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Conserved domains on  [gi|665404614|ref|NP_001285677|]
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uncharacterized protein Dmel_CG31637, isoform B [Drosophila melanogaster]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
187-459 2.37e-10

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 60.82  E-value: 2.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  187 VVVTSWRSGSTFLGDILNSIPgnfyhyeplldfgikQIRDPDDQELAVqnLKNllNCDYADMIDyLNFGKTHTYLFEHNT 266
Cdd:pfam00685   5 LIVTYPKSGTTWLQEILSLIP---------------NRGDFEKSEEPH--LFN--NHNRSPFLE-WYPGDTYFDVAEGPV 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  267 RLWDvcREFPRFcwrpafltrfcrlfpiqsMKTvRLRLAQAEKLLEDqslSSVRIVLLVRDPRGTMQSRRHRVWC-GGNE 345
Cdd:pfam00685  65 RLNA--LPSPRI------------------IKT-HLPLHLLPKSLWD---PNAKIIYLVRNPKDVAVSYYHFFRMaKLLK 120
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  346 DCEDP----------RLVCQDLRDDYKtaEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHT- 414
Cdd:pfam00685 121 APGTPfefvedflngKVNCGSYFDHVK--GWWKLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEELDKIVKHLs 198
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665404614  415 -----------KVNIGGVSSTYRdSRSAPFHWMQDLKPEEIKQIQDVCTEAMDLWG 459
Cdd:pfam00685 199 fenmkgnpclnYSKLPKEVSPFF-RKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
187-459 2.37e-10

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 60.82  E-value: 2.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  187 VVVTSWRSGSTFLGDILNSIPgnfyhyeplldfgikQIRDPDDQELAVqnLKNllNCDYADMIDyLNFGKTHTYLFEHNT 266
Cdd:pfam00685   5 LIVTYPKSGTTWLQEILSLIP---------------NRGDFEKSEEPH--LFN--NHNRSPFLE-WYPGDTYFDVAEGPV 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  267 RLWDvcREFPRFcwrpafltrfcrlfpiqsMKTvRLRLAQAEKLLEDqslSSVRIVLLVRDPRGTMQSRRHRVWC-GGNE 345
Cdd:pfam00685  65 RLNA--LPSPRI------------------IKT-HLPLHLLPKSLWD---PNAKIIYLVRNPKDVAVSYYHFFRMaKLLK 120
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  346 DCEDP----------RLVCQDLRDDYKtaEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHT- 414
Cdd:pfam00685 121 APGTPfefvedflngKVNCGSYFDHVK--GWWKLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEELDKIVKHLs 198
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665404614  415 -----------KVNIGGVSSTYRdSRSAPFHWMQDLKPEEIKQIQDVCTEAMDLWG 459
Cdd:pfam00685 199 fenmkgnpclnYSKLPKEVSPFF-RKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
187-459 2.37e-10

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 60.82  E-value: 2.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  187 VVVTSWRSGSTFLGDILNSIPgnfyhyeplldfgikQIRDPDDQELAVqnLKNllNCDYADMIDyLNFGKTHTYLFEHNT 266
Cdd:pfam00685   5 LIVTYPKSGTTWLQEILSLIP---------------NRGDFEKSEEPH--LFN--NHNRSPFLE-WYPGDTYFDVAEGPV 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  267 RLWDvcREFPRFcwrpafltrfcrlfpiqsMKTvRLRLAQAEKLLEDqslSSVRIVLLVRDPRGTMQSRRHRVWC-GGNE 345
Cdd:pfam00685  65 RLNA--LPSPRI------------------IKT-HLPLHLLPKSLWD---PNAKIIYLVRNPKDVAVSYYHFFRMaKLLK 120
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  346 DCEDP----------RLVCQDLRDDYKtaEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHT- 414
Cdd:pfam00685 121 APGTPfefvedflngKVNCGSYFDHVK--GWWKLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEELDKIVKHLs 198
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665404614  415 -----------KVNIGGVSSTYRdSRSAPFHWMQDLKPEEIKQIQDVCTEAMDLWG 459
Cdd:pfam00685 199 fenmkgnpclnYSKLPKEVSPFF-RKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
Sulfotransfer_3 pfam13469
Sulfotransferase family;
320-404 1.22e-07

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 51.52  E-value: 1.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665404614  320 RIVLLVRDPRGTMQSRRHRVWCGGNED--CEDPRLVCQDLRDDYKTAEVLLLKY----PSRFRTVRYEDLSLSPSEMTQD 393
Cdd:pfam13469  83 KFIHLHRDPVDTVISSYCSLFGFTLSSysTAFLRDIGLALARWSRAYERLMAARarvpPGRFLDVRYEDLVADPEGTLRR 162
                          90
                  ....*....|.
gi 665404614  394 ILQFYGLPFDP 404
Cdd:pfam13469 163 ILEFLGLPWDD 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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