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Conserved domains on  [gi|1063725926|ref|NP_001328145|]
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cyclin-dependent kinase-activating kinase assembly factor-related / CDK-activating kinase assembly factor-like protein [Arabidopsis thaliana]

Protein Classification

MAT1 superfamily-containing protein( domain architecture ID 1907927)

MAT1 superfamily-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MAT1 super family cl44421
CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for ...
 9-66 1.44e-22

CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.


The actual alignment was detected with superfamily member pfam06391:

Pssm-ID: 461894 [Multi-domain]  Cd Length: 202  Bit Score: 88.84  E-value: 1.44e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063725926   9 YNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 66
Cdd:pfam06391  30 FNKTEEDFPSLREYNDYLEEVEDIVFNLTNGIDVEETEKKIEQYEKENKDLILKNKMK 87
 
Name Accession Description Interval E-value
MAT1 pfam06391
CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for ...
 9-66 1.44e-22

CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.


Pssm-ID: 461894 [Multi-domain]  Cd Length: 202  Bit Score: 88.84  E-value: 1.44e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063725926   9 YNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 66
Cdd:pfam06391  30 FNKTEEDFPSLREYNDYLEEVEDIVFNLTNGIDVEETEKKIEQYEKENKDLILKNKMK 87
cdk7 TIGR00570
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ...
 1-66 1.49e-18

CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129661 [Multi-domain]  Cd Length: 309  Bit Score: 80.23  E-value: 1.49e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063725926   1 MRYRFILRYNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 66
Cdd:TIGR00570  74 IRKRVLKIYNKREEDFPSLREYNDYLEEVEDIVYNLTNNIDLENTKKKIETYQKENKDVIQKNKEK 139
TFB3 COG5220
Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision ...
 1-66 4.95e-13

Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3 [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair];


Pssm-ID: 227545 [Multi-domain]  Cd Length: 314  Bit Score: 65.03  E-value: 4.95e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1063725926   1 MRYRFILRYNRREEEF-PSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 66
Cdd:COG5220    84 VRKRLLRAFNKEEEEFgGDLAKYNDYLEEVEELVFELLELIDVSLTEEKVKKYEEMNQDSILNNLER 150
 
Name Accession Description Interval E-value
MAT1 pfam06391
CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for ...
 9-66 1.44e-22

CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.


Pssm-ID: 461894 [Multi-domain]  Cd Length: 202  Bit Score: 88.84  E-value: 1.44e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063725926   9 YNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 66
Cdd:pfam06391  30 FNKTEEDFPSLREYNDYLEEVEDIVFNLTNGIDVEETEKKIEQYEKENKDLILKNKMK 87
cdk7 TIGR00570
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ...
 1-66 1.49e-18

CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129661 [Multi-domain]  Cd Length: 309  Bit Score: 80.23  E-value: 1.49e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063725926   1 MRYRFILRYNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 66
Cdd:TIGR00570  74 IRKRVLKIYNKREEDFPSLREYNDYLEEVEDIVYNLTNNIDLENTKKKIETYQKENKDVIQKNKEK 139
TFB3 COG5220
Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision ...
 1-66 4.95e-13

Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3 [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair];


Pssm-ID: 227545 [Multi-domain]  Cd Length: 314  Bit Score: 65.03  E-value: 4.95e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1063725926   1 MRYRFILRYNRREEEF-PSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 66
Cdd:COG5220    84 VRKRLLRAFNKEEEEFgGDLAKYNDYLEEVEELVFELLELIDVSLTEEKVKKYEEMNQDSILNNLER 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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