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Conserved domains on  [gi|442632130|ref|NP_001261801|]
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combover, isoform C [Drosophila melanogaster]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 385-720 1.60e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 1.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   385 VNGGEAPKYESVQQVQDDMASLVGRMKNLTAFIHN-QNELSTVLgddgpeilAEQEALQEKLESLRTQREDMRNLVDELN 463
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAElEKALAELR--------KELEELEEELEQLRKELEELSRQISALR 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   464 SINRAARETARVIKEKEETPTPPPKPEEAAPAAPKERVVpvEYQRNVPIIRQEAANAAQRALHAQAMINQKTADIEALKA 543
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE--EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   544 QMARLKGMLYTVSQIEESTPSMGSTLERR---SEERTSVERELPAEIAQRVFALNDVTSELRAEAASLQKERDRILALKA 620
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRledLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   621 EIERRKQQAAAAVQMGDDALKRssltptptpMRQRMTEEEDpSEVDNSLQatptKEQLRDELRSQCERLRTEYEQKQREL 700
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSE---------LRRELEELRE-KLAQLELR----LEGLEVRIDNLQERLSEEYSLTLEEA 956

                          330       340
                   ....*....|....*....|
gi 442632130   701 EQRYVASNNTTSEADDEAND 720
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKR 976
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 385-720 1.60e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 1.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   385 VNGGEAPKYESVQQVQDDMASLVGRMKNLTAFIHN-QNELSTVLgddgpeilAEQEALQEKLESLRTQREDMRNLVDELN 463
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAElEKALAELR--------KELEELEEELEQLRKELEELSRQISALR 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   464 SINRAARETARVIKEKEETPTPPPKPEEAAPAAPKERVVpvEYQRNVPIIRQEAANAAQRALHAQAMINQKTADIEALKA 543
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE--EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   544 QMARLKGMLYTVSQIEESTPSMGSTLERR---SEERTSVERELPAEIAQRVFALNDVTSELRAEAASLQKERDRILALKA 620
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRledLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   621 EIERRKQQAAAAVQMGDDALKRssltptptpMRQRMTEEEDpSEVDNSLQatptKEQLRDELRSQCERLRTEYEQKQREL 700
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSE---------LRRELEELRE-KLAQLELR----LEGLEVRIDNLQERLSEEYSLTLEEA 956

                          330       340
                   ....*....|....*....|
gi 442632130   701 EQRYVASNNTTSEADDEAND 720
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKR 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 334-704 1.91e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 1.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  334 DELQQRLEASNRNMQHLHDEQAKLLQIQNLAKTHLNEMERLRQQADSLphnvNGGEAPKYESVQQVQDDMASL---VGRM 410
Cdd:COG1196   438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE----LAEAAARLLLLLEAEADYEGFlegVKAA 513

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  411 KNLTAFIHNQNELSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVDELNSINRAARETARVIKEKEETPTPPPKPE 490
Cdd:COG1196   514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALA 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  491 EAAPAApkeRVVPVEYQRnvpiirQEAANAAQRALHAQAMINQKTADIEALKAQMARLKGMLYTVSQIEESTPSMGSTLE 570
Cdd:COG1196   594 RGAIGA---AVDLVASDL------READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  571 RRSEERTSVERELPAEIAQRvfalndvTSELRAEAASLQKERDRILALKAEIERRKQQAAAAVQMGDDALKRSSLTPTPT 650
Cdd:COG1196   665 GSRRELLAALLEAEAELEEL-------AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442632130  651 PMRQRMTEEEDPSEVDNSLQATPTKEQLRDELRsQCERLRT-----------EYEqkqrELEQRY 704
Cdd:COG1196   738 LEELLEEEELLEEEALEELPEPPDLEELERELE-RLEREIEalgpvnllaieEYE----ELEERY 797
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 530-717 3.97e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 3.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   530 MINQKTADIEALKAQMARLKGMLYTVSQI----EEST-------PSMgSTLERRS--EERTSVERELPAEIA---QRVFA 593
Cdd:pfam15921  164 MLEDSNTQIEQLRKMMLSHEGVLQEIRSIlvdfEEASgkkiyehDSM-STMHFRSlgSAISKILRELDTEISylkGRIFP 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   594 LNDVTSELRAEAAS-----LQKERDRILALKAEIErrkqqaaaaVQMGDDALKRSSLTPTPTPMRQRMTEEEDPSEVDNS 668
Cdd:pfam15921  243 VEDQLEALKSESQNkiellLQQHQDRIEQLISEHE---------VEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS 313

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 442632130   669 L------QATPTKEQLRDELRsqcERLRTeYEQKQRELEQRYVASNNTTSEADDE 717
Cdd:pfam15921  314 MymrqlsDLESTVSQLRSELR---EAKRM-YEDKIEELEKQLVLANSELTEARTE 364
mukB PRK04863
chromosome partition protein MukB;
582-704 3.89e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 3.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  582 ELPAEIAQRVF--ALNDVtSELRAEAASLQKERDRIlalkAEIERRKQQAAAAVQMGDDALKRSSLTPTPTPMRQRMTEE 659
Cdd:PRK04863  488 EVSRSEAWDVAreLLRRL-REQRHLAEQLQQLRMRL----SELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEE 562

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 442632130  660 edpsevdnslqATPTKEQLRDELRSQCERlRTEYEQKQRELEQRY 704
Cdd:PRK04863  563 -----------LEARLESLSESVSEARER-RMALRQQLEQLQARI 595
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 385-720 1.60e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 1.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   385 VNGGEAPKYESVQQVQDDMASLVGRMKNLTAFIHN-QNELSTVLgddgpeilAEQEALQEKLESLRTQREDMRNLVDELN 463
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAElEKALAELR--------KELEELEEELEQLRKELEELSRQISALR 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   464 SINRAARETARVIKEKEETPTPPPKPEEAAPAAPKERVVpvEYQRNVPIIRQEAANAAQRALHAQAMINQKTADIEALKA 543
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE--EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   544 QMARLKGMLYTVSQIEESTPSMGSTLERR---SEERTSVERELPAEIAQRVFALNDVTSELRAEAASLQKERDRILALKA 620
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRledLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   621 EIERRKQQAAAAVQMGDDALKRssltptptpMRQRMTEEEDpSEVDNSLQatptKEQLRDELRSQCERLRTEYEQKQREL 700
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSE---------LRRELEELRE-KLAQLELR----LEGLEVRIDNLQERLSEEYSLTLEEA 956

                          330       340
                   ....*....|....*....|
gi 442632130   701 EQRYVASNNTTSEADDEAND 720
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKR 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 334-704 1.91e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 1.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  334 DELQQRLEASNRNMQHLHDEQAKLLQIQNLAKTHLNEMERLRQQADSLphnvNGGEAPKYESVQQVQDDMASL---VGRM 410
Cdd:COG1196   438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE----LAEAAARLLLLLEAEADYEGFlegVKAA 513

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  411 KNLTAFIHNQNELSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVDELNSINRAARETARVIKEKEETPTPPPKPE 490
Cdd:COG1196   514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALA 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  491 EAAPAApkeRVVPVEYQRnvpiirQEAANAAQRALHAQAMINQKTADIEALKAQMARLKGMLYTVSQIEESTPSMGSTLE 570
Cdd:COG1196   594 RGAIGA---AVDLVASDL------READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  571 RRSEERTSVERELPAEIAQRvfalndvTSELRAEAASLQKERDRILALKAEIERRKQQAAAAVQMGDDALKRSSLTPTPT 650
Cdd:COG1196   665 GSRRELLAALLEAEAELEEL-------AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442632130  651 PMRQRMTEEEDPSEVDNSLQATPTKEQLRDELRsQCERLRT-----------EYEqkqrELEQRY 704
Cdd:COG1196   738 LEELLEEEELLEEEALEELPEPPDLEELERELE-RLEREIEalgpvnllaieEYE----ELEERY 797
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 334-635 3.74e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 3.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   334 DELQQRLEASNRNMQHLHDEQAKLLQIQNLAKTHLNEMERLRQQADSLPHNVNGGEAPKYESVQQVQDDMASLVGRMKNL 413
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   414 TAFIHNQNELSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVDELNSINRAARETARVIKEKEETPTPPPkpeeaa 493
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI------ 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   494 paapkervvpVEYQRNVPIIRQEAANAAQRALHAQAMINQKTADIEALKAQmarLKGMLYTVSQIEEStpsmgstLERRS 573
Cdd:TIGR02168  834 ----------AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---LEALLNERASLEEA-------LALLR 893

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442632130   574 EERTSVERELpAEIAQRVFALNDVTSELRAEAASLQKERDRilaLKAEIERRKQQAAAAVQM 635
Cdd:TIGR02168  894 SELEELSEEL-RELESKRSELRRELEELREKLAQLELRLEG---LEVRIDNLQERLSEEYSL 951
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 530-717 3.97e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 3.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   530 MINQKTADIEALKAQMARLKGMLYTVSQI----EEST-------PSMgSTLERRS--EERTSVERELPAEIA---QRVFA 593
Cdd:pfam15921  164 MLEDSNTQIEQLRKMMLSHEGVLQEIRSIlvdfEEASgkkiyehDSM-STMHFRSlgSAISKILRELDTEISylkGRIFP 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   594 LNDVTSELRAEAAS-----LQKERDRILALKAEIErrkqqaaaaVQMGDDALKRSSLTPTPTPMRQRMTEEEDPSEVDNS 668
Cdd:pfam15921  243 VEDQLEALKSESQNkiellLQQHQDRIEQLISEHE---------VEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS 313

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 442632130   669 L------QATPTKEQLRDELRsqcERLRTeYEQKQRELEQRYVASNNTTSEADDE 717
Cdd:pfam15921  314 MymrqlsDLESTVSQLRSELR---EAKRM-YEDKIEELEKQLVLANSELTEARTE 364
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 334-634 4.08e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 4.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  334 DELQQRLEASNRNMQHLHDEQAKLLQIQNLAKTHLNEMERLRQQADslphnvnggeapkyESVQQVQDDMASLVGRMKNL 413
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE--------------LELEEAQAEEYELLAELARL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  414 TAFIHNQNELSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVDELNSINRAARETARVIKEKEETPTPPPKPeeaa 493
Cdd:COG1196   301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE---- 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  494 paapkervvpveyqrnvpiIRQEAANAAQRALHAQAMINQKTADIEALKAQMARLKGmlytvsqieestpsmgsTLERRS 573
Cdd:COG1196   377 -------------------AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE-----------------RLERLE 420

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442632130  574 EERTSVERELpAEIAQRVFALNDVTSELRAEAASLQKERDRILALKAEIERRKQQAAAAVQ 634
Cdd:COG1196   421 EELEELEEAL-AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 433-645 1.14e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  433 EILAEQEALQEKLESLRTQREDmrnLVDELNSINRAARETARVIKE-------------KEETPTPPPKPEEAAPAAPKE 499
Cdd:COG4942    31 QLQQEIAELEKELAALKKEEKA---LLKQLAALERRIAALARRIRAleqelaaleaelaELEKEIAELRAELEAQKEELA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  500 RVVPVEYQRN-----VPIIRQEAANAAQRALHAQAMINQktadieALKAQMARLKGMLYTVSQIEESTPSMGSTLERRSE 574
Cdd:COG4942   108 ELLRALYRLGrqpplALLLSPEDFLDAVRRLQYLKYLAP------ARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442632130  575 ERTSVERELPAEIAQRVFALNDVTSEL---RAEAASLQKERDRILALKAEIERRKQQAAAAVQMGDDALKRSSL 645
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELaelAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 513-719 1.90e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 1.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  513 IRQEAANAAQRALHAQAMINQKTADIEALKAQMARLKgmlytvSQIEEstpsmgstLERRSEERTSVERELPAEIAQRVF 592
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELR------LELEE--------LELELEEAQAEEYELLAELARLEQ 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  593 ALNDVTSELRAEAASLQKERDRILALKAEIERRKQQAAAAVQMGDDALKrssltptptpmRQRMTEEedpsEVDNSLQAT 672
Cdd:COG1196   303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE-----------ELEEAEA----ELAEAEEAL 367

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 442632130  673 PTKEQLRDELRsqcERLRTEYEQKQRELEQRYVASNNTTSEADDEAN 719
Cdd:COG1196   368 LEAEAELAEAE---EELEELAEELLEALRAAAELAAQLEELEEAEEA 411
mukB PRK04863
chromosome partition protein MukB;
582-704 3.89e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 3.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  582 ELPAEIAQRVF--ALNDVtSELRAEAASLQKERDRIlalkAEIERRKQQAAAAVQMGDDALKRSSLTPTPTPMRQRMTEE 659
Cdd:PRK04863  488 EVSRSEAWDVAreLLRRL-REQRHLAEQLQQLRMRL----SELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEE 562

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 442632130  660 edpsevdnslqATPTKEQLRDELRSQCERlRTEYEQKQRELEQRY 704
Cdd:PRK04863  563 -----------LEARLESLSESVSEARER-RMALRQQLEQLQARI 595
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 520-702 5.73e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 5.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  520 AAQRALHAQAMINQKTADIEALKAQMARLKGMLYTVSQIEESTPSMGSTLERRSEERTSVERELPAEIAQRVFALNDVTS 599
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  600 ELRAEAASLQKERDRILALKAEIERRKQQAAAAVQMG----DDALKRSSLTPTPTPMRQRMTEeedpsEVDNSLQATPTK 675
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSpedfLDAVRRLQYLKYLAPARREQAE-----ELRADLAELAAL 165

                         170       180
                  ....*....|....*....|....*..
gi 442632130  676 EQLRDELRSQCERLRTEYEQKQRELEQ 702
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEA 192
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 334-698 8.18e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.04  E-value: 8.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   334 DELQQRLEasnRNMQHLHDEQAKLLQIQNLAKTHLNEMERLRQQADSLPHNVNGGEApKYESVQQVQDD----MASLVGR 409
Cdd:pfam10174  348 DALRLRLE---EKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQK-KIENLQEQLRDkdkqLAGLKER 423

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   410 MKNLTAFIHNQNELSTVLgddgpeilaeQEALQEK---LESLRTQRE-DMRNLVDELNSINRAAREtarvikekeetptp 485
Cdd:pfam10174  424 VKSLQTDSSNTDTALTTL----------EEALSEKeriIERLKEQRErEDRERLEELESLKKENKD-------------- 479

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   486 ppkpeeAAPAAPKERVVPVEYQRNVPIIRQEAANAAQRALHAQAMINQKTADIEALKAQMARLKGMLYTVSQIEEStpsm 565
Cdd:pfam10174  480 ------LKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEA---- 549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   566 gstlERRSEERTSVERELPAEIAQRvfalndvtselRAEAASLQKERDRILALKAEIERRKQ---------QAAAAVQMG 636
Cdd:pfam10174  550 ----VRTNPEINDRIRLLEQEVARY-----------KEESGKAQAEVERLLGILREVENEKNdkdkkiaelESLTLRQMK 614

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442632130   637 DDALKRSSLTPTPTPMRQRMTEE-EDPSEVDNSLQATPTKEQLrDELRSQCERLRTEYEQ-KQR 698
Cdd:pfam10174  615 EQNKKVANIKHGQQEMKKKGAQLlEEARRREDNLADNSQQLQL-EELMGALEKTRQELDAtKAR 677
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 332-639 2.21e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  332 SFDELQQRLEASNRNMQHLHDEQAKLLQIQNLAKthlnemERLRQQADSLphnvnggeapkyesvQQVQDDMASLVGRMK 411
Cdd:COG1196   275 ELEELELELEEAQAEEYELLAELARLEQDIARLE------ERRRELEERL---------------EELEEELAELEEELE 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  412 NLTAfihNQNELSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVDELNSINRAAREtarvikekeetptpppkpee 491
Cdd:COG1196   334 ELEE---ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE-------------------- 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  492 aapaapkervvpveyqrnvpiIRQEAANAAQRALHAQAMINQKTADIEALKAQMARLKgmlytvSQIEESTpsmgSTLER 571
Cdd:COG1196   391 ---------------------ALRAAAELAAQLEELEEAEEALLERLERLEEELEELE------EALAELE----EEEEE 439

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  572 RSEERTSVERELpAEIAQRVFALNDVTSELRAEAASLQKERDRILALKAEIERRK--QQAAAAVQMGDDA 639
Cdd:COG1196   440 EEEALEEAAEEE-AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLllLLEAEADYEGFLE 508
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 335-731 2.41e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 2.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   335 ELQQRLEASNRNMQHLHDE----------QAKLLQIQNLAKThlNEMERLRQQADSLPHNVNggeapKYESVQQVQDDma 404
Cdd:pfam05483  212 EMHFKLKEDHEKIQHLEEEykkeindkekQVSLLLIQITEKE--NKMKDLTFLLEESRDKAN-----QLEEKTKLQDE-- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   405 slvgrmkNLTAFIHNQNELSTVLGDDGPEI---LAEQEALQEKLE----SLRTQREDMRNLVDELNSinraARETARVIK 477
Cdd:pfam05483  283 -------NLKELIEKKDHLTKELEDIKMSLqrsMSTQKALEEDLQiatkTICQLTEEKEAQMEELNK----AKAAHSFVV 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   478 EKEETPTPPPKpeeaapaapkeRVVPVEYQR------NVPIIRQEAANAAQRALHAQAMINQKTADIEALKAQMARLKGM 551
Cdd:pfam05483  352 TEFEATTCSLE-----------ELLRTEQQRleknedQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKL 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   552 LYTVSQIEestpsmgstleRRSEERTSVERELPAEIAQRVFALNDVTSELRAEAASLQKERDRILALKAEIERRKQQAAA 631
Cdd:pfam05483  421 LDEKKQFE-----------KIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIE 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   632 AVQMGDD-ALKRSSLTPTPTPMRQRMTEEED-----PSEVDNSLQATPTKEQLRDELRSQCERLRTEYEQKQRELEQRYV 705
Cdd:pfam05483  490 LTAHCDKlLLENKELTQEASDMTLELKKHQEdiincKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLD 569

                          410       420
                   ....*....|....*....|....*.
gi 442632130   706 ASNNTTSEADDEANDDTDSDKYFANQ 731
Cdd:pfam05483  570 KSEENARSIEYEVLKKEKQMKILENK 595
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
328-704 3.95e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 3.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  328 DTTPSFDELQQRLEASNRNMQHLHDEQAKL-LQIQNLAKThLNEMERLR---------QQADSLPHNVNGGE-----APK 392
Cdd:PRK02224  402 DAPVDLGNAEDFLEELREERDELREREAELeATLRTARER-VEEAEALLeagkcpecgQPVEGSPHVETIEEdrervEEL 480

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  393 YESVQQVQDDMASLVGRMKNLTAFIHNQNELSTVL--GDDGPEILAEQEalqEKLESLRTQREDMRNLVDELNSINRAAR 470
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEerREDLEELIAERR---ETIEEKRERAEELRERAAELEAEAEEKR 557

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  471 ETArvikekeetptpppkpeeaapaapkervvpveyqrnvpiirQEAANAAQRALHAQAMINQKTADIEALKAQMARLKG 550
Cdd:PRK02224  558 EAA-----------------------------------------AEAEEEAEEAREEVAELNSKLAELKERIESLERIRT 596

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  551 MLYTVSQIEEstpsmgsTLERRSEERTSVErELPAEIAQRVFALNDVTSELRAEAaslqkERDRILALKAeierRKQQAA 630
Cdd:PRK02224  597 LLAAIADAED-------EIERLREKREALA-ELNDERRERLAEKRERKRELEAEF-----DEARIEEARE----DKERAE 659

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442632130  631 AAVQMGDDALkrssltptptpmrQRMTEEEDPSE-----VDNSLQATPTKEQLRDELRSQCERLRTEYEQKqRELEQRY 704
Cdd:PRK02224  660 EYLEQVEEKL-------------DELREERDDLQaeigaVENELEELEELRERREALENRVEALEALYDEA-EELESMY 724
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 334-634 4.79e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 4.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   334 DELQQRLEASNRNMQHLHDEQAKLLQIQNLAKTHL-----NEMERLRQQADSLPHNVNGGEAPKYESVQQVQDdmasLVG 408
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgeEEQLRVKEKIGELEAEIASLERSIAEKERELED----AEE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   409 RMKNLTAFIHNQNELSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVDELNSINRAARETARVIKEKEETPTPPPK 488
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   489 PEEAAPAAPKERVVPVEYQR-----NVPIIRQEAANAAQRALHAQAMINQKTADIEALKAQMARLKGMLYTVSQieestp 563
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELadlnaAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE------ 476

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442632130   564 smgsTLERRSEERTSVERELPAEIAQRVfALNDVTSELRAEAASLQKERDRILALKAEIERRKQQAAAAVQ 634
Cdd:TIGR02169  477 ----EYDRVEKELSKLQRELAEAEAQAR-ASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIE 542
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
531-702 5.93e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 5.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  531 INQKTADIEALKAQMARLKGMLYTVSQIEESTPSMGSTLERRSEERTSVERELPA-EIAQRVFALNDVTSELRAEAASLQ 609
Cdd:COG4717    73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlPLYQELEALEAELAELPERLEELE 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  610 KERDRILALKAEIERRKQQAAAAvqmgddalkrssltptptpmRQRMTEEEDPSEVDNSLQATPTKEQLrDELRSQCERL 689
Cdd:COG4717   153 ERLEELRELEEELEELEAELAEL--------------------QEELEELLEQLSLATEEELQDLAEEL-EELQQRLAEL 211

                         170
                  ....*....|...
gi 442632130  690 RTEYEQKQRELEQ 702
Cdd:COG4717   212 EEELEEAQEELEE 224
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 335-644 6.08e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 6.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   335 ELQQRLEASNRNMQHLHDEqakllqiqnlakthLNEMER----LRQQADSlphnvnggeAPKY-ESVQQVQD-DMASLVG 408
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDI--------------LNELERqlksLERQAEK---------AERYkELKAELRElELALLVL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   409 RMKNLTAFIHNQNELSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVDELNSI-----NRAARETARVIKEKEETP 483
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKElyalaNEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   484 TPPPKPEEAAPAAPKERVVPVEYQRN---------------------VPIIRQEAANAAQRALHAQAMINQKTADIEALK 542
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEElaeleekleelkeelesleaeLEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130   543 AQMARLKGML-YTVSQIEESTPSMGSTLERRSEERTSVERELPAEIAQRVfalndvtSELRAEAASLQKERDRILALKAE 621
Cdd:TIGR02168  393 LQIASLNNEIeRLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL-------EELEEELEELQEELERLEEALEE 465

                          330       340
                   ....*....|....*....|...
gi 442632130   622 IERRKQQAAAAVQMGDDALKRSS 644
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQ 488
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
310-641 8.18e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  310 NRAQSIQSLHS--------VLETPtpDTTPSFDELQQrleasnrnmqhlhdeqakllQIQNLAKTHlNEMERLRQQADSL 381
Cdd:COG4913   198 HKTQSFKPIGDlddfvreyMLEEP--DTFEAADALVE--------------------HFDDLERAH-EALEDAREQIELL 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  382 phnvngGEAP-KYESVQQVQDDMASLVGRMKNLTAFIHNQneLSTVLGDDGPEILAEQEALQEKLESLRTQREDMRNLVD 460
Cdd:COG4913   255 ------EPIReLAERYAAARERLAELEYLRAALRLWFAQR--RLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  461 ELnsinraaretarvikekeetptpppkpeeaapaapkervvpveyqrnvpiIRQEAANAAQRALHAQAMINQKTADIEA 540
Cdd:COG4913   327 EL--------------------------------------------------EAQIRGNGGDRLEQLEREIERLERELEE 356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442632130  541 LKAQMARLKGMLYTVSQIEESTPSMGSTLERRSEERTSVERELPAEIAQRVFALNDVTSELRAEAASLQKERDRILALK- 619
Cdd:COG4913   357 RERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKs 436

                         330       340
                  ....*....|....*....|....*
gi 442632130  620 ---AEIERRKQQAAAAVQMGDDALK 641
Cdd:COG4913   437 nipARLLALRDALAEALGLDEAELP 461
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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