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Conserved domains on  [gi|386768294|ref|NP_001246421|]
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hu li tai shao, isoform Q [Drosophila melanogaster]

Protein Classification

class II aldolase/adducin head domain-containing protein; L-fuculose-phosphate aldolase( domain architecture ID 10087020)

class II aldolase/adducin head domain-containing protein involved in catalyzing central steps of carbohydrate metabolism; it promotes carbon-carbon bond cleavage and stabilizes enolate intermediates using divalent cations| L-fuculose-phosphate aldolase catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde; Also able to catalyze the reversible cleavage of D-ribulose 1-phosphate, but FucA has a higher affinity for L-fuculose 1-phosphate and L-lactaldehyde than for D-ribulose 1-phosphate and glycolaldehyde, respectively

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 116-323 1.15e-71

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


:

Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 232.26  E-value: 1.15e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 116 EKILRcKLAATFRLLDLYGWTQGLGAQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVE--QGTTNFGgnks 193
Cdd:cd00398    1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSARDR-DRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEgkKPSSETP---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 194 hfvLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL---GEITTHAYTGLFDEEERNRLVRSLG-PNSKV 269
Cdd:cd00398   75 ---LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPETGEDEIGTQRALGfPNSKA 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 386768294 270 ILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVGL----DNLVLIPEESRKAI 323
Cdd:cd00398  152 VLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGqlppISLELLNKEYLRKH 209
 
Name Accession Description Interval E-value
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 116-323 1.15e-71

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 232.26  E-value: 1.15e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 116 EKILRcKLAATFRLLDLYGWTQGLGAQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVE--QGTTNFGgnks 193
Cdd:cd00398    1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSARDR-DRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEgkKPSSETP---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 194 hfvLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL---GEITTHAYTGLFDEEERNRLVRSLG-PNSKV 269
Cdd:cd00398   75 ---LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPETGEDEIGTQRALGfPNSKA 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 386768294 270 ILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVGL----DNLVLIPEESRKAI 323
Cdd:cd00398  152 VLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGqlppISLELLNKEYLRKH 209
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 119-389 3.59e-57

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 195.07  E-value: 3.59e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQgtTNFGGNKSHFVLH 198
Cdd:PRK07044  17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDD--SPYPVNPAGFTIH 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 199 SVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDAC-VLGEITTHAYTGL-FDEEERNRLVRSLGPNsKVILLTNHG 276
Cdd:PRK07044  95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALqFYGRLAYHDYEGIaLDLDEGERLVADLGDK-PAMLLRNHG 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 277 ALCCGETIEEAFFAACHIVQACETQLKLLPVGLDnLVLIPEESRKAIYEQSRRPPEDLEkkfaavaaaedgaataekdaa 356
Cdd:PRK07044 174 LLTVGRTVAEAFLLMYTLERACEIQVAAQAGGGE-LVLPPPEVAERTARQSLFDPGAGA--------------------- 231

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 386768294 357 eavpkvgsppkwrvGGAEFEALMRMLD--NAGYRT 389
Cdd:PRK07044 232 --------------GELAWPALLRKLDriDPGYRD 252
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 121-302 2.17e-46

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 163.10  E-value: 2.17e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294  121 CKLAATFRLLDLYGWTQGLGAQITARlkVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGttnfGGNKSHFVLHSV 200
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVR--LPGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG----LKPSSETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294  201 VHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL--GEITTHAYTGLFDEEERNRLVRSLGPNSKVILLTNHGAL 278
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYTPGTEELGERIAEALGGDRKAVLLRNHGLL 154

                         170       180
                  ....*....|....*....|....
gi 386768294  279 CCGETIEEAFFAACHIVQACETQL 302
Cdd:pfam00596 155 VWGKTLEEAFYLAEELERAAEIQL 178
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 119-328 4.88e-43

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 154.60  E-value: 4.88e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYGWTQGLGAQITARlkVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGttnfGGNKSHFVLH 198
Cdd:COG0235    6 LREELAAAGRRLARRGLVDGTAGNISVR--LDDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGD----LKPSSETPLH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 199 SVVHAARPDIRCAI-----YIgcspvVAISSLKTGLLPL--TKDACVLGEITTHAYTGLFDEEERNRLVRSLGpNSKVIL 271
Cdd:COG0235   80 LAIYRARPDVGAVVhthspYA-----TALSALGEPLPPLeqTEAAAFLGDVPVVPYAGPGTEELAEAIAEALG-DRPAVL 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 386768294 272 LTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVGldNLVLIPEESRKAIYEQSR 328
Cdd:COG0235  154 LRNHGVVVWGKDLAEAFDRAEVLEEAARIQLLALALG--GPLVLSDEEIDKLARKFG 208
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 123-302 1.57e-40

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 147.01  E-value: 1.57e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294   123 LAATFRLLDLYGWTQGLGAQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTnfGGNKSHFVLHSVVH 202
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVG-EEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGG--PKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294   203 AARPDIRCAIYIGCSPVVAISSLKTGLLPLTKD---ACVLGEITTHAYT--GLFDEEERNRLVRSLGP---NSKVILLTN 274
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALGKPLPLLPTEqaaAFLGGEIPYAPYAgpGTELAEEGAELAEALAEalpDRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 386768294   275 HGALCCGETIEEAFFAACHIVQACETQL 302
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
 
Name Accession Description Interval E-value
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 116-323 1.15e-71

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 232.26  E-value: 1.15e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 116 EKILRcKLAATFRLLDLYGWTQGLGAQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVE--QGTTNFGgnks 193
Cdd:cd00398    1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSARDR-DRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEgkKPSSETP---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 194 hfvLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL---GEITTHAYTGLFDEEERNRLVRSLG-PNSKV 269
Cdd:cd00398   75 ---LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPETGEDEIGTQRALGfPNSKA 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 386768294 270 ILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVGL----DNLVLIPEESRKAI 323
Cdd:cd00398  152 VLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGqlppISLELLNKEYLRKH 209
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 119-389 3.59e-57

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 195.07  E-value: 3.59e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQgtTNFGGNKSHFVLH 198
Cdd:PRK07044  17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDD--SPYPVNPAGFTIH 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 199 SVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDAC-VLGEITTHAYTGL-FDEEERNRLVRSLGPNsKVILLTNHG 276
Cdd:PRK07044  95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALqFYGRLAYHDYEGIaLDLDEGERLVADLGDK-PAMLLRNHG 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 277 ALCCGETIEEAFFAACHIVQACETQLKLLPVGLDnLVLIPEESRKAIYEQSRRPPEDLEkkfaavaaaedgaataekdaa 356
Cdd:PRK07044 174 LLTVGRTVAEAFLLMYTLERACEIQVAAQAGGGE-LVLPPPEVAERTARQSLFDPGAGA--------------------- 231

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 386768294 357 eavpkvgsppkwrvGGAEFEALMRMLD--NAGYRT 389
Cdd:PRK07044 232 --------------GELAWPALLRKLDriDPGYRD 252
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 121-302 2.17e-46

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 163.10  E-value: 2.17e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294  121 CKLAATFRLLDLYGWTQGLGAQITARlkVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGttnfGGNKSHFVLHSV 200
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVR--LPGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG----LKPSSETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294  201 VHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL--GEITTHAYTGLFDEEERNRLVRSLGPNSKVILLTNHGAL 278
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYTPGTEELGERIAEALGGDRKAVLLRNHGLL 154

                         170       180
                  ....*....|....*....|....
gi 386768294  279 CCGETIEEAFFAACHIVQACETQL 302
Cdd:pfam00596 155 VWGKTLEEAFYLAEELERAAEIQL 178
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 119-328 4.88e-43

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 154.60  E-value: 4.88e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYGWTQGLGAQITARlkVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGttnfGGNKSHFVLH 198
Cdd:COG0235    6 LREELAAAGRRLARRGLVDGTAGNISVR--LDDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGD----LKPSSETPLH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 199 SVVHAARPDIRCAI-----YIgcspvVAISSLKTGLLPL--TKDACVLGEITTHAYTGLFDEEERNRLVRSLGpNSKVIL 271
Cdd:COG0235   80 LAIYRARPDVGAVVhthspYA-----TALSALGEPLPPLeqTEAAAFLGDVPVVPYAGPGTEELAEAIAEALG-DRPAVL 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 386768294 272 LTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVGldNLVLIPEESRKAIYEQSR 328
Cdd:COG0235  154 LRNHGVVVWGKDLAEAFDRAEVLEEAARIQLLALALG--GPLVLSDEEIDKLARKFG 208
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 123-302 1.57e-40

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 147.01  E-value: 1.57e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294   123 LAATFRLLDLYGWTQGLGAQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTnfGGNKSHFVLHSVVH 202
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVG-EEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGG--PKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294   203 AARPDIRCAIYIGCSPVVAISSLKTGLLPLTKD---ACVLGEITTHAYT--GLFDEEERNRLVRSLGP---NSKVILLTN 274
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALGKPLPLLPTEqaaAFLGGEIPYAPYAgpGTELAEEGAELAEALAEalpDRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 386768294   275 HGALCCGETIEEAFFAACHIVQACETQL 302
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
PRK06208 PRK06208
class II aldolase/adducin family protein;
122-330 2.55e-34

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 132.42  E-value: 2.55e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 122 KLAATFRLLDLYGWTQGLGAQITARlkvDQEY---FLVNPYGLLYHEITASALNKVDMQGQIVEqgtTNFGGNKSHFVLH 198
Cdd:PRK06208  46 RLAAAFRLFARFGFDEGLAGHITAR---DPELpdhFWVNPLGVHFSQIKVSDLLLVDHDGEVVE---GDRPLNRAAFAIH 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 199 SVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLGEitTHA----YTGL-FDEEERNRLVRSLGPNSKVIlLT 273
Cdd:PRK06208 120 SAIHEARPDVVAAAHTHSTYGKAWSTLGRPLDPITQDACAFYE--DHAlfddFTGVvVDTSEGRRIAAALGTHKAVI-LQ 196

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 386768294 274 NHGALCCGETIEEAFFAACHIVQACETQLKLLPVGldNLVLIPEESRKAIYEQSRRP 330
Cdd:PRK06208 197 NHGLLTVGPSVDAAAWWFIALERACQTQLLAEAAG--PPQPIDHETARHTRSQVGSE 251
PRK06661 PRK06661
hypothetical protein; Provisional
 123-323 4.53e-32

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 124.56  E-value: 4.53e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 123 LAATFRLLDLYGWTQGLGAQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFggNKSHFVLHSVVH 202
Cdd:PRK06661   7 LAAAYRIMAYLSLDDHTYTHLSARPK-NADFYYIYPFGLRFEEVTTENLLKVSLDGQILEGEEYQY--NKTGYFIHGSIY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 203 AARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLGE-ITTHAYTGLF--DEEERNRLVRSLGPNsKVILLTNHGALC 279
Cdd:PRK06661  84 KTRPDISAIFHYHTPASIAVSALKCGLLPISQWALHFYDrISYHNYNSLAldADKQSSRLVNDLKQN-YVMLLRNHGAIT 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 386768294 280 CGETIEEAFFAACHIVQACETQLKLLPVGLDNLVLIPEE-SRKAI 323
Cdd:PRK06661 163 CGKTIHEAMFYTYHLEQACKTQCLLNSTKKQELIIPSVEiCKKTV 207
PRK06486 PRK06486
aldolase;
119-328 5.70e-22

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 96.32  E-value: 5.70e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEqgttnfGGNK---SHF 195
Cdd:PRK06486  27 ARVDLAACFRAAARHGLEEGICNHFSAVLPGHDDLFLVNPYGYAFSEITASDLLICDFDGNVLA------GRGEpeaTAF 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 196 VLHSVVHAARPDIRCAIYIGCSPVVAISSLK-TGLLPLTKDAC-VLGEITTHA-YTGL-FDEEERNRLVRSLGpNSKVIL 271
Cdd:PRK06486 101 FIHARIHRAIPRAKAAFHTHMPYATALSLTEgRPLTTLGQTALkFYGRTAVDEdYNGLaLDAAEGDRIARAMG-DADIVF 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 386768294 272 LTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVGLDnLVLIPEESRKAIYEQSR 328
Cdd:PRK06486 180 LKNHGVMVCGPRIAEAWDDLYYLERACEVQVLAMSTGRP-LVPVDPAIAAAVARQMR 235
PRK07490 PRK07490
hypothetical protein; Provisional
 119-321 5.10e-17

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 81.30  E-value: 5.10e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVD------MQGQIVEQGTTnfggnk 192
Cdd:PRK07490  11 IRVDLAAAFRWIARLGMHEAVANHFSAAVSADGKQFLLNPKWKHFSRIRASDLLLLDaddpstAERPDVPDATA------ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 193 shFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTG-LLPLTKDACVLGE---ITTHaYTGLFDEEERNRLVRSLGpNSK 268
Cdd:PRK07490  85 --WAIHGQIHRRLPHARCVMHVHSVYATALACLADPtLPPIDQNTARFFNrvaVDTL-YGGMALEEEGERLAGLLG-DKR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 386768294 269 VILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVGLDNLVLIPEESRK 321
Cdd:PRK07490 161 RLLMGNHGVLVTGDTVAEAFDDLYYFERACQTYITALSTGQPLRVLSDAVAEK 213
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 119-308 1.06e-16

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 80.45  E-value: 1.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFlVNPYGLLYHEITASALNKVDMQGQIVE-QGTTNfGGNKshfvL 197
Cdd:PRK07090  31 LRQKLALTCRILFDAGHDSGLAGQITARAEAPGTYY-TQRLGLGFDEITASNLLLVDEDLNVLDgEGMPN-PANR----F 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 198 HSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL-------------------GEITTHAytglfdeeernr 258
Cdd:PRK07090 105 HSWIYRARPDVNCIIHTHPPHVAALSMLEVPLVVSHMDTCPLyddcaflkdwpgvpvgneeGEIISAA------------ 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 386768294 259 lvrsLGpNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLPVG 308
Cdd:PRK07090 173 ----LG-DKRAILLSHHGQLVAGKSIEEACVLALLIERAARLQLLAMAAG 217
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
134-318 4.85e-07

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 51.28  E-value: 4.85e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 134 GWTQGLGAQITARLkvdQEYFLVNPYGLLYHEITASALNKVDMQGQiVEQGTTNfggnKSHFVLHSVVHAARPDIRCAIY 213
Cdd:PRK08087  21 GLNQGTAGNVSVRY---QDGMLITPTGIPYEKLTESHIVFVDGNGK-HEEGKLP----SSEWRFHMAAYQTRPDANAVVH 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 214 ---IGCspvVAISSLKTGLLPLTKDACVLG--EITTHAYtGLFDEEERNRLVRSLGPNSKVILLTNHGALCCGETIEEAF 288
Cdd:PRK08087  93 nhaVHC---TAVSILNRPIPAIHYMIAAAGgnSIPCAPY-ATFGTRELSEHVALALKNRKATLLQHHGLIACEVNLEKAL 168

                        170       180       190
                 ....*....|....*....|....*....|
gi 386768294 289 FAACHIVQACETQLKLLPVGLDNLVLIPEE 318
Cdd:PRK08087 169 WLAHEVEVLAQLYLKTLAITDPVPVLSDEE 198
PRK08130 PRK08130
putative aldolase; Validated
 116-291 7.38e-06

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 47.56  E-value: 7.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 116 EKILR---CKLAATF--RlldlyGWTQGLGAQITARLkvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEqgttnfgG 190
Cdd:PRK08130   3 EQALReeiVRLGRSLfqR-----GYTVGSAGNISARL--DDGGWLVTPTGSCLGRLDPARLSKVDADGNWLS-------G 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 191 NK--SHFVLHSVVHAARPDIRCAIYIGCSPVVAISSL-----KTGLLPLTKDACV-LGEITTHAY--TGLFDEEERnrlV 260
Cdd:PRK08130  69 DKpsKEVPLHRAIYRNNPECGAVVHLHSTHLTALSCLggldpTNVLPPFTPYYVMrVGHVPLIPYyrPGDPAIAEA---L 145

                        170       180       190
                 ....*....|....*....|....*....|.
gi 386768294 261 RSLGPNSKVILLTNHGALCCGETIEEAFFAA 291
Cdd:PRK08130 146 AGLAARYRAVLLANHGPVVWGSSLEAAVNAT 176
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 119-291 5.22e-05

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 45.00  E-value: 5.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 119 LRCKLAATFRLLDLYG---WTQGlgaQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEqgttnfgGNKSHF 195
Cdd:PRK06557  11 LREEVCKLHLELPKYGlvvWTSG---NVSARDP-GTDLVVIKPSGVSYDDLTPEDMVVVDLDGNVVE-------GDLKPS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 196 V---LHSVVHAARPDIRcaiyigcSPVVAISSLKTGLLPLTKD-ACVL--------GEITTHAYTGLFDEEERNRLVRSL 263
Cdd:PRK06557  80 SdtaSHLYVYRHMPDVG-------GVVHTHSTYATAWAARGEPiPCVLtamadefgGPIPVGPFALIGDEAIGKGIVETL 152

                        170       180
                 ....*....|....*....|....*....
gi 386768294 264 -GPNSKVILLTNHGALCCGETIEEAFFAA 291
Cdd:PRK06557 153 kGGRSPAVLMQNHGVFTIGKDAEDAVKAA 181
PRK08333 PRK08333
aldolase;
117-291 6.10e-04

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 41.35  E-value: 6.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 117 KILRCKLAATFRLLDLYGWTQGLGAQITARLKvdqEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNfggnkSHFV 196
Cdd:PRK08333   2 RNVKAQLVKYSKLAHERGLTAAFGGNLSIRVG---NLVFIKATGSVMDELTREQVAVIDLNGNQLSSVRPS-----SEYR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 197 LHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLP-LTKDACV-LGEITTHAYTGLfDEEERNRLVRSLGPNSKVILLTN 274
Cdd:PRK08333  74 LHLAVYRNRPDVRAIAHLHPPYSIVASTLLEEELPiITPEAELyLKKIPILPFRPA-GSVELAEQVAEAMKEYDAVIMER 152

                        170
                 ....*....|....*..
gi 386768294 275 HGALCCGETIEEAFFAA 291
Cdd:PRK08333 153 HGIVTVGRSLREAFYKA 169
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
134-288 1.67e-03

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 40.50  E-value: 1.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768294 134 GWTQGLGAQITARLKvDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEqgttnfgGNK---SHFVLHSVVHAARPDIRC 210
Cdd:PRK06833  21 GLTKGTGGNISIFNR-EQGLMAITPSGIDYFEIKPEDIVIMDLDGKVVE-------GERkpsSELDMHLIFYRNREDINA 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386768294 211 AIYIGCSPVVAISSLKTGLLPLTKDACVLGEITTHAYTGLFDEEERNRLVRSLGPNSKVILLTNHGALCCGETIEEAF 288
Cdd:PRK06833  93 IVHTHSPYATTLACLGWELPAVHYLIAVAGPNVRCAEYATFGTKELAENAFEAMEDRRAVLLANHGLLAGANNLKNAF 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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