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Conserved domains on  [gi|1063704078|ref|NP_001325079|]
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alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 60-272 1.87e-25

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 100.08  E-value: 1.87e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  60 PTKPVLLFIHGFAAeGIVTWQFQVGSLAKKYSVYIPDLLFFGGSYSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYG 139
Cdd:COG0596    21 PDGPPVVLLHGLPG-SSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDALGLERVVLVGHSMG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078 140 GMVAFKIAEEYPEMVQAMVVSGSILAmtdtisesnlnqlgfkssadlllptsvkglktlftlAVHKPMWFPKRLFKDFIE 219
Cdd:COG0596   100 GMVALELAARHPERVAGLVLVDEVLA------------------------------------ALAEPLRRPGLAPEALAA 143

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063704078 220 VMITNRkeRAELLEALvisnKDVTIPrfqqkIHLLWGESDQIFNLEFAKSMKE 272
Cdd:COG0596   144 LLRALA--RTDLRERL----ARITVP-----TLVIWGEKDPIVPPALARRLAE 185
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 60-272 1.87e-25

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 100.08  E-value: 1.87e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  60 PTKPVLLFIHGFAAeGIVTWQFQVGSLAKKYSVYIPDLLFFGGSYSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYG 139
Cdd:COG0596    21 PDGPPVVLLHGLPG-SSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDALGLERVVLVGHSMG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078 140 GMVAFKIAEEYPEMVQAMVVSGSILAmtdtisesnlnqlgfkssadlllptsvkglktlftlAVHKPMWFPKRLFKDFIE 219
Cdd:COG0596   100 GMVALELAARHPERVAGLVLVDEVLA------------------------------------ALAEPLRRPGLAPEALAA 143

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063704078 220 VMITNRkeRAELLEALvisnKDVTIPrfqqkIHLLWGESDQIFNLEFAKSMKE 272
Cdd:COG0596   144 LLRALA--RTDLRERL----ARITVP-----TLVIWGEKDPIVPPALARRLAE 185
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 63-262 4.61e-18

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 81.01  E-value: 4.61e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  63 PVLLFIHGFAAeGIVTWQFQVGSLAKK-YSVYIPDLLFFGGS--YSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYG 139
Cdd:pfam00561   1 PPVLLLHGLPG-SSDLWRKLAPALARDgFRVIALDLRGFGKSsrPKAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078 140 GMVAFKIAEEYPEMVQAMVVSGSILAMTDTISES---NLNQLGFKSSADLLLPTSVKGLKTLFTLAVHKPMWFPKRLFKD 216
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGALDPPHELDEADrfiLALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063704078 217 FI------EVMITNRKERAELLEALVISNKDV--TIPRFQQKIHLLWGESDQIF 262
Cdd:pfam00561 160 LNkrfpsgDYALAKSLVTGALLFIETWSTELRakFLGRLDEPTLIIWGDQDPLV 213
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 63-154 4.53e-11

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 62.27  E-value: 4.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  63 PVLLfIHGFAAEgIVTWQFQVGSLAKKYSVYIPDLLFFGGSYSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYGGMV 142
Cdd:PRK14875  133 PVVL-IHGFGGD-LNNWLFNHAALAAGRPVIALDLPGHGASSKAVGAGSLDELAAAVLAFLDALGIERAHLVGHSMGGAV 210

                          90
                  ....*....|..
gi 1063704078 143 AFKIAEEYPEMV 154
Cdd:PRK14875  211 ALRLAARAPQRV 222
homoserO_Ac_trn TIGR01392
homoserine O-acetyltransferase; This family describes homoserine-O-acetyltransferase, an ...
 123-159 3.58e-03

homoserine O-acetyltransferase; This family describes homoserine-O-acetyltransferase, an enzyme of methionine biosynthesis. This model has been rebuilt to identify sequences more broadly, including a number of sequences suggested to be homoserine O-acetyltransferase based on proximity to other Met biosynthesis genes. [Amino acid biosynthesis, Aspartate family]


Pssm-ID: 273596 [Multi-domain]  Cd Length: 351  Bit Score: 38.44  E-value: 3.58e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1063704078 123 LRILGIEKFTLV-GFSYGGMVAFKIAEEYPEMVQAMVV 159
Cdd:TIGR01392 120 LDHLGIEQIAAVvGGSMGGMQALEWAIDYPERVRAIVV 157
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 60-272 1.87e-25

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 100.08  E-value: 1.87e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  60 PTKPVLLFIHGFAAeGIVTWQFQVGSLAKKYSVYIPDLLFFGGSYSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYG 139
Cdd:COG0596    21 PDGPPVVLLHGLPG-SSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDALGLERVVLVGHSMG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078 140 GMVAFKIAEEYPEMVQAMVVSGSILAmtdtisesnlnqlgfkssadlllptsvkglktlftlAVHKPMWFPKRLFKDFIE 219
Cdd:COG0596   100 GMVALELAARHPERVAGLVLVDEVLA------------------------------------ALAEPLRRPGLAPEALAA 143

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063704078 220 VMITNRkeRAELLEALvisnKDVTIPrfqqkIHLLWGESDQIFNLEFAKSMKE 272
Cdd:COG0596   144 LLRALA--RTDLRERL----ARITVP-----TLVIWGEKDPIVPPALARRLAE 185
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 63-262 4.61e-18

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 81.01  E-value: 4.61e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  63 PVLLFIHGFAAeGIVTWQFQVGSLAKK-YSVYIPDLLFFGGS--YSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYG 139
Cdd:pfam00561   1 PPVLLLHGLPG-SSDLWRKLAPALARDgFRVIALDLRGFGKSsrPKAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078 140 GMVAFKIAEEYPEMVQAMVVSGSILAMTDTISES---NLNQLGFKSSADLLLPTSVKGLKTLFTLAVHKPMWFPKRLFKD 216
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGALDPPHELDEADrfiLALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063704078 217 FI------EVMITNRKERAELLEALVISNKDV--TIPRFQQKIHLLWGESDQIF 262
Cdd:pfam00561 160 LNkrfpsgDYALAKSLVTGALLFIETWSTELRakFLGRLDEPTLIIWGDQDPLV 213
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
56-162 5.65e-12

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 63.48  E-value: 5.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  56 EPQKPTKPVLLFIHGFAaEGIVTWQFQVGSLAKK-YSVYIPDLLFFGGSYSDNADRsPAFQ-----AHCLVKSLRILGIE 129
Cdd:COG2267    22 RPAGSPRGTVVLVHGLG-EHSGRYAELAEALAAAgYAVLAFDLRGHGRSDGPRGHV-DSFDdyvddLRAALDALRARPGL 99

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1063704078 130 KFTLVGFSYGGMVAFKIAEEYPEMVQAMVVSGS 162
Cdd:COG2267   100 PVVLLGHSMGGLIALLYAARYPDRVAGLVLLAP 132
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 63-154 4.53e-11

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 62.27  E-value: 4.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  63 PVLLfIHGFAAEgIVTWQFQVGSLAKKYSVYIPDLLFFGGSYSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYGGMV 142
Cdd:PRK14875  133 PVVL-IHGFGGD-LNNWLFNHAALAAGRPVIALDLPGHGASSKAVGAGSLDELAAAVLAFLDALGIERAHLVGHSMGGAV 210

                          90
                  ....*....|..
gi 1063704078 143 AFKIAEEYPEMV 154
Cdd:PRK14875  211 ALRLAARAPQRV 222
PLN02578 PLN02578
hydrolase
 63-162 1.58e-09

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 57.54  E-value: 1.58e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  63 PVLLfIHGFAAEgIVTWQFQVGSLAKKYSVYIPDLLFFGgsYSDNA--DRSPAFQAHCLVKSLRILGIEKFTLVGFSYGG 140
Cdd:PLN02578   88 PIVL-IHGFGAS-AFHWRYNIPELAKKYKVYALDLLGFG--WSDKAliEYDAMVWRDQVADFVKEVVKEPAVLVGNSLGG 163

                          90       100
                  ....*....|....*....|..
gi 1063704078 141 MVAFKIAEEYPEMVQAMVVSGS 162
Cdd:PLN02578  164 FTALSTAVGYPELVAGVALLNS 185
PLN02894 PLN02894
hydrolase, alpha/beta fold family protein
 14-162 9.67e-09

hydrolase, alpha/beta fold family protein


Pssm-ID: 215484 [Multi-domain]  Cd Length: 402  Bit Score: 55.30  E-value: 9.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  14 RLMKLAGViPYTVEL------EPGTKMNFWipketlkkTKKSDK----NFAVEPQKPTKPVLLFIHGFAA-EGIVTWQFQ 82
Cdd:PLN02894   56 RLLSLVKT-PYVQEQvnigsgPPGSKVRWF--------RSASNEprfiNTVTFDSKEDAPTLVMVHGYGAsQGFFFRNFD 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  83 vgSLAKKYSVYIPDLLFFGGS-----YSDNADRSPAFQAHCLVKSLRILGIEKFTLVGFSYGGMVAFKIAEEYPEMVQAM 157
Cdd:PLN02894  127 --ALASRFRVIAIDQLGWGGSsrpdfTCKSTEETEAWFIDSFEEWRKAKNLSNFILLGHSFGGYVAAKYALKHPEHVQHL 204


                  ....*
gi 1063704078 158 VVSGS 162
Cdd:PLN02894  205 ILVGP 209
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
57-174 5.15e-08

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 52.33  E-value: 5.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  57 PQKPTKPVLLFIHGFAAEGIVTWQFQVGSLAKK-YSVYIPDLLFFGGS-----YSDNADRSPAFQAhclVKSLRILGIEK 130
Cdd:COG1506    18 ADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRgYAVLAPDYRGYGESagdwgGDEVDDVLAAIDY---LAARPYVDPDR 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1063704078 131 FTLVGFSYGGMVAFKIAEEYPEMVQAMVVSGSILAMTDTISESN 174
Cdd:COG1506    95 IGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGTTR 138
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 65-272 9.18e-08

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 51.32  E-value: 9.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  65 LLFIHGFaaeGIVTWQFQvGSLAKKYSVYIPDLLFFGGSYSDNADRSPAFQAHCLVKSLRILGieKFTLVGFSYGGMVAF 144
Cdd:pfam12697   1 VVLVHGA---GLSAAPLA-ALLAAGVAVLAPDLPGHGSSSPPPLDLADLADLAALLDELGAAR--PVVLVGHSLGGAVAL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078 145 kiaeeypEMVQAMVVSGSILAmtdtiSESNLNQLGFKSSADLLLPTSVKGLKTLFTLAVHKPMWFPKRLFKDFIEVMITN 224
Cdd:pfam12697  75 -------AAAAAALVVGVLVA-----PLAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADAEWAAALAR 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1063704078 225 RKERAELLEALVISNkdvtIPRFQQKIHLLWGEsDQIFNLEFAKSMKE 272
Cdd:pfam12697 143 LAALLAALALLPLAA----WRDLPVPVLVLAEE-DRLVPELAQRLLAA 185
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 59-143 1.15e-06

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 45.98  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  59 KPTKPVLLFIHGFAAEGIvTWQFQVGSLAKK-YSVYIPDLLFFGGSYSDNADRspafQAHCLVKSLRILGIEKFTLVGFS 137
Cdd:COG1075     2 AATRYPVVLVHGLGGSAA-SWAPLAPRLRAAgYPVYALNYPSTNGSIEDSAEQ----LAAFVDAVLAATGAEKVDLVGHS 76


                  ....*.
gi 1063704078 138 YGGMVA 143
Cdd:COG1075    77 MGGLVA 82
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
59-168 2.88e-06

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 47.24  E-value: 2.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  59 KPTKPVLLFIHGFAAegivTwQFQVGSLAKK-----YSVYIPDLLFFGGSYSDNADRSPAFQAHCLVKSLRIL--GIEKF 131
Cdd:COG1647    12 EGGRKGVLLLHGFTG----S-PAEMRPLAEAlakagYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILkaGYDKV 86

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1063704078 132 TLVGFSYGGMVAFKIAEEYPEmVQAMVVSGSILAMTD 168
Cdd:COG1647    87 IVIGLSMGGLLALLLAARYPD-VAGLVLLSPALKIDD 122
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 58-114 3.42e-06

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 47.53  E-value: 3.42e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063704078  58 QKPTKPVLLFIHGFAAEgIVTWQFQVGSLAKKYSVYIPDLLFFGGSysdnaDRSPAF 114
Cdd:PLN02679   84 VTSSGPPVLLVHGFGAS-IPHWRRNIGVLAKNYTVYAIDLLGFGAS-----DKPPGF 134
PRK11126 PRK11126
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional
 61-143 9.15e-05

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional


Pssm-ID: 236855 [Multi-domain]  Cd Length: 242  Bit Score: 42.90  E-value: 9.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  61 TKPVLLFIHGF---AAEgivtWQfQVGSLAKKYSVYIPDLLFFGGSysdnADRSPAFQAHC---LVKSLRILGIEKFTLV 134
Cdd:PRK11126    1 GLPWLVFLHGLlgsGQD----WQ-PVGEALPDYPRLYIDLPGHGGS----AAISVDGFADVsrlLSQTLQSYNILPYWLV 71


                  ....*....
gi 1063704078 135 GFSYGGMVA 143
Cdd:PRK11126   72 GYSLGGRIA 80
PRK08775 PRK08775
homoserine O-succinyltransferase;
99-159 1.68e-04

homoserine O-succinyltransferase;


Pssm-ID: 181553 [Multi-domain]  Cd Length: 343  Bit Score: 42.47  E-value: 1.68e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063704078  99 FFGGSYSDNADRSPAFQAHCLVKSLRILGIEK-FTLVGFSYGGMVAFKIAEEYPEMVQAMVV 159
Cdd:PRK08775  107 FIGADGSLDVPIDTADQADAIALLLDALGIARlHAFVGYSYGALVGLQFASRHPARVRTLVV 168
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 60-161 1.00e-03

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 39.51  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  60 PTKPVLLFIHGFAaEGIVTWQFQVGSLAKK-YSVYIPDLLFFGGSysDNAD-RSPAFQ-----AHCLVKSLR-ILGIEKF 131
Cdd:pfam12146   2 EPRAVVVLVHGLG-EHSGRYAHLADALAAQgFAVYAYDHRGHGRS--DGKRgHVPSFDdyvddLDTFVDKIReEHPGLPL 78

                          90       100       110
                  ....*....|....*....|....*....|
gi 1063704078 132 TLVGFSYGGMVAFKIAEEYPEMVQAMVVSG 161
Cdd:pfam12146  79 FLLGHSMGGLIAALYALRYPDKVDGLILSA 108
PRK10566 PRK10566
esterase; Provisional
 63-161 1.26e-03

esterase; Provisional


Pssm-ID: 182555 [Multi-domain]  Cd Length: 249  Bit Score: 39.20  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  63 PVLLFIHGFAAEGIVTWQFQVgSLAKK-YSVYIPDLLFFGGSYSDNADRS---------------PAFQAHCLVKSLrIL 126
Cdd:PRK10566   28 PTVFFYHGFTSSKLVYSYFAV-ALAQAgFRVIMPDAPMHGARFSGDEARRlnhfwqillqnmqefPTLRAAIREEGW-LL 105

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1063704078 127 GiEKFTLVGFSYGGMVAFKIAEEYPEM--VQAMVVSG 161
Cdd:PRK10566  106 D-DRLAVGGASMGGMTALGIMARHPWVkcVASLMGSG 141
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
55-160 1.94e-03

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 38.79  E-value: 1.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  55 VEPQKPTK-PVLLFIHGFAaeGIVTWQFQVGS-LAKK-YSVYIPDLLFFGGSYSDNADRSPAFQAHCL------------ 119
Cdd:COG0412    21 ARPAGGGPrPGVVVLHEIF--GLNPHIRDVARrLAAAgYVVLAPDLYGRGGPGDDPDEARALMGALDPellaadlraald 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1063704078 120 -VKSLRILGIEKFTLVGFSYGGMVAFKIAEEYPEmVQAmVVS 160
Cdd:COG0412    99 wLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPD-LAA-AVS 138
PRK10349 PRK10349
pimeloyl-ACP methyl ester esterase BioH;
65-162 2.07e-03

pimeloyl-ACP methyl ester esterase BioH;


Pssm-ID: 137836 [Multi-domain]  Cd Length: 256  Bit Score: 38.85  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704078  65 LLFIHGFAAEGIVtWQFQVGSLAKKYSVYIPDLLFFGgsysdnadRSPAFQAHCLVKSLRIL---GIEKFTLVGFSYGGM 141
Cdd:PRK10349   16 LVLLHGWGLNAEV-WRCIDEELSSHFTLHLVDLPGFG--------RSRGFGALSLADMAEAVlqqAPDKAIWLGWSLGGL 86

                          90       100
                  ....*....|....*....|.
gi 1063704078 142 VAFKIAEEYPEMVQAMVVSGS 162
Cdd:PRK10349   87 VASQIALTHPERVQALVTVAS 107
homoserO_Ac_trn TIGR01392
homoserine O-acetyltransferase; This family describes homoserine-O-acetyltransferase, an ...
 123-159 3.58e-03

homoserine O-acetyltransferase; This family describes homoserine-O-acetyltransferase, an enzyme of methionine biosynthesis. This model has been rebuilt to identify sequences more broadly, including a number of sequences suggested to be homoserine O-acetyltransferase based on proximity to other Met biosynthesis genes. [Amino acid biosynthesis, Aspartate family]


Pssm-ID: 273596 [Multi-domain]  Cd Length: 351  Bit Score: 38.44  E-value: 3.58e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1063704078 123 LRILGIEKFTLV-GFSYGGMVAFKIAEEYPEMVQAMVV 159
Cdd:TIGR01392 120 LDHLGIEQIAAVvGGSMGGMQALEWAIDYPERVRAIVV 157
MET2 COG2021
Homoserine O-acetyltransferase [Amino acid transport and metabolism]; Homoserine ...
 123-159 3.72e-03

Homoserine O-acetyltransferase [Amino acid transport and metabolism]; Homoserine O-acetyltransferase is part of the Pathway/BioSystem: Methionine biosynthesis


Pssm-ID: 441624 [Multi-domain]  Cd Length: 355  Bit Score: 38.15  E-value: 3.72e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1063704078 123 LRILGIEKF-TLVGFSYGGMVAFKIAEEYPEMVQAMVV 159
Cdd:COG2021   121 LDHLGIERLaAVIGGSMGGMQALEWAVSYPDRVRRAIV 158
PRK07581 PRK07581
hypothetical protein; Validated
 99-162 8.62e-03

hypothetical protein; Validated


Pssm-ID: 236060 [Multi-domain]  Cd Length: 339  Bit Score: 37.22  E-value: 8.62e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063704078  99 FFGGSYSDNAdrspAFQaHCLVKslRILGIEKFTLV-GFSYGGMVAFKIAEEYPEMVQ-AMVVSGS 162
Cdd:PRK07581  100 FPHVTIYDNV----RAQ-HRLLT--EKFGIERLALVvGWSMGAQQTYHWAVRYPDMVErAAPIAGT 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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