host cell factor C1 regulator 1 isoform 3 [Homo sapiens]
HPIP domain-containing protein( domain architecture ID 10633591)
HPIP domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||
HPIP | pfam15226 | HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that ... |
2-132 | 3.19e-63 | |||
HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that binds to the beta-propeller domain of HCF-1. HPIP regulates HCF-1 activity by modulating its subcellular localization. HCF-1 is a cellular protein required by VP16 to activate the herpes simplex virus- immediate-early genes. VP16 is a component of the viral tegument and, after release into the cell, binds to HCF-1 and translocates to the nucleus to form a complex with the POU domain protein Oct-1 and a VP16-responsive DNA sequence. HPIP-mediated export may provide the pool of cytoplasmic HCF-1 required for import of virion-derived VP16 into the nucleus. : Pssm-ID: 373659 Cd Length: 133 Bit Score: 189.43 E-value: 3.19e-63
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Name | Accession | Description | Interval | E-value | |||
HPIP | pfam15226 | HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that ... |
2-132 | 3.19e-63 | |||
HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that binds to the beta-propeller domain of HCF-1. HPIP regulates HCF-1 activity by modulating its subcellular localization. HCF-1 is a cellular protein required by VP16 to activate the herpes simplex virus- immediate-early genes. VP16 is a component of the viral tegument and, after release into the cell, binds to HCF-1 and translocates to the nucleus to form a complex with the POU domain protein Oct-1 and a VP16-responsive DNA sequence. HPIP-mediated export may provide the pool of cytoplasmic HCF-1 required for import of virion-derived VP16 into the nucleus. Pssm-ID: 373659 Cd Length: 133 Bit Score: 189.43 E-value: 3.19e-63
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Name | Accession | Description | Interval | E-value | |||
HPIP | pfam15226 | HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that ... |
2-132 | 3.19e-63 | |||
HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that binds to the beta-propeller domain of HCF-1. HPIP regulates HCF-1 activity by modulating its subcellular localization. HCF-1 is a cellular protein required by VP16 to activate the herpes simplex virus- immediate-early genes. VP16 is a component of the viral tegument and, after release into the cell, binds to HCF-1 and translocates to the nucleus to form a complex with the POU domain protein Oct-1 and a VP16-responsive DNA sequence. HPIP-mediated export may provide the pool of cytoplasmic HCF-1 required for import of virion-derived VP16 into the nucleus. Pssm-ID: 373659 Cd Length: 133 Bit Score: 189.43 E-value: 3.19e-63
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Blast search parameters | ||||
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