFGSMVLELNASDD 95
Cdd:PRK04195 2 MPWVEKYRPKTLSDVVGNEKAKEQLREWIESwlKGKPKkaLLLYGPPGVGKTSLAHALAN------DYGWEVIELNASDQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 96 RGIDIIRGPILSFASTRTIFKKGFKLVILDEADAM--TQDAQNAlrRVIEKFTENTRFCLIC---NYLSKIIPALQSRCT 170
Cdd:PRK04195 76 RTADVIERVAGEAATSGSLFGARRKLILLDEVDGIhgNEDRGGA--RAILELIKKAKQPIILtanDPYDPSLRELRNACL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 171 RFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANI 250
Cdd:PRK04195 154 MIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGKLTLEDVKTLGRRDREESIFDA 233
|
250
....*....|....*...
gi 332164786 251 LDWMLNqdfTTAYRKLKT 268
Cdd:PRK04195 234 LDAVFK---ARNADQALE 248
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
21-294 |
5.65e-35 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 133.03 E-value: 5.65e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 21 PWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTST--ILA----------------CAKQLYKDK 81
Cdd:PRK14953 5 PFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFaGPRGTGKTTIarILAkvlnclnpqegepcgkCENCVEIDK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 82 -EFGSMVlELNASDDRGIDIIRGpiLSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSK 160
Cdd:PRK14953 85 gSFPDLI-EIDAASNRGIDDIRA--LRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 161 IIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCT 239
Cdd:PRK14953 162 IPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLdQASTYGEGKVTIKVVEEFL 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 332164786 240 GHPLKSDIANILDWMLNQDFTTAYRKLKTL--KGLALH----DILTEIH--LFVHRVDFPSSV 294
Cdd:PRK14953 242 GIVSQESVRKFLNLLLESDVDEAIKFLRTLeeKGYNLNkfwkQLEEEIRniLLNKSLKNPEEV 304
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
28-288 |
2.97e-32 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 122.99 E-value: 2.97e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 28 PQTLNDLISHQDILSTIQKFINEDRLPH-LLLYGPPGTGKTST--ILA----CAKQLYKD-----------KEFGSM-VL 88
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLarILAkalnCENGPTGEpcgecescraiAAGSHPdVI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 89 EL--NASDdRGIDIIRGPI--LSFASTRTifkkGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPA 164
Cdd:COG2812 86 EIdaEASN-IGVDDIRELIekVSYAPVEG----RYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 165 LQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQStNMAFGKVteetvytctghPLK 244
Cdd:COG2812 161 ILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ-AIAFGLL-----------DRR 228
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 332164786 245 SDIANILDWMLNQDFTTAYRKLKTL--KGLALHDILTEIHLFVHRV 288
Cdd:COG2812 229 ELLLDLLEALLAGDVAALLALAEELakRGRDLKRFLDDLLSLLRDL 274
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
24-241 |
9.02e-30 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 117.49 E-value: 9.02e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 24 EKYRPQTLNDLISHQDIL---STIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLykDKEFgsmvLELNASDDrGIDI 100
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGAT--DAPF----EALSAVTS-GVKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 101 IRGpILSFASTRTIFKKGFkLVILDEADAMTQDAQNALRRVIEKF--------TENTRFclicnylsKIIPALQSRCTRF 172
Cdd:PRK13342 77 LRE-VIEEARQRRSAGRRT-ILFIDEIHRFNKAQQDALLPHVEDGtitligatTENPSF--------EVNPALLSRAQVF 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 332164786 173 RFGPLTPELMVPRLEHVVEEEK---VDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGH 241
Cdd:PRK13342 147 ELKPLSEEDIEQLLKRALEDKErglVELDDEALDALARLANGDARRALNLLELAALGVDSITLELLEEALQK 218
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
242-325 |
2.37e-28 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 105.25 E-value: 2.37e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 242 PLKSDIANILDWMLNQDFTTAY---RKLKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQ 318
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYkkvRELLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*..
gi 332164786 319 LSSLIAA 325
Cdd:pfam08542 81 LSALLAA 87
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
20-270 |
8.68e-28 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 114.14 E-value: 8.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 20 LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTST--ILACA------KQLYK---------DK 81
Cdd:PRK07133 6 KALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFsGPRGTGKTSVakIFANAlncshkTDLLEpcqecienvNN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 82 EFGsmVLELNASDDRGIDIIRGPILSFASTRTIFKkgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKI 161
Cdd:PRK07133 86 SLD--IIEMDAASNNGVDEIRELIENVKNLPTQSK--YKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 162 IPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTG 240
Cdd:PRK07133 162 PLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAeQVSIFGNNKITLKNVEELFG 241
|
250 260 270
....*....|....*....|....*....|
gi 332164786 241 HPLKSDIANILDWMLNQDFTTAYRKLKTLK 270
Cdd:PRK07133 242 LVSNENLINLLNLLYSKDIKEVLNILNQIK 271
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
25-273 |
1.95e-26 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 109.90 E-value: 1.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTST--ILA----CAKQLYKDKEFG--SM--------- 86
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFtGPRGVGKTSTarILAkavnCTTNDPKGRPCGtcEMcraiaegsa 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 --VLELNASDDRGIDIIRGPILSFASTRTIFKKgfKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPA 164
Cdd:PRK14950 89 vdVIEMDAASHTSVDDAREIIERVQFRPALARY--KVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPAT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 165 LQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTnMAF--GKVTEETVYTCTGHP 242
Cdd:PRK14950 167 ILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQL-ATTygGEISLSQVQSLLGIS 245
|
250 260 270
....*....|....*....|....*....|.
gi 332164786 243 LKSDIANILDWMLNQDFTTAyrkLKTLKGLA 273
Cdd:PRK14950 246 GDEEVKALAEALLAKDLKAA---LRTLNAVA 273
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
25-240 |
4.91e-26 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 107.93 E-value: 4.91e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLYKDKEFGSM----------------- 86
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFaGPRGTGKTTVARILAKSLNCENRKGVEpcnecracrsidegtfm 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 -VLELNASDDRGIDIIRgPILSFASTRTIFKKgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPAL 165
Cdd:PRK14962 87 dVIELDAASNRGIDEIR-KIRDAVGYRPMEGK-YKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 332164786 166 QSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTG 240
Cdd:PRK14962 165 ISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLeQVWKFSEGKITLETVHEALG 240
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
25-335 |
7.63e-25 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 105.18 E-value: 7.63e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPH-LLLYGPPGTGKTSTILACAKQLYKDK----------------EFGSMV 87
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTTIARILAKSLNCENaqhgepcgvcqsctqiDAGRYV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 88 --LELNASDDRGIDIIRgPILSFASTRTIFKKgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPAL 165
Cdd:PRK08691 89 dlLEIDAASNTGIDNIR-EVLENAQYAPTAGK-YKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 166 QSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTGHPLK 244
Cdd:PRK08691 167 LSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLdQAIALGSGKVAENDVRQMIGAVDK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 245 SDIANILDWMLNQDFTTAYRKLKTL--KGLALHDILTEIHLFVHRVDFPSSVRIHLLTK--MADIEYRLSVG-TNEKIQL 319
Cdd:PRK08691 247 QYLYELLTGIINQDGAALLAKAQEMaaCAVGFDNALGELAILLQQLALIQAVPSALAHDdpDSDILHRLAQTiSGEQIQL 326
|
330
....*....|....*.
gi 332164786 320 SSLIAAfQVTRDLIVA 335
Cdd:PRK08691 327 YYQIAV-HGKRDLSLA 341
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
35-176 |
2.55e-22 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 91.44 E-value: 2.55e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 35 ISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLykdKEFGSMVLELNASDDRGIDIIRGPILSFASTRTI 114
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANEL---FRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLF 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 332164786 115 FKK---GFKLVILDEADAMTQDAQNALRRVIEKF------TENTRFCLICNY--LSKIIPALQSRC-TRFRFGP 176
Cdd:cd00009 78 ELAekaKPGVLFIDEIDSLSRGAQNALLRVLETLndlridRENVRVIGATNRplLGDLDRALYDRLdIRIVIPL 151
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
25-330 |
2.85e-22 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 97.25 E-value: 2.85e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTST--ILA----CAKQlyKDKEF------------GS 85
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFsGPRGTGKTSAakIFAkavnCLNP--PDGEPcneceickaitnGS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 86 M--VLELNASDDRGIDIIRgPILS---FASTRTIFKkgfklV-ILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLS 159
Cdd:PRK05563 87 LmdVIEIDAASNNGVDEIR-DIRDkvkYAPSEAKYK-----VyIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 160 KIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTC 238
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILdQAISFGDGKVTYEDALEV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 239 TGHPLKSDIANILDWMLNQDFTTAYRklktlkglALHDILTE---IHLFVhrVDFPSSVRIHLLTKMADIEYRLSVGTNE 315
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALK--------ILEELLDEgkdPNRFI--EDLIYYLRDLLLVKTSPELEILDESTEN 310
|
330
....*....|....*
gi 332164786 316 KIQLSSLIAAFQVTR 330
Cdd:PRK05563 311 DELFKELSEKLDIER 325
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
27-220 |
3.58e-22 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 96.28 E-value: 3.58e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 27 RPQTLNDLISHQDIL---STIQKFINEDRLPHLLLYGPPGTGKTStiLA--CAKQLykDKEFgsmvLELNASDDrGIDII 101
Cdd:COG2256 20 RPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILWGPPGTGKTT--LArlIANAT--DAEF----VALSAVTS-GVKDI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 102 RGpILSFASTRTIFKKGFkLVILDEADAMTQDAQNALRRVIEK----F----TENTRFclicnylsKIIPALQSRCTRFR 173
Cdd:COG2256 91 RE-VIEEARERRAYGRRT-ILFVDEIHRFNKAQQDALLPHVEDgtitLigatTENPSF--------EVNSALLSRCRVFV 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 332164786 174 FGPLTPELMVPRLEHVVEEE-------KVDISEDGMKALVTLSSGDMRRALNIL 220
Cdd:COG2256 161 LKPLSEEDLEQLLERALADDerglggyKLELDDEALEALARLADGDARRALNAL 214
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
24-281 |
4.10e-22 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 97.22 E-value: 4.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 24 EKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQL----YKD--------------KEFG 84
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFsGPRGIGKTSIAKIFAKAInclnPKDgdccnscsvcesinTNQS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 85 SMVLELNASDDRGIDIIRGPILSFASTRTIFKKgfKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPA 164
Cdd:PRK05896 88 VDIVELDAASNNGVDEIRNIIDNINYLPTTFKY--KVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 165 LQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTGHPL 243
Cdd:PRK05896 166 IISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILdQLSTFKNSEIDIEDINKTFGLVD 245
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 332164786 244 KSDIANILDWMLNQDFTTAYRKLKTL--KGLALHDILTEI 281
Cdd:PRK05896 246 NNKKINLIELIQKNDIEELRNLINELesKGINFEAFCRDL 285
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
25-240 |
2.16e-21 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 94.81 E-value: 2.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLykDKEFGSM----------------- 86
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFtGARGVGKTSTARILAKAL--NCEQGLTaepcnvcppcveitegr 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 ---VLELNASDDRGIDIIRGpiLSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIP 163
Cdd:PRK14965 87 svdVFEIDGASNTGVDDIRE--LRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 332164786 164 ALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGK-VTEETVYTCTG 240
Cdd:PRK14965 165 TILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDaVGDDDVAELLG 242
|
|
| holB |
TIGR00678 |
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ... |
44-188 |
1.13e-20 |
|
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273213 [Multi-domain] Cd Length: 188 Bit Score: 88.07 E-value: 1.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 44 IQKFINEDRLPH-LLLYGPPGTGKTSTILACAKQLYKDKEFGS--------------------MVLELNAsDDRGIDIIR 102
Cdd:TIGR00678 4 LKRALEKGRLAHaYLFTGPEGVGKELLALALAKALLCEQRGGGepcgechscrlieagnhpdlHRLEPEG-QSIKVDQVR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 103 GpILSFASTRTIfKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELM 182
Cdd:TIGR00678 83 E-LVEFLSRTPQ-ESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160
|
....*.
gi 332164786 183 VPRLEH 188
Cdd:TIGR00678 161 LQWLIR 166
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
177-239 |
2.00e-20 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 83.35 E-value: 2.00e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 332164786 177 LTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCT 239
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGVITEEDVYEVA 63
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
25-269 |
3.48e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 91.00 E-value: 3.48e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLIShQDILSTI-QKFINEDRLPH-LLLYGPPGTGKTST------ILACAKQLYKD-----------KEFGS 85
Cdd:PRK14964 6 KYRPSSFKDLVG-QDVLVRIlRNAFTLNKIPQsILLVGASGVGKTTCariislCLNCSNGPTSDpcgtchncisiKNSNH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 86 M-VLELNASDDRGIDIIRgPILSFASTRTIFKKgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPA 164
Cdd:PRK14964 85 PdVIEIDAASNTSVDDIK-VILENSCYLPISSK-FKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 165 LQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTGHPL 243
Cdd:PRK14964 163 IISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLeQAAIYSNNKISEKSVRDLLGCVD 242
|
250 260
....*....|....*....|....*.
gi 332164786 244 KSDIANILDWMLNQDFTTAYRKLKTL 269
Cdd:PRK14964 243 KHILEDLVEAILLGDAQSALNVFREL 268
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
25-288 |
4.09e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 89.87 E-value: 4.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHL-LLYGPPGTGKTSTILACAKQLY----------------KDKEFGSM- 86
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLNcqngitsnpcrkciicKEIEKGLCl 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 -VLELNASDDRGIDIIRGPILSFASTRTifKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPAL 165
Cdd:PRK14961 89 dLIEIDAASRTKVEEMREILDNIYYSPS--KSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 166 QSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTGHPLK 244
Cdd:PRK14961 167 LSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLeHAINLGKGNINIKNVTDMLGLLNE 246
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 332164786 245 SDIANILDWMLNQDFTTAYRKLKTLK--GLALHDILTEIHLFVHRV 288
Cdd:PRK14961 247 KQSFLLTDALLKKDSKKTMLLLNKISsiGIEWENILIEMLRFLHHI 292
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
25-251 |
6.80e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 89.16 E-value: 6.80e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQL----YKDKE--FGSMVLELNASDDRG 97
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFcGPRGVGKTTCARILARKInqpgYDDPNedFSFNIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 98 IDIIRGPIlsfASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGP 176
Cdd:PRK14970 90 VDDIRNLI---DQVRIPPQTGkYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 177 LTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQ------STNMAFGKVTE-------ETVYTCTGHPL 243
Cdd:PRK14970 167 ITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDrvvtfcGKNITRQAVTEnlnildyDTYINVTDLIL 246
|
....*...
gi 332164786 244 KSDIANIL 251
Cdd:PRK14970 247 ENKIPELL 254
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
56-177 |
7.84e-19 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 81.10 E-value: 7.84e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 56 LLLYGPPGTGKTSTILACAkqlykdKEFGSMVLELNASDDRGIDIIRGPilsfASTRTIFKKGFKL----VILDEADAM- 130
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVA------KELGAPFIEISGSELVSKYVGESE----KRLRELFEAAKKLapcvIFIDEIDALa 70
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 131 ----------TQDAQNALRRVIEKFT---ENTRFCLICNYLSKIIPALQSRCTRFRFGPL 177
Cdd:pfam00004 71 gsrgsggdseSRRVVNQLLTELDGFTssnSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
24-242 |
9.07e-19 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 86.82 E-value: 9.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 24 EKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTST--ILA----CAKQLykDKEFGSM---------- 86
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFsGPRGVGKTTTarLIAmavnCSGED--PKPCGECesclavrrga 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 ---VLELNASDDRGIDIIRG--PILSFASTRTifkkGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKI 161
Cdd:PRK14963 84 hpdVLEIDAASNNSVEDVRDlrEKVLLAPLRG----GRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 162 IPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGH 241
Cdd:PRK14963 160 PPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALGTPVTRKQVEEALGL 239
|
.
gi 332164786 242 P 242
Cdd:PRK14963 240 P 240
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
17-221 |
2.43e-18 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 85.88 E-value: 2.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 17 IRNLPWVEKYRPQTLNDLISHQDILST---IQKFINEDRLPHLLLYGPPGTGKTStiLACAKQLYKDKEFGSM------V 87
Cdd:PRK13341 13 QSEAPLADRLRPRTLEEFVGQDHILGEgrlLRRAIKADRVGSLILYGPPGVGKTT--LARIIANHTRAHFSSLnavlagV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 88 LELNASDDRGIDiirgpILSFASTRTIfkkgfklVILDEADAMTQDAQNALRRVIEK--------FTENTRFclicnyls 159
Cdd:PRK13341 91 KDLRAEVDRAKE-----RLERHGKRTI-------LFIDEVHRFNKAQQDALLPWVENgtitligaTTENPYF-------- 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 332164786 160 KIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEE-------KVDISEDGMKALVTLSSGDMRRALNILQ 221
Cdd:PRK13341 151 EVNKALVSRSRLFRLKSLSDEDLHQLLKRALQDKergygdrKVDLEPEAEKHLVDVANGDARSLLNALE 219
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
25-284 |
3.65e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 79.31 E-value: 3.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLYKDKEFGSM----------------- 86
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFsGLRGSGKTSSARIFARALVCEQGPSSTpcdtciqcqsalenrhi 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 -VLELNASDDRGIDIIRGPI------LSFAStrtifkkgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLS 159
Cdd:PRK08451 87 dIIEMDAASNRGIDDIRELIeqtkykPSMAR--------FKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 160 KIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTC 238
Cdd:PRK08451 159 KLPATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLdQAIIYCKNAITESKVADM 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 332164786 239 TGHPLKSDIANILDWMLNQDFTTAYRKLKTLKGLALHDILTEIHLF 284
Cdd:PRK08451 239 LGLLDPSKLEDFFQAILNQDKEKLFELLKELEDYEAEMVLDEMMLF 284
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
25-237 |
4.22e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 78.66 E-value: 4.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLY-----------------KDKEFGSM 86
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFsGIRGTGKTTLARIFAKALNcqnptedqepcnqcascKEISSGTS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 --VLELNASDDRGIDIIR--GPILSFASTrtifKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKII 162
Cdd:PRK06305 90 ldVLEIDGASHRGIEDIRqiNETVLFTPS----KSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 163 PALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-------------QSTNMAFGK 229
Cdd:PRK06305 166 GTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYdyvvglfpksldpDSVAKALGL 245
|
....*...
gi 332164786 230 VTEETVYT 237
Cdd:PRK06305 246 LSQDSLYT 253
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
25-258 |
1.56e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 77.10 E-value: 1.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKT--STILA----------------CAKQLYKDKefGS 85
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFtGTRGVGKTtlARILAkslncetgvtatpcgvCSACLEIDS--GR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 86 MV--LELNASDDRGIDIIRgPILS---FASTRTifkkGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSK 160
Cdd:PRK14969 87 FVdlIEVDAASNTQVDAMR-ELLDnaqYAPTRG----RFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 161 IIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTnMAFG--KVTEETVYTC 238
Cdd:PRK14969 162 IPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQA-IAYGggTVNESEVRAM 240
|
250 260
....*....|....*....|
gi 332164786 239 TGHPLKSDIANILDWMLNQD 258
Cdd:PRK14969 241 LGAIDQDYLFALLEALLAQD 260
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
18-221 |
2.25e-15 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 76.92 E-value: 2.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 18 RNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH-----LLLYGPPGTGKTSTILACAKQL-YKDKEFGSMVLELN 91
Cdd:TIGR00602 70 GNEPWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKELgIQVQEWSNPTLPDF 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 92 ASDDRGIDIIRG-------------PILSFASTRTIFKKG------FKLVILDEADAMTQDAQNALRRVIE-KFTENTRF 151
Cdd:TIGR00602 150 QKNDHKVTLSLEscfsnfqsqievfSEFLLRATNKLQMLGddlmtdKKIILVEDLPNQFYRDTRALHEILRwKYVSIGRC 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 152 CLIC----------NYLSKIIPALQS---------RCTRFRFGPLTPELMVPRLEHVVEEEKVDISED---GMKALVTL- 208
Cdd:TIGR00602 230 PLVFiiteslegdnNQRRLLFPAETImnkeileepRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKikvPKKTSVELl 309
|
250
....*....|....*.
gi 332164786 209 ---SSGDMRRALNILQ 221
Cdd:TIGR00602 310 cqgCSGDIRSAINSLQ 325
|
|
| PRK07471 |
PRK07471 |
DNA polymerase III subunit delta'; Validated |
51-220 |
3.03e-15 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236022 [Multi-domain] Cd Length: 365 Bit Score: 75.84 E-value: 3.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 51 DRLPH-LLLYGPPGTGKTST-------ILA-----------------------CAKQLYKDKEFGSMVLELNASDDRG-- 97
Cdd:PRK07471 38 GRLHHaWLIGGPQGIGKATLayrmarfLLAtpppggdgavppptslaidpdhpVARRIAAGAHGGLLTLERSWNEKGKrl 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 98 -----IDIIRGPILSFASTRTIfkKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRF 172
Cdd:PRK07471 118 rtvitVDEVRELISFFGLTAAE--GGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKL 195
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 332164786 173 RFGPLTPELMVPRLehvvEEEKVDISEDGMKALVTLSSGDMRRALNIL 220
Cdd:PRK07471 196 RLRPLAPEDVIDAL----AAAGPDLPDDPRAALAALAEGSVGRALRLA 239
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
25-235 |
4.48e-15 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 76.07 E-value: 4.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKT--STILACAKQLYKDKEFGSMV-------------- 87
Cdd:PRK12323 9 KWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFtGTRGVGKTtlSRILAKSLNCTGADGEGGITaqpcgqcracteid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 88 -------LELNASDDRGIDIIrGPILSfastRTIFKKG---FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNY 157
Cdd:PRK12323 89 agrfvdyIEMDAASNRGVDEM-AQLLD----KAVYAPTagrFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTD 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 332164786 158 LSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETV 235
Cdd:PRK12323 164 PQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTdQAIAYSAGNVSEEAV 242
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
33-211 |
4.73e-15 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 74.68 E-value: 4.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 33 DLISHQDILSTIQKFINEDRLPHL-LLYGPPGTGKTstILAcakqlykdKEFGSMVLELNaSDDRGIDIIRGPILSFAS- 110
Cdd:PRK05564 5 TIIGHENIKNRIKNSIIKNRFSHAhIIVGEDGIGKS--LLA--------KEIALKILGKS-QQREYVDIIEFKPINKKSi 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 111 ----TRTIF----KKGF----KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLT 178
Cdd:PRK05564 74 gvddIRNIIeevnKKPYegdkKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLS 153
|
170 180 190
....*....|....*....|....*....|...
gi 332164786 179 PELMvprlEHVVEEEKVDISEDGMKALVTLSSG 211
Cdd:PRK05564 154 KEEI----EKFISYKYNDIKEEEKKSAIAFSDG 182
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
25-220 |
6.00e-15 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 75.69 E-value: 6.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTST--ILA----CAK--------------QLYKDKEf 83
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFsGPRGCGKTSSarILArslnCAQgptatpcgvcescvALAPNGP- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 84 GSM-VLELNASDDRGIDIIRG----PILSFASTRtifkkgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYL 158
Cdd:PRK14952 85 GSIdVVELDAASHGGVDDTRElrdrAFYAPAQSR------YRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 332164786 159 SKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDIsEDGMKALVTLS-SGDMRRALNIL 220
Cdd:PRK14952 159 EKVLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVV-DDAVYPLVIRAgGGSPRDTLSVL 220
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
28-221 |
1.10e-14 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 73.92 E-value: 1.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 28 PQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTS-------TIL-----ACAKQLYKDKEFGSMVLELNAS- 93
Cdd:PRK09112 19 PSENTRLFGHEEAEAFLAQAYREGKLHHALLFeGPEGIGKATlafhlanHILshpdpAEAPETLADPDPASPVWRQIAQg 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 94 ------------DDRG--------IDIIRGpILSFAStRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCL 153
Cdd:PRK09112 99 ahpnllhitrpfDEKTgkfktaitVDEIRR-VGHFLS-QTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFIL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 332164786 154 ICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVveEEKVDISEDGMKALVTLSSGDMRRALNILQ 221
Cdd:PRK09112 177 ISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHL--GSSQGSDGEITEALLQRSKGSVRKALLLLN 242
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
25-235 |
1.19e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 71.67 E-value: 1.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKT--STILA---------------------CakQLYKD 80
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFtGTRGVGKTtvSRILAkslncqgpdgqggitatpcgvC--QACRD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 81 KEFGSMV--LELNASDDRGIDIIRGpILSFAstrtIFK--KG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC 155
Cdd:PRK14951 87 IDSGRFVdyTELDAASNRGVDEVQQ-LLEQA----VYKpvQGrFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLAT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 156 NYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEET 234
Cdd:PRK14951 162 TDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTdQAIAFGSGQLQEAA 241
|
.
gi 332164786 235 V 235
Cdd:PRK14951 242 V 242
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
19-220 |
1.94e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 71.25 E-value: 1.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 19 NLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRL-PHLLLYGPPGTGKTST--ILA----CAK-----------QLYKD 80
Cdd:PRK14959 3 HASLTARYRPQTFAEVAGQETVKAILSRAAQENRVaPAYLFSGTRGVGKTTIarIFAkalnCETaptgepcntceQCRKV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 81 KEFGSM-VLELNASDDRGIDIIRGpiLSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLS 159
Cdd:PRK14959 83 TQGMHVdVVEIDGASNRGIDDAKR--LKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 332164786 160 KIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL 220
Cdd:PRK14959 161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLL 221
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
25-253 |
2.77e-13 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 70.57 E-value: 2.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTStilaCAKQLYK---------DKE----------FG 84
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFcGPRGVGKTT----CARIFAKtincqnltaDGEacnecescvaFN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 85 ---SM-VLELNASDDRGIDIIRGPILSFASTRTIFKkgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSK 160
Cdd:PRK14971 86 eqrSYnIHELDAASNNSVDDIRNLIEQVRIPPQIGK--YKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 161 IIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYtct 239
Cdd:PRK14971 164 ILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFdQVVSFTGGNITYKSVI--- 240
|
250
....*....|....
gi 332164786 240 ghplksDIANILDW 253
Cdd:PRK14971 241 ------ENLNILDY 248
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
25-216 |
6.03e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 69.41 E-value: 6.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLY----------------KDKEFGSM- 86
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFsGPRGVGKTSSARAFARCLNcvngptpmpcgecsscKSIDNDNSl 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 -VLELNASDDRGI-DI--IRGPILsF--ASTRtifkkgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSK 160
Cdd:PRK06647 89 dVIEIDGASNTSVqDVrqIKEEIM-FppASSR------YRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHK 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 332164786 161 IIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRA 216
Cdd:PRK06647 162 LPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDA 217
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
25-325 |
7.96e-13 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 69.31 E-value: 7.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLYKDKEFGSMVLELNAS-----DDRGI 98
Cdd:PRK14960 8 KYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFtGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATckavnEGRFI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 99 DIIRGPILS---FASTRTIF--------KKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQS 167
Cdd:PRK14960 88 DLIEIDAASrtkVEDTRELLdnvpyaptQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVIS 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 168 RCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTGHPLKSD 246
Cdd:PRK14960 168 RCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTdQAIAYGQGAVHHQDVKEMLGLIDRTI 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 247 IAN-ILDWMLNQ-----DFTTAYRKLKTLKGLALHDILTEIHlfvhrvdfpssvRIHLLTKMADIEYRLSVGTNEKI-QL 319
Cdd:PRK14960 248 IYDlILAVHQNQrekvsQLLLQFRYQALDVSLVLDQLISTLH------------ELALLQYLPELGLKYSEEINAKIlQL 315
|
....*.
gi 332164786 320 SSLIAA 325
Cdd:PRK14960 316 SKLISA 321
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
45-291 |
1.15e-12 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 67.81 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 45 QKFINEDRLPH-LLLYGPPGTGKTS-------TIL--------ACAK----QLYKDkefGS----MVLE-LNASDDRGID 99
Cdd:PRK05707 13 QQLAGRGRHPHaYLLHGPAGIGKRAlaerlaaALLceapqgggACGSckgcQLLRA---GShpdnFVLEpEEADKTIKVD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 100 IIRgPILSFAsTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTP 179
Cdd:PRK05707 90 QVR-ELVSFV-VQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSN 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 180 ELMVPRLEHVVEEEkvdiSEDGMKALVTLSSGDMRRALNiLQSTNMAF---------GKVTE------ETVYTCTGHPLK 244
Cdd:PRK05707 168 EESLQWLQQALPES----DERERIELLTLAGGSPLRALQ-LHEQGVREqrarvldgvKKLLKqqqsasQLAESWLKVPLL 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 332164786 245 SDIANILDW---MLNQDFTTAYRklktlkGLALHDILTEIHLFVHRVDFP 291
Cdd:PRK05707 243 LLFDWFCDWahdILRYQLTQDEE------GLGLADMRKVLQYLAQKSPQA 286
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
25-221 |
1.76e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 68.05 E-value: 1.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLIsHQDI-LSTIQKFINEDRLPH-LLLYGPPGTGKTST--ILA----------------CAKQLYKDKEFG 84
Cdd:PRK14956 11 KYRPQFFRDVI-HQDLaIGALQNALKSGKIGHaYIFFGPRGVGKTTIarILAkrlncenpignepcneCTSCLEITKGIS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 85 SMVLELNASDDRGIDIIRG--PILSFAStrtiFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKII 162
Cdd:PRK14956 90 SDVLEIDAASNRGIENIRElrDNVKFAP----MGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIP 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 332164786 163 PALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQ 221
Cdd:PRK14956 166 ETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFME 224
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
43-178 |
2.06e-12 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 64.15 E-value: 2.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 43 TIQKFINE---DRLPH-LLLYGPPGTGKTSTILACAKQLYKDKEFGSM----------VLELNASDDR---------GID 99
Cdd:pfam13177 5 AIQLLQNSlenGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDDLpcgqcrscrrIESGNHPDLViiepegqsiKID 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 332164786 100 IIRGpILSFASTRTIFKKgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLT 178
Cdd:pfam13177 85 QIRE-LQKEFSKSPYEGK-KKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPLS 161
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
25-220 |
8.60e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 65.68 E-value: 8.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAK-----QLYKDKEFGSMVLE--------- 89
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFsGLRGVGKTTAARVFAKavncqRMIDDADYLQEVTEpcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 90 ------------LNASDDRGIDIIRgpiLSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICN 156
Cdd:PRK14955 89 dfdagtslniseFDAASNNSVDDIR---LLRENVRYGPQKGrYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATT 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 332164786 157 YLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL 220
Cdd:PRK14955 166 ELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSIL 229
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
25-232 |
1.14e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 65.73 E-value: 1.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLY------------------------K 79
Cdd:PRK14954 9 KYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFsGLRGVGKTTAARVFAKAVNcqrmiddpvylqevtepcgecescR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 80 DKEFG-SM-VLELNASDDRGIDIIRgpiLSFASTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICN 156
Cdd:PRK14954 89 DFDAGtSLnISEFDAASNNSVDDIR---QLRENVRYGPQKGrYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATT 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 332164786 157 YLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTnMAFGKVTE 232
Cdd:PRK14954 166 ELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQV-IAFSVGSE 240
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
20-226 |
1.47e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 65.27 E-value: 1.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 20 LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH-LLLYGPPGTGKTST--ILA----CAKQLYKDKEFGSM------ 86
Cdd:PRK06645 9 IPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSarIIAkavnCSALITENTTIKTCeqctnc 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 ----------VLELNASDDRGIDIIRgPILSFASTRTIFKKgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICN 156
Cdd:PRK06645 89 isfnnhnhpdIIEIDAASKTSVDDIR-RIIESAEYKPLQGK-HKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATT 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 332164786 157 YLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMA 226
Cdd:PRK06645 167 EVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILdQAASMS 237
|
|
| PRK09111 |
PRK09111 |
DNA polymerase III subunits gamma and tau; Validated |
25-235 |
1.67e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236382 [Multi-domain] Cd Length: 598 Bit Score: 64.92 E-value: 1.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPH-LLLYGPPGTGKTST--ILAcaKQL-YKDKEfGSM-------------- 86
Cdd:PRK09111 17 KYRPQTFDDLIGQEAMVRTLTNAFETGRIAQaFMLTGVRGVGKTTTarILA--RALnYEGPD-GDGgptidlcgvgehcq 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 87 ---------VLELNASDDRGIDIIRGPILSF----ASTRtifkkgFKLVILDEADAMTQDAQNALRRVIE------KF-- 145
Cdd:PRK09111 94 aimegrhvdVLEMDAASHTGVDDIREIIESVryrpVSAR------YKVYIIDEVHMLSTAAFNALLKTLEeppphvKFif 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 146 --TEntrfclicnyLSKI-IPALqSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMkALVTLSS-GDMRRALNIL- 220
Cdd:PRK09111 168 atTE----------IRKVpVTVL-SRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEAL-ALIARAAeGSVRDGLSLLd 235
|
250
....*....|....*
gi 332164786 221 QSTNMAFGKVTEETV 235
Cdd:PRK09111 236 QAIAHGAGEVTAEAV 250
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
16-69 |
1.81e-11 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 65.25 E-value: 1.81e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 332164786 16 KIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTST 69
Cdd:PRK04132 3 KVLEKPWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLT 56
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
25-252 |
2.27e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 64.75 E-value: 2.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLYKDKEFGSmvlelNASDD----RGID 99
Cdd:PRK14958 9 KWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFtGTRGVGKTTISRILAKCLNCEKGVSA-----NPCNDcencREID 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 100 IIRGPIL---------SFASTRTIF--------KKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKII 162
Cdd:PRK14958 84 EGRFPDLfevdaasrtKVEDTRELLdnipyaptKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 163 PALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTnMAFGkvteetvytcTGHP 242
Cdd:PRK14958 164 VTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQS-IAYG----------NGKV 232
|
250
....*....|
gi 332164786 243 LKSDIANILD 252
Cdd:PRK14958 233 LIADVKTMLG 242
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
25-235 |
2.72e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 64.60 E-value: 2.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRL-PHLLLYGPPGTGKTST--ILA---------------CAK-QLYKDKEFGS 85
Cdd:PRK14948 9 KYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSarILAkslnclnsdkptpepCGKcELCRAIAAGN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 86 M--VLELNASDDRGIDIIRGPI--LSFAST--RtifkkgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLS 159
Cdd:PRK14948 89 AldVIEIDAASNTGVDNIRELIerAQFAPVqaR------WKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTDPQ 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 332164786 160 KIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETV 235
Cdd:PRK14948 163 RVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQLSLLPGPITPEAV 238
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
25-220 |
2.38e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 61.54 E-value: 2.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLI--SH-QDILSTIqkfINEDRLPHLLLY-GPPGTGKTST--ILA----CAK--------------QLYKD 80
Cdd:PRK07764 8 RYRPATFAEVIgqEHvTEPLSTA---LDSGRINHAYLFsGPRGCGKTSSarILArslnCVEgptstpcgecdscvALAPG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 81 KEfGSM-VLELNASDDRGIDIIR--------GPilsfASTRtifkkgFKLVILDEADAMTQDAQNALRRVIE------KF 145
Cdd:PRK07764 85 GP-GSLdVTEIDAASHGGVDDARelreraffAP----AESR------YKIFIIDEAHMVTPQGFNALLKIVEeppehlKF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 146 ----TENtrfclicnylSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDIsEDGMKALVTLS-SGDMRRALNIL 220
Cdd:PRK07764 154 ifatTEP----------DKVIGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPV-EPGVLPLVIRAgGGSVRDSLSVL 222
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
52-180 |
4.34e-10 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 57.38 E-value: 4.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 52 RLPHLLLYGPPGTGKTSTILACAKQLYKDKEFgsmVLELNASDDRGIDIIRGPILSFASTRT--------------IFKK 117
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGG---VIYIDGEDILEEVLDQLLLIIVGGKKAsgsgelrlrlalalARKL 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 332164786 118 GFKLVILDEADAMTQDAQNALRRVIEKFT--------ENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 180
Cdd:smart00382 78 KPDVLILDEITSLLDAEQEALLLLLEELRlllllkseKNLTVILTTNDEKDLGPALLRRRFDRRIVLLLIL 148
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
18-77 |
1.18e-09 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 56.89 E-value: 1.18e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 332164786 18 RNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH-----LLLYGPPGTGKTSTILACAKQL 77
Cdd:pfam03215 5 GGEQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL 69
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
25-235 |
1.57e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 59.09 E-value: 1.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQLY----------------KDKEFGSMV 87
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFtGTRGVGKTTLSRIFAKALNcetgvtsqpcgvcracREIDEGRFV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 88 --LELNASDDRGIDIIrGPILSFASTRTIFKKgFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPAL 165
Cdd:PRK07003 89 dyVEMDAASNRGVDEM-AALLERAVYAPVDAR-FKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTV 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 332164786 166 QSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETV 235
Cdd:PRK07003 167 LSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTdQAIAYSANEVTETAV 237
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
180-239 |
2.10e-09 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 53.24 E-value: 2.10e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 332164786 180 ELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAF--GKVTEETVYTCT 239
Cdd:cd18133 4 EQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGddGKISLDRVYQAV 65
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
25-320 |
1.24e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 56.24 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 25 KYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLY-GPPGTGKTSTILACAKQL-------------------YKDKEFG 84
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFtGTRGVGKTTLGRLLAKCLncktgvtaepcnkcencvaINNNSFI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 85 SMVlELNASDDRGIDIIRgPILSfaSTRTIFKKG-FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIP 163
Cdd:PRK14957 89 DLI-EIDAASRTGVEETK-EILD--NIQYMPSQGrYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 164 ALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTGHP 242
Cdd:PRK14957 165 TILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLdQAISFCGGELKQAQIKQMLGII 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 243 LKSDIANILDWMLNQDFTTAYRKLKTL-----KGLALHDILTE------IHLFVHRVDFPSSVRIHLLTKMAD---IE-- 306
Cdd:PRK14957 245 DSEEVYSIINAIIDNDPKAILPAIKNLaltesSADAVLDRIAEiwfaccIYSFTQSLDAVNDIDVDIINNILAkisIEqa 324
|
330
....*....|....*..
gi 332164786 307 ---YRLSVGTNEKIQLS 320
Cdd:PRK14957 325 hflYQLTITAKKDIALA 341
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
23-180 |
2.01e-08 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 55.30 E-value: 2.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 23 VEKYRPQTLNDLISHQDILSTIQKFINE----DRLP---------HLLLYGPPGTGKTSTILACAKQLykdkefGSMVLE 89
Cdd:COG0464 148 LLELREAILDDLGGLEEVKEELRELVALplkrPELReeyglppprGLLLYGPPGTGKTLLARALAGEL------GLPLIE 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 90 LNASDdrgidiIRGPIL--SFASTRTIFKK--GFKLVIL--DEADAM----TQDAQNALRRVIE---KFTENTRF--CLI 154
Cdd:COG0464 222 VDLSD------LVSKYVgeTEKNLREVFDKarGLAPCVLfiDEADALagkrGEVGDGVGRRVVNtllTEMEELRSdvVVI 295
|
170 180
....*....|....*....|....*....
gi 332164786 155 C--NYLSKIIPALQSRCTR-FRFGPLTPE 180
Cdd:COG0464 296 AatNRPDLLDPALLRRFDEiIFFPLPDAE 324
|
|
| PRK06964 |
PRK06964 |
DNA polymerase III subunit delta'; Validated |
51-187 |
6.78e-08 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 235898 [Multi-domain] Cd Length: 342 Bit Score: 53.23 E-value: 6.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 51 DRLPH-LLLYGPPGTGKTSTILACAKQL----------------------------YK--------DKEFGSMVLELNAS 93
Cdd:PRK06964 18 ARLPHaLLLHGQAGIGKLDFAQHLAQGLlcetpqpdgepcgtcaacnwfaqgnhpdYRivrpealaAEAPGAADEAKEAD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 94 DDRG------------IDIIRGpILSFASTRTiFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKI 161
Cdd:PRK06964 98 ADEGgkktkapskeikIEQVRA-LLDFCGVGT-HRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRL 175
|
170 180
....*....|....*....|....*.
gi 332164786 162 IPALQSRCTRFRFGPLTPELMVPRLE 187
Cdd:PRK06964 176 LPTILSRCRQFPMTVPAPEAAAAWLA 201
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
98-222 |
2.39e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 51.44 E-value: 2.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 98 IDIIRGpILSFASTRTIFKKGfKLVILDEADAMTQDAQNALRRVIEKfTENTRFCLICNYLSKIIPALQSRCTRFRFGPL 177
Cdd:PRK07399 106 LEQIRE-IKRFLSRPPLEAPR-KVVVIEDAETMNEAAANALLKTLEE-PGNGTLILIAPSPESLLPTIVSRCQIIPFYRL 182
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 332164786 178 TPELMVPRLEHVVEEEKVDISedgMKALVTLSSGDMRRAL---NILQS 222
Cdd:PRK07399 183 SDEQLEQVLKRLGDEEILNIN---FPELLALAQGSPGAAIaniEQLQS 227
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
27-72 |
2.69e-07 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 51.28 E-value: 2.69e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 332164786 27 RPQTLNDLISHQDILSTIQKFIN-----EDRLPHLLLYGPPGTGKTS--TILA 72
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFIEaakkrGEALDHVLLYGPPGLGKTTlaNIIA 72
|
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
177-240 |
3.00e-07 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 47.11 E-value: 3.00e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 332164786 177 LTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNIL-QSTNMAFGKVTEETVYTCTG 240
Cdd:cd18137 1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLdQAIAFGGGRVTLDDVREMLG 65
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
118-183 |
4.16e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 50.96 E-value: 4.16e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 332164786 118 GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMV 183
Cdd:PRK06090 108 GYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAM 173
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
56-172 |
9.93e-07 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 48.05 E-value: 9.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 56 LLLYGPPGTGKTSTILACAKQLykDKEFgsmvleLNASDDRGIDIIRGPilSFASTRTIF----KKGFKLVILDEADAM- 130
Cdd:cd19481 29 ILLYGPPGTGKTLLAKALAGEL--GLPL------IVVKLSSLLSKYVGE--SEKNLRKIFerarRLAPCILFIDEIDAIg 98
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 332164786 131 -----------TQDAQNALRRVIEKFTENTRFCLIC--NYLSKIIPALQsRCTRF 172
Cdd:cd19481 99 rkrdssgesgeLRRVLNQLLTELDGVNSRSKVLVIAatNRPDLLDPALL-RPGRF 152
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
52-79 |
1.11e-06 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 48.77 E-value: 1.11e-06
10 20
....*....|....*....|....*...
gi 332164786 52 RLPHLLLYGPPGTGKTSTILACAKQLYK 79
Cdd:cd18038 19 RPPPYIIFGPPGTGKTVTLVEAILQVLR 46
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
27-72 |
1.81e-06 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 47.11 E-value: 1.81e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 332164786 27 RPQTLNDLISHQDILSTIQKFIN-----EDRLPHLLLYGPPGTGKT--STILA 72
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFIEaakqrGEALDHVLLYGPPGLGKTtlANIIA 54
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
27-72 |
2.03e-06 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 48.92 E-value: 2.03e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 332164786 27 RPQTLNDLISHQDILSTIQKFIN-----EDRLPHLLLYGPPGTGKT--STILA 72
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIEaakkrGEALDHVLLYGPPGLGKTtlAHIIA 75
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
29-220 |
2.76e-06 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 48.45 E-value: 2.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 29 QTLNDLISHQDILSTIQKFI-----NEDRLPHLLLYGPPGTGKTS--TILACakqlykdkefgsmvlELNASddrgIDII 101
Cdd:TIGR00635 1 KLLAEFIGQEKVKEQLQLFIeaakmRQEALDHLLLYGPPGLGKTTlaHIIAN---------------EMGVN----LKIT 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 102 RGPIL----SFASTRTIFKKGFKLVIlDEADAMTQDAQNALRRVIEKFT----------------ENTRFCLI--CNYLS 159
Cdd:TIGR00635 62 SGPALekpgDLAAILTNLEEGDVLFI-DEIHRLSPAVEELLYPAMEDFRldivigkgpsarsvrlDLPPFTLVgaTTRAG 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 332164786 160 KIIPALQSrctrfRFGpltpelMVPRLEHVVEEE------------KVDISEDGMKALVTLSSGDMRRALNIL 220
Cdd:TIGR00635 141 MLTSPLRD-----RFG------IILRLEFYTVEElaeivsrsagllNVEIEPEAALEIARRSRGTPRIANRLL 202
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
31-217 |
4.79e-06 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 47.19 E-value: 4.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 31 LNDLISHQDILSTIQKFINE----DRL--------PHLLLYGPPGTGKTSTILACAKQLykdkefGSMVLELNASddrgi 98
Cdd:COG1223 1 LDDVVGQEEAKKKLKLIIKElrrrENLrkfglwppRKILFYGPPGTGKTMLAEALAGEL------KLPLLTVRLD----- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 99 diirGPILSF-----ASTRTIFK--KGFKLVI-LDEADAMTQD--AQNA---LRRVIEKF-----TENTRFCLIC--NYL 158
Cdd:COG1223 70 ----SLIGSYlgetaRNLRKLFDfaRRAPCVIfFDEFDAIAKDrgDQNDvgeVKRVVNALlqeldGLPSGSVVIAatNHP 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 332164786 159 SKIIPALQSRC-TRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM---KALVTLSSGDMRRAL 217
Cdd:COG1223 146 ELLDSALWRRFdEVIEFPLPDKEERKEILELNLKKFPLPFELDLKklaKKLEGLSGADIEKVL 208
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
38-220 |
5.76e-06 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 47.54 E-value: 5.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 38 QDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKD-KEFGSMV--LELNASDDR---GI------DIIRGPI 105
Cdd:COG1474 36 EELASALRPALRGERPSNVLIYGPTGTGKTAVAKYVLEELEEEaEERGVDVrvVYVNCRQAStryRVlsrileELGSGED 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 106 LSF--ASTRTIFKKGFK---------LVILDEADAMTQDAQN----ALRRVIEKFtENTRFCLIC-----NYLSKIIPAL 165
Cdd:COG1474 116 IPStgLSTDELFDRLYEalderdgvlVVVLDEIDYLVDDEGDdllyQLLRANEEL-EGARVGVIGisndlEFLENLDPRV 194
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 332164786 166 QSR--CTRFRFGPLT-PEL---MVPRLEH-----VVEEEKVD-ISedgmkALVTLSSGDMRRALNIL 220
Cdd:COG1474 195 KSSlgEEEIVFPPYDaDELrdiLEDRAELafydgVLSDEVIPlIA-----ALAAQEHGDARKAIDLL 256
|
|
| AAA_24 |
pfam13479 |
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins. |
56-151 |
6.06e-06 |
|
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
Pssm-ID: 433243 Cd Length: 199 Bit Score: 46.17 E-value: 6.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 56 LLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLElnasDDRGIDI-IRGPILSF----ASTRTIFKKGFKLVILDEADAM 130
Cdd:pfam13479 5 ILIYGPSGIGKTTFAKTLPKPLFLDTEKGSKALD----GDRFPDIvIRDSWQDFldaiDELTAAELADYKTIVIDTVDWL 80
|
90 100
....*....|....*....|.
gi 332164786 131 TQDAQNALRRVIEKFTENTRF 151
Cdd:pfam13479 81 ERLCLAYICKQNGKGSSIEDG 101
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
191-235 |
1.23e-05 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 42.84 E-value: 1.23e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 332164786 191 EEEKVDISEDGMKALVTLSSGDMRRALNIL----QSTNMAFGK--VTEETV 235
Cdd:pfam16193 1 GGLKIELDDEALEALAELADGDARRALNALelavLSTPPDDGGihITLEIL 51
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
167-235 |
1.27e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 46.78 E-value: 1.27e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 332164786 167 SRCTRFRFGPLTPELMVPRLEHVVEEEKVDiSEDgmKALVTLS---SGDMRRALNIL-QSTNMAFGKVTEETV 235
Cdd:PRK07994 168 SRCLQFHLKALDVEQIRQQLEHILQAEQIP-FEP--RALQLLAraaDGSMRDALSLTdQAIASGNGQVTTDDV 237
|
|
| PRK07993 |
PRK07993 |
DNA polymerase III subunit delta'; Validated |
118-222 |
1.38e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181190 [Multi-domain] Cd Length: 334 Bit Score: 46.21 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 118 GFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHvveeeKVDI 197
Cdd:PRK07993 108 GAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCRLHYLAPPPEQYALTWLSR-----EVTM 182
|
90 100
....*....|....*....|....*
gi 332164786 198 SEDGMKALVTLSSGDMRRALNILQS 222
Cdd:PRK07993 183 SQDALLAALRLSAGAPGAALALLQP 207
|
|
| PRK08699 |
PRK08699 |
DNA polymerase III subunit delta'; Validated |
51-172 |
2.26e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181538 [Multi-domain] Cd Length: 325 Bit Score: 45.63 E-value: 2.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 51 DRLPH-LLLYGPPGTGKTSTILACAKQLYKDKE---------------FGS-------MVLELNASDDRG-------IDI 100
Cdd:PRK08699 18 ERRPNaWLFAGKKGIGKTAFARFAAQALLCETPapghkpcgecmschlFGQgshpdfyEITPLSDEPENGrkllqikIDA 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 332164786 101 IRgPILSFASTrTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRF 172
Cdd:PRK08699 98 VR-EIIDNVYL-TSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKM 167
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
177-221 |
1.36e-04 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 39.92 E-value: 1.36e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 332164786 177 LTPELMVPRLEHVVEEE------KVDISEDGMKALVTLSSGDMRRALNILQ 221
Cdd:cd18139 1 LSEEDLEKLLKRALEDKerggdrKVTIDDEALELLAEAADGDARSALNLLE 51
|
|
| RecA-like_BCS1 |
cd19510 |
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ... |
40-77 |
3.56e-04 |
|
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410918 [Multi-domain] Cd Length: 153 Bit Score: 40.41 E-value: 3.56e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 332164786 40 ILSTIQKFIN-----EDRLPH----LLLYGPPGTGKTSTILACAKQL 77
Cdd:cd19510 1 IIDDLKDFIKnedwyNDRGIPyrrgYLLYGPPGTGKSSFIAALAGEL 47
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
57-235 |
4.80e-04 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 41.09 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 57 LLYGPPGTGKTSTILACAKQ-----------LYKDKEF-GSMVLELNASDDRG--IDIIRGPILSFASTRTifkkgfkLV 122
Cdd:COG2842 54 VVYGESGVGKTTAAREYANRnpnviyvtaspSWTSKELlEELAEELGIPAPPGtiADLRDRILERLAGTGR-------LL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 123 ILDEADAMTQDAQNALRRVIEKftENTRFCLICN--YLSKI--IPALQSRCT-RFRFGPLTPE---LMVPRLEHVVEEEK 194
Cdd:COG2842 127 IIDEADHLKPKALEELRDIHDE--TGVGVVLIGMerLPAKLkrYEQLYSRIGfWVEFKPLSLEdvrALAEAWGELTDPDL 204
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 332164786 195 VdisedgmKALVTLSSGDMRRALNIL-----QSTNMAFGKVTEETV 235
Cdd:COG2842 205 L-------ELLHRITRGNLRRLDRTLrlaarAAKRNGLTKITLDHV 243
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
55-221 |
7.62e-04 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 41.37 E-value: 7.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 55 HLLLYGPPGTGKTSTILACAKQLYkdkefgsmvlelnasddrGIDIIRGPIL---------------SFASTRTIFKKGF 119
Cdd:TIGR03922 314 HMLFAGPPGTGKTTIARVVAKIYC------------------GLGVLRKPLVrevsradligqyigeSEAKTNEIIDSAL 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 120 KLVI-LDEADAMTQ-----------DAQNALRRVIEkfTENTRFCLICNYLSKII-------PALQSRCTR-FRFGPLTP 179
Cdd:TIGR03922 376 GGVLfLDEAYTLVEtgygqkdpfglEAIDTLLARME--NDRDRLVVIGAGYRKDLdkflevnEGLRSRFTRvIEFPSYSP 453
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 332164786 180 ELMVpRLEHVVEEEKVDISEDG-----MKALVTLS-------SGDMRRALNILQ 221
Cdd:TIGR03922 454 DELV-EIARRMATERDSVLDDAaadalLEAATTLAqdttpdaNGDLRRGLDIAG 506
|
|
| RecA-like_NSF-SEC18_r1-like |
cd19504 |
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ... |
56-130 |
1.03e-03 |
|
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410912 [Multi-domain] Cd Length: 177 Bit Score: 39.40 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 56 LLLYGPPGTGKTstilACAKQLykdkefGSMvleLNASDDRgidIIRGP-IL------SFASTRTIFK------------ 116
Cdd:cd19504 38 ILLYGPPGTGKT----LMARQI------GKM---LNAREPK---IVNGPeILnkyvgeSEANIRKLFAdaeeeqrrlgan 101
|
90
....*....|....
gi 332164786 117 KGFKLVILDEADAM 130
Cdd:cd19504 102 SGLHIIIFDEIDAI 115
|
|
| PRK10787 |
PRK10787 |
DNA-binding ATP-dependent protease La; Provisional |
20-199 |
2.68e-03 |
|
DNA-binding ATP-dependent protease La; Provisional
Pssm-ID: 182730 [Multi-domain] Cd Length: 784 Bit Score: 39.54 E-value: 2.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 20 LPWVEkyRPQTLNDLISHQDILST-----------------IQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLykdke 82
Cdd:PRK10787 301 VPWNA--RSKVKKDLRQAQEILDTdhyglervkdrileylaVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKAT----- 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 83 fGSMVLELNASDDRGIDIIRGPILSFAST------RTIFKKGFK--LVILDEADAMTQDAQ----NALRRVIEKfTENTR 150
Cdd:PRK10787 374 -GRKYVRMALGGVRDEAEIRGHRRTYIGSmpgkliQKMAKVGVKnpLFLLDEIDKMSSDMRgdpaSALLEVLDP-EQNVA 451
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 332164786 151 F---CLICNY-LSKIIPALQSRCTRFRfGPLTPELMVPRLEHVVEEEKVDISE 199
Cdd:PRK10787 452 FsdhYLEVDYdLSDVMFVATSNSMNIP-APLLDRMEVIRLSGYTEDEKLNIAK 503
|
|
| AAA_11 |
pfam13086 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
44-79 |
2.92e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Pssm-ID: 404072 [Multi-domain] Cd Length: 248 Bit Score: 38.86 E-value: 2.92e-03
10 20 30
....*....|....*....|....*....|....*.
gi 332164786 44 IQKFINEDRLphLLLYGPPGTGKTSTILACAKQLYK 79
Cdd:pfam13086 6 IRSALSSSHF--TLIQGPPGTGKTTTIVELIRQLLS 39
|
|
| PRK06871 |
PRK06871 |
DNA polymerase III subunit delta'; Validated |
95-169 |
3.32e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180738 [Multi-domain] Cd Length: 325 Bit Score: 38.95 E-value: 3.32e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 332164786 95 DRGIDIIR---GPILSFAStrtifKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRC 169
Cdd:PRK06871 86 DIGVDQVReinEKVSQHAQ-----QGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRC 158
|
|
| PRK07132 |
PRK07132 |
DNA polymerase III subunit delta'; Validated |
120-174 |
3.67e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180855 [Multi-domain] Cd Length: 299 Bit Score: 38.55 E-value: 3.67e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 332164786 120 KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRF 174
Cdd:PRK07132 92 KILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNV 146
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
56-131 |
3.68e-03 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 37.66 E-value: 3.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 56 LLLYGPPGTGKTSTILACAKQLykdkefGSMVLELNasddrGIDIIRG-PILSFASTRTIFKKGFK----LVILDEADAM 130
Cdd:cd19503 37 VLLHGPPGTGKTLLARAVANEA------GANFLSIS-----GPSIVSKyLGESEKNLREIFEEARShapsIIFIDEIDAL 105
|
.
gi 332164786 131 T 131
Cdd:cd19503 106 A 106
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
48-81 |
4.38e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 37.48 E-value: 4.38e-03
10 20 30
....*....|....*....|....*....|....
gi 332164786 48 INEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK 81
Cdd:pfam13191 19 VRSGRPPSVLLTGEAGTGKTTLLRELLRALERDG 52
|
|
| RecA-like_Pch2-like |
cd19508 |
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as ... |
34-92 |
4.48e-03 |
|
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as Thyroid hormone receptor interactor 13 (TRIP13) and 16E1BP) is a key regulator of specific chromosomal events, like the control of G2/prophase processes such as DNA break formation and recombination, checkpoint signaling, and chromosome synapsis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion
Pssm-ID: 410916 [Multi-domain] Cd Length: 199 Bit Score: 37.81 E-value: 4.48e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 332164786 34 LISHQDILSTIqkfINEDRLphLLLYGPPGTGKTSTILACAKQL---YKDKEFGSMVLELNA 92
Cdd:cd19508 38 LFSDKNVNTNL---ITWNRL--VLLHGPPGTGKTSLCKALAQKLsirLSSRYRYGQLIEINS 94
|
|
| PRK06581 |
PRK06581 |
DNA polymerase III subunit delta'; Validated |
93-169 |
5.14e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 235833 [Multi-domain] Cd Length: 263 Bit Score: 37.90 E-value: 5.14e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 332164786 93 SDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRC 169
Cdd:PRK06581 64 SNAKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRC 140
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
9-77 |
5.57e-03 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 38.06 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 9 QEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTI-QKFINEDRLPHL------------LLYGPPGTGKTSTILACAK 75
Cdd:COG1222 55 LTQKRLGTPRGTAVPAESPDVTFDDIGGLDEQIEEIrEAVELPLKNPELfrkygieppkgvLLYGPPGTGKTLLAKAVAG 134
|
..
gi 332164786 76 QL 77
Cdd:COG1222 135 EL 136
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
55-143 |
5.90e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 36.50 E-value: 5.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 55 HLLLYGPPGTGKTSTILACAKQLYKDKEFgsMVL---ELNASDDRGIDIIRGPILSF--ASTRTIFKKGfKLVILDEADA 129
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVF--YVQltrDTTEEDLFGRRNIDPGGASWvdGPLVRAAREG-EIAVLDEINR 77
|
90
....*....|....
gi 332164786 130 MTQDAQNALRRVIE 143
Cdd:pfam07728 78 ANPDVLNSLLSLLD 91
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
56-77 |
6.29e-03 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 36.06 E-value: 6.29e-03
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
24-180 |
6.75e-03 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 38.25 E-value: 6.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 24 EKYRPQTLNDLISHQDILSTIqkfinEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGS----MVLELN--ASDDRG 97
Cdd:COG5635 156 DLYVPLNLLERIESLKRLELL-----EAKKKRLLILGEPGSGKTTLLRYLALELAERYLDAEdpipILIELRdlAEEASL 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 98 IDIIRGPILSFAST-----RTIFKKGFKLVILD-----EADAMTQDAQNALRRVIEKFtENTRFCLICNYLSKIIPALQs 167
Cdd:COG5635 231 EDLLAEALEKRGGEpedalERLLRNGRLLLLLDgldevPDEADRDEVLNQLRRFLERY-PKARVIITSRPEGYDSSELE- 308
|
170
....*....|...
gi 332164786 168 RCTRFRFGPLTPE 180
Cdd:COG5635 309 GFEVLELAPLSDE 321
|
|
| DEXXQc_SETX |
cd18042 |
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in ... |
57-72 |
7.03e-03 |
|
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in transcription, neurogenesis, and antiviral response. SEXT is an R-loop-associated protein that is thought to function as an RNA/DNA helicase. R-loops consist of RNA/DNA hybrids, formed during transcription when nascent RNA hybridizes to the DNA template strand, displacing the non-template DNA strand. Mutations in SETX are linked to two neurodegenerative disorders: ataxia with oculomotor apraxia type 2 (AOA2) and amyotrophic lateral sclerosis type 4 (ALS4). S. cerevisiae homolog splicing endonuclease 1 (Sen1) is an exclusively nuclear protein, important for nucleolar organization. S. cerevisiae Sen1 and its ortholog, the Schizosaccharomyces pombe Sen1, share conserved domains and belong to the family I class of helicases. Both proteins translocate 5' to 3' and unwind both DNA and RNA duplexes and also RNA/DNA hybrids in vitro. SETX is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438712 [Multi-domain] Cd Length: 218 Bit Score: 37.19 E-value: 7.03e-03
|
| AAA_14 |
pfam13173 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
56-153 |
8.15e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 463799 [Multi-domain] Cd Length: 128 Bit Score: 36.03 E-value: 8.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 332164786 56 LLLYGPPGTGKTSTILACAKQLYKDKEFgsmvLELNASDDRGIDIIRGPILSFAstRTIFKKGFKLVILDEAdAMTQDAQ 135
Cdd:pfam13173 5 LVITGPRQVGKTTLLLQLIKELLPPENI----LYINLDDPRLLKLADFELLELF--LELLYPGKTYLFLDEI-QRVPDWE 77
|
90
....*....|....*...
gi 332164786 136 NALRRVIEKFtENTRFCL 153
Cdd:pfam13173 78 LALKRLYDDG-PNGRVIL 94
|
|
| AAA_7 |
pfam12775 |
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 ... |
55-92 |
9.90e-03 |
|
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 proteins. Cytoplasmic dynein-2 (dynein-2) performs intraflagellar transport and is associated with human skeletal ciliopathies. Dyneins share a conserved motor domain that couples cycles of ATP hydrolysis with conformational changes to produce movement. Structural analysis reveal that the motor's ring consists of six AAA+ domains (ATPases associated with various cellular activities (AAA1-AAA6). This is the third nucleotide binding sites in the dynein motor. However, AAA3 has lost the catalytic residues necessary for ATP hydrolysis (the Walker B glutamate, the arginine finger, sensor-I and sensor-II motifs).
Pssm-ID: 463698 [Multi-domain] Cd Length: 179 Bit Score: 36.60 E-value: 9.90e-03
10 20 30
....*....|....*....|....*....|....*...
gi 332164786 55 HLLLYGPPGTGKTSTILACAKQLYKDKeFGSMVLELNA 92
Cdd:pfam12775 33 PVLLVGPTGTGKTVIIQNLLRKLDKEK-YLPLFINFSA 69
|
|
| |
