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Conserved domains on  [gi|442634421|ref|NP_001263157|]
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uncharacterized protein Dmel_CG17684, isoform D [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DPPIV_N super family cl37636
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
147-437 2.01e-51

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


The actual alignment was detected with superfamily member pfam00930:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 177.89  E-value: 2.01e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  147 SSDLKYVLFTHNVKKNFQKSFTAFYTIYDVTNDhhTPVKLKDTlkvqRTRLQYASWLGNTTAIIFVVKNDIFIRQSPLVE 226
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETN--RVEPLPPG----EGKIQDAKWSPDGDRLAFVRDNNLYVRELATGK 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  227 EdIRITSSGhENHIYNGVPDWLYQEEIFETPEAIWTSSDGTHFMYALFNDTNVGMMTYPWlssgalfsgsgIFSGSIFPE 306
Cdd:pfam00930  75 E-IQITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPY-----------YTDEGPGPE 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  307 TKMVRFPTPGTTNPEVELWAVDITNLSdiqKFNIKPPATIYGQDYYLTSAGWISDSNcqVSVVYMGRSQNYSVISLCSKE 386
Cdd:pfam00930 142 VREIKYPKAGAPNPTVELFVYDLASGK---TVEVVPPDDLSDADYYITRVKWVPDGK--LLVQWLNRDQNRLKVVLCDAE 216
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442634421  387 EDwKCLEVHSERApeDEWLDIFPHPVFSS-DGSSFLFlanIQESENYQftHI 437
Cdd:pfam00930 217 TG-RTVVILEETS--DGWVELHQDPHFIKrDGSGFLW---ISERDGYN--HL 260
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
147-437 2.01e-51

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 177.89  E-value: 2.01e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  147 SSDLKYVLFTHNVKKNFQKSFTAFYTIYDVTNDhhTPVKLKDTlkvqRTRLQYASWLGNTTAIIFVVKNDIFIRQSPLVE 226
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETN--RVEPLPPG----EGKIQDAKWSPDGDRLAFVRDNNLYVRELATGK 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  227 EdIRITSSGhENHIYNGVPDWLYQEEIFETPEAIWTSSDGTHFMYALFNDTNVGMMTYPWlssgalfsgsgIFSGSIFPE 306
Cdd:pfam00930  75 E-IQITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPY-----------YTDEGPGPE 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  307 TKMVRFPTPGTTNPEVELWAVDITNLSdiqKFNIKPPATIYGQDYYLTSAGWISDSNcqVSVVYMGRSQNYSVISLCSKE 386
Cdd:pfam00930 142 VREIKYPKAGAPNPTVELFVYDLASGK---TVEVVPPDDLSDADYYITRVKWVPDGK--LLVQWLNRDQNRLKVVLCDAE 216
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442634421  387 EDwKCLEVHSERApeDEWLDIFPHPVFSS-DGSSFLFlanIQESENYQftHI 437
Cdd:pfam00930 217 TG-RTVVILEETS--DGWVELHQDPHFIKrDGSGFLW---ISERDGYN--HL 260
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
147-437 2.01e-51

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 177.89  E-value: 2.01e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  147 SSDLKYVLFTHNVKKNFQKSFTAFYTIYDVTNDhhTPVKLKDTlkvqRTRLQYASWLGNTTAIIFVVKNDIFIRQSPLVE 226
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETN--RVEPLPPG----EGKIQDAKWSPDGDRLAFVRDNNLYVRELATGK 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  227 EdIRITSSGhENHIYNGVPDWLYQEEIFETPEAIWTSSDGTHFMYALFNDTNVGMMTYPWlssgalfsgsgIFSGSIFPE 306
Cdd:pfam00930  75 E-IQITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPY-----------YTDEGPGPE 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634421  307 TKMVRFPTPGTTNPEVELWAVDITNLSdiqKFNIKPPATIYGQDYYLTSAGWISDSNcqVSVVYMGRSQNYSVISLCSKE 386
Cdd:pfam00930 142 VREIKYPKAGAPNPTVELFVYDLASGK---TVEVVPPDDLSDADYYITRVKWVPDGK--LLVQWLNRDQNRLKVVLCDAE 216
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 442634421  387 EDwKCLEVHSERApeDEWLDIFPHPVFSS-DGSSFLFlanIQESENYQftHI 437
Cdd:pfam00930 217 TG-RTVVILEETS--DGWVELHQDPHFIKrDGSGFLW---ISERDGYN--HL 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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