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Conserved domains on  [gi|392922690|ref|NP_001256787|]
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F-box domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_48 pfam17906
HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase ...
 24-73 7.30e-19

HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase comprises two HTH domains. This HTH domain binds in the DNA major groove to the transposons inverted repeats.


:

Pssm-ID: 465558 [Multi-domain]  Cd Length: 50  Bit Score: 76.79  E-value: 7.30e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 392922690   24 KNALRACILYEFLQKKPVFEAYKNFCKTIGDDLMEYREFDFWFYKIGKEN 73
Cdd:pfam17906   1 KIHLRHCILYEFLQGKSAAEAYRNICEVYGEDAVSERTFQRWFARFRSGD 50
F-box_CeFBXA-like cd22150
F-box domain found in Caenorhabditis elegans F-box domain-containing proteins (CeFBXA) and ...
 89-133 9.04e-10

F-box domain found in Caenorhabditis elegans F-box domain-containing proteins (CeFBXA) and similar proteins; The family includes a group of uncharacterized Caenorhabditis elegans F-box domain-containing proteins. They may be components of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


:

Pssm-ID: 438921  Cd Length: 46  Bit Score: 52.49  E-value: 9.04e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 392922690  89 LSNMPLKVVDTILENVEPIDRLPLGKVSQSLRSLTKAIGHGFKKV 133
Cdd:cd22150    1 LSDLPIEILNKILDKLDPIDRLVLRKVSRNLRDIVDNQDPGFKKI 45
 
Name Accession Description Interval E-value
HTH_48 pfam17906
HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase ...
 24-73 7.30e-19

HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase comprises two HTH domains. This HTH domain binds in the DNA major groove to the transposons inverted repeats.


Pssm-ID: 465558 [Multi-domain]  Cd Length: 50  Bit Score: 76.79  E-value: 7.30e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 392922690   24 KNALRACILYEFLQKKPVFEAYKNFCKTIGDDLMEYREFDFWFYKIGKEN 73
Cdd:pfam17906   1 KIHLRHCILYEFLQGKSAAEAYRNICEVYGEDAVSERTFQRWFARFRSGD 50
F-box_CeFBXA-like cd22150
F-box domain found in Caenorhabditis elegans F-box domain-containing proteins (CeFBXA) and ...
 89-133 9.04e-10

F-box domain found in Caenorhabditis elegans F-box domain-containing proteins (CeFBXA) and similar proteins; The family includes a group of uncharacterized Caenorhabditis elegans F-box domain-containing proteins. They may be components of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438921  Cd Length: 46  Bit Score: 52.49  E-value: 9.04e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 392922690  89 LSNMPLKVVDTILENVEPIDRLPLGKVSQSLRSLTKAIGHGFKKV 133
Cdd:cd22150    1 LSDLPIEILNKILDKLDPIDRLVLRKVSRNLRDIVDNQDPGFKKI 45
FBOX smart00256
A Receptor for Ubiquitination Targets;
92-132 3.29e-06

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 42.81  E-value: 3.29e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 392922690    92 MPLKVVDTILENVEPIDRLPLGKVSQSLRSLTKAIGHGFKK 132
Cdd:smart00256   1 LPDEILEEILSKLDPKDLLRLRKVSRKWRSLIDSHDFWFKL 41
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 89-124 8.31e-04

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 35.98  E-value: 8.31e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 392922690   89 LSNMPLKVVDTILENVEPIDRLPLGKVSQSLRSLTK 124
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVD 36
 
Name Accession Description Interval E-value
HTH_48 pfam17906
HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase ...
 24-73 7.30e-19

HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase comprises two HTH domains. This HTH domain binds in the DNA major groove to the transposons inverted repeats.


Pssm-ID: 465558 [Multi-domain]  Cd Length: 50  Bit Score: 76.79  E-value: 7.30e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 392922690   24 KNALRACILYEFLQKKPVFEAYKNFCKTIGDDLMEYREFDFWFYKIGKEN 73
Cdd:pfam17906   1 KIHLRHCILYEFLQGKSAAEAYRNICEVYGEDAVSERTFQRWFARFRSGD 50
F-box_CeFBXA-like cd22150
F-box domain found in Caenorhabditis elegans F-box domain-containing proteins (CeFBXA) and ...
 89-133 9.04e-10

F-box domain found in Caenorhabditis elegans F-box domain-containing proteins (CeFBXA) and similar proteins; The family includes a group of uncharacterized Caenorhabditis elegans F-box domain-containing proteins. They may be components of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438921  Cd Length: 46  Bit Score: 52.49  E-value: 9.04e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 392922690  89 LSNMPLKVVDTILENVEPIDRLPLGKVSQSLRSLTKAIGHGFKKV 133
Cdd:cd22150    1 LSDLPIEILNKILDKLDPIDRLVLRKVSRNLRDIVDNQDPGFKKI 45
FBOX smart00256
A Receptor for Ubiquitination Targets;
92-132 3.29e-06

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 42.81  E-value: 3.29e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 392922690    92 MPLKVVDTILENVEPIDRLPLGKVSQSLRSLTKAIGHGFKK 132
Cdd:smart00256   1 LPDEILEEILSKLDPKDLLRLRKVSRKWRSLIDSHDFWFKL 41
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 89-124 8.31e-04

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 35.98  E-value: 8.31e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 392922690   89 LSNMPLKVVDTILENVEPIDRLPLGKVSQSLRSLTK 124
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVD 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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