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Conserved domains on  [gi|808354795|ref|NP_001293296|]
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palmitoyl-protein hydrolase [Caenorhabditis elegans]

Protein Classification

alpha/beta hydrolase( domain architecture ID 10491393)

alpha/beta hydrolase similar to acyl-protein thioesterase that hydrolyzes fatty acids from S-acylated cysteine residues in proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 87-302 3.23e-113

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


:

Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 325.87  E-value: 3.23e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795   87 NGNPSIVSPRGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIKFICPHSSERPVTLNMGMRMPAWFDLFGLDPNAQEDE 166
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  167 QGINRATQYVHQLIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANN-ATPIF 245
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTkKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 808354795  246 LGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRDVKTFLSAHI 302
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 87-302 3.23e-113

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 325.87  E-value: 3.23e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795   87 NGNPSIVSPRGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIKFICPHSSERPVTLNMGMRMPAWFDLFGLDPNAQEDE 166
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  167 QGINRATQYVHQLIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANN-ATPIF 245
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTkKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 808354795  246 LGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRDVKTFLSAHI 302
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
97-303 1.54e-50

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 165.85  E-value: 1.54e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  97 GEHKGTLIFLHGLGDQGHGWADAFKtEAKHDNIKFICPHSSERPVtlnmgMRMPAWFDLFGLDPnaQEDEQGINRATQYV 176
Cdd:COG0400    2 GPAAPLVVLLHGYGGDEEDLLPLAP-ELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFLEG--REDEEGLAAAAEAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 177 HQLIDAEVAA-GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANNATPIFLGHGTDDFLV 255
Cdd:COG0400   74 AAFIDELEARyGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEALPAPEAALAGTPVFLAHGTQDPVI 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 808354795 256 PLQFGQMSEQYIKKFNPKVELHTYRgMQHSSCGEEMRDVKTFLSAHIA 303
Cdd:COG0400  154 PVERAREAAEALEAAGADVTYREYP-GGHEISPEELADARAWLAERLA 200
PRK10439 PRK10439
enterobactin/ferric enterobactin esterase; Provisional
 190-225 3.38e-03

enterobactin/ferric enterobactin esterase; Provisional


Pssm-ID: 236695 [Multi-domain]  Cd Length: 411  Bit Score: 38.84  E-value: 3.38e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 808354795 190 ASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS-SF 225
Cdd:PRK10439 287 ADRTVVAGQSFGGLAALYAGLHWPERFGCVLSQSgSF 323
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 87-302 3.23e-113

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 325.87  E-value: 3.23e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795   87 NGNPSIVSPRGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIKFICPHSSERPVTLNMGMRMPAWFDLFGLDPNAQEDE 166
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  167 QGINRATQYVHQLIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANN-ATPIF 245
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTkKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 808354795  246 LGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRDVKTFLSAHI 302
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
97-303 1.54e-50

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 165.85  E-value: 1.54e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  97 GEHKGTLIFLHGLGDQGHGWADAFKtEAKHDNIKFICPHSSERPVtlnmgMRMPAWFDLFGLDPnaQEDEQGINRATQYV 176
Cdd:COG0400    2 GPAAPLVVLLHGYGGDEEDLLPLAP-ELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFLEG--REDEEGLAAAAEAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 177 HQLIDAEVAA-GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANNATPIFLGHGTDDFLV 255
Cdd:COG0400   74 AAFIDELEARyGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEALPAPEAALAGTPVFLAHGTQDPVI 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 808354795 256 PLQFGQMSEQYIKKFNPKVELHTYRgMQHSSCGEEMRDVKTFLSAHIA 303
Cdd:COG0400  154 PVERAREAAEALEAAGADVTYREYP-GGHEISPEELADARAWLAERLA 200
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
95-293 5.40e-16

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 75.42  E-value: 5.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  95 PRGEHKGTLIFLHGLGDQGHGW---ADAFkTEAKHDnikFICphsserpvtlnmgmrmpawFDL--FGLDPNAQEDEQGI 169
Cdd:COG2267   23 PAGSPRGTVVLVHGLGEHSGRYaelAEAL-AAAGYA---VLA-------------------FDLrgHGRSDGPRGHVDSF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 170 NRATQYVHQLIDAevAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGS-------FTANNA- 241
Cdd:COG2267   80 DDYVDDLRAALDA--LRARPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPAYRADPLLGPSarwlralRLAEALa 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 808354795 242 ---TPIFLGHGTDDFLVPlqfGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRD 293
Cdd:COG2267  158 ridVPVLVLHGGADRVVP---PEAARRLAARLSPDVELVLLPGARHELLNEPARE 209
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 96-301 1.95e-11

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 62.33  E-value: 1.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  96 RGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIkfICPhsserpvtlnmgmrmpawfDL--FGLDPnAQEDEQGINRAT 173
Cdd:COG0596   19 AGPDGPPVVLLHGLPGSSYEWRPLIPALAAGYRV--IAP-------------------DLrgHGRSD-KPAGGYTLDDLA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 174 QYVHQLIDAevaAGIpaSRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSS---FFLQRTKFPGS--------FTANNAT 242
Cdd:COG0596   77 DDLAALLDA---LGL--ERVVLVGHSMGGMVALELAARHPERVAGLVLVDEvlaALAEPLRRPGLapealaalLRALART 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 808354795 243 -----------PIFLGHGTDDFLVPLQFGqmseQYIKKFNPKVELHTYRGMQHSSCGEE----MRDVKTFLSAH 301
Cdd:COG0596  152 dlrerlaritvPTLVIWGEKDPIVPPALA----RRLAELLPNAELVVLPGAGHFPPLEQpeafAAALRDFLARL 221
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
103-256 3.50e-11

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 62.95  E-value: 3.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 103 LIFLHGLGDQGHGWADAFKTEAKHDN------IK-FICphsserpVTLNMGMRmpawfdlfgldPNAQEDEQGINRATQY 175
Cdd:COG2382  115 LYLLDGGGGDEQDWFDQGRLPTILDNliaagkIPpMIV-------VMPDGGDG-----------GDRGTEGPGNDAFERF 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 176 VHQ----LIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSF---------TANNAT 242
Cdd:COG2382  177 LAEelipFVEKNYRVSADPEHRAIAGLSMGGLAALYAALRHPDLFGYVGSFSGSFWWPPGDADRGgwaellaagAPKKPL 256

                        170
                 ....*....|....
gi 808354795 243 PIFLGHGTDDFLVP 256
Cdd:COG2382  257 RFYLDVGTEDDLLE 270
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
92-285 5.14e-11

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 61.14  E-value: 5.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  92 IVSPRGEHK-GTLIFLH---GLGDQGHGWADAFkteAKHDNikficphsserpVTLnmgmrMPawfDLFGLDPNAQEDEQ 167
Cdd:COG0412   20 LARPAGGGPrPGVVVLHeifGLNPHIRDVARRL---AAAGY------------VVL-----AP---DLYGRGGPGDDPDE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 168 GINRATQYVHQLIDAEVAAGI---------PASRIAVGGFSMGGALAIYAGLTYPqklgGIVGLSSFF-LQRTKFPGSFT 237
Cdd:COG0412   77 ARALMGALDPELLAADLRAALdwlkaqpevDAGRVGVVGFCFGGGLALLAAARGP----DLAAAVSFYgGLPADDLLDLA 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 808354795 238 ANNATPIFLGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHS 285
Cdd:COG0412  153 ARIKAPVLLLYGEKDPLVPPEQVAALEAALAAAGVDVELHVYPGAGHG 200
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
187-302 1.13e-10

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 60.42  E-value: 1.13e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 187 GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSF-----FLQRTKF--------------------PGSFTANNA 241
Cdd:COG1506   89 YVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVsdlrsYYGTTREyterlmggpwedpeayaarsPLAYADKLK 168

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 808354795 242 TPIFLGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEE----MRDVKTFLSAHI 302
Cdd:COG1506  169 TPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAGapdyLERILDFLDRHL 233
COG4099 COG4099
Predicted peptidase [General function prediction only];
103-286 3.32e-10

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 59.21  E-value: 3.32e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 103 LIFLHGLGDQGHGWadafKTEAKHDNIKFICPHSSERpvtlnmgmrmpawFDLFGLDPNAQEDEQ-GINRATQYVHQLID 181
Cdd:COG4099   52 VLFLHGAGERGTDN----EKQLTHGAPKFINPENQAK-------------FPAIVLAPQCPEDDYwSDTKALDAVLALLD 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 182 aEVAA--GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSfflqrtkFPGSFTANNA--TPIFLGHGTDDFLVPL 257
Cdd:COG4099  115 -DLIAeyRIDPDRIYLTGLSMGGYGTWDLAARYPDLFAAAVPICG-------GGDPANAANLkkVPVWIFHGAKDDVVPV 186

                        170       180
                 ....*....|....*....|....*....
gi 808354795 258 QFGQMSEQYIKKFNPKVELHTYRGMQHSS 286
Cdd:COG4099  187 EESRAMVEALKAAGADVKYTEYPGVGHNS 215
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
160-284 3.75e-10

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 58.35  E-value: 3.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 160 PNAQEDeqgINRATQYVHQLIDAevaAGIPASRIAVGGFSMGGALAIYAGLTY-------PQKLGGIVGLSSFFLQrtkf 232
Cdd:COG0657   61 PAALED---AYAALRWLRANAAE---LGIDPDRIAVAGDSAGGHLAAALALRArdrggprPAAQVLIYPVLDLTAS---- 130

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 808354795 233 PGSFTANNATPIFLGHGTDDFLVPlqfgqMSEQY---IKKFNPKVELHTYRGMQH 284
Cdd:COG0657  131 PLRADLAGLPPTLIVTGEADPLVD-----ESEALaaaLRAAGVPVELHVYPGGGH 180
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 165-284 6.48e-08

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 52.61  E-value: 6.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 165 DEQGINRATQYVHQLidaevaAGIPASRIAVGGFSMGGALAIYAGLTYPQkLGGIVGLSSF------FLQRTKF------ 232
Cdd:COG1073   89 ERRDARAAVDYLRTL------PGVDPERIGLLGISLGGGYALNAAATDPR-VKAVILDSPFtsledlAAQRAKEargayl 161

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 808354795 233 --------------------PGSFTANNATPIFLGHGTDDFLVPLqfgQMSEQYIKKFNPKVELHTYRGMQH 284
Cdd:COG1073  162 pgvpylpnvrlasllndefdPLAKIEKISRPLLFIHGEKDEAVPF---YMSEDLYEAAAEPKELLIVPGAGH 230
DLH pfam01738
Dienelactone hydrolase family;
191-285 8.02e-08

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 51.97  E-value: 8.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  191 SRIAVGGFSMGGALAiYAGLTYPQKLGGIVGLSSFFLQRtkfPGSFTANNATPIFLGHGTDDFLVPLQFGQMSEQYIKKF 270
Cdd:pfam01738  96 KKVGVVGYCMGGALA-VLLAAKGPLVDAAVGFYGVGPEP---PLIEAPDIKAPILFHFGEEDHFVPADSRELIEEALKAA 171

                          90
                  ....*....|....*
gi 808354795  271 NPKVELHTYRGMQHS 285
Cdd:pfam01738 172 NVDHQIHSYPGAGHA 186
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 174-271 1.64e-07

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 51.54  E-value: 1.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 174 QYVHQLIDAEVAA-GIPASRIAVGGFSMGGALAIYAGLTYPQKL--GGIV-GLssffLQRTKFPGSFTANNATPIFLGHG 249
Cdd:COG3509  116 AFIAALVDDLAARyGIDPKRVYVTGLSAGGAMAYRLACEYPDVFaaVAPVaGL----PYGAASDAACAPGRPVPVLVIHG 191

                         90       100
                 ....*....|....*....|..
gi 808354795 250 TDDFLVPLQFGQMSEQYIKKFN 271
Cdd:COG3509  192 TADPTVPYAGAEETLAQWAALN 213
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 97-236 1.42e-06

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 48.36  E-value: 1.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795   97 GEHKGTLIFLHGLGDqgHGW-----ADAFkteAKHDnikficphsserpvtlnmgmrmpawFDLFGLD-------PNAQE 164
Cdd:pfam12146   1 GEPRAVVVLVHGLGE--HSGryahlADAL---AAQG-------------------------FAVYAYDhrghgrsDGKRG 50

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 808354795  165 DEQGINRATQYVHQLIDAeVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSF 236
Cdd:pfam12146  51 HVPSFDDYVDDLDTFVDK-IREEHPGLPLFLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPI 121
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 101-277 1.06e-04

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 42.88  E-value: 1.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  101 GTLIFLHGLGDQGHGWADAFKTEAKHDnikficphsserpvtlnmgmrmpawFDLFGLD-PNAQEDEQGINRAT------ 173
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDG-------------------------FRVIALDlRGFGKSSRPKAQDDyrtddl 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795  174 -QYVHQLIDAevaagIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSfflqrtkfpgsftanNATPIFLGHgTDD 252
Cdd:pfam00561  56 aEDLEYILEA-----LGLEKVNLVGHSMGGLIALAYAAKYPDRVKALVLLGA---------------LDPPHELDE-ADR 114

                         170       180
                  ....*....|....*....|....*
gi 808354795  253 FLVPLQFGQMSEQYIKKFNPKVELH 277
Cdd:pfam00561 115 FILALFPGFFDGFVADFAPNPLGRL 139
FrmB COG0627
S-formylglutathione hydrolase FrmB [Defense mechanisms];
102-223 1.23e-04

S-formylglutathione hydrolase FrmB [Defense mechanisms];


Pssm-ID: 440392 [Multi-domain]  Cd Length: 249  Bit Score: 42.51  E-value: 1.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 102 TLIFLHGLGDQGHGW---ADAFKTEAKHdNIKFICPhsserpvtlnMGMRMPAWFDlfgldpnAQEDEQGINRATQYVHQ 178
Cdd:COG0627   35 VLYLLHGLTGTHENWtrkTGAQRLAAEL-GVIVVMP----------DGGQASFYVD-------WTQGPAGHYRWETYLTE 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 808354795 179 ----LIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS 223
Cdd:COG0627   97 elppLIEANFPVSADRERRAIAGLSMGGHGALTLALRHPDLFRAVAAFS 145
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
191-226 6.49e-04

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 40.31  E-value: 6.49e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 808354795 191 SRIAVGGFSMGGALAIYAGLTYPQkLGGIVGLSSFF 226
Cdd:COG1647   84 DKVIVIGLSMGGLLALLLAARYPD-VAGLVLLSPAL 118
YbbA COG2819
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
190-286 1.44e-03

Predicted hydrolase of the alpha/beta superfamily [General function prediction only];


Pssm-ID: 442067 [Multi-domain]  Cd Length: 250  Bit Score: 39.58  E-value: 1.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808354795 190 ASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS-------SFFLQRTKFPGSfTANNATPIFLGHGTDDFLVPLQFG-- 260
Cdd:COG2819  129 PERTGLIGHSLGGLFSLYALLKYPDLFGRYIAISpslwwddGALLDEAEALLK-RSPLPKRLYLSVGTLEGDSMDGMVdd 207

                         90       100       110
                 ....*....|....*....|....*....|
gi 808354795 261 --QMSEQYIKKFNP--KVELHTYRGMQHSS 286
Cdd:COG2819  208 arRLAEALKAKGYPglNVKFEVFPGETHGS 237
PRK10439 PRK10439
enterobactin/ferric enterobactin esterase; Provisional
 190-225 3.38e-03

enterobactin/ferric enterobactin esterase; Provisional


Pssm-ID: 236695 [Multi-domain]  Cd Length: 411  Bit Score: 38.84  E-value: 3.38e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 808354795 190 ASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS-SF 225
Cdd:PRK10439 287 ADRTVVAGQSFGGLAALYAGLHWPERFGCVLSQSgSF 323
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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